Arun Sreekumar

Arun Sreekumar

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Arun Sreekumar

Publications by authors named "Arun Sreekumar"

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Erratum to "Distinct Lipidomic Landscapes Associated with Clinical Stages of Urothelial Cancer of the Bladder" [Eur Urol Focus 2018;4:907-915].

Eur Urol Focus 2019 Aug 29. Epub 2019 Aug 29.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA; Dan L. Duncan Cancer Center, Advanced Technology Core, Alkek Center for Molecular Discovery, Baylor College of Medicine, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.euf.2019.08.010DOI Listing
August 2019

Distinct Lipidomic Landscapes Associated with Clinical Stages of Urothelial Cancer of the Bladder.

Eur Urol Focus 2018 12 20;4(6):907-915. Epub 2017 Apr 20.

Department of Molecular and Cell Biology, Baylor College of Medicine, Houston, TX, USA; Dan L. Duncan Cancer Center, Advanced Technology Core, Alkek Center for Molecular Discovery, Baylor College of Medicine, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.euf.2017.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650548PMC
December 2018

Current Applications of Metabolomics in Cirrhosis.

Metabolites 2018 Oct 22;8(4). Epub 2018 Oct 22.

Margaret M. and Albert B. Alkek Department of Medicine, Section of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, TX 77030, USA.

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http://www.mdpi.com/2218-1989/8/4/67
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http://dx.doi.org/10.3390/metabo8040067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316274PMC
October 2018

A Bottom-Up Approach to Understanding Low-Income Patients: Implications for Health-Related Policy.

J Law Med Ethics 2018 Sep;46(3):658-664

Madhu Viswanathan, Ph.D., is the Dianne and Steven N. Miller Centennial Chair in Business, and Founder and Director of the Subsistence Marketplaces Initiative at the Gies College of Business, University of Illinois, Urbana-Champaign, and the Marketplace Literacy Project, Illinois. Ronald Duncan, M.S., is the Associate Director of the Subsistence Marketplaces Initiative at the Gies College of Business, University of Illinois, Urbana-Champaign. Maria Grigortsuk is an undergraduate student at the Gies College of Business, University of Illinois, Urbana-Champaign. Arun Sreekumar is a doctoral candidate at the Gies College of Business, University of Illinois, Urbana-Champaign.

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http://dx.doi.org/10.1177/1073110518804220DOI Listing
September 2018

Analysis of cerebrospinal fluid metabolites in patients with primary or metastatic central nervous system tumors.

Acta Neuropathol Commun 2018 08 31;6(1):85. Epub 2018 Aug 31.

Department of Neurosurgery, University of Texas Health Science Center at Houston, 6431 Fannin St., MSB 2.136, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1186/s40478-018-0588-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117959PMC
August 2018

Potential role of Plasmodium falciparum exported protein 1 in the chloroquine mode of action.

Int J Parasitol Drugs Drug Resist 2018 04 27;8(1):31-35. Epub 2017 Dec 27.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA; Computational and Integrative Biomedical Research Center, Baylor College of Medicine, Houston, TX, 77030, USA; Department of Pharmacology, Baylor College of Medicine, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1016/j.ijpddr.2017.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963095PMC
April 2018

Metabolomics of oncogene-specific metabolic reprogramming during breast cancer.

Cancer Metab 2018 3;6. Epub 2018 Apr 3.

1Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556 USA.

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http://dx.doi.org/10.1186/s40170-018-0175-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881178PMC
April 2018

Influence of the neural microenvironment on prostate cancer.

Prostate 2018 Feb 13;78(2):128-139. Epub 2017 Nov 13.

Department of Pathology and Laboratory Medicine, University of Texas Health Sciences Center Medical School, Houston, Texas.

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http://dx.doi.org/10.1002/pros.23454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836952PMC
February 2018

ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming.

J Clin Invest 2018 01 27;128(1):323-340. Epub 2017 Nov 27.

Laboratory of Human Carcinogenesis, Center for Cancer Research (CCR), National Cancer Institute (NCI), NIH, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1172/JCI93815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749504PMC
January 2018

Loss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration.

Neuron 2017 Jan 22;93(1):115-131. Epub 2016 Dec 22.

Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA; Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2016.11.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242142PMC
January 2017

Circadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis.

Cancer Cell 2016 Dec 23;30(6):909-924. Epub 2016 Nov 23.

Department of Pediatrics/U.S. Department of Agriculture/Agricultural Research Service/Children's Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695235PMC
December 2016

MNX1 Is Oncogenically Upregulated in African-American Prostate Cancer.

Cancer Res 2016 11 30;76(21):6290-6298. Epub 2016 Aug 30.

Department of Pathology and Immunology and Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-0087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093064PMC
November 2016

Genomic Aberrations Drive Clonal Evolution of Neuroendocrine Tumors.

Trends Endocrinol Metab 2016 05 29;27(5):242-244. Epub 2016 Mar 29.

Verna and Marrs McLean Department of Biochemistry and Molecular Biology and Alkek Center for Molecular Discovery, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Cellular Biology and Alkek Center for Molecular Discovery, Baylor College of Medicine, Houston, TX 77030, USA; Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tem.2016.03.009DOI Listing
May 2016

EMT-induced metabolite signature identifies poor clinical outcome.

Oncotarget 2015 Dec;6(40):42651-60

Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.18632/oncotarget.4765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767460PMC
December 2015

A Novel [N] Glutamine Flux using LC-MS/MS-SRM for Determination of Nucleosides and Nucleobases.

J Anal Bioanal Tech 2015 Oct 30;6(5). Epub 2015 Aug 30.

Advanced Technology Core, Baylor College of Medicine, One Baylor Plaza Houston, TX, USA; Department of Molecular and Cell Biology, Baylor College of Medicine, One Baylor Plaza Houston, TX, USA; Alkek Center for Molecular Discovery, Baylor College of Medicine, One Baylor Plaza Houston, TX, USA.

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https://www.omicsonline.org/open-access/a-novel-15n-glutamin
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http://dx.doi.org/10.4172/2155-9872.1000267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857768PMC
October 2015

Metabolomic profiling of hormone-dependent cancers: a bird's eye view.

Trends Endocrinol Metab 2015 Sep 1;26(9):477-85. Epub 2015 Aug 1.

Alkek Center for Molecular Discovery, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tem.2015.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560106PMC
September 2015

Structural insights into the interaction between molluscan hemocyanins and phenolic substrates: An in silico study using docking and molecular dynamics.

J Mol Graph Model 2015 Sep 22;61:272-80. Epub 2015 Jul 22.

Department of Biosciences, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, Puttaparthy, 515134, Anantapur, Andhra Pradesh, India. Electronic address:

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http://dx.doi.org/10.1016/j.jmgm.2015.07.006DOI Listing
September 2015

CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-α-Gabpa and stress-induced adaptive responses via NF-κB-cMYC.

PLoS Genet 2015 Apr 1;11(4):e1005116. Epub 2015 Apr 1.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382186PMC
April 2015

Analytical strategies for studying stem cell metabolism.

Front Biol (Beijing) 2015 Apr;10(2):141-153

Program in Developmental Biology and Medical Scientist Training Program, Baylor College of Medicine; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030, USA ; Departments of Pediatrics-Neurology and Neuroscience, and Program in Structural and Computational Biology and Molecular Biophysics Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s11515-015-1357-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512307PMC
April 2015

Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate.

Cell 2014 Aug;158(4):916-928

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Computational and Integrative Biomedical Research Center, Baylor College of Medicine, Houston, TX 77030, USA; Verna and Marrs McLean Department of Biochemistry and Alkek Center for Molecular Discovery, Baylor College of Medicine, Houston, TX 77030, USA; Department of Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167585PMC
August 2014

Pathway-centric integrative analysis identifies RRM2 as a prognostic marker in breast cancer associated with poor survival and tamoxifen resistance.

Neoplasia 2014 May;16(5):390-402

Department of Molecular and Cell Biology, Baylor College of Medicine, Houston, TX, USA; Verna and Marrs McLean Department of Biochemistry, Baylor College of Medicine, Houston, TX, USA; Alkek Center for Molecular Discovery, Baylor College of Medicine, Houston, TX, USA; Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2014.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198742PMC
May 2014

Metabolomic profiling identifies biochemical pathways associated with castration-resistant prostate cancer.

J Proteome Res 2014 Feb 31;13(2):1088-100. Epub 2013 Dec 31.

Verna and Marrs McLean Department of Biochemistry and Molecular Biology, ‡Alkek Center for Molecular Discovery, §Molecular and Cellular Biology, and ∥Department of Surgery, Baylor College of Medicine , Houston, Texas 77030, United States.

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http://www.stat.berkeley.edu/~sumbose/drafts/kaushik_et_al_2
Web Search
http://pubs.acs.org/doi/abs/10.1021/pr401106h
Publisher Site
http://dx.doi.org/10.1021/pr401106hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975657PMC
February 2014

Application of 13C isotope labeling using liquid chromatography mass spectrometry (LC-MS) to determining phosphate-containing metabolic incorporation.

J Mass Spectrom 2013 Dec;48(12):1270-5

Department of Molecular and Cell Biology, Baylor College of Medicine, Houston, TX, 77030, USA; Alkek Center for Molecular Discovery, Baylor College of Medicine, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1002/jms.3292DOI Listing
December 2013

Pathway-directed weighted testing procedures for the integrative analysis of gene expression and metabolomic data.

Genomics 2012 May 2;99(5):265-74. Epub 2012 Apr 2.

Department of Public Health Sciences, Henry Ford Hospital, Detroit, MI, USA.

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http://dx.doi.org/10.1016/j.ygeno.2012.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525328PMC
May 2012

Novel role of androgens in mitochondrial fission and apoptosis.

Mol Cancer Res 2011 Aug 1;9(8):1067-77. Epub 2011 Jul 1.

Charlie Norwood VA Medical Center, Georgia Health Sciences University, Augusta, Georgia, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-10-0445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290867PMC
August 2011

Copper & biological health.

Indian J Med Res 2008 Oct;128(4):448-61

Department of Biosciences, Sri Sathya Sai University, Prasanthi Nilayam, India.

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October 2008

Humoral response profiling reveals pathways to prostate cancer progression.

Mol Cell Proteomics 2008 Mar 11;7(3):600-11. Epub 2007 Dec 11.

Michigan Center for Translational Pathology, Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.

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http://www.mcponline.org/lookup/doi/10.1074/mcp.M700263-MCP2
Publisher Site
http://dx.doi.org/10.1074/mcp.M700263-MCP200DOI Listing
March 2008

Differential phosphoprotein mapping in cancer cells using protein microarrays produced from 2-D liquid fractionation.

Anal Chem 2006 Feb;78(3):702-10

Department of Chemistry, University of Michigan, Ann Arbor, 48109, USA.

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http://dx.doi.org/10.1021/ac0511243DOI Listing
February 2006

Autoantibody signatures in prostate cancer.

N Engl J Med 2005 Sep;353(12):1224-35

Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1056/NEJMoa051931DOI Listing
September 2005

Serum antibodies to huntingtin interacting protein-1: a new blood test for prostate cancer.

Cancer Res 2005 May;65(10):4126-33

Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109-0942, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-4658DOI Listing
May 2005

Humoral immune response to alpha-methylacyl-CoA racemase and prostate cancer.

J Natl Cancer Inst 2004 Jun;96(11):834-43

Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109-0602, USA.

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http://dx.doi.org/10.1093/jnci/djh145DOI Listing
June 2004

Radiosensitization by pan ErbB inhibitor CI-1033 in vitro and in vivo.

Clin Cancer Res 2004 Jan;10(2):691-700

Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109-0010, USA.

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January 2004

Protein microarrays using liquid phase fractionation of cell lysates.

Proteomics 2003 Jul;3(7):1228-35

Department of Chemistry, University of Michigan, 930 N. University Avenue, Ann Arbor, MI 48109-1055, USA.

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http://dx.doi.org/10.1002/pmic.200300443DOI Listing
July 2003

Using protein microarrays to study cancer.

Biotechniques 2002 Dec;Suppl:46-53

Departments of Pathology and Urology, Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA.

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December 2002

Protein microarrays: a powerful tool to study cancer.

Curr Opin Mol Ther 2002 Dec;4(6):587-93

University of Michigan, 4237 Medical Science, 1301 Catherine Street, Ann Arbor, MI 48109, USA.

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December 2002

High and selective expression of yeast cytosine deaminase under a carcinoembryonic antigen promoter-enhancer.

Cancer Res 2002 Apr;62(8):2337-42

Department of Radiation Oncology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0010, USA.

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April 2002

Molecular cross-talk between the TRAIL and interferon signaling pathways.

J Biol Chem 2002 Jan 24;277(1):575-85. Epub 2001 Oct 24.

Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1074/jbc.M107795200DOI Listing
January 2002