Athanasios Typas

Athanasios Typas

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Athanasios Typas

Athanasios Typas

Publications by authors named "Athanasios Typas"

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43Publications

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A resource of variant effect predictions of single nucleotide variants in model organisms.

Mol Syst Biol 2018 12 20;14(12):e8430. Epub 2018 Dec 20.

European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301329PMC
http://dx.doi.org/10.15252/msb.20188430DOI Listing
December 2018

Thermal proteome profiling in bacteria: probing protein state .

Mol Syst Biol 2018 07 6;14(7):e8242. Epub 2018 Jul 6.

Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056769PMC
http://dx.doi.org/10.15252/msb.20188242DOI Listing
July 2018

Emerging and evolving concepts in gene essentiality.

Nat Rev Genet 2018 Jan 16;19(1):34-49. Epub 2017 Oct 16.

Singapore Immunology Network (SIgN), A*STAR, 8A Biomedical Grove, Immunos #04, Singapore 138648, Singapore.

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http://dx.doi.org/10.1038/nrg.2017.74DOI Listing
January 2018

Phenotype inference in an strain panel.

Elife 2017 12 27;6. Epub 2017 Dec 27.

European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, United Kingdom.

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http://dx.doi.org/10.7554/eLife.31035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745082PMC
December 2017

Systematically investigating the impact of medication on the gut microbiome.

Curr Opin Microbiol 2017 Oct;39:128-135

European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany; European Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.mib.2017.11.001DOI Listing
October 2017

Construction and Analysis of Two Genome-Scale Deletion Libraries for Bacillus subtilis.

Cell Syst 2017 03 8;4(3):291-305.e7. Epub 2017 Feb 8.

Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94158, USA; California Institute of Quantitative Biology, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2016.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400513PMC
March 2017

A tool named Iris for versatile high-throughput phenotyping in microorganisms.

Nat Microbiol 2017 Feb 17;2:17014. Epub 2017 Feb 17.

European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany.

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http://dx.doi.org/10.1038/nmicrobiol.2017.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464397PMC
February 2017

An atlas of human kinase regulation.

Mol Syst Biol 2016 Dec 1;12(12):888. Epub 2016 Dec 1.

European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199121PMC
http://dx.doi.org/10.15252/msb.20167295DOI Listing
December 2016

A Chemical-Genomic Screen of Neglected Antibiotics Reveals Illicit Transport of Kasugamycin and Blasticidin S.

PLoS Genet 2016 06 29;12(6):e1006124. Epub 2016 Jun 29.

Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927156PMC
June 2016

Integration of multi-omics data of a genome-reduced bacterium: Prevalence of post-transcriptional regulation and its correlation with protein abundances.

Nucleic Acids Res 2016 Feb 14;44(3):1192-202. Epub 2016 Jan 14.

European Molecular Biology Laboratory (EMBL) Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany Max-Delbrück-Centre (MDC) for Molecular Medicine, Robert-Rössle-Str. 10, 13092 Berlin, Germany

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http://dx.doi.org/10.1093/nar/gkw004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756857PMC
February 2016

Editorial overview: Microbial systems biology.

Curr Opin Microbiol 2015 Oct 20;27:viii-ix. Epub 2015 Oct 20.

European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.mib.2015.09.007DOI Listing
October 2015

Bacterial protein networks: properties and functions.

Nat Rev Microbiol 2015 Sep 10;13(9):559-72. Epub 2015 Aug 10.

Max Planck Institute for Terrestrial Microbiology and LOEWE Center for Synthetic Microbiology (SYNMIKRO), Karl-von-Frisch Strasse 16, 35043 Marburg, Germany.

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http://dx.doi.org/10.1038/nrmicro3508DOI Listing
September 2015

Detecting envelope stress by monitoring β-barrel assembly.

Cell 2014 Dec;159(7):1652-64

WELBIO, Université catholique de Louvain, Avenue Hippocrate 75, Brussels 1200, Belgium; de Duve Institute, Université catholique de Louvain, Avenue Hippocrate 75, Brussels 1200, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.11.045DOI Listing
December 2014

Outer-membrane lipoprotein LpoB spans the periplasm to stimulate the peptidoglycan synthase PBP1B.

Proc Natl Acad Sci U S A 2014 Jun 12;111(22):8197-202. Epub 2014 May 12.

Institut de Biologie Structurale, Université Grenoble Alpes, F-38027 Grenoble, France;Institut de Biologie Structurale, Direction des Sciences du Vivant, Commissariat à l'Energie Atomique, F-38027 Grenoble, France;Institut de Biologie Structurale, Centre National de la Recherche Scientifique, F-38027 Grenoble, France;

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http://dx.doi.org/10.1073/pnas.1400376111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050580PMC
June 2014

Dynamic protein complexes for cell growth.

Proc Natl Acad Sci U S A 2014 Mar 17;111(12):4355-6. Epub 2014 Mar 17.

European Molecular Biology Laboratory, Genome Biology Unit, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1073/pnas.1402016111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970523PMC
March 2014

A genome-wide screen for bacterial envelope biogenesis mutants identifies a novel factor involved in cell wall precursor metabolism.

PLoS Genet 2014 Jan 2;10(1):e1004056. Epub 2014 Jan 2.

Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879167PMC
January 2014

Fe-S cluster biosynthesis controls uptake of aminoglycosides in a ROS-less death pathway.

Science 2013 Jun;340(6140):1583-7

Laboratoire de Chimie Bactérienne, Aix-Marseille Université, CNRS, UMR 7283, Institut de Microbiologie de la Méditerranée, 31 Chemin Joseph Aiguier, 13009 Marseille France.

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http://dx.doi.org/10.1126/science.1238328DOI Listing
June 2013

High-throughput approaches to understanding gene function and mapping network architecture in bacteria.

Curr Opin Microbiol 2013 Apr 9;16(2):199-206. Epub 2013 Feb 9.

Genome Biology Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, Heidelberg 69117, Germany.

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http://dx.doi.org/10.1016/j.mib.2013.01.008DOI Listing
April 2013

From the regulation of peptidoglycan synthesis to bacterial growth and morphology.

Nat Rev Microbiol 2011 Dec 28;10(2):123-36. Epub 2011 Dec 28.

Department of Microbiology & Immunology, University of California, San Francisco, USA.

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http://dx.doi.org/10.1038/nrmicro2677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433867PMC
December 2011

Escherichia coli σ⁷⁰ senses sequence and conformation of the promoter spacer region.

Nucleic Acids Res 2011 Jul 11;39(12):5109-18. Epub 2011 Mar 11.

School of Life Sciences, The University of Warwick, Coventry CV4 7AL, UK.

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http://dx.doi.org/10.1093/nar/gkr080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130263PMC
July 2011

High-throughput, quantitative analyses of genetic interactions in E. coli.

Nat Methods 2008 Sep;5(9):781-7

Department of Microbiology and Immunology, University of California at San Francisco, 600 16th Street, San Francisco, California 94158, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700713PMC
September 2008

The molecular basis of selective promoter activation by the sigmaS subunit of RNA polymerase.

Mol Microbiol 2007 Mar;63(5):1296-306

Institut für Biologie, Mikrobiologie, Freie Universität Berlin, Königin-Luise-Str. 12-16, 14195 Berlin, Germany.

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http://doi.wiley.com/10.1111/j.1365-2958.2007.05601.x
Publisher Site
http://dx.doi.org/10.1111/j.1365-2958.2007.05601.xDOI Listing
March 2007

The -35 sequence location and the Fis-sigma factor interface determine sigmas selectivity of the proP (P2) promoter in Escherichia coli.

Mol Microbiol 2007 Feb;63(3):780-96

Institut für Biologie, Mikrobiologie, Freie Universität Berlin, Königin-Luise-Str. 12-16, 14195 Berlin, Germany.

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http://dx.doi.org/10.1111/j.1365-2958.2006.05560.xDOI Listing
February 2007

Role of the spacer between the -35 and -10 regions in sigmas promoter selectivity in Escherichia coli.

Mol Microbiol 2006 Feb;59(3):1037-51

Institut für Biologie, Mikrobiologie, Freie Universität Berlin, Königin-Luise-Str. 12-16, 14195 Berlin, Germany.

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http://dx.doi.org/10.1111/j.1365-2958.2005.04998.xDOI Listing
February 2006

Differential ability of sigma(s) and sigma70 of Escherichia coli to utilize promoters containing half or full UP-element sites.

Mol Microbiol 2005 Jan;55(1):250-60

Institut für Biologie-Mikrobiologie, Freie Universität Berlin, Königin-Luise-Str 12-16, 14195 Berlin, Germany.

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http://doi.wiley.com/10.1111/j.1365-2958.2004.04382.x
Publisher Site
http://dx.doi.org/10.1111/j.1365-2958.2004.04382.xDOI Listing
January 2005