Anton Berns

Anton Berns

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Tumor Heterogeneity Underlies Differential Cisplatin Sensitivity in Mouse Models of Small-Cell Lung Cancer.

Cell Rep 2019 Jun;27(11):3345-3358.e4

Oncode Institute, Division of Molecular Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands; Division of Molecular Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.05.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581744PMC
June 2019

Quality-assured research environments for translational cancer research.

Authors:
Anton Berns

Mol Oncol 2019 03 22;13(3):543-548. Epub 2019 Feb 22.

Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1002/1878-0261.12441
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http://dx.doi.org/10.1002/1878-0261.12441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396364PMC
March 2019

Boosting the social impact of innovative cancer research - towards a mission-oriented approach to cancer.

Mol Oncol 2019 03 27;13(3):497-501. Epub 2019 Feb 27.

Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/1878-0261.12464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396369PMC
March 2019

A natural WNT signaling variant potently synergizes with Cdkn2ab loss in skin carcinogenesis.

Nat Commun 2019 03 29;10(1):1425. Epub 2019 Mar 29.

Oncode Institute, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41467-019-09321-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441055PMC
March 2019

European Academy of Cancer Sciences-Designation of Comprehensive Cancer Centres of Excellence.

Eur J Cancer 2018 04 14;93:138-139. Epub 2018 Feb 14.

The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ejca.2018.01.003DOI Listing
April 2018

Rejuvenation by Therapeutic Elimination of Senescent Cells.

Cell 2017 03;169(1):3-5

Division of Molecular Genetics, the Netherlands Cancer Institute, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.03.014DOI Listing
March 2017

Awakening of "Schlafen11" to Tackle Chemotherapy Resistance in SCLC.

Cancer Cell 2017 02;31(2):169-171

The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.01.013DOI Listing
February 2017

Drugging the addict: non-oncogene addiction as a target for cancer therapy.

EMBO Rep 2016 11 4;17(11):1516-1531. Epub 2016 Oct 4.

Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands

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http://dx.doi.org/10.15252/embr.201643030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090709PMC
November 2016

SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin.

Cancer Cell 2016 10;30(4):519-532

Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands; Skolkovo Institute of Science and Technology, Skolkovo Innovation Center, Building 5, Moscow 143026, Russia. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065004PMC
October 2016

We Are Standing on the Shoulders of Giants.

Authors:
Anton Berns

Cancer Res 2016 08;76(15):4307-8

The Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1870DOI Listing
August 2016

The steady progress of targeted therapies, promising advances for lung cancer.

Ecancermedicalscience 2016 28;10:638. Epub 2016 Apr 28.

Division of Molecular Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands; Skolkovo Institute of Science and Technology, Skolkovo Innovation Centre, Building 5, Moscow 143026, Russia.

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http://dx.doi.org/10.3332/ecancer.2016.638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898931PMC
June 2016

Tumor heterogeneity-induced signaling regulates SCLC metastasis.

Cell Cycle 2015 ;14(21):3347-8

a Division of Molecular Genetics; The Netherlands Cancer Institute ; Amsterdam , The Netherlands.

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http://dx.doi.org/10.1080/15384101.2015.1093445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825558PMC
February 2016

Polycomb Repressive Complex 2 Is a Barrier to KRAS-Driven Inflammation and Epithelial-Mesenchymal Transition in Non-Small-Cell Lung Cancer.

Cancer Cell 2016 Jan;29(1):17-31

Division of Molecular Genetics, Centre for Biomedical Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands; Cancer Genomics Centre (CGC.nl), Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.12.006DOI Listing
January 2016

Using the GEMM-ESC strategy to study gene function in mouse models.

Nat Protoc 2015 Nov 15;10(11):1755-85. Epub 2015 Oct 15.

Division of Molecular Pathology and Cancer Genomics Centre Netherlands, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/nprot.2015.114DOI Listing
November 2015

Paracrine signaling between tumor subclones of mouse SCLC: a critical role of ETS transcription factor Pea3 in facilitating metastasis.

Genes Dev 2015 Aug 27;29(15):1587-92. Epub 2015 Jul 27.

Division of Molecular Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands; Skolkovo Institute of Science and Technology, Skolkovo Innovation Center, Moscow 143026, Russia.

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http://dx.doi.org/10.1101/gad.262998.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536306PMC
August 2015

Origins, genetic landscape, and emerging therapies of small cell lung cancer.

Genes Dev 2015 Jul;29(14):1447-62

Division of Molecular Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1101/gad.263145.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526731PMC
July 2015

Wnt Down, Tumors Wind Up?

Cell 2015 Jun;161(7):1494-6

Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121. 1066 CX Amsterdam, The Netherlands; Skolkovo Institute of Science and Technology, Skolkovo Innovation Center, Building 5, Moscow 143026, Russia. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.06.008DOI Listing
June 2015

The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung.

J Thorac Oncol 2015 Apr;10(4):553-64

*Hamon Center for Therapeutic Oncology Research and Department of Pathology, UT Southwestern Medical Center, Dallas, TX; †Department of Neuroscience, UT Southwestern Medical Center, Dallas, TX; ‡Cancer Genomics Centre, The Netherlands Cancer Institute, Amsterdam, The Netherlands; §Departments of Pediatrics and Genetics, Stanford University, Stanford, CA; ‖Center for Cancer Research, National Cancer Institute, Bethesda, MD; ¶Division of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA; #David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142; **Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY; and ††Departementd'Anatomie et Cytologie Pathologiques, INSERM Unit 823, Centre Hospitalier Universitaire Albert Michallon, and Institut Albert Bonniot University, Grenoble, France.

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http://dx.doi.org/10.1097/JTO.0000000000000459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523224PMC
April 2015

Using TRIP for genome-wide position effect analysis in cultured cells.

Nat Protoc 2014 8;9(6):1255-81. Epub 2014 May 8.

1] Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands. [2] Cancer Genomics Centre, The Netherlands.

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http://dx.doi.org/10.1038/nprot.2014.072DOI Listing
December 2014

Improved pregnancy and birth rates with routine application of nonsurgical embryo transfer.

Transgenic Res 2014 Aug 6;23(4):691-5. Epub 2014 May 6.

MCCA Transgenic Core Facility, The Netherlands Cancer Institute, 1066 CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s11248-014-9802-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053600PMC
August 2014

Tumor microenvironment revisited.

EMBO Rep 2014 May 14;15(5):458-9. Epub 2014 Apr 14.

Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/embr.201438794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210104PMC
May 2014

Multiple cells-of-origin of mutant K-Ras-induced mouse lung adenocarcinoma.

Proc Natl Acad Sci U S A 2014 Apr 28;111(13):4952-7. Epub 2014 Feb 28.

Division of Molecular Genetics, Centre for Biomedical Genetics, and Department of Experimental Animal Pathology, The Netherlands Cancer Institute, 1066 CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1073/pnas.1319963111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977239PMC
April 2014

Chromatin position effects assayed by thousands of reporters integrated in parallel.

Cell 2013 Aug;154(4):914-27

Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.cell.2013.07.018DOI Listing
August 2013

Break the loop, escape the cycle?

EMBO J 2013 Jul 7;32(14):1967-9. Epub 2013 Jun 7.

Division of Molecular Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/emboj.2013.137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715859PMC
July 2013

Mouse models for lung cancer.

Mol Oncol 2013 Apr 19;7(2):165-77. Epub 2013 Feb 19.

Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.molonc.2013.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528410PMC
April 2013

Mouse models of cancer.

Mol Oncol 2013 Apr 26;7(2):143-5. Epub 2013 Feb 26.

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http://dx.doi.org/10.1016/j.molonc.2013.02.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528419PMC
April 2013

Frat2 mediates the oncogenic activation of Rac by MLL fusions.

Blood 2012 Dec 16;120(24):4819-28. Epub 2012 Oct 16.

Molecular Haematology and Cancer Biology Unit, UCL Institute of Child Health, London, United Kingdom.

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http://dx.doi.org/10.1182/blood-2012-05-432534DOI Listing
December 2012

Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours.

Nature 2012 Feb 22;482(7386):538-41. Epub 2012 Feb 22.

Division of Molecular Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/nature10790DOI Listing
February 2012

Rapid validation of cancer genes in chimeras derived from established genetically engineered mouse models.

Bioessays 2011 Sep 7;33(9):701-10. Epub 2011 Jul 7.

Division of Molecular Genetics, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/bies.201100018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179600PMC
September 2011

Computational identification of insertional mutagenesis targets for cancer gene discovery.

Nucleic Acids Res 2011 Aug 7;39(15):e105. Epub 2011 Jun 7.

Bioinformatics and Statistics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/nar/gkr447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159484PMC
August 2011

Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung.

Cancer Cell 2011 Jun;19(6):754-64

Division of Molecular Genetics, Centre for Biomedical Genetics, Cancer Genomics Centre, The Netherlands Cancer Institute, Amsterdam.

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http://dx.doi.org/10.1016/j.ccr.2011.04.019DOI Listing
June 2011

A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer.

Cancer Cell 2011 Feb;19(2):244-56

Division of Molecular Genetics and Center of Biomedical Genetics, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ccr.2010.12.021DOI Listing
February 2011

For better or for worse: the role of Pim oncogenes in tumorigenesis.

Nat Rev Cancer 2011 Jan 9;11(1):23-34. Epub 2010 Dec 9.

Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, The Netherlands.

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http://www.nature.com/articles/nrc2986
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http://dx.doi.org/10.1038/nrc2986DOI Listing
January 2011

Cancer: The blind spot of p53.

Authors:
Anton Berns

Nature 2010 Nov;468(7323):519-20

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http://dx.doi.org/10.1038/468519aDOI Listing
November 2010

Cell of origin of lung cancer.

Mol Oncol 2010 Oct 8;4(5):397-403. Epub 2010 Jun 8.

Division of Molecular Genetics and Centre for Biomedical Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.molonc.2010.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527931PMC
October 2010

Rapid and robust transgenic high-grade glioma mouse models for therapy intervention studies.

Clin Cancer Res 2010 Jul 14;16(13):3431-41. Epub 2010 May 14.

Department of Clinical Chemistry/Preclinical Pharmacology, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-3414DOI Listing
July 2010

Drugging drug resistance.

Cell 2010 Apr;141(1):18-20

Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S009286741000293
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http://dx.doi.org/10.1016/j.cell.2010.03.020DOI Listing
April 2010

Immune response in lung cancer mouse model mimics human anti-Hu reactivity.

J Neuroimmunol 2009 Dec 17;217(1-2):38-45. Epub 2009 Sep 17.

Departments of Surgery and of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California/Norris Cancer Center, 1441 Eastlake Ave. NOR 6420, Norris Cancer Center, Los Angeles, CA 90089, United States.

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http://dx.doi.org/10.1016/j.jneuroim.2009.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788043PMC
December 2009

High-throughput insertional mutagenesis screens in mice to identify oncogenic networks.

Nat Rev Cancer 2009 Jun;9(6):389-99

Division of Molecular Genetics, The Cancer Genomics Centre, The Centre of Biomedical Genetics, Academic Medical Center, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, The Netherlands.

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http://www.nature.com/articles/nrc2647
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http://dx.doi.org/10.1038/nrc2647DOI Listing
June 2009

Jump-starting cancer gene discovery.

Nat Biotechnol 2009 Mar;27(3):251-2

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http://dx.doi.org/10.1038/nbt0309-251DOI Listing
March 2009

Kras and Hras--what is the difference?

Authors:
Anton Berns

Nat Genet 2008 Oct;40(10):1149-50

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http://dx.doi.org/10.1038/ng1008-1149DOI Listing
October 2008

A tRNA with oncogenic capacity.

Authors:
Anton Berns

Cell 2008 Apr;133(1):29-30

Division of Molecular Genetics, Cancer Genomics Centre, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.cell.2008.03.017DOI Listing
April 2008

A conditional mouse model for malignant mesothelioma.

Cancer Cell 2008 Mar;13(3):261-71

Department of Molecular Genetics, Cancer Genomics Centre, Centre for Biomedical Genetics, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ccr.2008.01.030DOI Listing
March 2008

Targeted anticancer therapies: mouse models help uncover the mechanisms of tumor escape.

Cancer Cell 2008 Jan;13(1):5-7

Division of Molecular Genetics and Centre of Biomedical Genetics, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ccr.2007.12.019DOI Listing
January 2008

Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence.

Cancer Res 2007 Aug;67(15):7525-33

Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-0668DOI Listing
August 2007

p15Ink4b is a critical tumour suppressor in the absence of p16Ink4a.

Nature 2007 Aug;448(7156):943-6

Division of Molecular Genetics and Centre for Biomedical Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/nature06084DOI Listing
August 2007

Knockout mouse models to study Wnt signal transduction.

Trends Genet 2006 Dec 11;22(12):678-89. Epub 2006 Oct 11.

Netherlands Cancer Institute, Division of Molecular Genetics and Center for Biomedical Genetics, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S016895250600338
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http://dx.doi.org/10.1016/j.tig.2006.10.001DOI Listing
December 2006

Cancer biology: can less be more for p53?

Authors:
Anton Berns

Nature 2006 Sep;443(7108):153-4

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http://www.nature.com/doifinder/10.1038/443153a
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http://dx.doi.org/10.1038/443153aDOI Listing
September 2006

TXR1-mediated thrombospondin repression: a novel mechanism of resistance to taxanes?

Genes Dev 2006 Aug;20(15):1975-81

Netherlands Cancer Institute, Division of Molecular Genetics and Centre of Biomedical Genetics, Amsterdam.

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http://dx.doi.org/10.1101/gad.1460806DOI Listing
August 2006

Cross-species oncogenomics in cancer gene identification.

Cell 2006 Jun;125(7):1230-3

Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.cell.2006.06.018DOI Listing
June 2006

An inducible mouse model of melanoma expressing a defined tumor antigen.

Cancer Res 2006 Mar;66(6):3278-86

Ludwig Institute for Cancer Research and Cellular Genetics Unit, Université Catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-3216DOI Listing
March 2006

Re-evaluating the role of Frat in Wnt-signal transduction.

Cell Cycle 2005 Aug 1;4(8):1065-72. Epub 2005 Aug 1.

Netherlands Cancer Institute, Division of Molecular Genetics and Centre of Biomedical Genetics, Amsterdam, The Netherlands.

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August 2005

Cancer: two in one.

Authors:
Anton Berns

Nature 2005 Aug;436(7052):787-9

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http://dx.doi.org/10.1038/436787aDOI Listing
August 2005

Stem cells for lung cancer?

Authors:
Anton Berns

Cell 2005 Jun;121(6):811-3

Division of Molecular Genetics and Centre of Biomedical Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.cell.2005.06.004DOI Listing
June 2005

Mouse lung neuroendocrine carcinomas: distinct morphologies, same transcription factors.

Exp Lung Res 2005 Jan-Feb;31(1):37-55

Cell and Cancer Biology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20850, USA.

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April 2005

Mouse models for human lung cancer.

Genes Dev 2005 Mar;19(6):643-64

Division of Molecular Genetics and Center of Biomedical Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1101/gad.1284505DOI Listing
March 2005

Frat is dispensable for canonical Wnt signaling in mammals.

Genes Dev 2005 Feb 28;19(4):425-30. Epub 2005 Jan 28.

Division of Molecular Genetics, Centre of Biomedical Genetics, The Netherlands Cancer Institute, 1066 CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1101/gad.326705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC548942PMC
February 2005

Oncogene addiction: sometimes a temporary slavery.

Cancer Cell 2004 Dec;6(6):535-8

Division of Molecular Biology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S153561080400339
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http://dx.doi.org/10.1016/j.ccr.2004.12.002DOI Listing
December 2004

Synergy of Nf2 and p53 mutations in development of malignant tumours of neural crest origin.

Oncogene 2004 Aug;23(39):6541-7

Division of Molecular Genetics, Centre for Biomedical Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/sj.onc.1207858DOI Listing
August 2004

Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors.

Mol Cell Biol 2004 Jul;24(13):6104-15

Division of Molecular Genetics and Centre of Biomedical Genetics, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1128/MCB.24.13.6104-6115.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC480904PMC
July 2004

Characterization and functional analysis of the murine Frat2 gene.

J Biol Chem 2004 Jun 8;279(26):26967-74. Epub 2004 Apr 8.

Netherlands Cancer Institute, Division of Molecular Genetics and Centre of Biomedical Genetics, Amsterdam, The Netherlands.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M400439200
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http://dx.doi.org/10.1074/jbc.M400439200DOI Listing
June 2004

Good news for gene therapy.

Authors:
Anton Berns

N Engl J Med 2004 Apr;350(16):1679-80

Division of Molecular Genetics, the Netherlands Cancer Institute, Amsterdam.

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http://dx.doi.org/10.1056/NEJMcibr040341DOI Listing
April 2004

Retroviral insertional mutagenesis: tagging cancer pathways.

Adv Cancer Res 2003 ;88:53-99

Division of Molecular Genetics and Centre of Biomedical Genetics, Netherlands Cancer Institute 1066 CX, Amsterdam, The Netherlands.

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November 2003

The generation of a conditional reporter that enables bioluminescence imaging of Cre/loxP-dependent tumorigenesis in mice.

Cancer Res 2003 Nov;63(21):7042-6

Division of Molecular Genetics and Centre of Biomedical Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands.

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November 2003

Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model.

Cancer Cell 2003 Sep;4(3):181-9

Division of Molecular Genetics and Center of Biomedical Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.

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September 2003

Rb and p107 are required for normal cerebellar development and granule cell survival but not for Purkinje cell persistence.

Development 2003 Aug;130(15):3359-68

Institute of Clinical Pathology, University Hospital, Schmelzbergstrasse 12, 8091 Zürich, Switzerland.

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http://dx.doi.org/10.1242/dev.00553DOI Listing
August 2003

Tumour suppressors: timing will tell.

Authors:
Anton Berns

Nature 2003 Jul;424(6945):140-1

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http://dx.doi.org/10.1038/424140aDOI Listing
July 2003

Controlling gene expression in the urothelium using transgenic mice with inducible bladder specific Cre-lox recombination.

J Urol 2002 Dec;168(6):2641-4

Department of Urology, The Netherlands Cancer Institute and Centre of Biomedical Genetics, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1097/01.ju.0000030146.03639.90DOI Listing
December 2002

High-throughput retroviral tagging to identify components of specific signaling pathways in cancer.

Nat Genet 2002 Sep 19;32(1):153-9. Epub 2002 Aug 19.

Division of Molecular Genetics and Centre of Biomedical Genetics, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/ng950DOI Listing
September 2002

Proviral activation of the tumor suppressor E2a contributes to T cell lymphomagenesis in EmuMyc transgenic mice.

Oncogene 2002 Sep;21(43):6559-66

Division of Molecular Genetics and Centre of Biomedical Genetics, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/sj.onc.1205930DOI Listing
September 2002

Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis.

Proc Natl Acad Sci U S A 2002 Aug 31;99(17):11293-8. Epub 2002 Jul 31.

Division of Clinical Research and Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1073/pnas.162356099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC123250PMC
August 2002