Arthur D Riggs

Arthur D Riggs

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Arthur D Riggs

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Elimination of human folypolyglutamate synthetase alters programming and plasticity of somatic cells.

FASEB J 2019 Oct 4:fj201901721R. Epub 2019 Oct 4.

Department of Diabetes Complications and Metabolism, City of Hope National Medical Center, Duarte, California, USA.

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http://dx.doi.org/10.1096/fj.201901721RDOI Listing
October 2019

SMC1A is associated with radioresistance in prostate cancer and acts by regulating epithelial-mesenchymal transition and cancer stem-like properties.

Mol Carcinog 2019 01 5;58(1):113-125. Epub 2018 Oct 5.

Department of Molecular Medicine, City of Hope National Medical Center, Duarte, California.

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http://doi.wiley.com/10.1002/mc.22913
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http://dx.doi.org/10.1002/mc.22913DOI Listing
January 2019

Frequent monoallelic or skewed expression for developmental genes in CNS-derived cells and evidence for balancing selection.

Proc Natl Acad Sci U S A 2018 10 15;115(44):E10379-E10386. Epub 2018 Oct 15.

Diabetes and Metabolism Research Institute, City of Hope Comprehensive Cancer Center, Duarte, CA 91010;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1808652115
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http://dx.doi.org/10.1073/pnas.1808652115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217436PMC
October 2018

GFAP Mutations in Astrocytes Impair Oligodendrocyte Progenitor Proliferation and Myelination in an hiPSC Model of Alexander Disease.

Cell Stem Cell 2018 Aug;23(2):239-251.e6

Division of Stem Cell Biology Research, Department of Developmental and Stem Cell Biology, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA; Irell and Manella Graduate School of Biological Sciences, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2018.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230521PMC
August 2018

Differences in silencing of mismatched targets by sliced versus diced siRNAs.

Nucleic Acids Res 2018 07;46(13):6806-6822

Department of Diabetes Complications & Metabolism, Diabetes and Metabolism Research Institute, Beckman Research Institute of City of Hope, 1500 E. Duarte Road, Duarte, CA 91010-3000, USA.

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http://dx.doi.org/10.1093/nar/gky287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061797PMC
July 2018

MHC-mismatched mixed chimerism restores peripheral tolerance of noncross-reactive autoreactive T cells in NOD mice.

Proc Natl Acad Sci U S A 2018 03 20;115(10):E2329-E2337. Epub 2018 Feb 20.

Diabetes and Metabolism Research Institute, The Beckman Research Institute of City of Hope, Duarte, CA 91010;

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http://dx.doi.org/10.1073/pnas.1720169115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877958PMC
March 2018

Analysis of high-resolution 3D intrachromosomal interactions aided by Bayesian network modeling.

Proc Natl Acad Sci U S A 2017 11 13;114(48):E10359-E10368. Epub 2017 Nov 13.

Department of Diabetes Complications and Metabolism, Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA

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http://dx.doi.org/10.1073/pnas.1620425114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715735PMC
November 2017

SAIC: an iterative clustering approach for analysis of single cell RNA-seq data.

BMC Genomics 2017 Oct 3;18(Suppl 6):689. Epub 2017 Oct 3.

Integrative Genomics Core, Beckman Research Institute, City of Hope, Duarte, CA, 91010, USA.

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http://dx.doi.org/10.1186/s12864-017-4019-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629617PMC
October 2017

A Simple and Cost-Effective Approach for In Vitro Production of Sliced siRNAs as Potent Triggers for RNAi.

Mol Ther Nucleic Acids 2017 Sep 13;8:345-355. Epub 2017 Jul 13.

Department of Diabetes Complications & Metabolism, Diabetes & Metabolism Research Institute, Beckman Research Institute, City of Hope, 1500 E. Duarte Road, Duarte, CA 91010, USA. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2017.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537206PMC
September 2017

mA RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells.

Cell Rep 2017 03;18(11):2622-2634

Division of Stem Cell Biology Research, Department of Developmental and Stem Cell Biology, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA; Irell and Manella Graduate School of Biological Sciences, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.02.059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479356PMC
March 2017

Small-Molecule-Based Lineage Reprogramming Creates Functional Astrocytes.

Cell Rep 2016 07 7;16(3):781-92. Epub 2016 Jul 7.

Division of Stem Cell Biology Research, Department of Developmental and Stem Cell Biology, Beckman Research Institute of City of Hope, 1500 E. Duarte Road, Duarte, CA 91010, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.06.042DOI Listing
July 2016

The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model.

Nat Commun 2016 Mar 11;7:10965. Epub 2016 Mar 11.

Division of Stem Cell Biology Research, Department of Developmental and Stem Cell Biology, Cancer Center, Beckman Research Institute of City of Hope, 1500 E. Duarte Road, Duarte, California 91010, USA.

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http://dx.doi.org/10.1038/ncomms10965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793043PMC
March 2016

Downregulation of TLX induces TET3 expression and inhibits glioblastoma stem cell self-renewal and tumorigenesis.

Nat Commun 2016 Feb 3;7:10637. Epub 2016 Feb 3.

Department of Developmental and Stem Cell Biology, Division of Stem Cell Biology Research, Cancer Center, Beckman Research Institute of City of Hope, 1500 E. Duarte Road, Duarte, California 91010, USA.

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http://dx.doi.org/10.1038/ncomms10637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742843PMC
February 2016

Mapping Human Pluripotent-to-Cardiomyocyte Differentiation: Methylomes, Transcriptomes, and Exon DNA Methylation "Memories".

EBioMedicine 2016 Feb 19;4:74-85. Epub 2016 Jan 19.

Department of Diabetes Complications and Metabolism, Duarte, CA 91010, USA; Beckman Research Institute at City of Hope National Medical Center, Duarte, CA 91010, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S23523964163001
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http://dx.doi.org/10.1016/j.ebiom.2016.01.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776252PMC
February 2016

Cells with surface expression of CD133highCD71low are enriched for tripotent colony-forming progenitor cells in the adult murine pancreas.

Stem Cell Res 2016 Jan 30;16(1):40-53. Epub 2015 Nov 30.

Department of Translational Research and Cellular Therapeutics, Diabetes and Metabolism Research Institute, Duarte, CA 91010, United States; Irell & Manella Graduate School of Biological Sciences, Duarte, CA 91010, United States; Beckman Research Institute of City of Hope, Duarte, CA 91010, United States. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2015.11.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762724PMC
January 2016

Growth factors and medium hyperglycemia induce Sox9+ ductal cell differentiation into β cells in mice with reversal of diabetes.

Proc Natl Acad Sci U S A 2016 Jan 5;113(3):650-5. Epub 2016 Jan 5.

Diabetes and Metabolism Research Institute and Beckman Research Institute, City of Hope, Duarte, CA 91010;

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http://dx.doi.org/10.1073/pnas.1524200113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725504PMC
January 2016

MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.

Proc Natl Acad Sci U S A 2015 Dec 8;112(52):15994-9. Epub 2015 Dec 8.

Diabetes and Metabolism Research Institute and Beckman Research Institute of City of Hope, Duarte, CA 91010;

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http://dx.doi.org/10.1073/pnas.1521157112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702961PMC
December 2015

Postnatal Pancreas of Mice Contains Tripotent Progenitors Capable of Giving Rise to Duct, Acinar, and Endocrine Cells In Vitro.

Stem Cells Dev 2015 Sep 9;24(17):1995-2008. Epub 2015 Jun 9.

1 Irell & Manella Graduate School of Biological Sciences, Diabetes & Metabolism Research Institute at City of Hope , Duarte, California.

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https://www.liebertpub.com/doi/10.1089/scd.2015.0007
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http://dx.doi.org/10.1089/scd.2015.0007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545527PMC
September 2015

In vitro multilineage differentiation and self-renewal of single pancreatic colony-forming cells from adult C57BL/6 mice.

Stem Cells Dev 2014 Apr 4;23(8):899-909. Epub 2014 Jan 4.

1 Department of Diabetes and Metabolic Diseases Research, Beckman Research Institute of City of Hope , Duarte, California.

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http://dx.doi.org/10.1089/scd.2013.0466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991994PMC
April 2014

Enhanced evolution by stochastically variable modification of epigenetic marks in the early embryo.

Proc Natl Acad Sci U S A 2014 Apr 14;111(17):6353-8. Epub 2014 Apr 14.

Department of Diabetes and Metabolic Diseases Research, Beckman Research Institute of the City of Hope, Duarte, CA 91010.

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http://dx.doi.org/10.1073/pnas.1402585111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035958PMC
April 2014

MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation.

Proc Natl Acad Sci U S A 2013 Oct 10;110(44):17892-7. Epub 2013 Oct 10.

Department of Diabetes and Metabolic Diseases Research, The Irell and Manella Graduate School of Biological Sciences, and Transgenic Mouse Core, Beckman Research Institute of City of Hope, Duarte, CA 91010.

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http://dx.doi.org/10.1073/pnas.1317397110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816405PMC
October 2013

Regulation of adipose tissue T cell subsets by Stat3 is crucial for diet-induced obesity and insulin resistance.

Proc Natl Acad Sci U S A 2013 Aug 22;110(32):13079-84. Epub 2013 Jul 22.

Department of Cancer Immunotherapeutics and Tumor Immunology, Beckman Research Institute, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1073/pnas.1311557110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740863PMC
August 2013

COHCAP: an integrative genomic pipeline for single-nucleotide resolution DNA methylation analysis.

Nucleic Acids Res 2013 Jun 17;41(11):e117. Epub 2013 Apr 17.

Bioinformatics Core, City of Hope National Medical Center, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1093/nar/gkt242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675470PMC
June 2013

The histone methyltransferase KMT2B is required for RNA polymerase II association and protection from DNA methylation at the MagohB CpG island promoter.

Mol Cell Biol 2013 Apr 28;33(7):1383-93. Epub 2013 Jan 28.

School of Cancer Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.

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http://mcb.asm.org/content/early/2013/01/25/MCB.01721-12.ful
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http://mcb.asm.org/cgi/doi/10.1128/MCB.01721-12
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http://dx.doi.org/10.1128/MCB.01721-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624271PMC
April 2013

Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel.

Proc Natl Acad Sci U S A 2013 Mar 19;110(10):3907-12. Epub 2013 Feb 19.

Department of Diabetes and Metabolic Diseases Research, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1073/pnas.1301889110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593860PMC
March 2013

Identification of Oct4-activating compounds that enhance reprogramming efficiency.

Proc Natl Acad Sci U S A 2012 Dec 3;109(51):20853-8. Epub 2012 Dec 3.

Department of Neurosciences, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1219181110
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http://dx.doi.org/10.1073/pnas.1219181110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529047PMC
December 2012

Epigenetic stability, adaptability, and reversibility in human embryonic stem cells.

Proc Natl Acad Sci U S A 2012 Jul 16;109(31):12544-9. Epub 2012 Jul 16.

Department of Biology, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1073/pnas.1209620109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411986PMC
July 2012

Inhibition of S-phase kinase-associated protein 2 (Skp2) reprograms and converts diabetogenic T cells to Foxp3+ regulatory T cells.

Proc Natl Acad Sci U S A 2012 Jun 29;109(24):9493-8. Epub 2012 May 29.

Department of Diabetes and Metabolic Diseases, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1073/pnas.1207293109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386130PMC
June 2012

Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation.

Proc Natl Acad Sci U S A 2012 May 30;109(20):7765-9. Epub 2012 Apr 30.

Department of Cancer Immunotherapeutics and Tumor Immunology, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1073/pnas.1205132109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356652PMC
May 2012

DNA methylation biomarkers for lung cancer.

Tumour Biol 2012 Apr 6;33(2):287-96. Epub 2011 Dec 6.

Division of Biology, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1007/s13277-011-0282-2DOI Listing
April 2012

DNA methylation and demethylation in mammals.

J Biol Chem 2011 May 24;286(21):18347-53. Epub 2011 Mar 24.

Division of Biology, Beckman Research Institute of the City of Hope, Duarte, California 91010, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.R110.205286
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http://dx.doi.org/10.1074/jbc.R110.205286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099650PMC
May 2011

Killer cell Ig-like receptor (KIR) 3DL1 down-regulation enhances inhibition of type 1 diabetes by autoantigen-specific regulatory T cells.

Proc Natl Acad Sci U S A 2011 Feb 18;108(5):2016-21. Epub 2011 Jan 18.

Department of Immunology, Diabetes and Metabolic Disease Research, The Beckman Research Institute of the City of Hope, Duarte, CA 91010-3000, USA.

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http://www.pnas.org/lookup/doi/10.1073/pnas.1019082108
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http://dx.doi.org/10.1073/pnas.1019082108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033262PMC
February 2011

CpG island clusters and pro-epigenetic selection for CpGs in protein-coding exons of HOX and other transcription factors.

Proc Natl Acad Sci U S A 2010 Aug 17;107(35):15485-90. Epub 2010 Aug 17.

Department of Molecular and Cellular Biology, Division of Biology, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1073/pnas.1010506107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932574PMC
August 2010

CRM1 mediates nuclear-cytoplasmic shuttling of mature microRNAs.

Proc Natl Acad Sci U S A 2009 Dec 2;106(51):21655-9. Epub 2009 Dec 2.

Department of Molecular and Cellular Biology, Beckman Research Institute of the City of Hope, 1450 East Duarte Road, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1073/pnas.0912384106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787469PMC
December 2009

Analysis of RNA structure and RNA-protein interactions in mammalian cells by use of terminal transferase-dependent PCR.

Methods Mol Biol 2008 ;488:319-41

Beckman Research Institute of the City of Hope, Duarte, California, USA.

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http://link.springer.com/10.1007/978-1-60327-475-3_21
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http://dx.doi.org/10.1007/978-1-60327-475-3_21DOI Listing
January 2009

A human B cell methylome at 100-base pair resolution.

Proc Natl Acad Sci U S A 2009 Jan 12;106(3):671-8. Epub 2009 Jan 12.

Department of Biology, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1073/pnas.0812399106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621253PMC
January 2009

Methylation of polycomb target genes in intestinal cancer is mediated by inflammation.

Cancer Res 2008 Dec;68(24):10280-9

Division of Biology, Beckman Research Institute of the City of Hope, Duarte, California 91010, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-1957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491345PMC
December 2008

X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations.

Proc Natl Acad Sci U S A 2008 Mar 13;105(12):4709-14. Epub 2008 Mar 13.

Department of Human Genetics, Geffen School of Medicine, and Departments of Pathology and Laboratory Medicine and Molecular Cell and Developmental Biology, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1073/pnas.0712018105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290804PMC
March 2008

Histone methylation patterns are cell-type specific in human monocytes and lymphocytes and well maintained at core genes.

J Immunol 2008 Feb;180(4):2264-9

Department of Diabetes, Beckman Research Institute of City of Hope, 1500 East Duarte Road, Duarte, CA 91010, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683787PMC
http://dx.doi.org/10.4049/jimmunol.180.4.2264DOI Listing
February 2008

High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer.

Proc Natl Acad Sci U S A 2008 Jan 27;105(1):252-7. Epub 2007 Dec 27.

Divisions of Biology, Information Sciences, and Surgery, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1073/pnas.0710735105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224196PMC
January 2008

Methylated-CpG island recovery assay-assisted microarrays for cancer diagnosis.

Expert Opin Med Diagn 2007 Sep;1(1):99-108

Beckman Research Institute of the City of Hope, Division of Biology, Duarte, CA 91010, USA +1 626 301 8853 ; +1 626 358 7703 ;

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http://dx.doi.org/10.1517/17530059.1.1.99DOI Listing
September 2007

Nucleotide excision repair eliminates unique DNA-protein cross-links from mammalian cells.

J Biol Chem 2007 Aug 16;282(31):22592-604. Epub 2007 May 16.

Biology Division, Beckman Research Institute, City of Hope National Medical Center, Duarte, California 91010, USA.

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http://dx.doi.org/10.1074/jbc.M702856200DOI Listing
August 2007

Riggs AD Co-Editor-in-Chief.

Authors:
Arthur D Riggs

Biosci Trends 2007 Aug;1(1)

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August 2007

Genome-wide analysis of histone lysine methylation variations caused by diabetic conditions in human monocytes.

J Biol Chem 2007 May 5;282(18):13854-63. Epub 2007 Mar 5.

Department of Diabetes, Beckman Research Institute of City of Hope, Duarte, California 91010, USA.

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http://dx.doi.org/10.1074/jbc.M609446200DOI Listing
May 2007

Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay.

Proc Natl Acad Sci U S A 2007 Mar 16;104(13):5527-32. Epub 2007 Mar 16.

Division of Biology, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1073/pnas.0701059104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838508PMC
March 2007

The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells.

J Biol Chem 2006 Jul 8;281(28):19489-500. Epub 2006 May 8.

Division of Biology, Beckman Research Institute, City of Hope, Duarte, California 91010, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M513249200
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http://dx.doi.org/10.1074/jbc.M513249200DOI Listing
July 2006

Mutations in DNA methyltransferase DNMT3B in ICF syndrome affect its regulation by DNMT3L.

Hum Mol Genet 2006 May 16;15(9):1375-85. Epub 2006 Mar 16.

The State Key Laboratory of Molecular Biology, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, China.

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http://dx.doi.org/10.1093/hmg/ddl059DOI Listing
May 2006

The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells.

RNA 2006 Feb 22;12(2):256-62. Epub 2005 Dec 22.

Department of Molecular Medicine and Hematology, University of the Witwatersrand Medical School, Parktown, South Africa.

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http://dx.doi.org/10.1261/rna.2235106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1370905PMC
February 2006

Inhibition of Atm and/or Atr disrupts gene silencing on the inactive X chromosome.

Biochem Biophys Res Commun 2005 Nov 29;337(3):875-80. Epub 2005 Sep 29.

Department of Human Genetics, The David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.bbrc.2005.09.122DOI Listing
November 2005

Repositioning-dependent fate of duplicate genes.

DNA Cell Biol 2005 Sep;24(9):529-42

Theoretical Biology Department, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1089/dna.2005.24.529DOI Listing
September 2005

Physical and functional interactions between the human DNMT3L protein and members of the de novo methyltransferase family.

J Cell Biochem 2005 Aug;95(5):902-17

Division of Biology, Beckman Research Institute of the City of Hope, Duarte, California 91010, USA.

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http://dx.doi.org/10.1002/jcb.20447DOI Listing
August 2005

Maintenance and regulation of DNA methylation patterns in mammals.

Biochem Cell Biol 2005 Aug;83(4):438-48

Division of Biology, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1139/o05-138DOI Listing
August 2005

DNA lesions induced by UV A1 and B radiation in human cells: comparative analyses in the overall genome and in the p53 tumor suppressor gene.

Proc Natl Acad Sci U S A 2005 Jul 11;102(29):10058-63. Epub 2005 Jul 11.

Division of Biology, Beckman Research Institute, and Department of Medical Oncology, The City of Hope National Medical Center, 1450 East Duarte Road, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1073/pnas.0502311102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174921PMC
July 2005

HnRNP H inhibits nuclear export of mRNA containing expanded CUG repeats and a distal branch point sequence.

Nucleic Acids Res 2005 15;33(12):3866-74. Epub 2005 Jul 15.

Department of Molecular Biology, Beckman Research Institute of the City of Hope Duarte, CA, USA.

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http://dx.doi.org/10.1093/nar/gki698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1176012PMC
July 2005

Rapid, solid-phase based automated analysis of chromatin structure and transcription factor occupancy in living eukaryotic cells.

Nucleic Acids Res 2005 Jan 11;33(1):e1. Epub 2005 Jan 11.

Molecular Medicine Unit, University of Leeds, St James's University Hospital Leeds LS9 7TF, UK.

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http://dx.doi.org/10.1093/nar/gni001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC546173PMC
January 2005

In vivo detection of ribozyme cleavage products and RNA structure by use of terminal transferase-dependent PCR.

Methods Mol Biol 2004 ;252:109-24

Department of Biology and Molecular Biology, Beckman Research Institute of the City of Hope, Duarte, CA, USA.

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http://dx.doi.org/10.1385/1-59259-746-7:109DOI Listing
June 2004

Methylation and epigenetic fidelity.

Proc Natl Acad Sci U S A 2004 Jan 26;101(1):4-5. Epub 2003 Dec 26.

Division of Biology, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1073/pnas.0307781100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC314126PMC
January 2004

High concentrations of long interspersed nuclear element sequence distinguish monoallelically expressed genes.

Proc Natl Acad Sci U S A 2003 Aug 8;100(17):9940-5. Epub 2003 Aug 8.

Department of Human Genetics, University of California, Los Angeles, CA 90095, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1737401100
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http://dx.doi.org/10.1073/pnas.1737401100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC187893PMC
August 2003

Epigenetic silencing may aid evolution by gene duplication.

J Mol Evol 2003 Jun;56(6):718-29

Theoretical Biology Department, Beckman Research Institute of the City of Hope, 1500 East Duarte Road, Duarte, CA 91010-3000, USA.

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http://dx.doi.org/10.1007/s00239-002-2446-6DOI Listing
June 2003

DNA affinity capture and protein profiling by SELDI-TOF mass spectrometry: effect of DNA methylation.

Nucleic Acids Res 2002 Jul;30(14):e69

Division of Biology, Beckman Research Institute, The City of Hope National Medical Center, 1450 East Duarte Road, Duarte, CA 91010, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC135770PMC
http://dx.doi.org/10.1093/nar/gnf068DOI Listing
July 2002

The chicken lysozyme chromatin domain contains a second, widely expressed gene.

Nucleic Acids Res 2002 Jan;30(2):463-7

Department of Biology, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC99835PMC
http://dx.doi.org/10.1093/nar/30.2.463DOI Listing
January 2002