Publications by authors named "Antonio M Risitano"

94Publications

Author Correction: Complement as a target in COVID-19?

Nat Rev Immunol 2020 07;20(7):448

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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July 2020

The first case of COVID-19 treated with the complement C3 inhibitor AMY-101.

Clin Immunol 2020 06 29;215:108450. Epub 2020 Apr 29.

Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; University Vita Salute San Raffaele, Milan, Italy. Electronic address:

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June 2020

Complement as a target in COVID-19?

Nat Rev Immunol 2020 06 23;20(6):343-344. Epub 2020 Apr 23.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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June 2020

T-PLL: harmonizing criteria for research.

Blood 2019 10;134(14):1113-1114

Federico II University of Naples.

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October 2019

The Case for Upfront HLA-Matched Unrelated Donor Hematopoietic Stem Cell Transplantation as a Curative Option for Adult Acquired Severe Aplastic Anemia.

Biol Blood Marrow Transplant 2019 09 24;25(9):e277-e284. Epub 2019 May 24.

Department of Haematological Medicine, King's College Hospital/King's College London, London, UK.

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September 2019

Eltrombopag for post-transplant cytopenias due to poor graft function.

Bone Marrow Transplant 2019 08 24;54(8):1346-1353. Epub 2019 Jan 24.

Hematology, Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy.

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August 2019

Expanding Complement Therapeutics for the Treatment of Paroxysmal Nocturnal Hemoglobinuria.

Semin Hematol 2018 07 14;55(3):167-175. Epub 2018 Feb 14.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Electronic address:

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July 2018

Therapeutic complement modulation for hematological diseases: Where we stand and where we are going.

Semin Hematol 2018 07 29;55(3):113-117. Epub 2018 May 29.

Hematology, Department of Clinical Medicine and Surgery; Federico II University, Naples, Italy. Electronic address:

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July 2018

Advances in understanding the pathogenesis of acquired aplastic anaemia.

Br J Haematol 2018 09 5;182(6):758-776. Epub 2018 Jul 5.

Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy.

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September 2018

(Auto-)immune signature in aplastic anemia.

Haematologica 2018 05;103(5):747-749

Hematology, Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy

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May 2018

Toward complement inhibition 2.0: Next generation anticomplement agents for paroxysmal nocturnal hemoglobinuria.

Am J Hematol 2018 08 25;93(4):564-577. Epub 2018 Jan 25.

Hematology, Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy.

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August 2018

Acute immune toxicity during anti-thymocyte globulin: That's CARPA!

Am J Hematol 2018 01 3;93(1):E22-E24. Epub 2017 Nov 3.

Department of clinical medicine and surgery, Federico II University, Naples NA, Italy.

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January 2018

Eculizumab treatment: stochastic occurrence of C3 binding to individual PNH erythrocytes.

J Hematol Oncol 2017 06 19;10(1):126. Epub 2017 Jun 19.

Laboratory of Cancer Genetics and Gene Transfer, Core Research Laboratory - Istituto Toscano Tumori (CRL-ITT), AOU Careggi, viale Pieraccini 6, 50139, Florence, Italy.

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June 2017

Immune insights into AA.

Blood 2017 05;129(21):2824-2826

FEDERICO II UNIVERSITY OF NAPLES.

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May 2017

Compstatin Cp40 blocks hematin-mediated deposition of C3b fragments on erythrocytes: Implications for treatment of malarial anemia.

Clin Immunol 2016 Oct 18;171:32-35. Epub 2016 Aug 18.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, United States. Electronic address:

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October 2016

Therapeutic complement inhibition in complement-mediated hemolytic anemias: Past, present and future.

Semin Immunol 2016 06 23;28(3):223-40. Epub 2016 Jun 23.

Hematology, Department of Clinical Medicine and Surgery; Federico II University, Naples, Italy.

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June 2016

Paroxysmal nocturnal hemoglobinuria in the era of complement inhibition.

Am J Hematol 2016 Jun;91(4):359-60

BMT Unit, Federico II University, Naples, Italy.

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June 2016

Eculizumab in Pregnant Patients with Paroxysmal Nocturnal Hemoglobinuria.

N Engl J Med 2015 Sep;373(11):1032-9

From Department of Haematology, St. James's University Hospital, Leeds (R.J.K., A.H.), and Haematological Medicine, Kings College Hospital, London (A.K.) - both in the United Kingdom; University of Ulm and German Red Cross Blood Transfusion Service Baden-Württemberg-Hessen, Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, Ulm (B.H., H.S.), and Department of Hematology, University Hospital of Essen, Essen (A.R.) - both in Germany; PNH Subcommittee of the Severe Aplastic Anemia Working Party of the European Group for Blood and Marrow Transplantation, Leiden (B.H., A.K., A.M.R., L.T., H.S., R.P.L.), and Radboud University Medical Center, Nijmegen (P.M.) - both in the Netherlands; Department of Clinical Haematology, the Royal Melbourne Hospital and University of Melbourne, Parkville, VIC, Australia (J.S.); Department of Hematology, University Hospital, Rennes (S.G.), Clinical Immunology, Department of Internal Medicine, University Hospital of Lille, Lille (L.T.), and Assistance Publique-Hôpitaux de Paris, Service d'Hématologie-Greffe, Hôpital Saint-Louis, University Paris Diderot, Sorbonne Paris Cité, Centre de Référence Aplasie Médullaire-HPN, and Filière de Santé Maladie Rare Immuno-Hématologique (MARIH), Paris (R.P.L.) - all in France; Jane Anne Nohl Division of Hematology, Keck School of Medicine of University of Southern California, Los Angeles (I.C.W.); Department of Hematology, Helsinki University Central Hospital, Helsinki (E.A.); Hematology, Department of Clinical Medicine and Surgery, Federico II, University of Naples, Naples, Italy (A.M.R.); Hematology and Thromboembolism, McMaster University, Hamilton, ON, Canada (C.J.P.); and ICON Clinical Research, San Francisco (M.P.T.).

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September 2015

Applying complement therapeutics to rare diseases.

Clin Immunol 2015 Dec 1;161(2):225-40. Epub 2015 Sep 1.

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

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December 2015

Complement C3dg-mediated erythrophagocytosis: implications for paroxysmal nocturnal hemoglobinuria.

Blood 2015 Aug 16;126(7):891-4. Epub 2015 Jun 16.

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA;

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August 2015

Current and future pharmacologic complement inhibitors.

Hematol Oncol Clin North Am 2015 Jun 4;29(3):561-82. Epub 2015 Apr 4.

Bone Marrow Transplantation Clinical Unit, Hematology, Department of Clinical Medicine and Surgery, Federico II University of Naples, Via Pansini 5, Naples 80131, Italy. Electronic address:

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June 2015

Compstatin: a C3-targeted complement inhibitor reaching its prime for bedside intervention.

Eur J Clin Invest 2015 Apr 9;45(4):423-40. Epub 2015 Mar 9.

Division of Biodiagnostic Sciences and Technologies, INRASTES, National Center for Scientific Research 'Demokritos', Aghia Paraskevi Attikis, Greece.

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April 2015

Dissecting complement blockade for clinic use.

Blood 2015 Jan;125(5):742-4

FEDERICO II UNIVERSITY.

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January 2015

Anti-Complement Treatment in Paroxysmal Nocturnal Hemoglobinuria: Where we Stand and Where we are Going.

Transl Med UniSa 2014 Jan 4;8:43-52. Epub 2014 Feb 4.

Hematology, Department of Clinical Medicine and Surgery; Federico II University , Naples (Italy).

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January 2014

Clonal non-malignant hematological disorders: unraveling molecular pathogenic mechanisms to develop novel targeted therapeutics.

Transl Med UniSa 2014 Jan 4;8:1-3. Epub 2014 Feb 4.

Hematology and Hematopoietic Stem Cell Transplant Center, Department of Medicine and Surgery, University of Salerno , Italy.

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January 2014

Rational engineering of a minimized immune inhibitor with unique triple-targeting properties.

J Immunol 2013 Jun 24;190(11):5712-21. Epub 2013 Apr 24.

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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June 2013

Paroxysmal nocturnal hemoglobinuria and the complement system: recent insights and novel anticomplement strategies.

Adv Exp Med Biol 2013 ;735:155-72

Division of Hematology, Department of Biochemistry and Medical Biotechnologies, Federico II University of Naples, Via Pansini 5, 80131 Naples Italy.

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March 2013

Paroxysmal nocturnal hemoglobinuria and other complement-mediated hematological disorders.

Immunobiology 2012 Nov;217(11):1080-7

Department of Biochemistry and Medical Biotechnologies, Federico II University, Naples, Italy.

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November 2012

Immunosuppressive therapies in the management of acquired immune-mediated marrow failures.

Curr Opin Hematol 2012 Jan;19(1):3-13

Department of Biochemistry and Medical Biotechnologies, Federico II University of Naples, Naples, Italy.

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January 2012

Aplastic anemia: immunosuppressive therapy in 2010.

Pediatr Rep 2011 Jun;3 Suppl 2:e7

Department of Biochemistry and Medical Biotechnologies, Federico II University of Naples, Naples, Italy.

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June 2011

Immunosuppressive therapies in the management of immune-mediated marrow failures in adults: where we stand and where we are going.

Br J Haematol 2011 Jan 1;152(2):127-40. Epub 2010 Dec 1.

Department of Biochemistry and Medical Biotechnologies, Federico II University of Naples, Italy.

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January 2011

Paroxysmal nocturnal hemoglobinuria: pathophysiology, natural history and treatment options in the era of biological agents.

Biologics 2008 Jun;2(2):205-22

Hematology, Department of Biochemistry and Medical Biotechnologies, Federico II, University of Naples, Italy.

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June 2008

Function and malfunction of hematopoietic stem cells in primary bone marrow failure syndromes.

Curr Stem Cell Res Ther 2007 Jan;2(1):39-52

Division of Hematology, Federico II University of Naples, Via Pansini 5, 80131 Naples, Italy.

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January 2007

Aplastic anemia: management of adult patients.

Hematology Am Soc Hematol Educ Program 2005 :110-7

The Cleveland Clinic Foundation, Taussig Cancer Center, Cleveland Clinic College of Medicine of the Case Western Reserve University, Cleveland, Ohio 44195, USA.

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November 2009

New challenges to developing animal models for human immune-mediated marrow failure.

Clin Med Res 2005 May;3(2):63-4

Division of Hematology, Federico II University of Naples, Via Pansini 5, 80131 Naples, Italy.

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May 2005

Transcript profile of CD4+ and CD8+ T cells from the bone marrow of acquired aplastic anemia patients.

Exp Hematol 2004 Sep;32(9):806-14

Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

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September 2004

Clinical implications of T cell receptor repertoire analysis after allogeneic stem cell transplantation.

Hematology 2004 Jun;9(3):189-98

Experimental Hematology and Hematopoiesis Section, Cleveland Clinic Foundation, Cleveland, OH, USA.

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June 2004

Elevated circulating endothelial membrane microparticles in paroxysmal nocturnal haemoglobinuria.

Br J Haematol 2004 Jun;125(6):804-13

Laboratory of Cellular Hematology, Division of Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD, USA.

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June 2004

Molecular analysis of TCR clonotypes in LGL: a clonal model for polyclonal responses.

J Immunol 2004 Feb;172(3):1960-9

Experimental Hematology and Hematopoiesis Section, and Hematopathology Section, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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February 2004

Selective reduction of natural killer T cells in the bone marrow of aplastic anaemia.

Br J Haematol 2002 Dec;119(3):803-9

Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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December 2002

Acute lymphoblastic leukemia in the context of a disorder resembling X-linked lymphoproliferative (XLP) syndrome.

Haematologica 2002 Aug;87(8):ELT36

Divisione di Ematologia, Facoltà di Medicina, Università Federico II, Viale Augusto 148, 80125 Naples, Italy.

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August 2002

Activated platelets of patients with paroxysmal nocturnal hemoglobinuria express cellular prion protein.

Blood 2002 Jul;100(1):341-3

Laboratory of Cellular Hematology, Division of Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA.

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July 2002

A pilot study of the recombinant soluble human tumour necrosis factor receptor (p75)-Fc fusion protein in patients with myelodysplastic syndrome.

Br J Haematol 2002 Apr;117(1):119-26

Hematology Branch and Office of Biostatistics Research, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

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April 2002