Asrar B Malik

Asrar B Malik

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Asrar B Malik

Publications by authors named "Asrar B Malik"

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Septin2 mediates podosome maturation and endothelial cell invasion associated with angiogenesis.

J Cell Biol 2020 Feb;219(2)

Department of Pharmacology, University of Illinois College of Medicine, Chicago, IL.

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http://dx.doi.org/10.1083/jcb.201903023DOI Listing
February 2020

Comprehensive transcriptomic profiling reveals SOX7 as an early regulator of angiogenesis in hypoxic human endothelial cells.

J Biol Chem 2020 Feb 18. Epub 2020 Feb 18.

Pharmacology, University of Illinois at Chicago, United States.

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http://dx.doi.org/10.1074/jbc.RA119.011822DOI Listing
February 2020

Caspase-11 Mediates Pyroptosis of Tubular Epithelial Cells and Septic Acute Kidney Injury.

Kidney Blood Press Res 2019 21;44(4):465-478. Epub 2019 Jun 21.

Division of Nephrology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China,

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http://dx.doi.org/10.1159/000499685DOI Listing
January 2020

Endothelial heterogeneity across distinct vascular beds during homeostasis and inflammation.

Elife 2020 Jan 16;9. Epub 2020 Jan 16.

Department of Pharmacology, The University of Illinois College of Medicine, Chicago, United States.

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http://dx.doi.org/10.7554/eLife.51413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002042PMC
January 2020

Time-Variant SRC Kinase Activation Determines Endothelial Permeability Response.

Cell Chem Biol 2019 Aug 23;26(8):1081-1094.e6. Epub 2019 May 23.

Department of Pharmacology, The University of Illinois College of Medicine, 835 S. Wolcott Avenue, Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2019.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697609PMC
August 2019

STAT6 induces expression of Gas6 in macrophages to clear apoptotic neutrophils and resolve inflammation.

Proc Natl Acad Sci U S A 2019 Aug 30;116(33):16513-16518. Epub 2019 Jul 30.

Department of Pharmacology, University of Illinois College of Medicine, Chicago, IL 60612;

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http://dx.doi.org/10.1073/pnas.1821601116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697797PMC
August 2019

Endothelial cell Piezo1 mediates pressure-induced lung vascular hyperpermeability via disruption of adherens junctions.

Proc Natl Acad Sci U S A 2019 Jun 11;116(26):12980-12985. Epub 2019 Jun 11.

Department of Pharmacology, University of Illinois College of Medicine, University of Illinois at Chicago, Chicago, IL 60612;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1902165116
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http://dx.doi.org/10.1073/pnas.1902165116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600969PMC
June 2019

VE-PTP stabilizes VE-cadherin junctions and the endothelial barrier via a phosphatase-independent mechanism.

J Cell Biol 2019 May 4;218(5):1725-1742. Epub 2019 Apr 4.

Department of Pharmacology and the Center for Lung and Vascular Biology, The University of Illinois College of Medicine, Chicago, IL

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http://dx.doi.org/10.1083/jcb.201807210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504901PMC
May 2019

Sox17 is required for endothelial regeneration following inflammation-induced vascular injury.

Nat Commun 2019 05 9;10(1):2126. Epub 2019 May 9.

Department of Pharmacology, The University of Illinois College of Medicine, Chicago, IL, 60612, USA.

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http://dx.doi.org/10.1038/s41467-019-10134-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509327PMC
May 2019

Dlk1-Mediated Temporal Regulation of Notch Signaling Is Required for Differentiation of Alveolar Type II to Type I Cells during Repair.

Cell Rep 2019 03;26(11):2942-2954.e5

Department of Pharmacology, The University of Illinois College of Medicine, Chicago, IL 60612, USA; The Center for Lung and Vascular Biology, The University of Illinois College of Medicine, Chicago, IL 60612, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247193021
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http://dx.doi.org/10.1016/j.celrep.2019.02.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464111PMC
March 2019

Piezo1 mediates angiogenesis through activation of MT1-MMP signaling.

Am J Physiol Cell Physiol 2019 01 14;316(1):C92-C103. Epub 2018 Nov 14.

Department of Pharmacology and The Center for Lung and Vascular Biology, The University of Illinois College of Medicine , Chicago, Illinois.

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http://dx.doi.org/10.1152/ajpcell.00346.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383143PMC
January 2019

The TWIK2 Potassium Efflux Channel in Macrophages Mediates NLRP3 Inflammasome-Induced Inflammation.

Immunity 2018 07 26;49(1):56-65.e4. Epub 2018 Jun 26.

Department of Pharmacology and the Center for Lung and Vascular Biology, The University of Illinois College of Medicine, Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.04.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051907PMC
July 2018

A computational approach to identify cellular heterogeneity and tissue-specific gene regulatory networks.

BMC Bioinformatics 2018 06 7;19(1):217. Epub 2018 Jun 7.

Department of Pharmacology, The University of Illinois College of Medicine, 835 S. Wolcott Ave. Rm. E403, Chicago, IL, 60612, USA.

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http://dx.doi.org/10.1186/s12859-018-2190-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019795PMC
June 2018

Mechanosensing Piezo channels in tissue homeostasis including their role in lungs.

Pulm Circ 2018 Apr-Jun;8(2):2045894018767393. Epub 2018 Mar 9.

Department of Pharmacology and Center of Lung and Vascular Biology, University of Illinois, College of Medicine, Chicago, IL, USA.

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http://dx.doi.org/10.1177/2045894018767393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024292PMC
March 2018

Response by Mittal et al to Letter Regarding Article, "Neutrophil Activation of Endothelial Cell-Expressed TRPM2 Mediates Transendothelial Neutrophil Migration and Vascular Injury".

Circ Res 2017 12;121(12):e87

Department of Pharmacology, The Center for Lung and Vascular Biology, The University of Illinois College of Medicine, Chicago, IL, Department of Medicine, The University of Illinois College of Medicine, Chicago, IL.

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http://dx.doi.org/10.1161/CIRCRESAHA.117.312146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757838PMC
December 2017

Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury.

J Clin Invest 2017 Nov 9;127(11):4124-4135. Epub 2017 Oct 9.

Department of Pharmacology, The University of Illinois College of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1172/JCI94495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663346PMC
November 2017

Neutrophil Activation of Endothelial Cell-Expressed TRPM2 Mediates Transendothelial Neutrophil Migration and Vascular Injury.

Circ Res 2017 Oct 8;121(9):1081-1091. Epub 2017 Aug 8.

From the Department of Pharmacology (M.M., S.N., Y.T., C.M.H., D.S., J.L., C.T., A.B.M.), and Department of Medicine, University of Illinois College of Medicine (J.L.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.311747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640489PMC
October 2017

Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1α.

Stem Cell Reports 2017 09 3;9(3):796-806. Epub 2017 Aug 3.

Department of Pharmacology and the Center for Lung and Vascular Biology, University of Illinois College of Medicine, 835 S. Wolcott, Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599266PMC
September 2017

SOX17 Regulates Conversion of Human Fibroblasts Into Endothelial Cells and Erythroblasts by Dedifferentiation Into CD34 Progenitor Cells.

Circulation 2017 Jun 5;135(25):2505-2523. Epub 2017 Apr 5.

From Department of Pharmacology (L.Z., A.J., Z.H., G.M., P.T.T., A.B.M., J.R.), Department of Medicine, Division of Cardiology (J.R.), The University of Illinois College of Medicine, Chicago; and Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis (B.-S.H.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.025722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472005PMC
June 2017

Pyk2 phosphorylation of VE-PTP downstream of STIM1-induced Ca entry regulates disassembly of adherens junctions.

Am J Physiol Lung Cell Mol Physiol 2017 06 6;312(6):L1003-L1017. Epub 2017 Apr 6.

Department of Pharmacology and Center for Lung and Vascular Biology, College of Medicine, University of Illinois, Chicago, Illinois

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http://dx.doi.org/10.1152/ajplung.00008.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495943PMC
June 2017

Response by Komarova et al to Letter Regarding Article, "Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability".

Circ Res 2017 03;120(5):e28

Department of Pharmacology and the Center for Lung and Vascular Biology, University of Illinois College of Medicine, Chicago.

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http://dx.doi.org/10.1161/CIRCRESAHA.117.310647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460369PMC
March 2017

Inactivation of Rab11a GTPase in Macrophages Facilitates Phagocytosis of Apoptotic Neutrophils.

J Immunol 2017 02 4;198(4):1660-1672. Epub 2017 Jan 4.

Department of Anesthesiology, University of Illinois College of Medicine, Chicago, IL 60612;

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http://dx.doi.org/10.4049/jimmunol.1601495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296368PMC
February 2017

Role of the phagosomal redox-sensitive TRP channel TRPM2 in regulating bactericidal activity of macrophages.

J Cell Sci 2017 02 12;130(4):735-744. Epub 2017 Jan 12.

Department of Pharmacology and the Center for Lung and Vascular Biology, The University of Illinois College of Medicine, Chicago, IL 60612, USA

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http://dx.doi.org/10.1242/jcs.196014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339887PMC
February 2017

Method for Dual Viral Vector Mediated CRISPR-Cas9 Gene Disruption in Primary Human Endothelial Cells.

Sci Rep 2017 02 15;7:42127. Epub 2017 Feb 15.

Department of Pharmacology, University of Illinois College of Medicine, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1038/srep42127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309830PMC
February 2017

Antiangiogenic Therapeutic Potential of Peptides Derived from the Molecular Motor KIF13B that Transports VEGFR2 to Plasmalemma in Endothelial Cells.

Am J Pathol 2017 01 15;187(1):214-224. Epub 2016 Nov 15.

Department of Pharmacology, The University of Illinois College of Medicine, Chicago, Illinois; Center of Lung and Vascular Biology, The University of Illinois College of Medicine, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2016.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225310PMC
January 2017

Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability.

Circ Res 2017 Jan;120(1):179-206

From the Department of Pharmacology and the Center for Lung and Vascular Biology, University of Illinois College of Medicine, Chicago.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.306534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225667PMC
January 2017

PAR1 Scaffolds TGFβRII to Downregulate TGF-β Signaling and Activate ESC Differentiation to Endothelial Cells.

Stem Cell Reports 2016 12 17;7(6):1050-1058. Epub 2016 Nov 17.

Department of Pharmacology, University of Illinois, College of Medicine, 835 South Wolcott Avenue, Room E403, Chicago, IL 60612, USA; The Center for Lung and Vascular Biology, University of Illinois, College of Medicine, 835 South Wolcott Avenue, Room E403, Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2016.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161529PMC
December 2016

TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury.

Proc Natl Acad Sci U S A 2016 12 28;113(50):E8151-E8158. Epub 2016 Nov 28.

Department of Pharmacology and Center for Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL 60612

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http://dx.doi.org/10.1073/pnas.1614935113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167170PMC
December 2016

Mimicking transient activation of protein kinases in living cells.

Proc Natl Acad Sci U S A 2016 12 12;113(52):14976-14981. Epub 2016 Dec 12.

Department of Pharmacology, University of Illinois, Chicago, IL 60612

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http://dx.doi.org/10.1073/pnas.1609675114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206511PMC
December 2016

Induced Pluripotent Stem (iPS) Cell Culture Methods and Induction of Differentiation into Endothelial Cells.

Methods Mol Biol 2016 ;1357:311-27

Department of Pharmacology, University of Illinois at Chicago, 835 S. Wolcott Ave., Chicago, IL, 60612, USA.

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http://dx.doi.org/10.1007/7651_2015_203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539286PMC
October 2016

ROS-activated calcium signaling mechanisms regulating endothelial barrier function.

Cell Calcium 2016 09 17;60(3):163-71. Epub 2016 Feb 17.

Department of Pharmacology, The University of Illinois College of Medicine, Chicago, IL 60612, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ceca.2016.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988951PMC
September 2016

Oxidant Sensing by TRPM2 Inhibits Neutrophil Migration and Mitigates Inflammation.

Dev Cell 2016 09 25;38(5):453-62. Epub 2016 Aug 25.

Department of Pharmacology, University of Illinois, Chicago, IL 60612, USA; Department of Neurosurgery, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15345807163050
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http://dx.doi.org/10.1016/j.devcel.2016.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455786PMC
September 2016

Using cultured endothelial cells to study endothelial barrier dysfunction: Challenges and opportunities.

Am J Physiol Lung Cell Mol Physiol 2016 08 24;311(2):L453-66. Epub 2016 Jun 24.

Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands;

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http://dx.doi.org/10.1152/ajplung.00393.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504427PMC
August 2016

Src-dependent phosphorylation of caveolin-1 Tyr-14 promotes swelling and release of caveolae.

Mol Biol Cell 2016 07 11;27(13):2090-106. Epub 2016 May 11.

Department of Pharmacology, University of Illinois at Chicago, Chicago, IL 60612 Department of Anesthesiology, University of Illinois at Chicago, Chicago, IL 60612 Center for Lung and Vascular Biology, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612

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http://dx.doi.org/10.1091/mbc.E15-11-0756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927282PMC
July 2016

Glutamine Metabolism Regulates the Pluripotency Transcription Factor OCT4.

Cell Rep 2016 07 23;16(2):323-332. Epub 2016 Jun 23.

Department of Pharmacology, University of Illinois College of Medicine, Chicago, IL 60612, USA; Division of Cardiology, Department of Medicine, University of Illinois College of Medicine, Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.05.089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945388PMC
July 2016

Endothelial p110γPI3K Mediates Endothelial Regeneration and Vascular Repair After Inflammatory Vascular Injury.

Circulation 2016 Mar 2;133(11):1093-103. Epub 2016 Feb 2.

From Department of Pharmacology (X.H., Z.D., L.C., K.S., J.C., A.B.M., Y.-Y.Z.), Center for Lung and Vascular Biology (X.H., Z.D., L.C., K.S., A.B.M., Y.-Y.Z.), Department of Medicine (D.E.S.), University of Illinois College of Medicine, Chicago; and Departments of Pediatrics and Medicine, University of Utah School of Medicine, Salt Lake City (K.H.A.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.020918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792690PMC
March 2016

Rab11a Mediates Vascular Endothelial-Cadherin Recycling and Controls Endothelial Barrier Function.

Arterioscler Thromb Vasc Biol 2016 Feb 10;36(2):339-49. Epub 2015 Dec 10.

From the Departments of Anesthesiology (Z.Y., Z.-G.W., R.D.M., R.O.D., M.Z., G.H.), Pharmacology (Z.Y., R.D.M., A.B.M., G.H.), and Biochemistry and Molecular Genetics (N.S.), University of Illinois College of Medicine, Chicago; and Department of General Surgery, Qilu Hospital of Shandong University, Jinan, China (Z.Y., S.H.).

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http://dx.doi.org/10.1161/ATVBAHA.115.306549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732894PMC
February 2016

Endothelial β-Catenin Signaling Is Required for Maintaining Adult Blood-Brain Barrier Integrity and Central Nervous System Homeostasis.

Circulation 2016 Jan 4;133(2):177-86. Epub 2015 Nov 4.

From Department of Pharmacology (K.A.T., X.Z., X.H., A.B.M., Y.Y.Z), Center for Lung and Vascular Biology (K.A.T., X.Z., X.H., A.B.M., Y.Y.Z), Department of Medicine (R.F.M.), and Department of Pathology (T.V.-N.), University of Illinois College of Medicine, Chicago; Department of Pharmacology, Rush University, Chicago, IL (D.P.); and Department of Hematology, West German Cancer Center, University Hospital Essen, Essen, Germany (J.R.G.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.015982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814374PMC
January 2016

NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1.

J Exp Med 2015 Sep 31;212(10):1725-38. Epub 2015 Aug 31.

Department of Medicine, Department of Pharmacology, Department of Anesthesiology, and Department of Pathology, University of Illinois College of Medicine, Chicago, IL 60607 Department of Medicine, Department of Pharmacology, Department of Anesthesiology, and Department of Pathology, University of Illinois College of Medicine, Chicago, IL 60607 Department of Anatomy and Cell Biology, Stark Neurosciences Research Institute, Indiana University, Indianapolis, IN 46202

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http://dx.doi.org/10.1084/jem.20140654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577833PMC
September 2015

Microtubule-Associated Protein EB3 Regulates IP3 Receptor Clustering and Ca(2+) Signaling in Endothelial Cells.

Cell Rep 2015 Jul 25;12(1):79-89. Epub 2015 Jun 25.

Department of Pharmacology and The Center for Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487770PMC
July 2015

Histone Demethylases KDM4A and KDM4C Regulate Differentiation of Embryonic Stem Cells to Endothelial Cells.

Stem Cell Reports 2015 Jul 25;5(1):10-21. Epub 2015 Jun 25.

Department of Pharmacology, University of Illinois College of Medicine, Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2015.05.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618442PMC
July 2015

Integrin α6β1 Expressed in ESCs Instructs the Differentiation to Endothelial Cells.

Stem Cells 2015 Jun;33(6):1719-29

Department of Pharmacology, University of Illinois College of Medicine, Chicago, Illinois, USA.

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http://doi.wiley.com/10.1002/stem.1974
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http://dx.doi.org/10.1002/stem.1974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441581PMC
June 2015

p120-catenin expressed in alveolar type II cells is essential for the regulation of lung innate immune response.

Am J Pathol 2015 May 13;185(5):1251-63. Epub 2015 Mar 13.

Department of Pharmacology, University of Illinois College of Medicine, Chicago, Illinois; University of Illinois Cancer Center, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2015.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419206PMC
May 2015

Novel role of reactive oxygen species-activated Trp melastatin channel-2 in mediating angiogenesis and postischemic neovascularization.

Arterioscler Thromb Vasc Biol 2015 Apr 12;35(4):877-87. Epub 2015 Feb 12.

From the Department of Pharmacology, Center for Lung and Vascular Biology, University of Illinois College of Medicine, Chicago.

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http://dx.doi.org/10.1161/ATVBAHA.114.304802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396825PMC
April 2015

S1PR1 Tyr143 phosphorylation downregulates endothelial cell surface S1PR1 expression and responsiveness.

J Cell Sci 2015 Mar 14;128(5):878-87. Epub 2015 Jan 14.

Department of Pharmacology and Center for Lung and Vascular Biology, The University of Illinois College of Medicine, Chicago, IL 60612, USA

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http://dx.doi.org/10.1242/jcs.154476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342577PMC
March 2015

Microfluidic platform generates oxygen landscapes for localized hypoxic activation.

Lab Chip 2014 Dec 15;14(24):4688-95. Epub 2014 Oct 15.

Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.

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http://dx.doi.org/10.1039/c4lc01168fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229417PMC
December 2014

Therapeutic administration of the chemokine CXCL1/KC abrogates autoimmune inflammatory heart disease.

PLoS One 2014 27;9(2):e89647. Epub 2014 Feb 27.

Department of Pharmacology, College of Medicine, University of Illinois at Chicago, Center for Lung and Vascular Biology, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0089647PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937330PMC
October 2014

KIF13B regulates angiogenesis through Golgi to plasma membrane trafficking of VEGFR2.

J Cell Sci 2014 Oct 15;127(Pt 20):4518-30. Epub 2014 Aug 15.

Department of Pharmacology, University of Illinois College of Medicine, Chicago, IL 60612, USA Center of Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, IL 60612, USA

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http://jcs.biologists.org/content/joces/127/20/4518.full.pdf
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http://jcs.biologists.org/cgi/doi/10.1242/jcs.156109
Publisher Site
http://dx.doi.org/10.1242/jcs.156109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197089PMC
October 2014

Pseudomonas aeruginosa induced lung injury model.

J Vis Exp 2014 Oct 29(92):e52044. Epub 2014 Oct 29.

Department of Pharmacology, University of Illinois College of Medicine, University of Illinois at Chicago;

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http://dx.doi.org/10.3791/52044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330790PMC
October 2014

Reprogramming fibroblasts to endothelial cells: converted or born again?

Circulation 2014 Sep 3;130(14):1136-8. Epub 2014 Sep 3.

From the Section of Cardiology, Department of Medicine ( L.Z., J.R.), and Department of Pharmacology (L.Z., A.B.M., J.R.), University of Illinois at Chicago, College of Medicine, Chicago.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.012540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182144PMC
September 2014

Bioenergetic shifts during transitions between stem cell states (2013 Grover Conference series).

Pulm Circ 2014 Sep;4(3):387-94

Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois, USA ; Section of Cardiology, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1086/677353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278598PMC
September 2014

Regulating the regulator of ROS production.

Cell Res 2014 Aug 20;24(8):908-9. Epub 2014 May 20.

1] Department of Pharmacology, The University of Illinois College of Medicine, 835 South Wolcott Avenue, Chicago, IL 60612, USA [2] Center for Lung and Vascular Biology, The University of Illinois College of Medicine, 835 South Wolcott Avenue, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1038/cr.2014.66DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123290PMC
August 2014

Combinatorial therapy with acetylation and methylation modifiers attenuates lung vascular hyperpermeability in endotoxemia-induced mouse inflammatory lung injury.

Am J Pathol 2014 Aug 12;184(8):2237-49. Epub 2014 Jun 12.

Division of Cardiovascular Diseases, Department of Internal Medicine, Cardiovascular Research Institute, University of Kansas Medical Center, Kansas City, Kansas; Department of Biochemistry and Molecular Biology, Cardiovascular Research Institute, University of Kansas Medical Center, Kansas City, Kansas. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2014.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116699PMC
August 2014

Differential role for p120-catenin in regulation of TLR4 signaling in macrophages.

J Immunol 2014 Aug 11;193(4):1931-41. Epub 2014 Jul 11.

Department of Anesthesiology, University of Illinois College of Medicine, Chicago, IL 60612; Department of Pharmacology, University of Illinois College of Medicine, Chicago, IL 60612

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http://www.jimmunol.org/content/early/2014/07/11/jimmunol.13
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1302863
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http://dx.doi.org/10.4049/jimmunol.1302863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119481PMC
August 2014

Cooperative signaling via transcription factors NF-κB and AP1/c-Fos mediates endothelial cell STIM1 expression and hyperpermeability in response to endotoxin.

J Biol Chem 2014 Aug 11;289(35):24188-201. Epub 2014 Jul 11.

From the Department of Pharmacology and Center for Lung and Vascular Biology, College of Medicine, University of Illinois, Chicago, Illinois 60612

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http://dx.doi.org/10.1074/jbc.M114.570051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148850PMC
August 2014

Endothelial progenitor cells and vascular repair.

Curr Opin Hematol 2014 May;21(3):224-8

aDepartment of Pharmacology bCenter for Lung and Vascular Biology cDepartment of Medicine, Section of Cardiology, University of Illinois, Chicago, Illinois, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MOH.0000000000000041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090051PMC
May 2014

Reactive oxygen species in inflammation and tissue injury.

Antioxid Redox Signal 2014 Mar 22;20(7):1126-67. Epub 2013 Oct 22.

1 Department of Pharmacology, Center for Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, Illinois.

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http://www.liebertpub.com/doi/10.1089/ars.2012.5149
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http://dx.doi.org/10.1089/ars.2012.5149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929010PMC
March 2014

Prevention of vascular inflammation by nanoparticle targeting of adherent neutrophils.

Nat Nanotechnol 2014 Mar 23;9(3):204-10. Epub 2014 Feb 23.

1] Department of Pharmacology, University of Illinois Chicago College of Medicine, Chicago, Illinois 60612, USA [2] Center for Lung and Vascular Biology, University of Illinois Chicago College of Medicine, Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1038/nnano.2014.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100792PMC
March 2014

Cooperative interaction of trp melastatin channel transient receptor potential (TRPM2) with its splice variant TRPM2 short variant is essential for endothelial cell apoptosis.

Circ Res 2014 Jan 11;114(3):469-79. Epub 2013 Dec 11.

From the Department of Pharmacology and the Center for Lung and Vascular Biology (C.M.H., M.Z., M.M., S.M.V., A.D., X.G., M.G.B., A.B.M.) and Section of Cardiology (M.G.B.), College of Medicine, University of Illinois, Chicago.

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http://dx.doi.org/10.1161/CIRCRESAHA.114.302414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978731PMC
January 2014

Bioluminescent detection of peroxynitrite with a boronic acid-caged luciferin.

Free Radic Biol Med 2013 Aug 7;61:40-50. Epub 2013 Mar 7.

Department of Pharmacology, University of Illinois at Chicago, Chicago, IL 60612, USA; Section of Cardiology, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2013.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795912PMC
August 2013

Store-operated Ca2+ entry (SOCE) induced by protease-activated receptor-1 mediates STIM1 protein phosphorylation to inhibit SOCE in endothelial cells through AMP-activated protein kinase and p38β mitogen-activated protein kinase.

J Biol Chem 2013 Jun 26;288(23):17030-41. Epub 2013 Apr 26.

Department of Pharmacology and Center for Lung and Vascular Biology, College of Medicine, University of Illinois, Chicago, Illinois 60612-7343, USA.

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http://dx.doi.org/10.1074/jbc.M112.411272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675634PMC
June 2013

Transcriptional regulation of endothelial cell and vascular development.

Circ Res 2013 May;112(10):1380-400

Department of Pharmacology, Center for Lung and Vascular Biology, The University of Illinois College of Medicine, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.113.301078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730491PMC
May 2013

PKCα activation of p120-catenin serine 879 phospho-switch disassembles VE-cadherin junctions and disrupts vascular integrity.

Circ Res 2012 Aug 12;111(6):739-49. Epub 2012 Jul 12.

Department of Pharmacology, Center for Lung and Vascular Biology, University of Illinois College of Medicine, 835 S Wolcott Ave, M/C 86, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.112.269654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518422PMC
August 2012

Sphingosine kinase 1 mediation of expression of the anaphylatoxin receptor C5L2 dampens the inflammatory response to endotoxin.

PLoS One 2012 15;7(2):e30742. Epub 2012 Feb 15.

Department of Pharmacology, College of Medicine, Center of Lung and Vascular Biology, University of Illinois, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030742PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280265PMC
June 2012

Bidirectional regulation of neutrophil migration by mitogen-activated protein kinases.

Nat Immunol 2012 Mar 25;13(5):457-64. Epub 2012 Mar 25.

Department of Dermatology, University of Illinois College of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1038/ni.2258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330201PMC
March 2012

Cytoskeletal dynamics and lung fluid balance.

Compr Physiol 2012 Jan;2(1):449-78

Department of Pharmacology, University of Illinois College of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1002/cphy.c100006DOI Listing
January 2012

Improvement of cardiac function in mouse myocardial infarction after transplantation of epigenetically-modified bone marrow progenitor cells.

PLoS One 2011 22;6(7):e22550. Epub 2011 Jul 22.

Department of Pharmacology and Center of Lung and Vascular Biology, University of Illinois College of Medicine, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022550PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142193PMC
December 2011

Permeability of endothelial barrier: cell culture and in vivo models.

Methods Mol Biol 2011 ;763:333-54

Department of Pharmacology, University of Illinois, Chicago, IL, USA.

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http://dx.doi.org/10.1007/978-1-61779-191-8_23DOI Listing
December 2011

The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation.

Nat Immunol 2011 Nov 20;13(1):29-34. Epub 2011 Nov 20.

Department of Pharmacology and Center for Lung and Vascular Biology, College of Medicine, University of Illinois, Chicago, Illinois, USA.

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http://www.nature.com/articles/ni.2171
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http://dx.doi.org/10.1038/ni.2171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242890PMC
November 2011

Delivery of nanoparticle: complexed drugs across the vascular endothelial barrier via caveolae.

IUBMB Life 2011 Aug 15;63(8):659-67. Epub 2011 Jul 15.

Department of Pharmacology and Center for Lung and Vascular Biology, College of Medicine, University of Illinois, Chicago, USA.

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http://dx.doi.org/10.1002/iub.485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142311PMC
August 2011

FoxM1 mediates the progenitor function of type II epithelial cells in repairing alveolar injury induced by Pseudomonas aeruginosa.

J Exp Med 2011 Jul 27;208(7):1473-84. Epub 2011 Jun 27.

Department of Pharmacology, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1084/jem.20102041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135362PMC
July 2011