Publications by authors named "Antonio Del Sol"

85 Publications

Leveraging systems biology for predicting modulators of inflammation in patients with COVID-19.

Sci Adv 2021 02 3;7(6). Epub 2021 Feb 3.

Computational Biology Group, CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Bizkaia Technology Park, Derio 48160, Spain.

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February 2021

Corrigendum to: FunRes: resolving tissue-specific functional cell states based on a cell-cell communication network model.

Brief Bioinform 2021 Jan 29. Epub 2021 Jan 29.

Computational Biology Group, Luxembourg Centre for Systems Biomedicine (LCSB), Esch-sur-Alzette, L-4362, Luxembourg.

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January 2021

Computational Stem Cell Biology: Open Questions and Guiding Principles.

Cell Stem Cell 2021 Jan;28(1):20-32

Centre for Stem Cell Systems, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, VIC 3010, Australia.

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January 2021

FunRes: resolving tissue-specific functional cell states based on a cell-cell communication network model.

Brief Bioinform 2020 Nov 12. Epub 2020 Nov 12.

Luxembourg Centre for Systems Biology and Ikerbasque.

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November 2020

TransSynW: A single-cell RNA-sequencing based web application to guide cell conversion experiments.

Stem Cells Transl Med 2021 Feb 8;10(2):230-238. Epub 2020 Oct 8.

Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Belvaux, Luxembourg.

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February 2021

Multiomics data integration unveils core transcriptional regulatory networks governing cell-type identity.

NPJ Syst Biol Appl 2020 08 24;6(1):26. Epub 2020 Aug 24.

CIC bioGUNE, Bizkaia Technology Park, 48160, Derio, Spain.

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August 2020

The Importance of Computational Modeling in Stem Cell Research.

Trends Biotechnol 2021 02 13;39(2):126-136. Epub 2020 Aug 13.

CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Bizkaia Technology Park, 801 Building, 48160 Derio, Spain.

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February 2021

SigHotSpotter: scRNA-seq-based computational tool to control cell subpopulation phenotypes for cellular rejuvenation strategies.

Bioinformatics 2019 Nov 7. Epub 2019 Nov 7.

Computational Biology Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7, avenue des Hauts-Fourneaux, L-4362 Esch-sur-Alzette Luxembourg.

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November 2019

Modeling Cellular Differentiation and Reprogramming with Gene Regulatory Networks.

Methods Mol Biol 2019 ;1975:37-51

Computational Biology Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Luxembourg.

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September 2019

An integrative method to predict signalling perturbations for cellular transitions.

Nucleic Acids Res 2019 07;47(12):e72

Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette L-4362, Luxembourg.

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July 2019

A general computational approach to predicting synergistic transcriptional cores that determine cell subpopulation identities.

Nucleic Acids Res 2019 04;47(7):3333-3343

Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 6, avenue du Swing, L-4367 Belvaux, Luxembourg.

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April 2019

Computational Strategies for Niche-Dependent Cell Conversion to Assist Stem Cell Therapy.

Trends Biotechnol 2019 07 16;37(7):687-696. Epub 2019 Feb 16.

Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg,7 Avenue des Hauts-Fourneaux, Esch-sur-Alzette, L-4362 Luxembourg City, Luxembourg.

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July 2019

SeesawPred: A Web Application for Predicting Cell-fate Determinants in Cell Differentiation.

Sci Rep 2018 09 6;8(1):13355. Epub 2018 Sep 6.

Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7. avenue des Hauts-Fourneaux, Esch-sur-Alzette, L-4362, Luxembourg City, Luxembourg.

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September 2018

Transcriptional synergy as an emergent property defining cell subpopulation identity enables population shift.

Nat Commun 2018 07 3;9(1):2595. Epub 2018 Jul 3.

Computational Biology Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 6, avenue du Swing, L-4367, Belvaux, Luxembourg.

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July 2018

A complex of the ubiquitin ligase TRIM32 and the deubiquitinase USP7 balances the level of c-Myc ubiquitination and thereby determines neural stem cell fate specification.

Cell Death Differ 2019 03 13;26(4):728-740. Epub 2018 Jun 13.

Developmental and Cellular Biology Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4367, Belvaux, Luxembourg.

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March 2019

Signaling-Dependent Control of Apical Membrane Size and Self-Renewal in Rosette-Stage Human Neuroepithelial Stem Cells.

Stem Cell Reports 2018 06 17;10(6):1751-1765. Epub 2018 May 17.

Research Institute for Molecular Pathology (IMP), Vienna Biocenter (VBC), Campus-Vienna-Biocenter 1, 1030 Vienna, Austria; DFG Research Center for Regenerative Therapies, Technische Universität Dresden, Fetscherstraße 105, 01307 Dresden, Germany; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany.

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June 2018

Integrative Computational Network Analysis Reveals Site-Specific Mediators of Inflammation in Alzheimer's Disease.

Front Physiol 2018 2;9:154. Epub 2018 Mar 2.

Computational Biology Group, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Luxembourg, Luxembourg.

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March 2018

The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity.

Cell Rep 2018 01;22(2):396-410

Tumour Suppression Group, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain; Cellular Plasticity and Disease Group, Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST), Barcelona 08028, Spain; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona 08010, Spain. Electronic address:

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January 2018

Absence of regulator of G-protein signaling 4 does not protect against dopamine neuron dysfunction and injury in the mouse 6-hydroxydopamine lesion model of Parkinson's disease.

Neurobiol Aging 2017 10 19;58:30-33. Epub 2017 Jun 19.

Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette, Luxembourg. Electronic address:

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October 2017

Prediction of Chromatin Accessibility in Gene-Regulatory Regions from Transcriptomics Data.

Sci Rep 2017 07 5;7(1):4660. Epub 2017 Jul 5.

Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Belvaux, Luxembourg.

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July 2017