Publications by authors named "Arden Moscati"

23Publications

Inherited causes of clonal haematopoiesis in 97,691 whole genomes.

Authors:
Alexander G Bick Joshua S Weinstock Satish K Nandakumar Charles P Fulco Erik L Bao Seyedeh M Zekavat Mindy D Szeto Xiaotian Liao Matthew J Leventhal Joseph Nasser Kyle Chang Cecelia Laurie Bala Bharathi Burugula Christopher J Gibson Amy E Lin Margaret A Taub Francois Aguet Kristin Ardlie Braxton D Mitchell Kathleen C Barnes Arden Moscati Myriam Fornage Susan Redline Bruce M Psaty Edwin K Silverman Scott T Weiss Nicholette D Palmer Ramachandran S Vasan Esteban G Burchard Sharon L R Kardia Jiang He Robert C Kaplan Nicholas L Smith Donna K Arnett David A Schwartz Adolfo Correa Mariza de Andrade Xiuqing Guo Barbara A Konkle Brian Custer Juan M Peralta Hongsheng Gui Deborah A Meyers Stephen T McGarvey Ida Yii-Der Chen M Benjamin Shoemaker Patricia A Peyser Jai G Broome Stephanie M Gogarten Fei Fei Wang Quenna Wong May E Montasser Michelle Daya Eimear E Kenny Kari E North Lenore J Launer Brian E Cade Joshua C Bis Michael H Cho Jessica Lasky-Su Donald W Bowden L Adrienne Cupples Angel C Y Mak Lewis C Becker Jennifer A Smith Tanika N Kelly Stella Aslibekyan Susan R Heckbert Hemant K Tiwari Ivana V Yang John A Heit Steven A Lubitz Jill M Johnsen Joanne E Curran Sally E Wenzel Daniel E Weeks Dabeeru C Rao Dawood Darbar Jee-Young Moon Russell P Tracy Erin J Buth Nicholas Rafaels Ruth J F Loos Peter Durda Yongmei Liu Lifang Hou Jiwon Lee Priyadarshini Kachroo Barry I Freedman Daniel Levy Lawrence F Bielak James E Hixson James S Floyd Eric A Whitsel Patrick T Ellinor Marguerite R Irvin Tasha E Fingerlin Laura M Raffield Sebastian M Armasu Marsha M Wheeler Ester C Sabino John Blangero L Keoki Williams Bruce D Levy Wayne Huey-Herng Sheu Dan M Roden Eric Boerwinkle JoAnn E Manson Rasika A Mathias Pinkal Desai Kent D Taylor Andrew D Johnson Paul L Auer Charles Kooperberg Cathy C Laurie Thomas W Blackwell Albert V Smith Hongyu Zhao Ethan Lange Leslie Lange Stephen S Rich Jerome I Rotter James G Wilson Paul Scheet Jacob O Kitzman Eric S Lander Jesse M Engreitz Benjamin L Ebert Alexander P Reiner Siddhartha Jaiswal Gonçalo Abecasis Vijay G Sankaran Sekar Kathiresan Pradeep Natarajan

Nature 2020 Oct 14. Epub 2020 Oct 14.

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41586-020-2819-2DOI Listing
October 2020

A genotype-first approach to exploring Mendelian cardiovascular traits with clear external manifestations.

Genet Med 2020 Sep 29. Epub 2020 Sep 29.

Mindich Child Health and Development Institute, Icahn School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1038/s41436-020-00973-2DOI Listing
September 2020

The Polygenic and Monogenic Basis of Blood Traits and Diseases.

Authors:
Dragana Vuckovic Erik L Bao Parsa Akbari Caleb A Lareau Abdou Mousas Tao Jiang Ming-Huei Chen Laura M Raffield Manuel Tardaguila Jennifer E Huffman Scott C Ritchie Karyn Megy Hannes Ponstingl Christopher J Penkett Patrick K Albers Emilie M Wigdor Saori Sakaue Arden Moscati Regina Manansala Ken Sin Lo Huijun Qian Masato Akiyama Traci M Bartz Yoav Ben-Shlomo Andrew Beswick Jette Bork-Jensen Erwin P Bottinger Jennifer A Brody Frank J A van Rooij Kumaraswamy N Chitrala Peter W F Wilson Hélène Choquet John Danesh Emanuele Di Angelantonio Niki Dimou Jingzhong Ding Paul Elliott Tõnu Esko Michele K Evans Stephan B Felix James S Floyd Linda Broer Niels Grarup Michael H Guo Qi Guo Andreas Greinacher Jeff Haessler Torben Hansen Joanna M M Howson Wei Huang Eric Jorgenson Tim Kacprowski Mika Kähönen Yoichiro Kamatani Masahiro Kanai Savita Karthikeyan Fotios Koskeridis Leslie A Lange Terho Lehtimäki Allan Linneberg Yongmei Liu Leo-Pekka Lyytikäinen Ani Manichaikul Koichi Matsuda Karen L Mohlke Nina Mononen Yoshinori Murakami Girish N Nadkarni Kjell Nikus Nathan Pankratz Oluf Pedersen Michael Preuss Bruce M Psaty Olli T Raitakari Stephen S Rich Benjamin A T Rodriguez Jonathan D Rosen Jerome I Rotter Petra Schubert Cassandra N Spracklen Praveen Surendran Hua Tang Jean-Claude Tardif Mohsen Ghanbari Uwe Völker Henry Völzke Nicholas A Watkins Stefan Weiss Na Cai Kousik Kundu Stephen B Watt Klaudia Walter Alan B Zonderman Kelly Cho Yun Li Ruth J F Loos Julian C Knight Michel Georges Oliver Stegle Evangelos Evangelou Yukinori Okada David J Roberts Michael Inouye Andrew D Johnson Paul L Auer William J Astle Alexander P Reiner Adam S Butterworth Willem H Ouwehand Guillaume Lettre Vijay G Sankaran Nicole Soranzo

Cell 2020 Sep;182(5):1214-1231.e11

Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK; National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK; Department of Haematology, University of Cambridge, Cambridge, CB2 0PT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482360PMC
September 2020

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.

Authors:
Ming-Huei Chen Laura M Raffield Abdou Mousas Saori Sakaue Jennifer E Huffman Arden Moscati Bhavi Trivedi Tao Jiang Parsa Akbari Dragana Vuckovic Erik L Bao Xue Zhong Regina Manansala Véronique Laplante Minhui Chen Ken Sin Lo Huijun Qian Caleb A Lareau Mélissa Beaudoin Karen A Hunt Masato Akiyama Traci M Bartz Yoav Ben-Shlomo Andrew Beswick Jette Bork-Jensen Erwin P Bottinger Jennifer A Brody Frank J A van Rooij Kumaraswamynaidu Chitrala Kelly Cho Hélène Choquet Adolfo Correa John Danesh Emanuele Di Angelantonio Niki Dimou Jingzhong Ding Paul Elliott Tõnu Esko Michele K Evans James S Floyd Linda Broer Niels Grarup Michael H Guo Andreas Greinacher Jeff Haessler Torben Hansen Joanna M M Howson Qin Qin Huang Wei Huang Eric Jorgenson Tim Kacprowski Mika Kähönen Yoichiro Kamatani Masahiro Kanai Savita Karthikeyan Fotis Koskeridis Leslie A Lange Terho Lehtimäki Markus M Lerch Allan Linneberg Yongmei Liu Leo-Pekka Lyytikäinen Ani Manichaikul Hilary C Martin Koichi Matsuda Karen L Mohlke Nina Mononen Yoshinori Murakami Girish N Nadkarni Matthias Nauck Kjell Nikus Willem H Ouwehand Nathan Pankratz Oluf Pedersen Michael Preuss Bruce M Psaty Olli T Raitakari David J Roberts Stephen S Rich Benjamin A T Rodriguez Jonathan D Rosen Jerome I Rotter Petra Schubert Cassandra N Spracklen Praveen Surendran Hua Tang Jean-Claude Tardif Richard C Trembath Mohsen Ghanbari Uwe Völker Henry Völzke Nicholas A Watkins Alan B Zonderman Peter W F Wilson Yun Li Adam S Butterworth Jean-François Gauchat Charleston W K Chiang Bingshan Li Ruth J F Loos William J Astle Evangelos Evangelou David A van Heel Vijay G Sankaran Yukinori Okada Nicole Soranzo Andrew D Johnson Alexander P Reiner Paul L Auer Guillaume Lettre

Cell 2020 Sep;182(5):1198-1213.e14

Montreal Heart Institute, Montreal, QC H1T 1C8, Canada; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC H3T 1J4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.06.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480402PMC
September 2020

The role of polygenic susceptibility to obesity among carriers of pathogenic mutations in MC4R in the UK Biobank population.

PLoS Med 2020 07 21;17(7):e1003196. Epub 2020 Jul 21.

The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.1003196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373259PMC
July 2020

A common variant in PNPLA3 is associated with age at diagnosis of NAFLD in patients from a multi-ethnic biobank.

J Hepatol 2020 Jun 5;72(6):1070-1081. Epub 2020 Mar 5.

The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; The Mindich Child Health Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/j.jhep.2020.01.029DOI Listing
June 2020

Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia in 106,160 Patients Across Four Health Care Systems.

Am J Psychiatry 2019 10 16;176(10):846-855. Epub 2019 Aug 16.

Psychiatric and Neurodevelopmental Genetics Unit (Zheutlin, Chen, Ge, Smoller) and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (Chen); Stanley Center for Psychiatric Research, Broad Institute, Cambridge, Mass. (Zheutlin, Chen, Stahl, Smoller); Division of Genetic Medicine, Department of Medicine (Dennis, Straub, Ruderfer, Davis), Vanderbilt Genetics Institute (Dennis, Straub, Ruderfer, Davis), and Department of Biomedical Informatics (Ruderfer), Vanderbilt University Medical Center, Nashville; Department of Economics, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam (Karlsson Linnér); Autism and Developmental Medicine Institute, Geisinger, Lewisburg, Pa. (Karlsson Linnér, Chabris); Charles Bronfman Institute for Personalized Medicine (Moscati), Pamela Sklar Division of Psychiatric Genomics (Huckins, Charney, Stahl), and Department of Genetics and Genomic Sciences (Huckins, Charney, Stahl, ), Icahn School of Medicine at Mount Sinai, New York; Department of Biomedical and Translational Informatics, Geisinger, Rockville, Md. (Restrepo, Kirchner); Research Information Science and Computing, Partners HealthCare, Somerville, Mass. (Castro).

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http://dx.doi.org/10.1176/appi.ajp.2019.18091085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961974PMC
October 2019

Pharmacy students' attitudes and perceptions toward pharmacogenomics education.

Am J Health Syst Pharm 2019 05;76(11):836-845

The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.

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http://dx.doi.org/10.1093/ajhp/zxz060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523044PMC
May 2019

Pathway-based polygene risk for severe depression implicates drug metabolism in CONVERGE.

Psychol Med 2020 04 2;50(5):793-798. Epub 2019 Apr 2.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, School of Medicine, Richmond, VA, USA.

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http://dx.doi.org/10.1017/S0033291719000618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774907PMC
April 2020

Patient Adipose Stem Cell-Derived Adipocytes Reveal Genetic Variation that Predicts Antidiabetic Drug Response.

Cell Stem Cell 2019 02 10;24(2):299-308.e6. Epub 2019 Jan 10.

Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2018.11.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368460PMC
February 2019

Polygenic prediction of the phenome, across ancestry, in emerging adulthood.

Psychol Med 2018 08 27;48(11):1814-1823. Epub 2017 Nov 27.

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.

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http://dx.doi.org/10.1017/S0033291717003312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971142PMC
August 2018

Cross-Lagged Analysis of Interplay Between Differential Traits in Sibling Pairs: Validation and Application to Parenting Behavior and ADHD Symptomatology.

Behav Genet 2018 01 17;48(1):22-33. Epub 2017 Nov 17.

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.

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http://dx.doi.org/10.1007/s10519-017-9882-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846332PMC
January 2018

Cross-Disorder Psychiatric Genomics.

Curr Behav Neurosci Rep 2016 Sep 2;3(3):256-263. Epub 2016 Jul 2.

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, VA, USA; Washington Veterans Affairs Healthcare System, Washington D.C., USA; Georgetown University School of Medicine, Washington D.C., USA.

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http://dx.doi.org/10.1007/s40473-016-0084-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198908PMC
September 2016

Evaluating the dopamine hypothesis of schizophrenia in a large-scale genome-wide association study.

Schizophr Res 2016 10 20;176(2-3):136-140. Epub 2016 Jun 20.

Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, PO Box 980126, Richmond, VA 23298-0126, United States.

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http://dx.doi.org/10.1016/j.schres.2016.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026897PMC
October 2016

Personality, cognitive/psychological traits and psychiatric resilience: A multivariate twin study.

Pers Individ Dif 2016 Mar 4;91:74-79. Epub 2015 Dec 4.

Department of Psychiatry, Virginia Institute of Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.

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http://dx.doi.org/10.1016/j.paid.2015.11.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667653PMC
March 2016

CLASSIFICATION OF ANXIETY DISORDERS COMORBID WITH MAJOR DEPRESSION: COMMON OR DISTINCT INFLUENCES ON RISK?

Depress Anxiety 2016 Feb 29;33(2):120-7. Epub 2015 Sep 29.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia.

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http://dx.doi.org/10.1002/da.22432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729582PMC
February 2016

Meta-analysis of Positive and Negative Symptoms Reveals Schizophrenia Modifier Genes.

Schizophr Bull 2016 Mar 27;42(2):279-87. Epub 2015 Aug 27.

Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University School of Medicine, Richmond, VA; Mental Health Service Line, Washington VA Medical Center, Washington, DC; Department of Psychiatry, Georgetown University School of Medicine, Washington, DC.

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http://dx.doi.org/10.1093/schbul/sbv119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753595PMC
March 2016

Losing faith and finding religion: religiosity over the life course and substance use and abuse.

Drug Alcohol Depend 2014 Mar 6;136:127-34. Epub 2014 Jan 6.

Department of Family Medicine and Population Health, Division of Epidemiology, Virginia Commonwealth University, 830 East Main Street, Eighth Floor, P.O. Box 980212, Richmond, VA 23219, United States.

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http://dx.doi.org/10.1016/j.drugalcdep.2013.12.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068354PMC
March 2014