Antonio Gómez-Muñoz

Antonio Gómez-Muñoz

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Antonio Gómez-Muñoz

Antonio Gómez-Muñoz

Publications by authors named "Antonio Gómez-Muñoz"

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The Role of Ceramide 1-Phosphate in Tumor Cell Survival and Dissemination.

Adv Cancer Res 2018 24;140:217-234. Epub 2018 May 24.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Bilbao, Spain.

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http://dx.doi.org/10.1016/bs.acr.2018.04.012DOI Listing
September 2019

Vitamin E alleviates non-alcoholic fatty liver disease in phosphatidylethanolamine N-methyltransferase deficient mice.

Biochim Biophys Acta Mol Basis Dis 2019 01 6;1865(1):14-25. Epub 2018 Oct 6.

Group on the Molecular and Cell Biology of Lipids, University of Alberta, Edmonton, AB, Canada; Department of Biochemistry, University of Alberta, Edmonton, AB, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09254439183038
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http://dx.doi.org/10.1016/j.bbadis.2018.10.010DOI Listing
January 2019

Regulation of adipogenesis by ceramide 1-phosphate.

Exp Cell Res 2018 11 27;372(2):150-157. Epub 2018 Sep 27.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48080 Bilbao, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2018.09.021DOI Listing
November 2018

Implication of Ceramide Kinase in Adipogenesis.

Mediators Inflamm 2017 20;2017:9374563. Epub 2017 Jul 20.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48080 Bilbao, Spain.

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http://dx.doi.org/10.1155/2017/9374563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603748PMC
June 2018

Lysophosphatidic Acid Signaling Axis Mediates Ceramide 1-Phosphate-Induced Proliferation of C2C12 Myoblasts.

Int J Mol Sci 2018 Jan 4;19(1). Epub 2018 Jan 4.

Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Viale GB Morgagni 50, 50134 Firenze, Italy.

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http://www.mdpi.com/1422-0067/19/1/139
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http://dx.doi.org/10.3390/ijms19010139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796088PMC
January 2018

Vascular endothelial growth factor mediates ceramide 1-phosphate-stimulated macrophage proliferation.

Exp Cell Res 2017 12 31;361(2):277-283. Epub 2017 Oct 31.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48080 Bilbao, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2017.10.027DOI Listing
December 2017

Potential of ceramide 1-phosphate as a novel therapeutic agent in pulmonary inflammation.

Expert Rev Clin Pharmacol 2016 24;9(5):629-31. Epub 2016 Feb 24.

b Department of Biochemistry and Molecular Biology, Faculty of Science and Technology , University of the Basque Country (UPV/EHU) , Bilbao , Spain.

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http://dx.doi.org/10.1586/17512433.2016.1152181DOI Listing
December 2016

Excess Folic Acid Increases Lipid Storage, Weight Gain, and Adipose Tissue Inflammation in High Fat Diet-Fed Rats.

Nutrients 2016 Sep 23;8(10). Epub 2016 Sep 23.

Department of Agricultural, Food & Nutritional Science, University of Alberta, Edmonton, AB T6G2P5, Canada.

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http://dx.doi.org/10.3390/nu8100594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083982PMC
September 2016

Implication of matrix metalloproteinases 2 and 9 in ceramide 1-phosphate-stimulated macrophage migration.

Cell Signal 2016 08 6;28(8):1066-74. Epub 2016 May 6.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48080 Bilbao, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2016.05.005DOI Listing
August 2016

Regulation of cell migration and inflammation by ceramide 1-phosphate.

Biochim Biophys Acta 2016 May 11;1861(5):402-9. Epub 2016 Feb 11.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), P.O. Box 644, 48080 Bilbao, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2016.02.007DOI Listing
May 2016

Ceramide 1-phosphate regulates cell migration and invasion of human pancreatic cancer cells.

Biochem Pharmacol 2016 Feb 18;102:107-119. Epub 2015 Dec 18.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48080 Bilbao, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2015.12.009DOI Listing
February 2016

Caged ceramide 1-phosphate (C1P) analogs: Novel tools for studying C1P biology.

Chem Phys Lipids 2016 Jan 29;194:79-84. Epub 2015 Jul 29.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), P.O. Box 644, 48080 Bilbao, Spain.

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http://dx.doi.org/10.1016/j.chemphyslip.2015.07.019DOI Listing
January 2016

Control of inflammatory responses by ceramide, sphingosine 1-phosphate and ceramide 1-phosphate.

Prog Lipid Res 2016 Jan 15;61:51-62. Epub 2015 Dec 15.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), P.O. Box 644, 48080 Bilbao, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.plipres.2015.09.002DOI Listing
January 2016

Regulation of ceramide generation during macrophage apoptosis by ASMase and de novo synthesis.

Biochim Biophys Acta 2015 Nov 4;1851(11):1482-9. Epub 2015 Aug 4.

Department of Medicine, University of British Columbia, Vancouver, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2015.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026326PMC
November 2015

Vagus nerve contributes to the development of steatohepatitis and obesity in phosphatidylethanolamine N-methyltransferase deficient mice.

J Hepatol 2015 Apr 27;62(4):913-20. Epub 2014 Nov 27.

Group on the Molecular and Cell Biology of Lipids, and Department of Agricultural, Food & Nutritional Science, University of Alberta, Edmonton, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01688278140087
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http://dx.doi.org/10.1016/j.jhep.2014.11.026DOI Listing
April 2015

Sphingomyelinase D/ceramide 1-phosphate in cell survival and inflammation.

Toxins (Basel) 2015 Apr 29;7(5):1457-66. Epub 2015 Apr 29.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48080 Bilbao, Spain.

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http://dx.doi.org/10.3390/toxins7051457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448157PMC
April 2015

Decreased lipogenesis in white adipose tissue contributes to the resistance to high fat diet-induced obesity in phosphatidylethanolamine N-methyltransferase-deficient mice.

Biochim Biophys Acta 2015 Feb 15;1851(2):152-62. Epub 2014 Nov 15.

Group on the Molecular and Cell Biology of Lipids and Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13881981140024
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http://dx.doi.org/10.1016/j.bbalip.2014.11.006DOI Listing
February 2015

Phosphatidic acid inhibits ceramide 1-phosphate-stimulated macrophage migration.

Biochem Pharmacol 2014 Dec 18;92(4):642-50. Epub 2014 Oct 18.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48080 Bilbao, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00062952140059
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http://dx.doi.org/10.1016/j.bcp.2014.10.005DOI Listing
December 2014

New insights on the role of ceramide 1-phosphate in inflammation.

Biochim Biophys Acta 2013 Jun 11;1831(6):1060-6. Epub 2013 Feb 11.

Department of Biochemistry and Molecular Biology, University of the Basque Country, Bilbao, Spain.

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http://dx.doi.org/10.1016/j.bbalip.2013.02.001DOI Listing
June 2013

Ceramide 1-phosphate induces macrophage chemoattractant protein-1 release: involvement in ceramide 1-phosphate-stimulated cell migration.

Am J Physiol Endocrinol Metab 2013 Jun 2;304(11):E1213-26. Epub 2013 Apr 2.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Bilbao, Spain.

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http://dx.doi.org/10.1152/ajpendo.00480.2012DOI Listing
June 2013

Ceramide 1-phosphate stimulates glucose uptake in macrophages.

Cell Signal 2013 Apr 16;25(4):786-95. Epub 2013 Jan 16.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48080 Bilbao, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S08986568130001
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http://dx.doi.org/10.1016/j.cellsig.2013.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904441PMC
April 2013

Ceramide 1-phosphate stimulates proliferation of C2C12 myoblasts.

Biochimie 2012 Mar 17;94(3):597-607. Epub 2011 Sep 17.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, 48080 Bilbao, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S03009084110035
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http://dx.doi.org/10.1016/j.biochi.2011.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314975PMC
March 2012

Generation of reactive oxygen species (ROS) is a key factor for stimulation of macrophage proliferation by ceramide 1-phosphate.

Exp Cell Res 2012 Feb 6;318(4):350-60. Epub 2011 Dec 6.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, 48080 Bilbao, Spain.

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http://dx.doi.org/10.1016/j.yexcr.2011.11.013DOI Listing
February 2012

Activation of mTOR and RhoA is a major mechanism by which Ceramide 1-phosphate stimulates macrophage proliferation.

Cell Signal 2011 Jan 18;23(1):27-34. Epub 2010 Aug 18.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, Bilbao, Spain.

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http://dx.doi.org/10.1016/j.cellsig.2010.08.001DOI Listing
January 2011

Ceramide-1-phosphate in cell survival and inflammatory signaling.

Adv Exp Med Biol 2010 ;688:118-30

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, P.O. Box 644, 48080 Bilbao, Spain.

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http://dx.doi.org/10.1007/978-1-4419-6741-1_8DOI Listing
November 2010

Control of metabolism and signaling of simple bioactive sphingolipids: Implications in disease.

Prog Lipid Res 2010 Oct 1;49(4):316-34. Epub 2010 Mar 1.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Bilbao, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S01637827100001
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http://dx.doi.org/10.1016/j.plipres.2010.02.004DOI Listing
October 2010

Activation of protein kinase C-alpha is essential for stimulation of cell proliferation by ceramide 1-phosphate.

FEBS Lett 2010 Feb 27;584(3):517-24. Epub 2009 Nov 27.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, Bilbao, Spain.

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http://dx.doi.org/10.1016/j.febslet.2009.11.086DOI Listing
February 2010

Ceramide and ceramide 1-phosphate in health and disease.

Lipids Health Dis 2010 Feb 5;9:15. Epub 2010 Feb 5.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), PO Box 644, 48080 Bilbao, Spain.

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http://dx.doi.org/10.1186/1476-511X-9-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828451PMC
February 2010

Distinct receptor-mediated activities in macrophages for natural ceramide-1-phosphate (C1P) and for phospho-ceramide analogue-1 (PCERA-1).

Mol Cell Endocrinol 2010 Jan 23;314(2):248-55. Epub 2009 May 23.

Department of Biochemistry, Life Sciences Institute, Tel-Aviv University, Tel-Aviv, Israel.

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http://linkinghub.elsevier.com/retrieve/pii/S030372070900273
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http://dx.doi.org/10.1016/j.mce.2009.05.007DOI Listing
January 2010

Caged ceramide 1-phosphate analogues: synthesis and properties.

J Org Chem 2009 Nov;74(22):8844-7

Department of Chemistry and Biochemistry, Queens College of The City University of New York, Flushing, New York 11367-1597, USA.

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http://dx.doi.org/10.1021/jo902076wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782442PMC
November 2009

Ceramide 1-phosphate inhibits serine palmitoyltransferase and blocks apoptosis in alveolar macrophages.

Biochim Biophys Acta 2009 Apr 7;1791(4):263-72. Epub 2009 Feb 7.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, 48080 Bilbao, Spain.

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http://dx.doi.org/10.1016/j.bbalip.2009.01.023DOI Listing
April 2009

Ceramide 1-phosphate (C1P) promotes cell migration Involvement of a specific C1P receptor.

Cell Signal 2009 Mar 12;21(3):405-12. Epub 2008 Nov 12.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, P.O. Box 644, 48080 Bilbao, Spain.

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http://dx.doi.org/10.1016/j.cellsig.2008.11.003DOI Listing
March 2009

Involvement of nitric oxide in the promotion of cell survival by ceramide 1-phosphate.

FEBS Lett 2008 Jun 27;582(15):2263-9. Epub 2008 May 27.

Department of Biochemistry and Molecular Biology, University of the Basque Country, Bilbao, Spain.

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http://dx.doi.org/10.1016/j.febslet.2008.05.027DOI Listing
June 2008

Implication of ceramide, ceramide 1-phosphate and sphingosine 1-phosphate in tumorigenesis.

Transl Oncogenomics 2008 Apr 10;3:81-98. Epub 2008 Apr 10.

Department of Biochemistry and Molecular Biology. Faculty of Science and Technology. University of the Basque Country. P.O. Box 644. 48080 - Bilbao (Spain).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022355PMC
April 2008

Ceramide 1-phosphate stimulates macrophage proliferation through activation of the PI3-kinase/PKB, JNK and ERK1/2 pathways.

Cell Signal 2008 Apr 17;20(4):726-36. Epub 2007 Dec 17.

Department of Biochemistry and Molecular Biology, University of the Basque Country, P.O. Box 644, 48080 Bilbao, Spain.

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http://dx.doi.org/10.1016/j.cellsig.2007.12.008DOI Listing
April 2008

Ceramide kinase and ceramide-1-phosphate.

Methods Enzymol 2007 ;434:265-92

Department of Biochemistry and Molecular Biology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA.

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http://dx.doi.org/10.1016/S0076-6879(07)34015-9DOI Listing
December 2007

Sphingosine-1-phosphate stimulates aldosterone secretion through a mechanism involving the PI3K/PKB and MEK/ERK 1/2 pathways.

J Lipid Res 2007 Oct 3;48(10):2264-74. Epub 2007 Jul 3.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, 48080, Bilbao, Spain.

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http://dx.doi.org/10.1194/jlr.M700291-JLR200DOI Listing
October 2007

Membrane regulation of the stress response from prokaryotic models to mammalian cells.

Ann N Y Acad Sci 2007 Oct 26;1113:40-51. Epub 2007 Jul 26.

Institute of Biochemistry, Biology Research Centre, Hungarian Academy of Sciences,Temesvari krt 62, H-6726, Szeged, Hungary.

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http://dx.doi.org/10.1196/annals.1391.027DOI Listing
October 2007

Investigation of interleukin 1beta-mediated regulation of NF-kappaB activation in colonic cells reveals divergence between PKB and PDK-transduced events.

Mol Cell Biochem 2007 Jun 30;300(1-2):113-27. Epub 2006 Nov 30.

Division of Gastroenterology, Faculty of Medicine, The Jack Bell Research Centre, 2660 Oak Street, Vancouver, BC, Canada.

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http://dx.doi.org/10.1007/s11010-006-9375-4DOI Listing
June 2007

4-HPR-mediated leukemia cell cytotoxicity is triggered by ceramide-induced mitochondrial oxidative stress and is regulated downstream by Bcl-2.

Free Radic Res 2007 May;41(5):591-601

Department of Cell Biology and Histology, Faculty of Medicine and Dentistry, University of the Basque Country, Barrio Sarriena s/n, Leioa, Bizkaia, Spain.

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http://dx.doi.org/10.1080/10715760701218558DOI Listing
May 2007

Ceramide 1-phosphate/ceramide, a switch between life and death.

Biochim Biophys Acta 2006 Dec 19;1758(12):2049-56. Epub 2006 May 19.

Department of Biochemistry and Molecular Biology, University of the Basque Country, P.O. Box 644, 48080-Bilbao, Spain.

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http://dx.doi.org/10.1016/j.bbamem.2006.05.011DOI Listing
December 2006

Curcumin mediates ceramide generation via the de novo pathway in colon cancer cells.

Carcinogenesis 2006 Aug 25;27(8):1636-44. Epub 2006 Feb 25.

The Jack Bell Research Centre, 2660 Oak Street, Vancouver, BC, Canada.

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http://dx.doi.org/10.1093/carcin/bgi371DOI Listing
August 2006

Sphingosine 1-phosphate: a novel stimulator of aldosterone secretion.

J Lipid Res 2006 Jun 22;47(6):1238-49. Epub 2006 Mar 22.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, 48080 Bilbao, Spain.

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http://dx.doi.org/10.1194/jlr.M500510-JLR200DOI Listing
June 2006

Coupling of two pools of P2X7 receptors to distinct intracellular signaling pathways in rat submandibular gland.

J Lipid Res 2006 Apr 16;47(4):705-14. Epub 2006 Jan 16.

Departamento de Bioquimica y Biologia Molecular, Facultad de Ciencias, Universidad del Pais Vasco, 48080 Bilbao, Spain.

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http://dx.doi.org/10.1194/jlr.M500408-JLR200DOI Listing
April 2006

Ceramide-1-phosphate promotes cell survival through activation of the phosphatidylinositol 3-kinase/protein kinase B pathway.

FEBS Lett 2005 Jul;579(17):3744-50

Department of Biochemistry and Molecular Biology, Faculty of Sciences, University of the Basque Country, P.O. Box 644, 48080 Bilbao, Spain.

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http://dx.doi.org/10.1016/j.febslet.2005.05.067DOI Listing
July 2005

Acid sphingomyelinase in macrophage apoptosis.

Curr Opin Lipidol 2004 Oct;15(5):531-7

Department of Medicine, University of British Columbia, Vancouver, Canada.

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October 2004

Angiotensin II-stimulated cortisol secretion is mediated by phospholipase D.

Mol Cell Endocrinol 2004 Jul;222(1-2):9-20

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, P.O. Box 644, 48080 Bilbao, Spain.

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http://linkinghub.elsevier.com/retrieve/pii/S030372070400213
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http://dx.doi.org/10.1016/j.mce.2004.05.006DOI Listing
July 2004

Ceramide-1-phosphate: a novel regulator of cell activation.

FEBS Lett 2004 Mar;562(1-3):5-10

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, Bilbao, Spain.

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http://dx.doi.org/10.1016/s0014-5793(04)00211-xDOI Listing
March 2004

Ceramide-1-phosphate blocks apoptosis through inhibition of acid sphingomyelinase in macrophages.

J Lipid Res 2004 Jan 1;45(1):99-105. Epub 2003 Oct 1.

Department of Biochemistry and Molecular Biology, University of the Basque Country, PO Box 644, 48080 Bilbao, Spain.

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http://dx.doi.org/10.1194/jlr.M300158-JLR200DOI Listing
January 2004

Regulation of phospholipase D by P2X7 receptors in submandibular ductal cells.

Cell Signal 2003 Oct;15(10):927-35

Laboratoire de Biochimie et de Biologie Cellulaire, Institut de Pharmacie C.P. 205/3, Campus Plaine, Université Libre de Bruxelles, Boulevard du Triomphe, Brussels B 1050, Belgium.

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http://dx.doi.org/10.1016/s0898-6568(03)00053-6DOI Listing
October 2003

Sphingosine-1-phosphate inhibits acid sphingomyelinase and blocks apoptosis in macrophages.

FEBS Lett 2003 Mar;539(1-3):56-60

Department of Biochemistry and Molecular Biology, University of the Basque Country, P.O. Box 644, 48080 Bilbao, Spain.

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http://dx.doi.org/10.1016/s0014-5793(03)00197-2DOI Listing
March 2003

Regulation of phospholipase D by muscarinic receptors in rat submandibular ductal cells.

Cell Signal 2003 Jan;15(1):103-13

Laboratoire de Biochimie et de Biologie Cellulaire, Institut de Pharmacie CP 205/3, Campus Plaine, Université Libre de Bruxelles, Boulevard du Triomphe, B 1050 Brussels, Belgium.

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http://dx.doi.org/10.1016/s0898-6568(02)00059-1DOI Listing
January 2003

Sphingosine-1-phosphate stimulates cortisol secretion.

FEBS Lett 2003 Jan;535(1-3):101-5

Department of Biochemistry and Molecular Biology, Faculty of Sciences, University of the Basque Country, P.O. Box 644, 48080 Bilbao, Spain.

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http://dx.doi.org/10.1016/s0014-5793(02)03882-6DOI Listing
January 2003

Activation of phospholipase D-2 by P2X(7) agonists in rat submandibular gland acini.

J Lipid Res 2002 Aug;43(8):1244-55

Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of the Basque Country, P.O. Box 644, 48080 Bilbao, Spain.

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August 2002