Aparna Vasanthakumar

Aparna Vasanthakumar

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Aparna Vasanthakumar

Aparna Vasanthakumar

Publications by authors named "Aparna Vasanthakumar"

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Erratum to "5-hydroxymethylcytosine in cancer: Significance in diagnosis and therapy" [Cancer Genet 208 (2015):167-177].

Cancer Genet 2016 Apr 12;209(4):177. Epub 2016 Feb 12.

Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.cancergen.2016.02.001DOI Listing
April 2016

Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice.

Blood 2016 Jan 7;127(3):310-3. Epub 2015 Dec 7.

Section of Hematology/Oncology, Department of Medicine, The University of Chicago Medicine Comprehensive Cancer Center, and Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL.

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http://dx.doi.org/10.1182/blood-2015-03-635599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722284PMC
January 2016

Epigenetic Control of Apolipoprotein E Expression Mediates Gender-Specific Hematopoietic Regulation.

Stem Cells 2015 Dec 10;33(12):3643-54. Epub 2015 Oct 10.

Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1002/stem.2214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713251PMC
December 2015

DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID.

Cell Rep 2015 Sep 10;12(12):2086-98. Epub 2015 Sep 10.

Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY 10065, USA; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.08.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591215PMC
September 2015

TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor-Binding Sites in Chronic Myelomonocytic Leukemia.

Cancer Res 2015 Jul 13;75(14):2833-43. Epub 2015 May 13.

Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, Pennsylvania. Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-0739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506197PMC
July 2015

5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy.

Cancer Genet 2015 May 3;208(5):167-77. Epub 2015 Mar 3.

Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2015.02.009DOI Listing
May 2015

TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.

Cell Rep 2014 Jun 15;7(5):1343-1352. Epub 2014 May 15.

Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL 60637, USA; Committee on Cancer Biology, University of Chicago, Chicago, IL 60637, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247140034
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http://dx.doi.org/10.1016/j.celrep.2014.04.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516227PMC
June 2014

On the origin of leukemic species.

Cell Stem Cell 2014 Apr;14(4):421-2

Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL 60637, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2014.03.008DOI Listing
April 2014

Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer.

Nucleic Acids Res 2013 Sep 16;41(16):e157. Epub 2013 Jul 16.

Cancer Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA, Department of Genetics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA, Department of Pathology, Johns Hopkins School of Medicine, 1550 Orleans Street, Baltimore MD 21231, USA, Department of Medicine, University of Chicago, 5841 S. Maryland Avenue, Chicago, IL 60637, USA and Department of Medicine, Hematology and Medical Oncology, Mount Sinai School of Medicine, 1470 Madison Avenue, New York, NY 10029, USA.

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http://dx.doi.org/10.1093/nar/gkt601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763560PMC
September 2013

Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma.

Cancer Discov 2013 Sep 16;3(9):1002-19. Epub 2013 Aug 16.

1Division of Hematology and Oncology, Department of Medicine, 2Division of Biostatistics and Epidemiology, Department of Public Health, 3Weill Cornell Cancer Center, and Departments of 4Pathology and 5Pharmacology, Weill Cornell Medical College, Cornell University, New York, New York; 6Section of Hematology/Oncology, Department of Medicine, The University of Chicago; Department of Pathology, Northwestern University, Chicago, Illinois; 8Institute for Research in Immunology and Cancer and Department of Pathology and Cell Biology, University of Montreal, Montreal, Quebec; 9Centre for Lymphoid Cancer, BC Cancer Agency, Vancouver, British Columbia, Canada; 10IBM Research, Rio de Janeiro, Brazil; and 11Department of Oncological Sciences, University of Turin, Turin, Italy.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770813PMC
September 2013

Perturbations of 5-hydroxymethylcytosine patterning in hematologic malignancies.

Semin Hematol 2013 Jan;50(1):61-9

Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL 60637-1470, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00371963130000
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http://dx.doi.org/10.1053/j.seminhematol.2013.01.004DOI Listing
January 2013

Selective inhibition of the citrate-to-isocitrate reaction of cytosolic aconitase by phosphomimetic mutation of serine-711.

Proc Natl Acad Sci U S A 2004 Jul 19;101(30):10907-12. Epub 2004 Jul 19.

Department of Nutritional Sciences, University of Wisconsin, Madison, 53706, USA.

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http://dx.doi.org/10.1073/pnas.0404308101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC503718PMC
July 2004