Ashley Cast

Ashley Cast

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Ashley Cast

Ashley Cast

Publications by authors named "Ashley Cast"

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14Publications

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Liver Proliferation Is an Essential Driver of Fibrosis in Mouse Models of Nonalcoholic Fatty Liver Disease.

Hepatol Commun 2019 Aug 17;3(8):1036-1049. Epub 2019 Jul 17.

Department of Surgery Cincinnati Children's Hospital Medical Center Cincinnati OH.

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http://dx.doi.org/10.1002/hep4.1381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671863PMC
August 2019

Gankyrin Promotes Tumor-Suppressor Protein Degradation to Drive Hepatocyte Proliferation.

Cell Mol Gastroenterol Hepatol 2018 24;6(3):239-255. Epub 2018 May 24.

Department of Surgery, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

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http://dx.doi.org/10.1016/j.jcmgh.2018.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083020PMC
July 2019

Elimination of Age-Associated Hepatic Steatosis and Correction of Aging Phenotype by Inhibition of cdk4-C/EBPα-p300 Axis.

Cell Rep 2018 08;24(6):1597-1609

Department of Surgery, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183109
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http://dx.doi.org/10.1016/j.celrep.2018.07.014DOI Listing
August 2018

Correction of aging phenotype in the liver.

Aging (Albany NY) 2018 Aug;10(8):1795-1796

Department of Surgery Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.18632/aging.101523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128412PMC
August 2018

C/EBPα-dependent preneoplastic tumor foci are the origin of hepatocellular carcinoma and aggressive pediatric liver cancer.

Hepatology 2018 05 25;67(5):1857-1871. Epub 2018 Mar 25.

Department of Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

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http://dx.doi.org/10.1002/hep.29677DOI Listing
May 2018

RNA Binding Protein CUGBP1 Inhibits Liver Cancer in a Phosphorylation-Dependent Manner.

Mol Cell Biol 2017 Aug 28;37(16). Epub 2017 Jul 28.

Department of Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA

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http://dx.doi.org/10.1128/MCB.00128-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533886PMC
August 2017

Activation of CDK4 Triggers Development of Non-alcoholic Fatty Liver Disease.

Cell Rep 2016 07 30;16(3):744-56. Epub 2016 Jun 30.

Division of Pediatric General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center (CCHMC), 3333 Burnet Avenue ML 7015, Cincinnati, OH 45229, USA; Huffington Center on Aging, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.06.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072278PMC
July 2016

Vascular patterning sets the stage for macro and micro hepatic architecture.

Dev Dyn 2015 Mar 18;244(3):497-506. Epub 2014 Nov 18.

Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

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http://dx.doi.org/10.1002/dvdy.24222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858172PMC
March 2015

Intrahepatic bile duct regeneration in mice does not require Hnf6 or Notch signaling through Rbpj.

Am J Pathol 2014 May 13;184(5):1479-88. Epub 2014 Mar 13.

Divisions of Gastroenterology, Hepatology, and Nutrition and Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2014.01.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005980PMC
May 2014

Epithelial VEGF signaling is required in the mouse liver for proper sinusoid endothelial cell identity and hepatocyte zonation in vivo.

Am J Physiol Gastrointest Liver Physiol 2014 May 20;306(10):G849-62. Epub 2014 Mar 20.

Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

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http://ajpgi.physiology.org/content/ajpgi/306/10/G849.full.p
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http://ajpgi.physiology.org/cgi/doi/10.1152/ajpgi.00426.2013
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http://dx.doi.org/10.1152/ajpgi.00426.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024728PMC
May 2014

An essential and highly conserved role for Zic3 in left-right patterning, gastrulation and convergent extension morphogenesis.

Dev Biol 2012 Apr 21;364(1):22-31. Epub 2012 Jan 21.

Division of Molecular Cardiovascular Biology, the Heart Institute, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, 240 Albert Sabin Way, MLC 7020, Cincinnati, OH 45229-3039, USA.

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http://dx.doi.org/10.1016/j.ydbio.2012.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294024PMC
April 2012