Publications by authors named "Apparao Kummarapurugu"

15Publications

Polysulfated Hyaluronan GM-1111 Inhibits Elastase and Improves Rheology in CF Sputum.

Authors:
Apparao B Kummarapurugu Shuo Zheng Abigail Pulsipher Justin R Savage Jonathan Ma Bruce K Rubin Thomas P Kennedy Judith A Voynow

Am J Respir Cell Mol Biol 2020 Dec 2. Epub 2020 Dec 2.

Children's Hospital of Richmond at Virginia Commonwealth University, 480853, Division of Pediatric Pulmonology, Richmond, Virginia, United States;

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December 2020

Neutrophil Extracellular Traps Increase Airway Mucus Viscoelasticity and Slow Mucus Particle Transit.

Authors:
Rosalie S Linssen Guihong Chai Jonathan Ma Apparao B Kummarapurugu Job B M van Woensel Reinout A Bem Logan Kaler Gregg A Duncan Lei Zhou Bruce K Rubin Qingguo Xu

Am J Respir Cell Mol Biol 2021 Jan;64(1):69-78

Department of Pharmaceutics.

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January 2021

Glycosaminoglycans as Multifunctional Anti-Elastase and Anti-Inflammatory Drugs in Cystic Fibrosis Lung Disease.

Authors:
Judith A Voynow Shuo Zheng Apparao B Kummarapurugu

Front Pharmacol 2020 8;11:1011. Epub 2020 Jul 8.

Department of Pediatric Pulmonology, Children's Hospital of Richmond at VCU, Richmond, VA, United States.

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July 2020

On the Process of Discovering Leads That Target the Heparin-Binding Site of Neutrophil Elastase in the Sputum of Cystic Fibrosis Patients.

Authors:
Shravan Morla Nehru Viji Sankaranarayanan Daniel K Afosah Megh Kumar Apparao B Kummarapurugu Judith A Voynow Umesh R Desai

J Med Chem 2019 06 28;62(11):5501-5511. Epub 2019 May 28.

Department of Medicinal Chemistry , Virginia Commonwealth University , Richmond , Virginia 23298 , United States.

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June 2019

Correction: Determination of ferric ions using surface-enhanced Raman scattering based on desferrioxamine-functionalized silver nanoparticles.

Authors:
Fei Yan C V Gopal Reddy Yam K Shrestha Charina L Spurgeon Apparao B Kummarapurugu Bernard M Fischer Tuan Vo-Dinh

Chem Commun (Camb) 2018 09;54(78):11053

Department of Chemistry, North Carolina Central University, Durham, North Carolina, USA.

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September 2018

Molecular principles for heparin oligosaccharide-based inhibition of neutrophil elastase in cystic fibrosis.

Authors:
Apparao B Kummarapurugu Daniel K Afosah Nehru Viji Sankaranarayanan Rahaman Navaz Gangji Shuo Zheng Thomas Kennedy Bruce K Rubin Judith A Voynow Umesh R Desai

J Biol Chem 2018 08 14;293(32):12480-12490. Epub 2018 Jun 14.

the Department of Medicinal Chemistry, Virginia Commonwealth University, Richmond, Virginia 23298,

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August 2018

Neutrophil elastase correlates with increased sphingolipid content in cystic fibrosis sputum.

Authors:
Sophia Karandashova Apparao Kummarapurugu Shuo Zheng Le Kang Shumei Sun Bruce K Rubin Judith A Voynow

Pediatr Pulmonol 2018 07 6;53(7):872-880. Epub 2018 Apr 6.

Division of Pediatric Pulmonology, Children's Hospital of Richmond at VCU, Richmond, Virginia.

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July 2018

High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.

Authors:
Apparao B Kummarapurugu Shuo Zheng Julie Ledford Sophia Karandashova Judith A Voynow

Am J Respir Cell Mol Biol 2018 01;58(1):126-128

1 Children's Hospital of Richmond at Virginia Commonwealth University Richmond, Virginia.

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January 2018

Neutrophil elastase increases airway ceramide levels via upregulation of serine palmitoyltransferase.

Authors:
Sophia Karandashova Apparao B Kummarapurugu Shuo Zheng Charles E Chalfant Judith A Voynow

Am J Physiol Lung Cell Mol Physiol 2018 01 12;314(1):L206-L214. Epub 2017 Oct 12.

Division of Pediatric Pulmonary Medicine, Children's Hospital of Richmond at Virginia Commonwealth University , Richmond, Virginia.

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January 2018

2-O, 3-O Desulfated Heparin Blocks High Mobility Group Box 1 Release by Inhibition of p300 Acetyltransferase Activity.

Authors:
Shuo Zheng Apparao B Kummarapurugu Daniel K Afosah Nehru Viji Sankaranarayanan Rio S Boothello Umesh R Desai Thomas Kennedy Judith A Voynow

Am J Respir Cell Mol Biol 2017 01;56(1):90-98

1 Department of Pediatrics and.

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January 2017

Diacetyl induces amphiregulin shedding in pulmonary epithelial cells and in experimental bronchiolitis obliterans.

Authors:
Francine L Kelly Jesse Sun Bernard M Fischer Judith A Voynow Apparao B Kummarapurugu Helen L Zhang Julia L Nugent Robert F Beasley Tereza Martinu William M Gwinn Daniel L Morgan Scott M Palmer

Am J Respir Cell Mol Biol 2014 Oct;51(4):568-74

Divisions of 1 Pulmonary, Allergy, and Critical Care Medicine, and.

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October 2014

2-O, 3-O-desulfated heparin inhibits neutrophil elastase-induced HMGB-1 secretion and airway inflammation.

Authors:
Kathryn L Griffin Bernard M Fischer Apparao B Kummarapurugu Shuo Zheng Thomas P Kennedy Narayanam V Rao W Michael Foster Judith A Voynow

Am J Respir Cell Mol Biol 2014 Apr;50(4):684-9

1 Department of Pediatrics, Duke University Medical Center.

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April 2014

Increased expression of senescence markers in cystic fibrosis airways.

Authors:
Bernard M Fischer Jessica K Wong Simone Degan Apparao B Kummarapurugu Shuo Zheng Prashamsha Haridass Judith A Voynow

Am J Physiol Lung Cell Mol Physiol 2013 Mar 11;304(6):L394-400. Epub 2013 Jan 11.

Division of Pediatric Pulmonary and Sleep Medicine, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA.

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March 2013

NADPH:quinone oxidoreductase 1 regulates host susceptibility to ozone via isoprostane generation.

Authors:
Apparao B Kummarapurugu Bernard M Fischer Shuo Zheng Ginger L Milne Andrew J Ghio Erin N Potts-Kant W Michael Foster Erik J Soderblom Laura G Dubois M Arthur Moseley J Will Thompson Judith A Voynow

J Biol Chem 2013 Feb 28;288(7):4681-91. Epub 2012 Dec 28.

Division of Pediatric Pulmonary and Sleep Medicine, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27710, USA.

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February 2013

Isoprostanes and asthma.

Authors:
Judith A Voynow Apparao Kummarapurugu

Biochim Biophys Acta 2011 Nov 8;1810(11):1091-5. Epub 2011 May 8.

Division of Pediatric Pulmonary and Sleep Medicine, Duke University Medical Center, Durham, NC 27710, USA.

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November 2011