Arthur I Skoultchi

Arthur I Skoultchi

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Arthur I Skoultchi

Arthur I Skoultchi

Publications by authors named "Arthur I Skoultchi"

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51Publications

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The chromatin remodeler Snf2h is essential for oocyte meiotic cell cycle progression.

Genes Dev 2020 02 9;34(3-4):166-178. Epub 2020 Jan 9.

Howard Hughes Medical Institute, Boston Children's Hospital, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1101/gad.331157.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000916PMC
February 2020

Runx1 promotes murine erythroid progenitor proliferation and inhibits differentiation by preventing Pu.1 downregulation.

Proc Natl Acad Sci U S A 2019 09 20;116(36):17841-17847. Epub 2019 Aug 20.

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461;

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http://dx.doi.org/10.1073/pnas.1901122116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731665PMC
September 2019

ISWI ATPase Smarca5 Regulates Differentiation of Thymocytes Undergoing β-Selection.

J Immunol 2019 06 8;202(12):3434-3446. Epub 2019 May 8.

BIOCEV, First Faculty of Medicine, Charles University, Vestec 25250, Czech Republic;

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http://dx.doi.org/10.4049/jimmunol.1801684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548592PMC
June 2019

Bidirectional Analysis of Cryba4-Crybb1 Nascent Transcription and Nuclear Accumulation of Crybb3 mRNAs in Lens Fibers.

Invest Ophthalmol Vis Sci 2019 01;60(1):234-244

Departments of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States.

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http://dx.doi.org/10.1167/iovs.18-25921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336207PMC
January 2019

Emerging roles of linker histones in regulating chromatin structure and function.

Nat Rev Mol Cell Biol 2018 03 11;19(3):192-206. Epub 2017 Oct 11.

Laboratory of Biochemistry and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/nrm.2017.94DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897046PMC
March 2018

BEN domain protein Elba2 can functionally substitute for linker histone H1 in Drosophila in vivo.

Sci Rep 2016 Sep 30;6:34354. Epub 2016 Sep 30.

Albert Einstein College of Medicine, Department of Cell Biology, Bronx, NY 10461, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043383PMC
http://dx.doi.org/10.1038/srep34354DOI Listing
September 2016

Independent Biological and Biochemical Functions for Individual Structural Domains of Drosophila Linker Histone H1.

J Biol Chem 2016 07 18;291(29):15143-55. Epub 2016 May 18.

From the Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York 10461

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http://dx.doi.org/10.1074/jbc.M116.730705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946930PMC
July 2016

The role of H1 linker histone subtypes in preserving the fidelity of elaboration of mesendodermal and neuroectodermal lineages during embryonic development.

PLoS One 2014 6;9(5):e96858. Epub 2014 May 6.

Roslyn and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, New York, United States of America; Institute for Brain Disorders and Neural Regeneration, Albert Einstein College of Medicine, Bronx, New York, United States of America; Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, United States of America; Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York, United States of America; Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, New York, United States of America; Rose F. Kennedy Center for Research on Intellectual and Developmental Disabilities, Albert Einstein College of Medicine, Bronx, New York, United States of America; Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, New York, United States of America; Ruth L. and David S. Gottesman Institute for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, New York, United States of America; Center for Epigenomics, Albert Einstein College of Medicine, Bronx, New York, United States of America; Institute for Aging Research, Albert Einstein College of Medicine, Bronx, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0096858PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011883PMC
June 2015

Drosophila linker histone H1 coordinates STAT-dependent organization of heterochromatin and suppresses tumorigenesis caused by hyperactive JAK-STAT signaling.

Epigenetics Chromatin 2014 28;7:16. Epub 2014 Jul 28.

Department of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1186/1756-8935-7-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149798PMC
September 2014

Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation.

Nat Commun 2014 Jun 20;5:4181. Epub 2014 Jun 20.

1] Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada K1H 8L6 [2] Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada K1H 8M5 [3] Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada K1H 8M5.

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http://dx.doi.org/10.1038/ncomms5181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083431PMC
June 2014

H1 linker histone promotes epigenetic silencing by regulating both DNA methylation and histone H3 methylation.

Proc Natl Acad Sci U S A 2013 Jan 9;110(5):1708-13. Epub 2013 Jan 9.

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1073/pnas.1213266110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562819PMC
January 2013

GATA-1 directly regulates p21 gene expression during erythroid differentiation.

Cell Cycle 2010 May 15;9(10):1972-80. Epub 2010 May 15.

1Department of Cell Biology, Montefiore Medical Center, Bronx, NY, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019278PMC
http://dx.doi.org/10.4161/cc.9.10.11602DOI Listing
May 2010

PU.1 directly regulates cdk6 gene expression, linking the cell proliferation and differentiation programs in erythroid cells.

J Biol Chem 2010 Jan 2;285(5):3044-52. Epub 2009 Dec 2.

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1074/jbc.M109.077727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823399PMC
January 2010

PU.1 activation relieves GATA-1-mediated repression of Cebpa and Cbfb during leukemia differentiation.

Mol Cancer Res 2009 Oct 13;7(10):1693-703. Epub 2009 Oct 13.

Institute of Pathological Physiology and Center of Experimental Hematology, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1158/1541-7786.MCR-09-0031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193075PMC
October 2009

Nuclear localization of ISWI ATPase Smarca5 (Snf2h) in mouse.

Front Biosci (Elite Ed) 2009 Jun 1;1:553-9. Epub 2009 Jun 1.

Pathological Physiology and Center of Experimental Hematology, First Faculty of Medicine, Charles University, Prague, Czech Republic.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556728PMC
http://dx.doi.org/10.2741/e53DOI Listing
June 2009

CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis.

Nat Cell Biol 2009 Feb 18;11(2):172-82. Epub 2009 Jan 18.

Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1038/ncb1831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132516PMC
February 2009

Reprogramming leukemia cells to terminal differentiation and growth arrest by RNA interference of PU.1.

Mol Cancer Res 2007 Oct;5(10):1053-62

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-07-0145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190309PMC
October 2007

Global chromatin compaction limits the strength of the DNA damage response.

J Cell Biol 2007 Sep;178(7):1101-8

Genomic Instability Group, Molecular Oncology Programme, Spanish National Cancer Center, Madrid 28029, Spain.

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http://dx.doi.org/10.1083/jcb.200704140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064646PMC
September 2007

Behavior of mice with mutations in the conserved region deleted in velocardiofacial/DiGeorge syndrome.

Neurogenetics 2006 Nov 10;7(4):247-57. Epub 2006 Aug 10.

Department of Medicine, University of California, San Diego School of Medicine, La Jolla, CA 92093-0627, USA.

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http://dx.doi.org/10.1007/s10048-006-0054-0DOI Listing
November 2006

Role of linker histone in chromatin structure and function: H1 stoichiometry and nucleosome repeat length.

Chromosome Res 2006 ;14(1):17-25

Biology Department and Program in Molecular and Cellular Biology, University of Massachusetts, Amherst, 01003, USA.

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http://dx.doi.org/10.1007/s10577-005-1024-3DOI Listing
May 2006

PU.1 inhibits the erythroid program by binding to GATA-1 on DNA and creating a repressive chromatin structure.

EMBO J 2005 Nov 13;24(21):3712-23. Epub 2005 Oct 13.

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY, USA.

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http://dx.doi.org/10.1038/sj.emboj.7600834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1276718PMC
November 2005

MAPK-mediated phosphorylation of GATA-1 promotes Bcl-XL expression and cell survival.

J Biol Chem 2005 Aug 20;280(33):29533-42. Epub 2005 Jun 20.

Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.

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http://dx.doi.org/10.1074/jbc.M506514200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193074PMC
August 2005

Reductions in linker histone levels are tolerated in developing spermatocytes but cause changes in specific gene expression.

J Biol Chem 2004 May 23;279(22):23525-35. Epub 2004 Mar 23.

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1074/jbc.M400925200DOI Listing
May 2004

Genetic analysis of H1 linker histone subtypes and their functions in mice.

Methods Enzymol 2004 ;377:85-107

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1016/S0076-6879(03)77005-0DOI Listing
April 2004

PU.1 and pRB interact and cooperate to repress GATA-1 and block erythroid differentiation.

Mol Cell Biol 2003 Nov;23(21):7460-74

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC207581PMC
http://dx.doi.org/10.1128/mcb.23.21.7460-7474.2003DOI Listing
November 2003

The ISWI ATPase Snf2h is required for early mouse development.

Proc Natl Acad Sci U S A 2003 Nov 14;100(24):14097-102. Epub 2003 Nov 14.

Department of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1073/pnas.2336105100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC283552PMC
November 2003

Reversal of tumorigenicity and the block to differentiation in erythroleukemia cells by GATA-1.

Cancer Res 2003 Oct;63(19):6363-9

Department of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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October 2003

Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks.

Cell 2003 Sep;114(6):673-88

Department of Post-Genomics and Diseases, Osaka University Medical School, 2-2 Yamadaoka, Suita, 565-0871, Osaka, Japan.

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http://dx.doi.org/10.1016/s0092-8674(03)00719-0DOI Listing
September 2003

CDK6 blocks differentiation: coupling cell proliferation to the block to differentiation in leukemic cells.

Oncogene 2003 Jul;22(27):4143-9

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1038/sj.onc.1206484DOI Listing
July 2003

Mouse oocytes and early embryos express multiple histone H1 subtypes.

Biol Reprod 2003 May 11;68(5):1569-76. Epub 2002 Dec 11.

Department of Obstetrics and Gynecology, McGill University, Montréal, Québec, Canada.

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http://dx.doi.org/10.1095/biolreprod.102.012336DOI Listing
May 2003

Mammalian linker-histone subtypes differentially affect gene expression in vivo.

Proc Natl Acad Sci U S A 2003 May 28;100(10):5920-5. Epub 2003 Apr 28.

Department of Medicine, Division of Hematology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1073/pnas.0736105100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC156302PMC
May 2003