Aroumougame Asaithamby

Aroumougame Asaithamby

UNVERIFIED PROFILE

Are you Aroumougame Asaithamby?   Register this Author

Register author
Aroumougame Asaithamby

Aroumougame Asaithamby

Publications by authors named "Aroumougame Asaithamby"

Are you Aroumougame Asaithamby?   Register this Author

44Publications

888Reads

22Profile Views

Tumor treating fields cause replication stress and interfere with DNA replication fork maintenance: Implications for cancer therapy.

Transl Res 2020 Mar 21;217:33-46. Epub 2019 Oct 21.

Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas; Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.trsl.2019.10.003DOI Listing
March 2020

Nuclear Foci Assays in Live Cells.

Methods Mol Biol 2019 ;1984:75-85

Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-9432-8_9DOI Listing
January 2020

Isolation of time-dependent DNA damage induced by energetic carbon ions and their fragments using fluorescent nuclear track detectors.

Med Phys 2020 Jan 19;47(1):272-281. Epub 2019 Nov 19.

Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mp.13897DOI Listing
January 2020

Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling.

Adv Protein Chem Struct Biol 2019 3;115:297-324. Epub 2019 Jan 3.

Division of Molecular Radiation Biology, Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, United States. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S18761623183007
Publisher Site
http://dx.doi.org/10.1016/bs.apcsb.2018.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287PMC
December 2019

Nonhomologous End Joining Is More Important Than Proton Linear Energy Transfer in Dictating Cell Death.

Int J Radiat Oncol Biol Phys 2019 12 16;105(5):1119-1125. Epub 2019 Aug 16.

Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas; Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2019.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872929PMC
December 2019

DNA Damage Response Mediates Pressure Overload-Induced Cardiomyocyte Hypertrophy.

Circulation 2019 02;139(9):1237-1239

Department of Internal Medicine (Y.N., N.U.N.N., F.X., J.J.S., N.T.L., T.G.G., J.A.H., H.A.S.), the University of Texas Southwestern Medical Center, Dallas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.118.034822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467068PMC
February 2019

Werner Syndrome Protein and DNA Replication.

Int J Mol Sci 2018 Nov 2;19(11). Epub 2018 Nov 2.

Division of Molecular Radiation Biology, Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

View Article

Download full-text PDF

Source
http://www.mdpi.com/1422-0067/19/11/3442
Publisher Site
http://dx.doi.org/10.3390/ijms19113442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274846PMC
November 2018

Repurposing DNA repair factors to eradicate tumor cells upon radiotherapy.

Transl Cancer Res 2017 Jul;6(Suppl 5):S822-S839

Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/tcr.2017.05.22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319958PMC
July 2017

Ionizing radiation and heart risks.

Semin Cell Dev Biol 2016 10 2;58:14-25. Epub 2016 Feb 2.

Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.semcdb.2016.01.045DOI Listing
October 2016

Tumor suppressor protein DAB2IP participates in chromosomal stability maintenance through activating spindle assembly checkpoint and stabilizing kinetochore-microtubule attachments.

Nucleic Acids Res 2016 Oct 27;44(18):8842-8854. Epub 2016 Aug 27.

Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkw746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062997PMC
October 2016

Time-Lapse Monitoring of DNA Damage Colocalized With Particle Tracks in Single Living Cells.

Int J Radiat Oncol Biol Phys 2016 09 16;96(1):221-7. Epub 2016 Apr 16.

Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas; Graduate School of Biomedical Sciences, The University of Texas, Houston, Texas. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2016.04.007DOI Listing
September 2016

Transcriptional elongation requires DNA break-induced signalling.

Nat Commun 2015 Dec 16;6:10191. Epub 2015 Dec 16.

Department of Radiation Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms10191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703865PMC
December 2015

Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart.

Nature 2015 Jul 22;523(7559):226-30. Epub 2015 Jun 22.

1] Department of Internal Medicine, Division of Cardiology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA [2] Hamon Center for Regenerative Science and Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature14582DOI Listing
July 2015

Human ventricular unloading induces cardiomyocyte proliferation.

J Am Coll Cardiol 2015 Mar 21;65(9):892-900. Epub 2015 Jan 21.

Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacc.2014.12.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488905PMC
March 2015

PTIP associates with Artemis to dictate DNA repair pathway choice.

Genes Dev 2014 Dec;28(24):2693-8

Department of Experimental Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.252478.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265673PMC
December 2014

Nonenzymatic role for WRN in preserving nascent DNA strands after replication stress.

Cell Rep 2014 Nov 6;9(4):1387-401. Epub 2014 Nov 6.

Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2014.10.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782925PMC
November 2014

MOF phosphorylation by ATM regulates 53BP1-mediated double-strand break repair pathway choice.

Cell Rep 2014 Jul 19;8(1):177-89. Epub 2014 Jun 19.

Deparment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO 63108, USA; Department of Radiation Oncology, The Houston Methodist Research Institute, Houston, TX 77030, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2014.05.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300955PMC
July 2014

New insights into the roles of ATM and DNA-PKcs in the cellular response to oxidative stress.

Cancer Lett 2012 Dec 9;327(1-2):103-10. Epub 2011 Dec 9.

Department of Radiation Oncology/Division of Molecular Radiation Biology, University of Texas Southwestern Medical Center at Dallas, 75390-9187, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2011.12.004DOI Listing
December 2012

Evidence for formation of DNA repair centers and dose-response nonlinearity in human cells.

Proc Natl Acad Sci U S A 2012 Jan 19;109(2):443-8. Epub 2011 Dec 19.

Institute of Radiation Protection, German Research Center for Environmental Health (GmbH), Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1117849108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258602PMC
January 2012

Irreparable complex DNA double-strand breaks induce chromosome breakage in organotypic three-dimensional human lung epithelial cell culture.

Nucleic Acids Res 2011 Jul 18;39(13):5474-88. Epub 2011 Mar 18.

Division of Molecular Radiation Biology, Department of Radiation Oncology, University of Texas, Southwestern Medical Centre, Dallas, TX 75390, USA.

View Article

Download full-text PDF

Source
https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
Publisher Site
http://dx.doi.org/10.1093/nar/gkr149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141259PMC
July 2011

Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation.

Mutat Res 2011 Jun 30;711(1-2):87-99. Epub 2010 Nov 30.

Division of Molecular Radiation Biology, Department of Radiation Oncology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mrfmmm.2010.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318975PMC
June 2011

Unrepaired clustered DNA lesions induce chromosome breakage in human cells.

Proc Natl Acad Sci U S A 2011 May 28;108(20):8293-8. Epub 2011 Apr 28.

Division of Molecular Radiation Biology, Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1016045108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100920PMC
May 2011

Identification of a coiled coil in werner syndrome protein that facilitates multimerization and promotes exonuclease processivity.

J Biol Chem 2010 Aug 1;285(33):25699-707. Epub 2010 Jun 1.

Division of Molecular Radiation Biology, The Scripps Research Institute, La Jolla, California 92037, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M110.124941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919133PMC
August 2010

WRN participates in translesion synthesis pathway through interaction with NBS1.

Mech Ageing Dev 2010 Jun 17;131(6):436-44. Epub 2010 Jun 17.

Department of Genome Repair Dynamics, Radiation Biology Center, Kyoto University, Kyoto 606-8501, Japan.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00476374100011
Publisher Site
http://dx.doi.org/10.1016/j.mad.2010.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911442PMC
June 2010

Cellular responses to DNA double-strand breaks after low-dose gamma-irradiation.

Nucleic Acids Res 2009 Jul 28;37(12):3912-23. Epub 2009 Apr 28.

Division of Molecular Radiation Biology, Department of Radiation Oncology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkp237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709554PMC
July 2009

Repair of HZE-particle-induced DNA double-strand breaks in normal human fibroblasts.

Radiat Res 2008 Apr;169(4):437-46

Division of Molecular Radiation Biology, Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1667/RR1165.1DOI Listing
April 2008

Ku recruits XLF to DNA double-strand breaks.

EMBO Rep 2008 Jan 7;9(1):91-6. Epub 2007 Dec 7.

Division of Molecular Radiation Biology, Department of Radiation Oncology, University of Texas Southwestern Medical Center at Dallas, 5801 Forest Park Road, Dallas, TX 75390-9187, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.embor.7401137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246615PMC
January 2008

WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing.

Nat Struct Mol Biol 2006 May 23;13(5):414-22. Epub 2006 Apr 23.

Department of Molecular Biology and Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California 92037, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nsmb1088DOI Listing
May 2006

Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks.

J Biol Chem 2005 Apr 26;280(15):14709-15. Epub 2005 Jan 26.

Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9187, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M408827200DOI Listing
April 2005

MDC1 regulates DNA-PK autophosphorylation in response to DNA damage.

J Biol Chem 2004 Nov 17;279(45):46359-62. Epub 2004 Sep 17.

Department of Oncology, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.C400375200DOI Listing
November 2004

Progesterone receptor expression in medroxyprogesterone acetate-induced murine mammary carcinomas and response to endocrine treatment.

Breast Cancer Res Treat 2003 Jun;79(3):379-90

Laboratorio de Carcinogénesis Hormonal, Instituto de Biología y Medicina Experimental-CONICET, Buenos Aires, Argentina.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1023/a:1024029826248DOI Listing
June 2003