Publications by authors named "Asha Multani"

77Publications

Establishment and characterization of a prostate cancer cell line from a prostatectomy specimen for the study of cellular interaction.

Int J Cancer 2019 10 10;145(8):2249-2259. Epub 2019 May 10.

Uro-Oncology Research, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA.

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http://dx.doi.org/10.1002/ijc.32370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703920PMC
October 2019

Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration.

Cell Host Microbe 2018 09 30;24(3):392-404.e8. Epub 2018 Aug 30.

Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368089PMC
September 2018

Evaluation of cMET aberration by immunohistochemistry and fluorescence in situ hybridization (FISH) in triple negative breast cancers.

Ann Diagn Pathol 2018 Aug 3;35:69-76. Epub 2018 May 3.

Department of Pathology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Houston, TX 77030, USA; Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA. Electronic address:

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http://dx.doi.org/10.1016/j.anndiagpath.2018.04.004DOI Listing
August 2018

Cytogenetic Analysis of Telomere Dysfunction.

Methods Mol Biol 2017 ;1587:127-131

Department of Laboratory Medicine, Yale University School of Medicine, 330 Cedar St., New Haven, CT, 06520, USA.

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http://dx.doi.org/10.1007/978-1-4939-6892-3_12DOI Listing
February 2018

Clonal evolution in breast cancer revealed by single nucleus genome sequencing.

Nature 2014 Aug 30;512(7513):155-60. Epub 2014 Jul 30.

1] The University of Texas MD Anderson Cancer Center, Department of Genetics, Houston, Texas 77030, USA [2] The University of Texas Graduate School of Biomedical Sciences, Houston, Texas 77030, USA [3] The University of Texas MD Anderson Cancer Center, Department of Bioinformatics and Computational Biology, Houston, Texas 77030, USA.

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https://dash.harvard.edu/bitstream/handle/1/14065379/4158312
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http://michorlab.dfci.harvard.edu/publications/Nature2014a.p
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http://www.nature.com/doifinder/10.1038/nature13600
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http://dx.doi.org/10.1038/nature13600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158312PMC
August 2014

Dissociated primary human prostate cancer cells coinjected with the immortalized Hs5 bone marrow stromal cells generate undifferentiated tumors in NOD/SCID-γ mice.

PLoS One 2013 22;8(2):e56903. Epub 2013 Feb 22.

Department of Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Science Park, Smithville, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0056903PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579939PMC
September 2013

Expression and activity of Fyn mediate proliferation and blastic features of chronic myelogenous leukemia.

PLoS One 2012 17;7(12):e51611. Epub 2012 Dec 17.

Department of Pediatrics Research, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0051611PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524192PMC
June 2013

Defining causative factors contributing in the activation of hedgehog signaling in diffuse large B-cell lymphoma.

Leuk Res 2012 Oct 17;36(10):1267-73. Epub 2012 Jul 17.

Molecular Genetic Technology Program, School of Health Sciences, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.leukres.2012.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422406PMC
October 2012

Targeting low molecular weight cyclin E (LMW-E) in breast cancer.

Breast Cancer Res Treat 2012 Apr 22;132(2):575-88. Epub 2011 Jun 22.

Department of Experimental Radiation Oncology, M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s10549-011-1638-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855283PMC
April 2012

Cytogenetic analysis of telomere dysfunction.

Methods Mol Biol 2011 ;735:139-43

Department of Genetics, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1007/978-1-61779-092-8_13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725757PMC
August 2011

The RAG2 C terminus suppresses genomic instability and lymphomagenesis.

Nature 2011 Mar;471(7336):119-23

Department of Pathology, New York University School of Medicine, New York, NY 10016, USA.

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http://dx.doi.org/10.1038/nature09755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174233PMC
March 2011

Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance.

Mol Cell 2009 Aug;35(3):352-64

Department of Biochemistry and Molecular Biology, University of Texas M.D. Anderson Cancer Center, Houston, 77030, USA.

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http://dx.doi.org/10.1016/j.molcel.2009.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749492PMC
August 2009

9-bromonoscapine-induced mitotic arrest of cigarette smoke condensate-transformed breast epithelial cells.

J Cell Biochem 2009 Apr;106(6):1146-56

Department of Anatomy and Cell Biology and UF Shands Cancer Center, University of Florida, Gainesville, Florida 32610, USA.

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http://dx.doi.org/10.1002/jcb.22099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728348PMC
April 2009

Cyclooxygenase-2 induces genomic instability, BCL2 expression, doxorubicin resistance, and altered cancer-initiating cell phenotype in MCF7 breast cancer cells.

J Surg Res 2008 Jun 18;147(2):240-6. Epub 2008 Mar 18.

Department of Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1016/j.jss.2008.02.026DOI Listing
June 2008

Control of chromosome stability by the beta-TrCP-REST-Mad2 axis.

Nature 2008 Mar;452(7185):365-9

Department of Pathology, NYU Cancer Institute, New York University School of Medicine, 550 First Avenue, MSB 599, New York, New York 10016, USA.

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http://www.nature.com/articles/nature06641
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http://dx.doi.org/10.1038/nature06641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707768PMC
March 2008

Evidence that senescent human prostate epithelial cells enhance tumorigenicity: cell fusion as a potential mechanism and inhibition by p16INK4a and hTERT.

Int J Cancer 2008 Apr;122(7):1483-95

Department of Carcinogenesis, University of Texas MD Anderson Cancer Center, Science Park-Research Division, Smithville, TX 78957, USA.

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http://dx.doi.org/10.1002/ijc.23222DOI Listing
April 2008

Overexpression of the low molecular weight cyclin E in transgenic mice induces metastatic mammary carcinomas through the disruption of the ARF-p53 pathway.

Cancer Res 2007 Aug;67(15):7212-22

Department of Experimental Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-0599DOI Listing
August 2007

Cyclooxygenase-2 expression induces genomic instability in MCF10A breast epithelial cells.

J Surg Res 2007 Jun 9;140(2):220-6. Epub 2007 Apr 9.

Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1016/j.jss.2007.01.039DOI Listing
June 2007

WRN at telomeres: implications for aging and cancer.

J Cell Sci 2007 Mar;120(Pt 5):713-21

Department of Molecular Genetics, U.T. M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1242/jcs.03397DOI Listing
March 2007

POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination.

EMBO J 2006 Nov 19;25(21):5180-90. Epub 2006 Oct 19.

Department of Molecular Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/sj.emboj.7601294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1630418PMC
November 2006

Fractionated X-radiation treatment can elicit an inducible-like radioprotective response that is not dependent on the intrinsic cellular X-radiation resistance/sensitivity.

Radiat Res 2006 Oct;166(4):590-9

Centre for Cancer Therapeutics, Ottawa Health Research Institute, Ottawa, Ontario, K1H 8L6, Canada.

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http://dx.doi.org/10.1667/RR0514.1DOI Listing
October 2006

Molecular analysis of anoikis resistance in oral cavity squamous cell carcinoma.

Oral Oncol 2007 May 15;43(5):440-54. Epub 2006 Sep 15.

Department of Head and Neck Surgery, MD Anderson Cancer Center, University of Texas, 1515 Holcombe Blvd, Unit 441, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.oraloncology.2006.04.016DOI Listing
May 2007

Prostate cancer metastasis: role of the host microenvironment in promoting epithelial to mesenchymal transition and increased bone and adrenal gland metastasis.

Prostate 2006 Nov;66(15):1664-73

Department of Urology, Molecular Urology and Therapeutics Program, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1002/pros.20488DOI Listing
November 2006

BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer.

Cancer Cell 2006 Aug 27;10(2):145-57. Epub 2006 Jul 27.

Department of Molecular Therapeutics, The University of Texas M D Anderson Cancer Center, Houston, Texas 77054, USA.

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http://dx.doi.org/10.1016/j.ccr.2006.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557410PMC
August 2006

Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres.

Cell 2006 Jul;126(1):49-62

Department of Molecular Genetics, Box 1006, M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.cell.2006.05.037DOI Listing
July 2006

Aneuploidy, stem cells and cancer.

EXS 2006 (96):49-64

Department of Molecular Genetics, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1007/3-7643-7378-4_3DOI Listing
February 2006

Essential role of limiting telomeres in the pathogenesis of Werner syndrome.

Nat Genet 2004 Aug 4;36(8):877-82. Epub 2004 Jul 4.

Department of Molecular Genetics, M.D. Anderson Cancer Center, Box 11, 1515 Holcombe Blvd., Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/ng1389DOI Listing
August 2004

Drug-resistant breast carcinoma (MCF-7) cells are paradoxically sensitive to apoptosis.

J Cell Physiol 2004 Aug;200(2):223-34

Department of Bioimmunotherapy, The University of Texas, M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://doi.wiley.com/10.1002/jcp.20014
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http://dx.doi.org/10.1002/jcp.20014DOI Listing
August 2004

Tumor-specific low molecular weight forms of cyclin E induce genomic instability and resistance to p21, p27, and antiestrogens in breast cancer.

Cancer Res 2004 May;64(9):3198-208

Department of Experimental Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/0008-5472.can-03-3672DOI Listing
May 2004

Germline Telomere Length Dynamics and Mutagen Sensitivity Studies in a Family with Acute Reactions to Sun Exposure: Involvement of Three Generations.

Cancer Genomics Proteomics 2004 May-Jun;1(3):199-208. Epub 2004 May 1.

Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030.

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May 2004

Comparison of the X-radiation, drug and ultraviolet-radiation responses of clones isolated from a human colorectal tumor cell line.

Radiat Res 2004 Mar;161(3):326-34

Centre for Cancer Therapeutics, Ottawa Regional Cancer Centre, Ottawa, Ontario, K1H 1C4, Canada.

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http://dx.doi.org/10.1667/rr3144DOI Listing
March 2004

N-methyl-N'-nitro-N-nitrosoguanidine-induced senescence-like growth arrest in colon cancer cells is associated with loss of adenomatous polyposis coli protein, microtubule organization, and telomeric DNA.

Mol Cancer 2004 Jan 16;3. Epub 2004 Jan 16.

UF Shands Cancer Center and Anatomy and Cell Biology, College of Medicine, Academic Research Building, Room R4-216, PO Box 100232, University of Florida, Gainesville, FL 32610, USA.

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http://dx.doi.org/10.1186/1476-4598-3-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC320492PMC
January 2004

Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice.

Nat Genet 2004 Jan 21;36(1):63-8. Epub 2003 Dec 21.

Department of Molecular Genetics, Section of Cancer Genetics, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, Texas 77030, USA.

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http://www.nature.com/articles/ng1282
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http://dx.doi.org/10.1038/ng1282DOI Listing
January 2004

Ruta 6 selectively induces cell death in brain cancer cells but proliferation in normal peripheral blood lymphocytes: A novel treatment for human brain cancer.

Int J Oncol 2003 Oct;23(4):975-82

Department of Molecular Genetics, M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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October 2003

Molecular characterization of new melanoma cell lines from C3H mice induced by ethanol plus ultraviolet radiation.

Cancer Res 2003 Jul;63(13):3503-10

Department of Immunology-178, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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July 2003

Pleotropic effects of genistein on MCF-7 breast cancer cells.

Int J Mol Med 2003 Jul;12(1):29-34

Department of Urology and Pathology, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA.

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July 2003

Multidrug-resistant MCF-7 cells: an identity crisis?

J Natl Cancer Inst 2002 Nov;94(21):1652-4; author reply 1654

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http://dx.doi.org/10.1093/jnci/94.21.1652-bDOI Listing
November 2002

Telomere erosion-induced mitotic catastrophe in continuously grown chinese hamster don cells.

Exp Cell Res 2002 Oct;279(2):271-6

Department of Animal Science and Biotechnology, Chinju National University, Chinju, 660-758, Republic of Korea.

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http://dx.doi.org/10.1006/excr.2002.5614DOI Listing
October 2002

Characterization of a renal cell carcinoma cell line derived from a human bone metastasis and establishment of an experimental nude mouse model.

J Urol 2002 Aug;168(2):774-9

Department of Cancer Biology, University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.

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August 2002

Disruption of the NAD(P)H:quinone oxidoreductase 1 (NQO1) gene in mice causes myelogenous hyperplasia.

Cancer Res 2002 Jun;62(11):3030-6

Department of Pharmacology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

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June 2002

Human breast cancer MCF-7 cell line contains inherently drug-resistant subclones with distinct genotypic and phenotypic features.

Int J Oncol 2002 May;20(5):913-20

Department of Bioimmunotherapy, The University of Texas, M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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May 2002

Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA.

Oncogene 2002 Jan;21(6):878-89

Department of Neurosurgery, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Road, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/sj.onc.1205138DOI Listing
January 2002

Telomere dynamics, aneuploidy, stem cells, and cancer (review).

Int J Oncol 2002 Mar;20(3):637-41

Department of Cancer Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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March 2002