Astrid Sydow

Astrid Sydow

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Astrid Sydow

Astrid Sydow

Publications by authors named "Astrid Sydow"

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Functional networks are impaired by elevated tau-protein but reversible in a regulatable Alzheimer's disease mouse model.

Mol Neurodegener 2019 03 27;14(1):13. Epub 2019 Mar 27.

In-vivo-NMR Laboratory, Max Planck Institute for Metabolism Research, Gleuelerstrasse 50, D-50931, Cologne, Germany.

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http://dx.doi.org/10.1186/s13024-019-0316-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438042PMC
March 2019

Adenosine A1 receptor antagonist rolofylline alleviates axonopathy caused by human Tau ΔK280.

Proc Natl Acad Sci U S A 2016 10 26;113(41):11597-11602. Epub 2016 Sep 26.

German Center for Neurodegenerative Diseases, 53127 Bonn, Germany; Center of Advanced European Studies and Research, 53175 Bonn, Germany; Max Planck Institute for Metabolism Research, 22607 Hamburg, Germany

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http://dx.doi.org/10.1073/pnas.1603119113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068267PMC
October 2016

The Tau/A152T mutation, a risk factor for frontotemporal-spectrum disorders, leads to NR2B receptor-mediated excitotoxicity.

EMBO Rep 2016 04 1;17(4):552-69. Epub 2016 Mar 1.

German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany Max-Planck-Institute for Metabolism Research (Cologne), Hamburg Outstation, Hamburg, Germany Caesar Research Center, Bonn, Germany

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http://dx.doi.org/10.15252/embr.201541439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818782PMC
April 2016

Regulatable transgenic mouse models of Alzheimer disease: onset, reversibility and spreading of Tau pathology.

FEBS J 2013 Sep 22;280(18):4371-81. Epub 2013 Apr 22.

Deutsches Zentrum für Neurodegenerative Erkrankungen, Bonn, Germany.

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http://dx.doi.org/10.1111/febs.12250DOI Listing
September 2013

Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau.

Acta Neuropathol 2012 Jun 25;123(6):787-805. Epub 2012 Apr 25.

DZNE (German Center for Neurodegenerative Diseases) and CAESAR Research Center, Ludwig-Erhard-Allee 2, 53175 Bonn, Germany.

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http://link.springer.com/10.1007/s00401-012-0987-3
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http://dx.doi.org/10.1007/s00401-012-0987-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979687PMC
June 2012

'Prion-like' propagation of mouse and human tau aggregates in an inducible mouse model of tauopathy.

Neurodegener Dis 2010 13;7(1-3):28-31. Epub 2010 Feb 13.

Max-Planck-Unit for Structural Molecular Biology, Hamburg, Germany.

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http://dx.doi.org/10.1159/000283479DOI Listing
July 2010