Ari Melnick

Ari Melnick

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Ari Melnick

Publications by authors named "Ari Melnick"

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Rationale for targeting BCL6 in -rearranged acute lymphoblastic leukemia.

Genes Dev 2019 09 8;33(17-18):1265-1279. Epub 2019 Aug 8.

Department of Systems Biology, City of Hope Comprehensive Cancer Center, Monrovia, California 91016, USA.

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http://dx.doi.org/10.1101/gad.327593.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719625PMC
September 2019

An "EZ" Epigenetic Road to Leukemia Stem Cell Metabolic Reprogramming?

Cancer Discov 2019 Sep;9(9):1158-1160

Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, New York.

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http://dx.doi.org/10.1158/2159-8290.CD-19-0737DOI Listing
September 2019

Emerging epigenetic-modulating therapies in lymphoma.

Nat Rev Clin Oncol 2019 08;16(8):494-507

Department of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/s41571-019-0190-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650343PMC
August 2019

Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation.

Cancer Cell 2019 Aug;36(2):194-209.e9

Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A(∗)STAR), Singapore 138673, Singapore; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119077, Singapore; Department of Oncological Sciences and Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pharmacological Sciences and Mount Sinai Center for Therapeutics Discovery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.07.003DOI Listing
August 2019

Role of chromosomal architecture in germinal center B cells and lymphomagenesis.

Curr Opin Hematol 2019 Jul;26(4):294-302

Division of Hematology and Medical Oncology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Sandra and Edward Meyer Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1097/MOH.0000000000000505DOI Listing
July 2019

Quinoline and thiazolopyridine allosteric inhibitors of MALT1.

Bioorg Med Chem Lett 2019 Jul 20;29(14):1694-1698. Epub 2019 May 20.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, 360 Longwood Ave, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.bmcl.2019.05.040DOI Listing
July 2019

Peptide-based covalent inhibitors of MALT1 paracaspase.

Bioorg Med Chem Lett 2019 Jun 29;29(11):1336-1339. Epub 2019 Mar 29.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, 360 Longwood Ave, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2019.03.046DOI Listing
June 2019

BCL6 modulates tissue neutrophil survival and exacerbates pulmonary inflammation following influenza virus infection.

Proc Natl Acad Sci U S A 2019 Jun 28;116(24):11888-11893. Epub 2019 May 28.

Thoracic Diseases Research Unit, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905;

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http://dx.doi.org/10.1073/pnas.1902310116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6575592PMC
June 2019

Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis.

Cancer Cell 2019 Jun;35(6):916-931.e9

Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.05.002DOI Listing
June 2019

Ex vivo synthetic immune tissues with T cell signals for differentiating antigen-specific, high affinity germinal center B cells.

Biomaterials 2019 Apr 26;198:27-36. Epub 2018 Jun 26.

Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY, 14853, USA; Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY, 14853, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, 10021, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2018.06.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355359PMC
April 2019

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.

Science 2019 04;364(6436)

Northwestern University, Evanston, IL, USA.

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http://dx.doi.org/10.1126/science.aau8650DOI Listing
April 2019

Germinal center-derived lymphomas: The darkest side of humoral immunity.

Immunol Rev 2019 03;288(1):214-239

Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York City, New York.

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http://dx.doi.org/10.1111/imr.12755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518944PMC
March 2019

The Impact of Heterogeneity on Single-Cell Sequencing.

Front Genet 2019 1;10. Epub 2019 Mar 1.

Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY, United States.

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http://dx.doi.org/10.3389/fgene.2019.00008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405636PMC
March 2019

Untangling the Role of Polycomb Complexes in Chemotherapy Resistance.

Cancer Discov 2018 11;8(11):1348-1351

Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, New York.

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http://cancerdiscovery.aacrjournals.org/lookup/doi/10.1158/2
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http://dx.doi.org/10.1158/2159-8290.CD-18-1080DOI Listing
November 2018

Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth.

J Clin Invest 2018 10 19;128(10):4397-4412. Epub 2018 Jul 19.

Division of Hematology and Oncology, Department of Medicine, Weill Cornell Medicine, Cornell University, New York, New York, USA.

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http://dx.doi.org/10.1172/JCI99436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159983PMC
October 2018

Identification of Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design.

J Med Chem 2018 09 17;61(17):7573-7588. Epub 2018 Jul 17.

Department of Pharmaceutical Sciences , University of Maryland School of Pharmacy , 20 Penn Street , Baltimore , Maryland 21201 , United States.

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http://dx.doi.org/10.1021/acs.jmedchem.8b00040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334293PMC
September 2018

How Biophysical Forces Regulate Human B Cell Lymphomas.

Cell Rep 2018 Apr;23(2):499-511

Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA; Nancy E. and Peter C. Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA; Englander Institute for Precision Medicine, Weill Cornell Medical College, New York, NY 10021, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.03.069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965297PMC
April 2018

Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity.

Cancer Cell 2018 01 21;33(1):44-59.e8. Epub 2017 Dec 21.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15356108173051
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http://dx.doi.org/10.1016/j.ccell.2017.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760367PMC
January 2018

Follicular lymphoma: State-of-the-art ICML workshop in Lugano 2015.

Hematol Oncol 2017 Dec 4;35(4):397-407. Epub 2017 Apr 4.

Oncology Institute of Southern Switzerland, Ospedale San Giovanni, Bellinzona, Switzerland.

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http://dx.doi.org/10.1002/hon.2411DOI Listing
December 2017

Central role of myeloid MCPIP1 in protecting against LPS-induced inflammation and lung injury.

Signal Transduct Target Ther 2017 8;2:17066. Epub 2017 Dec 8.

Department of Biomedical Science and Shock/Trauma Research Center, School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, MO, USA.

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http://dx.doi.org/10.1038/sigtrans.2017.66DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721545PMC
December 2017

The N-methyladenosine (mA)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells.

Nat Med 2017 Nov 18;23(11):1369-1376. Epub 2017 Sep 18.

Molecular Pharmacology Program, Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1038/nm.4416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677536PMC
November 2017

Untangling the Web of Lymphoma Somatic Mutations.

Cell 2017 10;171(2):270-272

Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.09.031DOI Listing
October 2017

EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop.

Nat Commun 2017 10 12;8(1):877. Epub 2017 Oct 12.

Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, 10021, USA.

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http://dx.doi.org/10.1038/s41467-017-01029-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638898PMC
October 2017

Effective Combination Therapies for B-cell Lymphoma Predicted by a Virtual Disease Model.

Cancer Res 2017 04 27;77(8):1818-1830. Epub 2017 Jan 27.

Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medicine, New York, New York.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-0476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392381PMC
April 2017

DNA Methylation-Based Biomarkers.

J Clin Oncol 2017 03 23;35(7):793-795. Epub 2017 Jan 23.

Leandro Cerchietti and Ari Melnick, Weill Cornell Medicine, New York, NY.

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http://dx.doi.org/10.1200/JCO.2016.71.0616DOI Listing
March 2017

The Expanding Role of the BCL6 Oncoprotein as a Cancer Therapeutic Target.

Clin Cancer Res 2017 Feb 23;23(4):885-893. Epub 2016 Nov 23.

Department of Hematology/Oncology, Weill Cornell Medicine, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-2071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315622PMC
February 2017

General Biomarker Recommendations for Lymphoma.

J Natl Cancer Inst 2016 12 16;108(12). Epub 2016 Dec 16.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, AZ (LR), Department of Pathology and Laboratory Medicine, University of North Carolina Medical School, Chapel Hill, NC (YF), Center for Cancer Research, National Cancer Institute, Bethesda, MD (LMS), Department of Medicine, Weill Cornell Medical College, New York, NY (AM), Department of Pathology and Laboratory Medicine, British Columbia Cancer Agency, Vancouver, BC, Canada (RG), Clinical Cancer Research Unit, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada (MC), Coordinating Center for Clinical Trials, National Cancer Institute, Bethesda, MD (LB), Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE (KF), Department of Pathology and Laboratory Medicine, Cleveland Clinic Foundation, Cleveland, OH (ED), Department of Pathology, City of Hope Medical Center, Duarte, CA (JWCC), Biometrics Research Branch, National Cancer Institute, Bethesda, MD (LM), Department of Medicine, Weill Cornell Medicine, New York, NY (JPL), Department of Medicine, Oncology Division, Washington University, St. Louis, MO (BSK), Clinical Investigations Branch, Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD (RFL), Wilmot Cancer Center and Division of Hematology/Oncology, University of Rochester, Rochester, NY (JWF), Department of Radiology, Mount Sinai Medical Center New York, NY (LK).

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http://dx.doi.org/10.1093/jnci/djw250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080362PMC
December 2016

Roles for small noncoding RNAs in silencing of retrotransposons in the mammalian brain.

Proc Natl Acad Sci U S A 2016 Nov 24;113(45):12697-12702. Epub 2016 Oct 24.

Department of Neuroscience, Columbia University, New York, NY 10032;

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http://dx.doi.org/10.1073/pnas.1609287113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111663PMC
November 2016

Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region.

Immunity 2016 09 13;45(3):497-512. Epub 2016 Sep 13.

Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA; Department of Pharmacology, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033726PMC
September 2016

A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations.

Mol Cell 2016 08 28;63(4):711-719. Epub 2016 Jul 28.

Department of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics, Howard Hughes Medical Institute, University of Chicago, 929 East 57th Street, Chicago, IL 60637, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.06.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992443PMC
August 2016

The many layers of epigenetic dysfunction in B-cell lymphomas.

Curr Opin Hematol 2016 07;23(4):377-84

aWeill Cornell Cancer Center bDepartment of Physiology and Biophysics cDepartment of Medicine, Weill Cornell Medicine, New York City, New York, USA.

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http://pdfs.journals.lww.com/co-hematology/2016/07000/The_ma
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http://dx.doi.org/10.1097/MOH.0000000000000249DOI Listing
July 2016

Mutant IDH: a targetable driver of leukemic phenotypes linking metabolism, epigenetics and transcriptional regulation.

Epigenomics 2016 07 19;8(7):945-57. Epub 2016 Jul 19.

Division of Hematology/Medical Oncology, Department of Medicine, Weill Cornell Medicine, 413 East 69th Street, BRB 14th floor, New York, NY, USA.

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http://dx.doi.org/10.2217/epi-2016-0008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066133PMC
July 2016

miR-181a negatively regulates NF-κB signaling and affects activated B-cell-like diffuse large B-cell lymphoma pathogenesis.

Blood 2016 06 3;127(23):2856-66. Epub 2016 Mar 3.

Division of Hematology and Oncology, Department of Medicine, Department of Molecular and Cellular Pharmacology.

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http://dx.doi.org/10.1182/blood-2015-11-680462DOI Listing
June 2016

A clinical measure of DNA methylation predicts outcome in de novo acute myeloid leukemia.

JCI Insight 2016 Jun;1(9)

Department of Pathology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1172/jci.insight.87323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951094PMC
June 2016

DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia.

Cancer Discov 2016 05 25;6(5):501-15. Epub 2016 Mar 25.

Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio. Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

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http://dx.doi.org/10.1158/2159-8290.CD-16-0008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861898PMC
May 2016

Genetic and epigenetic heterogeneity in acute myeloid leukemia.

Curr Opin Genet Dev 2016 02 7;36:100-6. Epub 2016 May 7.

Department of Medicine and Meyer Cancer Center, Weill Cornell Medical College, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.gde.2016.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4903929PMC
February 2016

Integrin-specific hydrogels as adaptable tumor organoids for malignant B and T cells.

Biomaterials 2015 Dec 11;73:110-9. Epub 2015 Sep 11.

Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2015.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623826PMC
December 2015

Mechanisms of action of BCL6 during germinal center B cell development.

Sci China Life Sci 2015 Dec 14;58(12):1226-32. Epub 2015 Nov 14.

Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY, 10065, USA.

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http://dx.doi.org/10.1007/s11427-015-4919-zDOI Listing
December 2015

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma.

J Vis Exp 2015 Dec 28(106):e53215. Epub 2015 Dec 28.

Institute for Computational Biomedicine, Weill Cornell Medical College;

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http://dx.doi.org/10.3791/53215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780861PMC
December 2015

Transcriptome sequencing reveals thousands of novel long non-coding RNAs in B cell lymphoma.

Genome Med 2015 Nov 1;7:110. Epub 2015 Nov 1.

Institute for Computational Biomedicine, Weill Cornell Medical College, 1305 York Avenue, New York, NY, 10021, USA.

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http://dx.doi.org/10.1186/s13073-015-0230-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628784PMC
November 2015

Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis.

J Exp Med 2015 Oct 5;212(11):1819-32. Epub 2015 Oct 5.

Human Oncology and Pathogenesis Program, Leukemia Service, Department of Medicine, Department of Pathology, Molecular Cytology Core Facility, and Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065 Human Oncology and Pathogenesis Program, Leukemia Service, Department of Medicine, Department of Pathology, Molecular Cytology Core Facility, and Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065 Human Oncology and Pathogenesis Program, Leukemia Service, Department of Medicine, Department of Pathology, Molecular Cytology Core Facility, and Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065

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http://dx.doi.org/10.1084/jem.20151317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612085PMC
October 2015

DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID.

Cell Rep 2015 Sep 10;12(12):2086-98. Epub 2015 Sep 10.

Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY 10065, USA; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.08.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591215PMC
September 2015

VII. Are lymphomas driven by epigenetic lesions?

Hematol Oncol 2015 Jun;33 Suppl 1:42-5

Sandra and Edward Meyer Cancer Center, Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.1002/hon.2215DOI Listing
June 2015

The epigenetic basis of diffuse large B-cell lymphoma.

Semin Hematol 2015 Apr 19;52(2):86-96. Epub 2015 Jan 19.

Department of Medicine, Weill Cornell Medical College, New York, NY, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medical College, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1053/j.seminhematol.2015.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374125PMC
April 2015

BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms.

J Exp Med 2015 Apr 30;212(4):539-53. Epub 2015 Mar 30.

Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037

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http://jem.rupress.org/content/212/4/539.full.pdf
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http://www.jem.org/cgi/doi/10.1084/jem.20141380
Publisher Site
http://dx.doi.org/10.1084/jem.20141380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387288PMC
April 2015

Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia.

Cancer Cell 2015 Apr;27(4):502-15

Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518555PMC
April 2015

Epigenomic evolution in diffuse large B-cell lymphomas.

Nat Commun 2015 Apr 20;6:6921. Epub 2015 Apr 20.

1] Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medical College, 1300 York Avenue, New York, New York 10021, USA [2] Institute for Precision Medicine, Weill Cornell Medical College, 1300 York Avenue, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/ncomms7921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411286PMC
April 2015

Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia.

Nat Commun 2015 Mar 10;6:6471. Epub 2015 Mar 10.

1] Department of Laboratory Medicine, University of California San Francisco, San Francisco, California 94143, USA [2] Department of Haematology, University of Cambridge, Cambridge CB2 OAH, UK.

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http://dx.doi.org/10.1038/ncomms7471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366523PMC
March 2015

A roadmap for discovery and translation in lymphoma.

Blood 2015 Mar;125(13):2175-7

Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1182/blood-2015-01-623777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375113PMC
March 2015