Publications by authors named "Aris N Economides"

71Publications

Activin A does not drive post-traumatic heterotopic ossification.

Bone 2020 Sep 15;138:115473. Epub 2020 Jun 15.

Department of Surgery, University of Michigan, Ann Arbor, MI, United States of America; Division of Plastic Surgery, Department of Surgery, University of Michigan Health System, 1500 E Medical Center Drive, SPC 5340, Ann Arbor, MI 48109-5340, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2020.115473DOI Listing
September 2020

Effects of BMP7 produced by group 2 innate lymphoid cells on adipogenesis.

Int Immunol 2020 05;32(6):407-419

Laboratory for Innate Immune Systems, RIKEN Center for Integrative Medical Sciences (IMS), Tsurumi-ku, Yokohama, Kanagawa, Japan.

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http://dx.doi.org/10.1093/intimm/dxaa013DOI Listing
May 2020

Odd skipped-related 1 (Osr1) identifies muscle-interstitial fibro-adipogenic progenitors (FAPs) activated by acute injury.

Stem Cell Res 2018 10 10;32:8-16. Epub 2018 Aug 10.

Institute of Chemistry and Biochemistry, Freie Universität Berlin, 14195 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2018.08.010DOI Listing
October 2018

Induction of the Hajdu-Cheney Syndrome Mutation in CD19 B Cells in Mice Alters B-Cell Allocation but Not Skeletal Homeostasis.

Am J Pathol 2018 06 12;188(6):1430-1446. Epub 2018 Mar 12.

Department of Orthopaedic Surgery, UConn Health, Farmington, Connecticut; UConn Musculoskeletal Institute, UConn Health, Farmington, Connecticut; Department of Medicine, UConn Health, Farmington, Connecticut. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2018.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971225PMC
June 2018

SOST/Sclerostin Improves Posttraumatic Osteoarthritis and Inhibits MMP2/3 Expression After Injury.

J Bone Miner Res 2018 06 2;33(6):1105-1113. Epub 2018 Apr 2.

Lawrence Livermore National Laboratories, Physical and Life Sciences Directorate, Livermore, CA, USA.

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http://dx.doi.org/10.1002/jbmr.3397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033030PMC
June 2018

Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts.

PLoS One 2017 27;12(11):e0188264. Epub 2017 Nov 27.

Lawrence Livermore National Laboratories, Physical and Life Sciences Directorate, Livermore, CA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0188264PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703471PMC
December 2017

The obligatory role of Activin A in the formation of heterotopic bone in Fibrodysplasia Ossificans Progressiva.

Bone 2018 04 16;109:210-217. Epub 2017 Jun 16.

Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY 10591, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2017.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706059PMC
April 2018

Sostdc1 deficiency accelerates fracture healing by promoting the expansion of periosteal mesenchymal stem cells.

Bone 2016 07 19;88:20-30. Epub 2016 Apr 19.

Biology and Biotechnology Division, Lawrence Livermore National Laboratory, 7000 East Avenue, L-452, Livermore, CA 94550, USA; Molecular and Cell Biology Unit, School of Natural Sciences, University of California at Merced, Merced, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2016.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277141PMC
July 2016

Global molecular changes in a tibial compression induced ACL rupture model of post-traumatic osteoarthritis.

J Orthop Res 2017 03 10;35(3):474-485. Epub 2016 May 10.

Lawrence Livermore National Laboratories, Physical and Life Sciences Directorate, 7000 East Ave, L-452, Livermore, California, 94550.

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http://dx.doi.org/10.1002/jor.23263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363336PMC
March 2017

Sclerostin antibody treatment improves fracture outcomes in a Type I diabetic mouse model.

Bone 2016 Jan 5;82:122-34. Epub 2015 May 5.

School of Natural Sciences, University of California, Merced, Merced, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2015.04.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635060PMC
January 2016

Elimination of BMP7 from the developing limb mesenchyme leads to articular cartilage degeneration and synovial inflammation with increased age.

FEBS Lett 2015 May 15;589(11):1240-8. Epub 2015 Apr 15.

Department of Cartilage Regeneration, Graduate School, Tokyo Medical and Dental University, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.febslet.2015.04.004DOI Listing
May 2015

Removal of SOST or blocking its product sclerostin rescues defects in the periodontitis mouse model.

FASEB J 2015 Jul 10;29(7):2702-11. Epub 2015 Mar 10.

*Department of Biomedical Sciences, Texas A&M University Baylor College of Dentistry, Dallas, Texas, USA; State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Sichuan, China; Department of Preventive and Restorative Dental Sciences, University of California, San Francisco, San Francisco, California, USA; Department of Periodontics, University of Texas Health Science Center, San Antonio, San Antonio, Texas, USA; The State Key Laboratory Breeding Base of Basic Science of Stomatology & Key Laboratory of Oral Biomedicine, School & Hospital of Stomatology, Wuhan University, Wuhan, China; Regeneron Pharmaceuticals, Tarrytown, New York, USA; and Department of Metabolic Disorders, Amgen Incorporated, Thousand Oaks, California, USA

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http://www.fasebj.org/content/29/7/2702.full.pdf
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http://www.fasebj.org/cgi/doi/10.1096/fj.14-265496
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http://dx.doi.org/10.1096/fj.14-265496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478802PMC
July 2015

microTSS: accurate microRNA transcription start site identification reveals a significant number of divergent pri-miRNAs.

Nat Commun 2014 Dec 10;5:5700. Epub 2014 Dec 10.

Department of Electrical and Computer Engineering, University of Thessaly, 38221 Volos, Greece.

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http://dx.doi.org/10.1038/ncomms6700DOI Listing
December 2014

Sox2 acts as a rheostat of epithelial to mesenchymal transition during neural crest development.

Front Physiol 2014 12;5:345. Epub 2014 Sep 12.

Stem Cell Biology Laboratory, Division of Molecular Biology and Genetics, Biomedical Sciences Research Centre "Alexander Fleming" Vari-Attica, Greece.

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http://dx.doi.org/10.3389/fphys.2014.00345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162359PMC
October 2014

Noncoding RNA transcription targets AID to divergently transcribed loci in B cells.

Nature 2014 Oct 6;514(7522):389-93. Epub 2014 Aug 6.

Department of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1038/nature13580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372240PMC
October 2014

Sost and its paralog Sostdc1 coordinate digit number in a Gli3-dependent manner.

Dev Biol 2013 Nov 29;383(1):90-105. Epub 2013 Aug 29.

Biology and Biotechnology Division, Lawrence Livermore National Laboratory, 7000 East Avenue, L-452, Livermore, CA 94550, USA.

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http://dx.doi.org/10.1016/j.ydbio.2013.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861057PMC
November 2013

Application of a novel strategy of engineering conditional alleles to a single exon gene, Sox2.

PLoS One 2012 27;7(9):e45768. Epub 2012 Sep 27.

Stem Cell Biology Laboratory, Institute of Molecular Biology and Genetics, Biomedical Sciences Research Centre Alexander Fleming, Vari, Greece.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0045768PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459942PMC
February 2013

Targeted deletion of Sost distal enhancer increases bone formation and bone mass.

Proc Natl Acad Sci U S A 2012 Aug 10;109(35):14092-7. Epub 2012 Aug 10.

Physical and Life Sciences Directorate, Lawrence Livermore National Laboratories, Livermore, CA 94550, USA.

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http://dx.doi.org/10.1073/pnas.1207188109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435175PMC
August 2012

Inactivation of the dual Bmp/Wnt inhibitor Sostdc1 enhances pancreatic islet function.

Am J Physiol Endocrinol Metab 2012 Sep 24;303(6):E752-61. Epub 2012 Jul 24.

Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232-0475, USA.

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http://dx.doi.org/10.1152/ajpendo.00531.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468431PMC
September 2012

Connective tissue growth factor acts within both endothelial cells and beta cells to promote proliferation of developing beta cells.

Proc Natl Acad Sci U S A 2011 Sep 29;108(37):15242-7. Epub 2011 Aug 29.

Department of Molecular Physiology and Biophysics, Division of Diabetes, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1073/pnas.1100072108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174622PMC
September 2011

Loss of gremlin delays primordial follicle assembly but does not affect female fertility in mice.

Biol Reprod 2011 Dec 10;85(6):1175-82. Epub 2011 Aug 10.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA.

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http://dx.doi.org/10.1095/biolreprod.111.091728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223251PMC
December 2011

Genetic evidence points to an osteocalcin-independent influence of osteoblasts on energy metabolism.

J Bone Miner Res 2011 Sep;26(9):2012-25

Department of Medicine, Division of Endocrinology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.1002/jbmr.417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656486PMC
September 2011

Cooperative activity of noggin and gremlin 1 in axial skeleton development.

Development 2011 Mar;138(5):1005-14

Department of Molecular and Cell Biology and Center for Integrative Genomics, University of California, Berkeley, CA 94720, USA.

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http://dx.doi.org/10.1242/dev.051938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035099PMC
March 2011

Distinct modes of inhibition by sclerostin on bone morphogenetic protein and Wnt signaling pathways.

J Biol Chem 2010 Dec 15;285(53):41614-26. Epub 2010 Oct 15.

Department of Molecular Cell Biology and Centre for Biomedical Genetics, Julius-von-Sachs Institut für Biowissenschaften der UniversitätWürzburg, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1074/jbc.M110.153890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009889PMC
December 2010

Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region.

Proc Natl Acad Sci U S A 2010 Aug 26;107(32):14211-6. Epub 2010 Jul 26.

Development and Disease Group, Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany.

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http://dx.doi.org/10.1073/pnas.1009314107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922544PMC
August 2010

Connective tissue growth factor is required for skeletal development and postnatal skeletal homeostasis in male mice.

Endocrinology 2010 Aug 9;151(8):3490-501. Epub 2010 Jun 9.

Department of Research, Saint Francis Hospital and Medical Center, Hartford, Connecticut 06105-1299, USA.

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http://dx.doi.org/10.1210/en.2010-0145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940511PMC
August 2010

Nephroblastoma overexpressed (Nov) inactivation sensitizes osteoblasts to bone morphogenetic protein-2, but nov is dispensable for skeletal homeostasis.

Endocrinology 2010 Jan 24;151(1):221-33. Epub 2009 Nov 24.

Department of Research, Saint Francis Hospital and Medical Center, 114 Woodland Street, Hartford, Connecticut 06105-1299, USA.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2009-0574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803142PMC
January 2010

Generation and functional characterization of mice with a conditional BMP7 allele.

Int J Dev Biol 2009 ;53(4):597-603

Institute of Immunology, Biomedical Sciences Research Center Al. Fleming, Vari 166 72, Hellas/Greece.

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http://dx.doi.org/10.1387/ijdb.082648vzDOI Listing
August 2009

Podocyte-derived BMP7 is critical for nephron development.

J Am Soc Nephrol 2008 Nov 15;19(11):2181-91. Epub 2008 Oct 15.

Division of Nephrology, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1681/ASN.2007111212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573017PMC
November 2008

Conditional deletion of gremlin causes a transient increase in bone formation and bone mass.

J Biol Chem 2007 Oct 4;282(43):31549-57. Epub 2007 Sep 4.

Department of Research, Saint Francis Hospital and Medical Center, Hartford, Connecticut 06105-1299, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M701317200
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http://dx.doi.org/10.1074/jbc.M701317200DOI Listing
October 2007

Twisted gastrulation, a bone morphogenetic protein agonist/antagonist, is not required for post-natal skeletal function.

Bone 2006 Dec 24;39(6):1252-60. Epub 2006 Aug 24.

Department of Research, Saint Francis Hospital and Medical Center, Hartford, CT 06105-1299, USA.

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http://dx.doi.org/10.1016/j.bone.2006.06.028DOI Listing
December 2006

Skeletal overexpression of gremlin impairs bone formation and causes osteopenia.

Endocrinology 2005 Feb 11;146(2):655-65. Epub 2004 Nov 11.

Department of Research, Saint Francis Hospital and Medical Center, 114 Woodland Street, Hartford, Connecticut 06105-1299, USA.

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http://dx.doi.org/10.1210/en.2004-0766DOI Listing
February 2005

Bone morphogenetic proteins, their antagonists, and the skeleton.

Endocr Rev 2003 Apr;24(2):218-35

Department of Research, Saint Francis Hospital and Medical Center, Hartford, Connecticut 06105, USA.

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http://dx.doi.org/10.1210/er.2002-0023DOI Listing
April 2003

The BMP antagonist noggin regulates cranial suture fusion.

Nature 2003 Apr;422(6932):625-9

Department of Surgery, Stanford University School of Medicine, Stanford, California 94305-5148, USA.

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http://www.nature.com/articles/nature01545
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http://dx.doi.org/10.1038/nature01545DOI Listing
April 2003

Structural basis of BMP signalling inhibition by the cystine knot protein Noggin.

Nature 2002 Dec;420(6916):636-42

Structural Biology, Salk Institute, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/nature01245DOI Listing
December 2002

Heparan sulfate proteoglycans retain Noggin at the cell surface: a potential mechanism for shaping bone morphogenetic protein gradients.

J Biol Chem 2002 Jan 12;277(3):2089-96. Epub 2001 Nov 12.

Department of Pediatrics, Washington University School of Medicine and St. Louis Children's Hospital, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1074/jbc.M109151200DOI Listing
January 2002