Publications by authors named "Arun J Sanyal"

100Publications

Harnessing Muscle-Liver Crosstalk to Treat Nonalcoholic Steatohepatitis.

Front Endocrinol (Lausanne) 2020 23;11:592373. Epub 2020 Dec 23.

Department of Internal Medicine and Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Richmond, VA, United States.

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December 2020

A Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis.

N Engl J Med 2020 Nov 13. Epub 2020 Nov 13.

From the National Institute for Health Research Biomedical Research Centre at University Hospitals Birmingham NHS Foundation Trust and the Centre for Liver and Gastrointestinal Research, Institute of Immunology and Immunotherapy, University of Birmingham, and the Liver Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham (P.N.N.), and the Radcliffe Department of Medicine, University of Oxford, Oxford (S.A.H.) - all in the United Kingdom; Novo Nordisk, Søborg, Denmark (K.B., M.L., A.-S.S.); the Division of Endocrinology, Diabetes, and Metabolism, University of Florida, Gainesville (K.C.); the Department of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan (T.O.); the Institute of Cardiometabolism and Nutrition, Sorbonne Université, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, INSERM Unité Mixte de Recherche Scientifique 1138 Centre de Recherche des Cordeliers, Paris (V.R.); and the Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University School of Medicine, Richmond (A.J.S.).

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November 2020

Emerging roles of AATF: Checkpoint signaling and beyond.

J Cell Physiol 2020 Nov 4. Epub 2020 Nov 4.

Department of Biochemistry, CEMR, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India.

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November 2020

Nonalcoholic fatty liver disease: Reporting histologic findings in clinical practice.

Hepatology 2020 Oct 27. Epub 2020 Oct 27.

Medicine, Physiology and Molecular Pathology, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, 23284.

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October 2020

Drug discovery and treatment paradigms in nonalcoholic steatohepatitis.

Endocrinol Diabetes Metab 2020 Oct 10;3(4):e00105. Epub 2019 Dec 10.

Division of Gastroenterology, Hepatology and Nutrition Virginia Commonwealth University School of Medicine Richmond Virginia.

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October 2020

Changes in Serum Myostatin Levels in Alcoholic Hepatitis Correlate with Improvement in MELD.

Dig Dis Sci 2020 Oct 19. Epub 2020 Oct 19.

Division of Gastroenterology and Hepatology, Indiana University School of Medicine, 702 Rotary Circle, Suite 225, Indianapolis, IN, 46202, USA.

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October 2020

LPCN 1144 Resolves NAFLD in Hypogonadal Males.

Hepatol Commun 2020 Oct 2;4(10):1430-1440. Epub 2020 Aug 2.

Division of Gastroenterology, Hepatology and Nutrition Department of Internal Medicine Virginia Commonwealth University School of Medicine Richmond VA.

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October 2020

Association Between Lipoprotein Particles and Atherosclerotic Events in Nonalcoholic Fatty Liver Disease.

Clin Gastroenterol Hepatol 2020 Sep 30. Epub 2020 Sep 30.

Division of Gastroenterology and Hepatology, Hunter-Holmes McGuire Veterans Affairs Medical Center, Richmond, Virginia; Division of Gastroenterology and Hepatology, Virginia Commonwealth University Medical Center, Richmond, Virginia.

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September 2020

Safety, Tolerability, and Physiological Effects of AXA1665, a Novel Composition of Amino Acids, in Subjects With Child-Pugh A and B Cirrhosis.

Clin Transl Gastroenterol 2020 Aug;11(8):e00222

1Axcella Health Inc., Cambridge, Massachusetts, USA; 2Orange County Research Center, Tustin, California, USA; 3Flagship Pioneering, Cambridge, Massachusetts, USA; 4Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.

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August 2020

Clinical endpoints are necessary in the interim analysis of REGENERATE - Authors' reply.

Lancet 2020 09;396(10252):663-664

Virginia Commonwealth University, Richmond, VA 23298, USA. Electronic address:

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September 2020

The Fibrosis-4 Index Is Associated With Need for Mechanical Ventilation and 30-Day Mortality in Patients Admitted With Coronavirus Disease 2019.

J Infect Dis 2020 11;222(11):1794-1797

Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University, Richmond, Virginia, USA.

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November 2020

The Commensal Microbe Veillonella as a Marker for Response to an FGF19 Analog in NASH.

Hepatology 2020 Aug 13. Epub 2020 Aug 13.

Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA.

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August 2020

Increased hepatic and circulating chemokine and osteopontin expression occurs early in human NAFLD development.

PLoS One 2020 30;15(7):e0236353. Epub 2020 Jul 30.

Department of Medicine, University of Southern California (USC) Keck School of Medicine, Los Angeles, CA, United States of America.

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September 2020

Review article: the impact of liver-directed therapies on the atherogenic risk profile in non-alcoholic steatohepatitis.

Aliment Pharmacol Ther 2020 08 8;52(4):619-636. Epub 2020 Jul 8.

Division of Gastroenterology and Hepatology, Virginia Commonwealth University, Richmond, VA, USA.

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August 2020

Liver Transplant Is Associated with Sustained Improvement in Tandem Gait and Risk of Falls.

Dig Dis Sci 2020 Apr 22. Epub 2020 Apr 22.

Department of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, 1201 Broad Rock Boulevard, Richmond, VA, 23249, USA.

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April 2020

Immune Checkpoint Axes Are Dysregulated in Patients With Alcoholic Hepatitis.

Hepatol Commun 2020 Apr 12;4(4):588-605. Epub 2020 Jan 12.

Department of Microbiology and Immunology Indiana University School of Medicine Indianapolis IN.

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April 2020

Persistent Hyperactivation of Endothelial Cells in Patients with Alcoholic Hepatitis.

Alcohol Clin Exp Res 2020 05 21;44(5):1075-1087. Epub 2020 Apr 21.

Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana.

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May 2020

New drugs for non-alcoholic steatohepatitis.

Liver Int 2020 02;40 Suppl 1:96-101

Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.

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February 2020

Current management of non-alcoholic steatohepatitis.

Liver Int 2020 02;40 Suppl 1:89-95

Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.

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February 2020

MAFLD: A Consensus-Driven Proposed Nomenclature for Metabolic Associated Fatty Liver Disease.

Gastroenterology 2020 May 8;158(7):1999-2014.e1. Epub 2020 Feb 8.

Storr Liver Centre, Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, NSW, Australia. Electronic address:

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May 2020

Non-alcoholic fatty liver disease in lean individuals.

JHEP Rep 2019 Oct 30;1(4):329-341. Epub 2019 Aug 30.

Div. of Gastroenterology, Hepatology and Nutrition, Dept. of Internal Medicine, VCU School of Medicine, Richmond, VA 23298-0341.

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October 2019

Nonalcoholic Fatty Liver Disease.

Gastroenterol Clin North Am 2020 03;49(1):xiii-xiv

Department of Internal Medicine, Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University, Richmond, VA 23298-0341, USA. Electronic address:

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March 2020

Burden of Disease due to Nonalcoholic Fatty Liver Disease.

Gastroenterol Clin North Am 2020 03;49(1):1-23

Department of Internal Medicine, Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University School of Medicine, MCV Box 980341, Richmond, VA 23298-0341, USA. Electronic address:

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March 2020

Applying Non-Invasive Fibrosis Measurements in NAFLD/NASH: Progress to Date.

Pharmaceut Med 2019 12;33(6):451-463

Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University, Box 980341, Richmond, VA, 23298, USA.

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December 2019

Nonalcoholic Fatty Liver Disease and Fibrosis Associated With Increased Risk of Cardiovascular Events in a Prospective Study.

Clin Gastroenterol Hepatol 2020 Sep 27;18(10):2324-2331.e4. Epub 2019 Dec 27.

I Clinica Medica, Department of Clinical Internal, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.

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September 2020

The use of cell free DNA in the diagnosis of HCC.

Hepatoma Res 2019 23;5. Epub 2019 Sep 23.

Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA.

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September 2019

Role of gut microbiota in liver disease.

Am J Physiol Gastrointest Liver Physiol 2020 01 28;318(1):G84-G98. Epub 2019 Oct 28.

Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia.

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January 2020

Pathogenesis of NASH: The Impact of Multiple Pathways.

Curr Hepatol Rep 2018 Dec 31;17(4):350-360. Epub 2018 Oct 31.

Professor of Medicine, Physiology and Molecular Pathology, Division of Gastroenterology, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA.

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December 2018

Report on the AASLD/EASL joint workshop on clinical trial endpoints in NAFLD.

J Hepatol 2019 10 9;71(4):823-833. Epub 2019 Jul 9.

Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom.

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October 2019

Report on the AASLD/EASL Joint Workshop on Clinical Trial Endpoints in NAFLD.

Hepatology 2019 10 9;70(4):1424-1436. Epub 2019 Jul 9.

Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom.

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October 2019

REGENERATE: Design of a pivotal, randomised, phase 3 study evaluating the safety and efficacy of obeticholic acid in patients with fibrosis due to nonalcoholic steatohepatitis.

Contemp Clin Trials 2019 09 29;84:105803. Epub 2019 Jun 29.

Betty and Guy Beatty Center for Integrated Research, Inova Health System, Claude Moore Health Education and Research Building, 3300 Gallows Rd, Falls Church, VA, USA.

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September 2019

Clinical Characteristics and Outcomes of Mild to Moderate Alcoholic Hepatitis.

GastroHep 2019 Jul 14;1(4):161-165. Epub 2019 Jun 14.

Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.

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July 2019

Toward More Accurate Nomenclature for Fatty Liver Diseases.

Gastroenterology 2019 09 31;157(3):590-593. Epub 2019 May 31.

Storr Liver Centre, Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, Westmead, NSW, Australia. Electronic address:

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September 2019

FTY720/fingolimod decreases hepatic steatosis and expression of fatty acid synthase in diet-induced nonalcoholic fatty liver disease in mice.

J Lipid Res 2019 07 20;60(7):1311-1322. Epub 2019 May 20.

Department of Biochemistry and Molecular Biology Virginia Commonwealth University School of Medicine, Richmond, VA

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July 2019

Past, present and future perspectives in nonalcoholic fatty liver disease.

Authors:
Arun J Sanyal

Nat Rev Gastroenterol Hepatol 2019 06;16(6):377-386

Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, School of Medicine, Richmond, VA, USA.

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June 2019

Reduction in acute kidney injury stage predicts survival in patients with type-1 hepatorenal syndrome.

Nephrol Dial Transplant 2020 09;35(9):1554-1561

Scientific Affairs, Mallinckrodt Pharmaceuticals, Bedminster, NJ, USA.

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September 2020

Rifaximin has the potential to prevent complications of cirrhosis.

Therap Adv Gastroenterol 2018 28;11:1756284818800307. Epub 2018 Sep 28.

Virginia Commonwealth University, Richmond, VA, USA.

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September 2018

Putting non-alcoholic fatty liver disease on the radar for primary care physicians: how well are we doing?

Authors:
Arun J Sanyal

BMC Med 2018 08 24;16(1):148. Epub 2018 Aug 24.

Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, USA.

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August 2018

Posttraumatic Stress Disorder in Patients with Heavy Alcohol Consumption and Alcoholic Hepatitis.

Alcohol Clin Exp Res 2018 10 26;42(10):1933-1938. Epub 2018 Aug 26.

Department of Medicine , Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, Indiana.

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October 2018

Mechanisms of NAFLD development and therapeutic strategies.

Nat Med 2018 07 2;24(7):908-922. Epub 2018 Jul 2.

Division of Gastroenterology, Virginia Commonwealth University, Richmond, VA, USA.

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July 2018

Proton Pump Inhibitor Initiation and Withdrawal affects Gut Microbiota and Readmission Risk in Cirrhosis.

Am J Gastroenterol 2018 08 6;113(8):1177-1186. Epub 2018 Jun 6.

Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, VA, USA. Microbiology, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, VA, USA. Microbiome Analysis Center, George Mason University, Manassas, VA, USA.

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August 2018

Non-coding RNAs in Various Stages of Liver Disease Leading to Hepatocellular Carcinoma: Differential Expression of miRNAs, piRNAs, lncRNAs, circRNAs, and sno/mt-RNAs.

Sci Rep 2018 05 22;8(1):7967. Epub 2018 May 22.

Division of Plastic Surgery, Department of Surgery, Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA, 17033, USA.

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May 2018

Fatty liver in hepatitis C patients post-sustained virological response with direct-acting antivirals.

World J Gastroenterol 2018 Mar;24(11):1269-1277

California Liver Research Institute, Pasadena, CA 91105, United States.

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March 2018

Treatment of HCV in the Department of Corrections in the Era of Oral Medications.

J Correct Health Care 2018 04 22;24(2):127-136. Epub 2018 Mar 22.

1 Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University Health System, Richmond, VA, USA.

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April 2018

Reply.

Gastroenterology 2018 04 8;154(5):1546-1547. Epub 2018 Mar 8.

University of California Berkeley, Berkeley, California.

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April 2018

Future therapy for non-alcoholic fatty liver disease.

Liver Int 2018 Feb;38 Suppl 1:56-63

Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.

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February 2018

Translating scientific discovery: the need for preclinical models of nonalcoholic steatohepatitis.

Hepatol Int 2018 Jan 3;12(1):6-16. Epub 2018 Jan 3.

Division of Gastroenterology, Department of Medicine, VCU School of Medicine, MCV Box 980341, Richmond, VA, 23298-0341, USA.

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January 2018

Preclinical models of non-alcoholic fatty liver disease.

J Hepatol 2018 02 9;68(2):230-237. Epub 2017 Nov 9.

Div. of Gastroenterology, Hepatology and Nutrition, Dept. of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, United States. Electronic address:

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February 2018