Antonio DiGiandomenico

Antonio DiGiandomenico

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Antonio DiGiandomenico

Antonio DiGiandomenico

Publications by authors named "Antonio DiGiandomenico"

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Frontline Science: Employing enzymatic treatment options for management of ocular biofilm-based infections.

J Leukoc Biol 2019 Jun 28;105(6):1099-1110. Epub 2019 Jan 28.

Department of Medicine, Division of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/JLB.4HI0918-364RRDOI Listing
June 2019

Treatment Efficacy of MEDI3902 in blood stream infection and acute pneumonia rabbit models.

Antimicrob Agents Chemother 2019 Jun 3. Epub 2019 Jun 3.

Division of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, University of California, San Francisco

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http://dx.doi.org/10.1128/AAC.00710-19DOI Listing
June 2019

Neutrophil Extracellular Traps Confine Pseudomonas aeruginosa Ocular Biofilms and Restrict Brain Invasion.

Cell Host Microbe 2019 Apr 28;25(4):526-536.e4. Epub 2019 Mar 28.

University of Calgary, Department of Physiology and Pharmacology, Calvin Phoebe & Joan Snyder Institute for Chronic Diseases, Cumming School of Medicine, Calgary, AB, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2019.02.007DOI Listing
April 2019

MEDI3902 Correlates of Protection against Severe Pseudomonas aeruginosa Pneumonia in a Rabbit Acute Pneumonia Model.

Antimicrob Agents Chemother 2018 05 26;62(5). Epub 2018 Apr 26.

Division of HIV, Infectious Diseases, and Global Medicine, Department of Medicine, University of California, San Francisco, San Francisco, California, USA

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http://aac.asm.org/lookup/doi/10.1128/AAC.02565-17
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http://dx.doi.org/10.1128/AAC.02565-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923159PMC
May 2018

Anti-Psl Targeting of Pseudomonas aeruginosa Biofilms for Neutrophil-Mediated Disruption.

Sci Rep 2017 11 22;7(1):16065. Epub 2017 Nov 22.

Department of Infectious Diseases, MedImmune, LLC, Gaithersburg, MD, 20878, USA.

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http://dx.doi.org/10.1038/s41598-017-16215-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700069PMC
November 2017

Bispecific antibody targets multiple Pseudomonas aeruginosa evasion mechanisms in the lung vasculature.

J Clin Invest 2017 Jun 2;127(6):2249-2261. Epub 2017 May 2.

Department of Physiology and Pharmacology, Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1172/JCI89652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451222PMC
June 2017

Environmentally Endemic Pseudomonas aeruginosa Strains with Mutations in lasR Are Associated with Increased Disease Severity in Corneal Ulcers.

mSphere 2016 Sep-Oct;1(5). Epub 2016 Sep 7.

Department of Surgery (Ophthalmology), Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.

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http://dx.doi.org/10.1128/mSphere.00140-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014915PMC
September 2016

Recombinant Salmonella Expressing Burkholderia mallei LPS O Antigen Provides Protection in a Murine Model of Melioidosis and Glanders.

PLoS One 2015 6;10(7):e0132032. Epub 2015 Jul 6.

Department of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, Virginia, United States of America; Department of Pediatrics, Emory University School of Medicine and Children's Hospital of Atlanta, Inc., Atlanta, Georgia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132032PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492786PMC
April 2016

Antibacterial monoclonal antibodies: the next generation?

Curr Opin Microbiol 2015 Oct 25;27:78-85. Epub 2015 Aug 25.

Department of Infectious Diseases, MedImmune, LLC, Gaithersburg, MD 20878, United States. Electronic address:

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http://dx.doi.org/10.1016/j.mib.2015.07.014DOI Listing
October 2015

Synthetic Enterobacterial Common Antigen (ECA) for the Development of a Universal Immunotherapy for Drug-Resistant Enterobacteriaceae.

Angew Chem Int Ed Engl 2015 Sep 24;54(37):10953-7. Epub 2015 Jul 24.

Complex Carbohydrate Research Center, The University of Georgia, 315 Riverbend Road, Athens, GA 30602 (USA).

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http://dx.doi.org/10.1002/anie.201505420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664081PMC
September 2015

The "genomic storm" induced by bacterial endotoxin is calmed by a nuclear transport modifier that attenuates localized and systemic inflammation.

PLoS One 2014 20;9(10):e110183. Epub 2014 Oct 20.

Immunotherapy Program at Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America; Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0110183PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203769PMC
July 2015

Epitope mapping of monoclonal antibodies using synthetic oligosaccharides uncovers novel aspects of immune recognition of the Psl exopolysaccharide of Pseudomonas aeruginosa.

Chemistry 2013 Dec 18;19(51):17425-31. Epub 2013 Nov 18.

Complex Carbohydrate Research Center, The University of Georgia, Athens, GA 30602 (USA).

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http://dx.doi.org/10.1002/chem.201302916DOI Listing
December 2013

Host derived inflammatory phospholipids regulate rahU (PA0122) gene, protein, and biofilm formation in Pseudomonas aeruginosa.

Cell Immunol 2011 5;270(2):95-102. Epub 2011 May 5.

Research Department, Carilion Clinic and Virginia Tech Carilion School of Medicine, Roanoke, VA 24013, USA.

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http://dx.doi.org/10.1016/j.cellimm.2011.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415270PMC
October 2011

Extended anti-inflammatory action of a degradation-resistant mutant of cell-penetrating suppressor of cytokine signaling 3.

J Biol Chem 2010 Jun 16;285(24):18727-36. Epub 2010 Apr 16.

Department of Microbiology and Immunology, Meharry Medical College, Nashville, Tennessee 37208, USA.

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http://dx.doi.org/10.1074/jbc.M109.095216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881796PMC
June 2010

Intracellular delivery of a cell-penetrating SOCS1 that targets IFN-gamma signaling.

Sci Signal 2009 Jul 21;2(80):ra37. Epub 2009 Jul 21.

Department of Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232-2363, USA.

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http://dx.doi.org/10.1126/scisignal.1162191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798805PMC
July 2009

Suppression of acute lung inflammation by intracellular peptide delivery of a nuclear import inhibitor.

Mol Ther 2009 May 3;17(5):796-802. Epub 2009 Mar 3.

Department of Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-2363, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S152500161631777
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http://dx.doi.org/10.1038/mt.2009.18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835128PMC
May 2009

Lipopolysaccharide O-antigen chain length regulation in Pseudomonas aeruginosa serogroup O11 strain PA103.

J Bacteriol 2008 Apr 7;190(8):2709-16. Epub 2007 Dec 7.

Department of Microbiology, University of Virginia Health System, Charlottesville, Virginia, USA.

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http://jb.asm.org/content/190/8/2709.full.pdf
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http://jb.asm.org/cgi/doi/10.1128/JB.01646-07
Publisher Site
http://dx.doi.org/10.1128/JB.01646-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2293223PMC
April 2008

A novel oxidized low-density lipoprotein-binding protein from Pseudomonas aeruginosa.

Microbiology 2008 Feb;154(Pt 2):654-65

Department of Microbiology, University of Virginia Health Sciences Center, Charlottesville, VA, USA.

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http://dx.doi.org/10.1099/mic.0.2007/011429-0DOI Listing
February 2008

Intranasal immunization with heterologously expressed polysaccharide protects against multiple Pseudomonas aeruginosa infections.

Proc Natl Acad Sci U S A 2007 Mar 5;104(11):4624-9. Epub 2007 Mar 5.

Department of Microbiology, University of Virginia Health System, 1300 Jefferson Avenue, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1073/pnas.0608657104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838651PMC
March 2007

Oral vaccination of BALB/c mice with Salmonella enterica serovar Typhimurium expressing Pseudomonas aeruginosa O antigen promotes increased survival in an acute fatal pneumonia model.

Infect Immun 2004 Dec;72(12):7012-21

Department of Microbiology, University of Virginia Health Sciences Center, Box 800734, 1300 Jefferson Park Avenue, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1128/IAI.72.12.7012-7021.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC529127PMC
December 2004

Glycosylation of Pseudomonas aeruginosa 1244 pilin: glycan substrate specificity.

Mol Microbiol 2002 Oct;46(2):519-30

Department of Biological Sciences, Duquesne University, Pittsburg, PA 15282, USA.

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October 2002