Publications by authors named "Arpád Kiss"

4 Publications

  • Page 1 of 1

Fabrication of a Microfluidic Flame Atomic Emission Spectrometer: a Flame-on-a-Chip.

Anal Chem 2018 05 17;90(10):5995-6000. Epub 2018 Apr 17.

Department of Inorganic and Analytical Chemistry , University of Debrecen , Egyetem ter 1. , Debrecen 4032 , Hungary.

This work demonstrates for the first time the fabrication of a microfluidic flame atomic emission spectrometer (FAES), which incorporates a microburner and flame (flame-on-a-chip). An essential part of the device is a thermospray system applied for effective sample introduction, which is more easily miniaturizable and integrable than the conventional nebulization methods. The merits and limitations of the microfluidic flame atomic emission device were demonstrated and discussed. Using a commercial cigarette lighter including butane gas, the flame temperature made the analysis of the most easily excitable alkali metals possible. The calibration diagrams for Li, Na, and K showed proper linearity in the range of 5-100 mg/L. The analytical applicability of the microfluidic FAES device was tested by analyzing various real samples.
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http://dx.doi.org/10.1021/acs.analchem.8b00774DOI Listing
May 2018

A simple method for the preparation of propargylamines using molecular sieve modified with copper(II).

Org Biomol Chem 2010 Oct 25;8(20):4575-81. Epub 2010 Aug 25.

Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1521 Budapest, Hungary.

A new, heterogeneous, 4 A molecular sieve-supported copper(ii) catalyst was developed and was used successfully in the A(3) coupling of alkynes, aldehydes and amines under simple reaction conditions.
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http://dx.doi.org/10.1039/c0ob00224kDOI Listing
October 2010

Nickel/magnesium-lanthanum mixed oxide catalyst in the Kumada-coupling.

Org Biomol Chem 2010 Jan 10;8(2):331-5. Epub 2009 Nov 10.

Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1521, Budapest, Hungary.

A new, heterogeneous, magnesium-lanthanum mixed oxide solid base-supported nickel(ii) catalyst was developed. The catalyst was used successfully in the Kumada coupling of aryl halides, especially aryl bromides. The optimal reaction conditions of the coupling were determined.
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http://dx.doi.org/10.1039/b919246hDOI Listing
January 2010

Investigation of micronized titanium dioxide penetration in human skin xenografts and its effect on cellular functions of human skin-derived cells.

Exp Dermatol 2008 Aug 28;17(8):659-67. Epub 2008 Jun 28.

Department of Dermatology, University of Debrecen, Medical and Health Science Center, Debrecen, Hungary.

Titanium dioxide (TiO2) nanoparticles are ubiquitously used materials in everyday life (e.g. paints,household products and plastic goods). However, despite the wide array of common applications, their pathogenetic role was also suggested under certain conditions (e.g. pulmonary neoplasias and lung fibrosis). From a dermatological point of view, it is also of great importance that TiO2 also serves as a physical photoprotective agent in sunscreens and is widely used in various cosmetic products. However, the effect of TiO2 on human cutaneous functions is still unknown. Therefore, in the current study, we investigated the in vivo penetration of TiO2 via human skin transplanted to immunodeficient mice and,furthermore, we measured the in vitro effects of nanoparticles on various functional properties of numerous epidermal and dermal cells in culture. Hereby, using various nuclear microscopy methods, we provide the first evidence that TiO2nanoparticles in vivo do not penetrate through the intact epidermal barrier. However, we also report that TiO2, when exposed directly to cell cultures in vitro, exerts significant and cell-type dependent effects on such cellular functions as viability, proliferation, apoptosis and differentiation. Therefore, our novel findings will hopefully inspire one to systemically explore in future, clinically oriented trials whether there is indeed a risk from micronized TiO2-containing products on skin with an impaired stratum corneum barrier function.
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http://dx.doi.org/10.1111/j.1600-0625.2007.00683.xDOI Listing
August 2008
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