Publications by authors named "Aswin Chandran"

11 Publications

  • Page 1 of 1

Outcomes of Ttracheostomy in COVID-19 Patients: A Single Centre Experience.

Indian J Otolaryngol Head Neck Surg 2021 Jul 13:1-7. Epub 2021 Jul 13.

Department of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, 110029 India.

The rapid emergence of COVID-19 has led to increase in the number of patients requiring prolonged ventilation and tracheostomy. Though global guidelines are evolving, there is a paucity of literature about optimal timing and outcome after tracheostomy in COVID-19 patients. We set out to assess the clinical characteristics and outcome of COVID-19 patients who underwent tracheostomy.This single-center, prospective observational cohort study analyzed all the consecutive tracheostomy performed on COVID-19 patients from April 1 2020 to January 31, 2021. The primary outcome measure was the 30-day mortality rate following tracheostomy and association with various prognostic risk factors. The secondary outcome measures included various tracheostomy-related events, perioperative complications, and decannulation rate.The study included 51 patients with a median age of 52 years and the majority were male (62.74%). 62.74% (32 of 51) tracheostomies were done early (within 10 days of intubation) and the mean duration from endotracheal intubation to tracheostomy was 10.27 days. The 30-day mortality rate was 66.66% (34 of 51) with no tracheostomy-related mortality and the mean duration between tracheostomy and death was 8.29 days. The presence of sepsis was associated with a higher rate of mortality ( = 0.002) while the timing of tracheostomy was not related to increased mortality ( = 0.365). The most common perioperative complication was tracheostoma bleeding (16.64%). At a median follow-up of 7.5 months, only four patients were decannulated.Though associated with a higher rate of 30-day mortality rate, tracheostomy among COVID-19 patients is a safe and an effective weaning tool.
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http://dx.doi.org/10.1007/s12070-021-02758-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276681PMC
July 2021

Rhino-orbital mucormycosis in a COVID-19 patient.

BMJ Case Rep 2021 06 24;14(6). Epub 2021 Jun 24.

Department of Otorhinolaryngology & Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1136/bcr-2021-244232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230977PMC
June 2021

Sinonasal polyposis complicated with extradural abscess and lateral rectus palsy.

BMJ Case Rep 2021 May 26;14(5). Epub 2021 May 26.

ENT & Head and neck surgery, All India Institute of Medical Sciences, New Delhi, India.

Sinogenic intracranial and orbital complications are infrequent complications of chronic rhinosinusitis with nasal polyposis (CRSwNP), leading to potentially fatal intracranial and orbital sequelae. The mortality and morbidity associated with these complications remain high despite the widespread use of antibiotics. We report a patient with CRSwNP presenting with acute onset extradural empyema and sixth nerve palsy in whom the diagnosis was delayed, necessitating early surgical intervention. Our case shows that delay in management and underdiagnosis of sinusitis with nasal polyposis can lead to devastating complications. A high index of suspicion, early recognition of the clinical findings and radiological evaluation with contrast-enhanced CT of paranasal sinuses, orbit and brain are essential to rule out fatal complications associated with CRSwNP. Timely endoscopic intervention and the use of antibiotics can lead to good outcomes, even in complicated cases.
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http://dx.doi.org/10.1136/bcr-2021-242667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160177PMC
May 2021

Mounier-Kuhn syndrome.

BMJ Case Rep 2021 Jan 28;14(1). Epub 2021 Jan 28.

Otorhinolaryngology & Head Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1136/bcr-2020-239876DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7845718PMC
January 2021

Emergency Tracheostomy Amid COVID-19.

Otolaryngol Head Neck Surg 2021 07 12;165(1):234-235. Epub 2021 Jan 12.

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http://dx.doi.org/10.1177/0194599820986568DOI Listing
July 2021

Erection of pinna.

BMJ Case Rep 2020 Dec 22;13(12). Epub 2020 Dec 22.

Otorhinolaryngology & Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, India

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http://dx.doi.org/10.1136/bcr-2020-239745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757462PMC
December 2020

Iatrogenic extracranial internal carotid artery aneurysm.

Postgrad Med J 2020 Nov 12. Epub 2020 Nov 12.

Otorhinolaryngology & Head- Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1136/postgradmedj-2020-139162DOI Listing
November 2020

Unusual manifestation of Koch's disease: Gradenigo-Lannois syndrome.

BMJ Case Rep 2020 Nov 2;13(11). Epub 2020 Nov 2.

Otorhinolaryngology & Head Neck Surgery, All India Institute of Medical Sciences, New Delhi, Delhi, India.

Gradenigo-Lannois syndrome or petrous apicitis is an uncommon but a morbid complication of otitis media. Traditionally treated by surgery, recent advances in imaging and antibiotics have favoured a more conservative approach. Although pyogenic organisms are the leading aetiological agent, petrous apicitis due to Koch's bacilli is not rare. We report two cases of tubercular petrositis presenting as Gradenigo's syndrome with triad of ear discharge, deep-seated retro-orbital pain and diplopia. The first patient represented a mixed infection with pyogenic organism and tuberculosis, which was successfully treated with antibiotics and antitubercular therapy. The second patient showed an acute presentation of Gradenigo's syndrome with chronic otitis media having contact with an active tuberculosis case and showed dramatic response with antitubercular treatment. Tubercular petrous apicitis must be suspected and diagnosed promptly as only specific treatment will lead to symptomatic resolution and avoid complications.
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http://dx.doi.org/10.1136/bcr-2020-236779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607578PMC
November 2020

An Unusual Cause of Dysphagia.

Dysphagia 2020 Sep 2. Epub 2020 Sep 2.

Department of Otorhinolaryngology & Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, 110029, India.

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http://dx.doi.org/10.1007/s00455-020-10186-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466928PMC
September 2020

Addressing a rare cause of paediatric stridor: subglottic cyst.

BMJ Case Rep 2020 Jun 28;13(6). Epub 2020 Jun 28.

Department of Otorhinolaryngology and Head Neck Surgery, All India Institute of Medical Sciences, New Delhi, Delhi, India.

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http://dx.doi.org/10.1136/bcr-2020-236600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322319PMC
June 2020

Pharyngeal rhinosporidiosis.

BMJ Case Rep 2020 Jun 17;13(6). Epub 2020 Jun 17.

Pathology, All India Institute of Medical Sciences, New Delhi, Delhi, India.

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http://dx.doi.org/10.1136/bcr-2020-236404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304642PMC
June 2020