Ashley I Bush

Ashley I Bush

UNVERIFIED PROFILE

Are you Ashley I Bush?   Register this Author

Register author
Ashley I Bush

Ashley I Bush

Publications by authors named "Ashley I Bush"

Are you Ashley I Bush?   Register this Author

100Publications

2723Reads

49Profile Views

Regional iron distribution and soluble ferroprotein profiles in the healthy human brain.

Prog Neurobiol 2020 Mar 20;186:101744. Epub 2019 Dec 20.

The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pneurobio.2019.101744DOI Listing
March 2020

Cu (atsm) inhibits ferroptosis: Implications for treatment of neurodegenerative disease.

Br J Pharmacol 2020 Feb 14;177(3):656-667. Epub 2020 Jan 14.

Melbourne Dementia Research Centre, Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bph.14881DOI Listing
February 2020

The ubiquitin proteasome system and schizophrenia.

Lancet Psychiatry 2020 Feb 12. Epub 2020 Feb 12.

Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne & Melbourne Health, Parkville, VIC, Australia; Melbourne Dementia Research Centre, Florey Institute of Neuroscience and Mental Health, The University of Melbourne & Melbourne Health, Parkville, VIC, Australia; Centre for Neural Engineering, Department of Electrical and Electronic Engineering, The University of Melbourne & Melbourne Health, Parkville, VIC, Australia; The Cooperative Research Centre for Mental Health, Carlton South, VIC, Australia; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2215-0366(19)30520-6DOI Listing
February 2020

Cerebrospinal fluid ceruloplasmin levels predict cognitive decline and brain atrophy in people with underlying β-amyloid pathology.

Neurobiol Dis 2020 Feb 19;139:104810. Epub 2020 Feb 19.

Melbourne Dementia Research Centre, The Florey Institute for Neuroscience and Mental Health, The University of Melbourne, Victoria, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nbd.2020.104810DOI Listing
February 2020

Iron chelation by deferiprone does not rescue the Niemann-Pick Disease Type C1 mouse model.

Biometals 2020 Feb 25. Epub 2020 Feb 25.

Oxidation Biology Unit, Melbourne Dementia Research Centre, The Florey Institute of Neuroscience and Mental Health and The University of Melbourne, Melbourne, VIC, 3052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10534-020-00233-5DOI Listing
February 2020

Zinc Transporter-3 Knockout Mice Demonstrate Age-Dependent Alterations in the Metalloproteome.

Int J Mol Sci 2020 Jan 28;21(3). Epub 2020 Jan 28.

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, VIC 3010, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms21030839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037208PMC
January 2020

Redox active metals in neurodegenerative diseases.

J Biol Inorg Chem 2019 Dec 24;24(8):1141-1157. Epub 2019 Oct 24.

Melbourne Dementia Research Centre, The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, 3052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00775-019-01731-9DOI Listing
December 2019

Axonal dispatch of iron in neuronal signaling.

Nat Chem Biol 2019 12;15(12):1135-1136

Melbourne Dementia Research Centre, Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41589-019-0394-3DOI Listing
December 2019

Preferential Neurodegeneration in the Dentate Gyrus by Amyloid β-Induced Intracellular ZnDysregulation and Its Defense Strategy.

Mol Neurobiol 2019 Dec 21. Epub 2019 Dec 21.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12035-019-01853-wDOI Listing
December 2019

Treating Alzheimer's disease by targeting iron.

Br J Pharmacol 2019 Sep 11;176(18):3622-3635. Epub 2019 Feb 11.

The Melbourne Dementia Research Centre, The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bph.14567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715619PMC
September 2019

Amyloid Precursor Protein Mediates Neuronal Protection from Rotenone Toxicity.

Mol Neurobiol 2019 Aug 5;56(8):5471-5482. Epub 2019 Jan 5.

Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12035-018-1460-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614131PMC
August 2019

Amyloid β-Induced Rapid Zn Influx into Dentate Granule Cells Attenuates Maintained LTP Followed by Retrograde Amnesia.

Mol Neurobiol 2019 Jul 20;56(7):5041-5050. Epub 2018 Nov 20.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12035-018-1429-6DOI Listing
July 2019

l-3,4-dihydroxyphenylalanine (l-DOPA) modulates brain iron, dopaminergic neurodegeneration and motor dysfunction in iron overload and mutant alpha-synuclein mouse models of Parkinson's disease.

J Neurochem 2019 07 28;150(1):88-106. Epub 2019 Mar 28.

Melbourne Dementia Research Centre at The Florey Institute of Neuroscience and Mental Health and The University of Melbourne, Parkville, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jnc.14676DOI Listing
July 2019

The Effects of Clioquinol on P-glycoprotein Expression and Biometal Distribution in the Mouse Brain Microvasculature.

J Pharm Sci 2019 Jul 7;108(7):2247-2255. Epub 2019 Feb 7.

Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.xphs.2019.01.030DOI Listing
July 2019

Decreasing iron neurotoxicity in pantothenate kinase-associated neurodegeneration.

Lancet Neurol 2019 Jul;18(7):616-617

Melbourne Dementia Research Centre, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC 3052, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1474-4422(19)30193-0DOI Listing
July 2019

Iron and Alzheimer's Disease: An Update on Emerging Mechanisms.

J Alzheimers Dis 2018 ;64(s1):S379-S395

Melbourne Dementia Research Centre, The Florey Institute of Neuroscience & Mental Health, The University of Melbourne, Parkville, VIC, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-179944DOI Listing
June 2019

Blood and brain protein levels of ubiquitin-conjugating enzyme E2K (UBE2K) are elevated in individuals with schizophrenia.

J Psychiatr Res 2019 06 8;113:51-57. Epub 2019 Mar 8.

Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne & Melbourne Health, Parkville, VIC, Australia; The Cooperative Research Centre (CRC) for Mental Health, Victoria, Australia; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada; Departments of Medical Genetics, Psychiatry, and Physiology & Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpsychires.2019.03.005DOI Listing
June 2019

Extracellular Zn-independently attenuated LTP by human amyloid β and rat amyloid β.

Biochem Biophys Res Commun 2019 Jun 10;514(3):888-892. Epub 2019 May 10.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2019.05.037DOI Listing
June 2019

Cellular Senescence and Iron Dyshomeostasis in Alzheimer's Disease.

Pharmaceuticals (Basel) 2019 Jun 19;12(2). Epub 2019 Jun 19.

Melbourne Dementia Research Centre, The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC 3052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ph12020093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630536PMC
June 2019

Metals and Alzheimer's Disease: How Far Have We Come in the Clinic?

J Alzheimers Dis 2018 ;62(3):1369-1379

The Florey Institute of Neuroscience and Mental Health, Kenneth Myer Building, The University of Melbourne, Parkville, VIC, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-170662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870044PMC
May 2019

Redox Modulating Factors Affect Longevity Regulation in Rotifers.

J Gerontol A Biol Sci Med Sci 2019 05;74(6):811-814

Department of Psychiatry, Faculty of Medicine, Albert Szent-Gyorgyi Clinical Center, University of Szeged, Hungary.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/gerona/gly193DOI Listing
May 2019

Difference in ability for extracellular Zn influx between human and rat amyloid β and its significance.

Neurotoxicology 2019 05 18;72:1-5. Epub 2019 Jan 18.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuro.2019.01.005DOI Listing
May 2019

Parkinson's disease prevalence and the association with rurality and agricultural determinants.

Parkinsonism Relat Disord 2019 04 23;61:198-202. Epub 2018 Oct 23.

School of Social Sciences, Faculty of Arts, Monash University, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.parkreldis.2018.10.026DOI Listing
April 2019

Cerebrospinal fluid ferritin levels predict brain hypometabolism in people with underlying β-amyloid pathology.

Neurobiol Dis 2019 04 14;124:335-339. Epub 2018 Dec 14.

Melbourne Dementia Research Centre, The Florey Institute for Neuroscience and Mental Health, The University of Melbourne, Victoria, Australia; Cooperative Research Center for Mental Health, Victoria, Australia. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09699961183053
Publisher Site
http://dx.doi.org/10.1016/j.nbd.2018.12.010DOI Listing
April 2019

In vivo synaptic activity-independent co-uptakes of amyloid β and Zn into dentate granule cells in the normal brain.

Sci Rep 2019 Apr 24;9(1):6498. Epub 2019 Apr 24.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-019-43012-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482136PMC
April 2019

Striking while the iron is hot: Iron metabolism and ferroptosis in neurodegeneration.

Free Radic Biol Med 2019 03 25;133:221-233. Epub 2018 Sep 25.

Department of Neurology, ALS Center, Lille University, INSERM UMRS_1171, University Hospital Center, LICEND COEN Center, Lille, France; Department of Medical Pharmacology, Lille University, INSERM UMRS_1171, University Hospital Center, LICEND COEN Center, Lille, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.freeradbiomed.2018.09.033DOI Listing
March 2019

Brain iron is associated with accelerated cognitive decline in people with Alzheimer pathology.

Mol Psychiatry 2019 Feb 18. Epub 2019 Feb 18.

Melbourne Dementia Research Centre, Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Vic, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41380-019-0375-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698435PMC
February 2019

Elevated ubiquitinated proteins in brain and blood of individuals with schizophrenia.

Sci Rep 2019 02 19;9(1):2307. Epub 2019 Feb 19.

Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne & Melbourne Health, Carlton South, VIC, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-019-38490-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381171PMC
February 2019

Molecular Mechanisms of Glutaredoxin Enzymes: Versatile Hubs for Thiol-Disulfide Exchange between Protein Thiols and Glutathione.

J Mol Biol 2019 01 12;431(2):158-177. Epub 2018 Dec 12.

School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmb.2018.12.006DOI Listing
January 2019

Zn-DTSM, A Zinc Ionophore with Therapeutic Potential for Acrodermatitis Enteropathica?

Nutrients 2019 Jan 21;11(1). Epub 2019 Jan 21.

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, 30 Royal Parade, Parkville, Victoria 3052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu11010206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356714PMC
January 2019

Adrenergic β receptor activation in the basolateral amygdala, which is intracellular Zn-dependent, rescues amyloid β-induced attenuation of dentate gyrus LTP.

Neurochem Int 2018 11 17;120:43-48. Epub 2018 Jul 17.

Department of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuint.2018.07.005DOI Listing
November 2018

Overcoming the Blood-Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases.

Adv Mater 2018 Nov 31;30(46):e1801362. Epub 2018 Jul 31.

ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, and the Department of Chemical Engineering, The University of Melbourne, Parkville, Victoria, 3010, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/adma.201801362DOI Listing
November 2018

Novel Defense by Metallothionein Induction Against Cognitive Decline: From Amyloid β-Induced Excess Zn to Functional Zn Deficiency.

Mol Neurobiol 2018 Oct 19;55(10):7775-7788. Epub 2018 Feb 19.

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, 3052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12035-018-0948-5DOI Listing
October 2018

Association of metals with the risk and clinical characteristics of Parkinson's disease.

Parkinsonism Relat Disord 2018 10 28;55:117-121. Epub 2018 May 28.

Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.parkreldis.2018.05.022DOI Listing
October 2018

Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice.

Neurotherapeutics 2018 10;15(4):1055-1062

Melbourne Dementia Research Centre, The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, 30 Royal Parade, Parkville, 3052, Victoria, Australia.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s13311-018-0656-x
Publisher Site
http://dx.doi.org/10.1007/s13311-018-0656-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277293PMC
October 2018

Targeting metals rescues the phenotype in an animal model of tauopathy.

Metallomics 2018 09;10(9):1339-1347

The Florey Institute for Neuroscience and Mental Health and The University of Melbourne, Parkville, 30 Royal Parade, Victoria 3052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c8mt00153gDOI Listing
September 2018

Ablation of tau causes an olfactory deficit in a murine model of Parkinson's disease.

Acta Neuropathol Commun 2018 07 5;6(1):57. Epub 2018 Jul 5.

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, 3010, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40478-018-0560-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032546PMC
July 2018

Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis.

Redox Biol 2018 04 1;14:100-115. Epub 2017 Sep 1.

Centre for Cellular and Molecular Biology, School of Life and Environmental Sciences, Deakin University, Burwood, Victoria 3125, Australia; Department of Pathology, The University of Melbourne, Parkville, Victoria 3010, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.redox.2017.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596264PMC
April 2018

Iron as a therapeutic target for Parkinson's disease.

Mov Disord 2018 04 30;33(4):568-574. Epub 2018 Jan 30.

Université de Lille, CHU de Lille, INSERM UMRS_1171, Service de Pharmacologie Clinique et Service de Neurologie NS-Park/FCRIN Network LICEND COEN Center, Lille, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mds.27275DOI Listing
April 2018

Ionophore and Biometal Modulation of P-glycoprotein Expression and Function in Human Brain Microvascular Endothelial Cells.

Pharm Res 2018 Mar 5;35(4):83. Epub 2018 Mar 5.

Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences,, Monash University,, 381 Royal Parade, Parkville, VIC,, 3052, Australia.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11095-018-2377-6
Publisher Site
http://dx.doi.org/10.1007/s11095-018-2377-6DOI Listing
March 2018

Evidence of a Cardiovascular Function for Microtubule-Associated Protein Tau.

J Alzheimers Dis 2017 ;56(2):849-860

Department of Pharmacology and Therapeutics, Cardiovascular Therapeutics Unit, The University of Melbourne, VIC, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-161093DOI Listing
February 2018

Glutaredoxins employ parallel monothiol-dithiol mechanisms to catalyze thiol-disulfide exchanges with protein disulfides.

Chem Sci 2018 Feb 6;9(5):1173-1183. Epub 2017 Dec 6.

School of Chemistry , Bio21 Molecular Science and Biotechnology Institute , The University of Melbourne , Parkville , Victoria 3010 , Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c7sc04416jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885593PMC
February 2018

S-sulfocysteine/NMDA receptor-dependent signaling underlies neurodegeneration in molybdenum cofactor deficiency.

J Clin Invest 2017 12 6;127(12):4365-4378. Epub 2017 Nov 6.

Institute of Biochemistry, Department of Chemistry, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI89885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707142PMC
December 2017

Reduction potentials of protein disulfides and catalysis of glutathionylation and deglutathionylation by glutaredoxin enzymes.

Biochem J 2017 11 9;474(22):3799-3815. Epub 2017 Nov 9.

School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BCJ20170589DOI Listing
November 2017

Novel in vivo experimental viability assays with high sensitivity and throughput capacity using a bdelloid rotifer.

Ecotoxicol Environ Saf 2017 Oct 9;144:115-122. Epub 2017 Jun 9.

Department of Psychiatry, University of Szeged, Szeged, Hungary. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ecoenv.2017.06.005DOI Listing
October 2017

Nanoscale Imaging Reveals Big Role for Iron in Alzheimer's Disease.

Cell Chem Biol 2017 Oct;24(10):1192-1194

Melbourne Dementia Research Centre, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chembiol.2017.10.002DOI Listing
October 2017

Human Basic Fibroblast Growth Factor Inhibits Tau Phosphorylation via the PI3K/Akt-GSK3β Signaling Pathway in a 6-Hydroxydopamine-Induced Model of Parkinson's Disease.

Neurodegener Dis 2016 27;16(5-6):357-69. Epub 2016 May 27.

Institute of Biomedicine and National Engineering Research Center of Genetic Medicine, Jinan University, Guangzhou, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000445871DOI Listing
September 2017

Accelerated kindling epileptogenesis in Tg4510 tau transgenic mice, but not in tau knockout mice.

Epilepsia 2017 09 15;58(9):e136-e141. Epub 2017 Jul 15.

Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/epi.13847DOI Listing
September 2017

The APOE ε4 Allele Is Associated with Lower Selenium Levels in the Brain: Implications for Alzheimer's Disease.

ACS Chem Neurosci 2017 07 3;8(7):1459-1464. Epub 2017 May 3.

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne , Parkville, Victoria 3052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acschemneuro.7b00014DOI Listing
July 2017

Extracellular Zn Is Essential for Amyloid β-Induced Cognitive Decline in the Normal Brain and Its Rescue.

J Neurosci 2017 07 26;37(30):7253-7262. Epub 2017 Jun 26.

Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, 3052 Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1523/JNEUROSCI.0954-17.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705735PMC
July 2017

Characterization and Identification of Dityrosine Cross-Linked Peptides Using Tandem Mass Spectrometry.

Anal Chem 2017 06 18;89(11):6136-6145. Epub 2017 May 18.

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne , 30 Royal Parade, Parkville, Victoria 3052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.analchem.7b00941DOI Listing
June 2017

Tat-haFGF Upregulates ADAM10 to Attenuate the Alzheimer Phenotype of APP/PS1 Mice through the PI3K-CREB-IRE1α/XBP1 Pathway.

Mol Ther Nucleic Acids 2017 Jun 10;7:439-452. Epub 2017 May 10.

Guangdong Provincial Key Laboratory of Bioengineering Medicine, Jinan University, Guangzhou 510632, China; Cell Biology Department and National Engineering Research Center of Genetic Medicine, Jinan University, Guangzhou 510632, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.omtn.2017.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443968PMC
June 2017

Oxidation of Iron under Physiologically Relevant Conditions in Biological Fluids from Healthy and Alzheimer's Disease Subjects.

ACS Chem Neurosci 2017 04 3;8(4):731-736. Epub 2017 Jan 3.

Oxidation Biology Unit, The Florey Institute of Neuroscience and Mental Health, The University of Melbourne , Parkville, Victoria 3010, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acschemneuro.6b00411DOI Listing
April 2017

Editorial: The CB2 Cannabinoid System: A New Strategy in Neurodegenerative Disorder and Neuroinflammation.

Front Neurosci 2017 6;11:196. Epub 2017 Apr 6.

Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari Aldo MoroBari, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnins.2017.00196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382166PMC
April 2017

Ferroptosis and cell death mechanisms in Parkinson's disease.

Neurochem Int 2017 Mar 9;104:34-48. Epub 2017 Jan 9.

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, 30 Royal Parade, Parkville, Victoria 3052, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuint.2017.01.004DOI Listing
March 2017

Association of Cerebrospinal Fluid Ferritin Level With Preclinical Cognitive Decline in APOE-ε4 Carriers.

JAMA Neurol 2017 01;74(1):122-125

The Florey Institute for Neuroscience and Mental Health, The University of Melbourne, Melbourne, Australia3Cooperative Research Center for Mental Health, Melbourne, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaneurol.2016.4406DOI Listing
January 2017

Overexpression of Metallothionein-1 Modulates the Phenotype of the Tg2576 Mouse Model of Alzheimer's Disease.

J Alzheimers Dis 2016 ;51(1):81-95

Animal Physiology Unit, Department of Cellular Biology, Physiology and Immunology, Faculty of Biosciences Bellaterra, Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-151025DOI Listing
December 2016

Iron Regulates Apolipoprotein E Expression and Secretion in Neurons and Astrocytes.

J Alzheimers Dis 2016 ;51(2):471-87

The Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-150797DOI Listing
December 2016

The Complex Role of Apolipoprotein E in Alzheimer's Disease: an Overview and Update.

J Mol Neurosci 2016 Nov 19;60(3):325-335. Epub 2016 Sep 19.

The Florey Institute for Neuroscience and Mental Health, The University of Melbourne, 30 Royal Parade, Parkville, VIC, 3052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12031-016-0839-zDOI Listing
November 2016

Delivery of Fluorescent Nanoparticles to the Brain.

J Mol Neurosci 2016 Nov 22;60(3):405-409. Epub 2016 Sep 22.

The Florey Institute for Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, 3052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12031-016-0833-5DOI Listing
November 2016

Dementia Research Australia: the Australian Dementia Research Development Fellowship Program.

J Mol Neurosci 2016 Nov;60(3):277-278

Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, 3010, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12031-016-0842-4DOI Listing
November 2016

Iron neurochemistry in Alzheimer's disease and Parkinson's disease: targets for therapeutics.

J Neurochem 2016 10 10;139 Suppl 1:179-197. Epub 2016 Feb 10.

The Florey Institute for Neuroscience and Mental Health, The University of Melbourne, Parkville, Vic., Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jnc.13425DOI Listing
October 2016

Amyloid β attenuates metabotropic zinc sensing receptor, mZnR/GPR39, dependent Ca , ERK1/2 and Clusterin signaling in neurons.

J Neurochem 2016 10 15;139(2):221-233. Epub 2016 Sep 15.

Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jnc.13760DOI Listing
October 2016

Predicting Alzheimer disease from a blood-based biomarker profile: A 54-month follow-up.

Neurology 2016 Sep 17;87(11):1093-101. Epub 2016 Aug 17.

From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne, Parkville; eHealth (J.D.D.), CSIRO Health and Biosecurity, Herston; Centre of Excellence for Alzheimer's Disease Research & Care (S.M.L., R.N.M., S.R.-S.), School of Medical Sciences, Edith Cowan University, Joondalup; School of Biomedical Sciences (S.M.L.), Faculty of Health Sciences, Curtin University, Bentley; Sir James McCusker Alzheimer's Disease Research Unit (Hollywood Private Hospital) (R.N.M., S.R.-S.), Perth; Cogstate (P.M.), Melbourne; CSIRO Food and Nutrition Flagship (S.L.M.), Melbourne; Department of Psychology (G.S.), Macquarie University, Sydney; and eHealth (W.W.), CSIRO Health and Biosecurity, North Ryde, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000003094DOI Listing
September 2016

Transferrin protects against Parkinsonian neurotoxicity and is deficient in Parkinson's substantia nigra.

Signal Transduct Target Ther 2016 2;1:16015. Epub 2016 Sep 2.

The Florey Institute for Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sigtrans.2016.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661661PMC
September 2016

Lead and manganese levels in serum and erythrocytes in Alzheimer's disease and mild cognitive impairment: results from the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing.

Metallomics 2016 06;8(6):628-32

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia. and Cooperative Research Centre for Mental Health, Carlton South, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c6mt00019cDOI Listing
June 2016

Increased cortical expression of the zinc transporter SLC39A12 suggests a breakdown in zinc cellular homeostasis as part of the pathophysiology of schizophrenia.

NPJ Schizophr 2016 9;2:16002. Epub 2016 Mar 9.

The Molecular Psychiatry Laboratory, The Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia; Department of Psychaitry, University of Melbourne, Melbourne, VIC, Australia; CRC for Mental Health, Carlton South, VIC, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/npjschz.2016.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898896PMC
June 2016

Plasma apolipoprotein J as a potential biomarker for Alzheimer's disease: Australian Imaging, Biomarkers and Lifestyle study of aging.

Alzheimers Dement (Amst) 2016 22;3:18-26. Epub 2015 Dec 22.

School of Medical Sciences, Edith Cowan University, Joondalup, WA, Australia; Cooperative Research Centre for Mental Health, Melbourne, Australia; School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dadm.2015.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879652PMC
May 2016

Effects of Neonatal Iron Feeding and Chronic Clioquinol Administration on the Parkinsonian Human A53T Transgenic Mouse.

ACS Chem Neurosci 2016 Mar 7;7(3):360-6. Epub 2016 Jan 7.

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne , Parkville, Victoria 3052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acschemneuro.5b00305DOI Listing
March 2016

High-resolution complementary chemical imaging of bio-elements in Caenorhabditis elegans.

Metallomics 2016 Feb;8(2):156-60

The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria 3010, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c5mt00288eDOI Listing
February 2016

φXANES: In vivo imaging of metal-protein coordination environments.

Sci Rep 2016 Feb 10;6:20350. Epub 2016 Feb 10.

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, 3052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep20350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748213PMC
February 2016

Benefits of adjunctive N-acetylcysteine in a sub-group of clozapine-treated individuals diagnosed with schizophrenia.

Psychiatry Res 2015 Dec 2;230(3):982-3. Epub 2015 Nov 2.

IMPACT Strategic Research Centre, Deakin University, Geelong, Australia; Florey Institute for Neuroscience and Mental Health, Parkville, Australia; Department of Psychiatry, University of Melbourne, Parkville, Australia; Barwon Health, Geelong, Australia; Orygen Research Centre, Parkville, Australia.

View Article

Download full-text PDF

Source
https://www.alamaya.net/wp-content/uploads/2015/04/Dean_Psyc
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S016517811530605
Publisher Site
http://dx.doi.org/10.1016/j.psychres.2015.10.037DOI Listing
December 2015