Ashley M Buckle

Ashley M Buckle

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Ashley M Buckle

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Structural studies of thyroid peroxidase show the monomer interacting with autoantibodies in thyroid autoimmune disease.

Endocrinology 2020 Feb 5. Epub 2020 Feb 5.

Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1210/endocr/bqaa016DOI Listing
February 2020

Strategies for Increasing Protein Stability.

Methods Mol Biol 2020 ;2073:163-181

Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-4939-9869-2_10DOI Listing
January 2020

Thyroid Peroxidase Revisited - What's New?

Horm Metab Res 2019 Dec 11;51(12):765-769. Epub 2019 Dec 11.

King's College London (Emeritus), London, UK.

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http://dx.doi.org/10.1055/a-1057-9469DOI Listing
December 2019

Ribosome Evolution and Structural Capacitance.

Front Mol Biosci 2019 14;6:123. Epub 2019 Nov 14.

LBPA, ENS Paris-Saclay, CNRS, Université Paris-Saclay, Cachan, France.

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http://dx.doi.org/10.3389/fmolb.2019.00123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872460PMC
November 2019

Integrating Experiment and Theory to Understand TCR-pMHC Dynamics.

Front Immunol 2018 7;9:2898. Epub 2018 Dec 7.

Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia.

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http://dx.doi.org/10.3389/fimmu.2018.02898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293202PMC
October 2019

Crystal structure of the inhibitor-free form of the serine protease kallikrein-4.

Acta Crystallogr F Struct Biol Commun 2019 Aug 16;75(Pt 8):543-546. Epub 2019 Jul 16.

Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, 23 Innovation Walk, Clayton, VIC 3800, Australia.

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http://dx.doi.org/10.1107/S2053230X19009610DOI Listing
August 2019

The Role of Conformational Dynamics in Abacavir-Induced Hypersensitivity Syndrome.

Sci Rep 2019 Jul 19;9(1):10523. Epub 2019 Jul 19.

Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, 3800, Australia.

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http://dx.doi.org/10.1038/s41598-019-47001-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642150PMC
July 2019

Wavelength-Dependent Fluorescent Immunosensors via Incorporation of Polarity Indicators near the Binding Interface of Antibody Fragments.

Anal Chem 2019 Jun 5;91(12):7631-7638. Epub 2019 Jun 5.

Department of Chemical Engineering, ARC Centre of Excellence in Convergent BioNano Science and Technology , Monash University , Clayton VIC 3800 , Australia.

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http://dx.doi.org/10.1021/acs.analchem.9b00445DOI Listing
June 2019

KLK4 Inhibition by Cyclic and Acyclic Peptides: Structural and Dynamical Insights into Standard-Mechanism Protease Inhibitors.

Biochemistry 2019 May 13;58(21):2524-2533. Epub 2019 May 13.

Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute , Monash University , Clayton , Victoria 3800 , Australia.

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http://pubs.acs.org/doi/10.1021/acs.biochem.9b00191
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http://dx.doi.org/10.1021/acs.biochem.9b00191DOI Listing
May 2019

Protein engineering: the potential of remote mutations.

Biochem Soc Trans 2019 04 22;47(2):701-711. Epub 2019 Mar 22.

Research School of Chemistry, Australian National University, Canberra, Australian Capital Territory, Australia

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http://dx.doi.org/10.1042/BST20180614DOI Listing
April 2019

Reactive centre loop dynamics and serpin specificity.

Sci Rep 2019 Mar 7;9(1):3870. Epub 2019 Mar 7.

Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Victoria, 3800, Australia.

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http://dx.doi.org/10.1038/s41598-019-40432-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405850PMC
March 2019

Prostate Cancer Risk-Associated Single-Nucleotide Polymorphism Affects Prostate-Specific Antigen Glycosylation and Its Function.

Clin Chem 2019 01 11;65(1):e1-e9. Epub 2018 Dec 11.

Australian Prostate Cancer Research Centre-Queensland and Cancer Program, Institute of Health and Biomedical Innovation and School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia;

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http://dx.doi.org/10.1373/clinchem.2018.295790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643286PMC
January 2019

Catalytic diversity and cell wall binding repeats in the phage-encoded endolysins.

Mol Microbiol 2018 12 13;110(6):879-896. Epub 2018 Nov 13.

Biomedicine Discovery Institute, Department of Microbiology, Monash University, Victoria, 3800, Australia.

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http://dx.doi.org/10.1111/mmi.14134DOI Listing
December 2018

Mapping the Pathway and Dynamics of Bestatin Inhibition of the Plasmodium falciparum M1 Aminopeptidase PfA-M1.

ChemMedChem 2018 12 9;13(23):2504-2513. Epub 2018 Nov 9.

Infection and Immunity Program, Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, 3800, Australia.

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http://dx.doi.org/10.1002/cmdc.201800563DOI Listing
December 2018

Thyroid Peroxidase as an Autoantigen in Hashimoto's Disease: Structure, Function, and Antigenicity.

Horm Metab Res 2018 Dec 25;50(12):908-921. Epub 2018 Oct 25.

Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1055/a-0717-5514DOI Listing
December 2018

Structural Capacitance in Protein Evolution and Human Diseases.

J Mol Biol 2018 09 3;430(18 Pt B):3200-3217. Epub 2018 Jul 3.

Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2018.06.051DOI Listing
September 2018

Generation of AMBER force field parameters for zinc centres of M1 and M17 family aminopeptidases.

J Biomol Struct Dyn 2018 Aug 28;36(10):2595-2604. Epub 2017 Aug 28.

a Infection and Immunity Program, Department of Microbiology, Biomedicine Discovery Institute , Monash University , Clayton , Victoria 3800 , Australia.

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http://dx.doi.org/10.1080/07391102.2017.1364669DOI Listing
August 2018

Substrate Locking Promotes Dimer-Dimer Docking of an Enzyme Antibiotic Target.

Structure 2018 07 24;26(7):948-959.e5. Epub 2018 May 24.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, 30 Flemington Road, University of Melbourne, Parkville, VIC 3010, Australia; Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC 3086, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.str.2018.04.014DOI Listing
July 2018

Laboratory evolution of protein conformational dynamics.

Curr Opin Struct Biol 2018 06 8;50:49-57. Epub 2017 Nov 8.

Research School of Chemistry, Australian National University, Canberra, ACT 2601, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.sbi.2017.09.005DOI Listing
June 2018

Previously Hidden Dynamics at the TCR-Peptide-MHC Interface Revealed.

J Immunol 2018 06 4;200(12):4134-4145. Epub 2018 May 4.

Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia; and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia

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http://dx.doi.org/10.4049/jimmunol.1800315DOI Listing
June 2018

Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V.

Sci Rep 2018 01 10;8(1):358. Epub 2018 Jan 10.

Infection & Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1038/s41598-017-18742-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762688PMC
January 2018

Structural reconstruction of protein ancestry.

Proc Natl Acad Sci U S A 2017 04 29;114(15):3897-3902. Epub 2017 Mar 29.

Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia;

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http://dx.doi.org/10.1073/pnas.1613477114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393204PMC
April 2017

Circumventing the stability-function trade-off in an engineered FN3 domain.

Protein Eng Des Sel 2016 Nov;29(11):541-550

Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.

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http://dx.doi.org/10.1093/protein/gzw046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081044PMC
November 2016

PolyQ 2.0: an improved version of PolyQ, a database of human polyglutamine proteins.

Database (Oxford) 2016 15;2016. Epub 2016 Mar 15.

Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology

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http://dx.doi.org/10.1093/database/baw021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792530PMC
October 2016

KinetochoreDB: a comprehensive online resource for the kinetochore and its related proteins.

Database (Oxford) 2016 17;2016. Epub 2016 Mar 17.

Infection and Immunity Program, Biomedicine Discovery Institute and the Department of Biochemistry and Molecular Biology, Faculty of Medicine, Monash University, Melbourne, Victoria, 3800, Australia Monash Centre for Data Science, Faculty of Information Technology, Monash University, Victoria, 3800, Australia, and National Engineering Laboratory of Industrial Enzymes and Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China

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http://dx.doi.org/10.1093/database/baw019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795933PMC
October 2016

Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics.

Sci Rep 2016 10 21;6:35385. Epub 2016 Oct 21.

Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1038/srep35385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073354PMC
October 2016

Consensus protein design.

Protein Eng Des Sel 2016 07 5;29(7):245-51. Epub 2016 Jun 5.

Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Faculty of Medicine, Monash University, Clayton, Victoria 3800, Australia

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http://dx.doi.org/10.1093/protein/gzw015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917058PMC
July 2016

Dynamic Motion and Communication in the Streptococcal C1 Phage Lysin, PlyC.

PLoS One 2015 15;10(10):e0140219. Epub 2015 Oct 15.

Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia; Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140219PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607406PMC
June 2016

A colostrum trypsin inhibitor gene expressed in the Cape fur seal mammary gland during lactation.

Gene 2016 Mar 27;578(1):7-16. Epub 2015 Nov 27.

School of BioSciences, The University of Melbourne, Melbourne, VIC 3010, Australia; Cooperative Research Centre for Innovative Dairy Products, Australia; School of Life and Environmental Sciences, Deakin University, Burwood, VIC 3125, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2015.11.042DOI Listing
March 2016

Solution structure of a soluble fragment derived from a membrane protein by shotgun proteolysis.

Protein Eng Des Sel 2015 Oct 15;28(10):445-50. Epub 2015 Apr 15.

Department of Immunology, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia Faculty of Medicine, St Vincent's Clinical School, The University of New South Wales, Darlinghurst, Sydney, NSW 2010, Australia

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http://dx.doi.org/10.1093/protein/gzv021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661788PMC
October 2015

Structural and dynamic properties that govern the stability of an engineered fibronectin type III domain.

Protein Eng Des Sel 2015 Mar;28(3):67-78

Department of Biochemistry and Molecular Biology, Faculty of Medicine, School of Biomedical Sciences, Monash University, Clayton, VIC 3800, Australia

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http://dx.doi.org/10.1093/protein/gzv002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330816PMC
March 2015

Understanding the structural dynamics of TCR-pMHC complex interactions.

Trends Immunol 2014 12 11;35(12):604-612. Epub 2014 Nov 11.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia 3800. Electronic address:

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http://dx.doi.org/10.1016/j.it.2014.10.005DOI Listing
December 2014

Operation of the Australian Store.Synchrotron for macromolecular crystallography.

Acta Crystallogr D Biol Crystallogr 2014 Oct 30;70(Pt 10):2510-9. Epub 2014 Sep 30.

Monash Bioinformatics Platform, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1107/S1399004714016174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187999PMC
October 2014

PLP-dependent enzymes.

Biomed Res Int 2014 15;2014:856076. Epub 2014 Jan 15.

Section of Biological Chemistry, Department of Life Sciences and Reproduction, University of Verona, Strada Le Grazie 8, 37134 Verona, Italy.

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http://dx.doi.org/10.1155/2014/856076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914556PMC
September 2014

Oxidation of an exposed methionine instigates the aggregation of glyceraldehyde-3-phosphate dehydrogenase.

J Biol Chem 2014 Sep 1;289(39):26922-36. Epub 2014 Aug 1.

From the Australian Centre for Blood Diseases, Monash University, Melbourne 3004, Victoria, Australia and

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http://dx.doi.org/10.1074/jbc.M114.570275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175333PMC
September 2014

The α-importome of mammalian germ cell maturation provides novel insights for importin biology.

FASEB J 2014 Aug 30;28(8):3480-93. Epub 2014 Apr 30.

Department of Biochemistry and Molecular Biology and.

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http://dx.doi.org/10.1096/fj.13-244913DOI Listing
August 2014

A redundant role of human thyroid peroxidase propeptide for cellular, enzymatic, and immunological activity.

Thyroid 2014 Feb 26;24(2):371-82. Epub 2013 Sep 26.

1 Department of Biochemistry and Molecular Biology, Medical Center of Postgraduate Education , Warsaw, Poland .

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http://dx.doi.org/10.1089/thy.2013.0127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926150PMC
February 2014

Interactive visualization tools for the structural biologist.

J Appl Crystallogr 2013 Oct 3;46(Pt 5):1518-1520. Epub 2013 Aug 3.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1107/S0021889813017858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778324PMC
October 2013

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1.

Biopolymers 2013 Sep;100(5):510-8

Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, 4059, Australia.

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http://doi.wiley.com/10.1002/bip.22231
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http://dx.doi.org/10.1002/bip.22231DOI Listing
September 2013

Yersinia enterocolitica provides the link between thyroid-stimulating antibodies and their germline counterparts in Graves' disease.

J Immunol 2013 Jun 29;190(11):5373-81. Epub 2013 Apr 29.

Division of Diabetes and Nutritional Sciences, King's College London School of Medicine, London SE5 9NU, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.1203412DOI Listing
June 2013

Molecular determinants of the substrate specificity of the complement-initiating protease, C1r.

J Biol Chem 2013 May 15;288(22):15571-80. Epub 2013 Apr 15.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1074/jbc.M113.451757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668718PMC
May 2013

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1.

Biopolymers 2013 Mar 11. Epub 2013 Mar 11.

Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, 4059, Australia.

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http://dx.doi.org/10.1002/peps.22231DOI Listing
March 2013

Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates.

Biosci Rep 2013 Jan 11;33(1):137-44. Epub 2013 Jan 11.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne, VIC 3800, Australia.

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http://dx.doi.org/10.1042/BSR20120111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546353PMC
January 2013

X-ray crystal structure of the streptococcal specific phage lysin PlyC.

Proc Natl Acad Sci U S A 2012 Jul 17;109(31):12752-7. Epub 2012 Jul 17.

Department of Biochemistry and Molecular Biology, Monash University, Clayton 3800, Australia.

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http://dx.doi.org/10.1073/pnas.1208424109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412044PMC
July 2012

Epitope flexibility and dynamic footprint revealed by molecular dynamics of a pMHC-TCR complex.

PLoS Comput Biol 2012 8;8(3):e1002404. Epub 2012 Mar 8.

Department of Biochemistry and Molecular Biology, Monash University, Victoria, Australia.

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http://dx.doi.org/10.1371/journal.pcbi.1002404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297556PMC
June 2012

Hybrid approaches to molecular simulation.

Curr Opin Struct Biol 2012 Jun 25;22(3):386-93. Epub 2012 May 25.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1016/j.sbi.2012.05.005DOI Listing
June 2012

Conformational properties of the disease-causing Z variant of α1-antitrypsin revealed by theory and experiment.

Biophys J 2012 Jun 19;102(12):2856-65. Epub 2012 Jun 19.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1016/j.bpj.2012.05.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379022PMC
June 2012

Computational methods for studying serpin conformational change and structural plasticity.

Methods Enzymol 2011 ;501:295-323

Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/B978-0-12-385950-1.00014-6DOI Listing
March 2012

The rate of polyQ-mediated aggregation is dramatically affected by the number and location of surrounding domains.

J Mol Biol 2011 Nov 16;413(4):879-87. Epub 2011 Sep 16.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S002228361101020
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http://dx.doi.org/10.1016/j.jmb.2011.09.014DOI Listing
November 2011

Refolding your protein with a little help from REFOLD.

Methods Mol Biol 2011 ;752:45-57

Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-60327-223-0_4DOI Listing
October 2011

Membrane proteins of Pseudoalteromonas tunicata during the transition from planktonic to extracellular matrix-adherent state.

Environ Microbiol Rep 2011 Jun 21;3(3):405-13. Epub 2011 Mar 21.

Departments of Biochemistry and Molecular Biology Microbiology, Monash University, Clayton, Vic. 3800, Australia Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Clayton, Vic. 3800, Australia Centre for Marine Bio-Innovation and School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia.

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http://dx.doi.org/10.1111/j.1758-2229.2011.00246.xDOI Listing
June 2011

An analysis of the cross-reactivity of autoantibodies to GAD65 and GAD67 in diabetes.

PLoS One 2011 Apr 8;6(4):e18411. Epub 2011 Apr 8.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0018411PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072979PMC
April 2011

Crystallographic and molecular dynamics analysis of loop motions unmasking the peptidoglycan-binding site in stator protein MotB of flagellar motor.

PLoS One 2011 Apr 20;6(4):e18981. Epub 2011 Apr 20.

Department of Microbiology and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0018981PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080404PMC
April 2011

Mastering the canonical loop of serine protease inhibitors: enhancing potency by optimising the internal hydrogen bond network.

PLoS One 2011 Apr 27;6(4):e19302. Epub 2011 Apr 27.

Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019302PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083445PMC
April 2011

PolyQ: a database describing the sequence and domain context of polyglutamine repeats in proteins.

Nucleic Acids Res 2011 Jan 8;39(Database issue):D272-6. Epub 2010 Nov 8.

Department of Biochemistry and Molecular Biology, Faculty of Medicine, Nursing and Health Sciences, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800, Australia.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkq1100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013692PMC
January 2011

EGM: encapsulated gene-by-gene matching to identify gene orthologs and homologous segments in genomes.

Bioinformatics 2010 Sep 27;26(17):2076-84. Epub 2010 Jun 27.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.

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http://dx.doi.org/10.1093/bioinformatics/btq339DOI Listing
September 2010

Characterisation of peptide microarrays for studying antibody-antigen binding using surface plasmon resonance imagery.

PLoS One 2010 Aug 13;5(8):e12152. Epub 2010 Aug 13.

Dynamics of Macromolecular Complexes, Laboratoire de Biologie et Pharmacologie Appliquée, UMR 8113 du CNRS, Institut d'Alembert, Ecole Normale Supérieure de Cachan, Cachan, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012152PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921342PMC
August 2010

Structural biology of the GAD autoantigen.

Autoimmun Rev 2010 Jan 22;9(3):148-52. Epub 2009 May 22.

Department of Biochemistry and Molecular Biology, Monash University, Clayton Campus, Melbourne, VIC 3800, Australia.

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http://dx.doi.org/10.1016/j.autrev.2009.05.003DOI Listing
January 2010

Structural determinants of GAD antigenicity.

Mol Immunol 2009 Dec 23;47(2-3):493-505. Epub 2009 Sep 23.

The Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne, VIC 3800, Australia.

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http://dx.doi.org/10.1016/j.molimm.2009.08.022DOI Listing
December 2009

Prodepth: predict residue depth by support vector regression approach from protein sequences only.

PLoS One 2009 Sep 17;4(9):e7072. Epub 2009 Sep 17.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007072PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742725PMC
September 2009

Scabies mite inactivated serine protease paralogs inhibit the human complement system.

J Immunol 2009 Jun;182(12):7809-17

Department of Laboratory Medicine, Wallenberg Laboratory, University Hospital Malmö, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.4049/jimmunol.0804205DOI Listing
June 2009

Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase.

Proc Natl Acad Sci U S A 2009 Feb 5;106(8):2537-42. Epub 2009 Feb 5.

Department of Biochemistry and Molecular Biology and Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Clayton, Victoria, 3800, Australia.

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http://dx.doi.org/10.1073/pnas.0807398106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636733PMC
February 2009

The MACPF/CDC family of pore-forming toxins.

Cell Microbiol 2008 Sep 28;10(9):1765-74. Epub 2008 Jun 28.

Department of Biochemistry, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1111/j.1462-5822.2008.01191.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654483PMC
September 2008

Federated repositories of X-ray diffraction images.

Acta Crystallogr D Biol Crystallogr 2008 Jul 18;D64(Pt 7):810-4. Epub 2008 Jun 18.

The Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Faculty of Medicine, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1107/S0907444908015540DOI Listing
July 2008

COOH-terminal clustering of autoantibody and T-cell determinants on the structure of GAD65 provide insights into the molecular basis of autoreactivity.

Diabetes 2008 May 9;57(5):1293-301. Epub 2008 Jan 9.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.2337/db07-1461DOI Listing
May 2008

A structural basis for loop C-sheet polymerization in serpins.

J Mol Biol 2008 Mar 3;376(5):1348-59. Epub 2008 Jan 3.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne, VIC 3800, Australia.

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http://dx.doi.org/10.1016/j.jmb.2007.12.050DOI Listing
March 2008

X-ray crystal structure of the fibrinolysis inhibitor alpha2-antiplasmin.

Blood 2008 Feb 6;111(4):2049-52. Epub 2007 Dec 6.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia

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http://dx.doi.org/10.1182/blood-2007-09-114215DOI Listing
February 2008

The N terminus of the serpin, tengpin, functions to trap the metastable native state.

EMBO Rep 2007 Jul 8;8(7):658-63. Epub 2007 Jun 8.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne, Victoria 3800, Australia.

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http://dx.doi.org/10.1038/sj.embor.7400986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1905895PMC
July 2007

The 1.6 A crystal structure of the catalytic domain of PlyB, a bacteriophage lysin active against Bacillus anthracis.

J Mol Biol 2007 Feb 18;366(2):540-50. Epub 2006 Nov 18.

Protein Crystallography Unit, Department of Biochemistry and Molecular Biology and The ARC Centre of Excellence for Structural and Functional Microbial Genomics, Monash University, Clayton, Melbourne, VIC 3800, Australia.

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http://dx.doi.org/10.1016/j.jmb.2006.11.056DOI Listing
February 2007

Protein Folding Database (PFD 2.0): an online environment for the International Foldeomics Consortium.

Nucleic Acids Res 2007 Jan 14;35(Database issue):D304-7. Epub 2006 Dec 14.

The Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Faculty of Medicine, Monash University Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1093/nar/gkl1007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781104PMC
January 2007

An overview of the serpin superfamily.

Genome Biol 2006 30;7(5):216. Epub 2006 May 30.

Department of Biochemistry and Molecular Biology, Monash University, Clayton Campus, Melbourne VIC 3800, Australia.

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http://dx.doi.org/10.1186/gb-2006-7-5-216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779521PMC
August 2006

The crystal structure of the transthyretin-like protein from Salmonella dublin, a prokaryote 5-hydroxyisourate hydrolase.

J Mol Biol 2006 Jun 11;359(5):1389-99. Epub 2006 May 11.

The Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia.

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http://dx.doi.org/10.1016/j.jmb.2006.04.057DOI Listing
June 2006

REFOLD: an analytical database of protein refolding methods.

Protein Expr Purif 2006 Mar 15;46(1):166-71. Epub 2005 Aug 15.

Department of Biochemistry and Molecular Biology, P.O. Box 13D, Monash University, Vic. 3800, Australia.

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http://dx.doi.org/10.1016/j.pep.2005.07.022DOI Listing
March 2006

The REFOLD database: a tool for the optimization of protein expression and refolding.

Nucleic Acids Res 2006 Jan;34(Database issue):D207-12

Department of Biochemistry and Molecular Biology, PO Box 13D, Monash University, Victoria 3800, Australia.

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http://dx.doi.org/10.1093/nar/gkj080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1347443PMC
January 2006

T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide.

Nat Immunol 2005 Nov 25;6(11):1114-22. Epub 2005 Sep 25.

The Protein Crystallography Unit, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1038/ni1257DOI Listing
November 2005

Control of the coagulation system by serpins. Getting by with a little help from glycosaminoglycans.

FEBS J 2005 Oct;272(19):4842-51

Department of Biochemistry & Molecular Biology, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1111/j.1742-4658.2005.04880.xDOI Listing
October 2005