Antonio Bastone

V363I and V363A mutated tau affect aggregation and neuronal dysfunction differently in C. elegans.

Authors:

Federica Morelli Margherita Romeo Maria Monica Barzago Marco Bolis Davide Mattioni Giacomina Rossi Fabrizio Tagliavini Antonio Bastone Mario Salmona Luisa Diomede

Neurobiol Dis 2018 09 22;117:226-234. Epub 2018 Jun 22.

Department of Molecular Biochemistry and Pharmacology, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milano, Italy. Electronic address:

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September 2018

A simple headspace gas chromatography/mass spectrometry method for the quantitative determination of the release of the antioxidants butylated hydroxyanisole and butylated hydroxytoluene from chewing gum.

Authors:

Enrico Davoli Antonio Bastone Giancarlo Bianchi Mario Salmona Luisa Diomede

Rapid Commun Mass Spectrom 2017 May;31(10):859-864

Department of Molecular Biochemistry and Pharmacology, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Via G. La Masa 19, 20156, Milan, Italy.

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May 2017

Mesenchymal stromal cell-secreted chemerin is a novel immunomodulatory molecule driving the migration of ChemR23-expressing cells.

Authors:

Paola Vinci Antonio Bastone Silvia Schiarea Claudia Cappuzzello Annalisa Del Prete Erica Dander Andrea Biondi Giovanna D'Amico

Cytotherapy 2017 02 6;19(2):200-210. Epub 2016 Dec 6.

Centro di Ricerca Tettamanti, Clinica Pediatrica, Università di Milano-Bicocca, Monza, Italy. Electronic address:

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February 2017

NO-donor thiacarbocyanines as multifunctional agents for Alzheimer's disease.

Authors:

Konstantin Chegaev Antonella Federico Elisabetta Marini Barbara Rolando Roberta Fruttero Michela Morbin Giacomina Rossi Valeria Fugnanesi Antonio Bastone Mario Salmona Nahuai B Badiola Laura Gasparini Sara Cocco Cristian Ripoli Claudio Grassi Alberto Gasco

Bioorg Med Chem 2015 Aug 3;23(15):4688-4698. Epub 2015 Jun 3.

Dipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, via Pietro Giuria 9, 10125 Torino, Italy.

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August 2015

An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode.

J Exp Med 2015 Jun 11;212(6):905-25. Epub 2015 May 11.

Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Humanitas Clinical and Research Center, 20089 Milan, Italy Humanitas University, 20089 Milan, Italy

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June 2015

A new surface plasmon resonance-based immunoassay for rapid, reproducible and sensitive quantification of pentraxin-3 in human plasma.

Authors:

Mara Canovi Jacopo Lucchetti Matteo Stravalaci Sonia Valentino Barbara Bottazzi Mario Salmona Antonio Bastone Marco Gobbi

Sensors (Basel) 2014 Jun 19;14(6):10864-75. Epub 2014 Jun 19.

Department of Biochemistry and Molecular Pharmacology, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milan 20156, Italy.

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June 2014

Expression of A2V-mutated Aβ in Caenorhabditis elegans results in oligomer formation and toxicity.

Authors:

Luisa Diomede Giuseppe Di Fede Margherita Romeo Renzo Bagnati Roberta Ghidoni Fabio Fiordaliso Monica Salio Alessandro Rossi Marcella Catania Anna Paterlini Luisa Benussi Antonio Bastone Matteo Stravalaci Marco Gobbi Fabrizio Tagliavini Mario Salmona

Neurobiol Dis 2014 Feb 1;62:521-32. Epub 2013 Nov 1.

Department of Molecular Biochemistry and Pharmacology, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Via La Masa 19, 20156 Milan, Italy.

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February 2014

Different mutations at V363 MAPT codon are associated with atypical clinical phenotypes and show unusual structural and functional features.

Authors:

Giacomina Rossi Antonio Bastone Elena Piccoli Michela Morbin Giulia Mazzoleni Valeria Fugnanesi Marten Beeg Elena Del Favero Laura Cantù Simona Motta Ettore Salsano Davide Pareyson Alessandra Erbetta Antonio Emanuele Elia Francesca Del Sorbo Vincenzo Silani Claudia Morelli Mario Salmona Fabrizio Tagliavini

Neurobiol Aging 2014 Feb 7;35(2):408-17. Epub 2013 Sep 7.

Division of Neurology V and Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy. Electronic address:

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February 2014

Epitope scanning indicates structural differences in brain-derived monomeric and aggregated mutant prion proteins related to genetic prion diseases.

Authors:

Laura Tapella Matteo Stravalaci Antonio Bastone Emiliano Biasini Marco Gobbi Roberto Chiesa

Biochem J 2013 Sep;454(3):417-25

Dulbecco Telethon Institute c/o Department of Neuroscience, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Milano 20156, Italy.

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September 2013

Specific recognition of biologically active amyloid-β oligomers by a new surface plasmon resonance-based immunoassay and an in vivo assay in Caenorhabditis elegans.

Authors:

Matteo Stravalaci Antonio Bastone Marten Beeg Alfredo Cagnotto Laura Colombo Giuseppe Di Fede Fabrizio Tagliavini Laura Cantù Elena Del Favero Michele Mazzanti Roberto Chiesa Mario Salmona Luisa Diomede Marco Gobbi

J Biol Chem 2012 Aug 26;287(33):27796-805. Epub 2012 Jun 26.

Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri, 20156 Milan, Italy.

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August 2012

New mutations in MAPT gene causing frontotemporal lobar degeneration: biochemical and structural characterization.

Authors:

Giacomina Rossi Antonio Bastone Elena Piccoli Giulia Mazzoleni Michela Morbin Andrea Uggetti Giorgio Giaccone Sarah Sperber Marten Beeg Mario Salmona Fabrizio Tagliavini

Neurobiol Aging 2012 Apr 22;33(4):834.e1-6. Epub 2011 Sep 22.

Division of Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.

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April 2012

Human C-type lectin domain family 4, member C (CLEC4C/BDCA-2/CD303) is a receptor for asialo-galactosyl-oligosaccharides.

Authors:

Elena Riboldi Roberta Daniele Carmen Parola Antonio Inforzato Phoebe L Arnold Daniela Bosisio Daved H Fremont Antonio Bastone Marco Colonna Silvano Sozzani

J Biol Chem 2011 Oct 31;286(41):35329-33. Epub 2011 Aug 31.

Dipartimento di Scienze Biomediche e Biotecnologie, Università degli Studi di Brescia, Viale Europa 11, 25123 Brescia, Italy.

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October 2011

A modified protocol to prepare seed-free starting solutions of amyloid-β (Aβ)₁₋₄₀ and Aβ₁₋₄₂ from the corresponding depsipeptides.

Authors:

Marten Beeg Matteo Stravalaci Antonio Bastone Mario Salmona Marco Gobbi

Anal Biochem 2011 Apr 24;411(2):297-9. Epub 2010 Dec 24.

Department of Biochemistry and Molecular Pharmacology, Instituto di Ricerche Farmacologiche "Mario Negri", 20156 Milano, Italy.

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April 2011

Evolution of the pentraxin family: the new entry PTX4.

Authors:

Yeny Martinez de la Torre Marco Fabbri Sebastien Jaillon Antonio Bastone Manuela Nebuloni Annunciata Vecchi Alberto Mantovani Cecilia Garlanda

J Immunol 2010 May 31;184(9):5055-64. Epub 2010 Mar 31.

Laboratorio di Immunologia e Infiammazione, Istituto Clinico Humanitas, Istituto Di Ricovero e Cura a Carattere Scientifico, Rozzano.

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May 2010

Regulation of leukocyte recruitment by the long pentraxin PTX3.

Nat Immunol 2010 Apr 7;11(4):328-34. Epub 2010 Mar 7.

Laboratory for Immunology and Inflammation, Instituto di Ricovero e Cura a Carattere Scientifico-Istituto Clinico Humanitas, Rozzano, Italy.

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April 2010

Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein.

Authors:

Claudia Balducci Marten Beeg Matteo Stravalaci Antonio Bastone Alessandra Sclip Emiliano Biasini Laura Tapella Laura Colombo Claudia Manzoni Tiziana Borsello Roberto Chiesa Marco Gobbi Mario Salmona Gianluigi Forloni

Proc Natl Acad Sci U S A 2010 Feb 19;107(5):2295-300. Epub 2010 Jan 19.

Department of Neuroscience, Mario Negri Institute for Pharmacological Research, Milan 20156, Italy.

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February 2010

Proteomic profiling of cervical and lumbar spinal cord reveals potential protective mechanisms in the wobbler mouse, a model of motor neuron degeneration.

Authors:

Antonio Bastone Elena Fumagalli Paolo Bigini Pietro Perini Davide Bernardinello Alfredo Cagnotto Ilario Mereghetti Daniela Curti Mario Salmona Tiziana Mennini

J Proteome Res 2009 Nov;8(11):5229-40

Department of Biochemistry and Molecular Pharmacology, Mario Negri Institute for Pharmacological Research, Milano, Italy.

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November 2009

Synergy between ficolin-2 and pentraxin 3 boosts innate immune recognition and complement deposition.

Authors:

Ying Jie Ma Andrea Doni Tina Hummelshøj Christian Honoré Antonio Bastone Alberto Mantovani Nicole M Thielens Peter Garred

J Biol Chem 2009 Oct 24;284(41):28263-75. Epub 2009 Jul 24.

Laboratory of Molecular Medicine, Department of Clinical Immunology, Section 7631, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen 2100, Denmark.

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October 2009

A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis.

Science 2009 Mar;323(5920):1473-7

Division of Neurology and Neuropathology, "Carlo Besta" National Neurological Institute, 20133 Milan, Italy.

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March 2009

JNK regulates APP cleavage and degradation in a model of Alzheimer's disease.

Authors:

Alessio Colombo Antonio Bastone Cristina Ploia Alessandra Sclip Mario Salmona Gianluigi Forloni Tiziana Borsello

Neurobiol Dis 2009 Mar 8;33(3):518-25. Epub 2009 Jan 8.

Istituto di Ricerche Farmacologiche Mario Negri, Via La Masa 19, 20156 Milano, Italy.

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March 2009

Binding of the long pentraxin PTX3 to factor H: interacting domains and function in the regulation of complement activation.

Authors:

Livija Deban Hanna Jarva Markus J Lehtinen Barbara Bottazzi Antonio Bastone Andrea Doni T Sakari Jokiranta Alberto Mantovani Seppo Meri

J Immunol 2008 Dec;181(12):8433-40

Laboratory for Immunology and Inflammation, Instituto di Ricerca e Cura a Carattere Scientifico Istituto Clinico Humanitas, Rozzano, Italy.

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December 2008

Role of the molybdoflavoenzyme aldehyde oxidase homolog 2 in the biosynthesis of retinoic acid: generation and characterization of a knockout mouse.

Authors:

Mineko Terao Mami Kurosaki Maria Monica Barzago Maddalena Fratelli Renzo Bagnati Antonio Bastone Chiara Giudice Eugenio Scanziani Alessandra Mancuso Cecilia Tiveron Enrico Garattini

Mol Cell Biol 2009 Jan 3;29(2):357-77. Epub 2008 Nov 3.

Laboratory of Molecular Biology, Department of Biochemistry and Molecular Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri, via La Masa 19, 20156 Milan, Italy.

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January 2009

Structural characterization of PTX3 disulfide bond network and its multimeric status in cumulus matrix organization.

Authors:

Antonio Inforzato Vincenzo Rivieccio Antonio P Morreale Antonio Bastone Antonietta Salustri Laura Scarchilli Antonio Verdoliva Silvia Vincenti Grazia Gallo Caterina Chiapparino Lucrezia Pacello Eleonora Nucera Ottaviano Serlupi-Crescenzi Anthony J Day Barbara Bottazzi Alberto Mantovani Rita De Santis Giovanni Salvatori

J Biol Chem 2008 Apr 25;283(15):10147-61. Epub 2008 Jan 25.

Sigma-Tau Research and Development, Via Pontina km 30.400, Pomezia, Italy.

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April 2008

PTX3 interacts with inter-alpha-trypsin inhibitor: implications for hyaluronan organization and cumulus oophorus expansion.

Authors:

Laura Scarchilli Antonella Camaioni Barbara Bottazzi Veronica Negri Andrea Doni Livija Deban Antonio Bastone Giovanni Salvatori Alberto Mantovani Gregorio Siracusa Antonietta Salustri

J Biol Chem 2007 Oct 2;282(41):30161-70. Epub 2007 Aug 2.

Department of Public Health and Cell Biology, University of Rome Tor Vergata, 00133 Rome.

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October 2007

Structure and function of the long pentraxin PTX3 glycosidic moiety: fine-tuning of the interaction with C1q and complement activation.

Authors:

Antonio Inforzato Giuseppe Peri Andrea Doni Cecilia Garlanda Alberto Mantovani Antonio Bastone Andrea Carpentieri Angela Amoresano Piero Pucci Anja Roos Mohamed R Daha Silvia Vincenti Grazia Gallo Paolo Carminati Rita De Santis Giovanni Salvatori

Biochemistry 2006 Sep;45(38):11540-51

Department of Biology, University Tor Vergata, Rome, Italy.

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September 2006

Identification of an antiangiogenic FGF2-binding site in the N terminus of the soluble pattern recognition receptor PTX3.

Authors:

Maura Camozzi Marco Rusnati Antonella Bugatti Barbara Bottazzi Alberto Mantovani Antonio Bastone Antonio Inforzato Silvia Vincenti Luisa Bracci Domenico Mastroianni Marco Presta

J Biol Chem 2006 Aug 12;281(32):22605-13. Epub 2006 Jun 12.

Unit of General Pathology and Immunology, Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, 25123 Brescia, Italy.

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August 2006

Avian and canine aldehyde oxidases. Novel insights into the biology and evolution of molybdo-flavoenzymes.

Authors:

Mineko Terao Mami Kurosaki Maria Monica Barzago Emanuela Varasano Andrea Boldetti Antonio Bastone Maddalena Fratelli Enrico Garattini

J Biol Chem 2006 Jul 3;281(28):19748-61. Epub 2006 May 3.

Laboratory of Molecular Biology, Centro Catullo e Daniela Borgomainerio, Istituto di Ricerche Farmacologiche Mario Negri, via Eritrea 62, 20157 Milano, Italy.

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July 2006

The long pentraxin PTX3 as a link among innate immunity, inflammation, and female fertility.

Authors:

Barbara Bottazzi Antonio Bastone Andrea Doni Cecilia Garlanda Sonia Valentino Livija Deban Virginia Maina Alessia Cotena Federica Moalli Luca Vago Antonietta Salustri Luigina Romani Alberto Mantovani

J Leukoc Biol 2006 May 14;79(5):909-12. Epub 2006 Feb 14.

Istituto Clinico Humanitas, Rozzano, Milan, Italy.

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May 2006

Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility.

Authors:

Cecilia Garlanda Barbara Bottazzi Antonio Bastone Alberto Mantovani

Annu Rev Immunol 2005 ;23:337-66

Istituto di Ricerche Farmacologiche Mario Negri, 20157 Milan, Italy.

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June 2005

The aldehyde oxidase gene cluster in mice and rats. Aldehyde oxidase homologue 3, a novel member of the molybdo-flavoenzyme family with selective expression in the olfactory mucosa.

Authors:

Mami Kurosaki Mineko Terao Maria Monica Barzago Antonio Bastone Davide Bernardinello Mario Salmona Enrico Garattini

J Biol Chem 2004 Nov 20;279(48):50482-98. Epub 2004 Sep 20.

Laboratory of Molecular Biology, Centro Catullo e Daniela Borgomainerio, Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy.

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November 2004

PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization.

Authors:

Antonietta Salustri Cecilia Garlanda Emilio Hirsch Marika De Acetis Alessia Maccagno Barbara Bottazzi Andrea Doni Antonio Bastone Giovanna Mantovani Paolo Beck Peccoz Giovanni Salvatori David J Mahoney Anthony J Day Gregorio Siracusa Luigina Romani Alberto Mantovani

Development 2004 Apr 3;131(7):1577-86. Epub 2004 Mar 3.

Department of Public Health and Cell Biology, University of Rome Tor Vergata, Rome 00133, Italy.

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April 2004

Regulation and biochemistry of mouse molybdo-flavoenzymes. The DBA/2 mouse is selectively deficient in the expression of aldehyde oxidase homologues 1 and 2 and represents a unique source for the purification and characterization of aldehyde oxidase.

Authors:

Ruth Vila Mami Kurosaki Maria Monica Barzago Metodej Kolek Antonio Bastone Laura Colombo Mario Salmona Mineko Terao Enrico Garattini

J Biol Chem 2004 Mar 9;279(10):8668-83. Epub 2003 Dec 9.

Department of Biochemistry and Molecular Pharmacology, Istituto di Ricerche Farmacologiche, "Mario Negri," via Eritrea, 62, Milano 20157, Italy.

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March 2004

Long pentraxin PTX3 upregulates tissue factor expression in human endothelial cells: a novel link between vascular inflammation and clotting activation.

Authors:

Emanuela Napoleone Angelomaria Di Santo Antonio Bastone Giuseppe Peri Alberto Mantovani Giovanni de Gaetano Maria Benedetta Donati Roberto Lorenzet

Arterioscler Thromb Vasc Biol 2002 May;22(5):782-7

Antonio Taticchi Unit for Atherosclerosis and Thrombosis, Department of Vascular Medicine and Pharmacology, Istituto Ricerche Farmacologiche Mario Negri, Consorzio Mario Negri Sud, S. Maria Imbaro, Italy.

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May 2002

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