Publications by authors named "Arjan Lankester"

98Publications

Modeling Long-Term Erythropoietic Recovery After Allogeneic Stem Cell Transplants in Pediatric Patients.

Front Pediatr 2020 30;8:584156. Epub 2020 Nov 30.

Willem Alexander Children's Hospital, Leiden University Medical Center, Leiden, Netherlands.

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November 2020

Outcome of Non-hematological Autoimmunity After Hematopoietic Cell Transplantation in Children with Primary Immunodeficiency.

J Clin Immunol 2020 Nov 3. Epub 2020 Nov 3.

Children's Haematopoietic Stem Cell Transplant Unit, Great North Children's Hospital, Newcastle upon Tyne Hospital NHS Foundation Trust, Clinical Resource Building, Floor 4, Block 2, Queen Victoria Road, Newcastle upon Tyne, NE1 4LP, UK.

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November 2020

A Comprehensive Workflow for Applying Single-Cell Clustering and Pseudotime Analysis to Flow Cytometry Data.

J Immunol 2020 Aug 26;205(3):864-871. Epub 2020 Jun 26.

Department of Biomedical Data Sciences, Leiden University Medical Center, 2333 ZC Leiden, the Netherlands; and.

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August 2020

Preclinical Development of Autologous Hematopoietic Stem Cell-Based Gene Therapy for Immune Deficiencies: A Journey from Mouse Cage to Bed Side.

Pharmaceutics 2020 Jun 13;12(6). Epub 2020 Jun 13.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333ZA Leiden, The Netherlands.

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June 2020

Parental experiences in end-of-life decision-making in allogeneic pediatric stem cell transplantation: "Have I been a good parent?"

Pediatr Blood Cancer 2020 05 5;67(5):e28229. Epub 2020 Mar 5.

Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands.

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May 2020

Plasmapheresis to eliminate immunosuppressive alemtuzumab levels in a child with disseminated adenovirus infection after allogeneic stem cell transplantation.

Bone Marrow Transplant 2020 Aug 18;55(8):1671-1673. Epub 2020 Feb 18.

Department of Pediatric Stem Cell Transplantation, Willem Alexander Children's Hospital, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.

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August 2020

Integrating gene delivery and gene-editing technologies by adenoviral vector transfer of optimized CRISPR-Cas9 components.

Gene Ther 2020 05 3;27(5):209-225. Epub 2020 Jan 3.

Department of Cell and Chemical Biology (CCB), Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.

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May 2020

Hematopoietic Stem Cell Transplantation for Primary Immunodeficiencies.

Front Pediatr 2019 30;7:445. Epub 2019 Oct 30.

Department of Pediatrics, Stem Cell Transplantation Program, Willem-Alexander Children's Hospital, Leiden University Medical Center, Leiden, Netherlands.

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October 2019

Long Term Outcome and Immune Function After Hematopoietic Stem Cell Transplantation for Primary Immunodeficiency.

Front Pediatr 2019 24;7:381. Epub 2019 Sep 24.

Stem Cell Transplantation Program, Department of Pediatrics, Willem-Alexander Children's Hospital, Leiden University Medical Center, Leiden, Netherlands.

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September 2019

Leukocyte Counts and Other Hematological Values in Twin-Twin Transfusion Syndrome and Twin Anemia-Polycythemia Sequence.

Fetal Diagn Ther 2020 1;47(2):123-128. Epub 2019 Jul 1.

Division of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands,

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November 2020

B Cell Reconstitution and Influencing Factors After Hematopoietic Stem Cell Transplantation in Children.

Front Immunol 2019 12;10:782. Epub 2019 Apr 12.

Willem-Alexander Children's Hospital, Department of Pediatrics and Laboratory for Pediatric Immunology, Leiden University Medical Center, Leiden, Netherlands.

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August 2020

Determining the extent of maternal-foetal chimerism in cord blood.

Sci Rep 2019 03 27;9(1):5247. Epub 2019 Mar 27.

Sanquin Research, Dept of Hematopoiesis, Amsterdam, The Netherlands, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

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March 2019

Dynamics of the Gut Microbiota in Children Receiving Selective or Total Gut Decontamination Treatment during Hematopoietic Stem Cell Transplantation.

Biol Blood Marrow Transplant 2019 06 5;25(6):1164-1171. Epub 2019 Feb 5.

Department of Medical Microbiology, Leiden University Medical Center, Leiden, the Netherlands; Center for Microbiome Analyses and Therapeutics, Leiden University Medical Center, Leiden, the Netherlands.

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June 2019

Late effects of pediatric hematopoietic stem cell transplantation on left ventricular function, aortic stiffness and myocardial tissue characteristics.

J Cardiovasc Magn Reson 2019 01 17;21(1). Epub 2019 Jan 17.

Department of Radiology, Leiden University Medical Center, P.O. Box 9600, postal zone C2-S, 2300 RC, Leiden, The Netherlands.

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January 2019

Immunoglobulin G Fragment Crystallizable Glycosylation After Hematopoietic Stem Cell Transplantation Is Dissimilar to Donor Profiles.

Front Immunol 2018 4;9:1238. Epub 2018 Jun 4.

Department of Pediatrics, Section Immunology, Hematology and Stem Cell Transplantation, Leiden University Medical Center, Leiden, Netherlands.

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August 2019

Risk Factors, Treatment, and Immune Dysregulation in Autoimmune Cytopenia after Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients.

Biol Blood Marrow Transplant 2018 04 19;24(4):772-778. Epub 2017 Dec 19.

Department of Pediatrics, Section Immunology, Hematology and Stem Cell Transplantation, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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April 2018

In vivo and in vitro palatability testing of a new paediatric formulation of valaciclovir.

Br J Clin Pharmacol 2017 12 20;83(12):2789-2797. Epub 2017 Sep 20.

Institute of Medical Sciences, Infection, Immunity and Inflammation Research Group; Aberdeen Fungal Group, University of Aberdeen, UK.

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December 2017

The use of intravenous pentamidine for the prophylaxis of Pneumocystis pneumonia in pediatric patients.

Pediatr Blood Cancer 2017 Aug 11;64(8). Epub 2017 Jan 11.

Department of Pediatric Immunology-Infections and Stem Cell Transplantation, Leiden University Medical Center, Leiden, The Netherlands.

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August 2017

Human Circulating and Tissue-Resident CD56(bright) Natural Killer Cell Populations.

Front Immunol 2016 30;7:262. Epub 2016 Jun 30.

Department of Pediatrics, Leiden University Medical Center , Leiden , Netherlands.

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July 2016

Hematopoietic Stem Cell Transplantation in a Patient With ICF2 Syndrome Presenting With EBV-Induced Hemophagocytic Lymphohystiocytosis.

Transplantation 2016 07;100(7):e35-6

1 Leiden University Medical Center, Leiden, The Netherlands. Currently: Medical Centre Haaglanden, The Hague. 2 Sophia Childrens Hospital, Rotterdam, The Netherlands. 3 Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. 4 Erasmus Medical Centre, Rotterdam, The Netherlands. 5 Department of Clinical Genetics, Erasmus Medical Centre, Rotterdam, The Netherlands. Currently: Tragel Zorg, Clinge, The Netherlands. 6 Sophia Childrens Hospital, Rotterdam, The Netherlands. 7 Leiden University Medical Center, Leiden, The Netherlands.

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July 2016

Preparation of Cytokine-activated NK Cells for Use in Adoptive Cell Therapy in Cancer Patients: Protocol Optimization and Therapeutic Potential.

J Immunother 2016 Feb-Mar;39(2):90-100

*Pediatric Immunology Laboratory, Department of Pediatrics Departments of ‡Medical Statistics §Immunohematology and Blood Bank, Leiden University Medical Center, Leiden, The Netherlands †IRCCS AOU San Martino-IST, Genoa, Italy.

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November 2016

Association between anti-thymocyte globulin exposure and CD4+ immune reconstitution in paediatric haemopoietic cell transplantation: a multicentre, retrospective pharmacodynamic cohort analysis.

Lancet Haematol 2015 May 21;2(5):e194-203. Epub 2015 Apr 21.

Paediatric Blood and Marrow Transplant Program, University Medical Center Utrecht, Utrecht, Netherlands; U-DANCE, Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands. Electronic address:

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May 2015

Challenges in the harmonization of immune monitoring studies and trial design for cell-based therapies in the context of hematopoietic cell transplantation for pediatric cancer patients.

Cytotherapy 2015 Dec;17(12):1667-74

Blood and Marrow Transplantation Program, Department of Pediatrics, UMC Utrecht, Utrecht, Netherlands; Laboratory of Translational Immunology, UMC Utrecht, Utrecht, Netherlands. Electronic address:

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December 2015

Reactivation of Human Herpes Virus-6 After Pediatric Stem Cell Transplantation: Risk Factors, Onset, Clinical Symptoms and Association With Severity of Acute Graft-Versus-Host Disease.

Pediatr Infect Dis J 2015 Oct;34(10):1118-27

From the *Department of Pediatrics, †Department of Medical Microbiology, ‡Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands; and §Division of Hematology/Oncology, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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October 2015

Identification of the Common Origins of Osteoclasts, Macrophages, and Dendritic Cells in Human Hematopoiesis.

Stem Cell Reports 2015 Jun 21;4(6):984-94. Epub 2015 May 21.

Division of Immunology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam 1066 CX, the Netherlands. Electronic address:

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June 2015

Role of NKG2D, DNAM-1 and natural cytotoxicity receptors in cytotoxicity toward rhabdomyosarcoma cell lines mediated by resting and IL-15-activated human natural killer cells.

Cancer Immunol Immunother 2015 May 18;64(5):573-83. Epub 2015 Feb 18.

Section Immunology, Hematology, Bone Marrow Transplantation and Autoimmune Diseases, Department of Pediatrics, Leiden University Medical Center (LUMC), PO Box 9600, 2300 RC, Leiden, The Netherlands,

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May 2015

CD56(dim)CD16⁻ NK cell phenotype can be induced by cryopreservation.

Blood 2015 Mar;125(11):1842-3

Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands.

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March 2015

Treosulfan-based conditioning regimens for allogeneic HSCT in children with acute lymphoblastic leukaemia.

Ann Hematol 2015 Feb 19;94(2):297-306. Epub 2014 Sep 19.

St. Anna Kinderspital and Children's Cancer Research Institute, Department of Paediatrics, Medical University of Vienna, Kinderspitalgasse 6, 1090, Vienna, Austria,

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February 2015

Complete suppression of the gut microbiome prevents acute graft-versus-host disease following allogeneic bone marrow transplantation.

PLoS One 2014 2;9(9):e105706. Epub 2014 Sep 2.

Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands; Biomedical Primate Research Centre, Rijswijk, The Netherlands.

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May 2015

Will post-transplantation cell therapies for pediatric patients become standard of care?

Biol Blood Marrow Transplant 2015 Mar 23;21(3):402-11. Epub 2014 Jul 23.

Departments of Pediatrics and Microbiology, Immunology and Tropical Medicine, Children's National Health System and George Washington University, Division of Pediatric Hematology-Oncology, Washington, DC.

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March 2015

Mesenchymal stromal cell therapy is associated with increased adenovirus-associated but not cytomegalovirus-associated mortality in children with severe acute graft-versus-host disease.

Stem Cells Transl Med 2014 Aug 5;3(8):899-910. Epub 2014 Jun 5.

Department of Pediatrics, Immunology Section, Hematology/Oncology and Hematopoietic Stem Cell Transplantation, and Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands; Department of Hematology/Oncology and Hematopoietic Stem Cell Transplantation, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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August 2014

Characterization of human mesenchymal stem cells from ewing sarcoma patients. Pathogenetic implications.

PLoS One 2014 3;9(2):e85814. Epub 2014 Feb 3.

Molecular Pathology Program, Institute of Biomedical Research of Salamanca-Centro de Investigación del Cáncer, Centro de Investigación del Cáncer (IBSAL-CIC), Salamanca, Spain ; Instituto de Biomedicina de Sevilla (IBiS), CSIC-Universidad de Sevilla, Department of Pathology and Biobank, Hospital Universitario Virgen del Rocío, Seville, Spain.

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December 2014

Pharmacokinetics of treosulfan in pediatric patients undergoing hematopoietic stem cell transplantation.

Ther Drug Monit 2014 Aug;36(4):465-72

*Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center; †LAP&P Consultants; and ‡Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands.

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August 2014

Early cytomegalovirus reactivation leaves a specific and dynamic imprint on the reconstituting T cell compartment long-term after hematopoietic stem cell transplantation.

Biol Blood Marrow Transplant 2014 May 23;20(5):655-61. Epub 2014 Jan 23.

Department of Pediatrics, Laboratory for Immunology, Leiden University Medical Center, Leiden, The Netherlands; Pediatric HSCT unit, Leiden University Medical Center, Leiden, The Netherlands.

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May 2014