Antonio Del Sol

Luxembourg Centre for Systems Biomedicine (LCSB), Laboratory of Developmental and Cellular Biology, University of Luxembourg, Avenue du Swing 6, Belvaux, Luxembourg.

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December 2019

Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood.

Clin Epigenetics 2019 11 27;11(1):164. Epub 2019 Nov 27.

School for Mental Health and Neuroscience (MHeNS), Department of Psychiatry and Neuropsychology, Maastricht University, P.O. Box 616, 6200, MD, Maastricht, the Netherlands.

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November 2019

SigHotSpotter: scRNA-seq-based computational tool to control cell subpopulation phenotypes for cellular rejuvenation strategies.

Authors:

Srikanth Ravichandran András Hartmann Antonio Del Sol

Bioinformatics 2019 Nov 7. Epub 2019 Nov 7.

Computational Biology Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7, avenue des Hauts-Fourneaux, L-4362 Esch-sur-Alzette Luxembourg.

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November 2019

Integrative and perturbation-based analysis of the transcriptional dynamics of TGFβ/BMP system components in transition from embryonic stem cells to neural progenitors.

Authors:

Ruben Dries Agata Stryjewska Kathleen Coddens Satoshi Okawa Tineke Notelaers Judith Birkhoff Mike Dekker Catherine M Verfaillie Antonio Del Sol Eskeatnaf Mulugeta Andrea Conidi Frank G Grosveld Danny Huylebroeck

Stem Cells 2020 02 13;38(2):202-217. Epub 2019 Dec 13.

Department of Cell Biology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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February 2020

Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects.

Authors:

T Yvanka de Soysa Sanjeev S Ranade Satoshi Okawa Srikanth Ravichandran Yu Huang Hazel T Salunga Amelia Schricker Antonio Del Sol Casey A Gifford Deepak Srivastava

Nature 2019 08 24;572(7767):120-124. Epub 2019 Jul 24.

Gladstone Institute of Cardiovascular Disease, San Francisco, CA, USA.

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August 2019

Modeling Cellular Differentiation and Reprogramming with Gene Regulatory Networks.

Authors:

András Hartmann Srikanth Ravichandran Antonio Del Sol

Methods Mol Biol 2019 ;1975:37-51

Computational Biology Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-Belval, Luxembourg.

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September 2019

An integrative method to predict signalling perturbations for cellular transitions.

Authors:

Gaia Zaffaroni Satoshi Okawa Manuel Morales-Ruiz Antonio Del Sol

Nucleic Acids Res 2019 07;47(12):e72

Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette L-4362, Luxembourg.

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July 2019

Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain.

Cell 2019 03 28;176(6):1407-1419.e14. Epub 2019 Feb 28.

Molecular Neurobiology, German Cancer Research Center, 69120 Heidelberg, Germany. Electronic address:

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March 2019

A general computational approach to predicting synergistic transcriptional cores that determine cell subpopulation identities.

Authors:

Satoshi Okawa Antonio Del Sol

Nucleic Acids Res 2019 04;47(7):3333-3343

Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 6, avenue du Swing, L-4367 Belvaux, Luxembourg.

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April 2019

Computational Strategies for Niche-Dependent Cell Conversion to Assist Stem Cell Therapy.

Authors:

Antonio Del Sol Satoshi Okawa Srikanth Ravichandran

Trends Biotechnol 2019 07 16;37(7):687-696. Epub 2019 Feb 16.

Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg,7 Avenue des Hauts-Fourneaux, Esch-sur-Alzette, L-4362 Luxembourg City, Luxembourg.

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July 2019

SeesawPred: A Web Application for Predicting Cell-fate Determinants in Cell Differentiation.

Authors:

András Hartmann Satoshi Okawa Gaia Zaffaroni Antonio Del Sol

Sci Rep 2018 09 6;8(1):13355. Epub 2018 Sep 6.

Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7. avenue des Hauts-Fourneaux, Esch-sur-Alzette, L-4362, Luxembourg City, Luxembourg.

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September 2018

Transcriptional synergy as an emergent property defining cell subpopulation identity enables population shift.

Authors:

Satoshi Okawa Carmen Saltó Srikanth Ravichandran Shanzheng Yang Enrique M Toledo Ernest Arenas Antonio Del Sol

Nat Commun 2018 07 3;9(1):2595. Epub 2018 Jul 3.

Computational Biology Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 6, avenue du Swing, L-4367, Belvaux, Luxembourg.

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July 2018

A complex of the ubiquitin ligase TRIM32 and the deubiquitinase USP7 balances the level of c-Myc ubiquitination and thereby determines neural stem cell fate specification.

Authors:

Sarah Nicklas Anna-Lena Hillje Satoshi Okawa Ina-Maria Rudolph Franziska Melanie Collmann Thea van Wuellen Antonio Del Sol Jens C Schwamborn

Cell Death Differ 2019 03 13;26(4):728-740. Epub 2018 Jun 13.

Developmental and Cellular Biology Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, L-4367, Belvaux, Luxembourg.

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March 2019

Signaling-Dependent Control of Apical Membrane Size and Self-Renewal in Rosette-Stage Human Neuroepithelial Stem Cells.

Authors:

Jan-Philip Medelnik Kathleen Roensch Satoshi Okawa Antonio Del Sol Osvaldo Chara Levan Mchedlishvili Elly M Tanaka

Stem Cell Reports 2018 06 17;10(6):1751-1765. Epub 2018 May 17.

Research Institute for Molecular Pathology (IMP), Vienna Biocenter (VBC), Campus-Vienna-Biocenter 1, 1030 Vienna, Austria; DFG Research Center for Regenerative Therapies, Technische Universität Dresden, Fetscherstraße 105, 01307 Dresden, Germany; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany.

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June 2018

Loss of inter-cellular cooperation by complete epithelial-mesenchymal transition supports favorable outcomes in basal breast cancer patients.

Authors:

Anne Grosse-Wilde Rolf E Kuestner Stephanie M Skelton Ellie MacIntosh Aymeric Fouquier d'Hérouël Gökhan Ertaylan Antonio Del Sol Alexander Skupin Sui Huang

Oncotarget 2018 Apr 13;9(28):20018-20033. Epub 2018 Apr 13.

Institute for Systems Biology, Seattle, WA, USA.

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April 2018

Integrative Computational Network Analysis Reveals Site-Specific Mediators of Inflammation in Alzheimer's Disease.

Authors:

Srikanth Ravichandran Alessandro Michelucci Antonio Del Sol

Front Physiol 2018 2;9:154. Epub 2018 Mar 2.

Computational Biology Group, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Luxembourg, Luxembourg.

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March 2018

Regulation of Fn14 Receptor and NF-κB Underlies Inflammation in Meniere's Disease.

Front Immunol 2017 13;8:1739. Epub 2017 Dec 13.

Otology and Neurotology Group CTS495, Department of Genomic Medicine - Centre for Genomics and Oncological Research - Pfizer/Universidad de Granada/Junta de Andalucía (GENYO), Granada, Spain.

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December 2017

The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity.

Authors:

Cian J Lynch Raquel Bernad Isabel Calvo Sandrina Nóbrega-Pereira Sergio Ruiz Nuria Ibarz Ana Martinez-Val Osvaldo Graña-Castro Gonzalo Gómez-López Eduardo Andrés-León Vladimir Espinosa Angarica Antonio Del Sol Sagrario Ortega Oscar Fernandez-Capetillo Enrique Rojo Javier Munoz Manuel Serrano

Cell Rep 2018 01;22(2):396-410

Tumour Suppression Group, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain; Cellular Plasticity and Disease Group, Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST), Barcelona 08028, Spain; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona 08010, Spain. Electronic address:

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January 2018