Publications

Risk of relapse after antidepressant discontinuation in anxiety disorders, obsessive-compulsive disorder, and post-traumatic stress disorder: systematic review and meta-analysis of relapse prevention trials.
BMJ 2017 Sep 13;358:j3927. Epub 2017 Sep 13.
Department of Psychiatry and Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, VU University Medical Center Amsterdam, Amsterdam, Netherlands.

Cost-effectiveness of interventions for treating anxiety disorders: A systematic review.
J Affect Disord 2017 Mar 13;210:1-13. Epub 2016 Dec 13.
Centre of Economic Evaluation, Trimbos Institute, Netherlands Institute for Mental Health and Addiction, Utrecht, The Netherlands; Department of Health Services Research, CAPHRI School of Public Health and Primary Care, Maastricht University, Maastricht, The Netherlands. Electronic address:

Prognostic association of cardiac anxiety with new cardiac events and mortality following myocardial infarction.
Br J Psychiatry 2016 Nov 18;209(5):400-406. Epub 2016 Aug 18.
Maria H. C. T. Van Beek, MD, Department of Psychiatry, Radboud University Medical Centre, Nijmegen, The Netherlands; Marij Zuidersma, PhD, University Medical Center Groningen, University Center for Psychiatry, and Interdisciplinary Center for Psychopathology and Emotion Regulation, University of Groningen, Groningen, The Netherlands; Martijn Lappenschaar, MD, PhD, Department of Psychiatry, Radboud University Medical Centre, Nijmegen, The Netherlands; Gheorghe Pop, MD, PhD, Department of Cardiology, Radboud University Medical Centre Nijmegen, Nijmegen, The Netherlands; Annelieke M. Roest, PhD, University Medical Center Groningen, University Center for Psychiatry, and Interdisciplinary Center for Psychopathology and Emotion Regulation, University of Groningen, Groningen, The Netherlands; Anton J. L. M. Van Balkom, MD, PhD, Department of Psychiatry and EMGO+ Institute, VU University Medical Center, GGZinGeest, Amsterdam, The Netherlands; Anne E. M. Speckens, MD, PhD, Department of Psychiatry, Radboud University Medical Centre, Nijmegen, The Netherlands; Richard C. Oude Voshaar, MD, PhD, University Medical Center Groningen, University Center for Psychiatry, and Interdisciplinary Center for Psychopathology and Emotion Regulation, University of Groningen, Groningen, The Netherlands.


Diagnostic instability of recurrence and the impact on recurrence rates in depressive and anxiety disorders.
J Affect Disord 2016 May 9;195:185-90. Epub 2016 Feb 9.
Department of Psychiatry, VU University Medical Center, A.J. Ernststraat 1187, 1081 HL Amsterdam, The Netherlands; EMGO Institute for Health and Care Research, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.

Anxiety and new onset of cardiovascular disease: critical review and meta-analysis.
Br J Psychiatry 2016 Mar;208(3):223-31
Neeltje M. Batelaan, MD, PhD, Adrie Seldenrijk, PhD, Mariska Bot, PhD, Anton J. L. M. van Balkom, MD, PhD, Brenda W. J. H. Penninx, PhD, Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Centre, Amsterdam, The Netherlands.

Assignment refusal and its relation to outcome in a randomized controlled trial comparing Cognitive Therapy and Fluvoxamine in treatment-resistant patients with obsessive compulsive disorder.
Psychiatry Res 2015 Mar 12;226(1):198-203. Epub 2015 Jan 12.
Department of Psychiatry and EMGO(+) Institute, VU University Medical Center, Academic Outpatient Clinic for Anxiety Disorders, GGZinGeest, Amsterdam, The Netherlands.

Compensatory frontoparietal activity during working memory: an endophenotype of obsessive-compulsive disorder.
Biol Psychiatry 2014 Dec 1;76(11):878-87. Epub 2013 Dec 1.
Department of Psychiatry (FEdV, SJdW, VvdB, TBvR, AJLMvB, DJV, OAvdH), VU University Medical Center, Amsterdam; Neuroscience Campus Amsterdam (FEdV, SJdW, YDvdW, DJV, OAvdH), VU University, Amsterdam; Department of Anatomy and Neurosciences (YDvdW, OAvdH), VU University Medical Center, Amsterdam.

Personality predicts time to remission and clinical status in hypochondriasis during a 6-year follow-up.
J Nerv Ment Dis 2014 May;202(5):402-7
*Department of Clinical, Health and Neuropsychology, Leiden University, Leiden, The Netherlands; †Department of Anxiety Disorders, PsyQ, The Hague, The Netherlands; ‡Department of Psychiatry and EMGO+ Institute, VU University Medical Center, GGZinGeest, Amsterdam, The Netherlands; and §Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands.

The effectiveness of adhering to clinical-practice guidelines for anxiety disorders in secondary mental health care: the results of a cohort study in the Netherlands.
J Eval Clin Pract 2013 Oct 15;19(5):791-7. Epub 2012 May 15.
Health-care Psychologist and PhD Student, HSK Group, Arnhem, The Netherlands Psychiatrist, Department of Psychiatry, UMC St. Radboud, Overwaal Centre for Anxiety Disorders, Nijmegen, The Netherlands Extraordinary Professor of Health-care Psychology and Clinical Psychologist, SPON Postdoctoral Education, Academic Centre Social Sciences, Behavioural Science Institute, Radboud University, Nijmegen, The Netherlands Professor of Psychiatry, Department of Psychiatry and EMGO Institute, VU University Medical Center and GGZinGeest, Amsterdam, the Netherlands.

Inverse correlation between cardiac injury and cardiac anxiety: a potential role for communication.
J Cardiovasc Nurs 2014 Sep-Oct;29(5):448-53
Maria H.C.T. van Beek, MD Psychiatrist, Radboud University Nijmegen Medical Centre, Department of Psychiatry, Nijmegen, the Netherlands. Richard C. Oude Voshaar, MD, PhD Senior researcher at the Radboud University Nijmegen Medical Centre, Department of Psychiatry, Nijmegen, and Professor, Old Age Psychiatry at University Center of Psychiatry, University Medical Center Groningen, Groningen, the Netherlands. Femke M. van Deelen, MD Medical Doctor, Radboud University Nijmegen Medical Centre, Department of Psychiatry, Nijmegen, the Netherlands. Anton J.L.M. van Balkom, MD, PhD Professor of Psychiatry, Department of Psychiatry and EMGO+ Institute, VU University Medical Centre and GGZinGeest, Amsterdam, the Netherlands. Gheorghe Pop, MD, PhD Cardiologist, Radboud University Nijmegen Medical Centre, Department of Cardiology, Nijmegen, the Netherlands. Anne E.M. Speckens, MD, PhD Professor of Psychiatry, Radboud University Nijmegen Medical Centre, Department of Psychiatry, Nijmegen, the Netherlands.



Clinical relevance of comorbidity in anxiety disorders: a report from the Netherlands Study of Depression and Anxiety (NESDA).
J Affect Disord 2012 Mar 10;137(1-3):106-12. Epub 2012 Jan 10.
Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands.

The impact of depression on the treatment of obsessive-compulsive disorder: results from a 5-year follow-up.
J Affect Disord 2011 Dec 1;135(1-3):201-7. Epub 2011 Sep 1.
Department of Psychiatry and Institute for Research in Extramural Medicine, VU-University Medical Center and Academic Outpatient Clinic for Anxiety Disorders, GGZ InGeest, Amsterdam, The Netherlands.



Comorbidity patterns of anxiety and depressive disorders in a large cohort study: the Netherlands Study of Depression and Anxiety (NESDA).
J Clin Psychiatry 2011 Mar 25;72(3):341-8. Epub 2011 Jan 25.
Department of Psychiatry/EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands.

Does the therapy manual or the therapist matter most in treatment of obsessive-compulsive disorder? A randomized controlled trial of exposure with response or ritual prevention in 118 patients.
J Clin Psychiatry 2010 Sep 23;71(9):1158-67. Epub 2010 Mar 23.
Department of Psychiatry and Institute for Research in Extramural Medicine, GGZ InGeest/VU Medical Center Academic Anxiety Outpatient Clinic, A.J. Ernststraat 887, 1081 HL Amsterdam, The Netherlands.


The role of the COMT Val(158)Met polymorphism in the phenotypic expression of obsessive-compulsive disorder.
Am J Med Genet B Neuropsychiatr Genet 2010 Jan;153B(1):167-76
Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.



Measuring obsessive-compulsive symptoms: Padua Inventory-Revised vs. Yale-Brown Obsessive Compulsive Scale.
J Anxiety Disord 2009 Aug 24;23(6):830-5. Epub 2009 Apr 24.
Department of Psychiatry, EMGO Institute University Medical Center, Academic Outpatient Clinic for Anxiety Disorders, GGZ inGeest, A.J.Ernststraat 887, Amsterdam 1081 HL, The Netherlands.

Reduced orbitofrontal-striatal activity on a reversal learning task in obsessive-compulsive disorder.
Arch Gen Psychiatry 2006 Nov;63(11):1225-36
Department of Psychiatry, VU University Medical Center, Graduate School of Neurosciences, and Outpatient Academic Clinic for Anxiety Disorders, GGZ Buitenamstel, Amsterdam, the Netherlands.



Cognitive therapy versus fluvoxamine as a second-step treatment in obsessive-compulsive disorder nonresponsive to first-step behavior therapy.
Psychother Psychosom 2012 6;81(6):366-74. Epub 2012 Sep 6.
Department of Psychiatry and EMGO Institute, VU University Medical Center, Academic Outpatient Clinic for Anxiety Disorders, GGZinGeest, Amsterdam, The Netherlands.

Treatment compliance and effectiveness in complex PTSD patients with co-morbid personality disorder undergoing stabilizing cognitive behavioral group treatment: a preliminary study.
Eur J Psychotraumatol 2013 6;4. Epub 2013 Nov 6.
GGZ inGeest, Amsterdam, The Netherlands ; Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands ; EMGO Institute, VU University Medical Center, Amsterdam, The Netherlands ; PsyQ, Parnassiagroep, The Hague, The Netherlands.

Response to "Treatment compliance and effectiveness in complex PTSD patients with co-morbid personality disorder undergoing stabilizing cognitive behavioral group treatment: a preliminary study" - authors' reply.
Eur J Psychotraumatol 2014 5;5. Epub 2014 Feb 5.
GGZ inGeest, Amsterdam, The Netherlands, Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands, EMGO Institute, VU University Medical Center, Amsterdam, The Netherlands.

Feasibility and outcome of the implementation of a screening program for panic disorder in noncardiac chest pain patients in cardiac emergency department routine care.
Gen Hosp Psychiatry 2015 Sep-Oct;37(5):485-7. Epub 2015 Jun 10.
Department of Psychiatry and the EMGO Institute for Health and Care Research, VU-University Medical Center Amsterdam and GGZ inGeest, De Boelelaan 1117, 1081 HZ Amsterdam, The Netherlands. Electronic address:

The Prognostic Effect of Physical Health Complaints With New Cardiac Events and Mortality in Patients With a Myocardial Infarction.
Psychosomatics 2017 Mar - Apr;58(2):121-131. Epub 2016 Nov 5.
University Center for Psychiatry and Interdisciplinary Center Psychopathology and Emotion Regulation, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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