Publications by authors named "Arcadi Navarro"

100Publications

The Presence of Human Herpesvirus 6 in the Brain in Health and Disease.

Biomolecules 2020 Nov 6;10(11). Epub 2020 Nov 6.

Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), 28031 Madrid, Spain.

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http://dx.doi.org/10.3390/biom10111520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694807PMC
November 2020

Expanding the Geographic Characterisation of Epstein-Barr Virus Variation through Gene-Based Approaches.

Microorganisms 2020 Oct 29;8(11). Epub 2020 Oct 29.

Neurogenomics Group, Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute (IMIM), Department of Experimental and Health Sciences (DXECS), Universitat Pompeu Fabra, 08003 Barcelona, Spain.

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http://dx.doi.org/10.3390/microorganisms8111686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692309PMC
October 2020

The shared genetic architecture of schizophrenia, bipolar disorder and lifespan.

Hum Genet 2020 Aug 9. Epub 2020 Aug 9.

Biomedical Network Research Centre on Mental Health (CIBERSAM), Hospital Universitari Institut Pere Mata, IISPV Universitat Rovira i Virgili, Reus, Spain.

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http://dx.doi.org/10.1007/s00439-020-02213-8DOI Listing
August 2020

Extreme differences between human germline and tumor mutation densities are driven by ancestral human-specific deviations.

Nat Commun 2020 05 19;11(1):2512. Epub 2020 May 19.

Institute of Evolutionary Biology (CSIC-UPF), Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003, Barcelona, Spain.

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http://dx.doi.org/10.1038/s41467-020-16296-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237693PMC
May 2020

Targeted resequencing reveals rare variants enrichment in multiple sclerosis susceptibility genes.

Hum Mutat 2020 Jul 1;41(7):1308-1320. Epub 2020 Apr 1.

Servei de Neurologia-Neuroimmunologia, Center d'Esclerosi Múltiple de Catalunya (Cemcat), Institut de Recerca Vall d'Hebron (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/humu.24016DOI Listing
July 2020

A New Risk Variant for Multiple Sclerosis at 11q23.3 Is Associated with Expansion of Circulating Regulatory T Cells.

J Clin Med 2020 Feb 26;9(3). Epub 2020 Feb 26.

Servei de Neurologia-Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat). Institut de Recerca Vall d'Hebron (VHIR). Hospital Universitari Vall d'Hebron. Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.

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http://dx.doi.org/10.3390/jcm9030625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141122PMC
February 2020

Genome-phenome explorer (GePhEx): a tool for the visualization and interpretation of phenotypic relationships supported by genetic evidence.

Bioinformatics 2020 02;36(3):890-896

Department of Experimental and Health Sciences, Institute of Evolutionary Biology (UPF-CSIC), Universitat Pompeu Fabra, Barcelona, Catalonia 08003, Spain.

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http://dx.doi.org/10.1093/bioinformatics/btz622DOI Listing
February 2020

Reply to: Retesting the influences of mutation accumulation and antagonistic pleiotropy on human senescence and disease.

Nat Ecol Evol 2019 07 24;3(7):994-995. Epub 2019 Jun 24.

Institute of Evolutionary Biology (UPF-CSIC), Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain.

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http://dx.doi.org/10.1038/s41559-019-0926-yDOI Listing
July 2019

A pharmacogenetic study implicates in the response to Interferon-β in multiple sclerosis.

Mult Scler 2020 08 21;26(9):1074-1082. Epub 2019 Jun 21.

Laboratory of Human Genetics of Neurological Disorders, Institute of Experimental Neurology (INSPE), IRCCS San Raffaele Scientific Institute, Milan, Italy/Department of Biomedical Sciences for Health, University of Milan, Milan, Italy/Department of Neurology, IRCCS Policlinico San Donato, San Donato Milanese, Italy.

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http://dx.doi.org/10.1177/1352458519851428DOI Listing
August 2020

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.

Nat Genet 2019 02 14;51(2):245-257. Epub 2019 Jan 14.

Department of Economics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/s41588-018-0309-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713272PMC
February 2019

Effect of Collapsed Duplications on Diversity Estimates: What to Expect.

Genome Biol Evol 2018 11 1;10(11):2899-2905. Epub 2018 Nov 1.

Institute of Evolutionary Biology (Universitat Pompeu Fabra - CSIC), PRBB, Barcelona, Catalonia, Spain.

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https://academic.oup.com/gbe/advance-article/doi/10.1093/gbe
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http://dx.doi.org/10.1093/gbe/evy223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239678PMC
November 2018

FaST-LMM for Two-Way Epistasis Tests on High-Performance Clusters.

J Comput Biol 2018 08 18;25(8):862-870. Epub 2018 Jul 18.

2 Department of Experimental and Health Sciences, Pompeu Fabra University , Barcelona, Spain .

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http://dx.doi.org/10.1089/cmb.2018.0087DOI Listing
August 2018

Replicability and Prediction: Lessons and Challenges from GWAS.

Trends Genet 2018 07 30;34(7):504-517. Epub 2018 Apr 30.

CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Catalonia, Spain; Institute of Evolutionary Biology (UPF-CSIC), Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain; National Institute for Bioinformatics (INB), Barcelona, Catalonia, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), PRBB, Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.tig.2018.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003860PMC
July 2018

Author Correction: Whole genome diversity of inherited chromosomally integrated HHV-6 derived from healthy individuals of diverse geographic origin.

Sci Rep 2018 Apr 17;8(1):6357. Epub 2018 Apr 17.

Institute of Evolutionary Biology (UPF-CSIC), Departament de Ciències Experimentals i la Salut, Universitat Pompeu Fabra, PRBB, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1038/s41598-018-24603-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902477PMC
April 2018

Whole genome diversity of inherited chromosomally integrated HHV-6 derived from healthy individuals of diverse geographic origin.

Sci Rep 2018 02 22;8(1):3472. Epub 2018 Feb 22.

Institute of Evolutionary Biology (UPF-CSIC), Departament de Ciències Experimentals i la Salut, Universitat Pompeu Fabra, PRBB, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1038/s41598-018-21645-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823862PMC
February 2018

Potential damaging mutation in LRP5 from genome sequencing of the first reported chimpanzee with the Chiari malformation.

Sci Rep 2017 11 9;7(1):15224. Epub 2017 Nov 9.

Institut de Biologia Evolutiva (CSIC-UPF), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Doctor Aiguader 88, Barcelona, 08003, Spain.

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http://dx.doi.org/10.1038/s41598-017-15544-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680330PMC
November 2017

NLRP3 polymorphisms and response to interferon-beta in multiple sclerosis patients.

Mult Scler 2018 10 9;24(11):1507-1510. Epub 2017 Nov 9.

Servei de Neurologia-Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat) and Institut de Recerca Vall d'Hebron (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1177/1352458517739137DOI Listing
October 2018

Antagonistic pleiotropy and mutation accumulation influence human senescence and disease.

Nat Ecol Evol 2017 Jan 30;1(3):55. Epub 2017 Jan 30.

Institute of Evolutionary Biology (UPF-CSIC), Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Catalonia 08003, Spain.

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http://dx.doi.org/10.1038/s41559-016-0055DOI Listing
January 2017

Genetic factors affecting EBV copy number in lymphoblastoid cell lines derived from the 1000 Genome Project samples.

PLoS One 2017 27;12(6):e0179446. Epub 2017 Jun 27.

Institute of Evolutionary Biology (UPF-CSIC), Departament de Ciències Experimentals i la Salut, Universitat Pompeu Fabra, PRBB, Barcelona, Catalonia, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0179446PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487016PMC
September 2017

Erratum to: Interhemispheric gene expression differences in the cerebral cortex of humans and macaque monkeys.

Brain Struct Funct 2017 09;222(7):3367-3368

Department of Anthropology and Center for the Advanced Study of Human Paleobiology, The George Washington University, Washington, DC, 20052, USA.

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http://dx.doi.org/10.1007/s00429-017-1433-zDOI Listing
September 2017

Transcriptional network analysis in frontal cortex in Lewy body diseases with focus on dementia with Lewy bodies.

Brain Pathol 2018 05 6;28(3):315-333. Epub 2017 Apr 6.

Department of Pathology and Experimental Therapeutics, University of Barcelona, L'Hospitalet de Llobregat, Spain.

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http://dx.doi.org/10.1111/bpa.12511DOI Listing
May 2018

Interhemispheric gene expression differences in the cerebral cortex of humans and macaque monkeys.

Brain Struct Funct 2017 Sep 19;222(7):3241-3254. Epub 2017 Mar 19.

Department of Anthropology and Center for the Advanced Study of Human Paleobiology, The George Washington University, Washington, DC, 20052, USA.

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http://dx.doi.org/10.1007/s00429-017-1401-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605391PMC
September 2017

Properties of human disease genes and the role of genes linked to Mendelian disorders in complex disease aetiology.

Hum Mol Genet 2017 02;26(3):489-500

Institute of Evolutionary Biology (CSIC-UPF), Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain.

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http://dx.doi.org/10.1093/hmg/ddw405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409085PMC
February 2017

Natural Selection in the Great Apes.

Mol Biol Evol 2016 12 30;33(12):3268-3283. Epub 2016 Oct 30.

Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.

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http://dx.doi.org/10.1093/molbev/msw215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100057PMC
December 2016

Chimpanzee genomic diversity reveals ancient admixture with bonobos.

Science 2016 10 27;354(6311):477-481. Epub 2016 Oct 27.

Institut de Biologia Evolutiva (Consejo Superior de Investigaciones Científicas-Universitat Pompeu Fabra), Barcelona Biomedical Research Park, Doctor Aiguader 88, Barcelona, Catalonia 08003, Spain. National Centre for Genomic Analysis-Centre for Genomic Regulation, Barcelona Institute of Science and Technology, 08028 Barcelona, Spain. Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia 08010, Spain.

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http://dx.doi.org/10.1126/science.aag2602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546212PMC
October 2016

Differences in molecular evolutionary rates among microRNAs in the human and chimpanzee genomes.

BMC Genomics 2016 07 29;17:528. Epub 2016 Jul 29.

Department of Experimental and Health Sciences, IBE, Institute of Evolutionary Biology, (Universitat Pompeu Fabra -CSIC), Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1186/s12864-016-2863-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966751PMC
July 2016

Candidate gene study reveals DRD1 and DRD2 as putative interacting risk factors for youth depression.

Psychiatry Res 2016 Oct 20;244:71-7. Epub 2016 Jul 20.

Institute of Psychological Research (IIP), University of Costa Rica (UCR), 2060 San José, Costa Rica.

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http://dx.doi.org/10.1016/j.psychres.2016.07.032DOI Listing
October 2016

Demographic History of the Genus Pan Inferred from Whole Mitochondrial Genome Reconstructions.

Genome Biol Evol 2016 07 3;8(6):2020-30. Epub 2016 Jul 3.

Departament de Ciències Experimentals i de la Salut, Institut de Biologia Evolutiva (CSIC-UPF), Barcelona, Spain Catalan Institution of Research and Advanced Studies (ICREA), Passeig de Lluís Companys, Barcelona, Spain CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain

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http://dx.doi.org/10.1093/gbe/evw124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943195PMC
July 2016

Assessing statistical significance in multivariable genome wide association analysis.

Bioinformatics 2016 07 7;32(13):1990-2000. Epub 2016 Mar 7.

Seminar for Statistics, Department of Mathematics, ETH Zürich, Zürich 8092, Switzerland.

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http://dx.doi.org/10.1093/bioinformatics/btw128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920127PMC
July 2016

267 Spanish Exomes Reveal Population-Specific Differences in Disease-Related Genetic Variation.

Mol Biol Evol 2016 05 13;33(5):1205-18. Epub 2016 Jan 13.

Medical Genome Project, Genomics and Bioinformatics Platform of Andalusia (GBPA), Sevilla, Spain Department of Genetics, Reproduction and Fetal Medicine, Institute of Biomedicine of Seville, University Hospital Virgen del Rocío/Consejo Superior de Investigaciones Científicas/University of Seville, Sevilla, Spain Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Sevilla, Spain

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http://dx.doi.org/10.1093/molbev/msw005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839216PMC
May 2016

Pharmacogenomic study in patients with multiple sclerosis: Responders and nonresponders to IFN-β.

Neurol Neuroimmunol Neuroinflamm 2015 Oct 24;2(5):e154. Epub 2015 Sep 24.

Servei de Neurologia-Neuroimmunologia (M.F.B., S.M., J.R., X.M., M.C.), Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Institut de Recerca Vall d'Hebron (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain; Institute of Evolutionary Biology (UPF-CSIC) (C.M.-S., X.F., A.N.), PRBB, Barcelona, Spain; National Institute for Bioinformatics (C.M.-S., X.F., A.N.), Universitat Pompeu Fabra, Barcelona, Spain; Servicio de Neurología (L.L., O.F.), Instituto de Neurociencias Clínicas, Hospital Regional Universitario de Málaga, IBIMA, Málaga, Spain; Department of Neurology (U.K.Z.), University of Rostock, Rostock, Germany; Department of Neurology (J.K.), Multiple Sclerosis Centre Amsterdam, Vrije University Medical Centre, Amsterdam, the Netherlands; Pole des neurosciences et INSERM U1043 (D.B.), Université de Toulouse III, Hopital Purpan, Toulouse, France; Neuroinmunología (J.A.G.-M., A.J.S.), Hospital Universitario Puerta de Hierro, Madrid, Spain; Servicio de Neurología (E.U., R.A.-L.), Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain; Department of Neurology and Immunology (L.M.V., J.C.A.-C.), Hospital Ramón y Cajal, IRYCIS, Madrid, Spain; Department of Neurology (J.L.-S.), John Hunter Hospital, Newcastle, Australia; Hunter Medical Research Institute (J.L.-S.), University Newcastle, Australia; University Newcastle (J.L.-S.), Callaghan Campus, Australia; Neurogenomiks Group (K.V.), Universidad del País Vasco (UPV/EHU), Leioa, Spain; IKERBASQUE (K.V.), Basque Foundation for Science, Bilbao, Spain; Achucarro Basque Center for Neuroscience (K.V.), Zamudio, Spain; Servicio de Neurología (A.R.-A.), Hospital de Basurto, Bilbao, Spain; Clinic of Neurology (J.S.D.), Clinical Centre of Serbia (CCS), Faculty of Medicine, University of Belgrade, Serbia; Laboratory of Genetics of Neurological Complex Disorders and Department of Neuro-rehabilitation (F.M.B

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http://dx.doi.org/10.1212/NXI.0000000000000154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582905PMC
October 2015

SeDuS: segmental duplication simulator.

Bioinformatics 2016 Jan 10;32(1):148-50. Epub 2015 Sep 10.

Institute of Evolutionary Biology (Universitat Pompeu Fabra - CSIC), PRBB, 08003, National Institute for Bioinformatics, 08003, Institució Catalana de Recerca i Estudis Avançats (ICREA), 08010 and Centre for Genomic Regulation (CRG), 08003, Barcelona, Spain.

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http://dx.doi.org/10.1093/bioinformatics/btv481DOI Listing
January 2016

Genetic and Clinical Factors Associated with Chronic Postsurgical Pain after Hernia Repair, Hysterectomy, and Thoracotomy: A Two-year Multicenter Cohort Study.

Anesthesiology 2015 May;122(5):1123-41

From the Department of Anesthesiology, Parc de Salut MAR, Institut Municipal d'Investigació Mèdica, Universitat Autònoma de Barcelona, Barcelona, Spain (A.M., J. Cantillo); Department of Anesthesiology, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain (G.R., J. Canet); Department of Anesthesiology, Fundació Puigvert, Barcelona, Spain (S.S.); Genomic Genetics International, Barcelona, Spain (J.I.L.); and Department of Experimental and Health Sciences (Universitat Pompeu Fabra) and Institute of Evolutionary Biology (Universitat Pompeu Fabra-CSIC), Centre de Regulació Genòmica, National Institute for Bioinformatics, Institució Catalana de Recerca I Estudis Avançats, Barcelona, Spain (A.N.).

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http://dx.doi.org/10.1097/ALN.0000000000000611DOI Listing
May 2015

Mendelian genes for Parkinson's disease contribute to the sporadic forms of the disease.

Hum Mol Genet 2015 Apr 11;24(7):2023-34. Epub 2014 Dec 11.

Institute of Evolutionary Biology (CSIC-UPF), Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain,

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http://dx.doi.org/10.1093/hmg/ddu616DOI Listing
April 2015

Integrating genomics into evolutionary medicine.

Curr Opin Genet Dev 2014 Dec 16;29:97-102. Epub 2014 Sep 16.

Institute of Evolutionary Biology (UPF-CSIC-PRBB), Barcelona, Catalonia, Spain; Center for Genomic Regulation (CRG), Barcelona, Catalonia, Spain; National Institute for Bioinformatics (INB), Barcelona, Catalonia, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.gde.2014.08.009DOI Listing
December 2014

Interplay of interlocus gene conversion and crossover in segmental duplications under a neutral scenario.

G3 (Bethesda) 2014 Jun 6;4(8):1479-89. Epub 2014 Jun 6.

Institute of Evolutionary Biology (Universitat Pompeu Fabra - CSIC), PRBB, Barcelona, Catalonia, Spain, 08003 National Institute for Bioinformatics (INB), Barcelona, Catalonia, Spain Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spain Centre for Genomic Regulation (CRG), Barcelona, Catalonia, Spain, 08003

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http://g3journal.org/lookup/doi/10.1534/g3.114.012435
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http://dx.doi.org/10.1534/g3.114.012435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132178PMC
June 2014

Pool and conquer: new tricks for (c)old problems.

Mol Ecol 2014 Apr;23(7):1653-5

Institute of Evolutionary Biology (Universitat Pompeu Fabra-CSIC), PRBB, Doctor Aiguader 88, Barcelona, 08003, Catalonia, Spain; Centre de Regulació Genòmica (CRG), Barcelona, Spain; National Institute for Bioinformatics (INB), Barcelona, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.

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http://dx.doi.org/10.1111/mec.12685DOI Listing
April 2014

Great ape genetic diversity and population history.

Nature 2013 Jul 3;499(7459):471-5. Epub 2013 Jul 3.

Institut de Biologia Evolutiva, CSIC-Universitat Pompeu Fabra, PRBB, Doctor Aiguader 88, Barcelona, Catalonia 08003, Spain.

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http://dx.doi.org/10.1038/nature12228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822165PMC
July 2013

High trans-ethnic replicability of GWAS results implies common causal variants.

PLoS Genet 2013 Jun 13;9(6):e1003566. Epub 2013 Jun 13.

Institute of Evolutionary Biology (Universitat Pompeu Fabra-CSIC), PRBB, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1371/journal.pgen.1003566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681663PMC
June 2013

The genome of melon (Cucumis melo L.).

Proc Natl Acad Sci U S A 2012 Jul 2;109(29):11872-7. Epub 2012 Jul 2.

Institut de Recerca i Tecnologia Agroalimentàries, Centre for Research in Agricultural Genomics Consejo Superior de Investigaciones Científicas-Institut de Recerca i Tecnologia Agroalimentàries-Universitat Autònoma de Barcelona-Universitat de Barcelona, 08193 Barcelona, Spain.

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http://dx.doi.org/10.1073/pnas.1205415109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406823PMC
July 2012

Genome-wide association studies pipeline (GWASpi): a desktop application for genome-wide SNP analysis and management.

Bioinformatics 2011 Jul 17;27(13):1871-2. Epub 2011 May 17.

Institut de Biología Evolutiva, Universitat Pompeu Fabra, Biomedical Research Park (PRBB), Barcelona, Spain.

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http://dx.doi.org/10.1093/bioinformatics/btr301DOI Listing
July 2011

Comparative and demographic analysis of orang-utan genomes.

Authors:
Devin P Locke LaDeana W Hillier Wesley C Warren Kim C Worley Lynne V Nazareth Donna M Muzny Shiaw-Pyng Yang Zhengyuan Wang Asif T Chinwalla Pat Minx Makedonka Mitreva Lisa Cook Kim D Delehaunty Catrina Fronick Heather Schmidt Lucinda A Fulton Robert S Fulton Joanne O Nelson Vincent Magrini Craig Pohl Tina A Graves Chris Markovic Andy Cree Huyen H Dinh Jennifer Hume Christie L Kovar Gerald R Fowler Gerton Lunter Stephen Meader Andreas Heger Chris P Ponting Tomas Marques-Bonet Can Alkan Lin Chen Ze Cheng Jeffrey M Kidd Evan E Eichler Simon White Stephen Searle Albert J Vilella Yuan Chen Paul Flicek Jian Ma Brian Raney Bernard Suh Richard Burhans Javier Herrero David Haussler Rui Faria Olga Fernando Fleur Darré Domènec Farré Elodie Gazave Meritxell Oliva Arcadi Navarro Roberta Roberto Oronzo Capozzi Nicoletta Archidiacono Giuliano Della Valle Stefania Purgato Mariano Rocchi Miriam K Konkel Jerilyn A Walker Brygg Ullmer Mark A Batzer Arian F A Smit Robert Hubley Claudio Casola Daniel R Schrider Matthew W Hahn Victor Quesada Xose S Puente Gonzalo R Ordoñez Carlos López-Otín Tomas Vinar Brona Brejova Aakrosh Ratan Robert S Harris Webb Miller Carolin Kosiol Heather A Lawson Vikas Taliwal André L Martins Adam Siepel Arindam Roychoudhury Xin Ma Jeremiah Degenhardt Carlos D Bustamante Ryan N Gutenkunst Thomas Mailund Julien Y Dutheil Asger Hobolth Mikkel H Schierup Oliver A Ryder Yuko Yoshinaga Pieter J de Jong George M Weinstock Jeffrey Rogers Elaine R Mardis Richard A Gibbs Richard K Wilson

Nature 2011 Jan;469(7331):529-33

The Genome Center at Washington University, Washington University School of Medicine, 4444 Forest Park Avenue, Saint Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1038/nature09687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060778PMC
January 2011

Recent human evolution has shaped geographical differences in susceptibility to disease.

BMC Genomics 2011 Jan 24;12:55. Epub 2011 Jan 24.

Institute of Evolutionary Biology (UPF-CSIC), PRBB, Doctor Aiguader 88, 08003, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1186/1471-2164-12-55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039608PMC
January 2011

Selection upon genome architecture: conservation of functional neighborhoods with changing genes.

PLoS Comput Biol 2010 Oct 7;6(10):e1000953. Epub 2010 Oct 7.

Department of Bioinformatics and Genomics, Centro de Investigación Príncipe Felipe (CIPF), Valencia, Spain.

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http://dx.doi.org/10.1371/journal.pcbi.1000953DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951340PMC
October 2010

Gender-associated differences of perforin polymorphisms in the susceptibility to multiple sclerosis.

J Immunol 2010 Nov 4;185(9):5392-404. Epub 2010 Oct 4.

Centre d'Esclerosi Múltiple de Catalunya, Unitat de Neuroimmunologia Clínica, Hospital Universitari Vall d'Hebron, Barcelona, Spain.

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http://dx.doi.org/10.4049/jimmunol.1000102DOI Listing
November 2010

Chromosomal speciation revisited: rearranging theory with pieces of evidence.

Trends Ecol Evol 2010 Nov 1;25(11):660-9. Epub 2010 Oct 1.

Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.tree.2010.07.008DOI Listing
November 2010

Genome-wide scan of 500,000 single-nucleotide polymorphisms among responders and nonresponders to interferon beta therapy in multiple sclerosis.

Arch Neurol 2009 Aug;66(8):972-8

Centre d'Esclerosi Múltiple de Catalunya, Unitat de Neuroimmunologia Clínica, Hospital Universitari Vall d'Hebron, Edifici Escola d'Infermeria 2 feminine planta, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain.

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http://dx.doi.org/10.1001/archneurol.2009.150DOI Listing
August 2009

Positive selection and gene conversion drive the evolution of a brain-expressed snoRNAs cluster.

Mol Biol Evol 2009 Nov 3;26(11):2563-71. Epub 2009 Aug 3.

Genetic Causes of Disease Group, Genes and Disease Program, Centre for Genomic Regulation (CRG), Barcelona, Spain.

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http://dx.doi.org/10.1093/molbev/msp173DOI Listing
November 2009

Decay of linkage disequilibrium within genes across HGDP-CEPH human samples: most population isolates do not show increased LD.

BMC Genomics 2009 Jul 28;10:338. Epub 2009 Jul 28.

Institut de Biologia Evolutiva (UPF-CSIC), Departament de Ciències Experimentals i de Salut, Universitat Pompeu Fabra, Parc de Recerca Biomèdica de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1186/1471-2164-10-338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723139PMC
July 2009

Genoeconomics: promises and caveats for a new field.

Authors:
Arcadi Navarro

Ann N Y Acad Sci 2009 Jun;1167:57-65

Institució Catalana de Recerca i Estudis Avançats and Institut de Biologia Evolututiva, Universitat Pompeu Fabra i Consejo Superior de Investigaciones Científicas, Barcelona, Spain.

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http://dx.doi.org/10.1111/j.1749-6632.2009.04732.xDOI Listing
June 2009

Foreword: Values, empathy, and fairness across social barriers.

Ann N Y Acad Sci 2009 Jun;1167:1-4

University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2009.04879.xDOI Listing
June 2009

Interrogating 11 fast-evolving genes for signatures of recent positive selection in worldwide human populations.

Mol Biol Evol 2009 Oct 3;26(10):2285-97. Epub 2009 Jul 3.

Departament de Ciències Experimentals i de la Salut, Institut de Biologia Evolutiva (UPF-CSIC), Universitat Pompeu Fabra, Barcelona, Spain.

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https://academic.oup.com/mbe/article-lookup/doi/10.1093/molb
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http://dx.doi.org/10.1093/molbev/msp134DOI Listing
October 2009

Allele-specific gene expression is widespread across the genome and biological processes.

PLoS One 2009 7;4(1):e4150. Epub 2009 Jan 7.

Neuroimmunology Laboratory, Center for Applied Medical Research, CIMA, University of Navarra, Pamplona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0004150PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613524PMC
February 2009

The measurement of the lactonase activity of paraoxonase-1 in the clinical evaluation of patients with chronic liver impairment.

Clin Biochem 2009 Jan 21;42(1-2):91-8. Epub 2008 Oct 21.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigacions Sanitàries Pere Virgili, Universitat Rovira i Virgili, Reus, Spain.

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http://dx.doi.org/10.1016/j.clinbiochem.2008.09.120DOI Listing
January 2009

The genomic distribution of intraspecific and interspecific sequence divergence of human segmental duplications relative to human/chimpanzee chromosomal rearrangements.

BMC Genomics 2008 Aug 12;9:384. Epub 2008 Aug 12.

Unitat de Biologia Evolutiva Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1186/1471-2164-9-384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542386PMC
August 2008

Balancing selection is the main force shaping the evolution of innate immunity genes.

J Immunol 2008 Jul;181(2):1315-22

Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Unitat de Biologia Evolutiva, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.4049/jimmunol.181.2.1315DOI Listing
July 2008

On the association between chromosomal rearrangements and genic evolution in humans and chimpanzees.

Genome Biol 2007 ;8(10):R230

Unitat de Biologia Evolutiva Departament de Ciències Experimentals i de la Salut, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Parc de Recerca Biomèdica de Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1186/gb-2007-8-10-r230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246304PMC
May 2008

Extreme individual marker F(ST )values do not imply population-specific selection in humans: the NRG1 example.

Hum Genet 2007 Jul 25;121(6):759-62. Epub 2007 Apr 25.

Unitat de Biologia Evolutiva, Universitat Pompeu Fabra, Doctor Aiguader 88, Barcelona, 08003, Spain.

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http://dx.doi.org/10.1007/s00439-007-0364-9DOI Listing
July 2007

Patterns and rates of intron divergence between humans and chimpanzees.

Genome Biol 2007 ;8(2):R21

Unitat de Biologia Evolutiva, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Carrer Dr Aiguader 88, 08003 Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1186/gb-2007-8-2-r21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852421PMC
July 2007

Frequent appearance of novel protein-coding sequences by frameshift translation.

Genomics 2006 Dec 4;88(6):690-697. Epub 2006 Aug 4.

The Centre for Applied Genomics, Program in Genetics and Genomic Biology, The Hospital for Sick Children, Toronto, Canada ON M5G 1L7; Department of Molecular and Medical Genetics, University of Toronto, Toronto, Canada ON M5S 1A8. Electronic address:

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http://dx.doi.org/10.1016/j.ygeno.2006.06.009DOI Listing
December 2006

The portability of tagSNPs across populations: a worldwide survey.

Genome Res 2006 Mar 8;16(3):323-30. Epub 2006 Feb 8.

Unitat de Biologia Evolutiva, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, 08003 Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1101/gr.4138406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1415211PMC
March 2006

The prion protein gene in humans revisited: lessons from a worldwide resequencing study.

Genome Res 2006 Feb 20;16(2):231-9. Epub 2005 Dec 20.

Unitat de Biologia Evolutiva, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, 08003 Barcelona, Spain.

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http://dx.doi.org/10.1101/gr.4345506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361719PMC
February 2006

Murine segmental duplications are hot spots for chromosome and gene evolution.

Genomics 2005 Dec 26;86(6):692-700. Epub 2005 Oct 26.

Genes and Disease Program, Center for Genomic Regulation, Passeig Marítim 37-49, 08003 Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1016/j.ygeno.2005.08.008DOI Listing
December 2005

Association Cluster Detector: a tool for heuristic detection of significance clusters in whole-genome scans.

Bioinformatics 2005 Sep;21 Suppl 2:ii180-1

Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain.

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http://dx.doi.org/10.1093/bioinformatics/bti1118DOI Listing
September 2005

Chromosomal rearrangements are associated with higher rates of molecular evolution in mammals.

Gene 2005 Jul;353(2):147-54

Unitat de Biologia Evolutiva Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Doctor Aiguader 80, 08003 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.gene.2005.05.007DOI Listing
July 2005