Publications by authors named "Arnold von Eckardstein"

100Publications

Transendothelial transport of lipoproteins.

Atherosclerosis 2020 Sep 25. Epub 2020 Sep 25.

Keenan Centre for Biomedical Research, St. Michael's Hospital, Toronto, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Canada; Interdepartmental Division of Critical Care, Department of Medicine, University of Toronto, Canada; Department of Biochemistry, University of Toronto, Canada; Institute of Medical Science, University of Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2020.09.020DOI Listing
September 2020

LDL Contributes to Reverse Cholesterol Transport.

Circ Res 2020 Aug 27;127(6):793-795. Epub 2020 Aug 27.

From the Institute of Clinical Chemistry, University Hospital Zurich, Switzerland.

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http://dx.doi.org/10.1161/CIRCRESAHA.120.317721DOI Listing
August 2020

Subunit composition of the mammalian serine-palmitoyltransferase defines the spectrum of straight and methyl-branched long-chain bases.

Proc Natl Acad Sci U S A 2020 07 23;117(27):15591-15598. Epub 2020 Jun 23.

Institute of Clinical Chemistry, University Hospital Zurich, University of Zurich, Zurich-8091, Switzerland;

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http://dx.doi.org/10.1073/pnas.2002391117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355037PMC
July 2020

Apolipoprotein M and Sphingosine-1-Phosphate: A Potentially Antidiabetic Tandem Carried by HDL.

Diabetes 2020 05;69(5):859-861

Institute of Clinical Chemistry, University of Zurich and University Hospital Zurich, Zurich, Switzerland

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http://dx.doi.org/10.2337/dbi20-0005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171970PMC
May 2020

The year 2019 in Atherosclerosis.

Atherosclerosis 2020 04 19;299:67-75. Epub 2020 Mar 19.

Institute of Clinical Chemistry, University of Zurich, University Hospital of Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2020.03.018DOI Listing
April 2020

[CME-Laboratory 61: New European Consensus Recommendations on Dyslipidemia].

Praxis (Bern 1994) 2020 ;109(3):215-220

Institut für Klinische Chemie, Universitätsspital Zürich.

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http://dx.doi.org/10.1024/1661-8157/a003437DOI Listing
July 2020

Inborn errors of apolipoprotein A-I metabolism: implications for disease, research and development.

Curr Opin Lipidol 2020 04;31(2):62-70

Institute of Clinical Chemistry, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1097/MOL.0000000000000667DOI Listing
April 2020

FADS3 is a Δ14Z sphingoid base desaturase that contributes to gender differences in the human plasma sphingolipidome.

J Biol Chem 2020 02 20;295(7):1889-1897. Epub 2019 Dec 20.

Institute for Clinical Chemistry, University Hospital and University Zurich, 8091 Zürich, Switzerland

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http://dx.doi.org/10.1074/jbc.AC119.011883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029104PMC
February 2020

[Inborn errors of high-density lipoprotein metabolism].

Internist (Berl) 2019 Dec;60(12):1311-1318

Institut für Klinische Chemie, Universitätsspital Zürich und Universität Zürich, Rämistrasse 100, 8091, Zürich, Schweiz.

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http://dx.doi.org/10.1007/s00108-019-00700-3DOI Listing
December 2019

Retinal microvascular dysfunction in patients with coronary artery disease with and without heart failure: a continuum?

Eur J Heart Fail 2019 08 4;21(8):988-997. Epub 2019 Jul 4.

Department of Cardiology, University Hospital Zurich, University Heart Center, Zurich, Switzerland.

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http://dx.doi.org/10.1002/ejhf.1537DOI Listing
August 2019

A Novel Biomarker Approach to Exploit HDL for Risk Assessment.

J Am Coll Cardiol 2019 05;73(17):2146-2149

Institute of Clinical Chemistry, University Hospital Zurich, Zurich, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07351097193392
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http://dx.doi.org/10.1016/j.jacc.2019.02.040DOI Listing
May 2019

Iron in Coronary Heart Disease-J-Shaped Associations and Ambivalent Relationships.

Clin Chem 2019 07 30;65(7):821-823. Epub 2019 Apr 30.

Institute of Clinical Chemistry, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1373/clinchem.2019.303420DOI Listing
July 2019

Inflammation during acute coronary syndromes - Risk of cardiovascular events and bleeding.

Int J Cardiol 2019 07 27;287:13-18. Epub 2019 Mar 27.

Department of Cardiology, University Heart Center, University Hospital Zurich and University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.ijcard.2019.03.049DOI Listing
July 2019

A Novel Variant (Asn177Asp) in SPTLC2 Causing Hereditary Sensory Autonomic Neuropathy Type 1C.

Neuromolecular Med 2019 06 6;21(2):182-191. Epub 2019 Apr 6.

Institute for Clinical Chemistry, University Hospital Zurich, University of Zurich, Wagistrasse 14 Schlieren, 8952, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s12017-019-08534-wDOI Listing
June 2019

Is lipoprotein(a) a risk factor for ischemic stroke and venous thromboembolism?

Clin Res Cardiol Suppl 2019 Apr;14(Suppl 1):28-32

Institute of Clinical Chemistry, University and University Hospital of Zurich, Raemistraße 100, 8091, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s11789-019-00101-8DOI Listing
April 2019

High-Sensitivity Troponin Assays in Clinical Diagnostics of Acute Coronary Syndrome.

Methods Mol Biol 2019 ;1929:645-662

Institute for Clinical Chemistry, University Hospital Zurich, Zürich, Switzerland.

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http://link.springer.com/10.1007/978-1-4939-9030-6_40
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http://dx.doi.org/10.1007/978-1-4939-9030-6_40DOI Listing
July 2019

Implications of Europe's Plan S for Atherosclerosis.

Atherosclerosis 2019 01;280:202-203

University Hospital Zurich, Institute of Clinical Chemistry, Raemistrasse 100, CH 8091 ZURICH, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.12.007DOI Listing
January 2019

Gut microbiota-dependent trimethylamine-N-oxide (TMAO) shows a U-shaped association with mortality but not with recurrent venous thromboembolism.

Thromb Res 2019 02 6;174:40-47. Epub 2018 Dec 6.

Center for Molecular Cardiology, Laboratory for Platelet Research, University of Zurich, Schlieren, Switzerland; Department of Internal Medicine, Cantonal Hospital of Baden, Baden, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2018.12.011DOI Listing
February 2019

Scavenger receptor BI promotes cytoplasmic accumulation of lipoproteins in clear-cell renal cell carcinoma.

J Lipid Res 2018 11 1;59(11):2188-2201. Epub 2018 Sep 1.

Institute of Clinical Chemistry University of Zurich and University Hospital of Zurich, Zurich, Switzerland

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http://dx.doi.org/10.1194/jlr.M083311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210910PMC
November 2018

Endocytosis of lipoproteins.

Atherosclerosis 2018 08 23;275:273-295. Epub 2018 Jun 23.

Institute for Clinical Chemistry, University and University Hospital Zurich, Zurich, Switzerland; Centre for Integrative Human Physiology, University of Zurich, Zurich, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00219150183119
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http://dx.doi.org/10.1016/j.atherosclerosis.2018.06.881DOI Listing
August 2018

CME-Labor 53/Auflösung.

Praxis (Bern 1994) 2018;107(6):341-343

1 Institut für Klinische Chemie, Universitätsspital Zürich.

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https://econtent.hogrefe.com/doi/10.1024/1661-8157/a002923
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http://dx.doi.org/10.1024/1661-8157/a002923DOI Listing
June 2018

CME-Labor 53.

Praxis (Bern 1994) 2018 Feb;107(5):253-254

1 Institut für Klinische Chemie, Universitätsspital Zürich.

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https://econtent.hogrefe.com/doi/10.1024/1661-8157/a002922
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http://dx.doi.org/10.1024/1661-8157/a002922DOI Listing
February 2018

CME-Antworten.

Praxis (Bern 1994) 2018 Feb;107(5):285

1 Klinik und Poliklinik für Innere Medizin, Universitätsspital Zürich.

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https://econtent.hogrefe.com/doi/10.1024/1661-8157/a002893
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http://dx.doi.org/10.1024/1661-8157/a002893DOI Listing
February 2018

Ongoing and new challenges of our journal.

Atherosclerosis 2018 02;269:252-253

Institute of Clinical Chemistry, University Hospital and University of Zurich, Zurich, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S00219150173142
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http://dx.doi.org/10.1016/j.atherosclerosis.2017.12.002DOI Listing
February 2018

CME: Kardiovaskuläres Screening: Sinn, Unsinn und Bedeutung der Bestimmung von Lipoprotein(a).

Praxis (Bern 1994) 2018 Feb;107(4):215-222

1 Klinik und Poliklinik für Innere Medizin, Universitätsspital Zürich.

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http://dx.doi.org/10.1024/1661-8157/a002892DOI Listing
February 2018

Alpha-1 antitrypsin deficiency: From the lung to the heart?

Atherosclerosis 2018 03 31;270:166-172. Epub 2018 Jan 31.

Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.01.042DOI Listing
March 2018

Rule-out of non-ST elevation myocardial infarction by five point of care cardiac troponin assays according to the 0 h/3 h algorithm of the European Society of Cardiology.

Clin Chem Lab Med 2018 03;56(4):649-657

Institute for Clinical Chemistry, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1515/cclm-2017-0486DOI Listing
March 2018

Reply to technical comment on: Gawinecka et al. Acute aortic dissection: pathogenesis, risk factors, diagnosis.

Swiss Med Wkly 2017 29;147:w14562. Epub 2017 Nov 29.

Institute of the Clinical Chemistry, University Hospital Zurich, Zurich, Switzerland.

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http://doi.emh.ch/smw.2017.14562
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http://dx.doi.org/10.4414/smw.2017.14562DOI Listing
May 2018

Retinal microvascular dysfunction in heart failure.

Eur Heart J 2018 01;39(1):47-56

Department of Cardiology, University Heart Center Zurich, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.

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http://dx.doi.org/10.1093/eurheartj/ehx565DOI Listing
January 2018

Biofabricating atherosclerotic plaques: In vitro engineering of a three-dimensional human fibroatheroma model.

Biomaterials 2018 Jan 28;150:49-59. Epub 2017 Sep 28.

Institute for Regenerative Medicine (IREM), University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.biomaterials.2017.09.034DOI Listing
January 2018

Clinical and scientific debates on atherosclerosis: The truth lies somewhere in the middle.

Atherosclerosis 2017 11 28;266:228. Epub 2017 Sep 28.

Institute of Clinical Chemistry, University Hospital and University of Zurich, Zurich, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S00219150173130
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http://dx.doi.org/10.1016/j.atherosclerosis.2017.09.026DOI Listing
November 2017

Evaluation of the new restandardized Abbott Architect 25-OH Vitamin D assay in vitamin D-insufficient and vitamin D-supplemented individuals.

J Clin Lab Anal 2018 May 19;32(4):e22328. Epub 2017 Sep 19.

Institute of Clinical Chemistry, University Hospital of Zurich and University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/jcla.22328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817053PMC
May 2018

Acute aortic dissection: pathogenesis, risk factors and diagnosis.

Swiss Med Wkly 2017 25;147:w14489. Epub 2017 Aug 25.

Institute of the Clinical Chemistry, University Hospital Zurich, Switzerland.

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http://doi.emh.ch/smw.2017.14489
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http://dx.doi.org/10.4414/smw.2017.14489DOI Listing
June 2018

Hypertriglyzeridämie und HDL-Mangel.

Praxis (Bern 1994) 2017 Aug;106(17):941-948

1 Institut für Klinische Chemie, Universitätsspital Zürich.

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http://dx.doi.org/10.1024/1661-8157/a002760DOI Listing
August 2017

Lipoprotein(a).

Eur Heart J 2017 05;38(20):1530-1532

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http://dx.doi.org/10.1093/eurheartj/ehx233DOI Listing
May 2017

Will you, nill you, I will treat you: the taming of lipoprotein(a).

Eur Heart J 2017 05;38(20):1570-1572

Institute of Clinical Chemistry, University and University Hospital of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1093/eurheartj/ehx232DOI Listing
May 2017

VEGF-A Regulates Cellular Localization of SR-BI as Well as Transendothelial Transport of HDL but Not LDL.

Arterioscler Thromb Vasc Biol 2017 05 30;37(5):794-803. Epub 2017 Mar 30.

From the Institute of Clinical Chemistry, University and University Hospital of Zurich, Schlieren, Switzerland (S.V., M.Y., A.P., D.P., P.Z., L.R., A.v.E.); Competence Center for Integrated Human Physiology, University of Zurich, Switzerland (S.V., M.Y., D.P., P.Z., L.R., A.v.E.); Department of Pharmacy, University of Parma, Italy (A.P.); and Scientific Center for Optical and Electron Microscopy, ETH Zurich, Switzerland (R.M., S.F.N., A.R., M.S., S.S.).

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http://dx.doi.org/10.1161/ATVBAHA.117.309284DOI Listing
May 2017

HDL cholesterol: reappraisal of its clinical relevance.

Clin Res Cardiol 2017 Sep 24;106(9):663-675. Epub 2017 Mar 24.

Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, IMED, Universitätsklinikum des Saarlandes, 66421, Homburg, Saarland, Germany.

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http://dx.doi.org/10.1007/s00392-017-1106-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565659PMC
September 2017

Procalcitonin and Midregional Proatrial Natriuretic Peptide as Biomarkers of Subclinical Cerebrovascular Damage: The Northern Manhattan Study.

Stroke 2017 03 25;48(3):604-610. Epub 2017 Jan 25.

From the Departments of Neurology (M.K., Y.M., J.D.R., J.G., M.E.) and Epidemiology (M.E.), Columbia University, New York, NY; Departments of Neurology (M.K.) and Clinical Chemistry (A.v.E., K.S.), University Hospital of Zurich, Switzerland; Department of Neurology, University of California at Davis, Sacramento (C.D.C.); and Departments of Neurology (C.W., R.S.), Public Health Sciences (R.S.), and Human Genetics (R.S.), University of Miami, FL.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.116.014945
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http://dx.doi.org/10.1161/STROKEAHA.116.014945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330783PMC
March 2017

Safety and efficacy of cardiopoietic stem cells in the treatment of post-infarction left-ventricular dysfunction - From cardioprotection to functional repair in a translational pig infarction model.

Biomaterials 2017 04 23;122:48-62. Epub 2016 Nov 23.

Institute for Regenerative Medicine (IREM), University of Zurich, Zurich, Switzerland; Wyss Translational Center Zurich, ETH and University of Zurich, Zurich, Switzerland; Disease Biophysics Group, Wyss Institute for Biologically Inspired Engineering, School of Engineering and Applied Sciences, Harvard University, Cambridge, USA.

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http://dx.doi.org/10.1016/j.biomaterials.2016.11.029DOI Listing
April 2017

Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway.

J Lipid Res 2017 01 21;58(1):60-71. Epub 2016 Nov 21.

Institute for Clinical Chemistry, University Hospital Zurich, Zurich 8091, Switzerland

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http://dx.doi.org/10.1194/jlr.M072421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234722PMC
January 2017

CME-Labor 47/Auflösung: Monoklonale Gammopathien.

Praxis (Bern 1994) 2016 Sep;105(20):1226-1229

1 Institut für Klinische Chemie, Universitätsspital Zürich.

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http://dx.doi.org/10.1024/1661-8157/a002480DOI Listing
September 2016

[Not Available].

Praxis (Bern 1994) 2016 Sep;105(19):1123-4

1 Institut für Klinische Chemie, Universitätsspital Zürich.

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http://dx.doi.org/10.1024/1661-8157/a002479DOI Listing
September 2016

ORMDL3 expression levels have no influence on the activity of serine palmitoyltransferase.

FASEB J 2016 12 19;30(12):4289-4300. Epub 2016 Sep 19.

Institute of Clinical Chemistry, University Hospital Zurich, University of Zurich, Zurich, Switzerland;

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http://dx.doi.org/10.1096/fj.201600639RDOI Listing
December 2016

[Not Available].

Praxis (Bern 1994) 2016 Jul;105(15):920-2

1 Institut für Klinische Chemie, Universitätsspital Zürich.

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http://dx.doi.org/10.1024/1661-8157/a002395DOI Listing
July 2016

Unmet Needs in LDL-C Lowering: When Statins Won't Do!

Drugs 2016 Aug;76(12):1175-90

Institute of Clinical Chemistry, University Hospital Zürich, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s40265-016-0613-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974266PMC
August 2016

Air pollution and diabetes association: Modification by type 2 diabetes genetic risk score.

Environ Int 2016 Sep 6;94:263-271. Epub 2016 Jun 6.

Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2016.04.032DOI Listing
September 2016

Elucidating the chemical structure of native 1-deoxysphingosine.

J Lipid Res 2016 07 10;57(7):1194-203. Epub 2016 May 10.

Institute of Clinical Chemistry, University and University Hospital of Zurich, CH-8091 Zurich, Switzerland

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http://dx.doi.org/10.1194/jlr.M067033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918849PMC
July 2016

HDLs in crises.

Curr Opin Lipidol 2016 06;27(3):264-73

Institute of Clinical Chemistry, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1097/MOL.0000000000000294DOI Listing
June 2016

Dysfunctional high-density lipoproteins in coronary heart disease: implications for diagnostics and therapy.

Transl Res 2016 07 24;173:30-57. Epub 2016 Feb 24.

Institute of Clinical Chemistry, University Hospital Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.trsl.2016.02.008DOI Listing
July 2016

A grateful look behind and a hopeful look ahead.

Atherosclerosis 2016 Feb 6;245:228-9. Epub 2016 Jan 6.

University and University Hospital Zurich, Institute of Clinical Chemistry, Raemistrasse 100, CH 8091 Zurich Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2015.12.043DOI Listing
February 2016

Decreased phosphatidylcholine plasmalogens--A putative novel lipid signature in patients with stable coronary artery disease and acute myocardial infarction.

Atherosclerosis 2016 Mar 6;246:130-40. Epub 2016 Jan 6.

Institute of Clinical Chemistry, University and University Hospital of Zurich, Zurich, Switzerland; Competence Center for Integrated Human Physiology, University of Zurich, Zurich, Switzerland; Competence Center for Systems Physiology and Metabolic Diseases, ETH Zurich and University of Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.01.003DOI Listing
March 2016

HSAN1 mutations in serine palmitoyltransferase reveal a close structure-function-phenotype relationship.

Hum Mol Genet 2016 Mar 17;25(5):853-65. Epub 2015 Dec 17.

Institute for Clinical Chemistry, University Hospital Zurich, Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland, Competence Center for Personalized Medicine (CC-PM), Molecular Translation and Biomedicine (MTB), and

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http://hmg.oxfordjournals.org/content/early/2016/01/11/hmg.d
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http://hmg.oxfordjournals.org/content/early/2015/12/16/hmg.d
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http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddv
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http://dx.doi.org/10.1093/hmg/ddv611DOI Listing
March 2016

Itinerary of high density lipoproteins in endothelial cells.

Biochim Biophys Acta 2016 Feb 11;1861(2):98-107. Epub 2015 Nov 11.

Institute of Clinical Chemistry, University and University Hospital of Zurich, Switzerland; Competence Center for Integrated Human Physiology, University of Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2015.11.004DOI Listing
February 2016

Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control.

Atherosclerosis 2015 Dec 24;243(2):638-44. Epub 2015 Oct 24.

Institute of Clinical Chemistry, University Hospital and University of Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2015.10.091DOI Listing
December 2015

Fenofibrate lowers atypical sphingolipids in plasma of dyslipidemic patients: A novel approach for treating diabetic neuropathy?

J Clin Lipidol 2015 Jul-Aug;9(4):568-75. Epub 2015 Apr 4.

Institute for Clinical Chemistry, University Hospital Zurich, Zurich, Switzerland; Centre for Integrative Human Physiology, University of Zurich, Zurich, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19332874150009
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http://dx.doi.org/10.1016/j.jacl.2015.03.011DOI Listing
May 2016

Iodine Supplementation Decreases Hypercholesterolemia in Iodine-Deficient, Overweight Women: A Randomized Controlled Trial.

J Nutr 2015 Sep 22;145(9):2067-75. Epub 2015 Jul 22.

Human Nutrition Laboratory, Institute of Food, Nutrition, and Health, ETH Zurich, Zurich, Switzerland; Iodine Global Network, Zurich, Switzerland.

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http://dx.doi.org/10.3945/jn.115.213439DOI Listing
September 2015