Publications by authors named "Antoni Castells"

100Publications

Moderate Inter-Observer Agreement Among Pathologists in Differentiation of Sessile Serrated From Hyperplastic Polyps.

Gastroenterology 2020 Sep 17. Epub 2020 Sep 17.

Gastroenterology and Hepatology, Veterans Affairs Medical Center, Kansas City, MO, United States; Gastroenterology, University of Kansas School of Medicine, Kansas City, KS, United States. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2020.09.015DOI Listing
September 2020

Eflornithine plus Sulindac for Prevention of Progression in Familial Adenomatous Polyposis.

N Engl J Med 2020 09;383(11):1028-1039

From the Department of Gastroenterology, Hepatology, and Nutrition, Cleveland Clinic, Cleveland (C.A.B., J.C.); the Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam (E.D., F.G.K., V.H.R.); the Department of Gastroenterology, Hepatology, and Nutrition, University of Texas M.D. Anderson Cancer Center, Houston (P.L.); the Division of Gastroenterology and Hepatology, Mayo Clinic, Phoenix (N.J.S.), and Cancer Prevention Pharmaceuticals, Tucson (A. Cohen) - both in Arizona; the Department of Gastroenterology, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, University of Barcelona, Barcelona (F.B., A. Castells); the Department of Internal Medicine I, University of Bonn (R.H., C.P.S.), and the National Center for Hereditary Tumor Syndromes (R.H., C.P.S.), Bonn, Germany; Northern Genetics Service, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne (J.B., A.H.), and Manchester Centre for Genomic Medicine, Saint Mary's Hospital, Manchester (F.L.) - both in the United Kingdom; Mount Sinai Hospital, Toronto (S. Gallinger, R.G.); the Division of Population Sciences, Dana-Farber Cancer Institute, the Division of Gastroenterology, Hepatology, and Endoscopy, Brigham and Women's Hospital, and Harvard Medical School - all in Boston (R.L., S.S.); the Division of Gastroenterology, University of Michigan, Ann Arbor (E.M.S.); Veterans Affairs San Diego Healthcare System, San Diego, and the Division of Gastroenterology, University of California San Diego, La Jolla (S. Gupta); Huntsman Cancer Center, Salt Lake City (P.K.); the University of Pennsylvania, Philadelphia (G.G.G., A.K.R.); Mayo Clinic, Rochester, MN (F.A.S.); University Hospital Gasthuisberg, Leuven, Belgium (E.V.C.); Emory University School of Medicine, Atlanta (F.F.W.); Washington University School of Medicine, St. Louis (P.E.W.); University of Washington Medical Center, Seattle (W.M.G.); Vanderbilt University Medical Center, Nashville (M.F.); and the University of Wisconsin School of Medicine and Public Health, Madison (J.M.W.).

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http://dx.doi.org/10.1056/NEJMoa1916063DOI Listing
September 2020

Genetic Counseling for Hereditary Gastric and Pancreatic Cancer in High-Risk Gastrointestinal Cancer Clinics: An Effective Strategy.

Cancers (Basel) 2020 Aug 23;12(9). Epub 2020 Aug 23.

Gastroenterology Department, Hospital Clínic de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomediques August Pi i Sunyer, 08036 Barcelona, Spain.

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http://dx.doi.org/10.3390/cancers12092386DOI Listing
August 2020

Germline biallelic Mcm8 variants are associated with early-onset Lynch-like syndrome.

JCI Insight 2020 Sep 17;5(18). Epub 2020 Sep 17.

Gastroenterology Department, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1172/jci.insight.140698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526538PMC
September 2020

Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk.

Authors:
Minta Thomas Lori C Sakoda Michael Hoffmeister Elisabeth A Rosenthal Jeffrey K Lee Franzel J B van Duijnhoven Elizabeth A Platz Anna H Wu Christopher H Dampier Albert de la Chapelle Alicja Wolk Amit D Joshi Andrea Burnett-Hartman Andrea Gsur Annika Lindblom Antoni Castells Aung Ko Win Bahram Namjou Bethany Van Guelpen Catherine M Tangen Qianchuan He Christopher I Li Clemens Schafmayer Corinne E Joshu Cornelia M Ulrich D Timothy Bishop Daniel D Buchanan Daniel Schaid David A Drew David C Muller David Duggan David R Crosslin Demetrius Albanes Edward L Giovannucci Eric Larson Flora Qu Frank Mentch Graham G Giles Hakon Hakonarson Heather Hampel Ian B Stanaway Jane C Figueiredo Jeroen R Huyghe Jessica Minnier Jenny Chang-Claude Jochen Hampe John B Harley Kala Visvanathan Keith R Curtis Kenneth Offit Li Li Loic Le Marchand Ludmila Vodickova Marc J Gunter Mark A Jenkins Martha L Slattery Mathieu Lemire Michael O Woods Mingyang Song Neil Murphy Noralane M Lindor Ozan Dikilitas Paul D P Pharoah Peter T Campbell Polly A Newcomb Roger L Milne Robert J MacInnis Sergi Castellví-Bel Shuji Ogino Sonja I Berndt Stéphane Bézieau Stephen N Thibodeau Steven J Gallinger Syed H Zaidi Tabitha A Harrison Temitope O Keku Thomas J Hudson Veronika Vymetalkova Victor Moreno Vicente Martín Volker Arndt Wei-Qi Wei Wendy Chung Yu-Ru Su Richard B Hayes Emily White Pavel Vodicka Graham Casey Stephen B Gruber Robert E Schoen Andrew T Chan John D Potter Hermann Brenner Gail P Jarvik Douglas A Corley Ulrike Peters Li Hsu

Am J Hum Genet 2020 09 5;107(3):432-444. Epub 2020 Aug 5.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2020.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477007PMC
September 2020

Centrosome reduction in newly-generated tetraploid cancer cells obtained by separase depletion.

Sci Rep 2020 06 4;10(1):9152. Epub 2020 Jun 4.

Gastrointestinal and Pancreatic Oncology Team, Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, 08036, Spain.

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http://dx.doi.org/10.1038/s41598-020-65975-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272426PMC
June 2020

COVID-19: a pandemic of values.

Authors:
Antoni Castells

Gastroenterol Hepatol 2020 Jun - Jul;43(6):329-330. Epub 2020 May 1.

Servicio de Gastroenterología, Hospital Clínic de Barcelona, IDIBAPS, CIBERehd, Universitat de Barcelona, Barcelona, España. Electronic address:

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http://dx.doi.org/10.1016/j.gastrohep.2020.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252003PMC
June 2020

MiR-93 is related to poor prognosis in pancreatic cancer and promotes tumor progression by targeting microtubule dynamics.

Oncogenesis 2020 May 4;9(5):43. Epub 2020 May 4.

Gastrointestinal & Pancreatic Oncology Group, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd)/ Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1038/s41389-020-0227-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198506PMC
May 2020

Tetraploidy-Associated Genetic Heterogeneity Confers Chemo-Radiotherapy Resistance to Colorectal Cancer Cells.

Cancers (Basel) 2020 Apr 30;12(5). Epub 2020 Apr 30.

Gastrointestinal and Pancreatic Oncology Team, Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), 08036 Barcelona, Spain.

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http://dx.doi.org/10.3390/cancers12051118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281619PMC
April 2020

Germline Mutations in FAF1 Are Associated With Hereditary Colorectal Cancer.

Gastroenterology 2020 Jul 14;159(1):227-240.e7. Epub 2020 Mar 14.

Gastroenterology Department, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Hospital Clínic, Universitat de Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2020.03.015DOI Listing
July 2020

Colorectal cancer genetic variants are also associated with serrated polyposis syndrome susceptibility.

J Med Genet 2020 Oct 13;57(10):677-682. Epub 2020 Mar 13.

Gastroenterology Department, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Hospital Clínic, Barcelona, Spain

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http://dx.doi.org/10.1136/jmedgenet-2019-106374DOI Listing
October 2020

Fecal MicroRNA-Based Algorithm Increases Effectiveness of Fecal Immunochemical Test-Based Screening for Colorectal Cancer.

Clin Gastroenterol Hepatol 2020 Feb 28. Epub 2020 Feb 28.

Gastroenterology Department, Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2020.02.043DOI Listing
February 2020

CNApp, a tool for the quantification of copy number alterations and integrative analysis revealing clinical implications.

Elife 2020 Jan 15;9. Epub 2020 Jan 15.

Gastrointestinal and Pancreatic Oncology Team, Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.7554/eLife.50267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010409PMC
January 2020

Validation of miR-1228-3p as Housekeeping for MicroRNA Analysis in Liquid Biopsies from Colorectal Cancer Patients.

Biomolecules 2019 12 20;10(1). Epub 2019 Dec 20.

Gastrointestinal & Pancreatic Oncology Group, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD) /Hospital Clínic of Barcelona/Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08036 Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.3390/biom10010016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022916PMC
December 2019

Identification and Validation of MicroRNA Profiles in Fecal Samples for Detection of Colorectal Cancer.

Gastroenterology 2020 03 14;158(4):947-957.e4. Epub 2019 Oct 14.

Gastroenterology Department, Hospital Clinic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.10.005DOI Listing
March 2020

Analysis of A 6-Mirna Signature in Serum from Colorectal Cancer Screening Participants as Non-Invasive Biomarkers for Advanced Adenoma and Colorectal Cancer Detection.

Cancers (Basel) 2019 Oct 12;11(10). Epub 2019 Oct 12.

Gastrointestinal and Pancreatic Oncology Research Group, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD)/Hospital Clínic of Barcelona/Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08036 Barcelona, Spain.

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http://dx.doi.org/10.3390/cancers11101542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827108PMC
October 2019

Using linkage studies combined with whole-exome sequencing to identify novel candidate genes for familial colorectal cancer.

Int J Cancer 2020 03 6;146(6):1568-1577. Epub 2019 Nov 6.

Gastroenterology Department, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Hospital Clínic, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/ijc.32683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004061PMC
March 2020

Principles and duties in the exercise of the medical direction of hospitals and health centers.

Med Clin (Barc) 2019 12 4;153(12):467-469. Epub 2019 Aug 4.

Colegio de Médicos de Barcelona, Barcelona, España.

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http://dx.doi.org/10.1016/j.medcli.2019.05.007DOI Listing
December 2019

Circulating biomarkers for early detection and clinical management of colorectal cancer.

Mol Aspects Med 2019 10 14;69:107-122. Epub 2019 Jun 14.

Gastrointestinal & Pancreatic Oncology Group, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD) / Hospital Clínic of Barcelona/ Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2019.06.002DOI Listing
October 2019

Novel Circulating miRNA Signatures for Early Detection of Pancreatic Neoplasia.

Clin Transl Gastroenterol 2019 04;10(4):e00029

Gastrointestinal & Pancreatic Oncology Group, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD)/Hospital Clínic of Barcelona/Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Catalonia, Spain.

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http://Insights.ovid.com/crossref?an=01720094-201904000-0000
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http://dx.doi.org/10.14309/ctg.0000000000000029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602779PMC
April 2019

Lynch-like syndrome is as frequent as Lynch syndrome in early-onset nonfamilial nonpolyposis colorectal cancer.

Int J Cancer 2019 08 23;145(3):705-713. Epub 2019 Feb 23.

Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d' Investigacions Biomediques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/ijc.32160DOI Listing
August 2019

Quantitative analysis of somatically acquired and constitutive uniparental disomy in gastrointestinal cancers.

Int J Cancer 2019 02 3;144(3):513-524. Epub 2018 Dec 3.

Gastrointestinal and Pancreatic Oncology Group, Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Catalonia, Spain.

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http://doi.wiley.com/10.1002/ijc.31936
Publisher Site
http://dx.doi.org/10.1002/ijc.31936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635747PMC
February 2019

Colorectal cancer after negative colonoscopy in fecal immunochemical test-positive participants from a colorectal cancer screening program.

Endosc Int Open 2018 Sep 11;6(9):E1140-E1148. Epub 2018 Sep 11.

Gastroenterology Department, Hospital Clinic of Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Universitat de Barcelona, Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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http://dx.doi.org/10.1055/a-0650-4296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133669PMC
September 2018

Methylation and Expression Status Does Not Predict Response to 5-FU-based Chemotherapy in Colorectal Cancer.

Clin Cancer Res 2018 06 13;24(12):2820-2827. Epub 2018 Mar 13.

Center for Gastrointestinal Research; Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A Sammons Cancer Center, Baylor Research Institute and Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-2940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396148PMC
June 2018

Zeb1 in Stromal Myofibroblasts Promotes -Driven Development of Pancreatic Cancer.

Cancer Res 2018 05 28;78(10):2624-2637. Epub 2018 Feb 28.

Gastrointestinal and pancreatic oncology research group, Hospital Clinic, Barcelona, CiberEHD, Spain.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-1882DOI Listing
May 2018

Deciphering microRNA targets in pancreatic cancer using miRComb R package.

Oncotarget 2018 Jan 8;9(5):6499-6517. Epub 2018 Jan 8.

Gastrointestinal & Pancreatic Oncology Group, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.18632/oncotarget.24034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814228PMC
January 2018

Near-tetraploid cancer cells show chromosome instability triggered by replication stress and exhibit enhanced invasiveness.

FASEB J 2018 07 8;32(7):3502-3517. Epub 2018 Feb 8.

Gastrointestinal and Pancreatic Oncology Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Hospital Clínic de Barcelona, Barcelona, Spain.

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https://www.fasebj.org/doi/10.1096/fj.201700247RR
Publisher Site
http://dx.doi.org/10.1096/fj.201700247RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998968PMC
July 2018

An evaluation of the SENTiFIT 270 analyser for quantitation of faecal haemoglobin in the investigation of patients with suspected colorectal cancer.

Clin Chem Lab Med 2018 03;56(4):625-633

Gastroenterology Department, Hospital Clinic, University of Barcelona, Barcelona, Spain; and IDIBAPS, CIBERehd, Barcelona, Spain.

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http://dx.doi.org/10.1515/cclm-2017-0605DOI Listing
March 2018

Increased IFRD1 Expression in Human Colon Cancers Predicts Reduced Patient Survival.

Dig Dis Sci 2017 12 1;62(12):3460-3467. Epub 2017 Nov 1.

Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, Box 8124, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1007/s10620-017-4819-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167971PMC
December 2017

Impact of comorbid conditions on participation in an organised colorectal cancer screening programme: a cross-sectional study.

BMC Cancer 2017 Aug 7;17(1):524. Epub 2017 Aug 7.

Unitat de Suport a la Recerca Metropolitana Sud, Institut Universitari d'Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), Cornellà de Llobregat, Spain.

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http://dx.doi.org/10.1186/s12885-017-3516-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547546PMC
August 2017

Post-colonoscopy colorectal cancer: Next enemy to beat.

Authors:
Antoni Castells

Med Clin (Barc) 2018 01 13;150(1):24-25. Epub 2017 Jul 13.

Servei de Gastroenterologia, Hospital Clínic, Universitat de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, España. Electronic address:

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http://dx.doi.org/10.1016/j.medcli.2017.06.002DOI Listing
January 2018

POLE and POLD1 screening in 155 patients with multiple polyps and early-onset colorectal cancer.

Oncotarget 2017 Apr;8(16):26732-26743

Gastroenterology Department, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), University of Barcelona, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.18632/oncotarget.15810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432293PMC
April 2017

Increased Risk of Colorectal Cancer in Patients With Multiple Serrated Polyps and Their First-Degree Relatives.

Gastroenterology 2017 07 9;153(1):106-112.e2. Epub 2017 Apr 9.

Research Laboratory, Alicante University General Hospital, Alicante Institute for Health and Biomedical Research Instituto de Investigación Sanitaria y Biomédica de Alicante, Alicante, Spain; Service of Digestive Medicine, Alicante University General Hospital, Alicante Institute for Health and Biomedical Research Instituto de Investigación Sanitaria y Biomédica de Alicante, Alicante, Spain. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.04.003DOI Listing
July 2017

Transcription-dependent radial distribution of TCF7L2 regulated genes in chromosome territories.

Chromosoma 2017 Oct 25;126(5):655-667. Epub 2017 Mar 25.

Unitat de Biologia Cel·lular i Genètica Mèdica, Departament de Biologia Cel·lular, Fisiologia i Immunologia, Facultat de Medicina, Universitat Autònoma de Barcelona, 08193, Bellaterra, Catalonia, Spain.

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http://dx.doi.org/10.1007/s00412-017-0629-6DOI Listing
October 2017

Lymph node pooling: a feasible and efficient method of lymph node molecular staging in colorectal carcinoma.

J Transl Med 2017 01 14;15(1):14. Epub 2017 Jan 14.

Pathology Department-Centre de Diagnòstic Biomèdic (CDB), Hospital Clínic, University of Barcelona, Escala 3, Planta 5, 08036, Barcelona, Spain.

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http://dx.doi.org/10.1186/s12967-016-1114-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237515PMC
January 2017

Surveillance of patients with hereditary gastrointestinal cancer syndromes.

Best Pract Res Clin Gastroenterol 2016 Dec 21;30(6):923-935. Epub 2016 Oct 21.

Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), IDIBAPS, University of Barcelona, Villarroel 170, 08036 Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bpg.2016.10.004DOI Listing
December 2016

Relationship Between Enterococcus faecalis Infective Endocarditis and Colorectal Neoplasm: Preliminary Results From a Cohort of 154 Patients.

Rev Esp Cardiol (Engl Ed) 2017 Jun 9;70(6):451-458. Epub 2017 Mar 9.

Servicio de Enfermedades Infecciosas, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.rec.2016.10.013DOI Listing
June 2017

Hereditary forms of colorectal cancer.

Authors:
Antoni Castells

Gastroenterol Hepatol 2016 Sep;39 Suppl 1:62-67

Servicio de Gastroenterología, Hospital Clínic, Universitat de Barcelona, IDIBAPS, CIBERehd, Barcelona, España. Electronic address:

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http://dx.doi.org/10.1016/S0210-5705(16)30176-5DOI Listing
September 2016

America, We Are Confused: The Updated U.S. Preventive Services Task Force Recommendation on Colorectal Cancer Screening.

Ann Intern Med 2017 Jan 8;166(2):139-140. Epub 2016 Nov 8.

From University of Oslo, Oslo University Hospital, and Cancer Registry of Norway, Oslo, Norway; Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland; Nuovo Regina Margherita Hospital, Rome, Italy; Sørlandet Hospital, Kristiansand, Norway; Telemark Hospital, Skien, Norway; Hospital Clínic, Barcelona, Spain; and Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.7326/M16-1805DOI Listing
January 2017

Reassessment colonoscopy to diagnose serrated polyposis syndrome in a colorectal cancer screening population.

Endoscopy 2017 Jan 14;49(1):44-53. Epub 2016 Oct 14.

Department of Gastroenterology, Hospital Clínic de Barcelona; and Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1055/s-0042-115640DOI Listing
January 2017

Major milestones in translational oncology.

BMC Med 2016 07 28;14(1):110. Epub 2016 Jul 28.

Department of Urology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12916-016-0654-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964079PMC
July 2016

Endoscopic tattooing of early colon carcinoma enhances detection of lymph nodes most prone to harbor tumor burden.

Surg Endosc 2017 02 20;31(2):723-733. Epub 2016 Jun 20.

Pathology Department-Centre de Diagnostic Biomedic (CDB), Hospital Clínic, University of Barcelona (CIBERehd) and Banc de Tumors-Biobanc Clinic-IDIBAPS-XBTC, Escala 3, Planta 5, Villarroel 170, 08036, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00464-016-5026-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266760PMC
February 2017

Analysis of participant satisfaction in the Barcelona colorectal cancer screening programme: Positive evaluation of the community pharmacy.

Gastroenterol Hepatol 2017 Apr 10;40(4):265-275. Epub 2016 Jun 10.

Servicio de Epidemiología y Evaluación, Hospital del Mar, Barcelona, España; Instituto Hospital del Mar de Investigaciones Médicas (IMIM), Barcelona, España; Red de investigación en servicios de salud en enfermedades crónicas (REDISSEC), España.

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http://dx.doi.org/10.1016/j.gastrohep.2016.04.015DOI Listing
April 2017

MicroRNAs for Detection of Pancreatic Neoplasia: Biomarker Discovery by Next-generation Sequencing and Validation in 2 Independent Cohorts.

Ann Surg 2017 06;265(6):1226-1234

*Gastrointestinal & Pancreatic Oncology Group, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD)/Hospital Clínic of Barcelona/ Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Catalonia, Spain †Bioinformatics Platform, CIBEREHD/Barcelona, Catalonia, Spain ‡Pathology Department, Hospital Clínic of Barcelona, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1097/SLA.0000000000001809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434964PMC
June 2017

The Fanconi anemia DNA damage repair pathway in the spotlight for germline predisposition to colorectal cancer.

Eur J Hum Genet 2016 10 11;24(10):1501-5. Epub 2016 May 11.

Gastroenterology Department, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1038/ejhg.2016.44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027689PMC
October 2016

Twelve-year asymptomatic retention of a colon capsule endoscope.

Gastrointest Endosc 2017 Mar 6;85(3):681-682. Epub 2016 May 6.

Endoscopy Unit, Gastroenterology Department, Radiology Department, Hospital Clinic, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.gie.2016.04.045DOI Listing
March 2017

Genetic Variants Associated with Colorectal Adenoma Susceptibility.

PLoS One 2016 14;11(4):e0153084. Epub 2016 Apr 14.

Department of Gastroenterology, Hospital del Mar, IMIM (Hospital del Mar Medical Research Institute), Pompeu Fabra University, Passeig Marítim 25-29, 08003, Barcelona, Catalonia, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0153084PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831735PMC
August 2016

Impact of age- and gender-specific cut-off values for the fecal immunochemical test for hemoglobin in colorectal cancer screening.

Dig Liver Dis 2016 May 9;48(5):542-551. Epub 2016 Feb 9.

Department of Gastroenterology, Hospital del Mar, Cancer Research Program, IMIM (Hospital del Mar Medical Research Institute), Autonomous University of Barcelona and Pompeu Fabra University, Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2016.02.001DOI Listing
May 2016

[Hereditary gastric and pancreatic cancer predisposition syndromes].

Gastroenterol Hepatol 2016 Aug-Sep;39(7):481-93. Epub 2016 Feb 23.

Servicio de Gastroenterología, Hospital Clínic de Barcelona, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, España. Electronic address:

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http://dx.doi.org/10.1016/j.gastrohep.2015.11.009DOI Listing
December 2017

Endoscopist characteristics that influence the quality of colonoscopy.

Endoscopy 2016 Mar 4;48(3):241-7. Epub 2016 Feb 4.

Department of Gastroenterology, Hospital Universitario de Canarias, Instituto Universitario de Tecnologías Biomédicas (ITB) & Centro de Investigación Biomédica de Canarias (CIBICAN), Departamento de Medicina Interna, Universidad de La Laguna, Santa Cruz de Tenerife, Spain.

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http://dx.doi.org/10.1055/s-0042-100185DOI Listing
March 2016

Modeling Respiratory Depression Induced by Remifentanil and Propofol during Sedation and Analgesia Using a Continuous Noninvasive Measurement of pCO2.

J Pharmacol Exp Ther 2016 Mar 11;356(3):563-73. Epub 2015 Dec 11.

Pharmacometrics and Systems Pharmacology, Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy, University of Navarra, Pamplona, Spain (J.A.H., I.F.T.); Department of Anaesthesiology, School of Medicine, University of Auckland, Auckland, New Zealand (J.A.H.); Systems Pharmacology Effect Control and Modeling Research Group, Department of Anesthesia, Hospital CLINIC de Barcelona, Barcelona, Spain (X.B., J.F.V., A.P., P.L.G.); Electronic Engineering Program, School of Engineering. Universidad de San Buenaventura, Cali, Colombia (J.F.V.); Centre for Biomedical Engineering Research, Universitat Politècnica de Catalunya, Barcelona, Spain (E.W.J.); Gastroenterology Department, Hospital CLINIC, CIBERehd, Institut d'investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain (J.M., S.C.-B., A.C.); Department of Anesthesia and Perioperative Care, University of California, San Francisco, California (P.L.G.); and Neuroimmunology Research Group, Institut d'investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain (P.L.G.)

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http://jpet.aspetjournals.org/content/early/2015/12/11/jpet.
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http://jpet.aspetjournals.org/cgi/doi/10.1124/jpet.115.22697
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http://dx.doi.org/10.1124/jpet.115.226977DOI Listing
March 2016

[Colorectal cancer screening].

Authors:
Antoni Castells

Gastroenterol Hepatol 2015 Sep;38 Suppl 1:64-70

Servicio de Gastroenterología, Hospital Clínic, IDIBAPS, CIBERehd, Universitat de Barcelona, Barcelona, España. Electronic address:

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http://dx.doi.org/10.1016/S0210-5705(15)30021-2DOI Listing
September 2015

Let-7 Represses Carcinogenesis and a Stem Cell Phenotype in the Intestine via Regulation of Hmga2.

PLoS Genet 2015 Aug 5;11(8):e1005408. Epub 2015 Aug 5.

Division of Gastroenterology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America; Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America; Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526516PMC
August 2015

Choosing the optimal method in programmatic colorectal cancer screening: current evidence and controversies.

Authors:
Antoni Castells

Therap Adv Gastroenterol 2015 Jul;8(4):221-33

Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), IDIBAPS, University of Barcelona, Villarroel 170, 08036-Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1177/1756283X15578610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480573PMC
July 2015