Armin Giese

Armin Giese

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Armin Giese

Publications by authors named "Armin Giese"

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Tau-induced mitochondrial membrane perturbation is dependent upon cardiolipin.

Biochim Biophys Acta Biomembr 2020 Feb 12;1862(2):183064. Epub 2019 Sep 12.

Department of Physiology and Biochemistry, Centre for Molecular Medicine and Biobanking, University of Malta, Msida, Malta. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2019.183064DOI Listing
February 2020

The small molecule inhibitor anle145c thermodynamically traps human islet amyloid peptide in the form of non-cytotoxic oligomers.

Sci Rep 2019 Dec 13;9(1):19023. Epub 2019 Dec 13.

Membrane Biochemistry and Biophysics, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/s41598-019-54919-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911113PMC
December 2019

Cardiolipin Promotes Pore-Forming Activity of Alpha-Synuclein Oligomers in Mitochondrial Membranes.

ACS Chem Neurosci 2019 Aug 6;10(8):3815-3829. Epub 2019 Aug 6.

Department of Physiology and Biochemistry and Centre for Molecular Medicine and Biobanking , University of Malta , Msida , Malta.

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http://dx.doi.org/10.1021/acschemneuro.9b00320DOI Listing
August 2019

Different Effects of α-Synuclein Mutants on Lipid Binding and Aggregation Detected by Single Molecule Fluorescence Spectroscopy and ThT Fluorescence-Based Measurements.

ACS Chem Neurosci 2019 03 16;10(3):1649-1659. Epub 2019 Jan 16.

Center for Neuropathology and Prion Research , Ludwig-Maximilians-University , Munich 81377 , Germany.

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http://dx.doi.org/10.1021/acschemneuro.8b00579DOI Listing
March 2019

TERT promoter mutation is associated with worse prognosis in WHO grade II and III meningiomas.

J Neurooncol 2018 Sep 28;139(3):671-678. Epub 2018 May 28.

Department of Neurosurgery, Ludwig-Maximilians-University Munich, Marchioninistr. 15, 81377, Munich, Germany.

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http://dx.doi.org/10.1007/s11060-018-2912-7DOI Listing
September 2018

Photophysics of diphenyl-pyrazole compounds in solutions and α-synuclein aggregates.

Biochim Biophys Acta Gen Subj 2018 Apr 19;1862(4):800-807. Epub 2017 Dec 19.

BioMolekulare Optik and Center for Integrated Protein Science CIPSM, Ludwig-Maximilians-Universität München, Oettingenstr. 67, 80538 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2017.12.007DOI Listing
April 2018

Identification of time-to-peak on dynamic 18F-FET-PET as a prognostic marker specifically in IDH1/2 mutant diffuse astrocytoma.

Neuro Oncol 2018 01;20(2):279-288

Department of Neurosurgery, Ludwig-Maximilians-University, Munich, Germany (B.S., A.B., J.C.T.); German Cancer Consortium, partner site Munich, German Cancer Research Center, Heidelberg, Germany (B.S., A.G., A.B., M.U., M.D., P.B., U.S., J.C.T., N.L.A.); Department of Neuropathology (A.G., U.S.) and Department of Nuclear Medicine (M.U., M.D., P.B., N.L.A.), Ludwig-Maximilians-University, Munich, Germany; Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland (M.W.).

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http://dx.doi.org/10.1093/neuonc/nox153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777500PMC
January 2018

Immunoprofiling of glial tumours of the neurohypophysis suggests a common pituicytic origin of neoplastic cells.

Pituitary 2017 Apr;20(2):211-217

Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.

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http://dx.doi.org/10.1007/s11102-016-0762-xDOI Listing
April 2017

MR imaging differentiation of Fe and Fe based on relaxation and magnetic susceptibility properties.

Neuroradiology 2017 Apr 21;59(4):403-409. Epub 2017 Mar 21.

Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital Munich, Munich, Germany.

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http://dx.doi.org/10.1007/s00234-017-1813-3DOI Listing
April 2017

Re-irradiation strategies in combination with bevacizumab for recurrent malignant glioma.

J Neurooncol 2016 12 6;130(3):591-599. Epub 2016 Sep 6.

Department of Radiation Oncology, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.

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http://dx.doi.org/10.1007/s11060-016-2267-xDOI Listing
December 2016

Parkinson's disease: SNCA-, PARK2-, and LRRK2- targeting microRNAs elevated in cingulate gyrus.

Parkinsonism Relat Disord 2016 12 28;33:115-121. Epub 2016 Sep 28.

Institute of Human Genetics, Justus-Liebig-University, Schlangenzahl 14, Gießen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2016.09.028DOI Listing
December 2016

An autopsy-confirmed case of progressive supranuclear palsy with predominant postural instability.

Acta Neuropathol Commun 2016 11 14;4(1):120. Epub 2016 Nov 14.

Department of Neurology, Technische Universität München, Ismaningerstr. 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1186/s40478-016-0391-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109838PMC
November 2016

Intracellular formation of α-synuclein oligomers and the effect of heat shock protein 70 characterized by confocal single particle spectroscopy.

Biochem Biophys Res Commun 2016 08 7;477(1):76-82. Epub 2016 Jun 7.

Center for Neuropathology and Prion Research, Ludwig-Maximilians-University, Feodor-Lynen-Str. 23, 81377 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.06.023DOI Listing
August 2016

Distinct Histomorphology in Molecular Subgroups of Glioblastomas in Young Patients.

J Neuropathol Exp Neurol 2016 May 14;75(5):408-14. Epub 2016 Mar 14.

From the Center for Neuropathology (JEN, AG, US) and German Center for Neurodegenerative Diseases (MMD), Ludwig-Maximilians-University, Munich, Germany; Clinical Cooperation Unit Neuropathology (G380), German Cancer Research Center (DKFZ), Heidelberg, Germany (AKor); Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany (AKor); Department of Neuropathology, Otto-von-Guericke-University, Magdeburg, Germany (CM); and Department of Neuropathology, Charité Universitätsmedizin Berlin, Berlin, Germany (AKoc).

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http://dx.doi.org/10.1093/jnen/nlw015DOI Listing
May 2016

Generation and deposition of Aβ43 by the virtually inactive presenilin-1 L435F mutant contradicts the presenilin loss-of-function hypothesis of Alzheimer's disease.

EMBO Mol Med 2016 05 2;8(5):458-65. Epub 2016 May 2.

Biomedical Center, Metabolic Biochemistry, Ludwig-Maximilians-University Munich, Munich, Germany DZNE - German Center for Neurodegenerative Diseases, Munich, Germany

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http://dx.doi.org/10.15252/emmm.201505952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119496PMC
May 2016

Spinal neuronal cannabinoid receptors mediate urodynamic effects of systemic fatty acid amide hydrolase (FAAH) inhibition in rats.

Neurourol Urodyn 2016 Apr 18;35(4):464-70. Epub 2015 Mar 18.

Division of Oncology/Unit of Urology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.

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http://dx.doi.org/10.1002/nau.22753DOI Listing
April 2016

The Differential Diagnosis and Treatment of Atypical Parkinsonism.

Dtsch Arztebl Int 2016 Feb;113(5):61-9

Department of Neurology, Klinikum rechts der Isar, Technische Universität München and Chair for Translational Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Munich, Department of Neurology, Ludwig-Maximilians-Universität München, German Center for Neurodegenerative Diseases (DZNE), Munich, Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universität München, Center for Neuropathology and Prion Research (ZNP), Ludwig-Maximilians-Universität München, Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-Universität München.

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http://dx.doi.org/10.3238/arztebl.2016.0061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782269PMC
February 2016

Interaction of α-synuclein with biomembranes in Parkinson's disease--role of cardiolipin.

Prog Lipid Res 2016 Jan 15;61:73-82. Epub 2015 Dec 15.

Dept. of Physiology and Biochemistry, University of Malta, Msida, Malta. Electronic address:

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http://dx.doi.org/10.1016/j.plipres.2015.10.005DOI Listing
January 2016

Quantifying prion disease penetrance using large population control cohorts.

Sci Transl Med 2016 Jan;8(322):322ra9

Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA 02142, USA. Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1126/scitranslmed.aad5169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774245PMC
January 2016

Age-dependent levels of 5-methyl-, 5-hydroxymethyl-, and 5-formylcytosine in human and mouse brain tissues.

Angew Chem Int Ed Engl 2015 Oct 3;54(42):12511-4. Epub 2015 Jul 3.

Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 Munich (Germany).

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http://dx.doi.org/10.1002/anie.201502722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643189PMC
October 2015

Anle138b and related compounds are aggregation specific fluorescence markers and reveal high affinity binding to α-synuclein aggregates.

Biochim Biophys Acta 2015 Sep 29;1850(9):1884-90. Epub 2015 May 29.

BioMolekulare Optik and Center for Integrated Protein Science CIPSM, Ludwig-Maximilians-Universität München, Oettingenstr. 67, 80538 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2015.05.021DOI Listing
September 2015

Quantitative Real-Time Quaking-Induced Conversion Allows Monitoring of Disease-Modifying Therapy in the Urine of Prion-Infected Mice.

J Neuropathol Exp Neurol 2015 Sep;74(9):924-33

From the Center for Neuropathology and Prion Research, Ludwig-Maximilians University, Munich (SS, JW, GMK, AG); German Center for Neurodegenerative Diseases, Bonn (JW); and NMR-Based Structural Biology, Max Planck Institute for Biophysical Chemistry, Gottingen (SR, AL, CG), Germany.

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http://dx.doi.org/10.1097/NEN.0000000000000233DOI Listing
September 2015

In Memoriam: Hans A. Kretzschmar (1953–2014).

J Neural Transm (Vienna) 2015 Jul;122(7):934-5

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http://dx.doi.org/10.1007/s00401-014-1257-3DOI Listing
July 2015

Cysteine-sparing CADASIL mutations in NOTCH3 show proaggregatory properties in vitro.

Stroke 2015 Mar 20;46(3):786-92. Epub 2015 Jan 20.

From the Institute for Stroke and Dementia Research, Klinikum der Universität München (F.A.W., P.H., A.B.-K., R.M., C.O., M.D., C.H., M.D.), Institute for Pathology (S.M.), and Center for Neuropathology and Prion Research (A.G.), Ludwig-Maximilians-University, Munich, Germany; Department of Neurology, Klinikum Stuttgart, Stuttgart, Germany (H.B.); Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, United Kingdom (F.M., K.W.M.); Department of Neurology, Klinikum am Gesundbrunnen, SLK-Kliniken, Heilbronn, Germany (C.O.); and Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (M.D.).

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http://dx.doi.org/10.1161/STROKEAHA.114.007472DOI Listing
March 2015

Histopathology and clinical course of MOG-antibody-associated encephalomyelitis.

Ann Clin Transl Neurol 2015 Mar 14;2(3):295-301. Epub 2015 Jan 14.

Institute of Clinical Neuroimmunology, Medical Campus Grosshadern, Ludwig Maximilian University Munich, Germany.

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http://dx.doi.org/10.1002/acn3.164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369279PMC
March 2015

The phenotypic spectrum of progressive supranuclear palsy: a retrospective multicenter study of 100 definite cases.

Mov Disord 2014 Dec 5;29(14):1758-66. Epub 2014 Nov 5.

Department of Neurology, Technische Universität München, Munich, Germany; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany; Department of Neurology, Philipps Universität, Marburg, Germany.

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http://www.neurokopfzentrum.med.tum.de/pdf/respondek2014.pdf
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http://doi.wiley.com/10.1002/mds.26054
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http://dx.doi.org/10.1002/mds.26054DOI Listing
December 2014

Development and implementation of a high-throughput compound screening assay for targeting disrupted ER calcium homeostasis in Alzheimer's disease.

PLoS One 2013 15;8(11):e80645. Epub 2013 Nov 15.

Department of Translational Brain Research, DZNE - German Center for Neurodegenerative Diseases, Munich, Germany ; Center for Neuropathology and Prion Research; Ludwig Maximilian University, Munich, Germany ; Graduate School of Systemic Neurosciences, Ludwig Maximilian University, Munich, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080645PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829862PMC
August 2014

Molecular stereotactic biopsy technique improves diagnostic accuracy and enables personalized treatment strategies in glioma patients.

Acta Neurochir (Wien) 2014 Aug 3;156(8):1427-40. Epub 2014 May 3.

Center for Neuropathology and Prion Research, University of Munich Medical Center - Grosshadern, Ludwig-Maximilians-University, Marchioninistr. 15, 81377, Munich, Germany.

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http://link.springer.com/10.1007/s00701-014-2073-1
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http://dx.doi.org/10.1007/s00701-014-2073-1DOI Listing
August 2014

Diffuse leukoencephalopathy with spheroids: biopsy findings and a novel mutation.

Clin Neurol Neurosurg 2014 Jul 4;122:113-5. Epub 2014 May 4.

Department of Neurology, Ludwig-Maximilians-Universität, Munich, Germany; German Research Center for Neurodegenerative Diseases (DZNE), Ludwig-Maximilians-Universität, Munich, Germany.

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http://dx.doi.org/10.1016/j.clineuro.2014.04.022DOI Listing
July 2014

Plasminogen activator inhibitor-1 influences cerebrovascular complications and death in pneumococcal meningitis.

Acta Neuropathol 2014 Apr 19;127(4):553-64. Epub 2013 Nov 19.

Department of Neurology, Academic Medical Center, Center of Infection and Immunity Amsterdam (CINIMA), University of Amsterdam, PO Box 22660, 1100 DD, Amsterdam, The Netherlands,

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http://dx.doi.org/10.1007/s00401-013-1216-4DOI Listing
April 2014

Piperazine derivatives inhibit PrP/PrP(res) propagation in vitro and in vivo.

Biochem Biophys Res Commun 2014 Feb 3;445(1):23-9. Epub 2014 Feb 3.

Institute of Novel and Emerging Infectious Diseases at the Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.01.122DOI Listing
February 2014

Mitochondrial membrane permeabilisation by amyloid aggregates and protection by polyphenols.

Biochim Biophys Acta 2013 Nov 28;1828(11):2532-43. Epub 2013 Jun 28.

Department of Physiology and Biochemistry, University of Malta, Msida, Malta.

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http://dx.doi.org/10.1016/j.bbamem.2013.06.026DOI Listing
November 2013

Presence of phosphodiesterase type 5 in the spinal cord and its involvement in bladder outflow obstruction related bladder overactivity.

J Urol 2013 Oct 29;190(4):1430-5. Epub 2013 Mar 29.

Department of Urology, Klinikum Grosshadern, Ludwig-Maximilians-University, Munich, Germany; Walter Brendel Centre of Experimental Medicine, Ludwig-Maximilians-University, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2013.03.112DOI Listing
October 2013

Adjunctive N-acetyl-L-cysteine in treatment of murine pneumococcal meningitis.

Antimicrob Agents Chemother 2013 Oct 22;57(10):4825-30. Epub 2013 Jul 22.

Department of Neurology, Ludwig-Maximilians-University Munich, Munich, Germany.

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http://dx.doi.org/10.1128/AAC.00148-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811471PMC
October 2013

Analyses of protease resistance and aggregation state of abnormal prion protein across the spectrum of human prions.

J Biol Chem 2013 Sep 29;288(39):27972-85. Epub 2013 Jul 29.

From the Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto delle Scienze Neurologiche di Bologna, 40139 Bologna, Italy.

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http://dx.doi.org/10.1074/jbc.M113.477547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784711PMC
September 2013

Polyphenolic compounds are novel protective agents against lipid membrane damage by α-synuclein aggregates in vitro.

Biochim Biophys Acta 2012 Nov 23;1818(11):2502-10. Epub 2012 May 23.

Department of Physiology and Biochemistry, University of Malta, Msida, Malta.

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http://dx.doi.org/10.1016/j.bbamem.2012.05.019DOI Listing
November 2012

Identification of polyphenolic compounds and black tea extract as potent inhibitors of lipid membrane destabilization by Aβ₄₂ aggregates.

J Alzheimers Dis 2011 ;27(4):767-79

Department of Physiology & Biochemistry, University of Malta, Msida, Malta.

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http://dx.doi.org/10.3233/JAD-2011-111061DOI Listing
April 2012

Two different binding modes of α-synuclein to lipid vesicles depending on its aggregation state.

Biophys J 2012 Apr 3;102(7):1646-55. Epub 2012 Apr 3.

Neurologische Klinik, Klinikum Großhadern, Ludwig-Maximilians-Universität, Munich, Germany.

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http://dx.doi.org/10.1016/j.bpj.2012.01.059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318129PMC
April 2012

α-Internexin in the diagnosis of oligodendroglial tumors and association with 1p/19q status.

J Neuropathol Exp Neurol 2011 Nov;70(11):970-8

Center for Neuropathology and Prion Research, Ludwig-Maximilians-University, Munich, Germany.

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http://dx.doi.org/10.1097/NEN.0b013e3182333ef5DOI Listing
November 2011

Diphenylpyrazole-derived compounds increase survival time of mice after prion infection.

Antimicrob Agents Chemother 2011 Oct 11;55(10):4774-81. Epub 2011 Jul 11.

Institute for Novel and Emerging Infectious Diseases at the Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health Südufer 10, 17493 Greifswald-Insel Riems, Germany.

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http://aac.asm.org/lookup/doi/10.1128/AAC.00151-11
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http://dx.doi.org/10.1128/AAC.00151-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186986PMC
October 2011

From high-throughput cell culture screening to mouse model: identification of new inhibitor classes against prion disease.

ChemMedChem 2011 Oct 13;6(10):1928-37. Epub 2011 Jul 13.

Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute for Novel and Emerging Infectious Diseases, Suedufer 10, 17493 Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1002/cmdc.201100119DOI Listing
October 2011

Co-aggregate formation of CADASIL-mutant NOTCH3: a single-particle analysis.

Hum Mol Genet 2011 Aug 30;20(16):3256-65. Epub 2011 May 30.

Institute for Stroke and Dementia Research, Ludwig-Maximilians-University, 81377 Munich, Germany.

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http://dx.doi.org/10.1093/hmg/ddr237DOI Listing
August 2011

Single particle analysis of tau oligomer formation induced by metal ions and organic solvents.

Biochem Biophys Res Commun 2011 Jul 24;411(1):190-6. Epub 2011 Jun 24.

Zentrum für Neuropathologie und Prionforschung, Ludwig-Maximilians-Universität, München, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2011.06.135DOI Listing
July 2011

AMPA-receptor-mediated excitatory synaptic transmission is enhanced by iron-induced α-synuclein oligomers.

J Neurochem 2011 Jun 26;117(5):868-78. Epub 2011 Apr 26.

Center of Neuropathology and Prion Research, Ludwig Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1111/j.1471-4159.2011.07254.xDOI Listing
June 2011

Inhibition and disaggregation of α-synuclein oligomers by natural polyphenolic compounds.

FEBS Lett 2011 Apr 31;585(8):1113-20. Epub 2011 Mar 31.

Dept. of Physiology & Biochemistry, University of Malta, Msida MSD 2080, Malta.

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http://dx.doi.org/10.1016/j.febslet.2011.03.046DOI Listing
April 2011

Comprehensive neuropathologic analysis of genetic prion disease associated with the E196K mutation in PRNP reveals phenotypic heterogeneity.

J Neuropathol Exp Neurol 2011 Mar;70(3):192-200

Center for Neuropathology and Prion Research, Ludwig Maximilians University Munich, Feodor-Lynen-Str. 23, 81377 Munich, Germany.

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http://dx.doi.org/10.1097/NEN.0b013e31820cd8a4DOI Listing
March 2011

Phenotypic variability of sporadic human prion disease and its molecular basis: past, present, and future.

Acta Neuropathol 2011 Jan 24;121(1):91-112. Epub 2010 Nov 24.

Dipartimento di Scienze Neurologiche, Università di Bologna, Bologna, Italy.

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http://link.springer.com/10.1007/s00401-010-0779-6
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http://dx.doi.org/10.1007/s00401-010-0779-6DOI Listing
January 2011

Reduced spiral ganglion neuronal loss by adjunctive neurotrophin-3 in experimental pneumococcal meningitis.

J Neuroinflammation 2011 Jan 24;8(1). Epub 2011 Jan 24.

Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University Munich, Marchioninistrasse 15, 81377 Munich, Germany.

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http://dx.doi.org/10.1186/1742-2094-8-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038911PMC
January 2011

Elevated levels of methylmalonate and homocysteine in Parkinson's disease, progressive supranuclear palsy and amyotrophic lateral sclerosis.

Dement Geriatr Cogn Disord 2010 3;29(6):553-9. Epub 2010 Jul 3.

Department of Neurology, Klinikum Grosshadern, Munich, Germany.

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http://dx.doi.org/10.1159/000314841DOI Listing
December 2010

Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1.

EMBO J 2010 Oct 14;29(20):3571-89. Epub 2010 Sep 14.

DZNE-German Center for Neurodegenerative Diseases,Adolf-Butenandt-Institute, Biochemistry, Ludwig-Maximilians-University, Munich, Germany.

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http://dx.doi.org/10.1038/emboj.2010.223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964170PMC
October 2010

Divergent molecular effects of desmin mutations on protein assembly in myofibrillar myopathy.

J Neuropathol Exp Neurol 2010 Apr;69(4):415-24

Klinikum Grosshadern, Department of Neurology, Ludwig-Maximilians-University of Munich, Munich, Germany.

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http://dx.doi.org/10.1097/NEN.0b013e3181d71305DOI Listing
April 2010

Converse modulation of toxic alpha-synuclein oligomers in living cells by N'-benzylidene-benzohydrazide derivates and ferric iron.

Biochem Biophys Res Commun 2010 Jan 13;391(1):461-6. Epub 2009 Nov 13.

Center for Neuropathology and Prion Research, Ludwig-Maximilians-University, Feodor-Lynen-Str 23, 81377 Munich, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2009.11.080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812586PMC
January 2010

CADASIL mutations enhance spontaneous multimerization of NOTCH3.

Hum Mol Genet 2009 Aug 5;18(15):2761-7. Epub 2009 May 5.

Department of Neurology, Ludwig-Maximilians-University, Munich, Germany.

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http://dx.doi.org/10.1093/hmg/ddp211DOI Listing
August 2009

Design of anti- and pro-aggregation variants to assess the effects of methionine oxidation in human prion protein.

Proc Natl Acad Sci U S A 2009 May 28;106(19):7756-61. Epub 2009 Apr 28.

Max-Planck-Institut für Biochemie, Am Klopferspitz 18, D-82152 Martinsried, Germany.

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http://dx.doi.org/10.1073/pnas.0902688106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674404PMC
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Increased alpha-synuclein aggregation following limited cleavage by certain matrix metalloproteinases.

Exp Neurol 2009 Jan 31;215(1):201-8. Epub 2008 Oct 31.

Neurologische Klinik, Klinikum Grosshadern, Ludwig-Maximilians-Universität München, Germany.

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January 2009

Differential effects of prion particle size on infectivity in vivo and in vitro.

Biochem Biophys Res Commun 2008 May 5;369(3):924-8. Epub 2008 Mar 5.

Center for Neuropathology and Prion Research, Ludwig Maximilians University of Munich, Feodor-Lynen-Strasse 23, 81377 Munich, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2008.02.115DOI Listing
May 2008

Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers.

J Biol Chem 2008 Apr 7;283(16):10992-1003. Epub 2008 Feb 7.

CNS Research, Boehringer Ingelheim Pharma GmbH & Co. KG, CNS Research, Birkendorferstrasse 65, 88397 Biberach, Germany.

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http://dx.doi.org/10.1074/jbc.M709634200DOI Listing
April 2008