Atsushi Takeda

Atsushi Takeda

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Atsushi Takeda

Publications by authors named "Atsushi Takeda"

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CA1 LTP Attenuated by Corticosterone is Canceled by Effusol via Rescuing Intracellular Zn Dysregulation.

Cell Mol Neurobiol 2019 Oct 30;39(7):975-983. Epub 2019 May 30.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

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http://dx.doi.org/10.1007/s10571-019-00693-5DOI Listing
October 2019

[What is the Best Initial Treatment for Parkinson's Disease? New Clinical Practice Guideline and My Personal Opinion].

Authors:
Atsushi Takeda

Brain Nerve 2019 Aug;71(8):857-867

National Hospital Organization Sendai-Nishitaga Hospital.

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http://dx.doi.org/10.11477/mf.1416201366DOI Listing
August 2019

Amyloid β-Induced Rapid Zn Influx into Dentate Granule Cells Attenuates Maintained LTP Followed by Retrograde Amnesia.

Mol Neurobiol 2019 Jul 20;56(7):5041-5050. Epub 2018 Nov 20.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

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http://dx.doi.org/10.1007/s12035-018-1429-6DOI Listing
July 2019

Blockade of Rapid Influx of Extracellular Zn into Nigral Dopaminergic Neurons Overcomes Paraquat-Induced Parkinson's Disease in Rats.

Mol Neurobiol 2019 Jun 19;56(6):4539-4548. Epub 2018 Oct 19.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

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http://dx.doi.org/10.1007/s12035-018-1398-9DOI Listing
June 2019

Intake of Heated Leaf Extract of Coriandrum sativum Contributes to Resistance to Oxidative Stress via Decreases in Heavy Metal Concentrations in the Kidney.

Plant Foods Hum Nutr 2019 Jun;74(2):204-209

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

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http://dx.doi.org/10.1007/s11130-019-00720-2DOI Listing
June 2019

Extracellular Zn-independently attenuated LTP by human amyloid β and rat amyloid β.

Biochem Biophys Res Commun 2019 Jun 10;514(3):888-892. Epub 2019 May 10.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.05.037DOI Listing
June 2019

Difference in ability for extracellular Zn influx between human and rat amyloid β and its significance.

Neurotoxicology 2019 05 18;72:1-5. Epub 2019 Jan 18.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.neuro.2019.01.005DOI Listing
May 2019

Paraquat as an Environmental Risk Factor in Parkinson's Disease Accelerates Age-Related Degeneration Via Rapid Influx of Extracellular Zn into Nigral Dopaminergic Neurons.

Mol Neurobiol 2019 May 22. Epub 2019 May 22.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

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http://dx.doi.org/10.1007/s12035-019-01642-5DOI Listing
May 2019

In vivo synaptic activity-independent co-uptakes of amyloid β and Zn into dentate granule cells in the normal brain.

Sci Rep 2019 Apr 24;9(1):6498. Epub 2019 Apr 24.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

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http://dx.doi.org/10.1038/s41598-019-43012-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482136PMC
April 2019

Rasagiline monotherapy in early Parkinson's disease: A phase 3, randomized study in Japan.

Parkinsonism Relat Disord 2019 Mar 1;60:146-152. Epub 2018 Sep 1.

Department of Neurology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1016/j.parkreldis.2018.08.024DOI Listing
March 2019

Long-term safety and efficacy of adjunctive rasagiline in levodopa-treated Japanese patients with Parkinson's disease.

J Neural Transm (Vienna) 2019 Mar 11;126(3):289-297. Epub 2019 Jan 11.

Department of Neurology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1007/s00702-018-1962-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449487PMC
March 2019

Long-term, open-label, phase 3 study of rasagiline in Japanese patients with early Parkinson's disease.

J Neural Transm (Vienna) 2019 Mar 28;126(3):299-308. Epub 2019 Jan 28.

Department of Neurology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1007/s00702-018-1964-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449288PMC
March 2019

Rapid Intracellular Zn Dysregulation via Membrane Corticosteroid Receptor Activation Affects In Vivo CA1 LTP.

Mol Neurobiol 2019 Feb 8;56(2):1356-1365. Epub 2018 Jun 8.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

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http://dx.doi.org/10.1007/s12035-018-1159-9DOI Listing
February 2019

Foreword.

Authors:
Atsushi Takeda

Biol Pharm Bull 2018;41(7):994

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka.

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http://dx.doi.org/10.1248/bpb.b18-ctf4107DOI Listing
February 2019

Extracellular Zn Influx into Nigral Dopaminergic Neurons Plays a Key Role for Pathogenesis of 6-Hydroxydopamine-Induced Parkinson's Disease in Rats.

Mol Neurobiol 2019 Jan 29;56(1):435-443. Epub 2018 Apr 29.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

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http://dx.doi.org/10.1007/s12035-018-1075-zDOI Listing
January 2019

Age-Dependent Modification of Intracellular Zn Buffering in the Hippocampus and Its Impact.

Biol Pharm Bull 2019 ;42(7):1070-1075

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka.

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http://dx.doi.org/10.1248/bpb.b18-00631DOI Listing
January 2019

Negative mood invites psychotic false perception in dementia.

PLoS One 2018 1;13(6):e0197968. Epub 2018 Jun 1.

Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, Sendai, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197968PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983458PMC
December 2018

AMPA-induced extracellular Zn influx into nigral dopaminergic neurons causes movement disorder in rats.

Neurotoxicology 2018 12 31;69:23-28. Epub 2018 Aug 31.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0161813X183026
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http://dx.doi.org/10.1016/j.neuro.2018.08.008DOI Listing
December 2018

Adrenergic β receptor activation in the basolateral amygdala, which is intracellular Zn-dependent, rescues amyloid β-induced attenuation of dentate gyrus LTP.

Neurochem Int 2018 11 17;120:43-48. Epub 2018 Jul 17.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.neuint.2018.07.005DOI Listing
November 2018

Novel Defense by Metallothionein Induction Against Cognitive Decline: From Amyloid β-Induced Excess Zn to Functional Zn Deficiency.

Mol Neurobiol 2018 Oct 19;55(10):7775-7788. Epub 2018 Feb 19.

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, 3052, Australia.

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http://dx.doi.org/10.1007/s12035-018-0948-5DOI Listing
October 2018

Yokukansan, a Herbal Medicine in Japan, Buffers Social Crowding Stress via Ameliorating Glucocorticoid Secretion Response to Vasopressin.

Biol Pharm Bull 2018 ;41(6):920-924

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka.

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http://dx.doi.org/10.1248/bpb.b18-00052DOI Listing
October 2018

Defining visual illusions in Parkinson's disease: Kinetopsia and object misidentification illusions.

Parkinsonism Relat Disord 2018 10 28;55:111-116. Epub 2018 May 28.

Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University School of Medicine, Sendai, Japan.

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http://dx.doi.org/10.1016/j.parkreldis.2018.05.023DOI Listing
October 2018

Is Vulnerability of the Dentate Gyrus to Aging and Amyloid-β Neurotoxicity Linked with Modified Extracellular Zn Dynamics?

Biol Pharm Bull 2018 ;41(7):995-1000

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka.

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http://dx.doi.org/10.1248/bpb.b17-00871DOI Listing
October 2018

Weakened Intracellular Zn-Buffering in the Aged Dentate Gyrus and Its Involvement in Erasure of Maintained LTP.

Mol Neurobiol 2018 May 25;55(5):3856-3865. Epub 2017 May 25.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

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http://link.springer.com/10.1007/s12035-017-0615-2
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http://dx.doi.org/10.1007/s12035-017-0615-2DOI Listing
May 2018

Characteristic of Extracellular Zn Influx in the Middle-Aged Dentate Gyrus and Its Involvement in Attenuation of LTP.

Mol Neurobiol 2018 03 13;55(3):2185-2195. Epub 2017 Mar 13.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

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http://dx.doi.org/10.1007/s12035-017-0472-zDOI Listing
March 2018

Maintained LTP and Memory Are Lost by Zn Influx into Dentate Granule Cells, but Not Ca Influx.

Mol Neurobiol 2018 02 7;55(2):1498-1508. Epub 2017 Feb 7.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

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http://dx.doi.org/10.1007/s12035-017-0428-3DOI Listing
February 2018

The Impact of Synaptic Zn Dynamics on Cognition and Its Decline.

Int J Mol Sci 2017 Nov 14;18(11). Epub 2017 Nov 14.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan.

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http://dx.doi.org/10.3390/ijms18112411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713379PMC
November 2017

Blockade of intracellular Zn signaling in the basolateral amygdala affects object recognition memory via attenuation of dentate gyrus LTP.

Neurochem Int 2017 Sep 26;108:1-6. Epub 2017 Jan 26.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.neuint.2017.01.014DOI Listing
September 2017

Deconstructing psychosis and misperception symptoms in Parkinson's disease.

J Neurol Neurosurg Psychiatry 2017 09 9;88(9):722-729. Epub 2017 Jun 9.

Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University School of Medicine, Sendai, Japan.

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http://dx.doi.org/10.1136/jnnp-2017-315741DOI Listing
September 2017

Involvement of intracellular Zn signaling in LTP at perforant pathway-CA1 pyramidal cell synapse.

Hippocampus 2017 07 13;27(7):777-783. Epub 2017 Apr 13.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

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http://dx.doi.org/10.1002/hipo.22730DOI Listing
July 2017

Pathogen exploitation of an abscisic acid- and jasmonate-inducible MAPK phosphatase and its interception by immunity.

Proc Natl Acad Sci U S A 2017 07 26;114(28):7456-7461. Epub 2017 Jun 26.

Department of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany;

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http://dx.doi.org/10.1073/pnas.1702613114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514735PMC
July 2017

Extracellular Zn Is Essential for Amyloid β-Induced Cognitive Decline in the Normal Brain and Its Rescue.

J Neurosci 2017 07 26;37(30):7253-7262. Epub 2017 Jun 26.

Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, 3052 Victoria, Australia.

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http://dx.doi.org/10.1523/JNEUROSCI.0954-17.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705735PMC
July 2017

Significance of Low Nanomolar Concentration of Zn in Artificial Cerebrospinal Fluid.

Mol Neurobiol 2017 05 16;54(4):2477-2482. Epub 2016 Mar 16.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52- 1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

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http://link.springer.com/10.1007/s12035-016-9816-3
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http://dx.doi.org/10.1007/s12035-016-9816-3DOI Listing
May 2017

Involvement of hippocampal excitability in amyloid β-induced behavioral and psychological symptoms of dementia.

J Toxicol Sci 2016 ;41(4):449-57

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka.

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http://dx.doi.org/10.2131/jts.41.449DOI Listing
April 2017

Bathing in carbon dioxide-enriched water alters protein expression in keratinocytes of skin tissue in rats.

Int J Biometeorol 2017 Apr 5;61(4):739-746. Epub 2016 Oct 5.

Institute of Pathology, University Hospital of Essen, University of Duisburg-Essen, Hufelandstr. 55, 45147, Essen, Germany.

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http://dx.doi.org/10.1007/s00484-016-1252-6DOI Listing
April 2017

Striatal molecular imaging of presynaptic markers: Ready, fire, aim.

Neurology 2017 04 10;88(15):1388-1389. Epub 2017 Mar 10.

From the Department of Neurology (A.T.), National Hospital Organization, Sendai-Nishitaga Hospital, Sendai, Miyagi, Japan; and Departments of Neurology, Radiology, and Neuroscience and Programs in Physical Therapy and Occupational Therapy (J.S.P.), Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.1212/WNL.0000000000003827DOI Listing
April 2017

Interconnections between mRNA degradation and RDR-dependent siRNA production in mRNA turnover in plants.

J Plant Res 2017 Mar 14;130(2):211-226. Epub 2017 Feb 14.

Department of Biotechnology, Graduate School of Life Sciences, Ritsumeikan University, Shiga, 525-8577, Japan.

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http://dx.doi.org/10.1007/s10265-017-0906-8DOI Listing
March 2017

IL-17A promotes neutrophilic inflammation and disturbs acute wound healing in skin.

Exp Dermatol 2017 02 16;26(2):137-144. Epub 2016 Nov 16.

Department of Plastic and Reconstructive Surgery, Tohoku University, Sendai, Japan.

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http://dx.doi.org/10.1111/exd.13115DOI Listing
February 2017

In vitro and in vivo physiology of low nanomolar concentrations of Zn in artificial cerebrospinal fluid.

Sci Rep 2017 02 17;7:42897. Epub 2017 Feb 17.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52- 1 Yada, Suruga-ku, Shizuoka 422-8526, Japan.

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http://dx.doi.org/10.1038/srep42897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314341PMC
February 2017

Regulation of extracellular Zn(2+) homeostasis in the hippocampus as a therapeutic target for Alzheimer's disease.

Expert Opin Ther Targets 2015 27;19(8):1051-8. Epub 2015 Mar 27.

University of Shizuoka, School of Pharmaceutical Sciences, Department of Neurophysiology , 52-1 Yada, Suruga-ku, Shizuoka 422-8526 , Japan +81 54 264 5733 ; +81 54 264 5909 ;

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http://dx.doi.org/10.1517/14728222.2015.1029454DOI Listing
January 2017

Longitudinal study of cognitive and cerebral metabolic changes in Parkinson's disease.

J Neurol Sci 2017 Jan 1;372:288-293. Epub 2016 Dec 1.

Department of Behavioral Neurology & Cognitive Neuroscience, Tohoku University Graduate School of Medicine, Japan.

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http://dx.doi.org/10.1016/j.jns.2016.11.068DOI Listing
January 2017

Olfactory dysfunction.

Nihon Rinsho 2017 Jan;75(1):119-123

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January 2017

Significance of synaptic Zn signaling in zincergic and non-zincergic synapses in the hippocampus in cognition.

J Trace Elem Med Biol 2016 Dec 10;38:93-98. Epub 2016 Mar 10.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0946672X163002
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http://dx.doi.org/10.1016/j.jtemb.2016.03.003DOI Listing
December 2016

Innervation from the entorhinal cortex to the dentate gyrus and the vulnerability to Zn.

J Trace Elem Med Biol 2016 Dec 24;38:19-23. Epub 2016 May 24.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan.

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http://dx.doi.org/10.1016/j.jtemb.2016.05.006DOI Listing
December 2016

Insight into cognitive decline from Zn dynamics through extracellular signaling of glutamate and glucocorticoids.

Arch Biochem Biophys 2016 Dec 5;611:93-99. Epub 2016 Jul 5.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S00039861163021
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http://dx.doi.org/10.1016/j.abb.2016.06.021DOI Listing
December 2016

Bathing in carbon dioxide-enriched water alters protein expression in keratinocytes of skin tissue in rats.

Int J Biometeorol 2017 Apr 5;61(4):739-746. Epub 2016 Oct 5.

Institute of Pathology, University Hospital of Essen, University of Duisburg-Essen, Hufelandstr. 55, 45147, Essen, Germany.

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http://dx.doi.org/10.1007/s00484-016-1252-6DOI Listing
April 2017

In vivo visualization of tau deposits in corticobasal syndrome by 18F-THK5351 PET.

Neurology 2016 Nov 28;87(22):2309-2316. Epub 2016 Oct 28.

From the Departments of Neurology (A.K., T.H., T.B., N.S., R.O., S.Y., J.K., M.E., M.A.), Pharmacology (N.O., R.H., K.Y.), and Diagnostic Radiology (S.M.), Tohoku University Graduate School of Medicine; Divisions of Cyclotron Nuclear Medicine (S.W., K.H., M.T.) and Radiopharmaceutical Chemistry (Y.F., R.I., S.F.), Cyclotron and Radioisotope Center, and Department of Geriatric and Respiratory Medicine (A.I., K.F., H.A.) and Division of Neuroimaging (Y.K.), Institute of Development, Aging and Cancer, Tohoku University; Department of Neurology (M.K.), Tohoku Pharmaceutical University Hospital; Department of Neurology (O.T.), Sendai Medical Center; and Department of Neurology (A.T.), National Hospital Organization, Sendai Nishitaga Hospital, Sendai, Japan.

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http://dx.doi.org/10.1212/WNL.0000000000003375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135024PMC
November 2016

Influences of yokukansankachimpihange on aggressive behavior of zinc-deficient mice and actions of the ingredients on excessive neural exocytosis in the hippocampus of zinc-deficient rats.

Exp Anim 2016 Nov 30;65(4):353-361. Epub 2016 May 30.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52- 1 Yada, Shizuoka 422-8526, Japan.

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http://dx.doi.org/10.1538/expanim.16-0028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111838PMC
November 2016

Relationship Between Humeral Retroversion and Length of Baseball Career Before the Age of 16 Years.

Am J Sports Med 2016 Sep 8;44(9):2220-4. Epub 2016 Jul 8.

Department of Orthopedic Surgery, Osaka Medical College, Takatsuki, Japan.

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http://dx.doi.org/10.1177/0363546516651864DOI Listing
September 2016

Behavioral Abnormality Induced by Enhanced Hypothalamo-Pituitary-Adrenocortical Axis Activity under Dietary Zinc Deficiency and Its Usefulness as a Model.

Int J Mol Sci 2016 Jul 16;17(7). Epub 2016 Jul 16.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan.

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http://dx.doi.org/10.3390/ijms17071149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964522PMC
July 2016

Isolated glenohumeral range of motion, excluding side-to-side difference in humeral retroversion, in asymptomatic high-school baseball players.

Knee Surg Sports Traumatol Arthrosc 2016 Jun 31;24(6):1911-7. Epub 2014 Jul 31.

Department of Orthopedic Surgery, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, Osaka, 569-8686, Japan.

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http://dx.doi.org/10.1007/s00167-014-3193-0DOI Listing
June 2016

Distraction osteogenesis of the sternum for thoracic expansion in a severe case of jeune syndrome: a preliminary report.

J Plast Surg Hand Surg 2016 Jun 24;50(3):180-3. Epub 2016 Mar 24.

a Department of Plastic and Reconstructive Surgery , Tohoku University Graduate School of Medicine , Sendai , Japan ;

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http://dx.doi.org/10.3109/2000656X.2016.1147736DOI Listing
June 2016

Significance of the degree of synaptic Zn²⁺ signaling in cognition.

Biometals 2016 Apr 24;29(2):177-85. Epub 2015 Dec 24.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

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http://dx.doi.org/10.1007/s10534-015-9907-zDOI Listing
April 2016

Loss of awareness of hyposmia is associated with mild cognitive impairment in Parkinson's disease.

Parkinsonism Relat Disord 2016 Jan 21;22:74-9. Epub 2015 Nov 21.

Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, Japan.

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http://dx.doi.org/10.1016/j.parkreldis.2015.11.015DOI Listing
January 2016

Amyloid β-mediated Zn2+ influx into dentate granule cells transiently induces a short-term cognitive deficit.

PLoS One 2014 23;9(12):e115923. Epub 2014 Dec 23.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan; Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115923PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275254PMC
December 2015

Modification of hippocampal excitability in brain slices pretreated with a low nanomolar concentration of Zn2+.

J Neurosci Res 2015 Nov 13;93(11):1641-7. Epub 2015 Aug 13.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.

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http://doi.wiley.com/10.1002/jnr.23629
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http://dx.doi.org/10.1002/jnr.23629DOI Listing
November 2015

Melanin production through novel processing of proopiomelanocortin in the extracellular compartment of the auricular skin of C57BL/6 mice after UV-irradiation.

Sci Rep 2015 Sep 29;5:14579. Epub 2015 Sep 29.

Laboratory of Bioorganic Chemistry School of Pharmaceutical Sciences University of Shizuoka, 52-1 Yada, Shizuoka 422-8526, Japan.

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http://dx.doi.org/10.1038/srep14579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586518PMC
September 2015

Blockade of intracellular Zn2+ signaling in the dentate gyrus erases recognition memory via impairment of maintained LTP.

Hippocampus 2015 Aug 11;25(8):952-62. Epub 2015 Feb 11.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, Suruga-Ku, Shizuoka, Japan.

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http://dx.doi.org/10.1002/hipo.22418DOI Listing
August 2015

Is interaction of amyloid β-peptides with metals involved in cognitive activity?

Metallomics 2015 Aug;7(8):1205-12

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan.

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http://dx.doi.org/10.1039/c5mt00076aDOI Listing
August 2015

Excess influx of Zn(2+) into dentate granule cells affects object recognition memory via attenuated LTP.

Neurochem Int 2015 Aug 1;87:60-5. Epub 2015 Jun 1.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.neuint.2015.05.006DOI Listing
August 2015

Pareidolia in Parkinson's disease without dementia: A positron emission tomography study.

Parkinsonism Relat Disord 2015 Jun 31;21(6):603-9. Epub 2015 Mar 31.

Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University School of Medicine, Sendai, Japan.

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http://dx.doi.org/10.1016/j.parkreldis.2015.03.020DOI Listing
June 2015

Roles and programming of Arabidopsis ARGONAUTE proteins during Turnip mosaic virus infection.

PLoS Pathog 2015 Mar 25;11(3):e1004755. Epub 2015 Mar 25.

Donald Danforth Plant Science Center, St. Louis, Missouri, United States of America; Center for Genome Research and Biocomputing, Department of Botany and Plant Pathology, Oregon State University, Corvallis, Oregon, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1004755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373807PMC
March 2015

[The Cutting-edge of Medicine; Pre-clinical diagnosis of neurodegenerative diseases].

Nihon Naika Gakkai Zasshi 2015 Feb;104(2):323-9

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http://dx.doi.org/10.2169/naika.104.323DOI Listing
February 2015

Olfactory dysfunction and dementia in Parkinson's disease.

J Parkinsons Dis 2014 ;4(2):181-7

Department of Behavioral Neurology and Cognitive Neuroscience, Seiryo-machi, Aoba-ku, Sendai, Japan.

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http://dx.doi.org/10.3233/JPD-130277DOI Listing
December 2014

Intracellular Zn(2+) signaling in the dentate gyrus is required for object recognition memory.

Hippocampus 2014 Nov 4;24(11):1404-12. Epub 2014 Jul 4.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan; Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

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http://dx.doi.org/10.1002/hipo.22322DOI Listing
November 2014

VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease.

Neurobiol Dis 2014 Nov 6;71:1-13. Epub 2014 Aug 6.

Division of Neurology, Department of Neuroscience & Sensory Organs, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.

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http://dx.doi.org/10.1016/j.nbd.2014.07.014DOI Listing
November 2014

Significance of Zn(2+) signaling in cognition: insight from synaptic Zn(2+) dyshomeostasis.

Authors:
Atsushi Takeda

J Trace Elem Med Biol 2014 Oct 5;28(4):393-6. Epub 2014 Jul 5.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jtemb.2014.06.021DOI Listing
October 2014

[Treatment & management guidelines 2011 for Parkinson disease].

Authors:
Atsushi Takeda

Rinsho Shinkeigaku 2013 ;53(11):1346-7

Division of Neurology, Department of Neuroscience & Sensory organs, Tohoku University Graduate School of Medicine.

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http://dx.doi.org/10.5692/clinicalneurol.53.1346DOI Listing
September 2014

Recovery of dicer-like 1-late flowering phenotype by miR172 expressed by the noncanonical DCL4-dependent biogenesis pathway.

RNA 2014 Aug 25;20(8):1320-7. Epub 2014 Jun 25.

Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Komaba 3-8-1, Meguro-ku, Tokyo 153-8902, Japan

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http://dx.doi.org/10.1261/rna.044966.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105755PMC
August 2014

Intracellular Zn(2+) signaling in cognition.

J Neurosci Res 2014 Jul 10;92(7):819-24. Epub 2014 Apr 10.

Department of Bioorganic Chemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan; Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.

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http://dx.doi.org/10.1002/jnr.23385DOI Listing
July 2014

The expression of relaxin-3 in adipose tissue and its effects on adipogenesis.

Protein Pept Lett 2014 Jun;21(6):517-22

Laboratory of Bioorganic Chemistry, School of Pharmaceutical Sciences, University of Shizuoka, 52- 1 Yada, Shizuoka 422-8526, Japan.

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http://dx.doi.org/10.2174/0929866520666131217101424DOI Listing
June 2014

Lys-63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized α-synuclein.

J Biol Chem 2014 Jun 15;289(26):18137-51. Epub 2014 May 15.

From the Division of Neurology, Department of Neuroscience and Sensory Organs, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.

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http://dx.doi.org/10.1074/jbc.M113.529461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140275PMC
June 2014

Enhanced susceptibility to spontaneous seizures of noda epileptic rats by loss of synaptic zn(2+).

PLoS One 2013 12;8(8):e71372. Epub 2013 Aug 12.

Department of Bioorganic chemistry, School of Pharmaceutical Sciences, University of Shizuoka, Global COE-21, 52- 1 Yada, Suruga-ku, Shizuoka, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0071372PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741169PMC
April 2014

Cognitive decline due to excess synaptic Zn(2+) signaling in the hippocampus.

Front Aging Neurosci 2014 27;6:26. Epub 2014 Feb 27.

Department of Bioorganic Chemistry, School of Pharmaceutical Sciences, University of Shizuoka Shizuoka, Japan.

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http://dx.doi.org/10.3389/fnagi.2014.00026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936311PMC
March 2014

[Dopaminergic drug-induced jaw-opening dystonia in a patient with progressive supranuclear palsy].

Rinsho Shinkeigaku 2013 ;53(4):308-11

Department of Neurology, Tohoku University School of Medicine.

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http://dx.doi.org/10.5692/clinicalneurol.53.308DOI Listing
February 2014

Improvement of freezing of gait in patients with Parkinson's disease by imagining bicycling.

Case Rep Neurol 2014 Jan 27;6(1):92-5. Epub 2014 Mar 27.

Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan.

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http://dx.doi.org/10.1159/000362119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995388PMC
January 2014

[Severe olfactory dysfunction is a predictor of dementia with Parkinson's disease].

Authors:
Atsushi Takeda

Rinsho Shinkeigaku 2013 ;53(2):91-7

Division of Neurology, Department of Neuroscience and Sensory Organs, Tohoku University Graduate School of Medicine.

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http://dx.doi.org/10.5692/clinicalneurol.53.91DOI Listing
December 2013

Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activity, trait anxiety and subjective stress.

Pharmacol Biochem Behav 2013 Oct 16;111:128-35. Epub 2013 Sep 16.

Laboratory of Bioorganic Chemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.pbb.2013.09.004DOI Listing
October 2013