Aristotle Voineskos

Aristotle Voineskos

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Aristotle Voineskos

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The Use of Text Messaging to Improve Clinical Engagement for Individuals With Psychosis: Systematic Review.

JMIR Ment Health 2020 Apr 2;7(4):e16993. Epub 2020 Apr 2.

Slaight Centre for Youth in Transition, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.2196/16993DOI Listing
April 2020

A comparison of compensatory and restorative cognitive interventions in early psychosis.

Schizophr Res Cogn 2020 Mar 24;19:100157. Epub 2019 Jul 24.

University of Toronto Department of Psychiatry, CAMH, 250 College St., Toronto M5T1R8, Ontario, Canada.

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http://dx.doi.org/10.1016/j.scog.2019.100157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889589PMC
March 2020

The Relationship Between White Matter Microstructure and General Cognitive Ability in Patients With Schizophrenia and Healthy Participants in the ENIGMA Consortium.

Am J Psychiatry 2020 Mar 26:appiajp201919030225. Epub 2020 Mar 26.

School of Psychology, Centre for Neuroimaging and Cognitive Genomics, National Centre for Biomedical Engineering Science and Galway Neuroscience Centre, National University of Ireland Galway, Galway (Holleran, Cannon, McDonald, Morris, Mothersill, Donohoe); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Kelly, Thompson, Jahanshad); Department of Psychiatry, University of Edinburgh, Edinburgh (Alloza, Lawrie); Department of Child and Adolescent Psychiatry, Instituto de Investigación Sanitaria Gregorio Marañón, IiSGM, Hospital General Universitario Gregorio Marañón, School of Medicine, CIBERSAM, Universidad Complutense, Madrid (Alloza, Arango, Janssen, Martinez); NORMENT, K.G. Jebsen Center for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo (Agartz); Department of Psychiatry, Ullevål University Hospital and Institute of Psychiatry, University of Oslo, Oslo (Andreassen); Laboratory of Neuropsychiatry, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Rome (Banaj, Piras, Spalletta); Mind Research Network and Department of Electrical and Computer Engineering, University of New Mexico, Albuquerque (Calhoun); Neuroscience Research Australia and School of Psychiatry, University of New South Wales, Sydney (Carr); Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin (Corvin); Olin Neuropsychiatric Research Center, Institute of Living, Hartford Hospital and Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (Glahn); Department of Psychiatry, University of Pennsylvania, Philadelphia (Gur, Roalf, Satterthwaite); Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore (Hong, Kochunov, Rowland); National Institute of Mental Health, Klecany, Czech Republic (Hoschl, Spaniel); Department of Psychiatry and Mental Health (Howells, Stein, Uhlmann) and Neuroscience Institute (Howells, Stein), University of Cape Town, Cape Town, South Africa; Highfield Unit, Warneford Hospital, Oxford, U.K. (James); Mind Research Network, Lovelace Biomedical and Environmental Research Institute, Albuquerque, N.Mex. (Liu); Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Carlton South, Australia (Pantelis, Zalesky); Department of Psychiatry and Human Behavior, School of Medicine, University of California, Irvine (Potkin); Priority Centre for Brain and Mental Health Research (Schall, Rasser) and Priority Research Centre for Stroke and Brain Injury, University of Newcastle, Newcastle, Australia (Rasser); Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston (Spalletta); Kimel Family Translational Imaging-Genetics Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto (Voineskos); Department of Biomedical Engineering and Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Australia (Zalesky); Clinical Translational Neuroscience Laboratory, Department of Psychiatry and Human Behavior, and Center for the Neurobiology of Learning and Memory, University of California Irvine, Irvine (van Erp); Department of Psychology, Georgia State University, Atlanta (Turner); and Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh (Deary).

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http://dx.doi.org/10.1176/appi.ajp.2019.19030225DOI Listing
March 2020

Can we accurately classify schizophrenia patients from healthy controls using magnetic resonance imaging and machine learning? A multi-method and multi-dataset study.

Schizophr Res 2019 12 21;214:3-10. Epub 2017 Dec 21.

Computational Brain Anatomy Laboratory, Douglas Mental Health Institute, McGill University, Montreal, Quebec, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada; Department of Psychiatry, McGill University, Montreal, Quebec, Canada; Biological and Biomedical Engineering, McGill University, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2017.11.038DOI Listing
December 2019

Microstructural abnormalities in deep and superficial white matter in youths with mild traumatic brain injury.

Neuroimage Clin 2019 19;24:102102. Epub 2019 Nov 19.

Neuroscience and Mental Health Program, Hospital for Sick Children, Toronto, Ontario, Canada; Department of Physiology, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.102102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889799PMC
November 2019

Association Study of the Complement Component C4 Gene in Tardive Dyskinesia.

Front Pharmacol 2019 26;10:1339. Epub 2019 Nov 26.

Tanenbaum Centre for Pharmacogenetics, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.3389/fphar.2019.01339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901959PMC
November 2019

White matter microstructure in women with acute and remitted anorexia nervosa: an exploratory neuroimaging study.

Brain Imaging Behav 2019 Oct 11. Epub 2019 Oct 11.

Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1007/s11682-019-00193-6DOI Listing
October 2019

An overlapping pattern of cerebral cortical thinning is associated with both positive symptoms and aggression in schizophrenia via the ENIGMA consortium.

Psychol Med 2019 Oct 16:1-12. Epub 2019 Oct 16.

Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital Aachen, RWTH Aachen University, Aachen, Germany.

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http://dx.doi.org/10.1017/S0033291719002149DOI Listing
October 2019

Neuroimaging Heterogeneity in Psychosis: Neurobiological Underpinnings and Opportunities for Prognostic and Therapeutic Innovation.

Biol Psychiatry 2019 Sep 17. Epub 2019 Sep 17.

Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada; Brain and Mental Health Program, Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1016/j.biopsych.2019.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075720PMC
September 2019

Developmentally divergent sexual dimorphism in the cortico-striatal-thalamic-cortical psychosis risk pathway.

Neuropsychopharmacology 2019 08 6;44(9):1649-1658. Epub 2019 May 6.

Kimel Family Translational Imaging Genetics Research Laboratory, The Centre for Addiction and Mental Health, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1038/s41386-019-0408-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785143PMC
August 2019

Ciftify: A framework for surface-based analysis of legacy MR acquisitions.

Neuroimage 2019 08 12;197:818-826. Epub 2019 May 12.

Kimel Family Translational Imaging-Genetics Laboratory, Campbell Family Mental Health Research Institute, Centre of Addiction and Mental Health, Toronto Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.neuroimage.2019.04.078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675413PMC
August 2019

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.

Am J Hum Genet 2019 08;105(2):334-350

Division of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA; Department of Psychiatry, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY 11030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699140PMC
August 2019

Separable and Replicable Neural Strategies During Social Brain Function in People With and Without Severe Mental Illness.

Am J Psychiatry 2019 07 4;176(7):521-530. Epub 2019 Jan 4.

Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Toronto (Hawco, Calarco, Mulsant, Viviano, Dickie, Foussias, Voineskos); the Department of Psychiatry, University of Toronto, Toronto (Hawco, Foussias, Mulsant, Voineskos); Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Md. (Buchanan, Gold); Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, N.Y. (Argyelan, DeRosse, Malhotra); Zucker School of Medicine at Hofstra/Northwell, Hempstead, N.Y. (Argyelan, DeRosse, Malhotra); the Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at the University of California, Los Angeles (Iacoboni).

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http://dx.doi.org/10.1176/appi.ajp.2018.17091020DOI Listing
July 2019

An artificial neural network model for clinical score prediction in Alzheimer disease using structural neuroimaging measures

J Psychiatry Neurosci 2019 07;44(4):246-260

From the Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ont. (Bhagwat, Chakravarty); the Cerebral Imaging Centre, Douglas Mental Health University Institute, Verdun, Que. (Bhagwat, Chakravarty); the Kimel Family Translational Imaging-Genetics Research Lab, Research Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ont. (Bhagwat, Pipitone, Voineskos); the Department of Psychiatry, University of Toronto, Toronto, Ont. (Voineskos); and the Department of Psychiatry, McGill University, Montreal, Que. (Chakravarty), Canada.

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http://dx.doi.org/10.1503/jpn.180016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606432PMC
July 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Authors:
Gail Davies Max Lam Sarah E Harris Joey W Trampush Michelle Luciano W David Hill Saskia P Hagenaars Stuart J Ritchie Riccardo E Marioni Chloe Fawns-Ritchie David C M Liewald Judith A Okely Ari V Ahola-Olli Catriona L K Barnes Lars Bertram Joshua C Bis Katherine E Burdick Andrea Christoforou Pamela DeRosse Srdjan Djurovic Thomas Espeseth Stella Giakoumaki Sudheer Giddaluru Daniel E Gustavson Caroline Hayward Edith Hofer M Arfan Ikram Robert Karlsson Emma Knowles Jari Lahti Markus Leber Shuo Li Karen A Mather Ingrid Melle Derek Morris Christopher Oldmeadow Teemu Palviainen Antony Payton Raha Pazoki Katja Petrovic Chandra A Reynolds Muralidharan Sargurupremraj Markus Scholz Jennifer A Smith Albert V Smith Natalie Terzikhan Anbupalam Thalamuthu Stella Trompet Sven J van der Lee Erin B Ware B Gwen Windham Margaret J Wright Jingyun Yang Jin Yu David Ames Najaf Amin Philippe Amouyel Ole A Andreassen Nicola J Armstrong Amelia A Assareh John R Attia Deborah Attix Dimitrios Avramopoulos David A Bennett Anne C Böhmer Patricia A Boyle Henry Brodaty Harry Campbell Tyrone D Cannon Elizabeth T Cirulli Eliza Congdon Emily Drabant Conley Janie Corley Simon R Cox Anders M Dale Abbas Dehghan Danielle Dick Dwight Dickinson Johan G Eriksson Evangelos Evangelou Jessica D Faul Ian Ford Nelson A Freimer He Gao Ina Giegling Nathan A Gillespie Scott D Gordon Rebecca F Gottesman Michael E Griswold Vilmundur Gudnason Tamara B Harris Annette M Hartmann Alex Hatzimanolis Gerardo Heiss Elizabeth G Holliday Peter K Joshi Mika Kähönen Sharon L R Kardia Ida Karlsson Luca Kleineidam David S Knopman Nicole A Kochan Bettina Konte John B Kwok Stephanie Le Hellard Teresa Lee Terho Lehtimäki Shu-Chen Li Christina M Lill Tian Liu Marisa Koini Edythe London Will T Longstreth Oscar L Lopez Anu Loukola Tobias Luck Astri J Lundervold Anders Lundquist Leo-Pekka Lyytikäinen Nicholas G Martin Grant W Montgomery Alison D Murray Anna C Need Raymond Noordam Lars Nyberg William Ollier Goran Papenberg Alison Pattie Ozren Polasek Russell A Poldrack Bruce M Psaty Simone Reppermund Steffi G Riedel-Heller Richard J Rose Jerome I Rotter Panos Roussos Suvi P Rovio Yasaman Saba Fred W Sabb Perminder S Sachdev Claudia L Satizabal Matthias Schmid Rodney J Scott Matthew A Scult Jeannette Simino P Eline Slagboom Nikolaos Smyrnis Aïcha Soumaré Nikos C Stefanis David J Stott Richard E Straub Kjetil Sundet Adele M Taylor Kent D Taylor Ioanna Tzoulaki Christophe Tzourio André Uitterlinden Veronique Vitart Aristotle N Voineskos Jaakko Kaprio Michael Wagner Holger Wagner Leonie Weinhold K Hoyan Wen Elisabeth Widen Qiong Yang Wei Zhao Hieab H H Adams Dan E Arking Robert M Bilder Panos Bitsios Eric Boerwinkle Ornit Chiba-Falek Aiden Corvin Philip L De Jager Stéphanie Debette Gary Donohoe Paul Elliott Annette L Fitzpatrick Michael Gill David C Glahn Sara Hägg Narelle K Hansell Ahmad R Hariri M Kamran Ikram J Wouter Jukema Eero Vuoksimaa Matthew C Keller William S Kremen Lenore Launer Ulman Lindenberger Aarno Palotie Nancy L Pedersen Neil Pendleton David J Porteous Katri Räikkönen Olli T Raitakari Alfredo Ramirez Ivar Reinvang Igor Rudan Dan Rujescu Reinhold Schmidt Helena Schmidt Peter W Schofield Peter R Schofield John M Starr Vidar M Steen Julian N Trollor Steven T Turner Cornelia M Van Duijn Arno Villringer Daniel R Weinberger David R Weir James F Wilson Anil Malhotra Andrew M McIntosh Catharine R Gale Sudha Seshadri Thomas H Mosley Jan Bressler Todd Lencz Ian J Deary

Nat Commun 2019 May 1;10(1):2068. Epub 2019 May 1.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1038/s41467-019-10160-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494826PMC
May 2019

The Duration of Untreated Psychosis and Frontostriatal Connectivity: Toward Understanding the Impact of Untreated Psychosis on Brain Function.

Biol Psychiatry Cogn Neurosci Neuroimaging 2019 05;4(5):417-418

Kimel Family Translational Imaging-Genetics Laboratory and Slaight Family Centre for Youth in Transition, Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, and the Department of Psychiatry and Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bpsc.2019.03.002DOI Listing
May 2019

Anticholinergic Burden and Cognition in Older Patients With Schizophrenia.

J Clin Psychiatry 2017 Nov/Dec;78(9):e1284-e1290

Centre for Addiction and Mental Health, 80 Workman Way, 6th floor, Room 6312, Toronto, ON M6J1H4.

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http://dx.doi.org/10.4088/JCP.17m11523DOI Listing
April 2019

Convergent effects of a functional C3 variant on brain atrophy, demyelination, and cognitive impairment in multiple sclerosis.

Mult Scler 2019 04 27;25(4):532-540. Epub 2018 Feb 27.

Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences and Sina Hospital, Tehran, Iran/Iranian Center of Neurological Research, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1177/1352458518760715DOI Listing
April 2019

Reward-driven decision-making impairments in schizophrenia.

Schizophr Res 2019 04 12;206:277-283. Epub 2018 Nov 12.

Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.schres.2018.11.004DOI Listing
April 2019

Brain structure, cognition, and brain age in schizophrenia, bipolar disorder, and healthy controls.

Neuropsychopharmacology 2019 04 20;44(5):898-906. Epub 2018 Dec 20.

Kimel Family Translational Imaging-Genetics Laboratory, Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://www.nature.com/articles/s41386-018-0298-z
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http://dx.doi.org/10.1038/s41386-018-0298-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461913PMC
April 2019

Polygenic Risk and Neural Substrates of Attention-Deficit/Hyperactivity Disorder Symptoms in Youths With a History of Mild Traumatic Brain Injury.

Biol Psychiatry 2019 03 12;85(5):408-416. Epub 2018 Jul 12.

Neuroscience and Mental Health Program, Hospital for Sick Children, Toronto, Ontario, Canada; Department of Physiology, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2018.06.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330150PMC
March 2019

Genetic study of neuregulin 1 and receptor tyrosine-protein kinase erbB-4 in tardive dyskinesia.

World J Biol Psychiatry 2019 01 10;20(1):91-95. Epub 2017 Apr 10.

a Neurogenetics Section, Tanenbaum Centre for Pharmacogenetics, Molecular Brain Science , Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health , Toronto , ON , Canada.

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http://dx.doi.org/10.1080/15622975.2017.1301681DOI Listing
January 2019

A longitudinal human phantom reliability study of multi-center T1-weighted, DTI, and resting state fMRI data.

Psychiatry Res Neuroimaging 2018 12 9;282:134-142. Epub 2018 Jun 9.

Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, 250 College St., Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pscychresns.2018.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482446PMC
December 2018

Digital Trajectories to Care in First-Episode Psychosis.

Psychiatr Serv 2018 12 26;69(12):1259-1263. Epub 2018 Sep 26.

Dr. Birnbaum, Mrs. Rizvi, Ms. Faber, Dr. Correll, and Dr. Kane are with the Department of Psychiatry, Zucker Hillside Hospital, Northwell Health, Glen Oaks, New York. Dr. Birnbaum, Mrs. Rizvi, and Dr. Kane are also with the Feinstein Institute for Medical Research, Manhasset, New York. Dr. Correll is also with the Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin, Berlin. Dr. Addington is with Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada. Ms. Gerber is with the Department of Behavioral Health, Peacehealth Medical Group, Eugene, Oregon. Dr. Lahti is with the Department of Psychiatry, University of Alabama at Birmingham. Dr. Loewy and Dr. Mathalon are with the Department of Psychiatry, University of California, San Francisco. Dr. Mathalon is also with the Department of Veterans Affairs San Francisco Healthcare System, San Francisco. Dr. Nelson is with the School of Pharmacy, University of Missouri-Kansas City. Dr. Voineskos is with the Department of Psychiatry, University of Toronto, and the Center for Addiction and Mental Health, Toronto, Canada. Dr. Walker is with the Department of Psychology, Emory University, Atlanta. Ms. Ward is with Henderson Behavioral Health, Lauderdale Lakes, Florida.

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http://dx.doi.org/10.1176/appi.ps.201800180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408281PMC
December 2018

Resting-State Connectivity Biomarkers of Cognitive Performance and Social Function in Individuals With Schizophrenia Spectrum Disorder and Healthy Control Subjects.

Biol Psychiatry 2018 11 13;84(9):665-674. Epub 2018 Apr 13.

Kimel Family Translational Imaging-Genetics Research Lab, Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario; Department of Psychiatry, University of Toronto, Toronto, Ontario. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2018.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177285PMC
November 2018

Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium.

Authors:
Theo G M van Erp Esther Walton Derrek P Hibar Lianne Schmaal Wenhao Jiang David C Glahn Godfrey D Pearlson Nailin Yao Masaki Fukunaga Ryota Hashimoto Naohiro Okada Hidenaga Yamamori Juan R Bustillo Vincent P Clark Ingrid Agartz Bryon A Mueller Wiepke Cahn Sonja M C de Zwarte Hilleke E Hulshoff Pol René S Kahn Roel A Ophoff Neeltje E M van Haren Ole A Andreassen Anders M Dale Nhat Trung Doan Tiril P Gurholt Cecilie B Hartberg Unn K Haukvik Kjetil N Jørgensen Trine V Lagerberg Ingrid Melle Lars T Westlye Oliver Gruber Bernd Kraemer Anja Richter David Zilles Vince D Calhoun Benedicto Crespo-Facorro Roberto Roiz-Santiañez Diana Tordesillas-Gutiérrez Carmel Loughland Vaughan J Carr Stanley Catts Vanessa L Cropley Janice M Fullerton Melissa J Green Frans A Henskens Assen Jablensky Rhoshel K Lenroot Bryan J Mowry Patricia T Michie Christos Pantelis Yann Quidé Ulrich Schall Rodney J Scott Murray J Cairns Marc Seal Paul A Tooney Paul E Rasser Gavin Cooper Cynthia Shannon Weickert Thomas W Weickert Derek W Morris Elliot Hong Peter Kochunov Lauren M Beard Raquel E Gur Ruben C Gur Theodore D Satterthwaite Daniel H Wolf Aysenil Belger Gregory G Brown Judith M Ford Fabio Macciardi Daniel H Mathalon Daniel S O'Leary Steven G Potkin Adrian Preda James Voyvodic Kelvin O Lim Sarah McEwen Fude Yang Yunlong Tan Shuping Tan Zhiren Wang Fengmei Fan Jingxu Chen Hong Xiang Shiyou Tang Hua Guo Ping Wan Dong Wei Henry J Bockholt Stefan Ehrlich Rick P F Wolthusen Margaret D King Jody M Shoemaker Scott R Sponheim Lieuwe De Haan Laura Koenders Marise W Machielsen Therese van Amelsvoort Dick J Veltman Francesca Assogna Nerisa Banaj Pietro de Rossi Mariangela Iorio Fabrizio Piras Gianfranco Spalletta Peter J McKenna Edith Pomarol-Clotet Raymond Salvador Aiden Corvin Gary Donohoe Sinead Kelly Christopher D Whelan Erin W Dickie David Rotenberg Aristotle N Voineskos Simone Ciufolini Joaquim Radua Paola Dazzan Robin Murray Tiago Reis Marques Andrew Simmons Stefan Borgwardt Laura Egloff Fabienne Harrisberger Anita Riecher-Rössler Renata Smieskova Kathryn I Alpert Lei Wang Erik G Jönsson Sanne Koops Iris E C Sommer Alessandro Bertolino Aurora Bonvino Annabella Di Giorgio Emma Neilson Andrew R Mayer Julia M Stephen Jun Soo Kwon Je-Yeon Yun Dara M Cannon Colm McDonald Irina Lebedeva Alexander S Tomyshev Tolibjohn Akhadov Vasily Kaleda Helena Fatouros-Bergman Lena Flyckt Geraldo F Busatto Pedro G P Rosa Mauricio H Serpa Marcus V Zanetti Cyril Hoschl Antonin Skoch Filip Spaniel David Tomecek Saskia P Hagenaars Andrew M McIntosh Heather C Whalley Stephen M Lawrie Christian Knöchel Viola Oertel-Knöchel Michael Stäblein Fleur M Howells Dan J Stein Henk S Temmingh Anne Uhlmann Carlos Lopez-Jaramillo Danai Dima Agnes McMahon Joshua I Faskowitz Boris A Gutman Neda Jahanshad Paul M Thompson Jessica A Turner

Biol Psychiatry 2018 11 14;84(9):644-654. Epub 2018 May 14.

Imaging Genetics and Neuroinformatics Lab, Georgia State University, Atlanta, Georgia; Mind Research Network, Albuquerque, New Mexico.

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http://dx.doi.org/10.1016/j.biopsych.2018.04.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177304PMC
November 2018

Association study of Disrupted-In-Schizophrenia-1 gene variants and tardive dyskinesia.

Neurosci Lett 2018 11 15;686:17-22. Epub 2018 Aug 15.

Neurogenetics Section, Tanenbaum Centre for Pharmacogenetics, Molecular Brain Science Department, Campbell Family Mental Health Research Institute, CAMH, Canada; Institute of Medical Science, University of Toronto, Canada; Department of Psychiatry, University of Toronto, Canada; Laboratory Medicine and Pathobiology, University of Toronto, Canada. Electronic address:

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https://www.sciencedirect.com/journal/neuroscience-letters/v
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https://academic.oup.com/ntr/article-abstract/11/4/404/11007
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https://academic.oup.com/schizophreniabulletin/article/21/2/
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https://linkinghub.elsevier.com/retrieve/pii/S03043940183053
Publisher Site
http://dx.doi.org/10.1016/j.neulet.2018.08.007DOI Listing
November 2018

Spread of activity following TMS is related to intrinsic resting connectivity to the salience network: A concurrent TMS-fMRI study.

Cortex 2018 11 30;108:160-172. Epub 2018 Jul 30.

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Temerty Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.cortex.2018.07.010DOI Listing
November 2018

Predicting Functional Outcomes in Early-Stage Mental Illness: Prognostic Precision Medicine Realized?

JAMA Psychiatry 2018 11;75(11):1105-1106

Slaight Family Centre for Youth in Transition and Kimel Family Translational Imaging-Genetics Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1001/jamapsychiatry.2018.2410DOI Listing
November 2018

Care of Youth in Their First Emergency Presentation for Psychotic Disorder: A Population-Based Retrospective Cohort Study.

J Clin Psychiatry 2018 11 6;79(6). Epub 2018 Nov 6.

Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.4088/JCP.17m11947DOI Listing
November 2018

Resting state functional connectivity in patients with remitted psychotic depression: A multi-centre STOP-PD study.

EBioMedicine 2018 Oct 1;36:446-453. Epub 2018 Oct 1.

Kimel Family Translational Imaging-Genetics Laboratory, Research Imaging Centre, 250 College Street, Toronto, ON M5T 1R8, Canada; Campbell Family Mental Health Research Institute, 250 College Street, Toronto, ON M5T 1R8, Canada; Centre for Addiction and Mental Health, 250 College Street, Toronto, ON M5T 1R8, Canada; Department of Psychiatry, University of Toronto, 250 College Street, Toronto, ON M5T 1R8, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S23523964183038
Publisher Site
http://dx.doi.org/10.1016/j.ebiom.2018.09.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197617PMC
October 2018

Objective investigation of activity preference in schizophrenia: A pilot study.

Psychiatry Res 2018 09 16;267:551-559. Epub 2018 May 16.

Schizophrenia Division and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 250 College St., Toronto, Ontario M5T 1R8, Canada.; Institute of Medical Science, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada.; Department of Psychiatry, University of Toronto, 250 College St., Toronto, Ontario M5T 1R8, Canada.

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http://dx.doi.org/10.1016/j.psychres.2018.05.039DOI Listing
September 2018

Modeling and prediction of clinical symptom trajectories in Alzheimer's disease using longitudinal data.

PLoS Comput Biol 2018 09 14;14(9):e1006376. Epub 2018 Sep 14.

Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1371/journal.pcbi.1006376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157905PMC
September 2018

Personalized Intrinsic Network Topography Mapping and Functional Connectivity Deficits in Autism Spectrum Disorder.

Biol Psychiatry 2018 08 17;84(4):278-286. Epub 2018 Mar 17.

Kimel Family Translational Imaging Genetics Research Laboratory, The Centre for Addiction and Mental Health, University of Toronto, Toronto, Canada; Campbell Family Mental Health Research Institute, The Centre for Addiction and Mental Health, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2018.02.1174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076333PMC
August 2018

Subcortical volume and cortical surface architecture in women with acute and remitted anorexia nervosa: An exploratory neuroimaging study.

J Psychiatr Res 2018 07 13;102:179-185. Epub 2018 Apr 13.

Centre for Addiction and Mental Health, Toronto, ON, Canada; Institute of Medical Science, University of Toronto, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S00223956173120
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http://dx.doi.org/10.1016/j.jpsychires.2018.04.010DOI Listing
July 2018

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

Authors:
Jeanne E Savage Philip R Jansen Sven Stringer Kyoko Watanabe Julien Bryois Christiaan A de Leeuw Mats Nagel Swapnil Awasthi Peter B Barr Jonathan R I Coleman Katrina L Grasby Anke R Hammerschlag Jakob A Kaminski Robert Karlsson Eva Krapohl Max Lam Marianne Nygaard Chandra A Reynolds Joey W Trampush Hannah Young Delilah Zabaneh Sara Hägg Narelle K Hansell Ida K Karlsson Sten Linnarsson Grant W Montgomery Ana B Muñoz-Manchado Erin B Quinlan Gunter Schumann Nathan G Skene Bradley T Webb Tonya White Dan E Arking Dimitrios Avramopoulos Robert M Bilder Panos Bitsios Katherine E Burdick Tyrone D Cannon Ornit Chiba-Falek Andrea Christoforou Elizabeth T Cirulli Eliza Congdon Aiden Corvin Gail Davies Ian J Deary Pamela DeRosse Dwight Dickinson Srdjan Djurovic Gary Donohoe Emily Drabant Conley Johan G Eriksson Thomas Espeseth Nelson A Freimer Stella Giakoumaki Ina Giegling Michael Gill David C Glahn Ahmad R Hariri Alex Hatzimanolis Matthew C Keller Emma Knowles Deborah Koltai Bettina Konte Jari Lahti Stephanie Le Hellard Todd Lencz David C Liewald Edythe London Astri J Lundervold Anil K Malhotra Ingrid Melle Derek Morris Anna C Need William Ollier Aarno Palotie Antony Payton Neil Pendleton Russell A Poldrack Katri Räikkönen Ivar Reinvang Panos Roussos Dan Rujescu Fred W Sabb Matthew A Scult Olav B Smeland Nikolaos Smyrnis John M Starr Vidar M Steen Nikos C Stefanis Richard E Straub Kjetil Sundet Henning Tiemeier Aristotle N Voineskos Daniel R Weinberger Elisabeth Widen Jin Yu Goncalo Abecasis Ole A Andreassen Gerome Breen Lene Christiansen Birgit Debrabant Danielle M Dick Andreas Heinz Jens Hjerling-Leffler M Arfan Ikram Kenneth S Kendler Nicholas G Martin Sarah E Medland Nancy L Pedersen Robert Plomin Tinca J C Polderman Stephan Ripke Sophie van der Sluis Patrick F Sullivan Scott I Vrieze Margaret J Wright Danielle Posthuma

Nat Genet 2018 07 25;50(7):912-919. Epub 2018 Jun 25.

Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41588-018-0152-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411041PMC
July 2018

BDNF-Dependent Effects on Amygdala-Cortical Circuitry and Depression Risk in Children and Youth.

Cereb Cortex 2018 05;28(5):1760-1770

Research Imaging Centre, Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada M5T 1R8.

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http://dx.doi.org/10.1093/cercor/bhx086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907350PMC
May 2018

Objective assessment of exploratory behaviour in schizophrenia using wireless motion capture.

Schizophr Res 2018 05 24;195:122-129. Epub 2017 Sep 24.

Schizophrenia Division and Campbell Family Research Institute, Centre for Addiction and Mental Health, 250 College St., Toronto, Ontario M5T 1R8, Canada; Institute of Medical Science, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada; Department of Psychiatry, University of Toronto, 250 College St., Toronto, Ontario M5T 1R8, Canada.

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http://dx.doi.org/10.1016/j.schres.2017.09.011DOI Listing
May 2018

The Genetics of Endophenotypes of Neurofunction to Understand Schizophrenia (GENUS) consortium: A collaborative cognitive and neuroimaging genetics project.

Schizophr Res 2018 05 3;195:306-317. Epub 2017 Oct 3.

Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, United States; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States; Department of Psychiatry, Harvard Medical School, Boston, MA, United States; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2017.09.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882601PMC
May 2018

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Authors:
Gail Davies Max Lam Sarah E Harris Joey W Trampush Michelle Luciano W David Hill Saskia P Hagenaars Stuart J Ritchie Riccardo E Marioni Chloe Fawns-Ritchie David C M Liewald Judith A Okely Ari V Ahola-Olli Catriona L K Barnes Lars Bertram Joshua C Bis Katherine E Burdick Andrea Christoforou Pamela DeRosse Srdjan Djurovic Thomas Espeseth Stella Giakoumaki Sudheer Giddaluru Daniel E Gustavson Caroline Hayward Edith Hofer M Arfan Ikram Robert Karlsson Emma Knowles Jari Lahti Markus Leber Shuo Li Karen A Mather Ingrid Melle Derek Morris Christopher Oldmeadow Teemu Palviainen Antony Payton Raha Pazoki Katja Petrovic Chandra A Reynolds Muralidharan Sargurupremraj Markus Scholz Jennifer A Smith Albert V Smith Natalie Terzikhan Anbupalam Thalamuthu Stella Trompet Sven J van der Lee Erin B Ware B Gwen Windham Margaret J Wright Jingyun Yang Jin Yu David Ames Najaf Amin Philippe Amouyel Ole A Andreassen Nicola J Armstrong Amelia A Assareh John R Attia Deborah Attix Dimitrios Avramopoulos David A Bennett Anne C Böhmer Patricia A Boyle Henry Brodaty Harry Campbell Tyrone D Cannon Elizabeth T Cirulli Eliza Congdon Emily Drabant Conley Janie Corley Simon R Cox Anders M Dale Abbas Dehghan Danielle Dick Dwight Dickinson Johan G Eriksson Evangelos Evangelou Jessica D Faul Ian Ford Nelson A Freimer He Gao Ina Giegling Nathan A Gillespie Scott D Gordon Rebecca F Gottesman Michael E Griswold Vilmundur Gudnason Tamara B Harris Annette M Hartmann Alex Hatzimanolis Gerardo Heiss Elizabeth G Holliday Peter K Joshi Mika Kähönen Sharon L R Kardia Ida Karlsson Luca Kleineidam David S Knopman Nicole A Kochan Bettina Konte John B Kwok Stephanie Le Hellard Teresa Lee Terho Lehtimäki Shu-Chen Li Christina M Lill Tian Liu Marisa Koini Edythe London Will T Longstreth Oscar L Lopez Anu Loukola Tobias Luck Astri J Lundervold Anders Lundquist Leo-Pekka Lyytikäinen Nicholas G Martin Grant W Montgomery Alison D Murray Anna C Need Raymond Noordam Lars Nyberg William Ollier Goran Papenberg Alison Pattie Ozren Polasek Russell A Poldrack Bruce M Psaty Simone Reppermund Steffi G Riedel-Heller Richard J Rose Jerome I Rotter Panos Roussos Suvi P Rovio Yasaman Saba Fred W Sabb Perminder S Sachdev Claudia L Satizabal Matthias Schmid Rodney J Scott Matthew A Scult Jeannette Simino P Eline Slagboom Nikolaos Smyrnis Aïcha Soumaré Nikos C Stefanis David J Stott Richard E Straub Kjetil Sundet Adele M Taylor Kent D Taylor Ioanna Tzoulaki Christophe Tzourio André Uitterlinden Veronique Vitart Aristotle N Voineskos Jaakko Kaprio Michael Wagner Holger Wagner Leonie Weinhold K Hoyan Wen Elisabeth Widen Qiong Yang Wei Zhao Hieab H H Adams Dan E Arking Robert M Bilder Panos Bitsios Eric Boerwinkle Ornit Chiba-Falek Aiden Corvin Philip L De Jager Stéphanie Debette Gary Donohoe Paul Elliott Annette L Fitzpatrick Michael Gill David C Glahn Sara Hägg Narelle K Hansell Ahmad R Hariri M Kamran Ikram J Wouter Jukema Eero Vuoksimaa Matthew C Keller William S Kremen Lenore Launer Ulman Lindenberger Aarno Palotie Nancy L Pedersen Neil Pendleton David J Porteous Katri Räikkönen Olli T Raitakari Alfredo Ramirez Ivar Reinvang Igor Rudan Dan Rujescu Reinhold Schmidt Helena Schmidt Peter W Schofield Peter R Schofield John M Starr Vidar M Steen Julian N Trollor Steven T Turner Cornelia M Van Duijn Arno Villringer Daniel R Weinberger David R Weir James F Wilson Anil Malhotra Andrew M McIntosh Catharine R Gale Sudha Seshadri Thomas H Mosley Jan Bressler Todd Lencz Ian J Deary

Nat Commun 2018 05 29;9(1):2098. Epub 2018 May 29.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1038/s41467-018-04362-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974083PMC
May 2018

Manual segmentation of the fornix, fimbria, and alveus on high-resolution 3T MRI: Application via fully-automated mapping of the human memory circuit white and grey matter in healthy and pathological aging.

Neuroimage 2018 04 18;170:132-150. Epub 2016 Oct 18.

Computational Brain Anatomy Laboratory, Cerebral Imaging Centre, Douglas Mental Health University Institute, Montreal, Canada; Integrated Program in Neuroscience, McGill University, Montreal, Canada; Department of Psychiatry, McGill University, Montreal, Canada; Department of Biological and Biomedical Engineering, McGill University, Montreal, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2016.10.027DOI Listing
April 2018

A novel DTI-QA tool: Automated metric extraction exploiting the sphericity of an agar filled phantom.

Magn Reson Imaging 2018 02 17;46:28-39. Epub 2017 Oct 17.

Centre for Addiction and Mental Health, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada; Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Toronto, Canada.

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http://dx.doi.org/10.1016/j.mri.2017.07.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800507PMC
February 2018

Genetic influence of plasma homocysteine on Alzheimer's disease.

Neurobiol Aging 2018 02 13;62:243.e7-243.e14. Epub 2017 Oct 13.

Kimel Family Translational Imaging-Genetics Laboratory, Research Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Underserved Populations Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.09.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953632PMC
February 2018

Age and gender interactions in white matter of schizophrenia and obsessive compulsive disorder compared to non-psychiatric controls: commonalities across disorders.

Brain Imaging Behav 2017 Dec;11(6):1836-1848

Centre for Addiction and Mental Health, Campbell Family Mental Health Research Institute, Unit 4-1, Office 125, 1001 Queen Street West, Toronto, ON, M6J 1H4, Canada.

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http://dx.doi.org/10.1007/s11682-016-9657-8DOI Listing
December 2017

Gray Matter Neuritic Microstructure Deficits in Schizophrenia and Bipolar Disorder.

Biol Psychiatry 2017 Nov 8;82(10):726-736. Epub 2016 Dec 8.

Kimel Family Translational Imaging-Genetics Laboratory, Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Research Imaging Centre, Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2016.12.005DOI Listing
November 2017

Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.

Cell Rep 2017 Nov;21(9):2597-2613

Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA; Department of Psychiatry, Hofstra Northwell School of Medicine, Hempstead, NY, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.11.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789458PMC
November 2017

Genetic epistasis regulates amyloid deposition in resilient aging.

Alzheimers Dement 2017 Oct 17;13(10):1107-1116. Epub 2017 Mar 17.

Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.01.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601013PMC
October 2017

Machine Learning for Large-Scale Quality Control of 3D Shape Models in Neuroimaging.

Mach Learn Med Imaging 2017 Sep 7;10541:371-378. Epub 2017 Sep 7.

Imaging Genetics Center, Stevens Institute for Neuroimaging and Informatics, University of Southern California, Marina Del Rey, CA, USA.

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http://link.springer.com/10.1007/978-3-319-67389-9_43
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http://dx.doi.org/10.1007/978-3-319-67389-9_43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049825PMC
September 2017

Investigating consummatory and anticipatory pleasure across motivation deficits in schizophrenia and healthy controls.

Psychiatry Res 2017 08 23;254:112-117. Epub 2017 Apr 23.

Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S01651781163210
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http://dx.doi.org/10.1016/j.psychres.2017.04.040DOI Listing
August 2017

Brain-Derived Neurotrophic Factor Expression in Individuals With Schizophrenia and Healthy Aging: Testing the Accelerated Aging Hypothesis of Schizophrenia.

Curr Psychiatry Rep 2017 Jul;19(7):36

Division of Geriatric Psychiatry, Department of Psychiatry, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s11920-017-0794-6DOI Listing
July 2017

Objective assessment of exploratory behaviour in schizophrenia using wireless motion capture.

Schizophr Res 2018 05 24;195:122-129. Epub 2017 Sep 24.

Schizophrenia Division and Campbell Family Research Institute, Centre for Addiction and Mental Health, 250 College St., Toronto, Ontario M5T 1R8, Canada; Institute of Medical Science, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada; Department of Psychiatry, University of Toronto, 250 College St., Toronto, Ontario M5T 1R8, Canada.

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http://dx.doi.org/10.1016/j.schres.2017.09.011DOI Listing
May 2018

Insight Into Illness and Cognition in Schizophrenia in Earlier and Later Life.

J Clin Psychiatry 2017 04;78(4):e390-e397

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada.

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http://dx.doi.org/10.4088/JCP.16m10741DOI Listing
April 2017

Neural Activity while Imitating Emotional Faces is Related to Both Lower and Higher-Level Social Cognitive Performance.

Sci Rep 2017 04 28;7(1):1244. Epub 2017 Apr 28.

Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, 250 College St., Toronto, M5T 1R8, ON, Canada.

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http://dx.doi.org/10.1038/s41598-017-01316-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430668PMC
April 2017

CERES: A new cerebellum lobule segmentation method.

Neuroimage 2017 02 8;147:916-924. Epub 2016 Nov 8.

Instituto de Aplicaciones de las Tecnologías de la Información y de las Comunicaciones Avanzadas (ITACA), Universitat Politècnica de València, Camino de Vera s/n, 46022 Valencia, Spain.

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http://dx.doi.org/10.1016/j.neuroimage.2016.11.003DOI Listing
February 2017

Association study between the neurexin-1 gene and tardive dyskinesia.

Hum Psychopharmacol 2017 01;32(1)

Neurogenetics Section, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/hup.2568DOI Listing
January 2017

A Diffusion Tensor Imaging Study in Children With ADHD, Autism Spectrum Disorder, OCD, and Matched Controls: Distinct and Non-Distinct White Matter Disruption and Dimensional Brain-Behavior Relationships.

Am J Psychiatry 2016 Dec 1;173(12):1213-1222. Epub 2016 Jul 1.

From the Centre for Brain and Mental Health and the Department of Diagnostic Imaging, the Hospital for Sick Children, University of Toronto; the Department of Psychology, University of Toronto; the Department of Psychiatry, the Department of Medical Biophysics, the Department of Pediatrics, and the Department of Medical Imaging, Faculty of Medicine, University of Toronto; the Holland Bloorview Kids Rehabilitation Hospital, Bloorview Research Institute, University of Toronto; the Margaret and Wallace McCain Centre for Child, Youth & Family Mental Health and the Kimel Family Translational Imaging-Genetics Lab, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), University of Toronto; the Division of Child and Adolescent Psychiatry, Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minn.; the Pediatric OCD Consultation Service, Anxiety Treatment and Research Centre, St. Joseph's HealthCare, McMaster University, Hamilton, Ont., Canada; and the Mathison Centre for Mental Health Research and Education, Hotchkiss Brain Institute, the Department of Psychiatry, and the Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Alta., Canada.

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http://dx.doi.org/10.1176/appi.ajp.2016.15111435DOI Listing
December 2016

An optimal combination of MCCB and CANTAB to assess functional capacity in older individuals with schizophrenia.

Int J Geriatr Psychiatry 2016 10 18;31(10):1116-23. Epub 2016 Jul 18.

Division of Geriatric Psychiatry, Centre for Addiction and Mental Health, Toronto, Canada.

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http://dx.doi.org/10.1002/gps.4547DOI Listing
October 2016

Prefrontal White Matter Structure Mediates the Influence of GAD1 on Working Memory.

Neuropsychopharmacology 2016 08 29;41(9):2224-31. Epub 2016 Jan 29.

Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/npp.2016.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946050PMC
August 2016

Manual-Protocol Inspired Technique for Improving Automated MR Image Segmentation during Label Fusion.

Front Neurosci 2016 19;10:325. Epub 2016 Jul 19.

Institute of Biomaterials and Biomedical Engineering, University of TorontoToronto, ON, Canada; Cerebral Imaging Centre, Douglas Mental Health University InstituteVerdun, QC, Canada; Department of Psychiatry, McGill UniversityMontreal, QC, Canada; Biological and Biomedical Engineering, McGill UniversityMontreal, QC, Canada.

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http://dx.doi.org/10.3389/fnins.2016.00325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949270PMC
August 2016

Limited Evidence for Association of Genome-Wide Schizophrenia Risk Variants on Cortical Neuroimaging Phenotypes.

Schizophr Bull 2016 07 27;42(4):1027-36. Epub 2015 Dec 27.

Zucker Hillside Hospital, Glen Oaks, NY; Center for Psychiatric Neuroscience, Feinstein Institute, Manhasset, NY.

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http://dx.doi.org/10.1093/schbul/sbv180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4903045PMC
July 2016

Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant.

J Cereb Blood Flow Metab 2016 Apr 13;36(4):819-30. Epub 2016 Jan 13.

Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, ON, Canada Institute of Medical Science, University of Toronto, King's College Circle, Toronto, ON, Canada

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http://dx.doi.org/10.1177/0271678X15626719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821029PMC
April 2016

The influence of medical burden severity and cognition on functional competence in older community-dwelling individuals with schizophrenia.

Schizophr Res 2016 Feb 24;170(2-3):330-5. Epub 2015 Dec 24.

Division of Geriatric Psychiatry, Centre for Addiction and Mental Health, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2015.12.009DOI Listing
February 2016

Channelopathy-related SCN10A gene variants predict cerebellar dysfunction in multiple sclerosis.

Neurology 2016 Feb 6;86(5):410-7. Epub 2016 Jan 6.

From the MS Research Center, Neuroscience Institute (T.R., S.S., Aria Nazeri, S.N., M.N., A.N.M., M.O., R.D., A.A., Arash Nazeri, M.A.S.), Interdisciplinary Neuroscience Research Program (T.R., S.S., M.N., Arash Nazeri), Urology Research Center (R.M.), Department of Neurology (A.N.M., M.A.S.), and Department of Radiology (A.P.H.T., A.S.R.), Tehran University of Medical Sciences, Iran; Kimel Family Translational Imaging-Genetics Laboratory (T.R., A.N.V., Arash Nazeri), Research Imaging Centre, Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Toronto; Department of Psychiatry (T.R., A.N.V., Arash Nazeri), University of Toronto; Cerebral Imaging Centre (M.T.M.P., M.M.C.), Douglas Mental Health Institute, Verdun; Schulich School of Medicine and Dentistry (M.T.M.P.), Western University, London, Canada; Department of Electrical Engineering (M.J.S.), Sharif University of Technology, Tehran, Iran; Department of Neurology (A.A.), Thomas Jefferson University, Philadelphia, PA; and Departments of Psychiatry and Biomedical Engineering (M.M.C.), McGill University, Montreal, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000002326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773947PMC
February 2016

Neuroimaging predictors of functional outcomes in schizophrenia at baseline and 6-month follow-up.

Schizophr Res 2015 Dec 24;169(1-3):69-75. Epub 2015 Oct 24.

Kimel Family Translational Imaging-Genetics Research Lab, Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, ON M5T 1R8, Canada; Institute of Medical Science, University of Toronto, 27 King's College Circle, Toronto, ON M5S, Canada; Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, 250 College Street, Toronto, ON M5T 1R8, Canada; Department of Psychiatry, University of Toronto, 27 King's College Circle, Toronto, ON, M5S, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2015.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681643PMC
December 2015

Genome-wide variant by serum urate interaction in Parkinson's disease.

Ann Neurol 2015 Nov 29;78(5):731-41. Epub 2015 Aug 29.

Kimel Family Translational Imaging-Genetics Laboratory, Research Imaging Centre, Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/ana.24504DOI Listing
November 2015

High-resolution In Vivo Manual Segmentation Protocol for Human Hippocampal Subfields Using 3T Magnetic Resonance Imaging.

J Vis Exp 2015 Nov 10(105):e51861. Epub 2015 Nov 10.

Institute of Biomaterials and Biomedical Engineering, University of Toronto; Computational Brain Anatomy Laboratory, Douglas Institute, McGill University.

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http://dx.doi.org/10.3791/51861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692694PMC
November 2015

Hippocampal (subfield) volume and shape in relation to cognitive performance across the adult lifespan.

Hum Brain Mapp 2015 Aug 9;36(8):3020-37. Epub 2015 May 9.

Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/hbm.22825DOI Listing
August 2015

Superficial white matter as a novel substrate of age-related cognitive decline.

Neurobiol Aging 2015 Jun 27;36(6):2094-106. Epub 2015 Feb 27.

Kimel Family Translational Imaging-Genetics Laboratory, Ontario, Canada; Research Imaging Centre, Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Geriatric Mental Health Service, Centre for Addiction and Mental Health, Ontario, Canada; Institute of Medical Science, University of Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.02.022DOI Listing
June 2015

Further neuroimaging evidence for the deficit subtype of schizophrenia: a cortical connectomics analysis.

JAMA Psychiatry 2015 May;72(5):446-55

Kimel Family Translational Imaging Genetics Laboratory, Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada2Schizophrenia Division of the Complex Mental Illness Program, Centre for Addiction and Mental Health, Toronto.

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http://dx.doi.org/10.1001/jamapsychiatry.2014.3020DOI Listing
May 2015

The impact of aging, cognition, and symptoms on functional competence in individuals with schizophrenia across the lifespan.

Schizophr Bull 2015 Mar 6;41(2):374-81. Epub 2014 Aug 6.

Division of Geriatric Psychiatry, Centre for Addiction and Mental Health, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada;

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http://dx.doi.org/10.1093/schbul/sbu114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332950PMC
March 2015

Minimal evidence that untreated psychosis damages brain structures: a systematic review.

Schizophr Res 2015 Mar 30;162(1-3):222-33. Epub 2015 Jan 30.

Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario M5T 1R8, Canada; Department of Psychiatry, University of Toronto, 250 College Street, Toronto, Ontario M5T 1R8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2015.01.021DOI Listing
March 2015

Functional consequences of neurite orientation dispersion and density in humans across the adult lifespan.

J Neurosci 2015 Jan;35(4):1753-62

Kimel Family Translational Imaging-Genetics Laboratory, Research Imaging Centre, Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada M5T 1R8, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada M5T 1R8, Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada M5S 1A8, Geriatric Mental Health Service, Centre for Addiction and Mental Health, Toronto, Ontario, Canada M6J 1H4,

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.3979-14.2
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http://dx.doi.org/10.1523/JNEUROSCI.3979-14.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308611PMC
January 2015

Quantitative imaging of neuroinflammation in human white matter: a positron emission tomography study with translocator protein 18 kDa radioligand, [18F]-FEPPA.

Synapse 2014 Nov 28;68(11):536-47. Epub 2014 Jul 28.

Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, M5T 1R8, Canada; Institute of Medical Science, University of Toronto, Ontario, M5S 1A8, Canada.

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http://dx.doi.org/10.1002/syn.21765DOI Listing
November 2014

The role of untreated psychosis in neurodegeneration: a review of hypothesized mechanisms of neurotoxicity in first-episode psychosis.

Can J Psychiatry 2014 Oct;59(10):513-7

Medical Director and Director of Health Equity, Centre for Addiction and Mental Health, Toronto, Ontario; Co-Director of Equity, Gender, and Population Psychiatry and Professor, Department of Psychiatry, University of Toronto, Toronto, Ontario.

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http://journals.sagepub.com/doi/10.1177/070674371405901003
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197784PMC
http://dx.doi.org/10.1177/070674371405901003DOI Listing
October 2014

A review of structural neuroimaging in schizophrenia: from connectivity to connectomics.

Front Hum Neurosci 2014 25;8:653. Epub 2014 Aug 25.

Kimel Family Translational Imaging Genetics Laboratory, Centre for Addiction and Mental Health, Research Imaging Centre Toronto, ON, Canada ; Department of Psychiatry, University of Toronto Toronto, ON, Canada.

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http://dx.doi.org/10.3389/fnhum.2014.00653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142355PMC
September 2014