Antony W Burgess

Antony W Burgess

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Antony W Burgess

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Epidermal growth factor receptor: Structure-function informing the design of anticancer therapeutics.

Exp Cell Res 2018 Oct 9;371(1):1-19. Epub 2018 Aug 9.

Structural Biology Division, The Walter and Eliza Hall Institute of Medical Research, Victoria 3052, Australia; Department of Surgery, The University of Melbourne, The Royal Melbourne Hospital, Parkville, Victoria 3050, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2018.08.009DOI Listing
October 2018

Colorectal Cancer Cell Line Proteomes Are Representative of Primary Tumors and Predict Drug Sensitivity.

Gastroenterology 2017 10 16;153(4):1082-1095. Epub 2017 Jun 16.

Systems Biology and Personalised Medicine Division, The Walter and Eliza Hall Institute of Medial Research, Parkville, VIC, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia; Department of Surgery, The University of Melbourne, Parkville, VIC, Australia; School of Biomedical Sciences, Monash University, Clayton, VIC, Australia. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623120PMC
October 2017

Evolution of anti-HER2 therapies for cancer treatment.

Cancer Treat Rev 2017 Sep 6;59:1-21. Epub 2017 Jul 6.

Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia; School of Cancer Medicine, La Trobe University, Melbourne, Australia; Department of Molecular Imaging and Therapy, Austin Health, Melbourne, Australia; Department of Medicine, University of Melbourne, Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2017.06.005DOI Listing
September 2017

TGF-β and IL-6 family signalling crosstalk: an integrated model.

Growth Factors 2017 06;35(2-3):100-124

b Structural Biology Division, The Walter and Eliza Hall Institute of Medical Research (WEHI) , Parkville , VIC , Australia.

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https://www.tandfonline.com/doi/full/10.1080/08977194.2017.1
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http://dx.doi.org/10.1080/08977194.2017.1363746DOI Listing
June 2017

Bispecific protein targets prostate cancer.

Authors:
Antony W Burgess

Oncotarget 2017 May;8(22):35484-35485

Walter and Eliza Hall Institute, Parkville, Australia.

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http://dx.doi.org/10.18632/oncotarget.17372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482589PMC
May 2017

Mathematical model of TGF-βsignalling: feedback coupling is consistent with signal switching.

BMC Syst Biol 2017 04 13;11(1):48. Epub 2017 Apr 13.

Department of Surgery (RMH), The University of Melbourne, Parkville, Victoria, 3050, Australia.

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http://bmcsystbiol.biomedcentral.com/articles/10.1186/s12918
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http://dx.doi.org/10.1186/s12918-017-0421-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390422PMC
April 2017

Synthesis of an inositol hexakisphosphate (IP6) affinity probe to study the interactome from a colon cancer cell line.

Integr Biol (Camb) 2016 Mar;8(3):309-18

Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia. and Department of Medical Biology, University of Melbourne, Parkville, Victoria 3052, Australia and Department of Surgery, RMH, University of Melbourne, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1039/c5ib00264hDOI Listing
March 2016

Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells.

Genom Data 2016 Mar 3;7:293-6. Epub 2016 Feb 3.

Structural Biology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia; Tumour Biology Branch, Ludwig Institute for Cancer Research, Parkville, Victoria, Australia; Department Surgery, RMH, University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1016/j.gdata.2016.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778681PMC
March 2016

Discrete Element Framework for Modelling Extracellular Matrix, Deformable Cells and Subcellular Components.

PLoS Comput Biol 2015 Oct 9;11(10):e1004544. Epub 2015 Oct 9.

Engineering Computational Biology, School of Computer Science and Software Engineering, The University of Western Australia, Perth, Australia.

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http://dx.doi.org/10.1371/journal.pcbi.1004544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599884PMC
October 2015

Glycoprotein A33 deficiency: a new mouse model of impaired intestinal epithelial barrier function and inflammatory disease.

Dis Model Mech 2015 Aug 8;8(8):805-15. Epub 2015 May 8.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia Department of Medical Biology, University of Melbourne, Parkville, Victoria 3052, Australia Ludwig Institute for Cancer Research, Melbourne-Parkville Branch, Parkville, Victoria 3050, Australia

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http://dx.doi.org/10.1242/dmm.019935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527289PMC
August 2015

Analysis of Wnt signalling dynamics during colon crypt development in 3D culture.

Sci Rep 2015 Jun 18;5:11036. Epub 2015 Jun 18.

1] Structural Biology Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052 Australia [2] Department of Medical Biology, University of Melbourne, 1G Royal Parade, Parkville, VIC 3052 Australia [3] Department of Surgery, University of Melbourne, Royal Melbourne Hospital, Parkville, VIC 3050, Australia.

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http://dx.doi.org/10.1038/srep11036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471889PMC
June 2015

Notch ligand delta-like1: X-ray crystal structure and binding affinity.

Biochem J 2015 May;468(1):159-66

*Department of Structural Biology, Walter and Eliza Hall Institute of Medical Research and Department of Medical Biology, University of Melbourne, Parkville, 3052 Australia.

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http://dx.doi.org/10.1042/BJ20150010DOI Listing
May 2015

LRIG1 extracellular domain: structure and function analysis.

J Mol Biol 2015 May 9;427(10):1934-48. Epub 2015 Mar 9.

Structural Biology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, Victoria 3010, Australia; Department of Surgery, RMH, University of Melbourne, Parkville, Victoria 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2015.03.001DOI Listing
May 2015

Colon cryptogenesis: asymmetric budding.

PLoS One 2013 21;8(10):e78519. Epub 2013 Oct 21.

The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia ; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia ; Ludwig Institute for Cancer Research, Melbourne-Parkville Branch, Parkville, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078519PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804607PMC
February 2015

Dual role of Src kinase in governing neuronal survival.

Brain Res 2015 Jan 31;1594:1-14. Epub 2014 Oct 31.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville 3010, VIC, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2014.10.040DOI Listing
January 2015

Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration.

Sci Signal 2014 Sep 30;7(345):ra92. Epub 2014 Sep 30.

Ludwig Institute for Cancer Research, Melbourne, Victoria 3052, Australia. Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria 3052, Australia. Department of Medical Biology, University of Melbourne, Melbourne, Victoria 3052, Australia.

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http://dx.doi.org/10.1126/scisignal.2005411DOI Listing
September 2014

Quantitative intratumoural microdistribution and kinetics of (131)I-huA33 antibody in patients with colorectal carcinoma.

EJNMMI Res 2014 30;4:22. Epub 2014 May 30.

Ludwig Institute for Cancer Research, Austin Health, Melbourne 3084, Australia ; Department of Nuclear Medicine and Centre for PET, Austin Health, Melbourne 3084, Australia.

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http://www.ejnmmires.com/content/4/1/22
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http://dx.doi.org/10.1186/s13550-014-0022-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070025PMC
July 2014

Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.

Cancer Res 2014 Jun 22;74(12):3238-47. Epub 2014 Apr 22.

Authors' Affiliations: Ludwig Institute for Cancer Research; Systems Biology and Personalised Medicine Division; Structural Biology Division; Walter and Eliza Hall Institute of Medical Research; Faculty of Medicine, Dentistry and Health Sciences, Department of Medical Biology, University of Melbourne, Parkville; VLSCI Life Sciences Computation Centre, a collaboration between Melbourne, Monash and LaTrobe Universities, c/o The University of Melbourne, Carlton; Oncogenic Transcription Laboratory, Ludwig Institute for Cancer Research, Austin, VIC, Australia; Cancer and Population Studies Group, Queensland Institute of Medical Research, Herston, QLD, Australia; Group of Molecular Oncology, CIBBIM-Nanomedicine, Vall d'Hebron University Hospital, Research Institute (VHIR), Universitat Autònoma de Barcelona, Passeig Vall d'Hebron, 119-129, 08035 Barcelona; CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN); Spain; Ludwig Collaborative Laboratory for Cancer Biology and Therapy, Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; Ludwig Institute for Cancer Research Ltd., New York, New York; Cancer and Immunogenetics Laboratory, Weatherall Institute of Molecular Medicine (WIMM), John Radcliffe Hospital, University of Oxford; and Molecular and Population Genetics Laboratory, Wellcome Trust Centre for Human Genetics, Oxford, United KingdomAuthors' Affiliations: Ludwig Institute for Cancer Research; Systems Biology and Personalised Medicine Division; Structural Biology Division; Walter and Eliza Hall Institute of Medical Research; Faculty of Medicine, Dentistry and Health Sciences, Department of Medical Biology, University of Melbourne, Parkville; VLSCI Life Sciences Computation Centre, a collaboration between Melbourne, Monash and LaTrobe Universities, c/o The University of Melbourne, Carlton; Oncogenic Transcription Laboratory, Ludwig Institute for Cancer Research, Austin, VIC, Australia; Cancer and Population Studies

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http://dx.doi.org/10.1158/0008-5472.CAN-14-0013DOI Listing
June 2014

Structure and function of LGR5: an enigmatic G-protein coupled receptor marking stem cells.

Protein Sci 2014 May 19;23(5):551-65. Epub 2014 Mar 19.

Structural Biology Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria, 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, Victoria, 3052, Australia.

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http://dx.doi.org/10.1002/pro.2446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005707PMC
May 2014

Cell organisation in the colonic crypt: a theoretical comparison of the pedigree and niche concepts.

PLoS One 2013 12;8(9):e73204. Epub 2013 Sep 12.

School of Computer Science and Software Engineering, University of Western Australia, Perth, Western Australia, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0073204PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771985PMC
April 2014

Colonic myofibroblast cell line stimulates colonoid formation.

Am J Physiol Gastrointest Liver Physiol 2014 Apr 30;306(7):G547-56. Epub 2014 Jan 30.

The Walter and Eliza Hall Institute of Medical Research, Melbourne;

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http://dx.doi.org/10.1152/ajpgi.00267.2013DOI Listing
April 2014

EGF receptor family: twisting targets for improved cancer therapies.

Growth Factors 2014 Apr 18;32(2):74-81. Epub 2014 Mar 18.

The Walter & Eliza Hall Institute of Medical Research, Burgess Lab Structural Biology , Parkville , Australia .

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http://dx.doi.org/10.3109/08977194.2014.896355DOI Listing
April 2014

Recruitment of the adaptor protein Grb2 to EGFR tetramers.

Biochemistry 2014 Apr 21;53(16):2594-604. Epub 2014 Apr 21.

Centre for Micro-Photonics, Faculty of Engineering and Industrial Sciences, Swinburne University of Technology , Hawthorn, Victoria 3122, Australia.

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http://dx.doi.org/10.1021/bi500182xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010257PMC
April 2014

Analysis of Wnt signaling β-catenin spatial dynamics in HEK293T cells.

BMC Syst Biol 2014 Apr 8;8:44. Epub 2014 Apr 8.

Structural Biology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.

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http://dx.doi.org/10.1186/1752-0509-8-44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108056PMC
April 2014

Chain-specific antibodies for laminin-511.

Growth Factors 2013 Dec;31(6):209-19

The Ludwig Institute for Cancer Research, Melbourne Branch , Parkville, Victoria , Australia .

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http://dx.doi.org/10.3109/08977194.2013.859684DOI Listing
December 2013

Immunopurification of adenomatous polyposis coli (APC) proteins.

BMC Res Notes 2013 Oct 25;6:429. Epub 2013 Oct 25.

Ludwig Institute for Cancer Research-Parkville branch, Parkville, VIC 3050, Australia.

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http://dx.doi.org/10.1186/1756-0500-6-429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015550PMC
October 2013

Exploring higher-order EGFR oligomerisation and phosphorylation--a combined experimental and theoretical approach.

Mol Biosyst 2013 Jul 30;9(7):1849-63. Epub 2013 Apr 30.

Centre for Micro-Photonics, Faculty of Engineering and Industrial Sciences, Cell Biophysics Laboratory, Swinburne University of Technology, PO Box 218, Hawthorn, Victoria 3122, Australia.

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http://dx.doi.org/10.1039/c3mb70073aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698845PMC
July 2013

The PI(3)P interactome from a colon cancer cell.

J Proteomics 2013 Apr 15;82:35-51. Epub 2013 Feb 15.

Ludwig Institute for Cancer Research, Melbourne-Parkville Branch, Post Office Box 2008 Royal Melbourne Hospital, Victoria 3050, Australia.

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http://dx.doi.org/10.1016/j.jprot.2013.01.031DOI Listing
April 2013

A high-affinity ErbB4Fc fusion protein is a potent antagonist of heregulin-mediated receptor activation.

Growth Factors 2012 Oct 2;30(5):310-9. Epub 2012 Aug 2.

CSIRO Division of Materials Science and Engineering, 343 Royal Parade, Parkville, VIC 3052, Australia.

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http://dx.doi.org/10.3109/08977194.2012.709516DOI Listing
October 2012

Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.

Electrophoresis 2012 Jul;33(12):1873-80

Joint Proteomics Research Laboratory, Ludwig Institute for Cancer Research and The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1002/elps.201100687DOI Listing
July 2012

Wnt signalling pathway parameters for mammalian cells.

PLoS One 2012 21;7(2):e31882. Epub 2012 Feb 21.

Ludwig Institute for Cancer Research, Melbourne-Parkville Branch, Parkville, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0031882PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283727PMC
June 2012

Evidence for extended YFP-EGFR dimers in the absence of ligand on the surface of living cells.

Phys Biol 2011 Dec 26;8(6):066002. Epub 2011 Sep 26.

Centre for Microphotonics, Swinburne University of Technology, Victoria, Australia.

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http://stacks.iop.org/1478-3975/8/i=6/a=066002?key=crossref.
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http://dx.doi.org/10.1088/1478-3975/8/6/066002DOI Listing
December 2011

Wnt signaling and colon tumorigenesis--a view from the periphery.

Exp Cell Res 2011 Nov 22;317(19):2748-58. Epub 2011 Aug 22.

Parkville Branch, Ludwig Institute for Cancer Research, Melbourne, 3050, Australia.

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http://dx.doi.org/10.1016/j.yexcr.2011.08.010DOI Listing
November 2011

Use of multiple reaction monitoring for multiplex analysis of colorectal cancer-associated proteins in human feces.

Electrophoresis 2011 Aug 3;32(15):1926-38. Epub 2011 May 3.

Ludwig Institute for Cancer Research, Melbourne Tumour Biology Branch, Melbourne, Victoria, Australia.

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http://doi.wiley.com/10.1002/elps.201000502
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http://dx.doi.org/10.1002/elps.201000502DOI Listing
August 2011

Conformational dynamics in a truncated epidermal growth factor receptor ectodomain.

Biochemistry 2011 Jun 18;50(23):5130-9. Epub 2011 May 18.

Swinburne University of Technology , Victoria 3122, Australia.

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http://dx.doi.org/10.1021/bi200095wDOI Listing
June 2011

Differential and synergistic effects of epidermal growth factor receptor antibodies on unliganded ErbB dimers and oligomers.

Biochemistry 2011 May 15;50(18):3581-90. Epub 2011 Apr 15.

Ludwig Institute for Cancer Research, Melbourne-Parkville Branch, Royal Melbourne Hospital, Victoria 3050, Australia.

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http://dx.doi.org/10.1021/bi101785hDOI Listing
May 2011

Analysis of cellular phosphatidylinositol (3,4,5)-trisphosphate levels and distribution using confocal fluorescent microscopy.

Anal Biochem 2010 Nov 25;406(1):41-50. Epub 2010 Jun 25.

Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Parkville, Victsoria, Australia.

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http://dx.doi.org/10.1016/j.ab.2010.06.033DOI Listing
November 2010

Murine fecal proteomics: a model system for the detection of potential biomarkers for colorectal cancer.

J Chromatogr A 2010 May 8;1217(19):3330-40. Epub 2009 Oct 8.

Ludwig Institute for Cancer Research, Melbourne Tumour Biology Branch, PO Box 2008, Royal Melbourne Hospital, Australia.

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http://dx.doi.org/10.1016/j.chroma.2009.10.007DOI Listing
May 2010

Incentives: encouraging adventurous ideas.

Science 2010 Jan;327(5962):145

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http://dx.doi.org/10.1126/science.327.5962.145-aDOI Listing
January 2010

Selective inhibition of proliferation in colorectal carcinoma cell lines expressing mutant APC or activated B-Raf.

Int J Cancer 2009 Jul;125(2):297-307

Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Centre for Medical Research, Victoria, Australia.

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http://dx.doi.org/10.1002/ijc.24289DOI Listing
July 2009

PI(3,4,5)P3 Interactome.

J Proteome Res 2009 Jul;8(7):3712-26

Ludwig Institute for Cancer Research, Melbourne Tumour Biology Branch, Royal Melbourne Hospital, and School of Chemistry, Bio21 Institute, University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1021/pr900320aDOI Listing
July 2009

Predominance of activated EGFR higher-order oligomers on the cell surface.

Growth Factors 2008 Dec;26(6):316-24

Ludwig Institute for Cancer Research, Melbourne Tumour Biology Branch, Royal Melbourne Hospital, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1080/08977190802442187DOI Listing
December 2008

The PI(3,5)P2 and PI(4,5)P2 interactomes.

J Proteome Res 2008 Dec;7(12):5295-313

Ludwig Institute for Cancer Research, Melbourne Tumour Biology Branch, Royal Melbourne Hospital, Parkville Victoria 3052, Australia.

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December 2008

EGFR family: structure physiology signalling and therapeutic targets.

Authors:
Antony W Burgess

Growth Factors 2008 Oct;26(5):263-74

Ludwig Institute for cancer Research, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1080/08977190802312844DOI Listing
October 2008

IL6/sIL6R complex contributes to emergency granulopoietic responses in G-CSF- and GM-CSF-deficient mice.

Blood 2008 Apr 21;111(8):3978-85. Epub 2007 Dec 21.

Ludwig Institute for Cancer Research, Melbourne Tumor Biology Branch, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1182/blood-2007-10-119636DOI Listing
April 2008

Macrophage-colony stimulating factor is required for the production of neutrophil-promoting activity by mouse embryo fibroblasts deficient in G-CSF and GM-CSF.

J Leukoc Biol 2007 Oct 25;82(4):915-25. Epub 2007 Jul 25.

Ludwig Institute for Cancer Research, Melbourne Tumor Biology Branch, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1189/jlb.0107023DOI Listing
October 2007

De novo design of beta-helical polypeptides.

Growth Factors 2007 Jun;25(3):168-90

Ludwig Institute for Cancer Research, Tumor Biology Branch, Melbourne, Australia.

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http://dx.doi.org/10.1080/08977190701679772DOI Listing
June 2007

Mice lacking three myeloid colony-stimulating factors (G-CSF, GM-CSF, and M-CSF) still produce macrophages and granulocytes and mount an inflammatory response in a sterile model of peritonitis.

J Immunol 2007 May;178(10):6435-43

Signal Transduction Laboratory, Ludwig Institute for Cancer Research, Melbourne Tumour Biology Branch, Royal Melbourne Hospital, Victoria, and Department of Medicine, University of Melbourne, Parkville, Australia.

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May 2007

The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor AG1478 increases the formation of inactive untethered EGFR dimers. Implications for combination therapy with monoclonal antibody 806.

J Biol Chem 2007 Feb 8;282(5):2840-50. Epub 2006 Nov 8.

Oncogenic Signalling Laboratory, Ludwig Institute of Cancer Research, Austin Hospital, Level 6, Harold Stokes Building, Studley Road, Heidelberg, Victoria 3084, Australia.

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http://dx.doi.org/10.1074/jbc.M605136200DOI Listing
February 2007

Identification of a novel EGF-sensitive cell cycle checkpoint.

Exp Cell Res 2007 Feb 10;313(3):511-26. Epub 2006 Nov 10.

Ludwig Institute for Cancer Research, P.O Royal Melbourne Hospital, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1016/j.yexcr.2006.10.026DOI Listing
February 2007

In situ phosphorylation of immobilized receptors on biosensor surfaces: application to E-cadherin/beta-catenin interactions.

Anal Biochem 2006 Oct 11;357(2):277-88. Epub 2006 Aug 11.

Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Parkville, Vic. 3052, Australia.

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http://dx.doi.org/10.1016/j.ab.2006.07.034DOI Listing
October 2006

Designing amino acid residues with single-conformations.

Protein Eng Des Sel 2006 Sep 24;19(9):401-8. Epub 2006 Jun 24.

Ludwig Institute for Cancer Research and Cooperative Research Centre for Cellular and Growth Factors, Melbourne, Victoria 3050, Australia.

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http://dx.doi.org/10.1093/protein/gzl024DOI Listing
September 2006

Purification and characterization of a high specificity polyclonal antibody to the adenomatous polyposis coli tumour suppressor protein.

Biomed Chromatogr 2006 Jun-Jul;20(6-7):569-75

Ludwig Institute for Cancer Research, PO Royal Melbourne Hospital, Parkville, Victoria, Australia.

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http://doi.wiley.com/10.1002/bmc.648
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http://dx.doi.org/10.1002/bmc.648DOI Listing
August 2006

Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis.

J Biol Chem 2005 Aug 30;280(34):30392-9. Epub 2005 Jun 30.

Ludwig Institute for Cancer Research, Melbourne Tumour Biology Branch, Royal Melbourne Hospital, Victoria 3050, Australia.

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http://dx.doi.org/10.1074/jbc.M504770200DOI Listing
August 2005

Fluorescence and analytical ultracentrifugation analyses of the interaction of the tyrosine kinase inhibitor, tyrphostin AG 1478-mesylate, with albumin.

Anal Biochem 2005 Jul;342(2):292-9

Ludwig Institute for Cancer Research, Melbourne Tumour Biology Branch, P.O. Royal Melbourne Hospital, Parkville, Vic. 3050, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S000326970500297
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http://dx.doi.org/10.1016/j.ab.2005.04.002DOI Listing
July 2005

The antitumor monoclonal antibody 806 recognizes a high-mannose form of the EGF receptor that reaches the cell surface when cells over-express the receptor.

FASEB J 2005 May 17;19(7):780-2. Epub 2005 Mar 17.

Ludwig Institute for Cancer Research, Tumour Targeting Program, Austin Hospital, Heidelberg, Australia.

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http://dx.doi.org/10.1096/fj.04-1766fjeDOI Listing
May 2005

The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR.

Oncogene 2004 Aug;23(36):6095-104

Tumour Targeting Program, Ludwig Institute for Cancer Research, Melbourne Branch, Austin Hospital, Heidelberg 3084, Australia.

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http://dx.doi.org/10.1038/sj.onc.1207870DOI Listing
August 2004

Restoration of full-length adenomatous polyposis coli (APC) protein in a colon cancer cell line enhances cell adhesion.

J Cell Sci 2004 Jan 16;117(Pt 3):427-39. Epub 2003 Dec 16.

Ludwig Institute for Cancer Research, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1242/jcs.00862DOI Listing
January 2004

An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors.

Mol Cell 2003 Sep;12(3):541-52

Cooperative Research Centre for Cellular Growth Factors, P.O. Box 2008, Royal Melbourne Hospital, Parkville, Victoria 3050, Australia.

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September 2003

Epidermal growth factor receptor: mechanisms of activation and signalling.

Exp Cell Res 2003 Mar;284(1):31-53

Ludwig Institute for Cancer Research, Parkville, Victoria, Australia.

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March 2003

Epidermal growth factor receptor: association of extracellular domain negatively regulates intracellular kinase activation in the absence of ligand.

Growth Factors 2003 Mar;21(1):15-30

Ludwig Institute for Cancer Research, Post Office, Royal Melbourne Hospital, Victoria 3050, Australia.

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March 2003

The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors.

Mol Cell 2003 Feb;11(2):495-505

Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, 3050, Parkville, Victoria, Australia.

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February 2003

Cytokine enhancement of in vitro antibody-dependent cellular cytotoxicity mediated by chimeric anti-GD3 monoclonal antibody KM871.

Cancer Immun 2002 Oct 7;2:13. Epub 2002 Oct 7.

Ludwig Institute for Cancer Research, Melbourne Tumour Biology Branch, Austin and Repatriation Medical Centre, Heidelberg, Victoria, 3084, Australia.

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October 2002

Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies.

J Immunol 2002 Jul;169(2):1102-9

Immunology Department, School of Basic Medical Science, Peking University Health Science Center, Beijing, China.

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July 2002

Modeling the epidermal growth factor -- epidermal growth factor receptor l2 domain interaction: implications for the ligand binding process.

J Biomol Struct Dyn 2002 Jun;19(6):961-72

The Ludwig Institute for Cancer Research, Post Office Box 2008, Royal Melbourne Hospital, Parkville, Victoria, 3050, Australia.

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http://www.tandfonline.com/doi/full/10.1080/07391102.2002.10
Publisher Site
http://dx.doi.org/10.1080/07391102.2002.10506800DOI Listing
June 2002

Effects of thioamide substitutions on the conformation and stability of alpha- and 3(10)-helices.

J Am Chem Soc 2002 May;124(18):5222-30

Ludwig Institute for Cancer Research and Cooperative Research Centre for Cellular and Growth Factors, Melbourne, Victoria, 3050, Australia.

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May 2002