Publications by authors named "Antti J Kangas"

96Publications

Direct Estimation of HDL-Mediated Cholesterol Efflux Capacity from Serum.

Clin Chem 2019 08 17;65(8):1042-1050. Epub 2019 Apr 17.

Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, Oulu, Finland;

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http://www.clinchem.org/lookup/doi/10.1373/clinchem.2018.299
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http://dx.doi.org/10.1373/clinchem.2018.299222DOI Listing
August 2019

Effect of Dietary Counseling on a Comprehensive Metabolic Profile from Childhood to Adulthood.

J Pediatr 2018 04 1;195:190-198.e3. Epub 2018 Feb 1.

Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.

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http://dx.doi.org/10.1016/j.jpeds.2017.11.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864506PMC
April 2018

DHA mediates the protective effect of fish consumption on new episodes of depression among women.

Br J Nutr 2017 Nov;118(9):743-749

1Menzies Institute for Medical Research,University of Tasmania,Private Bag 23, Hobart, Tasmania 7000,Australia.

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https://www.cambridge.org/core/product/identifier/S000711451
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http://dx.doi.org/10.1017/S0007114517002768DOI Listing
November 2017

The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection.

Cell Syst 2015 Oct 22;1(4):293-301. Epub 2015 Oct 22.

Centre for Systems Genomics, School of BioSciences, The University of Melbourne, Parkville, 3010 Victoria, Australia; Department of Pathology, The University of Melbourne, Parkville, 3010 Victoria, Australia; Department of Microbiology and Immunology, The University of Melbourne, Parkville, 3010 Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2015.09.007DOI Listing
October 2015

Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase-Independent Effects.

Circ Cardiovasc Genet 2016 Jun 25;9(3):231-9. Epub 2016 Apr 25.

From the MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol (F.D., G.D.S., M.A.-K., D.A.L., T.R.G., N.J.T.); Institute of Cardiovascular Science, University College London, London, United Kingdom (F.D., C.D., J.-P.C.); Computational Medicine, Faculty of Medicine, University of Oulu & Biocenter Oulu, Oulu (M.A.-K., J.K., P.W., P.S., A.J.K.); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio (M.A.-K., J.K., P.S.); Public Health Genomics Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland (J.K.); and Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom (C.D., J.-P.C.).

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http://dx.doi.org/10.1161/CIRCGENETICS.115.001302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920206PMC
June 2016

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase.

J Am Coll Cardiol 2016 Mar;67(10):1200-1210

Computational Medicine, Institute of Health Sciences, University of Oulu and Biocenter Oulu, Oulu, Finland; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland; Oulu University Hospital, Oulu, Finland; Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom; Computational Medicine, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2015.12.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783625PMC
March 2016

Abdominal obesity and circulating metabolites: A twin study approach.

Metabolism 2016 Mar 31;65(3):111-21. Epub 2015 Oct 31.

Obesity Research Unit, Research programs unit, Diabetes and Obesity, University of Helsinki, Helsinki, Finland; Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland; Department of Medicine, Division of Endocrinology, Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.metabol.2015.10.027DOI Listing
March 2016

Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study.

Lancet Diabetes Endocrinol 2015 Jul 18;3(7):526-534. Epub 2015 Jun 18.

​ (J C Chambers PhD, M Loh PhD, B Lehne PhD, W R Scott MRCP, W Zhang PhD, G Campanella MSc, M Chadeau-Hyam PhD, U Afzal MRCP, Prof P Froguel PhD, Prof P Vineis MD, Prof M-R Jarvelin PhD, Prof P Elliott PhD) (J C Chambers, Prof M-R Jarvelin, Prof P Elliott, Prof J S Kooner FRCP) (W R Scott, S-T Tan MRCP, Prof J Scott PhD, Prof J S Kooner) (J Abbott PhD) (J C Chambers, W Zhang, S-T Tan, U Afzal, Prof J S Kooner) (J C Chambers, P Punjabi FRCS, Prof J S Kooner) (M Loh) (C Blancher PhD) (A Drong PhD, Prof M I McCarthy MD) (Prof M I McCarthy) (J Kriebel PhD, S Wahl MSc, C Gieger PhD, H Grallert PhD) (C Gieger) (J Kriebel, S Wahl, C Gieger, B Thorand PhD, H Grallert) (H Prokisch PhD) (J Kriebel, S Wahl, B Thorand, H Grallert) (V Motta PhD, F Rota PhD, L Tarantini PhD, B Albetti PhD, Prof P A Bertazzi MD, V Bollati PhD) (Prof M Ala-Korpela PhD) (H R Elliott Dip Biol, R C Richmond BA, R Caiazzo PhD, T R Gaunt FRCP, Prof C L Relton PhD) (L Yengo PhD, Prof F Pattou PhD, R Caiazzo, S Cauchi PhD, Prof P Froguel) (L Yengo, S Cauchi, Prof P Froguel) (L Yengo, Prof F Pattou, S Cauchi, Prof P Froguel) (M Adamowicz-Brice PhD, Prof T J Aitman PhD) (K Bozaoglu PhD, R Caiazzo, J Jowett PhD) (Z Y Mok BSc, H K Ng BSc, M A Rozario BSc, R Soong PhD) (E-S Tai PhD) (E-S Tai) (Prof F Pattou) (H Prokisch) (Prof M Ala-Korpela, A J Kangas MSc, P Soininen PhD) (M Loh, Prof M-R Jarvelin) (Prof M-R Jarvelin) (Prof M Ala-Korpela, P Soininen) (Prof M-R Jarvelin) (Prof M Ala-Korpela) (Prof O Ammerpohl PhD) (Prof C Schafmayer MD) (Prof J Danesh FRCP) (Prof S de Lusignan PhD, Prof S Jones PhD) (Prof T Illig PhD) (S Jha MRCP) (A Kasturiratne MD, Prof A R Wickremasinghe PhD) (N Kato PhD) (N Kotea PhD) (S Kowlessur Dip Pub Health Admin) (J Pitkäniemi PhD) (Prof J Tuomilehto PhD) (J Pitkäniemi) (D Saleheen PhD) (D Saleheen) (D Saleheen) (E-S Tai) (Prof S A Kyrtopoulos PhD) (C Herder PhD) (C Herder) (Prof J Hampe MD) (R Soong) (Prof P Vineis) (Prof M I McCarthy).

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http://dx.doi.org/10.1016/S2213-8587(15)00127-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724884PMC
July 2015

Sex hormone-binding globulin associations with circulating lipids and metabolites and the risk for type 2 diabetes: observational and causal effect estimates.

Int J Epidemiol 2015 Apr 6;44(2):623-37. Epub 2015 Jun 6.

Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland, NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland, NordLab Oulu, Oulu University Hospital and Department of Clinical Chemistry, University of Oulu, Oulu, Finland, Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland, Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere, Finland, Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, School of Medicine, Tampere, Finland, National Institute for Health and Welfare, Helsinki, Finland, Public Health Genomics Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland, Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland, Estonian Genome Center, University of Tartu, Tartu, Estonia, Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK, Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland, Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland, Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, Imperial College London, London, UK, Institute of Health Sciences & Biocenter Oulu, University of Oulu, Oulu, Finland, Unit of Primary Care, Oulu University Hospital, Oulu, Finland, Department of Children and Young People and Families, National Institute for Health and Welfare, Oulu, Finland, Computational Medicine, School of Social and Community Medicine, University of Bristol, Bristol, UK and Computational Medicine, Oulu University Hospital, Oulu, Finland. Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland, NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, F

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http://dx.doi.org/10.1093/ije/dyv093DOI Listing
April 2015

Associations of multiple lipoprotein and apolipoprotein measures with worsening of glycemia and incident type 2 diabetes in 6607 non-diabetic Finnish men.

Atherosclerosis 2015 May 23;240(1):272-7. Epub 2015 Mar 23.

Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2015.03.034DOI Listing
May 2015

Quantitative serum nuclear magnetic resonance metabolomics in cardiovascular epidemiology and genetics.

Circ Cardiovasc Genet 2015 Feb;8(1):192-206

From the Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (P.S., A.J.K., P.W., T.S., M.A.-K.); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (P.S., M.A.-K.); Oulu University Hospital, Oulu, Finland (M.A.-K.); and Computational Medicine, School of Social and Community Medicine and Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (M.A.-K.).

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https://www.ahajournals.org/doi/10.1161/CIRCGENETICS.114.000
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http://dx.doi.org/10.1161/CIRCGENETICS.114.000216DOI Listing
February 2015

Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts.

Circulation 2015 Mar 8;131(9):774-85. Epub 2015 Jan 8.

From Computational Medicine, Institute of Health Sciences, University of Oulu, Finland (P.W., P.S., T. Tynkkynen, Q.W., M.T., A.J.K., J. Kettunen, M.A.-K.); Department of Chronic Disease Prevention, National Institute for Health and Welfare, Finland (P.W., A.S.H., J. Kettunen, A.J., M.P., V.S.); Institute for Molecular Medicine Finland, University of Helsinki (P.W., A.S.H., M.P., S.P.); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio (P.S., T. Tynkkynen, Q.W., M.T., M.A.-K.); Faculty of Epidemiology and Public Health, London School of Hygiene and Tropical Medicine, United Kingdom (D.P.-M., J.-P.C.); Institute of Cardiovascular Science, University College London, United Kingdom (T. Tillin, A.D.H., J.-P.C., N.C.); Framingham Heart Study of the National Heart, Lung, and Blood Institute and Boston University School of Medicine, Framingham, MA (A.G., R.S.V.); Genome Analysis Center, Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg, Germany (A.A., J.A.); Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Finland (J. Kaikkonen, V.M., O.T.R.); Department of Food and Environmental Sciences, University of Helsinki, Finland (V.M.,); Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Finland (M.K.); Department of Clinical Chemistry, Fimlab Laboratories, and School of Medicine, University of Tampere, Finland (T.L.); Medical Research Council Integrative Epidemiology Unit at the University of Bristol, United Kingdom (D.A.L., T.R.G., M.A.-K.); School of Social and Community Medicine, University of Bristol, United Kingdom (D.A.L., T.R.G., M.A.-K.); Institute of Cardiovascular and Medical Sciences, University of Glasgow, United Kingdom (N.S.); Hannover Medical School, Hannover Unified Biobank, Germany (T.I.); Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.013116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351161PMC
March 2015

Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change.

PLoS Med 2014 Dec 9;11(12):e1001765. Epub 2014 Dec 9.

Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom; Oulu University Hospital, Oulu, Finland; Computational Medicine, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1001765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260795PMC
December 2014

Interactions between genetic variants and dietary lipid composition: effects on circulating LDL cholesterol in children.

Am J Clin Nutr 2014 Dec 8;100(6):1569-77. Epub 2014 Oct 8.

From the Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (AVA-O, NP, MKO, VM, KP, and TR); the Department of Food and Environmental Sciences (VM) and the Institute for Molecular Medicine Finland (FIMM) (JK), University of Helsinki, Helsinki, Finland; the Department of Clinical Chemistry, Fimlab Laboratories, Pirkanmaa Hospital District, School of Medicine, University of Tampere, Tampere, Finland (TL); the Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland (MK); Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland (KP); the Department of Pediatrics, Turku University Hospital, Turku, Finland (HN and OS); Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland (AJK, PS, and MA-K); NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland (PS and MA-K); Oulu University Hospital, Oulu, Finland (MA-K); Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom (MA-K); the Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland (JSV and TR); and the Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland (OTR).

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http://dx.doi.org/10.3945/ajcn.114.085027DOI Listing
December 2014

Lipoprotein subclass metabolism in nonalcoholic steatohepatitis.

J Lipid Res 2014 Dec 24;55(12):2676-84. Epub 2014 Oct 24.

Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland Clinical Nutrition and Obesity Center, Kuopio University Hospital, Kuopio, Finland.

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http://www.jlr.org/lookup/doi/10.1194/jlr.P054387
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http://dx.doi.org/10.1194/jlr.P054387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242459PMC
December 2014

A metabolic view on menopause and ageing.

Nat Commun 2014 Aug 21;5:4708. Epub 2014 Aug 21.

1] Public Health Genomics Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Biomedicum 1, Haartmaninkatu 8, Helsinki 00290, Finland [2] Institute for Molecular Medicine (FIMM), University of Helsinki, Biomedicum 2, Tukholmankatu 8, Helsinki 00290, Finland [3] Estonian Genome Center, University of Tartu, Riia 23b, Tartu 51010, Estonia.

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http://dx.doi.org/10.1038/ncomms5708DOI Listing
August 2014

Patients with type 1 diabetes show signs of vascular dysfunction in response to multiple high-fat meals.

Nutr Metab (Lond) 2014 13;11:28. Epub 2014 Jun 13.

Folkhälsan Institute of Genetics, Folkhälsan Research Center, Biomedicum, Helsinki, Finland ; Department of Medicine, Division of Nephrology, Helsinki University Central Hospital, Helsinki, Finland ; Diabetes & Obesity Research Program, Research Program's Unit, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1186/1743-7075-11-28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067102PMC
June 2014

Assessing multivariate gene-metabolome associations with rare variants using Bayesian reduced rank regression.

Bioinformatics 2014 Jul 24;30(14):2026-34. Epub 2014 Mar 24.

Department of Information and Computer Science, Helsinki Institute for Information Technology HIIT, Aalto University, Esbo, Finland, Center for Communicable Disease Dynamics, Harvard School of Public Health, Boston, MA, USA Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Unit of Public Health Genomics, National Institute for Health and Welfare, Helsinki, Computational Medicine, Institute of Health Sciences, University of Oulu and Oulu University Hospital, Oulu, NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland, Department of Epidemiology and Biostatistics, MRC Health Protection, Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College, London, UK, Institute of Health Sciences, Biocenter Oulu, University of Oulu, Oulu, Department of Clinical Physiology, Tampere University Hospital and University of Tampere, Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere School of Medicine, Tampere, Finland, Computational Medicine, School of Social and Community Medicine and the Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK, Department of Clinical Physiology and Nuclear Medicine, Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku and Turku University Hospital, Turku, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Unit of Primary Care, Oulu University Hospital, Department of Children and Young People and Families, National Institute for Health and Welfare, Oulu, Finland, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK, Hjelt Institute and Department of Computer Science, Helsinki Institute for Information Technology HIIT, University of Helsinki, Helsinki, FinlandDepartment of Information and Computer Science, Helsinki Institute for Information Technology HIIT, Aalto University, Esbo, Finland, Center for Communicable Dise

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http://dx.doi.org/10.1093/bioinformatics/btu140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080737PMC
July 2014

A comparison of anthropometric, metabolic, and reproductive characteristics of young adult women from opposite-sex and same-sex twin pairs.

Front Endocrinol (Lausanne) 2014 7;5:28. Epub 2014 Mar 7.

Department of Public Health, University of Helsinki , Helsinki , Finland ; Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare , Helsinki , Finland ; Institute for Molecular Medicine FIMM , Helsinki , Finland.

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http://dx.doi.org/10.3389/fendo.2014.00028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945783PMC
March 2014

Effects of whole grain, fish and bilberries on serum metabolic profile and lipid transfer protein activities: a randomized trial (Sysdimet).

PLoS One 2014 28;9(2):e90352. Epub 2014 Feb 28.

Department of Clinical Nutrition, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, Kuopio, Finland ; Institute of Clinical Medicine, Internal Medicine, Kuopio University Hospital, Kuopio, Finland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090352PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938672PMC
October 2014

Genome metabolome integrated network analysis to uncover connections between genetic variants and complex traits: an application to obesity.

J R Soc Interface 2014 May 26;11(94):20130908. Epub 2014 Feb 26.

Department of Epidemiology and Biostatistics, School of Public Health, MRC-HPA Centre for Environment and Health, Faculty of Medicine, Imperial College London, , London, UK.

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http://dx.doi.org/10.1098/rsif.2013.0908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973353PMC
May 2014

Association between serum fatty acids and lipoprotein subclass profile in healthy young adults: exploring common genetic and environmental factors.

Atherosclerosis 2014 Apr 21;233(2):394-402. Epub 2014 Jan 21.

Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki 00014, Finland; Population Research Unit, Department of Social Research, University of Helsinki, Helsinki 00014, Finland.

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https://linkinghub.elsevier.com/retrieve/pii/S00219150140004
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http://dx.doi.org/10.1016/j.atherosclerosis.2013.12.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826157PMC
April 2014

Effect of fatty and lean fish intake on lipoprotein subclasses in subjects with coronary heart disease: a controlled trial.

J Clin Lipidol 2014 Jan-Feb;8(1):126-33. Epub 2013 Sep 30.

Institute of Public Health and Clinical Nutrition, Kuopio Campus, University of Eastern Finland, Kuopio, Finland; Research Unit, Kuopio University Hospital, Kuopio, Finland.

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https://linkinghub.elsevier.com/retrieve/pii/S19332874130029
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http://dx.doi.org/10.1016/j.jacl.2013.09.007DOI Listing
October 2014

[Fatty fish modifies HDL particle size and lipid concentrations].

Duodecim 2013 ;129(24):2661-70

Itä-Suomen yliopisto, lääketieteen laitos, kansanterveystieteen ja kliinisen ravitsemustieteen yksikkö, KYS, tutkimusyksikkö.

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February 2014

Lipoprotein subclass profiling reveals pleiotropy in the genetic variants of lipid risk factors for coronary heart disease: a note on Mendelian randomization studies.

J Am Coll Cardiol 2013 Nov 18;62(20):1906-8. Epub 2013 Sep 18.

Computational Medicine Research Group, Institute of Health Sciences, University of Oulu, Oulu, Finland; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.jacc.2013.07.085DOI Listing
November 2013

Effects of sea buckthorn and bilberry on serum metabolites differ according to baseline metabolic profiles in overweight women: a randomized crossover trial.

Am J Clin Nutr 2013 Oct 14;98(4):941-51. Epub 2013 Aug 14.

Departments of Biochemistry and Food Chemistry and Medicine, University of Turku, Turku, Finland; Aromtech Ltd, Tornio, Finland.

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http://dx.doi.org/10.3945/ajcn.113.060590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778864PMC
October 2013

Association of height and pubertal timing with lipoprotein subclass profile: exploring the role of genetic and environmental effects.

Am J Hum Biol 2013 Jul-Aug;25(4):465-72. Epub 2013 May 4.

Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country UPV/EHU, Leioa, Spain.

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http://dx.doi.org/10.1002/ajhb.22381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834886PMC
November 2013

Lipoprotein subclass profiles in young adults born preterm at very low birth weight.

Lipids Health Dis 2013 Apr 30;12:57. Epub 2013 Apr 30.

Department of Chronic Disease Prevention, National Institute for Health and Welfare, Mannerheimintie 166, PO Box 30, FI-00271 Helsinki, Finland.

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http://dx.doi.org/10.1186/1476-511X-12-57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661387PMC
April 2013

Weight change and lipoprotein particle concentration and particle size: a cohort study with 6.5-year follow-up.

Atherosclerosis 2012 Jul 15;223(1):239-43. Epub 2012 May 15.

Institute of Public Health and Clinical Nutrition, Primary Health Care, School of Medicine, University of Eastern Finland, Kuopio, Finland.

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https://linkinghub.elsevier.com/retrieve/pii/S00219150120028
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http://dx.doi.org/10.1016/j.atherosclerosis.2012.05.005DOI Listing
July 2012

Quantitative high-throughput metabolomics: a new era in epidemiology and genetics.

Genome Med 2012 Apr 30;4(4):36. Epub 2012 Apr 30.

Computational Medicine, Institute of Clinical Medicine, Faculty of Medicine, University of Oulu, PO Box 5000, FI-90014 Oulu, Finland.

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http://dx.doi.org/10.1186/gm335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446264PMC
April 2012

Metabolic diversity of progressive kidney disease in 325 patients with type 1 diabetes (the FinnDiane Study).

J Proteome Res 2012 Mar 26;11(3):1782-90. Epub 2012 Jan 26.

Computational Medicine Research Group, Institute of Clinical Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu , Finland.

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http://dx.doi.org/10.1021/pr201036jDOI Listing
March 2012

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol.

PLoS Genet 2011 Oct 20;7(10):e1002333. Epub 2011 Oct 20.

Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1371/journal.pgen.1002333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197672PMC
October 2011

Genome-wide association studies and systems biology: together at last.

Trends Genet 2011 Dec 20;27(12):493-8. Epub 2011 Oct 20.

College of Chemistry and Chemical Engineering, Central South University, Changsha, Hunan Province, China.

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http://dx.doi.org/10.1016/j.tig.2011.09.002DOI Listing
December 2011

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.

Authors:
John C Chambers Weihua Zhang Joban Sehmi Xinzhong Li Mark N Wass Pim Van der Harst Hilma Holm Serena Sanna Maryam Kavousi Sebastian E Baumeister Lachlan J Coin Guohong Deng Christian Gieger Nancy L Heard-Costa Jouke-Jan Hottenga Brigitte Kühnel Vinod Kumar Vasiliki Lagou Liming Liang Jian'an Luan Pedro Marques Vidal Irene Mateo Leach Paul F O'Reilly John F Peden Nilufer Rahmioglu Pasi Soininen Elizabeth K Speliotes Xin Yuan Gudmar Thorleifsson Behrooz Z Alizadeh Larry D Atwood Ingrid B Borecki Morris J Brown Pimphen Charoen Francesco Cucca Debashish Das Eco J C de Geus Anna L Dixon Angela Döring Georg Ehret Gudmundur I Eyjolfsson Martin Farrall Nita G Forouhi Nele Friedrich Wolfram Goessling Daniel F Gudbjartsson Tamara B Harris Anna-Liisa Hartikainen Simon Heath Gideon M Hirschfield Albert Hofman Georg Homuth Elina Hyppönen Harry L A Janssen Toby Johnson Antti J Kangas Ido P Kema Jens P Kühn Sandra Lai Mark Lathrop Markus M Lerch Yun Li T Jake Liang Jing-Ping Lin Ruth J F Loos Nicholas G Martin Miriam F Moffatt Grant W Montgomery Patricia B Munroe Kiran Musunuru Yusuke Nakamura Christopher J O'Donnell Isleifur Olafsson Brenda W Penninx Anneli Pouta Bram P Prins Inga Prokopenko Ralf Puls Aimo Ruokonen Markku J Savolainen David Schlessinger Jeoffrey N L Schouten Udo Seedorf Srijita Sen-Chowdhry Katherine A Siminovitch Johannes H Smit Timothy D Spector Wenting Tan Tanya M Teslovich Taru Tukiainen Andre G Uitterlinden Melanie M Van der Klauw Ramachandran S Vasan Chris Wallace Henri Wallaschofski H-Erich Wichmann Gonneke Willemsen Peter Würtz Chun Xu Laura M Yerges-Armstrong Goncalo R Abecasis Kourosh R Ahmadi Dorret I Boomsma Mark Caulfield William O Cookson Cornelia M van Duijn Philippe Froguel Koichi Matsuda Mark I McCarthy Christa Meisinger Vincent Mooser Kirsi H Pietiläinen Gunter Schumann Harold Snieder Michael J E Sternberg Ronald P Stolk Howard C Thomas Unnur Thorsteinsdottir Manuela Uda Gérard Waeber Nicholas J Wareham Dawn M Waterworth Hugh Watkins John B Whitfield Jacqueline C M Witteman Bruce H R Wolffenbuttel Caroline S Fox Mika Ala-Korpela Kari Stefansson Peter Vollenweider Henry Völzke Eric E Schadt James Scott Marjo-Riitta Järvelin Paul Elliott Jaspal S Kooner

Nat Genet 2011 Oct 16;43(11):1131-8. Epub 2011 Oct 16.

Epidemiology and Biostatistics, Imperial College London, Norfolk Place, London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482372PMC
October 2011

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

Authors:
Georg B Ehret Patricia B Munroe Kenneth M Rice Murielle Bochud Andrew D Johnson Daniel I Chasman Albert V Smith Martin D Tobin Germaine C Verwoert Shih-Jen Hwang Vasyl Pihur Peter Vollenweider Paul F O'Reilly Najaf Amin Jennifer L Bragg-Gresham Alexander Teumer Nicole L Glazer Lenore Launer Jing Hua Zhao Yurii Aulchenko Simon Heath Siim Sõber Afshin Parsa Jian'an Luan Pankaj Arora Abbas Dehghan Feng Zhang Gavin Lucas Andrew A Hicks Anne U Jackson John F Peden Toshiko Tanaka Sarah H Wild Igor Rudan Wilmar Igl Yuri Milaneschi Alex N Parker Cristiano Fava John C Chambers Ervin R Fox Meena Kumari Min Jin Go Pim van der Harst Wen Hong Linda Kao Marketa Sjögren D G Vinay Myriam Alexander Yasuharu Tabara Sue Shaw-Hawkins Peter H Whincup Yongmei Liu Gang Shi Johanna Kuusisto Bamidele Tayo Mark Seielstad Xueling Sim Khanh-Dung Hoang Nguyen Terho Lehtimäki Giuseppe Matullo Ying Wu Tom R Gaunt N Charlotte Onland-Moret Matthew N Cooper Carl G P Platou Elin Org Rebecca Hardy Santosh Dahgam Jutta Palmen Veronique Vitart Peter S Braund Tatiana Kuznetsova Cuno S P M Uiterwaal Adebowale Adeyemo Walter Palmas Harry Campbell Barbara Ludwig Maciej Tomaszewski Ioanna Tzoulaki Nicholette D Palmer Thor Aspelund Melissa Garcia Yen-Pei C Chang Jeffrey R O'Connell Nanette I Steinle Diederick E Grobbee Dan E Arking Sharon L Kardia Alanna C Morrison Dena Hernandez Samer Najjar Wendy L McArdle David Hadley Morris J Brown John M Connell Aroon D Hingorani Ian N M Day Debbie A Lawlor John P Beilby Robert W Lawrence Robert Clarke Jemma C Hopewell Halit Ongen Albert W Dreisbach Yali Li J Hunter Young Joshua C Bis Mika Kähönen Jorma Viikari Linda S Adair Nanette R Lee Ming-Huei Chen Matthias Olden Cristian Pattaro Judith A Hoffman Bolton Anna Köttgen Sven Bergmann Vincent Mooser Nish Chaturvedi Timothy M Frayling Muhammad Islam Tazeen H Jafar Jeanette Erdmann Smita R Kulkarni Stefan R Bornstein Jürgen Grässler Leif Groop Benjamin F Voight Johannes Kettunen Philip Howard Andrew Taylor Simonetta Guarrera Fulvio Ricceri Valur Emilsson Andrew Plump Inês Barroso Kay-Tee Khaw Alan B Weder Steven C Hunt Yan V Sun Richard N Bergman Francis S Collins Lori L Bonnycastle Laura J Scott Heather M Stringham Leena Peltonen Markus Perola Erkki Vartiainen Stefan-Martin Brand Jan A Staessen Thomas J Wang Paul R Burton Maria Soler Artigas Yanbin Dong Harold Snieder Xiaoling Wang Haidong Zhu Kurt K Lohman Megan E Rudock Susan R Heckbert Nicholas L Smith Kerri L Wiggins Ayo Doumatey Daniel Shriner Gudrun Veldre Margus Viigimaa Sanjay Kinra Dorairaj Prabhakaran Vikal Tripathy Carl D Langefeld Annika Rosengren Dag S Thelle Anna Maria Corsi Andrew Singleton Terrence Forrester Gina Hilton Colin A McKenzie Tunde Salako Naoharu Iwai Yoshikuni Kita Toshio Ogihara Takayoshi Ohkubo Tomonori Okamura Hirotsugu Ueshima Satoshi Umemura Susana Eyheramendy Thomas Meitinger H-Erich Wichmann Yoon Shin Cho Hyung-Lae Kim Jong-Young Lee James Scott Joban S Sehmi Weihua Zhang Bo Hedblad Peter Nilsson George Davey 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Ewa Zukowska-Szczechowska Lynne E Wagenknecht F Gerald R Fowkes Fadi J Charchar Peter E H Schwarz Caroline Hayward Xiuqing Guo Charles Rotimi Michiel L Bots Eva Brand Nilesh J Samani Ozren Polasek Philippa J Talmud Fredrik Nyberg Diana Kuh Maris Laan Kristian Hveem Lyle J Palmer Yvonne T van der Schouw Juan P Casas Karen L Mohlke Paolo Vineis Olli Raitakari Santhi K Ganesh Tien Y Wong E Shyong Tai Richard S Cooper Markku Laakso Dabeeru C Rao Tamara B Harris Richard W Morris Anna F Dominiczak Mika Kivimaki Michael G Marmot Tetsuro Miki Danish Saleheen Giriraj R Chandak Josef Coresh Gerjan Navis Veikko Salomaa Bok-Ghee Han Xiaofeng Zhu Jaspal S Kooner Olle Melander Paul M Ridker Stefania Bandinelli Ulf B Gyllensten Alan F Wright James F Wilson Luigi Ferrucci Martin Farrall Jaakko Tuomilehto Peter P Pramstaller Roberto Elosua Nicole Soranzo Eric J G Sijbrands David Altshuler Ruth J F Loos Alan R Shuldiner Christian Gieger Pierre Meneton Andre G Uitterlinden Nicholas J Wareham Vilmundur Gudnason Jerome I Rotter Rainer Rettig Manuela Uda David P Strachan Jacqueline C M Witteman Anna-Liisa Hartikainen Jacques S Beckmann Eric Boerwinkle Ramachandran S Vasan Michael Boehnke Martin G Larson Marjo-Riitta Järvelin Bruce M Psaty Gonçalo R Abecasis Aravinda Chakravarti Paul Elliott Cornelia M van Duijn Christopher Newton-Cheh Daniel Levy Mark J Caulfield Toby Johnson

Evidence of how rs7575840 influences apolipoprotein B-containing lipid particles.

Arterioscler Thromb Vasc Biol 2011 May 10;31(5):1201-7. Epub 2011 Mar 10.

Department of Human Genetics, David Geffen School of Medicine at the University of California, Los Angeles, Gonda Center, Rm 6335B, 695 Charles E. Young Dr S, Los Angeles, CA 90095-7088, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081410PMC
May 2011

High serum adiponectin is associated with favorable lipoprotein subclass profile in 6.4-year follow-up.

Eur J Endocrinol 2011 Apr 11;164(4):549-52. Epub 2011 Jan 11.

Unit of General Practice, Central Finland Central Hospital, Keskussairaalantie 19, 40620 Jyväskylä, Finland.

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http://dx.doi.org/10.1530/EJE-10-1065DOI Listing
April 2011

Characterization of systemic metabolic phenotypes associated with subclinical atherosclerosis.

Mol Biosyst 2011 Feb 5;7(2):385-93. Epub 2010 Nov 5.

Computational Medicine Research Group, Institute of Clinical Medicine, University of Oulu and Biocenter Oulu, PO Box 5000, FI-90014, Oulu, Finland.

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http://dx.doi.org/10.1039/c0mb00066cDOI Listing
February 2011

High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism.

Analyst 2009 Sep 30;134(9):1781-5. Epub 2009 Jul 30.

NMR Metabonomics Laboratory, Laboratory of Chemistry, Department of Biosciences, University of Kuopio, Kuopio, Finland.

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September 2009