Publications by authors named "Arnon P Kater"

100Publications

Human CXCR5 PD-1 CD8 T cells in healthy individuals and patients with hematologic malignanciesvan Bruggen.

Eur J Immunol 2020 Oct 24. Epub 2020 Oct 24.

Department of Hematology, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1002/eji.202048761DOI Listing
October 2020

Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL.

Blood 2020 Sep 29. Epub 2020 Sep 29.

Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.

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http://dx.doi.org/10.1182/blood.2020007039DOI Listing
September 2020

COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus.

Leukemia 2020 09 9;34(9):2354-2363. Epub 2020 Jul 9.

Università Vita-Salute San Raffaele and IRCC Ospedale San Raffaele, Milan, Italy.

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http://dx.doi.org/10.1038/s41375-020-0959-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347048PMC
September 2020

Response in patients with -mutated relapsed/refractory chronic lymphocytic leukemia treated with fixed-duration venetoclax and rituximab.

Haematologica 2020 Jul;105(7):e382-e383

Royal Melbourne Hospital, Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.3324/haematol.2020.253849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327665PMC
July 2020

CAR-T and ibrutinib vs CLL: sequential or simultaneous?

Blood 2020 May;135(19):1611-1612

University of Pennsylvania.

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http://dx.doi.org/10.1182/blood.2020005362DOI Listing
May 2020

Functional Differences Between EBV- and CMV-Specific CD8 T cells Demonstrate Heterogeneity of T cell Dysfunction in CLL.

Hemasphere 2020 Apr 13;4(2):e337. Epub 2020 Feb 13.

Amsterdam UMC, University of Amsterdam, Department of Hematology, Amsterdam Infection and Immunity Institute, Cancer Center Amsterdam.

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http://dx.doi.org/10.1097/HS9.0000000000000337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162091PMC
April 2020

The effectiveness of ibrutinib in chronic lymphocytic leukaemia: a nationwide, population-based study in the Netherlands.

Br J Haematol 2020 03 28;188(6):e109-e112. Epub 2020 Jan 28.

Department of Research and Development, Netherlands Comprehensive Cancer Organisation (IKNL), Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/bjh.16391DOI Listing
March 2020

Natural Killer Cell Hypo-responsiveness in Chronic Lymphocytic Leukemia can be Circumvented In Vitro by Adequate Activating Signaling.

Hemasphere 2019 Dec 30;3(6):e308. Epub 2019 Oct 30.

Amsterdam UMC, University of Amsterdam, Department of Experimental Immunology, Amsterdam Infection and Immunology Institute, Cancer Center Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1097/HS9.0000000000000308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924557PMC
December 2019

Rare but Serious: Ibrutinib Induced Liver Failure.

Hemasphere 2019 Dec 22;3(6):e307. Epub 2019 Oct 22.

Department of Hematology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1097/HS9.0000000000000307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924548PMC
December 2019

Survival continues to increase in chronic lymphocytic leukaemia: a population-based analysis among 20 468 patients diagnosed in the Netherlands between 1989 and 2016.

Br J Haematol 2020 May 20;189(3):574-577. Epub 2020 Jan 20.

Department of Research and Development, Netherlands Comprehensive Cancer Organisation (IKNL), Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/bjh.16397DOI Listing
May 2020

Dissection of the Effects of JAK and BTK Inhibitors on the Functionality of Healthy and Malignant Lymphocytes.

J Immunol 2019 10 11;203(8):2100-2109. Epub 2019 Sep 11.

Department of Experimental Immunology, Amsterdam Infection and Immunity Institute, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, the Netherlands;

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1900321
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http://dx.doi.org/10.4049/jimmunol.1900321DOI Listing
October 2019

Engaging Cytotoxic T and NK Cells for Immunotherapy in Chronic Lymphocytic Leukemia.

Int J Mol Sci 2019 Sep 3;20(17). Epub 2019 Sep 3.

Department of Hematology, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.

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http://dx.doi.org/10.3390/ijms20174315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747204PMC
September 2019

Ibrutinib and Venetoclax for First-Line Treatment of CLL.

N Engl J Med 2019 08;381(8):788-789

Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1056/NEJMc1908754DOI Listing
August 2019

Ibrutinib: searching for a partner drug.

Lancet Oncol 2019 01 3;20(1):3-5. Epub 2018 Dec 3.

Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/S1470-2045(18)30861-1DOI Listing
January 2019

Autoimmune cytopenias in chronic lymphocytic leukemia: a concise review and treatment recommendations.

Expert Rev Hematol 2018 08 14;11(8):613-624. Epub 2018 Jul 14.

a Department of Hematology and Lymphoma and Myeloma Center (LYMMCARE) , Academic Medical Center, University of Amsterdam , Amsterdam , The Netherlands.

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http://dx.doi.org/10.1080/17474086.2018.1489720DOI Listing
August 2018

Venetoclax-Rituximab in Chronic Lymphocytic Leukemia.

N Engl J Med 2018 05;378(22):2143-2144

Academic Medical Center, Amsterdam, the Netherlands

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http://dx.doi.org/10.1056/NEJMc1805135DOI Listing
May 2018

Venetoclax-Rituximab in Relapsed or Refractory Chronic Lymphocytic Leukemia.

N Engl J Med 2018 Mar;378(12):1107-1120

From the Peter MacCallum Cancer Centre, Royal Melbourne Hospital, and University of Melbourne, Melbourne, VIC (J.F.S.), and the John Curtin School of Medical Research, Australian National University, Canberra, ACT (J.D.) - all in Australia; the University of California School of Medicine, San Diego (T.J.K.), and Genentech, South San Francisco (E.A.P., Y.L., M. Mobasher) - both in California; University Hospital Cologne and the Center for Integrated Oncology Cologne-Bonn, Cologne, Germany (B.E.); St. James's University Hospital, Leeds (P.H.), and F. Hoffmann-La Roche, Welwyn Garden City (M.B., K.H.) - both in the United Kingdom; Segal Cancer Center, Lady Davis Institute, Jewish General Hospital, Montreal (S.A.), and the Departments of Medicine and Oncology, University of Calgary, Calgary, AB (C.O.) - all in Canada; Memorial Sloan Kettering Cancer Center, New York (J.G.); the Department of Hematology, Medical University of Lodz and Copernicus Memorial Hospital, Lodz, Poland (T.R.); Hospital Universitario 12 de Octubre, Madrid (J.D.S.); Medical University of Vienna, Department of Medicine I, Division of Hematology and Hemostaseology, Vienna (U.J.); the Department of Hematology, Centre Hospitalier Universitaire Montpellier, Montpellier, France (G.C.); the Department of Onco-Hematology, Division of Hematology, Niguarda Cancer Center, Niguarda Hospital, Milan (M. Montillo); AbbVie, North Chicago, IL (R.H.); and the Department of Hematology, Cancer Center Amsterdam, Academic Medical Center, Amsterdam (A.P.K.).

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http://dx.doi.org/10.1056/NEJMoa1713976DOI Listing
March 2018

Clinical Practice Guidelines for Diagnosis and Treatment of Chronic Lymphocytic Leukemia (CLL) in The Netherlands.

Clin Lymphoma Myeloma Leuk 2018 01 25;18(1):52-57. Epub 2017 Sep 25.

Department of Hematology, Lymphoma and Myeloma Center, Academic Medical Center, Amsterdam-Zuidoost, The Netherlands.

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http://dx.doi.org/10.1016/j.clml.2017.09.015DOI Listing
January 2018

CD40 signaling instructs chronic lymphocytic leukemia cells to attract monocytes via the CCR2 axis.

Haematologica 2017 12 29;102(12):2069-2076. Epub 2017 Sep 29.

Department of Hematology, Academic Medical Center, University of Amsterdam; the Netherlands

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http://dx.doi.org/10.3324/haematol.2016.157206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709106PMC
December 2017

Incidence and management of toxicity associated with ibrutinib and idelalisib: a practical approach.

Haematologica 2017 10 3;102(10):1629-1639. Epub 2017 Aug 3.

Division of Hematology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, the Netherlands.

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http://dx.doi.org/10.3324/haematol.2017.164103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622847PMC
October 2017

Chronic lymphocytic leukemia cells are active participants in microenvironmental cross-talk.

Haematologica 2017 09 3;102(9):1469-1476. Epub 2017 Aug 3.

Department of Hematology, Academic Medical Center, University of Amsterdam, the Netherlands

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http://dx.doi.org/10.3324/haematol.2016.142679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685246PMC
September 2017

'Trained immunity': consequences for lymphoid malignancies.

Haematologica 2016 12 10;101(12):1460-1468. Epub 2016 Nov 10.

Department of Hematology, Radboud University Medical Centre, Nijmegen

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http://dx.doi.org/10.3324/haematol.2016.149252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479617PMC
December 2016

Innate lymphoid cells are expanded and functionally altered in chronic lymphocytic leukemia.

Haematologica 2016 11 4;101(11):e461-e464. Epub 2016 Aug 4.

Department of Hematology, Academic Medical Center, Amsterdam, the Netherlands

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http://dx.doi.org/10.3324/haematol.2016.144725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394863PMC
November 2016

Sofosbuvir shows antiviral activity in a patient with chronic hepatitis E virus infection.

J Hepatol 2017 01 1;66(1):242-243. Epub 2016 Oct 1.

Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jhep.2016.09.014DOI Listing
January 2017

TP53 dysfunction in CLL: Implications for prognosis and treatment.

Best Pract Res Clin Haematol 2016 03 11;29(1):90-99. Epub 2016 Aug 11.

Department of Hematology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; LYMMCARE (Lymphoma and Myeloma Center), Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.beha.2016.08.002DOI Listing
March 2016

Suppression of Glut1 and Glucose Metabolism by Decreased Akt/mTORC1 Signaling Drives T Cell Impairment in B Cell Leukemia.

J Immunol 2016 09 10;197(6):2532-40. Epub 2016 Aug 10.

Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710; Department of Pathology, Microbiology, and Immunology, Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN 37232; Department of Cancer Biology, Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN 37232;

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http://dx.doi.org/10.4049/jimmunol.1502464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010978PMC
September 2016

Chronic lymphocytic leukemia development is accelerated in mice with deficiency of the pro-apoptotic regulator NOXA.

Haematologica 2016 09 13;101(9):e374-7. Epub 2016 Jun 13.

Department of Experimental Immunology, Academic Medical Center, The Netherlands Lymphoma and Myeloma Center Amsterdam (LYMMCARE), The Netherlands

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http://dx.doi.org/10.3324/haematol.2016.142323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5060034PMC
September 2016

PD-L1 blockade: rejuvenating T cells in CLL.

Blood 2015 Jul;126(2):126-8

ACADEMIC MEDICAL CENTER AMSTERDAM.

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http://dx.doi.org/10.1182/blood-2015-05-638338DOI Listing
July 2015

Resistance to ABT-199 induced by microenvironmental signals in chronic lymphocytic leukemia can be counteracted by CD20 antibodies or kinase inhibitors.

Haematologica 2015 Aug 8;100(8):e302-6. Epub 2015 May 8.

Department of Experimental Immunology, Academic Medical Center, University of Amsterdam Lymphoma and Myeloma Center Amsterdam, LYMMCARE, The Netherlands

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http://dx.doi.org/10.3324/haematol.2015.124560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004430PMC
August 2015

Ibrutinib and idelalisib synergistically target BCR-controlled adhesion in MCL and CLL: a rationale for combination therapy.

Blood 2015 Apr;125(14):2306-9

Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands Lymphoma and Myeloma Center Amsterdam - LYMMCARE, Amsterdam, The Netherlands.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-12-61
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http://dx.doi.org/10.1182/blood-2014-12-619163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416940PMC
April 2015

How does lenalidomide target the chronic lymphocytic leukemia microenvironment?

Blood 2014 Oct 26;124(14):2184-9. Epub 2014 Aug 26.

Department of Haemato-Oncology, Division of Cancer Studies, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1182/blood-2014-05-578286DOI Listing
October 2014

miR in CLL: more than mere markers of prognosis?

Blood 2014 Jul;124(1):2-4

ACADEMIC MEDICAL CENTER, UNIVERSITY OF AMSTERDAM.

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http://dx.doi.org/10.1182/blood-2014-05-574152DOI Listing
July 2014

Assessment of TP53 functionality in chronic lymphocytic leukaemia by different assays; an ERIC-wide approach.

Br J Haematol 2014 Nov 30;167(4):565-9. Epub 2014 Jun 30.

Department of Haematology, Academic Medical Centre, Amsterdam, The Netherlands; Laboratory of Exp. Immunology, Academic Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/bjh.13006DOI Listing
November 2014

Targeted resequencing for analysis of clonal composition of recurrent gene mutations in chronic lymphocytic leukaemia.

Br J Haematol 2013 Nov 27;163(4):496-500. Epub 2013 Aug 27.

Department of Translational Oncology, National Centre for Tumour Diseases (NCT) and German Cancer Research Centre (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1111/bjh.12539DOI Listing
November 2013

The biological rationale and clinical efficacy of inhibition of signaling kinases in chronic lymphocytic leukemia.

Leuk Res 2013 Jul 15;37(7):838-47. Epub 2013 Apr 15.

Department of Hematology, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.leukres.2013.03.011DOI Listing
July 2013

Highlights of the 7th young investigators' meeting on chronic lymphocytic leukemia.

Leuk Lymphoma 2013 Aug 29;54(8):1815-6. Epub 2013 May 29.

Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.3109/10428194.2013.796054DOI Listing
August 2013

A mutated B cell chronic lymphocytic leukemia subset that recognizes and responds to fungi.

J Exp Med 2013 Jan 7;210(1):59-70. Epub 2013 Jan 7.

Department of Pathology, Academic Medical Center, University of Amsterdam, 1012 ZA Amsterdam, The Netherlands.

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http://dx.doi.org/10.1084/jem.20121801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549718PMC
January 2013

Donor-derived fat tissue as a source for lipofilling after allogeneic hematopoietic cell transplantation.

J Clin Oncol 2012 Jun 30;30(17):e154-5. Epub 2012 Apr 30.

Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1200/JCO.2011.39.0476DOI Listing
June 2012

Tipping the Noxa/Mcl-1 balance overcomes ABT-737 resistance in chronic lymphocytic leukemia.

Clin Cancer Res 2012 Jan 29;18(2):487-98. Epub 2011 Nov 29.

Departments of Hematology and Experimental Immunology, and Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-1440DOI Listing
January 2012

Highlights of the 5th Young Investigators' Meeting on chronic lymphocytic leukemia.

Leuk Lymphoma 2011 Jul;52(7):1391-3

Department I of Internal Medicine and Center for Integrated Oncology, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.3109/10428194.2011.578697DOI Listing
July 2011

Development and characterization of APRIL antagonistic monoclonal antibodies for treatment of B-cell lymphomas.

Blood 2011 Jun 4;117(25):6856-65. Epub 2011 May 4.

Laboratory of Experimental Oncology and Radiobiology (LEXOR), Center for Experimental Molecular Medicine, Academic Medical Center (AMC), Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2011-01-330852DOI Listing
June 2011

B-cell activating factor and v-Myc myelocytomatosis viral oncogene homolog (c-Myc) influence progression of chronic lymphocytic leukemia.

Proc Natl Acad Sci U S A 2010 Nov 18;107(44):18956-60. Epub 2010 Oct 18.

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, Moores Cancer Center, University of California at San Diego, La Jolla, CA 92093, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1013420107
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http://dx.doi.org/10.1073/pnas.1013420107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973856PMC
November 2010

Standards for the treatment of relapsed chronic lymphocytic leukemia: a case-based study.

Clin Lymphoma Myeloma Leuk 2010 Jun;10 Suppl 1:S34-41

Department of Hematology, Academic Medical Center, The Netherlands.

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http://dx.doi.org/10.3816/CLML.2010.s.005DOI Listing
June 2010

Chronic lymphocytic leukemia of Emu-TCL1 transgenic mice undergoes rapid cell turnover that can be offset by extrinsic CD257 to accelerate disease progression.

Blood 2009 Nov 15;114(20):4469-76. Epub 2009 Sep 15.

Moores Cancer Center, Department of Medicine, School of Medicine, University of California San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1182/blood-2009-06-230169DOI Listing
November 2009

c-Abl kinase inhibitors overcome CD40-mediated drug resistance in CLL: implications for therapeutic targeting of chemoresistant niches.

Blood 2008 Dec 16;112(13):5141-9. Epub 2008 Sep 16.

Department of Hematology, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2008-03-146704DOI Listing
December 2008

Poor outcomes of chronic active Epstein-Barr virus infection and hemophagocytic lymphohistiocytosis in non-Japanese adult patients.

Clin Infect Dis 2008 Jul;47(1):105-8

Departments of 1Medical Oncology and 2Pathology, Antoni van Leeuwenhoek Hospital-Netherlands Cancer Institute, 1006 BE Amsterdam, The Netherlands.

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http://dx.doi.org/10.1086/588790DOI Listing
July 2008

Cellular immune therapy for chronic lymphocytic leukemia.

Blood 2007 Oct 16;110(8):2811-8. Epub 2007 Jul 16.

Department of Hematology, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2007-01-068932DOI Listing
October 2007

Upper-airway obstruction instigated by Sweet's syndrome.

Med Sci Monit 2007 Apr;13(4):CS53-5

Department of Intensive Care Medicine Academic Medical Center (AMC), University of Amsterdam, and the Red Cross Hospital Beverwijk, Amsterdam, The Netherlands.

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April 2007

Thymosin beta4 sequesters actin in cystic fibrosis sputum and decreases sputum cohesivity in vitro.

Chest 2006 Nov;130(5):1433-40

Department of Pediatrics, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1081, USA.

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http://dx.doi.org/10.1378/chest.130.5.1433DOI Listing
November 2006

CD154 induces p73 to overcome the resistance to apoptosis of chronic lymphocytic leukemia cells lacking functional p53.

Blood 2006 Nov 1;108(10):3450-7. Epub 2006 Jun 1.

Moores Cancer Center, University of California-San Diego School of Medicine, La Jolla, CA 92093-0663, USA.

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http://dx.doi.org/10.1182/blood-2006-04-017749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895435PMC
November 2006

Inhibitors of XIAP sensitize CD40-activated chronic lymphocytic leukemia cells to CD95-mediated apoptosis.

Blood 2005 Sep 24;106(5):1742-8. Epub 2005 May 24.

Moores Cancer Center at the University of California, San Diego, School of Medicine, University of California, San Diego, CA 92093, USA.

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http://dx.doi.org/10.1182/blood-2005-02-0695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895220PMC
September 2005

Fas-ligand (CD178) and TRAIL synergistically induce apoptosis of CD40-activated chronic lymphocytic leukemia B cells.

Blood 2005 Apr 31;105(8):3193-8. Epub 2004 Aug 31.

University of California at San Diego, La Jolla, CA 92093-0663, USA.

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http://dx.doi.org/10.1182/blood-2003-10-3684DOI Listing
April 2005

Autologous cytomegalovirus-specific T cells as effector cells in immunotherapy of B cell chronic lymphocytic leukaemia.

Br J Haematol 2004 Aug;126(4):512-6

Department of Haematology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1365-2141.2004.05070.xDOI Listing
August 2004