Publications by authors named "Ardeshir Bayat"

100Publications

Assessment of transdermal delivery of topical compounds in skin scarring using a novel combined approach of Raman spectroscopy and HPLC.

Adv Wound Care (New Rochelle) 2020 Jun 4. Epub 2020 Jun 4.

University of Manchester, Plastic & Reconstructive Surgery Research, Manchester Institute of Biotechnology, Manchester, United Kingdom of Great Britain and Northern Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/wound.2020.1154DOI Listing
June 2020

A microbiome and metabolomic signature of phases of cutaneous healing identified by profiling sequential acute wounds of human skin: An exploratory study.

PLoS One 2020 27;15(2):e0229545. Epub 2020 Feb 27.

Plastic & Reconstructive Surgery Research, Division of Musculoskeletal & Dermatological Sciences, NIHR Manchester Biomedical Research Centre (BRC), University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0229545PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046225PMC
May 2020

Keloid scarring or disease: Unresolved quasi-neoplastic tendencies in the human skin.

Wound Repair Regen 2020 May 5;28(3):422-426. Epub 2020 Feb 5.

Plastic and Reconstructive Surgery Research, Centre for Dermatology Research, NIHR Manchester Biomedical Research Centre, University of Manchester, Manchester, England, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/wrr.12793DOI Listing
May 2020

and Models for Functional Testing of Therapeutic Anti-scarring Drug Targets in Keloids.

Adv Wound Care (New Rochelle) 2019 Dec 6;8(12):655-670. Epub 2019 Nov 6.

Hair and Skin Research Laboratory, Division of Dermatology, Department of Medicine, Faculty of Health Sciences and Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/wound.2019.1040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904937PMC
December 2019

Functional Testing of a Skin Topical Formulation : Objective and Quantitative Evaluation in Human Skin Scarring Using a Double-Blind Volunteer Study with Sequential Punch Biopsies.

Adv Wound Care (New Rochelle) 2019 May 3;8(5):208-219. Epub 2019 May 3.

Plastic and Reconstructive Surgery Research, Division of Musuloskeletal and Dermatological Sciences, Centre for Dermatology Research, NIHR Manchester BRC, University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/wound.2018.0864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855292PMC
May 2019

Understanding Keloid Pathobiology From a Quasi-Neoplastic Perspective: Less of a Scar and More of a Chronic Inflammatory Disease With Cancer-Like Tendencies.

Front Immunol 2019 7;10:1810. Epub 2019 Aug 7.

Plastic and Reconstructive Surgery Research, Centre for Dermatology Research, NIHR Manchester Biomedical Research Centre, University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2019.01810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692789PMC
August 2019

Development of Bioinspired Gelatin and Gelatin/Chitosan Bilayer Hydrofilms for Wound Healing.

Pharmaceutics 2019 Jul 4;11(7). Epub 2019 Jul 4.

NanoBioCel Group, Laboratory of Pharmaceutics, School of Pharmacy, University of the Basque Country (UPV/EHU), Paseo de la Universidad 7, 01006 Vitoria-Gasteiz, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/pharmaceutics11070314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680716PMC
July 2019

Microarchitectural analysis of decellularised unscarred and scarred dermis provides insight into the organisation and ultrastructure of the human skin with implications for future dermal substitute scaffold design.

J Tissue Eng 2019 Jan-Dec;10:2041731419843710. Epub 2019 Jun 18.

Plastic and Reconstructive Surgery Research, Division of Musculoskeletal & Dermatological Sciences, NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2041731419843710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582285PMC
June 2019

A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin.

J Invest Dermatol 2019 08 26;139(8):1680-1690.e16. Epub 2019 Feb 26.

Plastic and Reconstructive Surgery Research, University of Manchester, Manchester, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jid.2019.01.030DOI Listing
August 2019

Multi-dimensional models for functional testing of keloid scars: In silico, in vitro, organoid, organotypic, ex vivo organ culture, and in vivo models.

Wound Repair Regen 2019 07 25;27(4):298-308. Epub 2019 Mar 25.

Hair and Skin Research Laboratory, Division of Dermatology, Department of Medicine, Faculty of Health Sciences and Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/wrr.12705DOI Listing
July 2019

Electrical stimulation disrupts biofilms in a human wound model and reveals the potential for monitoring treatment response with volatile biomarkers.

Wound Repair Regen 2019 01 21;27(1):5-18. Epub 2018 Nov 21.

Plastic & Reconstructive Surgery Research, Division of Musculoskeletal & Dermatological Sciences, School of Biological Sciences, University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/wrr.12679
Publisher Site
http://dx.doi.org/10.1111/wrr.12679DOI Listing
January 2019

Validation of biofilm formation on human skin wound models and demonstration of clinically translatable bacteria-specific volatile signatures.

Sci Rep 2018 06 21;8(1):9431. Epub 2018 Jun 21.

Plastic & Reconstructive Surgery Research, Division of Musculoskeletal & Dermatological Sciences, School of Biological Sciences, University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-27504-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013498PMC
June 2018

Photobiomodulation of a flowable matrix in a human skin ex vivo model demonstrates energy-based enhancement of engraftment integration and remodeling.

J Biophotonics 2018 09 29;11(9):e201800077. Epub 2018 May 29.

School of Biological Sciences and Health/Division of Musculoskeletal and Dermatological Sciences, University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jbio.201800077DOI Listing
September 2018

Volatile organic compound detection as a potential means of diagnosing cutaneous wound infections.

Wound Repair Regen 2017 08 31;25(4):574-590. Epub 2017 Aug 31.

Plastic and Reconstructive Surgery Research, Institute of Inflammation and Repair, Centre for Dermatological Research, University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/wrr.12563DOI Listing
August 2017

Therapeutic targets in the management of striae distensae: A systematic review.

J Am Acad Dermatol 2017 Sep 24;77(3):559-568.e18. Epub 2017 May 24.

Centre for Dermatological Research, University of Manchester, Manchester, United Kingdom. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaad.2017.02.048DOI Listing
September 2017

Cutaneous wound biofilm and the potential for electrical stimulation in management of the microbiome.

Future Microbiol 2017 03 3;12:337-357. Epub 2017 Mar 3.

Plastic & Reconstructive Surgery Research, Centre for Dermatological Research, University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/fmb-2016-0204DOI Listing
March 2017

Non-animal models of wound healing in cutaneous repair: In silico, in vitro, ex vivo, and in vivo models of wounds and scars in human skin.

Wound Repair Regen 2017 04 20;25(2):164-176. Epub 2017 Feb 20.

Plastic and Reconstructive Surgery Research, Centre for Dermatology Research, University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/wrr.12513DOI Listing
April 2017

A Role for Neuregulin-1 in Promoting Keloid Fibroblast Migration via ErbB2-mediated Signaling.

Acta Derm Venereol 2017 Jun;97(6):675-684

Plastic and Reconstructive Surgery Research, Stopford Building, Manchester M13 9PT , United Kingdom.

View Article

Download full-text PDF

Source
https://www.medicaljournals.se/acta/content/abstract/10.2340
Publisher Site
http://dx.doi.org/10.2340/00015555-2587DOI Listing
June 2017

Enhanced Neurogenic Biomarker Expression and Reinnervation in Human Acute Skin Wounds Treated by Electrical Stimulation.

J Invest Dermatol 2017 03 14;137(3):737-747. Epub 2016 Nov 14.

Plastic Surgery Research Group, Dermatology Research Centre, Institute of Inflammation & Repair, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0022202X163264
Publisher Site
http://dx.doi.org/10.1016/j.jid.2016.09.038DOI Listing
March 2017

Identification of a Potential Molecular Diagnostic Biomarker in Keloid Disease: Syndecan-1 (CD138) Is Overexpressed in Keloid Scar Tissue.

J Invest Dermatol 2016 11 14;136(11):2319-2323. Epub 2016 Jul 14.

Plastic and Reconstructive Surgery Research, University of Manchester, Manchester, UK; The Dermatology Centre, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jid.2016.06.623DOI Listing
November 2016

The efficacy of electrical stimulation in lower extremity cutaneous wound healing: A systematic review.

Exp Dermatol 2017 02;26(2):171-178

Plastic and Reconstructive Surgery Research, Centre for Dermatological Research, Institute of Inflammation and Repair, University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/exd.13179DOI Listing
February 2017

Fabrication and modelling of fractal, biomimetic, micro and nano-topographical surfaces.

Bioinspir Biomim 2016 07 25;11(4):046009. Epub 2016 Jul 25.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK. School of Computer Science, Centre for Mesoscience and Nanotechnology, The University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1088/1748-3190/11/4/046009DOI Listing
July 2016

Whole genome microarray data of chronic wound debridement prior to application of dermal skin substitutes.

Wound Repair Regen 2016 Sep 2;24(5):870-875. Epub 2016 Aug 2.

Plastic and Reconstructive Surgery Research, Centre for Dermatological Research, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/wrr.12460
Publisher Site
http://dx.doi.org/10.1111/wrr.12460DOI Listing
September 2016

The efficacy of electrical stimulation in experimentally induced cutaneous wounds in animals.

Vet Dermatol 2016 Aug 18;27(4):235-e57. Epub 2016 May 18.

Plastic and Reconstructive Surgery Research, Centre for Dermatological Research, Institute of Inflammation and Repair, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/vde.12328DOI Listing
August 2016

Non-invasive objective devices for monitoring the inflammatory, proliferative and remodelling phases of cutaneous wound healing and skin scarring.

Exp Dermatol 2016 08 15;25(8):579-85. Epub 2016 Jun 15.

Plastic and Reconstructive Surgery Research, Institute of Inflammation and Repair, University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/exd.13027DOI Listing
August 2016

The Aldo-Keto Reductase AKR1B10 Is Up-Regulated in Keloid Epidermis, Implicating Retinoic Acid Pathway Dysregulation in the Pathogenesis of Keloid Disease.

J Invest Dermatol 2016 07 26;136(7):1500-1512. Epub 2016 Mar 26.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, Manchester, UK; Centre for Dermatology Research, Institute of Inflammation and Repair, University of Manchester, Manchester, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jid.2016.03.022DOI Listing
July 2016

IL-33-Dependent Group 2 Innate Lymphoid Cells Promote Cutaneous Wound Healing.

J Invest Dermatol 2016 Feb;136(2):487-496

Department of Clinical Studies-Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/JID.2015.406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731037PMC
February 2016

In vitro and ex vivo analysis of hyaluronan supplementation of Integra® dermal template on human dermal fibroblasts and keratinocytes.

J Appl Biomater Funct Mater 2016 Apr 6;14(1):e9-18. Epub 2016 Apr 6.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, Manchester - UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5301/jabfm.5000259DOI Listing
April 2016

The Role of Neuromediators and Innervation in Cutaneous Wound Healing.

Acta Derm Venereol 2016 Jun;96(5):587-94

Plastic and Reconstructive Surgery Research, Centre for Dermatological Research,, Institute of Inflammation and Repair, University of Manchester, M13 9PT Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2340/00015555-2321DOI Listing
June 2016

Chemokines in Wound Healing and as Potential Therapeutic Targets for Reducing Cutaneous Scarring.

Adv Wound Care (New Rochelle) 2015 Nov;4(11):687-703

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology (MIB), The University of Manchester , Manchester, United Kingdom .

View Article

Download full-text PDF

Source
http://www.liebertpub.com/doi/10.1089/wound.2014.0568
Publisher Site
http://dx.doi.org/10.1089/wound.2014.0568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620529PMC
November 2015

Ex vivo evaluation of acellular and cellular collagen-glycosaminoglycan flowable matrices.

Biomed Mater 2015 Jul 16;10(4):041001. Epub 2015 Jul 16.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, 131 Princess St, University of Manchester, Manchester, UK. School of Chemical Engineering and Analytical Science, Manchester Institute of Biotechnology, 131 Princess St, University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1088/1748-6041/10/4/041001DOI Listing
July 2015

Noninvasive device readouts validated by immunohistochemical analysis enable objective quantitative assessment of acute wound healing in human skin.

Wound Repair Regen 2015 Nov-Dec;23(6):901-14. Epub 2015 Nov 4.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/wrr.12344DOI Listing
October 2016

Optimization of an ex vivo wound healing model in the adult human skin: Functional evaluation using photodynamic therapy.

Wound Repair Regen 2015 Sep 8;23(5):685-702. Epub 2015 Sep 8.

Bioengineering Group, School of Materials.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/wrr.12325DOI Listing
September 2015

Skin substitute-assisted repair shows reduced dermal fibrosis in acute human wounds validated simultaneously by histology and optical coherence tomography.

Wound Repair Regen 2015 Jul-Aug;23(4):483-94. Epub 2015 Jul 31.

Plastic and Reconstructive Surgery Research, Institute of Inflammation and Repair, The University of Manchester.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/wrr.12308DOI Listing
June 2016

Angiogenesis is induced and wound size is reduced by electrical stimulation in an acute wound healing model in human skin.

PLoS One 2015 30;10(4):e0124502. Epub 2015 Apr 30.

Plastic & Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom; University Hospital of South Manchester NHS Foundation Trust, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom; Centre for Dermatology Research, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0124502PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415761PMC
December 2015

Enhanced Contraction of a Normal Breast-Derived Fibroblast-Populated Three-Dimensional Collagen Lattice via Contracted Capsule Fibroblast-Derived Paracrine Factors: Functional Significance in Capsular Contracture Formation.

Plast Reconstr Surg 2015 May;135(5):1413-29

Manchester, United Kingdom From Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester; and the Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, University of Manchester, Manchester Academic Health Science Center.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PRS.0000000000001177DOI Listing
May 2015

Ex vivo evaluation of the effect of photodynamic therapy on skin scars and striae distensae.

Photodermatol Photoimmunol Photomed 2015 Sep 1;31(5):239-51. Epub 2015 Jun 1.

Bioengineering Group, School of Materials, The University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/phpp.12180DOI Listing
September 2015

Development and functional evaluation of biomimetic silicone surfaces with hierarchical micro/nano-topographical features demonstrates favourable in vitro foreign body response of breast-derived fibroblasts.

Biomaterials 2015 Jun 21;52:88-102. Epub 2015 Feb 21.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, Manchester, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biomaterials.2015.02.003DOI Listing
June 2015

Acute cutaneous wounds treated with human decellularised dermis show enhanced angiogenesis during healing.

PLoS One 2015 20;10(1):e0113209. Epub 2015 Jan 20.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology (MIB), The University of Manchester, Manchester, Lancashire, United Kingdom; Centre for Dermatology, Institute of Inflammation and Repair, Faculty of Medicine and Human Sciences, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0113209PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300088PMC
September 2015

Electrical stimulation enhances epidermal proliferation in human cutaneous wounds by modulating p53-SIVA1 interaction.

J Invest Dermatol 2015 Apr 28;135(4):1166-1174. Epub 2014 Nov 28.

Plastic and Reconstructive Surgery Research, Institute of Inflammation and Repair, Manchester Institute of Biotechnology, School of Medical and Human Sciences, University of Manchester, Manchester, UK; Centre for Dermatology, Institute of Inflammation and Repair, University of Manchester, Manchester, UK; Manchester Academic Health Science Centre, South Manchester University Hospital Foundation Trust, Wythenshawe Hospital, Manchester, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/jid.2014.502DOI Listing
April 2015

Electrospun silk fibroin fiber diameter influences in vitro dermal fibroblast behavior and promotes healing of ex vivo wound models.

J Tissue Eng 2014 18;5:2041731414551661. Epub 2014 Sep 18.

Plastic & Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2041731414551661DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221927PMC
November 2014

Identification of biomarkers involved in differential profiling of hypertrophic and keloid scars versus normal skin.

Arch Dermatol Res 2015 Mar 17;307(2):115-33. Epub 2014 Oct 17.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology (MIB), University of Manchester, 131 Princess Road, Manchester, M1 7ND, UK.

View Article

Download full-text PDF

Source
http://search.proquest.com/openview/9869438a0c3058e8e30e60ae
Web Search
http://link.springer.com/10.1007/s00403-014-1512-4
Publisher Site
http://dx.doi.org/10.1007/s00403-014-1512-4DOI Listing
March 2015

Physico-chemical characteristics of coated silicone textured versus smooth breast implants differentially influence breast-derived fibroblast morphology and behaviour.

J Mech Behav Biomed Mater 2014 Dec 3;40:140-155. Epub 2014 Sep 3.

Plastic & Reconstructive Surgery Research, Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK; Faculty of Medical and Human Sciences, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmbbm.2014.08.018DOI Listing
December 2014

Skin equivalent tensional force alters keloid fibroblast behavior and phenotype.

Wound Repair Regen 2014 Sep-Oct;22(5):557-68

Plastic & Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom; Bioengineering Group, School of Materials, University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/wrr.12215DOI Listing
June 2015

First identification of resident and circulating fibrocytes in Dupuytren's disease shown to be inhibited by serum amyloid P and Xiapex.

PLoS One 2014 16;9(6):e99967. Epub 2014 Jun 16.

Plastic & Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom; Department of Plastic and Reconstructive Surgery, University Hospital South Manchester NHS Foundation Trust, Wythenshawe Hospital, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0099967PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059720PMC
January 2015

Regenerative healing, scar-free healing and scar formation across the species: current concepts and future perspectives.

Exp Dermatol 2014 Sep 21;23(9):615-9. Epub 2014 Jul 21.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, Institute of Inflammation and Repair, University of Manchester, Manchester, UK; University Hospital of South Manchester NHS Foundation Trust, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/exd.12457DOI Listing
September 2014

New insights on keloids, hypertrophic scars, and striae.

Dermatol Clin 2014 Apr;32(2):193-209

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK; Plastic and Reconstructive Surgery Research, Faculty of Medical and Human Sciences, Institute of Inflammation and Repair, University Hospital of South Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.det.2013.11.002DOI Listing
April 2014

Rheology and electrospinning of regenerated bombyx mori silk fibroin aqueous solutions.

Biomacromolecules 2014 Apr 24;15(4):1288-98. Epub 2014 Mar 24.

Manchester Institute of Biotechnology and ‡School of Chemical Engineering and Analytical Science, University of Manchester , Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bm4018319DOI Listing
April 2014

Interactions of the Extracellular Matrix and Progenitor Cells in Cutaneous Wound Healing.

Adv Wound Care (New Rochelle) 2013 Jul;2(6):261-272

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester , Manchester, United Kingdom . ; Department of Plastic and Reconstructive Surgery, Wythenshawe Hospital, University Hospital South Manchester NHS Foundation Trust, University of Manchester , Manchester, United Kingdom . ; Institute of Inflammation and Repair, Manchester Academic Health Science Center, Wythenshawe Hospital, University Hospital South Manchester NHS Foundation Trust, University of Manchester , Manchester, United Kingdom .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/wound.2012.0417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751325PMC
July 2013

Electrical Stimulation and Cutaneous Wound Healing: A Review of Clinical Evidence.

Healthcare (Basel) 2014 Oct 27;2(4):445-67. Epub 2014 Oct 27.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, Manchester M1 7DN, UK.

View Article

Download full-text PDF

Source
http://www.mdpi.com/2227-9032/2/4/445
Publisher Site
http://dx.doi.org/10.3390/healthcare2040445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934569PMC
October 2014

Site-specific keloid fibroblasts alter the behaviour of normal skin and normal scar fibroblasts through paracrine signalling.

PLoS One 2013 9;8(12):e75600. Epub 2013 Dec 9.

Plastic & Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, United Kingdom ; Institute of Inflammation & Repair, University of Manchester, Manchester, United Kingdom ; Department of Plastic and Reconstructive Surgery, University Hospital South Manchester Foundation Trust, Wythenshawe Hospital, Manchester, United Kingdom ; The University of Manchester, Manchester Academic Health Science Centre, University Hospital South Manchester Foundation Trust, Wythenshawe Hospital, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0075600PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857170PMC
September 2014

Single-stage application of a novel decellularized dermis for treatment-resistant lower limb ulcers: positive outcomes assessed by SIAscopy, laser perfusion, and 3D imaging, with sequential timed histological analysis.

Wound Repair Regen 2013 Nov-Dec;21(6):813-22. Epub 2013 Oct 17.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom; Wythenshawe Hospital, University Hospital of South Manchester NHS Foundation Trust, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/wrr.12113DOI Listing
November 2014

Current understanding of molecular and cellular mechanisms in fibroplasia and angiogenesis during acute wound healing.

J Dermatol Sci 2013 Dec 30;72(3):206-17. Epub 2013 Jul 30.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, UK; The University of Manchester, Manchester Academic Health Science Centre, University Hospital South Manchester Foundation Trust, Wythenshawe Hospital, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jdermsci.2013.07.008DOI Listing
December 2013

Identification of molecular phenotypic descriptors of breast capsular contracture formation using informatics analysis of the whole genome transcriptome.

Wound Repair Regen 2013 Sep-Oct;21(5):762-9. Epub 2013 Aug 13.

Plastic & Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/wrr.12077DOI Listing
May 2014

Significant reduction of symptoms of scarring with electrical stimulation: evaluated with subjective and objective assessment tools in a prospective noncontrolled case series.

Wounds 2013 Aug;25(8):212-24

Manchester Institute of Biotechnology, University of Manchester, Manchester, UK and University Hospital of South Manchester NHS Foundation Trust, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK;

View Article

Download full-text PDF

Source
http://www.medxhealth.com/cmsAssets/docs/pdfs/Clinical-trial
Web Search
August 2013

Ex vivo evaluation of antifibrotic compounds in skin scarring: EGCG and silencing of PAI-1 independently inhibit growth and induce keloid shrinkage.

Lab Invest 2013 Aug 8;93(8):946-60. Epub 2013 Jul 8.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology (MIB), University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/labinvest.2013.82DOI Listing
August 2013

A double-blind controlled clinical trial assessing the effect of topical gels on striae distensae (stretch marks): a non-invasive imaging, morphological and immunohistochemical study.

Arch Dermatol Res 2013 Sep 12;305(7):603-17. Epub 2013 Apr 12.

Plastic and Reconstructive Surgery Research (PRSR), Manchester Institute of Biotechnology (MIB), University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-013-1336-7DOI Listing
September 2013

Characterisation of breast implant surfaces and correlation with fibroblast adhesion.

J Mech Behav Biomed Mater 2013 May 27;21:133-48. Epub 2013 Feb 27.

Bioengineering Group, School of Mechanical, Aerospace and Civil Engineering, The University of Manchester, Manchester M13 9PL, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmbbm.2013.02.005DOI Listing
May 2013

Designing implant surface topography for improved biocompatibility.

Expert Rev Med Devices 2013 Mar;10(2):257-67

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/erd.12.82DOI Listing
March 2013

Identification of steroid sensitive responders versus non-responders in the treatment of keloid disease.

Arch Dermatol Res 2013 Jul 12;305(5):423-32. Epub 2013 Mar 12.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7ND, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-013-1328-7DOI Listing
July 2013

The role of skin substitutes in the management of chronic cutaneous wounds.

Wound Repair Regen 2013 Mar-Apr;21(2):194-210. Epub 2013 Feb 25.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology (MIB), The University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/wrr.12029DOI Listing
October 2013

Up-regulation of tension-related proteins in keloids: knockdown of Hsp27, α2β1-integrin, and PAI-2 shows convincing reduction of extracellular matrix production.

Plast Reconstr Surg 2013 Feb;131(2):158e-173e

Plastic and Reconstructive Surgery Research, School of Translational Medicine, Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PRS.0b013e3182789b2bDOI Listing
February 2013

Potent dual inhibitors of TORC1 and TORC2 complexes (KU-0063794 and KU-0068650) demonstrate in vitro and ex vivo anti-keloid scar activity.

J Invest Dermatol 2013 May 10;133(5):1340-50. Epub 2013 Jan 10.

Plastic & Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/jid.2012.483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631609PMC
May 2013

Superior effect of combination vs. single steroid therapy in keloid disease: a comparative in vitro analysis of glucocorticoids.

Wound Repair Regen 2013 Jan-Feb;21(1):88-102. Epub 2012 Nov 5.

Plastic & Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1524-475X.2012.00862.xDOI Listing
July 2013

Photodynamic therapy: an innovative approach to the treatment of keloid disease evaluated using subjective and objective non-invasive tools.

Arch Dermatol Res 2013 Apr 2;305(3):205-14. Epub 2012 Nov 2.

Faculty of Medical and Human Sciences, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, University Hospital of South Manchester NHS Foundation Trust, University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-012-1295-4DOI Listing
April 2013

Identification of biomarkers in sequential biopsies of patients with chronic wounds receiving simultaneous acute wounds: a genetic, histological, and noninvasive imaging study.

Wound Repair Regen 2012 Sep-Oct;20(5):757-69

Plastic and Reconstructive Surgery Research, Manchester Interdisciplinary Biocentre, University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1524-475X.2012.00832.xDOI Listing
February 2013

Notch signaling pathway in keloid disease: enhanced fibroblast activity in a Jagged-1 peptide-dependent manner in lesional vs. extralesional fibroblasts.

Wound Repair Regen 2012 Sep-Oct;20(5):688-706

Plastic & Reconstructive Surgery Research, Manchester Interdisciplinary Biocentre, University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1524-475X.2012.00823.xDOI Listing
February 2013

Keloid disease can be inhibited by antagonizing excessive mTOR signaling with a novel dual TORC1/2 inhibitor.

Am J Pathol 2012 Nov 11;181(5):1642-58. Epub 2012 Sep 11.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2012.08.006DOI Listing
November 2012

Understanding Dupuytren's Disease Using Systems Biology: A Move Away from Reductionism.

Front Physiol 2012 9;3:316. Epub 2012 Aug 9.

Manchester Centre for Integrative Systems Biology, University of Manchester Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fphys.2012.00316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429086PMC
October 2012

Differential cytotoxic response in keloid fibroblasts exposed to photodynamic therapy is dependent on photosensitiser precursor, fluence and location of fibroblasts within the lesion.

Arch Dermatol Res 2012 Sep 4;304(7):549-62. Epub 2012 Aug 4.

Plastic and Reconstructive Surgery Research, School of Translational Medicine, Manchester Institute of Biotechnology (MIB), The University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-012-1264-yDOI Listing
September 2012

Perturbation of cell cycle expression in keloid fibroblast.

Skinmed 2012 May-Jun;10(3):152-9

Quantitative Molecular Medicine Group, School of Cancer & Enabling Sciences, Manchester Interdisciplinary Biocentre, The University of Manchester, 131 Princess Street, Manchester M1 7DN, United Kingdom.

View Article

Download full-text PDF

Source
July 2012

Dupuytren's disease metabolite analyses reveals alterations following initial short-term fibroblast culturing.

Mol Biosyst 2012 Sep 6;8(9):2274-88. Epub 2012 Jul 6.

Doctoral Training Centre ISBML, The Manchester Centre for Integrative Systems Biology, Manchester Institute of Biotechnology, University of Manchester, Manchester, M1 7DN, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c2mb25173fDOI Listing
September 2012

Cellular senescence as a possible mechanism for halting progression of keloid lesions.

Genes Cancer 2011 Nov;2(11):1061-6

Department of Surgery, Thyroid Cancer Research Laboratory, Endocrine Surgery Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1947601912440877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379565PMC
November 2011

Extensive self-harm scarring: successful treatment with simultaneous use of a single layer skin substitute and split-thickness skin graft.

Eplasty 2012 21;12:e23. Epub 2012 May 21.

University Hospital of South Manchester NHS Foundation Trust, Faculty of Medical and Human Sciences, University of Manchester, Manchester Academic Health Science Centre; and Plastic and Reconstructive Surgery Research, School of Translational Medicine, Manchester Interdisciplinary Biocentre, University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359068PMC
August 2012

Long-term organ culture of keloid disease tissue.

Exp Dermatol 2012 May;21(5):376-81

Plastic and Reconstructive Surgery Research, Manchester Interdisciplinary Biocentre, University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1600-0625.2012.01476.xDOI Listing
May 2012

In vitro study of novel collagenase (XIAFLEX®) on Dupuytren's disease fibroblasts displays unique drug related properties.

PLoS One 2012 24;7(2):e31430. Epub 2012 Feb 24.

Plastic and Reconstructive Surgery Research, School of Translational Medicine, Manchester Interdisciplinary Biocentre, University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0031430PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286458PMC
August 2012

DNA copy number variations at chromosome 7p14.1 and chromosome 14q11.2 are associated with dupuytren's disease: potential role for MMP and Wnt signaling pathway.

Plast Reconstr Surg 2012 Apr;129(4):921-32

Plastic and Reconstructive Surgery Research, Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess Street, Manchester M1 7DN, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PRS.0b013e3182442343DOI Listing
April 2012

Acceleration of cutaneous healing by electrical stimulation: degenerate electrical waveform down-regulates inflammation, up-regulates angiogenesis and advances remodeling in temporal punch biopsies in a human volunteer study.

Wound Repair Regen 2011 Nov 19;19(6):693-708. Epub 2011 Oct 19.

Plastic & Reconstructive Surgery Research, School of Translational Medicine, Manchester Interdisciplinary Biocentre, The University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1524-475X.2011.00736.xDOI Listing
November 2011

Connective tissue diseases: Unpicking Dupruyten disease etiology-is Wnt the way?

Authors:
Ardeshir Bayat

Nat Rev Rheumatol 2011 Nov 15;8(1):5-6. Epub 2011 Nov 15.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrrheum.2011.172DOI Listing
November 2011

Comparative genomic hybridisation analysis of keloid tissue in Caucasians suggests possible involvement of HLA-DRB5 in disease pathogenesis.

Arch Dermatol Res 2012 Apr 28;304(3):241-9. Epub 2011 Oct 28.

Plastic and Reconstructive Surgery Research, School of Translational Medicine, The Manchester Interdisciplinary Biocentre (MIB), University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-011-1182-4DOI Listing
April 2012

Addition of novel degenerate electrical waveform stimulation with photodynamic therapy significantly enhances its cytotoxic effect in keloid fibroblasts: first report of a potential combination therapy.

J Dermatol Sci 2011 Dec 17;64(3):174-84. Epub 2011 Sep 17.

Plastic & Reconstructive Surgery Research, School of Translational Medicine, Manchester Interdisciplinary Biocentre (MIB), The University of Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jdermsci.2011.08.012DOI Listing
December 2011

Dupuytren's: a systems biology disease.

Arthritis Res Ther 2011 12;13(5):238. Epub 2011 Sep 12.

Manchester Centre for Integrative Systems Biology, University of Manchester, Manchester, M1 7DN, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/ar3438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308066PMC
December 2012

Role of the HLA System in the Pathogenesis of Dupuytren's Disease.

Hand (N Y) 2010 Sep 9;5(3):241-50. Epub 2010 Feb 9.

University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11552-009-9255-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920393PMC
September 2010

Degenerate wave and capacitive coupling increase human MSC invasion and proliferation while reducing cytotoxicity in an in vitro wound healing model.

PLoS One 2011 16;6(8):e23404. Epub 2011 Aug 16.

Plastic & Reconstructive Surgery Research, School of Translational Medicine, Manchester Interdisciplinary Biocentre, University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0023404PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156742PMC
February 2012

Identification of mesenchymal stem cells in perinodular fat and skin in Dupuytren's disease: a potential source of myofibroblasts with implications for pathogenesis and therapy.

Stem Cells Dev 2012 Mar 19;21(4):609-22. Epub 2011 Jul 19.

Plastic and Reconstructive Surgery Research, Manchester Interdisciplinary Biocentre, University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/scd.2011.0140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280606PMC
March 2012

A clinical characterization of familial keloid disease in unique African tribes reveals distinct keloid phenotypes.

Plast Reconstr Surg 2011 Feb;127(2):689-702

Plastic and Reconstructive Surgery Research, University of Manchester, Manchester, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PRS.0b013e3181fed645DOI Listing
February 2011

Breast implant surface development: perspectives on development and manufacture.

Aesthet Surg J 2011 Jan;31(1):56-67

Manchester Interdisciplinary Biocentre, School of Translational Medicine, University of Manchester, 131 Princess Street, Manchester, UK.

View Article

Download full-text PDF

Source
http://asj.oxfordjournals.org/content/asj/31/1/56.full.pdf
Web Search
http://asj.oxfordjournals.org/cgi/doi/10.1177/1090820X103909
Publisher Site
http://dx.doi.org/10.1177/1090820X10390921DOI Listing
January 2011

Hyaluronan, TSG-6, and inter-α-inhibitor in periprosthetic breast capsules: reduced levels of free hyaluronan and TSG-6 expression in contracted capsules.

Aesthet Surg J 2011 Jan;31(1):47-55

National Institute for Health Research and Plastic & Reconstructive Surgery Research, University of Manchester, 131 Princess Street, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1090820X10391778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428900PMC
January 2011

Positive response of a recurrent keloid scar to topical methyl aminolevulinate-photodynamic therapy.

Photodermatol Photoimmunol Photomed 2010 Dec;26(6):330-2

Photobiology Unit, Dermatology Centre, Salford Royal NHS Foundation Hospital, Stott Lane, Salford, Manchester M68HD, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1600-0781.2010.00539.xDOI Listing
December 2010

The emerging role of Clostridium histolyticum collagenase in the treatment of Dupuytren disease.

Ther Clin Risk Manag 2010 Nov 4;6:557-72. Epub 2010 Nov 4.

Plastic and Reconstructive Surgery Research, School of Translational Medicine, University of Manchester, Manchester Interdisciplinary Biocentre, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/TCRM.S8591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988615PMC
November 2010