Antonio Marchetti

Antonio Marchetti

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Antonio Marchetti

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Correlation of ROS1 Immunohistochemistry With Fusion Status Determined by Fluorescence In Situ Hybridization.

Arch Pathol Lab Med 2019 Sep 11. Epub 2019 Sep 11.

From Roche Molecular Solutions, Pleasanton, California (Dr Huang, Mr Smith, Dr Le, Mr Liu, Dr Ordinario, Dr Manohar, Mr Lee, Mr Rajamani, Mr Truong, Dr Jing Li, Ms Choi, Dr Jingchuan Li, Dr Pati, Ms Hanlon Newell, Mr Pate, and Dr Menzl); Institute of Pathology, University Hospital Basel, Basel, Switzerland (Dr Bubendorf); Institute for Pathology, University Hospital, Cologne, Germany (Dr Buettner); the Department of Pathology, Aberdeen University Medical School & Aberdeen Royal Infirmary, Foresterhill, Aberdeen, United Kingdom (Dr Kerr); Laboratorio de Dianas Terapeuticas, HM Hospitales, Spain (Dr Lopez-Rios); Center of Predictive Molecular Medicine, CeSIMeT, University of Chieti-Pescara, Italy (Dr Marchetti); Pfizer Oncology, International Developed Markets, Berlin, Germany (Ms Marondel); the Department of Histopathology, Royal Brompton and Harefield Hospitals, and National Heart and Lung Division, Imperial College, London, United Kingdom (Dr Nicholson); the Pathology Department, Istanbul University, Cerrahpassa Medical Faculty, Istanbul, Turkey (Dr Öz); CORE, Antwerp University, and the Department of Pathology, Antwerp University Hospital, Antwerp, Belgium (Mr Pauwels); the Department of Biopathology, Centre Jean Perrin & INSERM U240 IMoST and Université Clermont Auvergne, Clermont-Ferrand, France (Dr Penault-Llorca); Operative Unit of Pathology, AUSL della Romagna, Hospital S. Maria delle Croci, Ravenna, Italy (Dr Rossi); and the Department of Pathology, VU University Medical Center, Amsterdam, the Netherlands (Dr Thunnissen).

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http://dx.doi.org/10.5858/arpa.2019-0085-OADOI Listing
September 2019

Ventana ALK (D5F3) in the Detection of Patients Affected by Anaplastic Lymphoma Kinase-positive Non-Small-cell Lung Cancer: Clinical and Budget Effect.

Clin Lung Cancer 2018 09 31;19(5):e735-e743. Epub 2018 May 31.

Center of Predictive Molecular Medicine, Center of Excellence on Aging University-Foundation, Chieti, Italy.

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http://dx.doi.org/10.1016/j.cllc.2018.05.012DOI Listing
September 2018

Why anti-PD1/PDL1 therapy is so effective? Another piece in the puzzle.

J Thorac Dis 2017 Dec;9(12):4863-4866

Center of Predictive Molecular Medicine, CeSI-MeT, University of Chieti, Chieti, Italy.

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http://dx.doi.org/10.21037/jtd.2017.11.105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756957PMC
December 2017

Is chronic kidney disease-mineral and bone disorder associated with the presence of endothelial progenitor cells with a calcifying phenotype?

Clin Kidney J 2017 Jun 15;10(3):389-396. Epub 2017 Feb 15.

Department of Experimental Diagnostic and Specialty Medicine (DIMES), Nephrology, Dialysis and Renal Transplant Unit, St Orsola Hospital, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1093/ckj/sfw145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466108PMC
June 2017

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine: Part 4: Tissue Tools for Quality Assurance in Immunohistochemistry.

Appl Immunohistochem Mol Morphol 2017 04;25(4):227-230

*Department of Laboratory Medicine and Pathobiology, University of Toronto Departments of †Pathology §§§§Laboratory Hematology, University Health Network, Toronto, ON §§Vancouver General Hospital, University of British Columbia, Vancouver, BC ###Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB ∥∥∥∥Canadian Immunohistochemistry Quality Control (CIQC)/Canadian Association of Pathologists National Standards Committee for High Complexity Testing/Immunohistochemistry, Canada ‡Poundbury Cancer Institute §Dorset County Hospital NHS Foundation Trust ∥Cancer Diagnostic Quality Assurance Services (CADQAScic), Dorchester ¶¶Department of Surgery & Cancer, Division of Cancer, Imperial College London ***UK National External Quality Assessment Scheme (UK NEQAS), University College London, London, UK ∥∥International Quality Network for Pathology (IQN Path), Luxembourg City, Luxembourg ¶School of Medicine, Institute of Pathology, Charité-University Hospital Berlin, Berlin, Germany #Griffith University, Gold Coast ††Genomics For Life, Brisbane, Qld **RCPA Quality Assurance Program, Sydney, NSW, Australia ‡‡Phenopath, Seattle, WA ##Brigham and Women's Hospital, Harvard Medical School, Boston, MA ****Keck School of Medicine, University of Southern California, Los Angeles, CA †††Center of Predictive Molecular Medicine ‡‡‡Center for Excellence on Ageing and Translational Medicine, University of Chieti-Pescara, Chieti, Italy §§§Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands ∥∥∥Institute of Pathology, Aalborg University Hospital and Department of Clinical Medicine, Aalborg University ¶¶¶Nordic Immunohistochemistry Quality Control (NordiQC), Aalborg, Denmark ††††Department of Pathology, Beijing Friendship Hospital, Capital Medical University, Beijing ‡‡‡‡Chinese Committee for Pathologists-Immunohistochemistry Quality Control, China.

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http://dx.doi.org/10.1097/PAI.0000000000000469DOI Listing
April 2017

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine. Part 3: Technical Validation of Immunohistochemistry (IHC) Assays in Clinical IHC Laboratories.

Appl Immunohistochem Mol Morphol 2017 03;25(3):151-159

*Department of Laboratory Medicine and Pathobiology, University of Toronto Departments of †Laboratory Hematology §Pathology, University Health Network, Toronto, ON ∥∥Vancouver General Hospital, University of British Columbia, Vancouver, BC ¶¶¶Department of Pathology and Laboratory Medicine, Cumming School of Medicine University of Calgary, and Calgary Laboratory Services, Calgary, AB, Canada ‡Canadian Immunohistochemistry Quality Control (CIQC), Vancouver, BC, Canada/Canadian Association of Pathologists National Standards Committee for High Complexity Testing/Immunohistochemistry ∥Poundbury Cancer Institute ¶Dorset County Hospital NHS Foundation Trust, Dorchester, UK #Cancer Diagnostic Quality Assurance Services (CADQAScic), Dorchester ***UK National External Quality Assessment Scheme (UK NEQAS), University College London, London, UK **School of Medicine, Institute of Pathology, Charité-University Hospital, Berlin, Berlin, Germany ††Griffith University, Gold Coast ‡‡RCPA Quality Assurance Program, Sydney §§Genomics For Life, Brisbane, Australia ¶¶International Quality Network for Pathology (IQN Path), Luxembourg City, Luxembourg ##Brigham and Women's Hospital, Harvard Medical School, Boston, MA †††Center of Predictive Molecular Medicine, Center for Excellence on Ageing and Translational Medicine, University of Chieti-Pescara, Chieti, Italy ‡‡‡Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands §§§Institute of Pathology, and Department of Clinical Medicine, Aalborg University, Aalborg University Hospital ∥∥∥Nordic Immunohistochemistry Quality Control (NordiQC), Aalborg, Denmark ###Department of Pathology, Beijing Friendship Hospital, Capital Medical University, Beijing ****Chinese Committee for Pathologists-Immunohistochemistry Quality Control, China ††††Keck School of Medicine, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1097/PAI.0000000000000470DOI Listing
March 2017

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine - Part 2: Immunohistochemistry Test Performance Characteristics.

Appl Immunohistochem Mol Morphol 2017 02;25(2):79-85

*Department of Laboratory Medicine and Pathobiology, University of Toronto, Vancouver, BC, CanadaDepartment of †Laboratory Hematology§Pathology, University Health Network, Toronto, ON, Canada‡Canadian Immunohistochemistry Quality Control (CIQC)/Canadian Association of Pathologists National Standards Committee for High Complexit Testing/Immunohistochemistry∥Poundbury Cancer Institute¶Dorset County Hospital NHS Foundation Trust#Cancer Diagnostic Quality Assurance Services (CADQAScic), Dorchester, UK***UK National External Quality Assessment Scheme (UK NEQAS), University College London, London, UK**"Rudolf-Virchow-Haus", Institute of Pathology, Charité-University Hospital Berlin, Berlin, Germany††School of Medicine, Griffith University, Gold Coast‡‡Genomics For Life, Brisbane, QLD§§RCPA Quality Assurance Program, Sydney, NSW, Australia∥∥Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada¶¶International Quality Network for Pathology (IQN Path), Luxembourg City, Luxembourg, and Division of Cancer, Department of Surgery & Cancer, Imperial College London, UK##Brigham and Women's Hospital, Harvard Medical School, Boston, MA†††Center of Predictive Molecular Medicine, Center for Excellence on Ageing and Translational Medicine, University of Chieti-Pescara, Chieti, Italy‡‡‡Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands§§§Institute of Pathology, Aalborg University Hospital and Department of Clinical Medicine, Aalborg University, Denmark∥∥∥Nordic Immunohistochemistry Quality Control (NordiQC), Aalborg, Denmark¶¶¶Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary and Calgary Laboratory Services, Calgary, AB###Department of Pathology, Beijing Friendship Hospital, Capital Medical University****CCP-IHCQC, Chinese Committee for Pathologists-Immunohistochemistry Quality Control, Beijing, China††††Keck School of Medicine, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1097/PAI.0000000000000444DOI Listing
February 2017

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine: Part 1: Fit-for-Purpose Approach to Classification of Clinical Immunohistochemistry Biomarkers.

Appl Immunohistochem Mol Morphol 2017 01;25(1):4-11

*Department of Laboratory Medicine and Pathobiology, University of Toronto †Department of Pathology, University Health Network ††††Department of Laboratory Hematology, University Health Network, Toronto, ON ‡‡Vancouver General Hospital, University of British Columbia, Vancouver, BC ∥∥∥Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada ‡Poundbury Cancer Institute §Dorset County Hospital NHS Foundation Trust ∥Cancer Diagnostic Quality Assurance Services (CADQAScic), Dorchester ∥∥Division of Cancer, Department of Surgery & Cancer, Imperial College, London, UK ##UK National External Quality Assessment Scheme (UK NEQAS), University College London, London, UK ¶School of Medicine, Institute of Pathology, Charité-University Hospital Berlin, Berlin, Germany #Griffith University, Gold Coast **RCPA Quality Assurance Program, Sydney ††Genomics For Life, Brisbane, Australia §§International Quality Network for Pathology (IQN Path), Luxembourg City, Luxembourg ¶¶Brigham and Women's Hospital, Harvard Medical School, Boston, MA ***Center of Predictive Molecular Medicine, Center for Excellence on Ageing and Translational Medicine, University of Chieti-Pescara, Chieti, Italy †††Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands ‡‡‡Institute of Pathology, Aalborg University Hospital and Department of Clinical Medicine, Aalborg University §§§Nordic Immunohistochemistry Quality Control (NordiQC), Aalborg, Denmark ¶¶¶Keck School of Medicine, University of Southern California, Los Angeles, CA ###Department of Pathology, Beijing Friendship Hospital, Capital Medical University, Beijing, China ****Chinese Committee for Pathologists-Immunohistochemistry Quality Control ‡‡‡‡Canadian Immunohistochemistry Quality Control (CIQC)/Canadian Association of Pathologists National Standards Committee for High Complexity Testing/Immunohistochemistry, Vancouver, BC, Canada.

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http://dx.doi.org/10.1097/PAI.0000000000000451DOI Listing
January 2017

Comparison of Two Parathyroid Hormone Assays in Hemodialysis Patients.

Artif Organs 2016 Oct 16;40(10):1013-1016. Epub 2015 Dec 16.

Nephrology Dialysis and Renal Transplantation Unit, S. Orsola University Hospital, Bologna, Italy.

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http://doi.wiley.com/10.1111/aor.12661
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http://dx.doi.org/10.1111/aor.12661DOI Listing
October 2016

ALK Protein Analysis by IHC Staining after Recent Regulatory Changes: A Comparison of Two Widely Used Approaches, Revision of the Literature, and a New Testing Algorithm.

J Thorac Oncol 2016 Apr 22;11(4):487-95. Epub 2016 Feb 22.

Oncological and Cardiovascular Molecular Medicine Unit, Center for Excellence on Ageing and Translational Medicine, University of Chieti-Pescara, Chieti, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2015.12.111DOI Listing
April 2016

Assessment of EGFR mutations in circulating tumor cell preparations from NSCLC patients by next generation sequencing: toward a real-time liquid biopsy for treatment.

PLoS One 2014 19;9(8):e103883. Epub 2014 Aug 19.

Center of Predictive Molecular Medicine, Center of Excellence on Aging, University-Foundation, Chieti, Italy; Oncological and Cardiovascular Molecular Medicine Unit, Center of Excellence on Aging, University-Foundation, Chieti, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0103883PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138040PMC
October 2015

Early Prediction of Response to Tyrosine Kinase Inhibitors by Quantification of EGFR Mutations in Plasma of NSCLC Patients.

J Thorac Oncol 2015 Oct;10(10):1437-43

*Center of Predictive Molecular Medicine, Ce.S.I., G. D'Annunzio University-Foundation, Chieti, Italy; †Medical Scientific Affairs Department, Roche Molecular Systems, Pleasanton, California; ‡Oncological and Cardiovascular Molecular Medicine Unit, Ce.S.I., G. D'Annunzio University-Foundation, Chieti, Italy; §Division of Thoracic Oncology, European Institute of Oncology, Milan, Italy; ‖Department of Medical Oncology, S. Maria della Misericordia Hospital, Perugia, Italy; ¶Department of Medical Oncology, Bellaria-Maggiore Hospital, Azienda USL of Bologna, Bologna, Italy; #Unit of Pneumology, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy; **Ospedale Civile di Pescara, Pescara, Italy; ††Ospedale Civile di Sulmona, Sulmona, Italy; ‡‡Department of Medical Oncology, Consorzio Interuniversitario Nazionale per la Bio-Oncologia, G. d'Annunzio University, Chieti, Italy; §§Department of Oncology-Haematology, Humanitas Cancer Center, IRCCS, Milan, Italy; and ‖‖Perugia University Medical School, Perugia, Italy.

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http://dx.doi.org/10.1097/JTO.0000000000000643DOI Listing
October 2015

Phase II study of afatinib, an irreversible ErbB family blocker, in EGFR FISH-positive non-small-cell lung cancer.

J Thorac Oncol 2015 Apr;10(4):665-72

*Istituto Toscano Tumori, Ospedale Civile di Livorno, Livorno, Italy; †Humanitas Cancer Center, Istituto Clinico Humanitas IRCCS, Rozzano, Italy; ‡IRCCS AOU San Martino IST - Istituto Nazionale per la Ricerca sul Cancro, Lung Cancer Unit, Genova, Italy; §San Gerardo Hospital, Monza, Italy; ‖Istituto Oncologico Veneto IRCSS, Padova, Italy; ¶Clinical Research Center, Center of Excellence on Aging, University Foundation, Chieti, Italy; #IRCCS Humanitas Clinical Institute, Rozzano, Milan, Italy; **Boehringer Ingelheim Pharma GmbH & Co. KG, Vienna, Austria; ††Boehringer Ingelheim Italia SpA, Milan, Italy; and ‡‡Boehringer Ingelheim Ltd., Bracknell, UK.

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http://dx.doi.org/10.1097/JTO.0000000000000442DOI Listing
April 2015

Lungscape: resected non-small-cell lung cancer outcome by clinical and pathological parameters.

J Thorac Oncol 2014 Nov;9(11):1675-84

*Centre Hospitalier Universitaire de Vaud, Lausanne, Switzerland; †Division of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland; ‡Frontier Science Foundation-Hellas & University of Athens, Athens, Greece; §Aberdeen Royal Infirmary, Aberdeen, United Kingdom; ‖Institute for Pathology, University Hospital Basel, Basel, Switzerland; ¶Department of Oncology, University Hospital, Aarhus, Denmark; #Department of Medical Oncology, St. James's Hospital, Dublin, Ireland; **Medical University of Gdansk, Gdansk, Poland; ††University Hospital KU Leuven, Leuven, Belgium; ‡‡Vall d'Hebron University Hospital, Barcelona, Spain; §§Center of Predictive Molecular Medicine, University Foundation, Chieti, Italy; ‖‖Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China; ¶¶VU University Medical Center, Amsterdam, Netherlands; ##Maastricht University Medical Centre, Maastricht, Netherlands; ***Manchester University and The Christie National Health Services Foundation Trust, Manchester, United Kingdom; †††Netherlands Cancer Institute, Amsterdam, Netherlands; ‡‡‡Department of Medicine, University of Valencia and Department of Medical Oncology, General University Hospital of Valencia, Valencia, Spain; §§§Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain; and ‖‖‖Clinic of Oncology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1097/JTO.0000000000000320DOI Listing
November 2014

Determinants of noninvasive ventilation outcomes during an episode of acute hypercapnic respiratory failure in chronic obstructive pulmonary disease: the effects of comorbidities and causes of respiratory failure.

Biomed Res Int 2014 19;2014:976783. Epub 2014 Jan 19.

Alma Mater Studiorum, Department of Specialistic, Diagnostic and Experimental Medicine (DIMES), University of Bologna, 40138 Bologna, Italy ; Respiratory and Critical Care, Sant'Orsola Malpighi Hospital, Alma Mater Studiorum, Department of Specialistic, Diagnostic and Experimental Medicine (DIMES), University of Bologna, 40138 Bologna, Italy.

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http://dx.doi.org/10.1155/2014/976783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915711PMC
October 2014

ALK rearrangement testing by FISH analysis in non-small-cell lung cancer patients: results of the first italian external quality assurance scheme.

J Thorac Oncol 2014 Oct;9(10):1470-6

*Center of Predictive Molecular Medicine, Center of Excellence on Aging, University-Foundation, Chieti, Italy; †Division of Pathology and Laboratory Medicine, European Institute of Oncology, Milan, Italy; ‡Division of Anatomic Pathology, San Luigi Hospital and University of Turin, Orbassano, Italy; §Pathology Department, Policlinico di Modena, Modena, Italy; ‖Diagnostic and Laboratory Medicine, INT-Fondazione "G.Pascale", Naples, Italy; ¶Medical Oncology Unit, University Hospital, Parma, Italy; #Department of Medical Oncology, Perugia Hospital, Perugia, Italy; **Division of Medical Oncology, S.G. Moscati Hospital, Avellino, Italy; ††Department of Human Pathology and Oncology, University of Florence, Florence, Italy; ‡‡Pathology Department, Casa di Cura San Pio X and I.R.C.C.S. Policlinico San Donato, Milano, Italy; §§Thoracic Oncology Unit, University of Torino, San Luigi Hospital, Torino, Italy; ‖‖Cell Biology and Biotherapy Unit, INT-Fondazione "G.Pascale", Naples, Italy; and ¶¶Medical Oncology Unit, S. Orsola-Malpighi Hospital, Bologna, Italy.

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http://dx.doi.org/10.1097/JTO.0000000000000280DOI Listing
October 2014

Prevalence and clinical outcomes for patients with ALK-positive resected stage I to III adenocarcinoma: results from the European Thoracic Oncology Platform Lungscape Project.

J Clin Oncol 2014 Sep 28;32(25):2780-7. Epub 2014 Jul 28.

Fiona H. Blackhall and Daisuke Nonaka, Manchester University and The Christie National Health Services Foundation Trust, Manchester; Keith M. Kerr, Aberdeen University Medical School, Aberdeen Royal Infirmary, Aberdeen, United Kingdom; Solange Peters and Igor Letovanec, Centre Hospitalier Universitaire Vaudois, Lausanne; Lukas Bubendorf and Spasenija Savic, Institute for Pathology, University Hospital Basel, Basel; Alex Soltermann and Rolf A. Stahel, University Hospital Zurich, Zurich, Switzerland; Urania Dafni, Frontier Science Foundation-Hellas and University of Athens, Athens, Greece; Henrik Hager, University Hospital, Aarhus, Denmark; Kenneth J. O'Byrne, St James's Hospital, Dublin, Ireland; Christoph Dooms, University Hospital KU Leuven, Leuven, Belgium; Aleksandra Sejda, Medical University of Gdansk, Gdansk, Poland; Javier Hernández-Losa, Vall d'Hebron University Hospital, Barcelona; Miguel Martorell, Universitat de Valencia and Hospital General Universitario de Valencia, Valencia; Rafael Rosell, Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain; Antonio Marchetti, Center of Predictive Molecular Medicine, University Foundation, Chieti, Italy; Qiang Tan, Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China; Erik Thunnissen, VU University Medical Clinic Center; Jeroen de Jong, Netherlands Cancer Institute, Amsterdam; Ernst-Jan M. Speel, Maastricht University Medical Centre, Maastricht, the Netherlands; and Richard Cheney, Roswell Park Cancer Institute, Buffalo, NY.

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http://dx.doi.org/10.1200/JCO.2013.54.5921DOI Listing
September 2014

Relationship between coronary artery disease and C-reactive protein levels in NSTEMI patients with renal dysfunction: a retrospective study.

BMC Nephrol 2014 Sep 17;15:152. Epub 2014 Sep 17.

Department of Experimental, Diagnostic and Specialty Medicine, Nephrology Dialysis and Transplantation Unit, S, Orsola Hospital, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1186/1471-2369-15-152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175282PMC
September 2014

Incidence and predictors of postoperative atrial fibrillation in kidney transplant recipients.

Transplantation 2013 Dec;96(11):981-6

1 Nephrology Dialysis and Renal Transplant Unit, St. Orsola University Hospital, Bologna, Italy. 2 Cardiology Unit, University of Bologna, St. Orsola University Hospital, Bologna, Italy. 3 Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy. 4 Address correspondence to: Gaetano La Manna, M.D., Nephrology Dialysis and Renal Transplantation Unit, St. Orsola University Hospital, Massarenti 9, Bologna, Italy.

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http://dx.doi.org/10.1097/TP.0b013e3182a2b492DOI Listing
December 2013

Strategies for improving outcomes in NSCLC: a look to the future.

Lung Cancer 2013 Dec 8;82(3):375-82. Epub 2013 Sep 8.

Department of Oncology, University Hospital Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2013.08.025DOI Listing
December 2013

Ligand-dependent activation of EGFR in follicular dendritic cells sarcoma is sustained by local production of cognate ligands.

Clin Cancer Res 2013 Sep 25;19(18):5027-38. Epub 2013 Jul 25.

Authors' Affiliations: Department of Molecular and Translational Medicine, Section of Anatomic Pathology, Oncology and Experimental immunology, University of Brescia, Brescia; Department of Physiopathology, Experimental Medicine and Public Health, University of Siena, Siena; Department of Pathology, San Raffaele Scientific Institute, Milan; Center of Predictive Molecular Medicine, Center of Excellence on Aging University-Foundation, Chieti; Unita' Operativa di Anatomia Patologica, Azienda Arcispedale S. Maria Nuova/IRCCS, Reggio Emilia; Hematopathology Section, Policlinico S. Orsola, University of Bologna, Bologna; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri; and Humanitas Clinical and Research Center.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1275DOI Listing
September 2013

microRNAs derived from circulating exosomes as noninvasive biomarkers for screening and diagnosing lung cancer.

J Thorac Oncol 2013 Sep;8(9):1156-62

Center of Predictive Molecular Medicine, Center of Excellence on Aging, †Oncological and Cardiovascular Molecular Medicine Unit, University-Foundation, Chieti, Italy.

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http://dx.doi.org/10.1097/JTO.0b013e318299ac32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123222PMC
September 2013

Results of the First Italian External Quality Assurance Scheme for somatic EGFR mutation testing in non-small-cell lung cancer.

J Thorac Oncol 2013 Jun;8(6):773-8

Research Department, Cell Biology and Biotherapy Unit, INT Fondazione G.Pascale, Via M. Semmola, Naples, Italy.

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http://dx.doi.org/10.1097/JTO.0b013e31828c2b08DOI Listing
June 2013

A unique microRNA signature associated with plaque instability in humans.

Stroke 2011 Sep 4;42(9):2556-63. Epub 2011 Aug 4.

Centro di Eccellenza Europeo e di Riferimento Regionale per l'Aterosclerosi, l'Ipertensione Arteriosa e le Dislipidemie, Nuovo Policlinico SS, Annunziata, Via dei Vestini 66, 66013 Chieti, Italy.

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http://dx.doi.org/10.1161/STROKEAHA.110.597575DOI Listing
September 2011

Clinical features and outcome of patients with non-small-cell lung cancer harboring BRAF mutations.

J Clin Oncol 2011 Sep 8;29(26):3574-9. Epub 2011 Aug 8.

Center of Predictive Molecular Medicine, Center of Excellence on Aging (CeSI) University-Foundation, via Colle dell'Ara, 66100 Chieti, Italy.

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http://dx.doi.org/10.1200/JCO.2011.35.9638DOI Listing
September 2011

Mutational profile of GNAQQ209 in human tumors.

PLoS One 2009 Aug 31;4(8):e6833. Epub 2009 Aug 31.

Laboratory of Molecular Genetics, Institute for Cancer Research and Treatment, University of Torino Medical School, University of Torino, Medical School Candiolo, Torino, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0006833PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730032PMC
August 2009

Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients.

J Clin Oncol 2009 Apr 2;27(10):1667-74. Epub 2009 Mar 2.

Istituto Clinico Humanitas, Istituto di Ricovero e Cura a Carattere Scientifico, Department of Oncology-Hematology, University of Milan School of Medicine, IRCCS Istituto Clinico Humanitas, Rozzano, Italy.

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http://dx.doi.org/10.1200/JCO.2008.19.1635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341799PMC
April 2009

Identification of potential therapeutic targets in malignant mesothelioma using cell-cycle gene expression analysis.

Am J Pathol 2009 Mar 13;174(3):762-70. Epub 2009 Feb 13.

Division of Pathology, Department of Medicine, Surgery, and Dentistry, University of Milan Medical School, A.O.S. Paolo, Via A. Di Rudinì 8, 20142 Milano, Italy.

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http://dx.doi.org/10.2353/ajpath.2009.080721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665738PMC
March 2009

K-ras mutations and cetuximab in colorectal cancer.

N Engl J Med 2009 Feb;360(8):833-4; author reply 835-6

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http://dx.doi.org/10.1056/NEJMc082346DOI Listing
February 2009

Jaagsiekte sheep retrovirus is not detected in human lung adenocarcinomas expressing antigens related to the Gag polyprotein of betaretroviruses.

Cancer Lett 2007 Dec 24;258(1):22-30. Epub 2007 Sep 24.

Departmento de Patología Animal, Facultad de Veterinaria, Universidad de Zaragoza, C/Miguel Servet 177, 50013, Zaragoza, Spain.

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http://dx.doi.org/10.1016/j.canlet.2007.08.006DOI Listing
December 2007

Different prognostic roles of mutations in the helical and kinase domains of the PIK3CA gene in breast carcinomas.

Clin Cancer Res 2007 Oct;13(20):6064-9

Unit of Surgical Pathology, Laboratory of Molecular Pathology S. Chiara Hospital, Trento, Italy, and Clinical Research Center, Center of Excellence on Aging, University-Foundation, Chieti, Italy.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-0266DOI Listing
October 2007

Loss of beta4 integrin subunit reduces the tumorigenicity of MCF7 mammary cells and causes apoptosis upon hormone deprivation.

Clin Cancer Res 2006 Jun;12(11 Pt 1):3280-7

Molecular Oncogenesis Laboratory, Department of Experimental Oncology, Regina Elena Cancer Institute, Rome, Italy.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-05-2223DOI Listing
June 2006

Assessing EGFR mutations.

N Engl J Med 2006 Feb;354(5):526-8; author reply 526-8

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http://dx.doi.org/10.1056/NEJMc052564DOI Listing
February 2006

Quantitative evaluation of the apoptosis regulating genes Survivin, Bcl-2 and Bax in inflammatory and malignant pleural lesions.

Lung Cancer 2005 May 10;48(2):211-6. Epub 2004 Dec 10.

Department of Medicine Surgery and Dentistry, Division of Pathology, University of Milan, AO San Paolo e IRCCS Ospedale Maggiore, Via A. Di Rudinì 8, 20142 Milan, Italy.

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http://dx.doi.org/10.1016/j.lungcan.2004.10.003DOI Listing
May 2005

HER-2/Neu alterations in non-small cell lung cancer: a comprehensive evaluation by real time reverse transcription-PCR, fluorescence in situ hybridization, and immunohistochemistry.

Clin Cancer Res 2003 Sep;9(10 Pt 1):3645-52

Division of Pathology, Department of Medicine, Surgery and Dental Sciences, University of Milan, A.O. S. Paolo and IRCCS Ospedale Maggiore, 20142 Milan, Italy

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September 2003

Images in cardiovascular medicine. Membrane-type subaortic stenosis in the adult.

Ital Heart J 2003 Sep;4(9):651-2

Department of Cardiology and Cardiac Surgery, G. d'Annunzio University, Chieti, Italy.

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September 2003

Survivin gene expression in early-stage non-small cell lung cancer.

J Pathol 2003 Aug;200(5):620-6

Department of Medicine, Surgery and Dental Sciences, Division of Pathology, University of Milan, AO S Paolo, Via A Di Rudini 8, 20142 Milan, Italy.

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http://dx.doi.org/10.1002/path.1388DOI Listing
August 2003