Publications by authors named "Arne Warth"

100Publications

Genome-Wide DNA Methylation Profiling in Early Stage I Lung Adenocarcinoma Reveals Predictive Aberrant Methylation in the Promoter Region of the Long Noncoding RNA PLUT: An Exploratory Study.

J Thorac Oncol 2020 08 7;15(8):1338-1350. Epub 2020 Apr 7.

Translational Lung Research Centre Heidelberg, Member of the German Centre for Lung Research (Deutsches Zentrum für Lungenforschung), Heidelberg, Germany; Translational Research Unit, Thoraxklinik at University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.jtho.2020.03.023DOI Listing
August 2020

Zerebral metastasiertes Dermatofibrosarcoma protuberans.

J Dtsch Dermatol Ges 2020 Feb;18(2):143-146

Hautklinik und Nationales Centrum für Tumorerkrankungen (NCT), Universitätsklinikum Heidelberg.

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http://dx.doi.org/10.1111/ddg.13992_gDOI Listing
February 2020

Cerebral metastases of a dermatofibrosarcoma protuberans.

J Dtsch Dermatol Ges 2020 Feb 17;18(2):143-145. Epub 2019 Dec 17.

Department of Dermatology and National Center for Tumor Diseases, University Hospital Heidelberg, Germany.

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http://dx.doi.org/10.1111/ddg.13992DOI Listing
February 2020

E3 ubiquitin ligase Smurf2: a prognostic factor in microsatellite stable colorectal cancer.

Cancer Manag Res 2019 22;11:1795-1803. Epub 2019 Feb 22.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg 69120, Germany,

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http://dx.doi.org/10.2147/CMAR.S178111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391146PMC
February 2019

Agreement of CK5/6, p40, and p63 immunoreactivity in non-small cell lung cancer.

Pathology 2019 Apr 21;51(3):240-245. Epub 2019 Feb 21.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.pathol.2018.11.009DOI Listing
April 2019

BAP1 Loss is a Useful Adjunct to Distinguish Malignant Mesothelioma Including the Adenomatoid-like Variant From Benign Adenomatoid Tumors.

Appl Immunohistochem Mol Morphol 2020 01;28(1):67-73

Institute of Pathology, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen.

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http://dx.doi.org/10.1097/PAI.0000000000000700DOI Listing
January 2020

Transbronchial Cryobiopsies for Diagnosing Interstitial Lung Disease: Real-Life Experience from a Tertiary Referral Center for Interstitial Lung Disease.

Respiration 2019;97(4):348-354. Epub 2018 Dec 14.

Center for Interstitial and Rare Lung Diseases, Thoraxklinik, University of Heidelberg, Heidelberg, Germany,

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http://dx.doi.org/10.1159/000493428DOI Listing
August 2020

Pathways regulating the expression of the immunomodulatory protein glycodelin in non‑small cell lung cancer.

Int J Oncol 2019 Feb 5;54(2):515-526. Epub 2018 Dec 5.

Translational Research Unit, Thoraxklinik at Heidelberg University Hospital, 69126 Heidelberg, Germany.

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http://dx.doi.org/10.3892/ijo.2018.4654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317686PMC
February 2019

Global DNA methylation reflects spatial heterogeneity and molecular evolution of lung adenocarcinomas.

Int J Cancer 2019 03 3;144(5):1061-1072. Epub 2018 Dec 3.

Division of Cancer Genome Research, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.31939DOI Listing
March 2019

Expression of HMB45, MelanA and SOX10 is rare in non-small cell lung cancer.

Diagn Pathol 2018 Sep 11;13(1):68. Epub 2018 Sep 11.

Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, Heidelberg, Germany.

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http://dx.doi.org/10.1186/s13000-018-0751-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134496PMC
September 2018

Molecular dissection of large cell carcinomas of the lung with null immunophenotype.

Pathology 2018 Aug 27;50(5):530-535. Epub 2018 Jun 27.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany; Translational Lung Research Center (TLRC) Heidelberg, German Center for Lung Research (DZL), Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.pathol.2018.03.005DOI Listing
August 2018

Real-World Experience with Nintedanib in Patients with Idiopathic Pulmonary Fibrosis.

Respiration 2018;95(5):301-309. Epub 2018 Feb 28.

Centre for Interstitial and Rare Lung Diseases, Department of Pneumology and Respiratory Critical Care Medicine, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1159/000485933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985741PMC
October 2018

Analysis of the proliferative activity in lung adenocarcinomas with specific driver mutations.

Pathol Res Pract 2018 Mar 2;214(3):408-416. Epub 2018 Jan 2.

Institute of Pathology, University Heidelberg, Heidelberg, Germany; Translational Lung Research Centre Heidelberg, Member of the German Centre for Lung Research, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.prp.2017.12.018DOI Listing
March 2018

Generation of a New Disease-specific Prognostic Score for Patients With Brain Metastases From Small-cell Lung Cancer Treated With Whole Brain Radiotherapy (BMS-Score) and Validation of Two Other Indices.

Clin Lung Cancer 2018 07 15;19(4):340-345. Epub 2017 Dec 15.

University Hospital Heidelberg, Department of Radiation Oncology, Heidelberg, Germany; Heidelberg Institute of Radiation Oncology (HIRO), Heidelberg, Germany; Heidelberg Ion-Beam Therapy Center (HIT), Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.cllc.2017.12.004DOI Listing
July 2018

Differential recruitment of CD44 isoforms by ErbB ligands reveals an involvement of CD44 in breast cancer.

Oncogene 2018 03 11;37(11):1472-1484. Epub 2018 Jan 11.

Karlsruhe Institute of Technology, Institute of Toxicology and Genetics, Karlsruhe, Germany.

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http://dx.doi.org/10.1038/s41388-017-0030-1DOI Listing
March 2018

FOXM1 activates AGR2 and causes progression of lung adenomas into invasive mucinous adenocarcinomas.

PLoS Genet 2017 12 21;13(12):e1007097. Epub 2017 Dec 21.

Division of Pulmonary Biology, the Perinatal Institute of Cincinnati Children's Research Foundation, Cincinnati, Ohio, United States of America.

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https://dx.plos.org/10.1371/journal.pgen.1007097
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http://dx.doi.org/10.1371/journal.pgen.1007097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755924PMC
December 2017

C-reactive protein-albumin ratio is an independent prognostic predictor of tumor recurrence in stage IIIA-N2 lung adenocarcinoma patients.

Lung Cancer 2017 12 3;114:62-67. Epub 2017 Nov 3.

Department of Thoracic Surgery, Thoraxklinik, Heidelberg University, Heidelberg, Germany; Translational Lung Research Center (TLRC), Heidelberg, Member of German Center for Lung Research (DZL), Germany. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2017.11.002DOI Listing
December 2017

Functional T cells targeting tumor-associated antigens are predictive for recurrence-free survival of patients with radically operated non-small cell lung cancer.

Oncoimmunology 2017 8;6(11):e1360458. Epub 2017 Sep 8.

Regensburg Center for Interventional Immunology and Hematology Department University Clinic and University of Regensburg, Am Biopark 9, Regensburg, BY, Germany.

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http://dx.doi.org/10.1080/2162402X.2017.1360458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674973PMC
September 2017

Spread through air spaces (STAS): a comprehensive update.

Authors:
Arne Warth

Transl Lung Cancer Res 2017 Oct;6(5):501-507

Institute of Pathology, Heidelberg University, Heidelberg, Germany.

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http://dx.doi.org/10.21037/tlcr.2017.06.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653519PMC
October 2017

Outcome and prognostic factors in single brain metastases from small-cell lung cancer.

Strahlenther Onkol 2018 02 30;194(2):98-106. Epub 2017 Oct 30.

Department of Radiation Oncology, INF 400, University Hospital Heidelberg, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00066-017-1228-4DOI Listing
February 2018

Histology of non-small cell lung cancer predicts the response to stereotactic body radiotherapy.

Radiother Oncol 2017 11 14;125(2):317-324. Epub 2017 Sep 14.

University Hospital Heidelberg, Department of Radiation Oncology, Heidelberg, Germany; National Center for Radiation Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.radonc.2017.08.029DOI Listing
November 2017

Spread through air spaces (STAS): prognostic impact of a semi-quantitative assessment.

Authors:
Arne Warth

J Thorac Dis 2017 Jul;9(7):1792-1795

Institute of Pathology, Heidelberg University, Heidelberg, Germany.

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http://dx.doi.org/10.21037/jtd.2017.06.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542947PMC
July 2017

MALDI Imaging-Guided Microproteomic Analyses of Heterogeneous Breast Tumors-A Pilot Study.

Proteomics Clin Appl 2018 01 15;12(1). Epub 2017 Sep 15.

Laboratory of Mass Spectrometry (LSM) - MolSys, Department of Chemistry, University of Liège, Liege, Belgium.

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http://dx.doi.org/10.1002/prca.201700062DOI Listing
January 2018

Qualitative Comparison Between Carrier-based and Classical Tissue Microarrays.

Appl Immunohistochem Mol Morphol 2017 Oct;25(9):e74-e79

*Department of Hematology, Oncology and Rheumatology †Institute of Pathology, University of Heidelberg, Heidelberg ‡Proteopath Trier, Trier, Germany.

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http://dx.doi.org/10.1097/PAI.0000000000000529DOI Listing
October 2017

Spatial distribution of EGFR and KRAS mutation frequencies correlates with histological growth patterns of lung adenocarcinomas.

Int J Cancer 2017 11 24;141(9):1841-1848. Epub 2017 Jul 24.

Member of the Translational Lung Research Center (TLRC) Heidelberg, German Center for Lung Research (DZL), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.30881DOI Listing
November 2017

A Prospective Study of Loose Tissue Fragments in Non-Small Cell Lung Cancer Resection Specimens: An Alternative View to "Spread Through Air Spaces".

Am J Surg Pathol 2017 Sep;41(9):1226-1230

*Department of Pathology, OLVG §Department of Pathology, Netherlands Cancer Institute Departments of ∥Epidemiology and Biostatistics ¶Pathology, VU University Medical Center, Amsterdam, The Netherlands †Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA ‡Department of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1097/PAS.0000000000000889DOI Listing
September 2017

A Novel Grading System Based on Tumor Budding and Cell Nest Size Is a Strong Predictor of Patient Outcome in Esophageal Squamous Cell Carcinoma.

Am J Surg Pathol 2017 Aug;41(8):1112-1120

*Institute of Pathology ∥Department of Surgery, Klinikum Rechts der Isar, Technical University of Munich, Munich †Institute of Pathology ‡Department of Surgery, University Hospital Heidelberg, Heidelberg §Institute of Pathology, University Hospital Erlangen, Erlangen ¶RoMED Surgical Clinic, Rosenheim #German Cancer Consortium (DKTK), Germany.

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http://dx.doi.org/10.1097/PAS.0000000000000865DOI Listing
August 2017

Targeting RET in Patients With RET-Rearranged Lung Cancers: Results From the Global, Multicenter RET Registry.

J Clin Oncol 2017 May 13;35(13):1403-1410. Epub 2017 Mar 13.

Oliver Gautschi, Kristin Zeidler, and Joachim Diebold, Lucerne Cantonal Hospital, Luzern; Patrizia Froesch, Ente Ospedaliero Cantonale, Bellinzona; Martin Früh, Kantonsspital St Gallen, St Gallen; Sacha I. Rothschild, University Hospital Basel, Basel, Switzerland; Julie Milia and Julien Mazières, Hôpital Larrey; Thomas Filleron, Institut Universitaire du Cancer, Claudius Regaud, Toulouse; Benjamin Besse and Jordi Remon-Masip, Institute Gustave Roussy, Villejuif; Gérard Zalcman, University Hospital Bichat, Paris; Isabelle Monnet, Centre Hospitalier Intercommunal de Creteil, Creteil; Florian Cabillic, Université de Rennes 1, Rennes, France; Juergen Wolf and Sebastian Michels, Center for Integrated Oncology, Cologne; Georg Pall, Fachkliniken Wangen, Wangen Im Allgäu; Arne Warth, Heidelberg University Hospital; Thomas Muley, Thoraxklinik at University of Heidelberg and Translational Lung Research Center, Heidelberg, Germany; David P. Carbone and Dwight Owen, Ohio State University Comprehensive Cancer Center, Columbus; Vamsidhar Velcheti, Cleveland Clinic, Pepper Pike, OH; Ross Camidge and Vignhesh Narayanan, University of Colorado, Denver; Robert C. Doebele, University of Colorado, Aurora, CO; Pasi A. Janne and Mark M. Awad, Dana-Farber Cancer Institute, Boston, MA; Daniel D. Karp, The University of Texas MD Anderson Cancer Center, Houston, TX; Heather A. Wakelee and Joel W. Neal, Stanford University, Stanford; Sai-Hong Ignatius Ou, University of California, Irvine, Orange; David R. Gandara and Jonathan W. Riess, University of California, Davis Cancer Center, Sacramento, CA; Alexander Drilon, Memorial Sloan Kettering Cancer Center, New York, NY; Nir Peled, Davidoff Cancer Center, Petach Tiqwa, Israël; Chul-Cho Byoung, Yonseï Cancer Center, Seoul, Republic of Korea; Michael Van Den Heuvel, Netherlands Cancer Institute, Amsterdam, the Netherlands; Tony S.K. Mok, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region, People's Republic of China; James C.H. Yang and Jin-Yuan Shih, National Taiwan University Hospital, Taipei, Republic of China; Sanjay Popat, Royal Marsden Hospital, London, United Kingdom; and Rafael Rosell and Niki Karachaliou, Catalan Institute of Oncology, Barcelona, Spain.

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http://dx.doi.org/10.1200/JCO.2016.70.9352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559893PMC
May 2017

cR and pR: The Residual Tumor Classification Revisited.

Authors:
Arne Warth

Pathol Oncol Res 2018 01 21;24(1):195-196. Epub 2017 Apr 21.

Institute of Pathology, Heidelberg University, INF 224, D-69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s12253-017-0221-7DOI Listing
January 2018

Pulmonary ground-glass opacity: computed tomography features, histopathology and molecular pathology.

Transl Lung Cancer Res 2017 Feb;6(1):68-75

Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China.

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http://dx.doi.org/10.21037/tlcr.2017.01.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344841PMC
February 2017

Gene signature driving invasive mucinous adenocarcinoma of the lung.

EMBO Mol Med 2017 04;9(4):462-481

Perinatal Institute, Divisions of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH, USA

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http://dx.doi.org/10.15252/emmm.201606711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376761PMC
April 2017

Breaking New Ground: The Evolving Concept of Spread through Air Spaces (STAS).

J Thorac Oncol 2017 02;12(2):176-178

Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jtho.2016.10.020DOI Listing
February 2017

SMARCA4 and SMARCA2 deficiency in non-small cell lung cancer: immunohistochemical survey of 316 consecutive specimens.

Ann Diagn Pathol 2017 Feb 20;26:47-51. Epub 2016 Oct 20.

Institute of Pathology, University Hospital of Erlangen, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.anndiagpath.2016.10.006DOI Listing
February 2017

Ki-67 expression in pulmonary tumors-reply.

Transl Lung Cancer Res 2016 Oct;5(5):552-553

Institute of Pathology, Heidelberg University, Heidelberg, Germany.

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http://dx.doi.org/10.21037/tlcr.2016.10.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099518PMC
October 2016

What is better/reliable, mitosis counting or Ki67/MIB1 staining?

Transl Lung Cancer Res 2016 Oct;5(5):543-546

Institute of Pathology, Heidelberg University, Heidelberg, Germany.

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http://dx.doi.org/10.21037/tlcr.2016.10.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099505PMC
October 2016

Glycodelin is a potential novel follow-up biomarker for malignant pleural mesothelioma.

Oncotarget 2016 11;7(44):71285-71297

Translational Research Unit, Thoraxklinik at University Hospital Heidelberg, Roentgenstraße, Heidelberg, Germany.

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http://dx.doi.org/10.18632/oncotarget.12474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342078PMC
November 2016

Radiomic Analysis using Density Threshold for FDG-PET/CT-Based N-Staging in Lung Cancer Patients.

Mol Imaging Biol 2017 04;19(2):315-322

Department of Nuclear Medicine, University Hospital Heidelberg, INF 400, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s11307-016-0996-zDOI Listing
April 2017

Reliable Entity Subtyping in Non-small Cell Lung Cancer by Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry on Formalin-fixed Paraffin-embedded Tissue Specimens.

Mol Cell Proteomics 2016 10 29;15(10):3081-3089. Epub 2016 Jul 29.

From the ‡Institute of Pathology, University Heidelberg, 69120 Heidelberg, Germany; ‡‡Institute of Pathology, Technical University Munich (TUM), 81675 Munich, Germany; §§German Cancer Consortium (DKTK); ‖‖National Center for Tumor Diseases (NCT), 69120 Heidelberg, Germany.

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http://www.mcponline.org/content/15/10/3081.full.pdf
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http://dx.doi.org/10.1074/mcp.M115.057513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054336PMC
October 2016

Endoplasmic Reticulum Stress Is a Danger Signal Promoting Innate Inflammatory Responses in Bronchial Epithelial Cells.

J Innate Immun 2016 16;8(5):464-78. Epub 2016 Jul 16.

Department of Infectious Diseases, Medical Microbiology and Hygiene, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1159/000447668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738801PMC
October 2017

Impact of Comorbidities on Mortality in Patients with Idiopathic Pulmonary Fibrosis.

PLoS One 2016 29;11(3):e0151425. Epub 2016 Mar 29.

Centre for Interstitial and Rare Lung Diseases, Pneumology and Respiratory Critical Care Medicine, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0151425PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811578PMC
September 2016

Clinical Relevance of Different Papillary Growth Patterns of Pulmonary Adenocarcinoma.

Am J Surg Pathol 2016 06;40(6):818-26

*Institute of Pathology, Heidelberg University †Translational Research Unit ‡Department of Thoracic Surgery, Thoraxklinik at Heidelberg University, Heidelberg §Institute of Pathology, Technical University Munich, Munich, Germany.

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http://dx.doi.org/10.1097/PAS.0000000000000622DOI Listing
June 2016

Outcome and prognostic factors of postoperative radiation therapy (PORT) after incomplete resection of non-small cell lung cancer (NSCLC).

Lung Cancer 2016 Jan 25;91:41-7. Epub 2015 Nov 25.

Department of Radiation Oncology, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Heidelberg Institute of Radiation Oncology, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2015.11.014DOI Listing
January 2016

A randomized phase II study of radiation induced immune boost in operable non-small cell lung cancer (RadImmune trial).

BMC Cancer 2015 Dec 19;15:988. Epub 2015 Dec 19.

Departments of Molecular and Radiation Oncology, Heidelberg University Hospital and German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1186/s12885-015-2006-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684916PMC
December 2015