Publications by authors named "Apparao Kummarapurugu"

15Publications

Polysulfated Hyaluronan GM-1111 Inhibits Elastase and Improves Rheology in CF Sputum.

Am J Respir Cell Mol Biol 2020 Dec 2. Epub 2020 Dec 2.

Children's Hospital of Richmond at Virginia Commonwealth University, 480853, Division of Pediatric Pulmonology, Richmond, Virginia, United States;

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December 2020

Glycosaminoglycans as Multifunctional Anti-Elastase and Anti-Inflammatory Drugs in Cystic Fibrosis Lung Disease.

Front Pharmacol 2020 8;11:1011. Epub 2020 Jul 8.

Department of Pediatric Pulmonology, Children's Hospital of Richmond at VCU, Richmond, VA, United States.

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July 2020

On the Process of Discovering Leads That Target the Heparin-Binding Site of Neutrophil Elastase in the Sputum of Cystic Fibrosis Patients.

J Med Chem 2019 06 28;62(11):5501-5511. Epub 2019 May 28.

Department of Medicinal Chemistry , Virginia Commonwealth University , Richmond , Virginia 23298 , United States.

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June 2019

Neutrophil elastase correlates with increased sphingolipid content in cystic fibrosis sputum.

Pediatr Pulmonol 2018 07 6;53(7):872-880. Epub 2018 Apr 6.

Division of Pediatric Pulmonology, Children's Hospital of Richmond at VCU, Richmond, Virginia.

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July 2018

High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.

Am J Respir Cell Mol Biol 2018 01;58(1):126-128

1 Children's Hospital of Richmond at Virginia Commonwealth University Richmond, Virginia.

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January 2018

Neutrophil elastase increases airway ceramide levels via upregulation of serine palmitoyltransferase.

Am J Physiol Lung Cell Mol Physiol 2018 01 12;314(1):L206-L214. Epub 2017 Oct 12.

Division of Pediatric Pulmonary Medicine, Children's Hospital of Richmond at Virginia Commonwealth University , Richmond, Virginia.

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January 2018

Increased expression of senescence markers in cystic fibrosis airways.

Am J Physiol Lung Cell Mol Physiol 2013 Mar 11;304(6):L394-400. Epub 2013 Jan 11.

Division of Pediatric Pulmonary and Sleep Medicine, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA.

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March 2013

NADPH:quinone oxidoreductase 1 regulates host susceptibility to ozone via isoprostane generation.

J Biol Chem 2013 Feb 28;288(7):4681-91. Epub 2012 Dec 28.

Division of Pediatric Pulmonary and Sleep Medicine, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27710, USA.

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February 2013

Isoprostanes and asthma.

Biochim Biophys Acta 2011 Nov 8;1810(11):1091-5. Epub 2011 May 8.

Division of Pediatric Pulmonary and Sleep Medicine, Duke University Medical Center, Durham, NC 27710, USA.

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November 2011