Publications by authors named "Antonio Perciaccante"

85 Publications

Pietro Perugino's atopic facial dermatitis.

J Cosmet Dermatol 2021 Feb 24. Epub 2021 Feb 24.

Société Française des Sciences Humaines sur la Peau (SFSHP), Maison de la Dermatologie, Paris, France.

Pietro Vannucci (ca. 1450 - 1523), better known as Pietro Perugino, was one of the most brilliant Italian Renaissance painter working in Rome, Florence, and Perugia. The sense of spaciousness and the compositional clarity of his painting anticipated the ideals of High Renaissance [1].
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http://dx.doi.org/10.1111/jocd.14021DOI Listing
February 2021

Metastatic Carcinoma with Associated Lymphoadenopathy and Acquired Horner's Syndrome Portrayed in a Third Century CE Roman Bust.

Head Neck Pathol 2020 Nov 23. Epub 2020 Nov 23.

Institute of Pathology, Academic Clinic Munich-Bogenhausen, Englschalkingerstr. 77, 81925, Munich, Germany.

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http://dx.doi.org/10.1007/s12105-020-01252-xDOI Listing
November 2020

Heart rhythm disturbance could have caused Charles Dickens's recurrent strokes: A new medical hypothesis.

J Stroke Cerebrovasc Dis 2020 Dec 11;29(12):105289. Epub 2020 Sep 11.

Université Paris-Saclay, UVSQ (EA "LAAB" - Laboratoire Anthropologie Archéologie Biologie), UFR des Sciences de la Santé 2 avenue de la source de la Bièvre, 78180 Montigny-le-Bretonneux; Direction, Département de la Recherche et de l'Enseignement Musée du quai Branly - Jacques Chirac 222 rue de l'Université, 75007 Paris, France.

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2020.105289DOI Listing
December 2020

Beethoven: His Hearing Loss and His Hearing Aids.

Otol Neurotol 2020 Oct;41(9):1305-1308

The Hearing Aid Museum, Lynden, Washington, USA.

: To celebrate the 250th anniversary of the birth of the great classical composer, Ludwig van Beethoven (1770-1827), we point out how his hearing loss affected him and how the primitive hearing aids at that time helped mitigate his hearing loss. From the age of 26, Beethoven began to suffer from a fluctuating, progressive hearing loss ("my hearing grew worse and worse"), This started in his left ear ("in my left ear, with which this illness of my ears had started"), where he had difficulty hearing higher pitched tones ("I don't hear the high notes of the instruments and voices") and words ("Sometimes, I cannot hear people who speak quietly, I can hear the sounds, but not the words") and associated with tinnitus ("my ears, they still keep buzzing and humming day and night") and loudness recruitment ("if someone yells, it is unbearable to me").However, in spite of his hearing loss, Beethoven never lost his love for music and continued composing music, at times using some of the acoustic hearing aids that were just being developed. We analyze and describe the ear trumpets, and the resonant plate that engineer Johan Nepomuk Maelzel and piano-maker Conrad Graf, respectively, constructed to try to improve Beethoven's hearing. Moreover, we discuss the possible use of a wooden drumstick Beethoven might have used to improve his perception of the piano's sound.
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http://dx.doi.org/10.1097/MAO.0000000000002755DOI Listing
October 2020

A case of congenital Horner syndrome from the 16th century.

Lancet Neurol 2020 08;19(8):646-647

Institute of Pathology, Academic Clinic Munich-Bogenhausen, Munich, Germany.

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http://dx.doi.org/10.1016/S1474-4422(20)30214-3DOI Listing
August 2020

Pulmonary Echinococcosis in the Terminal Disease of Ferdinand II de' Medici (1610-1670).

Chest 2020 Jul 2;158(1):53-54. Epub 2020 Jul 2.

Institut für Pathologie, Klinikum München-Bogenhausen und München-Schwabing, München, Germany.

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http://dx.doi.org/10.1016/j.chest.2020.01.054DOI Listing
July 2020

Craniosynostosis in a Painting by Hans Suess Kulmbach.

J Craniofac Surg 2020 09;31(6):1510

Department of dermatology, allergology and venereology, Helsinki University Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1097/SCS.0000000000006583DOI Listing
September 2020

Corrigendum to "Has Saint Anthony of Padua suffered from congestive heart failure?" International Journal of Cardiology. 2016;221: 110-111.

Int J Cardiol 2020 Dec 10;321:130. Epub 2020 Jun 10.

Department of Public Health and Pediatric Sciences, Legal Medicine Section, University of Turin, Italy; UMR 7268, Laboratoire d'Anthropologie bio-culturelle, Droit, Etique & Santé (Adés), Faculté de Médecine de Marseille, France.

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http://dx.doi.org/10.1016/j.ijcard.2020.05.082DOI Listing
December 2020

Why paleomedicine is useful for medical education.

Postgrad Med J 2021 Feb 13;97(1144):75-76. Epub 2020 May 13.

Legal Medicine Section, Department of Public Health and Paediatric Sciences, University of Turin, Turin, Italy.

What is the place of medico-historical cases in the professional practice of the disciplinary field of medicine and biology? How can these patients from the past be used for teaching and continuing medical education? How to justify their place in biomedical publications? In this article, we explain all the legitimacy of paleomedicine, and the need to intensify such research in the form of a well-individualised branch of paleopathology and the history of medicine.
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http://dx.doi.org/10.1136/postgradmedj-2020-137804DOI Listing
February 2021

Cardiovascular Considerations in Treating Patients With Coronavirus Disease 2019 (COVID-19).

J Cardiovasc Pharmacol 2020 05;75(5):359-367

Division of Cardiology, Department of Internal Medicine, Pauley Heart Center, Virginia Commonwealth University, Richmond, VA.

A novel betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread rapidly across the globe since December 2019. Coronavirus disease 2019 (COVID-19) has a significantly higher mortality rate than seasonal influenza and has disproportionately affected older adults, especially those with cardiovascular disease and related risk factors. Adverse cardiovascular sequelae, such as myocarditis, acute myocardial infarction, and heart failure, have been reported in patients with COVID-19. No established treatment is currently available; however, several therapies, including remdesivir, hydroxychloroquine and chloroquine, and interleukin (IL)-6 inhibitors, are being used off-label and evaluated in ongoing clinical trials. Considering these therapies are not familiar to cardiovascular clinicians managing these patients, this review describes the pharmacology of these therapies in the context of their use in patients with cardiovascular-related conditions.
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http://dx.doi.org/10.1097/FJC.0000000000000836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219860PMC
May 2020

Tudor military surgery and the management of Sir Martin Frobisher's gunshot wound: Comparison with current treatment.

Injury 2020 Mar 1;51(3):597-601. Epub 2020 Feb 1.

Norwich Medical School, University of East Anglia, Norwich, Norfolk, UK. Electronic address:

Sir Martin Frobisher (ca 1535-1594), the famous Elizabethan explorer and privateer, sustained a bullet to the outer plate of his ilium from a low-velocity bullet wound fired at close range from an arquebus, an early form of musket. The bullet was removed, but he subsequently died from gas gangrene. This paper looks at the management of this injury in Tudor times and compares it to current practice. The arrival of gunpowder and the seriousness of the resulting injuries spurred innovation in surgical practice, such that at the time of Frobisher's death, the Tudor military surgeon had considerable expertise and skill. The wound, treated properly, was not serious, but his first surgeon failed to remove the wadding that the bullet took with it. This was recognised as an error at the time. A Tudor surgeon today would note that the surgical management has not really changed since their time, even though they did not understand infection and bacterial contamination. Guidelines on managing gunshot wounds, and most research, is focussed on high-velocity injuries where removal of foreign material (clothing) is mentioned. Low-velocity injuries are treated as "outpatients" and the importance of removing foreign material, especially when the bullet is left in situ, is not mentioned. The inexperienced surgeon of today risks making the same error as Frobisher's surgeon.
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http://dx.doi.org/10.1016/j.injury.2020.01.046DOI Listing
March 2020

The Silent Symphony of Ludwig van Beethoven (1770-1827).

Am J Med 2020 06 2;133(6):768. Epub 2020 Feb 2.

Azienda Sanitaria Universitaria Giuliano-Isontina, Distretto Alto Isontino, Gorizia, Italy.

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http://dx.doi.org/10.1016/j.amjmed.2019.12.047DOI Listing
June 2020

A Brief History of the Clitoris.

Arch Sex Behav 2020 01 21;49(1):47-48. Epub 2020 Jan 21.

Department of Medicine, "San Giovanni di Dio" Hospital, via Fatebenefratelli, 34, 34170, Gorzia, Italy.

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http://dx.doi.org/10.1007/s10508-020-01638-6DOI Listing
January 2020

Aeschylus' Legendary Head Trauma: Reflections on Pseudopathology and the Origins of Mythology.

J Craniofac Surg 2020 Jan/Feb;31(1):30-31

Warwick Medical School, Microbiology and Infection Unit, The University of Warwick, Warwick, United Kingdom.

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http://dx.doi.org/10.1097/SCS.0000000000006211DOI Listing
December 2019

Mid-19th century Chinese medical portraits depict late-stage female breast tumours.

Lancet Oncol 2019 10 30;20(10):1347-1348. Epub 2019 Sep 30.

Legal Medicine Section, Department of Public Health and Paediatric Sciences, University of Turin, Torino, Italy; Warwick Medical School, Biomedical Sciences, University of Warwick, Coventry, UK; UMR 7268, Laboratoire d'Anthropologie bio-culturelle, Droit, Etique & Santé (Adés), Faculté de Médecine de Marseille, Marseille, France.

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http://dx.doi.org/10.1016/S1470-2045(19)30591-1DOI Listing
October 2019

Clues to Medieval Cardiorespiratory Physiology in the Divine Comedy.

Chest 2019 09;156(3):637-639

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1016/j.chest.2019.04.129DOI Listing
September 2019

Exploring Disease Representation in Movies.

J Gen Intern Med 2019 11;34(11):2351-2354

Legal Medicine Section, Department of Public Health and Paediatric Sciences, University of Turin, Turin, Italy.

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http://dx.doi.org/10.1007/s11606-019-05254-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848425PMC
November 2019

Reply.

J Vasc Surg 2019 08;70(2):657-659

Archaeology, College of Humanities, Arts and Social Sciences, Flinders University, Adelaide, Australia.

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http://dx.doi.org/10.1016/j.jvs.2019.03.042DOI Listing
August 2019

Pope Francis' last dilemma: To kiss or not to kiss the Piscatory Ring?

Am J Infect Control 2019 09 9;47(9):1160. Epub 2019 Jul 9.

Musée du Quai Branly-Jacques Chirac, Paris, France; UVSQ, Laboratoire DANTE EA4498, Montigny-Le-Bretonneux, France.

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http://dx.doi.org/10.1016/j.ajic.2019.05.027DOI Listing
September 2019

Vincenzo Tiberio (1869-1915) and the dawn of the antibiotic age.

Intern Emerg Med 2019 11 1;14(8):1363-1364. Epub 2019 Jun 1.

Warwick Medical School, Microbiology and Infection Unit, The University of Warwick, Coventry, UK.

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http://dx.doi.org/10.1007/s11739-019-02116-1DOI Listing
November 2019

Hydrocephalus of King Charles II of Spain, the Bewitched King.

Eur Neurol 2019 21;81(1-2):76-78. Epub 2019 May 21.

Department of Ophthalmology, "Grigore. T. Popa" University of Medicine and Pharmacy, Iasi, Romania.

King of the Spanish Habsburg dynasty and sovereign of the overseas Spanish Empire, Charles II of Spain, was physically disabled, disfigured, mentally retarded, and he proved impotent. He is known in history as El Hechizado (the Bewitched) because both him and the people believed that his mental and physical incapacity were due to a "witchcraft act." Although several authors speculated about different diseases, most of them genetic such as pituitary hormone deficiency, distal renal tubular acidosis, Klinefelter syndrome, fragile X syndrome, or male XX hermaphroditism, the hypothesis of hydrocephalus was not taken into account. We don't have clear elements to hypothesize a certain etiology of Charles II' hydrocephalus; however, we think the herpetic infection he suffered of after his birth should not be ignored.
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http://dx.doi.org/10.1159/000500719DOI Listing
June 2020

The History of Arachne Through Historic Descriptions of Meningiomas with Hyperostosis: From Prehistory to the Present.

World Neurosurg 2019 Aug 29;128:37-46. Epub 2019 Apr 29.

Department of Neurosurgery, "Grigore. T. Popa" University of Medicine and Pharmacy, Iasi, Romania.

Background: Intracranial meningiomas are brain tumors that have probably been known the longest, largely because of the occasional production of grotesque cranial deformities that have attracted the attention and interest of humankind. Because of the tendency of some intracranial meningiomas to cause skull deformation and thickening, these tumors have given rise to various speculations and theories related to their origin, starting in prehistoric times up to the present.

Methods: From the Steinheim skull and "pharaonic meningiomas" to the first meningioma monograph and the first explanations of Harvey Cushing regarding the mechanism of hyperostosis, this review aims to weave again the story of Arachne. We identify the main contributors who have tried to understand and explain the tendency of some of these tumors to cause hyperostosis or other skull bone involvements.

Conclusions: The contribution of neurosurgeons or pathologists over the centuries is of undeniable importance and is the basis for understanding future molecular mechanisms.
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http://dx.doi.org/10.1016/j.wneu.2019.04.199DOI Listing
August 2019

Fourteenth Century Iconography of Digital Clubbing in Prince William II of Aragon (1312-1338).

Chest 2019 04;155(4):880-882

Warwick Medical School, Microbiology and Infection Unit, The University of Warwick; Legal Medicine Section, Department of Public Health and Paediatric Sciences, University of Turin, Turin, Italy; UMR 7268, Laboratoire d'Anthropologie bio-culturelle, Droit, Etique & Santé (Adés), Faculté de Médecine de Marseille, Montigny-Le-Bretonneux, France. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2019.01.022DOI Listing
April 2019

Open Tension Pneumothorax in "The Dying Niobid" (Uffizi Gallery).

Chest 2019 04;155(4):878-880

Warwick Medical School, Microbiology and Infection Unit, The University of Warwick, Coventry, England; Legal Medicine Section, Department of Public Health and Paediatric Sciences, University of Turin, Turin, Italy; UMR 7268, Laboratoire d'Anthropologie bio-culturelle, Droit, Etique & Santé (Adés), Faculté de Médecine de Marseille, Montigny-Le-Bretonneux, France. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2018.12.028DOI Listing
April 2019

The Anatomy of Papal Tiara: A Story About Popes' Contribution and Protection of Anatomists.

J Relig Health 2019 Aug;58(4):1307-1327

2nd Neurosurgery Clinic, "Prof. Dr. N. Oblu Emergency Clinical Hospital", Iasi, Romania.

Beginning with the thirteenth century, the papacy has exerted an important role in the development of anatomy and medical sciences through the protection and support provided to anatomists, who were in most cases the personal physicians of the popes as well. The work is intended to be a lesson of anatomy of Papal tiara, presenting the most important contributing popes, the anatomists-physicians whom they supported and protected and the relations between papacy and medical sciences.
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http://dx.doi.org/10.1007/s10943-019-00772-3DOI Listing
August 2019

Neurological disorder? No, Mannerism.

Lancet Neurol 2019 02;18(2):135

Legal Medicine Section, Department of Public Health and Paediatric Sciences, University of Turin, Italy; Warwick Medical School, Microbiology and Infection Division, University of Warwick, Coventry, UK; UMR 7268, Laboratoire d'Anthropologie bio-culturelle, Droit, Etique & Santé (Adés), Faculté de Médecine de Marseille, Marseille, France.

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http://dx.doi.org/10.1016/S1474-4422(18)30447-2DOI Listing
February 2019

A case of sepsis in a 17th century man from Porto Ercole.

Lancet Infect Dis 2019 01;19(1):25

Legal Medicine Section, Department of Public Health and Paediatric Sciences, University of Turin, Turin, Italy; Warwick Medical School, Microbiology and Infection Unit, University of Warwick, CV4 7AL Coventry, UK; UMR 7268, Laboratoire d'Anthropologie bio-culturelle, Droit, Etique & Santé (Adés), Faculté de Médecine de Marseille, Marseille, France. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(18)30719-9DOI Listing
January 2019

Evidence of hypothyroidism in a portrait by Lorenzo Lotto.

Lancet Diabetes Endocrinol 2019 01;7(1):14

Legal Medicine Section, Department of Public Health and Paediatric Sciences, University of Turin, Turin, Italy; Warwick Medical School, Microbiology and Infection Division, University of Warwick, Warwick, UK; UMR 7268, Laboratoire d'Anthropologie Bio-Culturelle, Droit, Etique & Santé (Adés), Faculté de Médecine de Marseille, Aix-Marseille Université, Marseille, France. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(18)30342-5DOI Listing
January 2019

Amedeo Modigliani and his "great secret": a brief history of medical and social aspects of tuberculosis in the nineteenth and early twentieth century.

Infez Med 2018 Sep;26(3):280-282

New Mexico Health Enhancement and Marathon Clinics Research Foundation, Albuquerque, NM, USA; New Mexico Museum of Natural History and Science, Albuquerque NM, USA.

The pathography of the famous painter and sculptor Amedeo Modigliani (1884-1920) shows that he had tuberculosis and died of tubercular meningitis aged 35. The nineteenth century was characterized by numerous milestones in the history of tuberculosis. In 1853, Hermann Brehmer, first used the term tuberculosis referred to at the time as "phthisis". In 1865, Jean Antoine Villemin demonstrated the infectious etiology of the disease. This was confirmed in 1882 by Robert Koch by identifying the tubercle bacillus. Koch also invented the diagnostic tuberculin test. Charles Mantoux and Florence Seibert improved this test. Identification of the infectious etiology of tuberculosis led to experiments of effective treatments for this disease. The most successful treatment for tuberculosis was by sanatorium regime. From the late nineteenth century, more invasive therapeutic approaches such as artificial pneumothorax were introduced. The advent of streptomycin in 1945 changed the social view of tuberculosis. This previously romanticized disease became a social stigma which was associated with poor social and moral standards; patients were kept in isolation. Fearing social ostracism, Modigliani refused treatment for tuberculosis and instead deliberately fostered his reputation as an alcoholic and addict in order to conceal the disease.
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September 2018

Young Frankenstein and The Lancet.

Lancet 2018 09;392(10149):736

Legal Medicine Section, Department of Public Health and Paediatric Sciences, University of Turin, Turin, Italy; Microbiology and Infection Division, Warwick Medical School, University of Warwick, Warwick, UK; UMR 7268, Laboratoire d'Anthropologie bio-culturelle, Droit, Etique & Santé (Adés), Faculté de Médecine de Marseille, Marseille, France.

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http://dx.doi.org/10.1016/S0140-6736(18)31507-1DOI Listing
September 2018