Arlene H Sharpe

Arlene H Sharpe

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Arlene H Sharpe

Arlene H Sharpe

Publications by authors named "Arlene H Sharpe"

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Follicular regulatory T cells control humoral and allergic immunity by restraining early B cell responses.

Nat Immunol 2019 Sep 2. Epub 2019 Sep 2.

Transplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41590-019-0472-4DOI Listing
September 2019

T Cell Activation Depends on Extracellular Alanine.

Cell Rep 2019 Sep;28(12):3011-3021.e4

Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.08.034DOI Listing
September 2019

Adverse Events Following Cancer Immunotherapy: Obstacles and Opportunities.

Trends Immunol 2019 Jun 30;40(6):511-523. Epub 2019 Apr 30.

Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14714906193007
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http://dx.doi.org/10.1016/j.it.2019.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527345PMC
June 2019

FoxP3 and Ezh2 regulate Tfr cell suppressive function and transcriptional program.

J Exp Med 2019 Mar 31;216(3):605-620. Epub 2019 Jan 31.

Transplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

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http://dx.doi.org/10.1084/jem.20181134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400538PMC
March 2019

Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes.

Nat Commun 2019 02 12;10(1):713. Epub 2019 Feb 12.

Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, 1450 Biggy St NRT 5509, Los Angeles, CA, 90033, USA.

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http://dx.doi.org/10.1038/s41467-019-08449-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372786PMC
February 2019

CD160 Stimulates CD8 T Cell Responses and Is Required for Optimal Protective Immunity to .

Immunohorizons 2018 08 27;2(7):238-250. Epub 2018 Aug 27.

Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115;

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http://dx.doi.org/10.4049/immunohorizons.1800039DOI Listing
August 2018

LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade.

Cell 2018 07 21;174(3):549-563.e19. Epub 2018 Jun 21.

Division of Newborn Medicine and Epigenetics Program, Boston Children's Hospital, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.05.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063761PMC
July 2018

Role of PD-1 during effector CD8 T cell differentiation.

Proc Natl Acad Sci U S A 2018 05 13;115(18):4749-4754. Epub 2018 Apr 13.

Emory Vaccine Center, Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322;

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http://dx.doi.org/10.1073/pnas.1718217115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939075PMC
May 2018

Role of Selenof as a Gatekeeper of Secreted Disulfide-Rich Glycoproteins.

Cell Rep 2018 05;23(5):1387-1398

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.04.009DOI Listing
May 2018

TSC2-deficient tumors have evidence of T cell exhaustion and respond to anti-PD-1/anti-CTLA-4 immunotherapy.

JCI Insight 2018 Apr 19;3(8). Epub 2018 Apr 19.

Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1172/jci.insight.98674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931128PMC
April 2018

The diverse functions of the PD1 inhibitory pathway.

Nat Rev Immunol 2018 03 13;18(3):153-167. Epub 2017 Nov 13.

Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nri.2017.108DOI Listing
March 2018

Inhibitors of the PD-1 Pathway in Tumor Therapy.

J Immunol 2018 01;200(2):375-383

Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115;

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1701044
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http://dx.doi.org/10.4049/jimmunol.1701044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924692PMC
January 2018

B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells.

J Immunol 2017 12 1;199(12):3972-3980. Epub 2017 Nov 1.

Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Boston, MA 02129;

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http://dx.doi.org/10.4049/jimmunol.1700409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716898PMC
December 2017

Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state.

Nucleic Acids Res 2017 Sep;45(16):e148

Department of Electrical Engineering and Computer Science and Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA.

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http://dx.doi.org/10.1093/nar/gkx615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766189PMC
September 2017

Introduction to checkpoint inhibitors and cancer immunotherapy.

Authors:
Arlene H Sharpe

Immunol Rev 2017 03;276(1):5-8

Department of Microbiology and Immunobiology, and Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.

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http://doi.wiley.com/10.1111/imr.12531
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http://dx.doi.org/10.1111/imr.12531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362112PMC
March 2017

Suppression by T cells leads to durable and selective inhibition of B cell effector function.

Nat Immunol 2016 Dec 3;17(12):1436-1446. Epub 2016 Oct 3.

Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ni.3578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502675PMC
December 2016

Anti-CD48 Monoclonal Antibody Attenuates Experimental Autoimmune Encephalomyelitis by Limiting the Number of Pathogenic CD4+ T Cells.

J Immunol 2016 10 31;197(8):3038-3048. Epub 2016 Aug 31.

Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115;

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http://dx.doi.org/10.4049/jimmunol.1600706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356934PMC
October 2016

Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy.

Nature 2016 09 2;537(7620):417-421. Epub 2016 Aug 2.

Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1038/nature19330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297183PMC
September 2016

Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling.

Sci Signal 2016 07 26;9(438):ra75. Epub 2016 Jul 26.

Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02115, USA. Program in Immunology, Harvard Medical School, Boston, MA 02115, USA. Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1126/scisignal.aaf0626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929992PMC
July 2016

Coinhibitory Pathways in Immunotherapy for Cancer.

Annu Rev Immunol 2016 05 25;34:539-73. Epub 2016 Feb 25.

Department of Microbiology and Immunobiology, and Evergrande Center for Immunologic Diseases, Harvard Medical School, Boston, Massachusetts 02115; email:

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http://dx.doi.org/10.1146/annurev-immunol-032414-112049DOI Listing
May 2016

T follicular regulatory cells.

Immunol Rev 2016 May;271(1):246-59

Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, USA.

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http://doi.wiley.com/10.1111/imr.12411
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http://dx.doi.org/10.1111/imr.12411DOI Listing
May 2016

Coinhibitory Pathways in the B7-CD28 Ligand-Receptor Family.

Immunity 2016 05;44(5):955-72

Department of Microbiology and Immunobiology, and Evergrande Center for Immunologic Diseases, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905708PMC
May 2016

CD4 T Cell-Derived IFN-γ Plays a Minimal Role in Control of Pulmonary Mycobacterium tuberculosis Infection and Must Be Actively Repressed by PD-1 to Prevent Lethal Disease.

PLoS Pathog 2016 05 31;12(5):e1005667. Epub 2016 May 31.

T lymphocyte Biology Unit, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

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https://dx.plos.org/10.1371/journal.ppat.1005667
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http://dx.doi.org/10.1371/journal.ppat.1005667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887085PMC
May 2016

Helicobacter pylori cag pathogenicity island's role in B7-H1 induction and immune evasion.

PLoS One 2015 25;10(3):e0121841. Epub 2015 Mar 25.

Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States Of America; Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas, United States Of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121841PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373751PMC
March 2016

Roles of CD48 in regulating immunity and tolerance.

Clin Immunol 2016 Mar 18;164:10-20. Epub 2016 Jan 18.

Department of Microbiology and Immunobiology, Evergrande Center for Immunologic Diseases, Harvard Medical School, Boston, MA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15216616163000
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http://dx.doi.org/10.1016/j.clim.2016.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860950PMC
March 2016

In vitro assay to sensitively measure T(FR) suppressive capacity and T(FH) stimulation of B cell responses.

Methods Mol Biol 2015 ;1291:151-60

Department of Microbiology and Immunobiology, Harvard Medical School, NRB, 77 Avenue Louis Pasteur, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/978-1-4939-2498-1_13DOI Listing
December 2015

Mitochondrial metabolism in T cell activation and senescence: a mini-review.

Gerontology 2015 13;61(2):131-8. Epub 2014 Nov 13.

Department of Cell Biology, Harvard Medical School, Boston, Mass., USA.

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http://dx.doi.org/10.1159/000362502DOI Listing
November 2015

The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment.

Sci Adv 2015 Nov 6;1(10):e1500845. Epub 2015 Nov 6.

Cancer Center, Georgia Regents University, Augusta, GA 30912, USA. ; Department of Pediatrics, Medical College of Georgia, Georgia Regents University, Augusta, GA 30912, USA.

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http://dx.doi.org/10.1126/sciadv.1500845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640592PMC
November 2015

CD39 Expression Identifies Terminally Exhausted CD8+ T Cells.

PLoS Pathog 2015 Oct 20;11(10):e1005177. Epub 2015 Oct 20.

Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America; Division of Hematology/Oncology, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1005177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618999PMC
October 2015

ABCB5 Identifies Immunoregulatory Dermal Cells.

Cell Rep 2015 Sep 28;12(10):1564-74. Epub 2015 Aug 28.

Department of Dermatology, Brigham and Women's Hospital, Boston, MA 02115, USA; Transplantation Research Center, Boston Children's Hospital and Brigham and Women's Hospital, Boston, MA 02115, USA; School of Medical Sciences, Edith Cowan University, Joondalup, WA 6027, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565759PMC
September 2015

Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth.

Cell 2015 Sep;162(6):1242-56

Harvard Skin Disease Research Center, Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.08.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700833PMC
September 2015

Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity.

J Exp Med 2015 Sep 14;212(10):1603-21. Epub 2015 Sep 14.

Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115 Evergrande Center for Immunological Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115

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http://jem.rupress.org/content/212/10/1603.full.pdf
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http://www.jem.org/cgi/doi/10.1084/jem.20141030
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http://dx.doi.org/10.1084/jem.20141030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577848PMC
September 2015

T follicular regulatory cells in the regulation of B cell responses.

Trends Immunol 2015 Jul 17;36(7):410-8. Epub 2015 Jun 17.

Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14714906150012
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http://dx.doi.org/10.1016/j.it.2015.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508020PMC
July 2015

Defective TFH Cell Function and Increased TFR Cells Contribute to Defective Antibody Production in Aging.

Cell Rep 2015 Jul 2;12(2):163-71. Epub 2015 Jul 2.

Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247150061
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http://dx.doi.org/10.1016/j.celrep.2015.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504745PMC
July 2015

ICOS:ICOS-ligand interaction is required for type 2 innate lymphoid cell function, homeostasis, and induction of airway hyperreactivity.

Immunity 2015 Mar 10;42(3):538-51. Epub 2015 Mar 10.

Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, Los Angeles, California 90033, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613150008
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http://dx.doi.org/10.1016/j.immuni.2015.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366271PMC
March 2015

Hepatic immune regulation by stromal cells.

Curr Opin Immunol 2015 Feb 28;32:1-6. Epub 2014 Oct 28.

Cancer Immunology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2014.10.002DOI Listing
February 2015

Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability.

Nat Immunol 2015 Feb 5;16(2):188-96. Epub 2015 Jan 5.

1] Division of Medical Sciences, Harvard Medical School, Boston, Massachusetts, USA. [2] Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ni.3077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297515PMC
February 2015

Ox40L-Ox40 pathway plays distinct roles in regulating Th2 responses but does not determine outcome of cutaneous leishmaniasis caused by Leishmania mexicana and Leishmania major.

Exp Parasitol 2015 Jan 11;148:49-55. Epub 2014 Nov 11.

Department of Microbiology, The Ohio State University, Columbus, Ohio, United States; Department of Oral Biology, The Ohio State University, Columbus, Ohio, United States; Department of Pathology, The Ohio State University, Columbus, Ohio, United States. Electronic address:

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http://dx.doi.org/10.1016/j.exppara.2014.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474147PMC
January 2015

Inducible RNAi in vivo reveals that the transcription factor BATF is required to initiate but not maintain CD8+ T-cell effector differentiation.

Proc Natl Acad Sci U S A 2015 Jan 29;112(2):512-7. Epub 2014 Dec 29.

Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02115; Broad Institute of MIT and Harvard, Cambridge, MA 02142; Division of Hematology/Oncology, Children's Hospital, Harvard Medical School, Boston, MA 02115

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http://dx.doi.org/10.1073/pnas.1413291112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299213PMC
January 2015

The coinhibitory receptor CTLA-4 controls B cell responses by modulating T follicular helper, T follicular regulatory, and T regulatory cells.

Immunity 2014 Dec 5;41(6):1026-39. Epub 2014 Dec 5.

Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, 02115, USA; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309019PMC
December 2014

Balance and imbalance in the immune system: life on the edge.

Immunity 2014 Nov 20;41(5):682-4. Epub 2014 Nov 20.

Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710093PMC
November 2014

Inclusion of CD80 in HSV targets the recombinant virus to PD-L1 on DCs and allows productive infection and robust immune responses.

PLoS One 2014 27;9(1):e87617. Epub 2014 Jan 27.

Center for Neurobiology and Vaccine Development, Ophthalmology Research, Department of Surgery, Cedars-Sinai Burns & Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087617PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903765PMC
September 2014

RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance.

J Exp Med 2014 May 21;211(5):943-59. Epub 2014 Apr 21.

Department of Medical Oncology, Dana-Farber Cancer Institute; 2 Division of Immunology and Department of Pediatrics, Boston Children's Hospital; 3 Department of Microbiology and Immunobiology and 4 Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.

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http://www.jem.org/lookup/doi/10.1084/jem.20130790
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http://dx.doi.org/10.1084/jem.20130790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010901PMC
May 2014

Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses.

Immunity 2014 Apr;40(4):569-81

Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070748PMC
April 2014

GEF-H1 controls microtubule-dependent sensing of nucleic acids for antiviral host defenses.

Nat Immunol 2014 Jan 24;15(1):63-71. Epub 2013 Nov 24.

Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School.

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http://www.nature.com/articles/ni.2766
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http://dx.doi.org/10.1038/ni.2766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066330PMC
January 2014

PD-1 dependent exhaustion of CD8+ T cells drives chronic malaria.

Cell Rep 2013 Dec 5;5(5):1204-13. Epub 2013 Dec 5.

QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, QLD 4029, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2013.11.002DOI Listing
December 2013

BRAF inhibition is associated with increased clonality in tumor-infiltrating lymphocytes.

Oncoimmunology 2013 Oct 15;2(10):e26615. Epub 2013 Oct 15.

Department of Surgical Oncology; University of Texas MD Anderson Cancer Center; Houston, TX USA ; Department of Genomic Medicine; University of Texas MD Anderson Cancer Center; Houston, TX USA.

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http://www.tandfonline.com/doi/abs/10.4161/onci.26615
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http://dx.doi.org/10.4161/onci.26615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827093PMC
October 2013

Lack of PD-L1 expression by iNKT cells improves the course of influenza A infection.

PLoS One 2013 15;8(3):e59599. Epub 2013 Mar 15.

Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0059599PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598698PMC
September 2013

The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood.

Nat Immunol 2013 Feb 16;14(2):152-61. Epub 2012 Dec 16.

Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ni.2496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788614PMC
February 2013

CD28 costimulation regulates genome-wide effects on alternative splicing.

PLoS One 2012 29;7(6):e40032. Epub 2012 Jun 29.

Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0040032PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386953PMC
November 2012

Neuronal programmed cell death-1 ligand expression regulates retinal ganglion cell number in neonatal and adult mice.

J Neuroophthalmol 2012 Sep;32(3):227-37

Department of Pathology and Laboratory Medicine, Jules Stein Eye Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1097/WNO.0b013e3182589589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839320PMC
September 2012

PD-1 protects against inflammation and myocyte damage in T cell-mediated myocarditis.

J Immunol 2012 May 9;188(10):4876-84. Epub 2012 Apr 9.

Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1200389
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http://dx.doi.org/10.4049/jimmunol.1200389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345066PMC
May 2012

Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection.

Proc Natl Acad Sci U S A 2011 Dec 12;108(52):21182-7. Epub 2011 Dec 12.

Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1118450109
Publisher Site
http://dx.doi.org/10.1073/pnas.1118450109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248546PMC
December 2011