Ashley Strougo

Ashley Strougo

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Ashley Strougo

Ashley Strougo

Publications by authors named "Ashley Strougo"

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Predicting the "First dose in children" of CYP3A-metabolized drugs: Evaluation of scaling approaches and insights into the CYP3A7-CYP3A4 switch at young ages.

J Clin Pharmacol 2014 Sep 28;54(9):1006-15. Epub 2014 Mar 28.

Division of Pharmacology, Leiden/Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands; Global Clinical Pharmacology and Exploratory Development, Astellas Pharma Europe, Leiderdorp, The Netherlands.

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http://dx.doi.org/10.1002/jcph.294DOI Listing
September 2014

First dose in children: physiological insights into pharmacokinetic scaling approaches and their implications in paediatric drug development.

J Pharmacokinet Pharmacodyn 2012 Apr 5;39(2):195-203. Epub 2012 Feb 5.

Division of Pharmacology, Leiden/Amsterdam Center for Drug Research, Leiden University, Einsteinweg, 55, P.O. Box 9502, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s10928-012-9241-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306781PMC
April 2012

A semiphysiological population model for prediction of the pharmacokinetics of drugs under liver and renal disease conditions.

Drug Metab Dispos 2011 Jul 12;39(7):1278-87. Epub 2011 Apr 12.

Global Clinical Pharmacology and Exploratory Development, Astellas Pharma Global Development Europe, Elisabethhof, 1 2353 EW Leiderdorp, The Netherlands.

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http://dx.doi.org/10.1124/dmd.110.037838DOI Listing
July 2011