Publications by authors named "Artitaya Lophatananon"

Are you Artitaya Lophatananon?   Register this Author

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
Nat Genet 2018 Jun 11. Epub 2018 Jun 11.
Institute of Cancer Research, London, UK.

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.
Nat Commun 2018 Jun 11;9(1):2256. Epub 2018 Jun 11.
The Institute of Cancer Research, London, SW7 3RP, UK.

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nat Genet 2018 May;50(5):765-766
Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nat Genet 2018 May;50(5):766-767
Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.
Nat Commun 2018 Apr 10;9:16193. Epub 2018 Apr 10.


Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nat Genet 2018 Jan 22;50(1):26-41. Epub 2017 Dec 22.
Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Reproductive profiles and risk of breast cancer subtypes: a multi-center case-only study.
Breast Cancer Res 2017 Nov 7;19(1):119. Epub 2017 Nov 7.
Department of Oncology, Leuven Multidisciplinary Breast Cancer, University Hospital Leuven, KU Leuven, Leuven, Belgium.


Development of a Cancer Risk Prediction Tool for Use in the UK Primary Care and Community Settings.
Cancer Prev Res (Phila) 2017 Jul 30;10(7):421-430. Epub 2017 May 30.
Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom.


Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation.
Am J Hum Genet 2016 Oct 15;99(4):903-911. Epub 2016 Sep 15.
Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia. Electronic address:

Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer.
Int J Cancer 2016 Sep 17;139(6):1303-1317. Epub 2016 Jun 17.
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA.

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.
Nat Commun 2016 Sep 7;7:12675. Epub 2016 Sep 7.
Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA.

Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry.
Cancer Causes Control 2016 May 6;27(5):679-93. Epub 2016 Apr 6.
Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, 2525 West End Avenue, 8th Floor, Nashville, TN, 37203-1738, USA.

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.
Nat Genet 2016 Apr 29;48(4):374-86. Epub 2016 Feb 29.
Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.

Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk.
Cancer Epidemiol Biomarkers Prev 2015 Nov 9;24(11):1680-91. Epub 2015 Sep 9.
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee.

Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression.
Am J Hum Genet 2015 Jul 11;97(1):22-34. Epub 2015 Jun 11.
Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia. Electronic address:

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.
Hum Mol Genet 2015 May 4;24(10):2966-84. Epub 2015 Feb 4.
Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.
Nat Genet 2015 Apr 9;47(4):373-80. Epub 2015 Mar 9.
1] Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. [2] Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk.
Hum Mol Genet 2015 Jan 28;24(1):285-98. Epub 2014 Aug 28.
Department of Oncology, University of Sheffield Medical School, Sheffield S10 2RX, UK

Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1.
Am J Hum Genet 2015 Jan 18;96(1):5-20. Epub 2014 Dec 18.
Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4029, Australia; School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, QLD 4072, Australia. Electronic address:

Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium.
Hum Mol Genet 2014 Nov 18;23(22):6096-111. Epub 2014 Jun 18.
Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.
Nat Commun 2014 Sep 23;4:4999. Epub 2014 Sep 23.
Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.

Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study.
Breast Cancer Res 2014 May 26;16(3):R51. Epub 2014 May 26.
Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, 237 Fulham Road, London, SW3 6JB, UK.

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.
Am J Hum Genet 2013 Dec 27;93(6):1046-60. Epub 2013 Nov 27.
CRUK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK. Electronic address:



Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
Nat Genet 2013 Apr;45(4):353-61, 361e1-2
Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.
Nat Genet 2013 Apr;45(4):371-84, 384e1-2
Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark.

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
Nat Genet 2013 Apr;45(4):385-91, 391e1-2
The Institute of Cancer Research, Sutton, UK.

Genome-wide association studies identify four ER negative-specific breast cancer risk loci.
Nat Genet 2013 Apr;45(4):392-8, 398e1-2
1] Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK. [2] Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK. [3].

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers.
Am J Hum Genet 2013 Apr 27;92(4):489-503. Epub 2013 Mar 27.
School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia.

9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium.
Cancer Epidemiol Biomarkers Prev 2012 Oct 2;21(10):1783-91. Epub 2012 Aug 2.
Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, United Kingdom.

11q13 is a susceptibility locus for hormone receptor positive breast cancer.
Hum Mutat 2012 Jul 30;33(7):1123-32. Epub 2012 Apr 30.
Vesalius Research Center, VIB, KU Leuven, Leuven, Belgium.

19p13.1 is a triple-negative-specific breast cancer susceptibility locus.
Cancer Res 2012 Apr 13;72(7):1795-803. Epub 2012 Feb 13.
Departments of Health Sciences Research and Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA.

Genome-wide association analysis identifies three new breast cancer susceptibility loci.
Nat Genet 2012 Jan 22;44(3):312-8. Epub 2012 Jan 22.
Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, UK.





Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.
Nat Genet 2009 Oct 20;41(10):1116-21. Epub 2009 Sep 20.
The Institute of Cancer Research, Sutton, Surrey, UK.











Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC).
PLoS One 2012 7;7(8):e42380. Epub 2012 Aug 7.
Unit of Genetic Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany.

Trends and outcome from radical therapy for primary non-metastatic prostate cancer in a UK population.
PLoS One 2015 5;10(3):e0119494. Epub 2015 Mar 5.
Academic Urology Group, Department of Surgery & Oncology, University of Cambridge, Cambridge, United Kingdom; Translational Prostate Cancer Group, Hutchison/MRC Research centre, University of Cambridge, Cambridge, United Kingdom.

No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing.
J Med Genet 2016 05 26;53(5):298-309. Epub 2016 Feb 26.
Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia.

An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression.
Hum Mol Genet 2016 09 11;25(17):3863-3876. Epub 2016 Jul 11.
Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA

Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus.
Breast Cancer Res 2016 06 21;18(1):64. Epub 2016 Jun 21.
Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, 2525 West End Avenue, 8th Floor, Nashville, TN, 37203-1738, USA.

Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus.
PLoS One 2016 24;11(8):e0160316. Epub 2016 Aug 24.
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, United States of America.

Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).
Sci Rep 2016 09 7;6:32512. Epub 2016 Sep 7.
Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.

rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk.
Sci Rep 2016 11 15;6:36874. Epub 2016 Nov 15.
Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.


Rare and low-frequency coding variants alter human adult height.
Nature 2017 02 1;542(7640):186-190. Epub 2017 Feb 1.
Montreal Heart Institute, Montreal, Quebec H1T 1C8, Canada.

Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer.
Cancer Res 2017 06 10;77(11):2789-2799. Epub 2017 Mar 10.
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.