Antonia R Sepulveda

Antonia R Sepulveda

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Antonia R Sepulveda

Antonia R Sepulveda

Publications by authors named "Antonia R Sepulveda"

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Testing algorithm for identification of patients with TRK fusion cancer.

J Clin Pathol 2019 Jul 9;72(7):460-467. Epub 2019 May 9.

Department of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1136/jclinpath-2018-205679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589488PMC
July 2019

Downregulation of () follows the stepwise progression to gastric adenocarcinoma.

Oncotarget 2019 Jun 11;10(39):3852-3864. Epub 2019 Jun 11.

Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.

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http://dx.doi.org/10.18632/oncotarget.26974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570468PMC
June 2019

Utilization Rate of Helicobacter pylori Immunohistochemistry Is Not Associated With the Diagnostic Rate of Helicobacter pylori Infection.

Appl Immunohistochem Mol Morphol 2018 Nov 28. Epub 2018 Nov 28.

Department of Pathology and Cell Biology.

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http://dx.doi.org/10.1097/PAI.0000000000000680DOI Listing
November 2018

HER2 Heterogeneity in Gastroesophageal Cancer Detected by Testing Biopsy and Resection Specimens.

Arch Pathol Lab Med 2018 Apr 7;142(4):516-522. Epub 2017 Aug 7.

From the Department of Pathology and Cell Biology, Columbia University Medical Center, New York Presbyterian Hospital, New York.

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http://dx.doi.org/10.5858/arpa.2017-0039-OADOI Listing
April 2018

AGA White Paper: Optimizing Endoscopic Ultrasound-Guided Tissue Acquisition and Future Directions.

Clin Gastroenterol Hepatol 2018 03 23;16(3):318-327. Epub 2017 Oct 23.

Division of Gastroenterology and Hepatology, Ochsner Medical Center, New Orleans, Louisiana.

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https://linkinghub.elsevier.com/retrieve/pii/S15423565173124
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http://dx.doi.org/10.1016/j.cgh.2017.10.020DOI Listing
March 2018

Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and the American Society of Clinical Oncology.

J Clin Oncol 2017 May 6;35(13):1453-1486. Epub 2017 Feb 6.

Antonia R. Sepulveda, Columbia University, New York, NY; Stanley R. Hamilton, Scott E. Kopetz, and Bruce D. Minsky, University of Texas MD Anderson Cancer Center, Houston, TX; Carmen J. Allegra, University of Florida Medical Center, Gainesville, FL; Wayne Grody, UCLA Medical Center, Los Angeles, CA; Allison M. Cushman-Vokoun, University of Nebraska Medical Center, Omaha, NE; William K. Funkhouser, University of North Carolina School of Medicine, Chapel Hill, NC; Christopher Lieu, University of Colorado Denver School of Medicine, Denver, CO; Noralane M. Lindor, Mayo Clinic, Scottsdale, AZ; Federico A. Monzon, Castle Biosciences, Friendswood, TX; Daniel J. Sargent, Mayo Clinic, Rochester, MN; Veena M. Singh, Biocept, San Diego, CA; Joseph Willis, Case Western Reserve University, Cleveland, OH; Jennifer Clark, American Society for Clinical Pathology, Washington, DC; Carol Colasacco and Christina B. Ventura, College of American Pathologists, Northfield, IL; R. Bryan Rumble, American Society of Clinical Oncology, Alexandria, VA; Robyn Temple-Smolkin, Association for Molecular Pathology, Bethesda, MD; and Jan A. Nowak, Roswell Park Cancer Institute, Buffalo, NY.

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http://dx.doi.org/10.1200/JCO.2016.71.9807DOI Listing
May 2017

Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline Summary From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and American Society of Clinical Oncology.

J Oncol Pract 2017 05 28;13(5):333-337. Epub 2017 Mar 28.

Columbia University, New York; Roswell Park Cancer Institute, Buffalo, NY; University of Texas MD Anderson Cancer Center, Houston; Castle Biosciences, Friendswood, TX; University of Florida Medical Center, Gainesville, FL; University of California Los Angeles Medical Center, Los Angeles; Biocept, San Diego, CA; University of Nebraska Medical Center, Omaha, NE; University of North Carolina School of Medicine, Chapel Hill, NC; University of Colorado Denver School of Medicine, Denver, CO; Mayo Clinic, Scottsdale, AZ; Mayo Clinic, Rochester, MN; Case Western Reserve University, Cleveland, OH; American Society for Clinical Pathology, Washington, DC; College of American Pathologists, Northfield, IL; American Society of Clinical Oncology, Alexandria, VA; and Association for Molecular Pathology, Bethesda, MD.

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http://dx.doi.org/10.1200/JOP.2017.022152DOI Listing
May 2017

Oesophageal adenocarcinoma and gastric cancer: should we mind the gap?

Nat Rev Cancer 2016 04;16(5):305-18

Division of Digestive and Liver Diseases and Herbert Irving Cancer Research Center, Columbia University College of Physicians and Surgeons, 1130 St Nicholas Avenue, New York, New York 10032, USA.

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http://dx.doi.org/10.1038/nrc.2016.24DOI Listing
April 2016

Hepatocellular adenoma classification: a comparative evaluation of immunohistochemistry and targeted mutational analysis.

Diagn Pathol 2016 Mar 9;11:27. Epub 2016 Mar 9.

Department of Pathology and Cell Biology, Columbia University Medical Center, 630 W 168th Street, VC14-238, New York, NY, 10032, USA.

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http://dx.doi.org/10.1186/s13000-016-0475-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784347PMC
March 2016

Mutational analysis by next generation sequencing of gastric type dysplasia occurring in hyperplastic polyps of the stomach: Mutations in gastric hyperplastic polyps.

Exp Mol Pathol 2015 Dec 29;99(3):468-73. Epub 2015 Aug 29.

Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, United States.

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http://dx.doi.org/10.1016/j.yexmp.2015.08.014DOI Listing
December 2015

The Cancer Genomics Resource List 2014.

Arch Pathol Lab Med 2015 Aug 1;139(8):989-1008. Epub 2014 Dec 1.

From the Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee (Dr Zutter); the Department of Pathology, Clarient Diagnostic Services, Aliso Viejo, California (Dr Bloom); the Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis (Dr Cheng); the Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri (Drs Hagemann and Pfeifer); Surveys, College of American Pathologists, Northfield, Illinois (Dr Kaufman); the Department of Pathology, Emory University, Atlanta, Georgia (Dr Krasinskas); the Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston (Dr Lazar); the Department of Pathology and Laboratory Medicine, Fletcher Allen Health Care, Burlington, Vermont (Dr Leonard); the Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts (Dr Lindeman); the Department of Pathology, Mayo Clinic, Rochester, Minnesota (Dr Moyer); Molecular and Genomic Pathology Laboratory, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (Dr Nikiforova); the Department of Pathology, NorthShore University Health System, Evanston, Illinois (Dr Nowak); the Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York (Dr Sepulveda); the Department of Pathology, Case Medical Center/Case Western Reserve University, Cleveland, Ohio (Dr Willis); and the Department of Molecular Pathology and Hematopathology, University of Minnesota, Minneapolis (Dr Yohe).

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http://dx.doi.org/10.5858/arpa.2014-0330-CPDOI Listing
August 2015

Molecular and histologic considerations in the assessment of serrated polyps.

Arch Pathol Lab Med 2015 Jun;139(6):730-41

From the Department of Pathology and Cell Biology, Columbia University, New York, New York.

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http://dx.doi.org/10.5858/arpa.2014-0424-RADOI Listing
June 2015

Mesothelin expression in pancreatic mucinous cysts.

Am J Clin Pathol 2014 Sep;142(3):313-9

From the Departments of Pathology and Laboratory Medicine and

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http://dx.doi.org/10.1309/AJCPDTTL2I5ECMFGDOI Listing
September 2014

H. pylori infection is associated with DNA damage of Lgr5-positive epithelial stem cells in the stomach of patients with gastric cancer.

Dig Dis Sci 2013 Jan 4;58(1):140-9. Epub 2012 Sep 4.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 3400 Spruce Street, Founders 6, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1007/s10620-012-2360-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816997PMC
January 2013

Math1/Atoh1 contributes to intestinalization of esophageal keratinocytes by inducing the expression of Muc2 and Keratin-20.

Dig Dis Sci 2012 Apr 7;57(4):845-57. Epub 2011 Dec 7.

Department of Medicine, Division of Gastroenterology, University of Pennsylvania, 650 CRB 415 Curie Blvd., Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1007/s10620-011-1998-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407817PMC
April 2012

Loss of transcription factor KLF5 in the context of p53 ablation drives invasive progression of human squamous cell cancer.

Cancer Res 2011 Oct 25;71(20):6475-84. Epub 2011 Aug 25.

Department of Medicine, Gastroenterology Division, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-1702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193554PMC
October 2011

LIN28B promotes colon cancer progression and metastasis.

Cancer Res 2011 Jun 21;71(12):4260-8. Epub 2011 Apr 21.

Gastroenterology Division and Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-4637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117110PMC
June 2011

Crohn's disease activity index does not correlate with endoscopic recurrence one year after ileocolonic resection.

Inflamm Bowel Dis 2011 Jan;17(1):118-26

Inflammatory Bowel Disease Center and Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1002/ibd.21355DOI Listing
January 2011

CpG methylation and reduced expression of O6-methylguanine DNA methyltransferase is associated with Helicobacter pylori infection.

Gastroenterology 2010 May 4;138(5):1836-44. Epub 2010 Jan 4.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1053/j.gastro.2009.12.042DOI Listing
May 2010

Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.

J Leukoc Biol 2009 Sep 19;86(3):633-43. Epub 2009 May 19.

Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1189/jlb.1008662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735284PMC
September 2009

Gastrointestinal hyperplasia with altered expression of DNA polymerase beta.

PLoS One 2009 Aug 5;4(8):e6493. Epub 2009 Aug 5.

Cellular and Molecular Pathology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0006493PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716528PMC
August 2009

CpG methylation analysis--current status of clinical assays and potential applications in molecular diagnostics: a report of the Association for Molecular Pathology.

J Mol Diagn 2009 Jul 18;11(4):266-78. Epub 2009 Jun 18.

Methylation Working Group of the Association for Molecular Pathology Clinical Practice Committee, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.2353/jmoldx.2009.080125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710701PMC
July 2009

MicroRNA expression profiling outperforms mRNA expression profiling in formalin-fixed paraffin-embedded tissues.

Int J Clin Exp Pathol 2009 Mar 20;2(6):519-27. Epub 2009 Mar 20.

Department of Pathology and Laboratory Medicine 6 Founders Pavilion, The Hospital for the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713447PMC
March 2009

Infliximab prevents Crohn's disease recurrence after ileal resection.

Gastroenterology 2009 Feb 31;136(2):441-50.e1; quiz 716. Epub 2008 Oct 31.

Inflammatory Bowel Disease Center and Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1053/j.gastro.2008.10.051DOI Listing
February 2009

Practical approach to the pathologic diagnosis of gastritis.

Arch Pathol Lab Med 2008 Oct;132(10):1586-93

Department of Pathology and Laboratory Medicine, Hospitalof the University of Pennsylvania, Philadelphia 19104, USA.

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http://dx.doi.org/10.1043/1543-2165(2008)132[1586:PATTPD]2.0.CO;2DOI Listing
October 2008

Polymeric immunoglobulin receptor-negative tumors represent a more aggressive type of adenocarcinomas of distal esophagus and gastroesophageal junction.

Arch Pathol Lab Med 2008 Aug;132(8):1295-301

Department of Pathology, McGill University, Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1043/1543-2165(2008)132[1295:PIRTRA]2.0.CO;2DOI Listing
August 2008

Helicobacter pylori may play a contributory role in the pathogenesis of primary sclerosing cholangitis.

Dig Dis Sci 2007 Sep 28;52(9):2265-70. Epub 2007 Mar 28.

Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1007/s10620-007-9803-7DOI Listing
September 2007

Cutting edge: transgenic expression of human MUC1 in IL-10-/- mice accelerates inflammatory bowel disease and progression to colon cancer.

J Immunol 2007 Jul;179(2):735-9

Department of Immunology, University of Pittsburgh School of Medicine, PA 15261, USA.

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http://dx.doi.org/10.4049/jimmunol.179.2.735DOI Listing
July 2007

HER-2/neu overexpression is an independent prognostic factor in colorectal cancer.

Int J Colorectal Dis 2007 May 1;22(5):491-7. Epub 2006 Sep 1.

Department of Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea.

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http://dx.doi.org/10.1007/s00384-006-0192-8DOI Listing
May 2007

Cryoglobulinemia related to hepatitis C virus infection.

Dig Dis Sci 2007 Apr 16;52(4):897-907. Epub 2007 Feb 16.

Istituto di Clinica Medica, University of Sassari, Sassari, Italy.

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http://dx.doi.org/10.1007/s10620-006-9510-9DOI Listing
April 2007

Why do African Americans get more colon cancer than Native Africans?

J Nutr 2007 01;137(1 Suppl):175S-182S

Division of Gastroenterology and Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1093/jn/137.1.175SDOI Listing
January 2007

Demonstration and characterization of mutations induced by Helicobacter pylori organisms in gastric epithelial cells.

Helicobacter 2006 Aug;11(4):272-86

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1111/j.1523-5378.2006.00408.xDOI Listing
August 2006

Assessment of microsatellite instability in very small microdissected samples and in tumor samples that are contaminated with normal DNA.

Diagn Mol Pathol 2006 Jun;15(2):63-9

Department of Pathology, University of Pittsburgh, USA.

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June 2006

Helicobacter heilmannii gastritis: a case study with review of literature.

Am J Surg Pathol 2005 Nov;29(11):1537-9

Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1097/01.pas.0000169499.96658.6eDOI Listing
November 2005

Molecular and genetic aspects of gastrointestinal and pancreatic disease.

Clin Lab Med 2005 Mar;25(1):xi-xii

Division of Gastroenterology, Hepatology and Nutrition, Director, Center for Genomic Sciences, University of Pittsburgh, UPMC Presbyterian, M2 C Wing, 200 Lothrop Street, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1016/j.cll.2005.01.001DOI Listing
March 2005

Microsatellite instability and DNA mismatch repair deficiency testing in hereditary and sporadic gastrointestinal cancers.

Clin Lab Med 2005 Mar;25(1):179-96

Department of Pathology, University of Pittsburgh, PUH-A610, 100 Lothrop Street, Pittsburgh, PA 15213-2582, USA.

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http://dx.doi.org/10.1016/j.cll.2004.12.001DOI Listing
March 2005

Molecular markers in Helicobacter pylori-associated gastric carcinogenesis.

Clin Lab Med 2005 Mar;25(1):197-222

Department of Pathology, University of Pittsburgh Medical Center, PUH-A610, 200 Lothrop Street, Pittsburgh, PA 15213-2582, USA.

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http://dx.doi.org/10.1016/j.cll.2004.12.002DOI Listing
March 2005

Alterations of DNA mismatch repair proteins and microsatellite instability levels in gastric cancer cell lines.

Lab Invest 2004 Jul;84(7):915-22

Department of Pathology, University of Pittsburgh Medical Center, 200 Lothrop Street, PUH-A610, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1038/labinvest.3700117DOI Listing
July 2004

Effects of Helicobacter pylori infection on the link between regenerating gene expression and serum gastrin levels in Mongolian gerbils.

Lab Invest 2003 Dec;83(12):1777-86

Department of Pathology, Medicine, Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas, USA.

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December 2003

Cyclooxygenase expression during Helicobacter pylori infection in Mongolian gerbils.

Dig Dis Sci 2003 Nov;48(11):2139-46

Department of Medicine, Veterans Affairs Medical Center, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1023/b:ddas.0000004517.83166.26DOI Listing
November 2003

Celecoxib and rofecoxib potentiate chronic colitis and premalignant changes in interleukin 10 knockout mice.

Inflamm Bowel Dis 2003 Jul;9(4):230-6

Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center and Pittsburgh Veterans Administration Medical Center, Pittsburgh, Pennsylvania 15213, U.S.A.

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http://pdfs.journals.lww.com/ibdjournal/2003/07000/Celecoxib
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http://dx.doi.org/10.1097/00054725-200307000-00003DOI Listing
July 2003

Helicobacter pylori and gastric malignancies.

Helicobacter 2002 ;7 Suppl 1:37-42

University of Pittsburgh Medical Center, Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA.

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November 2002

Helicobacter pylori impairs DNA mismatch repair in gastric epithelial cells.

Gastroenterology 2002 Aug;123(2):542-53

Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1053/gast.2002.34751DOI Listing
August 2002

Helicobacter infection in patients with HCV-related chronic hepatitis, cirrhosis, and hepatocellular carcinoma.

Dig Dis Sci 2002 Jul;47(7):1638-43

Institute of Internal Medicine, University of Sassari, Italy.

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http://dx.doi.org/10.1023/a:1015848009444DOI Listing
July 2002

Role of Helicobacter pylori in gastric carcinogenesis.

Gastroenterol Clin North Am 2002 Jun;31(2):517-35, x

Department of Pathology, PUH-A610, University of Pittsburgh Medical Center, 200 Lothrop St., Pittsburgh, PA 15213-2582, USA.

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June 2002