Arnaud Duchon

Arnaud Duchon

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Arnaud Duchon

Arnaud Duchon

Publications by authors named "Arnaud Duchon"

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22Publications

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DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome.

Front Behav Neurosci 2016 3;10:104. Epub 2016 Jun 3.

Department of Translational Medicine and Neurogenetics, Institut de Génétique et de Biologie Moléculaire et CellulaireIllkirch, France; UMR7104, Centre National de la Recherche ScientifiqueIllkirch, France; U964, Institut National de la Santé et de la Recherche MédicaleIllkirch, France; Université de StrasbourgIllkirch, France; PHENOMIN, Institut Clinique de la Souris, Groupement d'Intérêt Économique-Centre Européen de Recherche en Biologie et en Médecine, CNRS, INSERMIllkirch-Graffenstaden, France.

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http://dx.doi.org/10.3389/fnbeh.2016.00104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891327PMC
July 2016

Dosage of the Abcg1-U2af1 region modifies locomotor and cognitive deficits observed in the Tc1 mouse model of Down syndrome.

PLoS One 2015 23;10(2):e0115302. Epub 2015 Feb 23.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, 1 rue Laurent Fries, 67404 Illkirch, France; Centre National de la Recherche Scientifique, UMR7104, Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France; Université de Strasbourg, Illkirch, France; Institut Clinique de la Souris, ICS, 1 rue Laurent Fries, 67404 Illkirch, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115302PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338106PMC
December 2015

Pharmacological correction of excitation/inhibition imbalance in Down syndrome mouse models.

Front Behav Neurosci 2015 20;9:267. Epub 2015 Oct 20.

Université Paris Diderot, Sorbonne Paris Cité, Adaptive Functional Biology, UMR Centre National de la Recherche Scientifique 8251 Paris, France ; Université Pierre-et-Marie-Curie Paris, 06 UMR S 1127, Centre National de la Recherche Scientifique UMR 7225, Institut National de la Santé et de la Recherche Médicale, U 1127, Sorbonne Universités, Institut du Cerveau et de la Moelle Epiniere Paris, France.

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http://dx.doi.org/10.3389/fnbeh.2015.00267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611057PMC
November 2015

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.

Authors:
Martin Hrabě de Angelis George Nicholson Mohammed Selloum Jacqui White Hugh Morgan Ramiro Ramirez-Solis Tania Sorg Sara Wells Helmut Fuchs Martin Fray David J Adams Niels C Adams Thure Adler Antonio Aguilar-Pimentel Dalila Ali-Hadji Gregory Amann Philippe André Sarah Atkins Aurelie Auburtin Abdel Ayadi Julien Becker Lore Becker Elodie Bedu Raffi Bekeredjian Marie-Christine Birling Andrew Blake Joanna Bottomley Mike Bowl Véronique Brault Dirk H Busch James N Bussell Julia Calzada-Wack Heather Cater Marie-France Champy Philippe Charles Claire Chevalier Francesco Chiani Gemma F Codner Roy Combe Roger Cox Emilie Dalloneau André Dierich Armida Di Fenza Brendan Doe Arnaud Duchon Oliver Eickelberg Chris T Esapa Lahcen El Fertak Tanja Feigel Irina Emelyanova Jeanne Estabel Jack Favor Ann Flenniken Alessia Gambadoro Lilian Garrett Hilary Gates Anna-Karin Gerdin George Gkoutos Simon Greenaway Lisa Glasl Patrice Goetz Isabelle Goncalves Da Cruz Alexander Götz Jochen Graw Alain Guimond Wolfgang Hans Geoff Hicks Sabine M Hölter Heinz Höfler John M Hancock Robert Hoehndorf Tertius Hough Richard Houghton Anja Hurt Boris Ivandic Hughes Jacobs Sylvie Jacquot Nora Jones Natasha A Karp Hugo A Katus Sharon Kitchen Tanja Klein-Rodewald Martin Klingenspor Thomas Klopstock Valerie Lalanne Sophie Leblanc Christoph Lengger Elise le Marchand Tonia Ludwig Aline Lux Colin McKerlie Holger Maier Jean-Louis Mandel Susan Marschall Manuel Mark David G Melvin Hamid Meziane Kateryna Micklich Christophe Mittelhauser Laurent Monassier David Moulaert Stéphanie Muller Beatrix Naton Frauke Neff Patrick M Nolan Lauryl Mj Nutter Markus Ollert Guillaume Pavlovic Natalia S Pellegata Emilie Peter Benoit Petit-Demoulière Amanda Pickard Christine Podrini Paul Potter Laurent Pouilly Oliver Puk David Richardson Stephane Rousseau Leticia Quintanilla-Fend Mohamed M Quwailid Ildiko Racz Birgit Rathkolb Fabrice Riet Janet Rossant Michel Roux Jan Rozman Ed Ryder Jennifer Salisbury Luis Santos Karl-Heinz Schäble Evelyn Schiller Anja Schrewe Holger Schulz Ralf Steinkamp Michelle Simon Michelle Stewart Claudia Stöger Tobias Stöger Minxuan Sun David Sunter Lydia Teboul Isabelle Tilly Glauco P Tocchini-Valentini Monica Tost Irina Treise Laurent Vasseur Emilie Velot Daniela Vogt-Weisenhorn Christelle Wagner Alison Walling Bruno Weber Olivia Wendling Henrik Westerberg Monja Willershäuser Eckhard Wolf Anne Wolter Joe Wood Wolfgang Wurst Ali Önder Yildirim Ramona Zeh Andreas Zimmer Annemarie Zimprich Chris Holmes Karen P Steel Yann Herault Valérie Gailus-Durner Ann-Marie Mallon Steve Dm Brown

Nat Genet 2015 Sep 27;47(9):969-978. Epub 2015 Jul 27.

MRC Harwell, Medical Research Council, Harwell, UK.

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http://dx.doi.org/10.1038/ng.3360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564951PMC
September 2015

Deletion of the App-Runx1 region in mice models human partial monosomy 21.

Dis Model Mech 2015 Jun 16;8(6):623-34. Epub 2015 Apr 16.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Department of Translational Medicine and Neurogenetics, 1 rue Laurent Fries, Illkirch 67404, France Centre National de la Recherche Scientifique, UMR7104, Illkirch 67404, France Institut National de la Santé et de la Recherche Médicale, U964, Illkirch 67404, France Université de Strasbourg, Illkirch 67404, France Institut Clinique de la Souris, PHENOMIN-ICS, CNRS, INSERM, Université de Strasbourg, 1 rue Laurent Fries, Illkirch 67404, France

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http://dx.doi.org/10.1242/dmm.017814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457029PMC
June 2015

Opposite phenotypes of muscle strength and locomotor function in mouse models of partial trisomy and monosomy 21 for the proximal Hspa13-App region.

PLoS Genet 2015 Mar 24;11(3):e1005062. Epub 2015 Mar 24.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France; Centre National de la Recherche Scientifique, UMR7104, Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France; Université de Strasbourg, Illkirch, France; Institut Clinique de la Souris, PHENOMIN, GIE CERBM, Illkirch, France.

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http://dx.doi.org/10.1371/journal.pgen.1005062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372517PMC
March 2015

Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage.

Neurobiol Dis 2014 Sep 4;69:65-75. Epub 2014 May 4.

Univ Paris Diderot, Sorbonne Paris Cité, Adaptive Functional Biology, UMR CNRS 8251, 75205 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2014.04.016DOI Listing
September 2014

Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans.

Mol Nutr Food Res 2014 Feb 14;58(2):278-88. Epub 2013 Sep 14.

Human Pharmacology and Clinical Neurosciences Research Group-Neurosciences Program, IMIM-Hospital del Mar Research Institute, Barcelona, Spain; Cardiovascular Risk and Nutrition Research Group-Inflammatory and Cardiovascular Disorders Program, IMIM-Hospital del Mar Research Institute, and CIBER of Physiopathology of Obesity and Nutrition (CIBEROBN), Barcelona, Spain; University Pompeu Fabra, CEXS-UPF, Barcelona, Spain.

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http://dx.doi.org/10.1002/mnfr.201300325DOI Listing
February 2014

DYRK1A overexpression decreases plasma lecithin:cholesterol acyltransferase activity and apolipoprotein A-I levels.

Mol Genet Metab 2013 Nov 20;110(3):371-7. Epub 2013 Jul 20.

Université Paris Diderot, Sorbonne Paris Cité, Unit of Functional and Adaptive Biology (BFA), EAC-CNRS 4413, Case 7104, 75205 Paris cedex 13, France.

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http://dx.doi.org/10.1016/j.ymgme.2013.07.014DOI Listing
November 2013

The in vivo Down syndrome genomic library in mouse.

Prog Brain Res 2012 ;197:169-97

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Translational medicine and Neurogenetics program, IGBMC, CNRS, INSERM, Université de Strasbourg, UMR7104, UMR964, Illkirch, Strasbourg, France.

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http://dx.doi.org/10.1016/B978-0-444-54299-1.00009-1DOI Listing
September 2012

The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model.

PLoS Genet 2012 May 31;8(5):e1002724. Epub 2012 May 31.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Department of Translational Medicine and Neurogenetics, CNRS, INSERM, Université de Strasbourg, UMR7104, UMR964, Illkirch, France.

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http://dx.doi.org/10.1371/journal.pgen.1002724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364940PMC
May 2012

Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling Down syndrome.

Mamm Genome 2011 Dec 28;22(11-12):674-84. Epub 2011 Sep 28.

Institut de Génétique Biologie Moléculaire et Cellulaire, Translational Medicine and Neuroscience Program, Université de Strasbourg, Illkirch, France.

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http://dx.doi.org/10.1007/s00335-011-9356-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224224PMC
December 2011

Controlled somatic and germline copy number variation in the mouse model.

Curr Genomics 2010 Sep;11(6):470-80

Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U964, CNRS UMR7104, Université de Strasbourg, Illkirch, France.

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http://dx.doi.org/10.2174/138920210793176038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018727PMC
September 2010

Inducing segmental aneuploid mosaicism in the mouse through targeted asymmetric sister chromatid event of recombination.

Genetics 2008 Sep 30;180(1):51-9. Epub 2008 Aug 30.

Université d'Orléans, UMR6218, Molecular Immunology and Embryology, Orléans Cedex, France.

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http://dx.doi.org/10.1534/genetics.108.092312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2535701PMC
September 2008

Modeling the monosomy for the telomeric part of human chromosome 21 reveals haploinsufficient genes modulating the inflammatory and airway responses.

Hum Mol Genet 2007 Sep 25;16(17):2040-52. Epub 2007 Jun 25.

Institut de Tansgenose, Molecular Immunology and Embryology, Université Orléans, Férollerie, Orléans, France.

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
Publisher Site
http://dx.doi.org/10.1093/hmg/ddm152DOI Listing
September 2007