Antoinette Hollestelle

Antoinette Hollestelle

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Antoinette Hollestelle

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Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer.

Authors:
Manuel A Ferreira Eric R Gamazon Fares Al-Ejeh Kristiina Aittomäki Irene L Andrulis Hoda Anton-Culver Adalgeir Arason Volker Arndt Kristan J Aronson Banu K Arun Ella Asseryanis Jacopo Azzollini Judith Balmaña Daniel R Barnes Daniel Barrowdale Matthias W Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Katarzyna Białkowska Carl Blomqvist Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Ake Borg Hiltrud Brauch Hermann Brenner Annegien Broeks Barbara Burwinkel Trinidad Caldés Maria A Caligo Daniele Campa Ian Campbell Federico Canzian Jonathan Carter Brian D Carter Jose E Castelao Jenny Chang-Claude Stephen J Chanock Hans Christiansen Wendy K Chung Kathleen B M Claes Christine L Clarke Fergus J Couch Angela Cox Simon S Cross Kamila Czene Mary B Daly Miguel de la Hoya Joe Dennis Peter Devilee Orland Diez Thilo Dörk Alison M Dunning Miriam Dwek Diana M Eccles Bent Ejlertsen Carolina Ellberg Christoph Engel Mikael Eriksson Peter A Fasching Olivia Fletcher Henrik Flyger Eitan Friedman Debra Frost Marike Gabrielson Manuela Gago-Dominguez Patricia A Ganz Susan M Gapstur Judy Garber Montserrat García-Closas José A García-Sáenz Mia M Gaudet Graham G Giles Gord Glendon Andrew K Godwin Mark S Goldberg David E Goldgar Anna González-Neira Mark H Greene Jacek Gronwald Pascal Guénel Christopher A Haiman Per Hall Ute Hamann Wei He Jane Heyworth Frans B L Hogervorst Antoinette Hollestelle Robert N Hoover John L Hopper Peter J Hulick Keith Humphreys Evgeny N Imyanitov Claudine Isaacs Milena Jakimovska Anna Jakubowska Paul A James Ramunas Janavicius Rachel C Jankowitz Esther M John Nichola Johnson Vijai Joseph Beth Y Karlan Elza Khusnutdinova Johanna I Kiiski Yon-Dschun Ko Michael E Jones Irene Konstantopoulou Vessela N Kristensen Yael Laitman Diether Lambrechts Conxi Lazaro Goska Leslie Jenny Lester Fabienne Lesueur Sara Lindström Jirong Long Jennifer T Loud Jan Lubiński Enes Makalic Arto Mannermaa Mehdi Manoochehri Sara Margolin Tabea Maurer Dimitrios Mavroudis Lesley McGuffog Alfons Meindl Usha Menon Kyriaki Michailidou Austin Miller Marco Montagna Fernando Moreno Lidia Moserle Anna Marie Mulligan Katherine L Nathanson Susan L Neuhausen Heli Nevanlinna Ines Nevelsteen Finn C Nielsen Liene Nikitina-Zake Robert L Nussbaum Kenneth Offit Edith Olah Olufunmilayo I Olopade Håkan Olsson Ana Osorio Janos Papp Tjoung-Won Park-Simon Michael T Parsons Inge Sokilde Pedersen Ana Peixoto Paolo Peterlongo Paul D P Pharoah Dijana Plaseska-Karanfilska Bruce Poppe Nadege Presneau Paolo Radice Johanna Rantala Gad Rennert Harvey A Risch Emmanouil Saloustros Kristin Sanden Elinor J Sawyer Marjanka K Schmidt Rita K Schmutzler Priyanka Sharma Xiao-Ou Shu Jacques Simard Christian F Singer Penny Soucy Melissa C Southey John J Spinelli Amanda B Spurdle Jennifer Stone Anthony J Swerdlow William J Tapper Jack A Taylor Manuel R Teixeira Mary Beth Terry Alex Teulé Mads Thomassen Kathrin Thöne Darcy L Thull Marc Tischkowitz Amanda E Toland Diana Torres Thérèse Truong Nadine Tung Celine M Vachon Christi J van Asperen Ans M W van den Ouweland Elizabeth J van Rensburg Ana Vega Alessandra Viel Qin Wang Barbara Wappenschmidt Jeffrey N Weitzel Camilla Wendt Robert Winqvist Xiaohong R Yang Drakoulis Yannoukakos Argyrios Ziogas Peter Kraft Antonis C Antoniou Wei Zheng Douglas F Easton Roger L Milne Jonathan Beesley Georgia Chenevix-Trench

Nat Commun 2019 04 15;10(1):1741. Epub 2019 Apr 15.

Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia.

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http://dx.doi.org/10.1038/s41467-018-08053-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465407PMC
April 2019

Genome-wide association study of germline variants and breast cancer-specific mortality.

Authors:
Maria Escala-Garcia Qi Guo Thilo Dörk Sander Canisius Renske Keeman Joe Dennis Jonathan Beesley Julie Lecarpentier Manjeet K Bolla Qin Wang Jean Abraham Irene L Andrulis Hoda Anton-Culver Volker Arndt Paul L Auer Matthias W Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Leslie Bernstein Carl Blomqvist Bram Boeckx Stig E Bojesen Bernardo Bonanni Anne-Lise Børresen-Dale Hiltrud Brauch Hermann Brenner Adam Brentnall Louise Brinton Per Broberg Ian W Brock Sara Y Brucker Barbara Burwinkel Carlos Caldas Trinidad Caldés Daniele Campa Federico Canzian Angel Carracedo Brian D Carter Jose E Castelao Jenny Chang-Claude Stephen J Chanock Georgia Chenevix-Trench Ting-Yuan David Cheng Suet-Feung Chin Christine L Clarke Emilie Cordina-Duverger Fergus J Couch David G Cox Angela Cox Simon S Cross Kamila Czene Mary B Daly Peter Devilee Janet A Dunn Alison M Dunning Lorraine Durcan Miriam Dwek Helena M Earl Arif B Ekici A Heather Eliassen Carolina Ellberg Christoph Engel Mikael Eriksson D Gareth Evans Jonine Figueroa Dieter Flesch-Janys Henrik Flyger Marike Gabrielson Manuela Gago-Dominguez Eva Galle Susan M Gapstur Montserrat García-Closas José A García-Sáenz Mia M Gaudet Angela George Vassilios Georgoulias Graham G Giles Gord Glendon David E Goldgar Anna González-Neira Grethe I Grenaker Alnæs Mervi Grip Pascal Guénel Lothar Haeberle Eric Hahnen Christopher A Haiman Niclas Håkansson Per Hall Ute Hamann Susan Hankinson Elaine F Harkness Patricia A Harrington Steven N Hart Jaana M Hartikainen Alexander Hein Peter Hillemanns Louise Hiller Bernd Holleczek Antoinette Hollestelle Maartje J Hooning Robert N Hoover John L Hopper Anthony Howell Guanmengqian Huang Keith Humphreys David J Hunter Wolfgang Janni Esther M John Michael E Jones Arja Jukkola-Vuorinen Audrey Jung Rudolf Kaaks Maria Kabisch Katarzyna Kaczmarek Michael J Kerin Sofia Khan Elza Khusnutdinova Johanna I Kiiski Cari M Kitahara Julia A Knight Yon-Dschun Ko Linetta B Koppert Veli-Matti Kosma Peter Kraft Vessela N Kristensen Ute Krüger Tabea Kühl Diether Lambrechts Loic Le Marchand Eunjung Lee Flavio Lejbkowicz Lian Li Annika Lindblom Sara Lindström Martha Linet Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jan Lubiński Michael P Lux Robert J MacInnis Melanie Maierthaler Tom Maishman Enes Makalic Arto Mannermaa Mehdi Manoochehri Siranoush Manoukian Sara Margolin Maria Elena Martinez Dimitrios Mavroudis Catriona McLean Alfons Meindl Pooja Middha Nicola Miller Roger L Milne Fernando Moreno Anna Marie Mulligan Claire Mulot Rami Nassir Susan L Neuhausen William T Newman Sune F Nielsen Børge G Nordestgaard Aaron Norman Håkan Olsson Nick Orr V Shane Pankratz Tjoung-Won Park-Simon Jose I A Perez Clara Pérez-Barrios Paolo Peterlongo Christos Petridis Mila Pinchev Karoliona Prajzendanc Ross Prentice Nadege Presneau Darya Prokofieva Katri Pylkäs Brigitte Rack Paolo Radice Dhanya Ramachandran Gadi Rennert Hedy S Rennert Valerie Rhenius Atocha Romero Rebecca Roylance Emmanouil Saloustros Elinor J Sawyer Daniel F Schmidt Rita K Schmutzler Andreas Schneeweiss Minouk J Schoemaker Fredrick Schumacher Lukas Schwentner Rodney J Scott Christopher Scott Caroline Seynaeve Mitul Shah Jacques Simard Ann Smeets Christof Sohn Melissa C Southey Anthony J Swerdlow Aline Talhouk Rulla M Tamimi William J Tapper Manuel R Teixeira Maria Tengström Mary Beth Terry Kathrin Thöne Rob A E M Tollenaar Ian Tomlinson Diana Torres Thérèse Truong Constance Turman Clare Turnbull Hans-Ulrich Ulmer Michael Untch Celine Vachon Christi J van Asperen Ans M W van den Ouweland Elke M van Veen Camilla Wendt Alice S Whittemore Walter Willett Robert Winqvist Alicja Wolk Xiaohong R Yang Yan Zhang Douglas F Easton Peter A Fasching Heli Nevanlinna Diana M Eccles Paul D P Pharoah Marjanka K Schmidt

Br J Cancer 2019 Mar 21;120(6):647-657. Epub 2019 Feb 21.

The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Division of Molecular Pathology, Amsterdam, The Netherlands.

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http://www.nature.com/articles/s41416-019-0393-x
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http://dx.doi.org/10.1038/s41416-019-0393-xDOI Listing
March 2019

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.

Authors:
Nasim Mavaddat Kyriaki Michailidou Joe Dennis Michael Lush Laura Fachal Andrew Lee Jonathan P Tyrer Ting-Huei Chen Qin Wang Manjeet K Bolla Xin Yang Muriel A Adank Thomas Ahearn Kristiina Aittomäki Jamie Allen Irene L Andrulis Hoda Anton-Culver Natalia N Antonenkova Volker Arndt Kristan J Aronson Paul L Auer Päivi Auvinen Myrto Barrdahl Laura E Beane Freeman Matthias W Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Leslie Bernstein Carl Blomqvist Natalia V Bogdanova Stig E Bojesen Bernardo Bonanni Anne-Lise Børresen-Dale Hiltrud Brauch Michael Bremer Hermann Brenner Adam Brentnall Ian W Brock Angela Brooks-Wilson Sara Y Brucker Thomas Brüning Barbara Burwinkel Daniele Campa Brian D Carter Jose E Castelao Stephen J Chanock Rowan Chlebowski Hans Christiansen Christine L Clarke J Margriet Collée Emilie Cordina-Duverger Sten Cornelissen Fergus J Couch Angela Cox Simon S Cross Kamila Czene Mary B Daly Peter Devilee Thilo Dörk Isabel Dos-Santos-Silva Martine Dumont Lorraine Durcan Miriam Dwek Diana M Eccles Arif B Ekici A Heather Eliassen Carolina Ellberg Christoph Engel Mikael Eriksson D Gareth Evans Peter A Fasching Jonine Figueroa Olivia Fletcher Henrik Flyger Asta Försti Lin Fritschi Marike Gabrielson Manuela Gago-Dominguez Susan M Gapstur José A García-Sáenz Mia M Gaudet Vassilios Georgoulias Graham G Giles Irina R Gilyazova Gord Glendon Mark S Goldberg David E Goldgar Anna González-Neira Grethe I Grenaker Alnæs Mervi Grip Jacek Gronwald Anne Grundy Pascal Guénel Lothar Haeberle Eric Hahnen Christopher A Haiman Niclas Håkansson Ute Hamann Susan E Hankinson Elaine F Harkness Steven N Hart Wei He Alexander Hein Jane Heyworth Peter Hillemanns Antoinette Hollestelle Maartje J Hooning Robert N Hoover John L Hopper Anthony Howell Guanmengqian Huang Keith Humphreys David J Hunter Milena Jakimovska Anna Jakubowska Wolfgang Janni Esther M John Nichola Johnson Michael E Jones Arja Jukkola-Vuorinen Audrey Jung Rudolf Kaaks Katarzyna Kaczmarek Vesa Kataja Renske Keeman Michael J Kerin Elza Khusnutdinova Johanna I Kiiski Julia A Knight Yon-Dschun Ko Veli-Matti Kosma Stella Koutros Vessela N Kristensen Ute Krüger Tabea Kühl Diether Lambrechts Loic Le Marchand Eunjung Lee Flavio Lejbkowicz Jenna Lilyquist Annika Lindblom Sara Lindström Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jirong Long Jan Lubiński Michael P Lux Robert J MacInnis Tom Maishman Enes Makalic Ivana Maleva Kostovska Arto Mannermaa Siranoush Manoukian Sara Margolin John W M Martens Maria Elena Martinez Dimitrios Mavroudis Catriona McLean Alfons Meindl Usha Menon Pooja Middha Nicola Miller Fernando Moreno Anna Marie Mulligan Claire Mulot Victor M Muñoz-Garzon Susan L Neuhausen Heli Nevanlinna Patrick Neven William G Newman Sune F Nielsen Børge G Nordestgaard Aaron Norman Kenneth Offit Janet E Olson Håkan Olsson Nick Orr V Shane Pankratz Tjoung-Won Park-Simon Jose I A Perez Clara Pérez-Barrios Paolo Peterlongo Julian Peto Mila Pinchev Dijana Plaseska-Karanfilska Eric C Polley Ross Prentice Nadege Presneau Darya Prokofyeva Kristen Purrington Katri Pylkäs Brigitte Rack Paolo Radice Rohini Rau-Murthy Gad Rennert Hedy S Rennert Valerie Rhenius Mark Robson Atocha Romero Kathryn J Ruddy Matthias Ruebner Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Daniel F Schmidt Rita K Schmutzler Andreas Schneeweiss Minouk J Schoemaker Fredrick Schumacher Peter Schürmann Lukas Schwentner Christopher Scott Rodney J Scott Caroline Seynaeve Mitul Shah Mark E Sherman Martha J Shrubsole Xiao-Ou Shu Susan Slager Ann Smeets Christof Sohn Penny Soucy Melissa C Southey John J Spinelli Christa Stegmaier Jennifer Stone Anthony J Swerdlow Rulla M Tamimi William J Tapper Jack A Taylor Mary Beth Terry Kathrin Thöne Rob A E M Tollenaar Ian Tomlinson Thérèse Truong Maria Tzardi Hans-Ulrich Ulmer Michael Untch Celine M Vachon Elke M van Veen Joseph Vijai Clarice R Weinberg Camilla Wendt Alice S Whittemore Hans Wildiers Walter Willett Robert Winqvist Alicja Wolk Xiaohong R Yang Drakoulis Yannoukakos Yan Zhang Wei Zheng Argyrios Ziogas Alison M Dunning Deborah J Thompson Georgia Chenevix-Trench Jenny Chang-Claude Marjanka K Schmidt Per Hall Roger L Milne Paul D P Pharoah Antonis C Antoniou Nilanjan Chatterjee Peter Kraft Montserrat García-Closas Jacques Simard Douglas F Easton

Am J Hum Genet 2019 Jan 13;104(1):21-34. Epub 2018 Dec 13.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S00029297183040
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http://dx.doi.org/10.1016/j.ajhg.2018.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323553PMC
January 2019

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk.

Authors:
Yingchang Lu Alicia Beeghly-Fadiel Lang Wu Xingyi Guo Bingshan Li Joellen M Schildkraut Hae Kyung Im Yian A Chen Jennifer B Permuth Brett M Reid Jamie K Teer Kirsten B Moysich Irene L Andrulis Hoda Anton-Culver Banu K Arun Elisa V Bandera Rosa B Barkardottir Daniel R Barnes Javier Benitez Line Bjorge James Brenton Ralf Butzow Trinidad Caldes Maria A Caligo Ian Campbell Jenny Chang-Claude Kathleen B M Claes Fergus J Couch Daniel W Cramer Mary B Daly Anna deFazio Joe Dennis Orland Diez Susan M Domchek Thilo Dörk Douglas F Easton Diana M Eccles Peter A Fasching Renée T Fortner George Fountzilas Eitan Friedman Patricia A Ganz Judy Garber Graham G Giles Andrew K Godwin David E Goldgar Marc T Goodman Mark H Greene Jacek Gronwald Ute Hamann Florian Heitz Michelle A T Hildebrandt Claus K Høgdall Antoinette Hollestelle Peter J Hulick David G Huntsman Evgeny N Imyanitov Claudine Isaacs Anna Jakubowska Paul James Beth Y Karlan Linda E Kelemen Lambertus A Kiemeney Susanne K Kjaer Ava Kwong Nhu D Le Goska Leslie Fabienne Lesueur Douglas A Levine Amalia Mattiello Taymaa May Lesley McGuffog Iain A McNeish Melissa A Merritt Francesmary Modugno Marco Montagna Susan L Neuhausen Heli Nevanlinna Finn C Nielsen Liene Nikitina-Zake Robert L Nussbaum Kenneth Offit Edith Olah Olufunmilayo I Olopade Sara H Olson Håkan Olsson Ana Osorio Sue K Park Michael T Parsons Petra H M Peeters Tanja Pejovic Paolo Peterlongo Catherine M Phelan Miquel Angel Pujana Susan J Ramus Gad Rennert Harvey Risch Gustavo C Rodriguez Cristina Rodríguez-Antona Isabelle Romieu Matti A Rookus Mary Anne Rossing Iwona K Rzepecka Dale P Sandler Rita K Schmutzler Veronica W Setiawan Priyanka Sharma Weiva Sieh Jacques Simard Christian F Singer Honglin Song Melissa C Southey Amanda B Spurdle Rebecca Sutphen Anthony J Swerdlow Manuel R Teixeira Soo H Teo Mads Thomassen Marc Tischkowitz Amanda E Toland Antonia Trichopoulou Nadine Tung Shelley S Tworoger Elizabeth J van Rensburg Adriaan Vanderstichele Ana Vega Digna Velez Edwards Penelope M Webb Jeffrey N Weitzel Nicolas Wentzensen Emily White Alicja Wolk Anna H Wu Drakoulis Yannoukakos Kristin K Zorn Simon A Gayther Antonis C Antoniou Andrew Berchuck Ellen L Goode Georgia Chenevix-Trench Thomas A Sellers Paul D P Pharoah Wei Zheng Jirong Long

Cancer Res 2018 Sep 27;78(18):5419-5430. Epub 2018 Jul 27.

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-0951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139053PMC
September 2018

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer.

Authors:
Lang Wu Wei Shi Jirong Long Xingyi Guo Kyriaki Michailidou Jonathan Beesley Manjeet K Bolla Xiao-Ou Shu Yingchang Lu Qiuyin Cai Fares Al-Ejeh Esdy Rozali Qin Wang Joe Dennis Bingshan Li Chenjie Zeng Helian Feng Alexander Gusev Richard T Barfield Irene L Andrulis Hoda Anton-Culver Volker Arndt Kristan J Aronson Paul L Auer Myrto Barrdahl Caroline Baynes Matthias W Beckmann Javier Benitez Marina Bermisheva Carl Blomqvist Natalia V Bogdanova Stig E Bojesen Hiltrud Brauch Hermann Brenner Louise Brinton Per Broberg Sara Y Brucker Barbara Burwinkel Trinidad Caldés Federico Canzian Brian D Carter J Esteban Castelao Jenny Chang-Claude Xiaoqing Chen Ting-Yuan David Cheng Hans Christiansen Christine L Clarke Margriet Collée Sten Cornelissen Fergus J Couch David Cox Angela Cox Simon S Cross Julie M Cunningham Kamila Czene Mary B Daly Peter Devilee Kimberly F Doheny Thilo Dörk Isabel Dos-Santos-Silva Martine Dumont Miriam Dwek Diana M Eccles Ursula Eilber A Heather Eliassen Christoph Engel Mikael Eriksson Laura Fachal Peter A Fasching Jonine Figueroa Dieter Flesch-Janys Olivia Fletcher Henrik Flyger Lin Fritschi Marike Gabrielson Manuela Gago-Dominguez Susan M Gapstur Montserrat García-Closas Mia M Gaudet Maya Ghoussaini Graham G Giles Mark S Goldberg David E Goldgar Anna González-Neira Pascal Guénel Eric Hahnen Christopher A Haiman Niclas Håkansson Per Hall Emily Hallberg Ute Hamann Patricia Harrington Alexander Hein Belynda Hicks Peter Hillemanns Antoinette Hollestelle Robert N Hoover John L Hopper Guanmengqian Huang Keith Humphreys David J Hunter Anna Jakubowska Wolfgang Janni Esther M John Nichola Johnson Kristine Jones Michael E Jones Audrey Jung Rudolf Kaaks Michael J Kerin Elza Khusnutdinova Veli-Matti Kosma Vessela N Kristensen Diether Lambrechts Loic Le Marchand Jingmei Li Sara Lindström Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jan Lubinski Craig Luccarini Michael P Lux Robert J MacInnis Tom Maishman Ivana Maleva Kostovska Arto Mannermaa JoAnn E Manson Sara Margolin Dimitrios Mavroudis Hanne Meijers-Heijboer Alfons Meindl Usha Menon Jeffery Meyer Anna Marie Mulligan Susan L Neuhausen Heli Nevanlinna Patrick Neven Sune F Nielsen Børge G Nordestgaard Olufunmilayo I Olopade Janet E Olson Håkan Olsson Paolo Peterlongo Julian Peto Dijana Plaseska-Karanfilska Ross Prentice Nadege Presneau Katri Pylkäs Brigitte Rack Paolo Radice Nazneen Rahman Gad Rennert Hedy S Rennert Valerie Rhenius Atocha Romero Jane Romm Anja Rudolph Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Marjanka K Schmidt Rita K Schmutzler Andreas Schneeweiss Rodney J Scott Christopher G Scott Sheila Seal Mitul Shah Martha J Shrubsole Ann Smeets Melissa C Southey John J Spinelli Jennifer Stone Harald Surowy Anthony J Swerdlow Rulla M Tamimi William Tapper Jack A Taylor Mary Beth Terry Daniel C Tessier Abigail Thomas Kathrin Thöne Rob A E M Tollenaar Diana Torres Thérèse Truong Michael Untch Celine Vachon David Van Den Berg Daniel Vincent Quinten Waisfisz Clarice R Weinberg Camilla Wendt Alice S Whittemore Hans Wildiers Walter C Willett Robert Winqvist Alicja Wolk Lucy Xia Xiaohong R Yang Argyrios Ziogas Elad Ziv Alison M Dunning Paul D P Pharoah Jacques Simard Roger L Milne Stacey L Edwards Peter Kraft Douglas F Easton Georgia Chenevix-Trench Wei Zheng

Nat Genet 2018 07 18;50(7):968-978. Epub 2018 Jun 18.

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.1038/s41588-018-0132-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314198PMC
July 2018

The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity.

Authors:
Mara Colombo Irene Lòpez-Perolio Huong D Meeks Laura Caleca Michael T Parsons Hongyan Li Giovanna De Vecchi Emma Tudini Claudia Foglia Patrizia Mondini Siranoush Manoukian Raquel Behar Encarna B Gómez Garcia Alfons Meindl Marco Montagna Dieter Niederacher Ane Y Schmidt Liliana Varesco Barbara Wappenschmidt Manjeet K Bolla Joe Dennis Kyriaki Michailidou Qin Wang Kristiina Aittomäki Irene L Andrulis Hoda Anton-Culver Volker Arndt Matthias W Beckmann Alicia Beeghly-Fadel Javier Benitez Bram Boeckx Natalia V Bogdanova Stig E Bojesen Bernardo Bonanni Hiltrud Brauch Hermann Brenner Barbara Burwinkel Jenny Chang-Claude Don M Conroy Fergus J Couch Angela Cox Simon S Cross Kamila Czene Peter Devilee Thilo Dörk Mikael Eriksson Peter A Fasching Jonine Figueroa Olivia Fletcher Henrik Flyger Marike Gabrielson Montserrat García-Closas Graham G Giles Anna González-Neira Pascal Guénel Christopher A Haiman Per Hall Ute Hamann Mikael Hartman Jan Hauke Antoinette Hollestelle John L Hopper Anna Jakubowska Audrey Jung Veli-Matti Kosma Diether Lambrechts Loid Le Marchand Annika Lindblom Jan Lubinski Arto Mannermaa Sara Margolin Hui Miao Roger L Milne Susan L Neuhausen Heli Nevanlinna Janet E Olson Paolo Peterlongo Julian Peto Katri Pylkäs Elinor J Sawyer Marjanka K Schmidt Rita K Schmutzler Andreas Schneeweiss Minouk J Schoemaker Mee Hoong See Melissa C Southey Anthony Swerdlow Soo H Teo Amanda E Toland Ian Tomlinson Thérèse Truong Christi J van Asperen Ans M W van den Ouweland Lizet E van der Kolk Robert Winqvist Drakoulis Yannoukakos Wei Zheng Alison M Dunning Douglas F Easton Alex Henderson Frans B L Hogervorst Louise Izatt Kenneth Offitt Lucy E Side Elizabeth J van Rensburg Study Embrace Study Hebon Lesley McGuffog Antonis C Antoniou Georgia Chenevix-Trench Amanda B Spurdle David E Goldgar Miguel de la Hoya Paolo Radice

Hum Mutat 2018 05 6;39(5):729-741. Epub 2018 Apr 6.

Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT), Milan, Italy.

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http://dx.doi.org/10.1002/humu.23411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947288PMC
May 2018

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

Authors:
Roger L Milne Karoline B Kuchenbaecker Kyriaki Michailidou Jonathan Beesley Siddhartha Kar Sara Lindström Shirley Hui Audrey Lemaçon Penny Soucy Joe Dennis Xia Jiang Asha Rostamianfar Hilary Finucane Manjeet K Bolla Lesley McGuffog Qin Wang Cora M Aalfs Marcia Adams Julian Adlard Simona Agata Shahana Ahmed Habibul Ahsan Kristiina Aittomäki Fares Al-Ejeh Jamie Allen Christine B Ambrosone Christopher I Amos Irene L Andrulis Hoda Anton-Culver Natalia N Antonenkova Volker Arndt Norbert Arnold Kristan J Aronson Bernd Auber Paul L Auer Margreet G E M Ausems Jacopo Azzollini François Bacot Judith Balmaña Monica Barile Laure Barjhoux Rosa B Barkardottir Myrto Barrdahl Daniel Barnes Daniel Barrowdale Caroline Baynes Matthias W Beckmann Javier Benitez Marina Bermisheva Leslie Bernstein Yves-Jean Bignon Kathleen R Blazer Marinus J Blok Carl Blomqvist William Blot Kristie Bobolis Bram Boeckx Natalia V Bogdanova Anders Bojesen Stig E Bojesen Bernardo Bonanni Anne-Lise Børresen-Dale Aniko Bozsik Angela R Bradbury Judith S Brand Hiltrud Brauch Hermann Brenner Brigitte Bressac-de Paillerets Carole Brewer Louise Brinton Per Broberg Angela Brooks-Wilson Joan Brunet Thomas Brüning Barbara Burwinkel Saundra S Buys Jinyoung Byun Qiuyin Cai Trinidad Caldés Maria A Caligo Ian Campbell Federico Canzian Olivier Caron Angel Carracedo Brian D Carter J Esteban Castelao Laurent Castera Virginie Caux-Moncoutier Salina B Chan Jenny Chang-Claude Stephen J Chanock Xiaoqing Chen Ting-Yuan David Cheng Jocelyne Chiquette Hans Christiansen Kathleen B M Claes Christine L Clarke Thomas Conner Don M Conroy Jackie Cook Emilie Cordina-Duverger Sten Cornelissen Isabelle Coupier Angela Cox David G Cox Simon S Cross Katarina Cuk Julie M Cunningham Kamila Czene Mary B Daly Francesca Damiola Hatef Darabi Rosemarie Davidson Kim De Leeneer Peter Devilee Ed Dicks Orland Diez Yuan Chun Ding Nina Ditsch Kimberly F Doheny Susan M Domchek Cecilia M Dorfling Thilo Dörk Isabel Dos-Santos-Silva Stéphane Dubois Pierre-Antoine Dugué Martine Dumont Alison M Dunning Lorraine Durcan Miriam Dwek Bernd Dworniczak Diana Eccles Ros Eeles Hans Ehrencrona Ursula Eilber Bent Ejlertsen Arif B Ekici A Heather Eliassen Christoph Engel Mikael Eriksson Laura Fachal Laurence Faivre Peter A Fasching Ulrike Faust Jonine Figueroa Dieter Flesch-Janys Olivia Fletcher Henrik Flyger William D Foulkes Eitan Friedman Lin Fritschi Debra Frost Marike Gabrielson Pragna Gaddam Marilie D Gammon Patricia A Ganz Susan M Gapstur Judy Garber Vanesa Garcia-Barberan José A García-Sáenz Mia M Gaudet Marion Gauthier-Villars Andrea Gehrig Vassilios Georgoulias Anne-Marie Gerdes Graham G Giles Gord Glendon Andrew K Godwin Mark S Goldberg David E Goldgar Anna González-Neira Paul Goodfellow Mark H Greene Grethe I Grenaker Alnæs Mervi Grip Jacek Gronwald Anne Grundy Daphne Gschwantler-Kaulich Pascal Guénel Qi Guo Lothar Haeberle Eric Hahnen Christopher A Haiman Niclas Håkansson Emily Hallberg Ute Hamann Nathalie Hamel Susan Hankinson Thomas V O Hansen Patricia Harrington Steven N Hart Jaana M Hartikainen Catherine S Healey Alexander Hein Sonja Helbig Alex Henderson Jane Heyworth Belynda Hicks Peter Hillemanns Shirley Hodgson Frans B Hogervorst Antoinette Hollestelle Maartje J Hooning Bob Hoover John L Hopper Chunling Hu Guanmengqian Huang Peter J Hulick Keith Humphreys David J Hunter Evgeny N Imyanitov Claudine Isaacs Motoki Iwasaki Louise Izatt Anna Jakubowska Paul James Ramunas Janavicius Wolfgang Janni Uffe Birk Jensen Esther M John Nichola Johnson Kristine Jones Michael Jones Arja Jukkola-Vuorinen Rudolf Kaaks Maria Kabisch Katarzyna Kaczmarek Daehee Kang Karin Kast Renske Keeman Michael J Kerin Carolien M Kets Machteld Keupers Sofia Khan Elza Khusnutdinova Johanna I Kiiski Sung-Won Kim Julia A Knight Irene Konstantopoulou Veli-Matti Kosma Vessela N Kristensen Torben A Kruse Ava Kwong Anne-Vibeke Lænkholm Yael Laitman Fiona Lalloo Diether Lambrechts Keren Landsman Christine Lasset Conxi Lazaro Loic Le Marchand Julie Lecarpentier Andrew Lee Eunjung Lee Jong Won Lee Min Hyuk Lee Flavio Lejbkowicz Fabienne Lesueur Jingmei Li Jenna Lilyquist Anne Lincoln Annika Lindblom Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jirong Long Jennifer T Loud Jan Lubinski Craig Luccarini Michael Lush Robert J MacInnis Tom Maishman Enes Makalic Ivana Maleva Kostovska Kathleen E Malone Siranoush Manoukian JoAnn E Manson Sara Margolin John W M Martens Maria Elena Martinez Keitaro Matsuo Dimitrios Mavroudis Sylvie Mazoyer Catriona McLean Hanne Meijers-Heijboer Primitiva Menéndez Jeffery Meyer Hui Miao Austin Miller Nicola Miller Gillian Mitchell Marco Montagna Kenneth Muir Anna Marie Mulligan Claire Mulot Sue Nadesan Katherine L Nathanson Susan L Neuhausen Heli Nevanlinna Ines Nevelsteen Dieter Niederacher Sune F Nielsen Børge G Nordestgaard Aaron Norman Robert L Nussbaum Edith Olah Olufunmilayo I Olopade Janet E Olson Curtis Olswold Kai-Ren Ong Jan C Oosterwijk Nick Orr Ana Osorio V Shane Pankratz Laura Papi Tjoung-Won Park-Simon Ylva Paulsson-Karlsson Rachel Lloyd Inge Søkilde Pedersen Bernard Peissel Ana Peixoto Jose I A Perez Paolo Peterlongo Julian Peto Georg Pfeiler Catherine M Phelan Mila Pinchev Dijana Plaseska-Karanfilska Bruce Poppe Mary E Porteous Ross Prentice Nadege Presneau Darya Prokofieva Elizabeth Pugh Miquel Angel Pujana Katri Pylkäs Brigitte Rack Paolo Radice Nazneen Rahman Johanna Rantala Christine Rappaport-Fuerhauser Gad Rennert Hedy S Rennert Valerie Rhenius Kerstin Rhiem Andrea Richardson Gustavo C Rodriguez Atocha Romero Jane Romm Matti A Rookus Anja Rudolph Thomas Ruediger Emmanouil Saloustros Joyce Sanders Dale P Sandler Suleeporn Sangrajrang Elinor J Sawyer Daniel F Schmidt Minouk J Schoemaker Fredrick Schumacher Peter Schürmann Lukas Schwentner Christopher Scott Rodney J Scott Sheila Seal Leigha Senter Caroline Seynaeve Mitul Shah Priyanka Sharma Chen-Yang Shen Xin Sheng Hermela Shimelis Martha J Shrubsole Xiao-Ou Shu Lucy E Side Christian F Singer Christof Sohn Melissa C Southey John J Spinelli Amanda B Spurdle Christa Stegmaier Dominique Stoppa-Lyonnet Grzegorz Sukiennicki Harald Surowy Christian Sutter Anthony Swerdlow Csilla I Szabo Rulla M Tamimi Yen Y Tan Jack A Taylor Maria-Isabel Tejada Maria Tengström Soo H Teo Mary B Terry Daniel C Tessier Alex Teulé Kathrin Thöne Darcy L Thull Maria Grazia Tibiletti Laima Tihomirova Marc Tischkowitz Amanda E Toland Rob A E M Tollenaar Ian Tomlinson Ling Tong Diana Torres Martine Tranchant Thérèse Truong Kathy Tucker Nadine Tung Jonathan Tyrer Hans-Ulrich Ulmer Celine Vachon Christi J van Asperen David Van Den Berg Ans M W van den Ouweland Elizabeth J van Rensburg Liliana Varesco Raymonda Varon-Mateeva Ana Vega Alessandra Viel Joseph Vijai Daniel Vincent Jason Vollenweider Lisa Walker Zhaoming Wang Shan Wang-Gohrke Barbara Wappenschmidt Clarice R Weinberg Jeffrey N Weitzel Camilla Wendt Jelle Wesseling Alice S Whittemore Juul T Wijnen Walter Willett Robert Winqvist Alicja Wolk Anna H Wu Lucy Xia Xiaohong R Yang Drakoulis Yannoukakos Daniela Zaffaroni Wei Zheng Bin Zhu Argyrios Ziogas Elad Ziv Kristin K Zorn Manuela Gago-Dominguez Arto Mannermaa Håkan Olsson Manuel R Teixeira Jennifer Stone Kenneth Offit Laura Ottini Sue K Park Mads Thomassen Per Hall Alfons Meindl Rita K Schmutzler Arnaud Droit Gary D Bader Paul D P Pharoah Fergus J Couch Douglas F Easton Peter Kraft Georgia Chenevix-Trench Montserrat García-Closas Marjanka K Schmidt Antonis C Antoniou Jacques Simard

Nat Genet 2017 Dec 23;49(12):1767-1778. Epub 2017 Oct 23.

Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808456PMC
December 2017

Association analysis identifies 65 new breast cancer risk loci.

Authors:
Kyriaki Michailidou Sara Lindström Joe Dennis Jonathan Beesley Shirley Hui Siddhartha Kar Audrey Lemaçon Penny Soucy Dylan Glubb Asha Rostamianfar Manjeet K Bolla Qin Wang Jonathan Tyrer Ed Dicks Andrew Lee Zhaoming Wang Jamie Allen Renske Keeman Ursula Eilber Juliet D French Xiao Qing Chen Laura Fachal Karen McCue Amy E McCart Reed Maya Ghoussaini Jason S Carroll Xia Jiang Hilary Finucane Marcia Adams Muriel A Adank Habibul Ahsan Kristiina Aittomäki Hoda Anton-Culver Natalia N Antonenkova Volker Arndt Kristan J Aronson Banu Arun Paul L Auer François Bacot Myrto Barrdahl Caroline Baynes Matthias W Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Leslie Bernstein Carl Blomqvist Natalia V Bogdanova Stig E Bojesen Bernardo Bonanni Anne-Lise Børresen-Dale Judith S Brand Hiltrud Brauch Paul Brennan Hermann Brenner Louise Brinton Per Broberg Ian W Brock Annegien Broeks Angela Brooks-Wilson Sara Y Brucker Thomas Brüning Barbara Burwinkel Katja Butterbach Qiuyin Cai Hui Cai Trinidad Caldés Federico Canzian Angel Carracedo Brian D Carter Jose E Castelao Tsun L Chan Ting-Yuan David Cheng Kee Seng Chia Ji-Yeob Choi Hans Christiansen Christine L Clarke Margriet Collée Don M Conroy Emilie Cordina-Duverger Sten Cornelissen David G Cox Angela Cox Simon S Cross Julie M Cunningham Kamila Czene Mary B Daly Peter Devilee Kimberly F Doheny Thilo Dörk Isabel Dos-Santos-Silva Martine Dumont Lorraine Durcan Miriam Dwek Diana M Eccles Arif B Ekici A Heather Eliassen Carolina Ellberg Mingajeva Elvira Christoph Engel Mikael Eriksson Peter A Fasching Jonine Figueroa Dieter Flesch-Janys Olivia Fletcher Henrik Flyger Lin Fritschi Valerie Gaborieau Marike Gabrielson Manuela Gago-Dominguez Yu-Tang Gao Susan M Gapstur José A García-Sáenz Mia M Gaudet Vassilios Georgoulias Graham G Giles Gord Glendon Mark S Goldberg David E Goldgar Anna González-Neira Grethe I Grenaker Alnæs Mervi Grip Jacek Gronwald Anne Grundy Pascal Guénel Lothar Haeberle Eric Hahnen Christopher A Haiman Niclas Håkansson Ute Hamann Nathalie Hamel Susan Hankinson Patricia Harrington Steven N Hart Jaana M Hartikainen Mikael Hartman Alexander Hein Jane Heyworth Belynda Hicks Peter Hillemanns Dona N Ho Antoinette Hollestelle Maartje J Hooning Robert N Hoover John L Hopper Ming-Feng Hou Chia-Ni Hsiung Guanmengqian Huang Keith Humphreys Junko Ishiguro Hidemi Ito Motoki Iwasaki Hiroji Iwata Anna Jakubowska Wolfgang Janni Esther M John Nichola Johnson Kristine Jones Michael Jones Arja Jukkola-Vuorinen Rudolf Kaaks Maria Kabisch Katarzyna Kaczmarek Daehee Kang Yoshio Kasuga Michael J Kerin Sofia Khan Elza Khusnutdinova Johanna I Kiiski Sung-Won Kim Julia A Knight Veli-Matti Kosma Vessela N Kristensen Ute Krüger Ava Kwong Diether Lambrechts Loic Le Marchand Eunjung Lee Min Hyuk Lee Jong Won Lee Chuen Neng Lee Flavio Lejbkowicz Jingmei Li Jenna Lilyquist Annika Lindblom Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jirong Long Artitaya Lophatananon Jan Lubinski Craig Luccarini Michael P Lux Edmond S K Ma Robert J MacInnis Tom Maishman Enes Makalic Kathleen E Malone Ivana Maleva Kostovska Arto Mannermaa Siranoush Manoukian JoAnn E Manson Sara Margolin Shivaani Mariapun Maria Elena Martinez Keitaro Matsuo Dimitrios Mavroudis James McKay Catriona McLean Hanne Meijers-Heijboer Alfons Meindl Primitiva Menéndez Usha Menon Jeffery Meyer Hui Miao Nicola Miller Nur Aishah Mohd Taib Kenneth Muir Anna Marie Mulligan Claire Mulot Susan L Neuhausen Heli Nevanlinna Patrick Neven Sune F Nielsen Dong-Young Noh Børge G Nordestgaard Aaron Norman Olufunmilayo I Olopade Janet E Olson Håkan Olsson Curtis Olswold Nick Orr V Shane Pankratz Sue K Park Tjoung-Won Park-Simon Rachel Lloyd Jose I A Perez Paolo Peterlongo Julian Peto Kelly-Anne Phillips Mila Pinchev Dijana Plaseska-Karanfilska Ross Prentice Nadege Presneau Darya Prokofyeva Elizabeth Pugh Katri Pylkäs Brigitte Rack Paolo Radice Nazneen Rahman Gadi Rennert Hedy S Rennert Valerie Rhenius Atocha Romero Jane Romm Kathryn J Ruddy Thomas Rüdiger Anja Rudolph Matthias Ruebner Emiel J T Rutgers Emmanouil Saloustros Dale P Sandler Suleeporn Sangrajrang Elinor J Sawyer Daniel F Schmidt Rita K Schmutzler Andreas Schneeweiss Minouk J Schoemaker Fredrick Schumacher Peter Schürmann Rodney J Scott Christopher Scott Sheila Seal Caroline Seynaeve Mitul Shah Priyanka Sharma Chen-Yang Shen Grace Sheng Mark E Sherman Martha J Shrubsole Xiao-Ou Shu Ann Smeets Christof Sohn Melissa C Southey John J Spinelli Christa Stegmaier Sarah Stewart-Brown Jennifer Stone Daniel O Stram Harald Surowy Anthony Swerdlow Rulla Tamimi Jack A Taylor Maria Tengström Soo H Teo Mary Beth Terry Daniel C Tessier Somchai Thanasitthichai Kathrin Thöne Rob A E M Tollenaar Ian Tomlinson Ling Tong Diana Torres Thérèse Truong Chiu-Chen Tseng Shoichiro Tsugane Hans-Ulrich Ulmer Giske Ursin Michael Untch Celine Vachon Christi J van Asperen David Van Den Berg Ans M W van den Ouweland Lizet van der Kolk Rob B van der Luijt Daniel Vincent Jason Vollenweider Quinten Waisfisz Shan Wang-Gohrke Clarice R Weinberg Camilla Wendt Alice S Whittemore Hans Wildiers Walter Willett Robert Winqvist Alicja Wolk Anna H Wu Lucy Xia Taiki Yamaji Xiaohong R Yang Cheng Har Yip Keun-Young Yoo Jyh-Cherng Yu Wei Zheng Ying Zheng Bin Zhu Argyrios Ziogas Elad Ziv Sunil R Lakhani Antonis C Antoniou Arnaud Droit Irene L Andrulis Christopher I Amos Fergus J Couch Paul D P Pharoah Jenny Chang-Claude Per Hall David J Hunter Roger L Milne Montserrat García-Closas Marjanka K Schmidt Stephen J Chanock Alison M Dunning Stacey L Edwards Gary D Bader Georgia Chenevix-Trench Jacques Simard Peter Kraft Douglas F Easton

Nature 2017 11 23;551(7678):92-94. Epub 2017 Oct 23.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/nature24284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798588PMC
November 2017

Reproductive profiles and risk of breast cancer subtypes: a multi-center case-only study.

Breast Cancer Res 2017 Nov 7;19(1):119. Epub 2017 Nov 7.

Department of Oncology, Leuven Multidisciplinary Breast Cancer, University Hospital Leuven, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1186/s13058-017-0909-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688822PMC
November 2017

Low Tumor Mitochondrial DNA Content Is Associated with Better Outcome in Breast Cancer Patients Receiving Anthracycline-Based Chemotherapy.

Clin Cancer Res 2017 Aug 18;23(16):4735-4743. Epub 2017 Apr 18.

Department of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-0032DOI Listing
August 2017

Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus.

Authors:
Hisani N Horne Charles C Chung Han Zhang Kai Yu Ludmila Prokunina-Olsson Kyriaki Michailidou Manjeet K Bolla Qin Wang Joe Dennis John L Hopper Melissa C Southey Marjanka K Schmidt Annegien Broeks Kenneth Muir Artitaya Lophatananon Peter A Fasching Matthias W Beckmann Olivia Fletcher Nichola Johnson Elinor J Sawyer Ian Tomlinson Barbara Burwinkel Frederik Marme Pascal Guénel Thérèse Truong Stig E Bojesen Henrik Flyger Javier Benitez Anna González-Neira Hoda Anton-Culver Susan L Neuhausen Hermann Brenner Volker Arndt Alfons Meindl Rita K Schmutzler Hiltrud Brauch Ute Hamann Heli Nevanlinna Sofia Khan Keitaro Matsuo Hiroji Iwata Thilo Dörk Natalia V Bogdanova Annika Lindblom Sara Margolin Arto Mannermaa Veli-Matti Kosma Georgia Chenevix-Trench Anna H Wu David Ven den Berg Ann Smeets Hui Zhao Jenny Chang-Claude Anja Rudolph Paolo Radice Monica Barile Fergus J Couch Celine Vachon Graham G Giles Roger L Milne Christopher A Haiman Loic Le Marchand Mark S Goldberg Soo H Teo Nur A M Taib Vessela Kristensen Anne-Lise Borresen-Dale Wei Zheng Martha Shrubsole Robert Winqvist Arja Jukkola-Vuorinen Irene L Andrulis Julia A Knight Peter Devilee Caroline Seynaeve Montserrat García-Closas Kamila Czene Hatef Darabi Antoinette Hollestelle John W M Martens Jingmei Li Wei Lu Xiao-Ou Shu Angela Cox Simon S Cross William Blot Qiuyin Cai Mitul Shah Craig Luccarini Caroline Baynes Patricia Harrington Daehee Kang Ji-Yeob Choi Mikael Hartman Kee Seng Chia Maria Kabisch Diana Torres Anna Jakubowska Jan Lubinski Suleeporn Sangrajrang Paul Brennan Susan Slager Drakoulis Yannoukakos Chen-Yang Shen Ming-Feng Hou Anthony Swerdlow Nick Orr Jacques Simard Per Hall Paul D P Pharoah Douglas F Easton Stephen J Chanock Alison M Dunning Jonine D Figueroa

PLoS One 2016 24;11(8):e0160316. Epub 2016 Aug 24.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996485PMC
July 2017

Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer.

Authors:
Hermela Shimelis Romy L S Mesman Catharina Von Nicolai Asa Ehlen Lucia Guidugli Charlotte Martin Fabienne M G R Calléja Huong Meeks Emily Hallberg Jamie Hinton Jenna Lilyquist Chunling Hu Cora M Aalfs Kristiina Aittomäki Irene Andrulis Hoda Anton-Culver Volker Arndt Matthias W Beckmann Javier Benitez Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Anne-Lise Borresen-Dale Hiltrud Brauch Paul Brennan Hermann Brenner Annegien Broeks Barbara Brouwers Thomas Brüning Barbara Burwinkel Jenny Chang-Claude Georgia Chenevix-Trench Ching-Yu Cheng Ji-Yeob Choi J Margriet Collée Angela Cox Simon S Cross Kamila Czene Hatef Darabi Joe Dennis Thilo Dörk Isabel Dos-Santos-Silva Alison M Dunning Peter A Fasching Jonine Figueroa Henrik Flyger Montserrat García-Closas Graham G Giles Gord Glendon Pascal Guénel Christopher A Haiman Per Hall Ute Hamann Mikael Hartman Frans B Hogervorst Antoinette Hollestelle John L Hopper Hidemi Ito Anna Jakubowska Daehee Kang Veli-Matti Kosma Vessela Kristensen Kah-Nyin Lai Diether Lambrechts Loic Le Marchand Jingmei Li Annika Lindblom Artitaya Lophatananon Jan Lubinski Eva Machackova Arto Mannermaa Sara Margolin Frederik Marme Keitaro Matsuo Hui Miao Kyriaki Michailidou Roger L Milne Kenneth Muir Susan L Neuhausen Heli Nevanlinna Janet E Olson Curtis Olswold Jan J C Oosterwijk Ana Osorio Paolo Peterlongo Julian Peto Paul D P Pharoah Katri Pylkäs Paolo Radice Muhammad Usman Rashid Valerie Rhenius Anja Rudolph Suleeporn Sangrajrang Elinor J Sawyer Marjanka K Schmidt Minouk J Schoemaker Caroline Seynaeve Mitul Shah Chen-Yang Shen Martha Shrubsole Xiao-Ou Shu Susan Slager Melissa C Southey Daniel O Stram Anthony Swerdlow Soo H Teo Ian Tomlinson Diana Torres Thérèse Truong Christi J van Asperen Lizet E van der Kolk Qin Wang Robert Winqvist Anna H Wu Jyh-Cherng Yu Wei Zheng Ying Zheng Jennifer Leary Logan Walker Lenka Foretova Florentia Fostira Kathleen B M Claes Liliana Varesco Setareh Moghadasi Douglas F Easton Amanda Spurdle Peter Devilee Harry Vrieling Alvaro N A Monteiro David E Goldgar Aura Carreira Maaike P G Vreeswijk Fergus J Couch

Cancer Res 2017 06 10;77(11):2789-2799. Epub 2017 Mar 10.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-2568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508554PMC
June 2017

Genetic modifiers of CHEK2*1100delC-associated breast cancer risk.

Genet Med 2017 05 6;19(5):599-603. Epub 2016 Oct 6.

Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/gim.2016.147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382131PMC
May 2017

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS.

Authors:
Melissa C Southey David E Goldgar Robert Winqvist Katri Pylkäs Fergus Couch Marc Tischkowitz William D Foulkes Joe Dennis Kyriaki Michailidou Elizabeth J van Rensburg Tuomas Heikkinen Heli Nevanlinna John L Hopper Thilo Dörk Kathleen Bm Claes Jorge Reis-Filho Zhi Ling Teo Paolo Radice Irene Catucci Paolo Peterlongo Helen Tsimiklis Fabrice A Odefrey James G Dowty Marjanka K Schmidt Annegien Broeks Frans B Hogervorst Senno Verhoef Jane Carpenter Christine Clarke Rodney J Scott Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Julian Peto Isabel Dos-Santos-Silva Olivia Fletcher Nichola Johnson Manjeet K Bolla Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Federik Marme Barbara Burwinkel Rongxi Yang Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Stig Bojesen Sune F Nielsen Henrik Flyger Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Hoda Anton-Culver Susan Neuhausen Argyrios Ziogas Christina A Clarke Hermann Brenner Volker Arndt Christa Stegmaier Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Taru A Muranen Kristiina Aittomäki Carl Blomqvist Natalia V Bogdanova Natalia N Antonenkova Annika Lindblom Sara Margolin Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Amanda B Spurdle kConFab Investigators Els Wauters Dominiek Smeets Benoit Beuselinck Giuseppe Floris Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Janet E Olson Celine Vachon Vernon S Pankratz Catriona McLean Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Vessela Kristensen Grethe Grenaker Alnæs Wei Zheng David J Hunter Sara Lindstrom Susan E Hankinson Peter Kraft Irene Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Arja Jukkola-Vuorinen Mervi Grip Saila Kauppila Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Antoinette Hollestelle Montserrat Garcia-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Kamila Czene Hatef Darabi Mikael Eriksson Diana M Eccles Sajjad Rafiq William J Tapper Sue M Gerty Maartje J Hooning John W M Martens J Margriet Collée Madeleine Tilanus-Linthorst Per Hall Jingmei Li Judith S Brand Keith Humphreys Angela Cox Malcolm W R Reed Craig Luccarini Caroline Baynes Alison M Dunning Ute Hamann Diana Torres Hans Ulrich Ulmer Thomas Rüdiger Anna Jakubowska Jan Lubinski Katarzyna Jaworska Katarzyna Durda Susan Slager Amanda E Toland Christine B Ambrosone Drakoulis Yannoukakos Anthony Swerdlow Alan Ashworth Nick Orr Michael Jones Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot Jacques Simard Martine Dumont Penny Soucy Rosalind Eeles Kenneth Muir Fredrik Wiklund Henrik Gronberg Johanna Schleutker Børge G Nordestgaard Maren Weischer Ruth C Travis David Neal Jenny L Donovan Freddie C Hamdy Kay-Tee Khaw Janet L Stanford William J Blot Stephen Thibodeau Daniel J Schaid Joseph L Kelley Christiane Maier Adam S Kibel Cezary Cybulski Lisa Cannon-Albright Katja Butterbach Jong Park Radka Kaneva Jyotsna Batra Manuel R Teixeira Zsofia Kote-Jarai Ali Amin Al Olama Sara Benlloch Stefan P Renner Arndt Hartmann Alexander Hein Matthias Ruebner Diether Lambrechts Els Van Nieuwenhuysen Ignace Vergote Sandrina Lambretchs Jennifer A Doherty Mary Anne Rossing Stefan Nickels Ursula Eilber Shan Wang-Gohrke Kunle Odunsi Lara E Sucheston-Campbell Grace Friel Galina Lurie Jeffrey L Killeen Lynne R Wilkens Marc T Goodman Ingo Runnebaum Peter A Hillemanns Liisa M Pelttari Ralf Butzow Francesmary Modugno Robert P Edwards Roberta B Ness Kirsten B Moysich Andreas du Bois Florian Heitz Philipp Harter Stefan Kommoss Beth Y Karlan Christine Walsh Jenny Lester Allan Jensen Susanne Krüger Kjaer Estrid Høgdall Bernard Peissel Bernardo Bonanni Loris Bernard Ellen L Goode Brooke L Fridley Robert A Vierkant Julie M Cunningham Melissa C Larson Zachary C Fogarty Kimberly R Kalli Dong Liang Karen H Lu Michelle A T Hildebrandt Xifeng Wu Douglas A Levine Fanny Dao Maria Bisogna Andrew Berchuck Edwin S Iversen Jeffrey R Marks Lucy Akushevich Daniel W Cramer Joellen Schildkraut Kathryn L Terry Elizabeth M Poole Meir Stampfer Shelley S Tworoger Elisa V Bandera Irene Orlow Sara H Olson Line Bjorge Helga B Salvesen Anne M van Altena Katja K H Aben Lambertus A Kiemeney Leon F A G Massuger Tanja Pejovic Yukie Bean Angela Brooks-Wilson Linda E Kelemen Linda S Cook Nhu D Le Bohdan Górski Jacek Gronwald Janusz Menkiszak Claus K Høgdall Lene Lundvall Lotte Nedergaard Svend Aage Engelholm Ed Dicks Jonathan Tyrer Ian Campbell Iain McNeish James Paul Nadeem Siddiqui Rosalind Glasspool Alice S Whittemore Joseph H Rothstein Valerie McGuire Weiva Sieh Hui Cai Xiao-Ou Shu Rachel T Teten Rebecca Sutphen John R McLaughlin Steven A Narod Catherine M Phelan Alvaro N Monteiro David Fenstermacher Hui-Yi Lin Jennifer B Permuth Thomas A Sellers Y Ann Chen Ya-Yu Tsai Zhihua Chen Aleksandra Gentry-Maharaj Simon A Gayther Susan J Ramus Usha Menon Anna H Wu Celeste L Pearce David Van Den Berg Malcolm C Pike Agnieszka Dansonka-Mieszkowska Joanna Plisiecka-Halasa Joanna Moes-Sosnowska Jolanta Kupryjanczyk Paul Dp Pharoah Honglin Song Ingrid Winship Georgia Chenevix-Trench Graham G Giles Sean V Tavtigian Doug F Easton Roger L Milne

J Med Genet 2016 12 5;53(12):800-811. Epub 2016 Sep 5.

Centre for Epidemiology and Biostatistics, School of Population and Global Health, The University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.1136/jmedgenet-2016-103839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5200636PMC
December 2016

rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk.

Authors:
Jingjing Liu Ivona Lončar J Margriet Collée Manjeet K Bolla Joe Dennis Kyriaki Michailidou Qin Wang Irene L Andrulis Monica Barile Matthias W Beckmann Sabine Behrens Javier Benitez Carl Blomqvist Bram Boeckx Natalia V Bogdanova Stig E Bojesen Hiltrud Brauch Paul Brennan Hermann Brenner Annegien Broeks Barbara Burwinkel Jenny Chang-Claude Shou-Tung Chen Georgia Chenevix-Trench Ching Y Cheng Ji-Yeob Choi Fergus J Couch Angela Cox Simon S Cross Katarina Cuk Kamila Czene Thilo Dörk Isabel Dos-Santos-Silva Peter A Fasching Jonine Figueroa Henrik Flyger Montserrat García-Closas Graham G Giles Gord Glendon Mark S Goldberg Anna González-Neira Pascal Guénel Christopher A Haiman Ute Hamann Steven N Hart Mikael Hartman Sigrid Hatse John L Hopper Hidemi Ito Anna Jakubowska Maria Kabisch Daehee Kang Veli-Matti Kosma Vessela N Kristensen Loic Le Marchand Eunjung Lee Jingmei Li Artitaya Lophatananon Jan Lubinski Arto Mannermaa Keitaro Matsuo Roger L Milne Susan L Neuhausen Heli Nevanlinna Nick Orr Jose I A Perez Julian Peto Thomas C Putti Katri Pylkäs Paolo Radice Suleeporn Sangrajrang Elinor J Sawyer Marjanka K Schmidt Andreas Schneeweiss Chen-Yang Shen Martha J Shrubsole Xiao-Ou Shu Jacques Simard Melissa C Southey Anthony Swerdlow Soo H Teo Daniel C Tessier Somchai Thanasitthichai Ian Tomlinson Diana Torres Thérèse Truong Chiu-Chen Tseng Celine Vachon Robert Winqvist Anna H Wu Drakoulis Yannoukakos Wei Zheng Per Hall Alison M Dunning Douglas F Easton Maartje J Hooning Ans M W van den Ouweland John W M Martens Antoinette Hollestelle

Sci Rep 2016 11 15;6:36874. Epub 2016 Nov 15.

Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/srep36874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109293PMC
November 2016

Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer.

Authors:
Jiajun Shi Yanfeng Zhang Wei Zheng Kyriaki Michailidou Maya Ghoussaini Manjeet K Bolla Qin Wang Joe Dennis Michael Lush Roger L Milne Xiao-Ou Shu Jonathan Beesley Siddhartha Kar Irene L Andrulis Hoda Anton-Culver Volker Arndt Matthias W Beckmann Zhiguo Zhao Xingyi Guo Javier Benitez Alicia Beeghly-Fadiel William Blot Natalia V Bogdanova Stig E Bojesen Hiltrud Brauch Hermann Brenner Louise Brinton Annegien Broeks Thomas Brüning Barbara Burwinkel Hui Cai Sander Canisius Jenny Chang-Claude Ji-Yeob Choi Fergus J Couch Angela Cox Simon S Cross Kamila Czene Hatef Darabi Peter Devilee Arnaud Droit Thilo Dork Peter A Fasching Olivia Fletcher Henrik Flyger Florentia Fostira Valerie Gaborieau Montserrat García-Closas Graham G Giles Pascal Guenel Christopher A Haiman Ute Hamann Mikael Hartman Hui Miao Antoinette Hollestelle John L Hopper Chia-Ni Hsiung Hidemi Ito Anna Jakubowska Nichola Johnson Diana Torres Maria Kabisch Daehee Kang Sofia Khan Julia A Knight Veli-Matti Kosma Diether Lambrechts Jingmei Li Annika Lindblom Artitaya Lophatananon Jan Lubinski Arto Mannermaa Siranoush Manoukian Loic Le Marchand Sara Margolin Frederik Marme Keitaro Matsuo Catriona McLean Alfons Meindl Kenneth Muir Susan L Neuhausen Heli Nevanlinna Silje Nord Anne-Lise Børresen-Dale Janet E Olson Nick Orr Ans M W van den Ouweland Paolo Peterlongo Thomas Choudary Putti Anja Rudolph Suleeporn Sangrajrang Elinor J Sawyer Marjanka K Schmidt Rita K Schmutzler Chen-Yang Shen Ming-Feng Hou Matha J Shrubsole Melissa C Southey Anthony Swerdlow Soo Hwang Teo Bernard Thienpont Amanda E Toland Robert A E M Tollenaar Ian Tomlinson Therese Truong Chiu-Chen Tseng Wanqing Wen Robert Winqvist Anna H Wu Cheng Har Yip Pilar M Zamora Ying Zheng Giuseppe Floris Ching-Yu Cheng Maartje J Hooning John W M Martens Caroline Seynaeve Vessela N Kristensen Per Hall Paul D P Pharoah Jacques Simard Georgia Chenevix-Trench Alison M Dunning Antonis C Antoniou Douglas F Easton Qiuyin Cai Jirong Long

Int J Cancer 2016 Sep 17;139(6):1303-1317. Epub 2016 Jun 17.

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA.

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http://dx.doi.org/10.1002/ijc.30150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110427PMC
September 2016

Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).

Authors:
Hatef Darabi Jonathan Beesley Arnaud Droit Siddhartha Kar Silje Nord Mahdi Moradi Marjaneh Penny Soucy Kyriaki Michailidou Maya Ghoussaini Hanna Fues Wahl Manjeet K Bolla Qin Wang Joe Dennis M Rosario Alonso Irene L Andrulis Hoda Anton-Culver Volker Arndt Matthias W Beckmann Javier Benitez Natalia V Bogdanova Stig E Bojesen Hiltrud Brauch Hermann Brenner Annegien Broeks Thomas Brüning Barbara Burwinkel Jenny Chang-Claude Ji-Yeob Choi Don M Conroy Fergus J Couch Angela Cox Simon S Cross Kamila Czene Peter Devilee Thilo Dörk Douglas F Easton Peter A Fasching Jonine Figueroa Olivia Fletcher Henrik Flyger Eva Galle Montserrat García-Closas Graham G Giles Mark S Goldberg Anna González-Neira Pascal Guénel Christopher A Haiman Emily Hallberg Ute Hamann Mikael Hartman Antoinette Hollestelle John L Hopper Hidemi Ito Anna Jakubowska Nichola Johnson Daehee Kang Sofia Khan Veli-Matti Kosma Mieke Kriege Vessela Kristensen Diether Lambrechts Loic Le Marchand Soo Chin Lee Annika Lindblom Artitaya Lophatananon Jan Lubinski Arto Mannermaa Siranoush Manoukian Sara Margolin Keitaro Matsuo Rebecca Mayes James McKay Alfons Meindl Roger L Milne Kenneth Muir Susan L Neuhausen Heli Nevanlinna Curtis Olswold Nick Orr Paolo Peterlongo Guillermo Pita Katri Pylkäs Anja Rudolph Suleeporn Sangrajrang Elinor J Sawyer Marjanka K Schmidt Rita K Schmutzler Caroline Seynaeve Mitul Shah Chen-Yang Shen Xiao-Ou Shu Melissa C Southey Daniel O Stram Harald Surowy Anthony Swerdlow Soo H Teo Daniel C Tessier Ian Tomlinson Diana Torres Thérèse Truong Celine M Vachon Daniel Vincent Robert Winqvist Anna H Wu Pei-Ei Wu Cheng Har Yip Wei Zheng Paul D P Pharoah Per Hall Stacey L Edwards Jacques Simard Juliet D French Georgia Chenevix-Trench Alison M Dunning

Sci Rep 2016 09 7;6:32512. Epub 2016 Sep 7.

Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/srep32512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013272PMC
September 2016

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.

Authors:
Kate Lawrenson Siddhartha Kar Karen McCue Karoline Kuchenbaeker Kyriaki Michailidou Jonathan Tyrer Jonathan Beesley Susan J Ramus Qiyuan Li Melissa K Delgado Janet M Lee Kristiina Aittomäki Irene L Andrulis Hoda Anton-Culver Volker Arndt Banu K Arun Brita Arver Elisa V Bandera Monica Barile Rosa B Barkardottir Daniel Barrowdale Matthias W Beckmann Javier Benitez Andrew Berchuck Maria Bisogna Line Bjorge Carl Blomqvist William Blot Natalia Bogdanova Anders Bojesen Stig E Bojesen Manjeet K Bolla Bernardo Bonanni Anne-Lise Børresen-Dale Hiltrud Brauch Paul Brennan Hermann Brenner Fiona Bruinsma Joan Brunet Shaik Ahmad Buhari Barbara Burwinkel Ralf Butzow Saundra S Buys Qiuyin Cai Trinidad Caldes Ian Campbell Rikki Canniotto Jenny Chang-Claude Jocelyne Chiquette Ji-Yeob Choi Kathleen B M Claes Linda S Cook Angela Cox Daniel W Cramer Simon S Cross Cezary Cybulski Kamila Czene Mary B Daly Francesca Damiola Agnieszka Dansonka-Mieszkowska Hatef Darabi Joe Dennis Peter Devilee Orland Diez Jennifer A Doherty Susan M Domchek Cecilia M Dorfling Thilo Dörk Martine Dumont Hans Ehrencrona Bent Ejlertsen Steve Ellis Christoph Engel Eunjung Lee D Gareth Evans Peter A Fasching Lidia Feliubadalo Jonine Figueroa Dieter Flesch-Janys Olivia Fletcher Henrik Flyger Lenka Foretova Florentia Fostira William D Foulkes Brooke L Fridley Eitan Friedman Debra Frost Gaetana Gambino Patricia A Ganz Judy Garber Montserrat García-Closas Aleksandra Gentry-Maharaj Maya Ghoussaini Graham G Giles Rosalind Glasspool Andrew K Godwin Mark S Goldberg David E Goldgar Anna González-Neira Ellen L Goode Marc T Goodman Mark H Greene Jacek Gronwald Pascal Guénel Christopher A Haiman Per Hall Emily Hallberg Ute Hamann Thomas V O Hansen Patricia A Harrington Mikael Hartman Norhashimah Hassan Sue Healey Florian Heitz Josef Herzog Estrid Høgdall Claus K Høgdall Frans B L Hogervorst Antoinette Hollestelle John L Hopper Peter J Hulick Tomasz Huzarski Evgeny N Imyanitov Claudine Isaacs Hidemi Ito Anna Jakubowska Ramunas Janavicius Allan Jensen Esther M John Nichola Johnson Maria Kabisch Daehee Kang Miroslav Kapuscinski Beth Y Karlan Sofia Khan Lambertus A Kiemeney Susanne Kruger Kjaer Julia A Knight Irene Konstantopoulou Veli-Matti Kosma Vessela Kristensen Jolanta Kupryjanczyk Ava Kwong Miguel de la Hoya Yael Laitman Diether Lambrechts Nhu Le Kim De Leeneer Jenny Lester Douglas A Levine Jingmei Li Annika Lindblom Jirong Long Artitaya Lophatananon Jennifer T Loud Karen Lu Jan Lubinski Arto Mannermaa Siranoush Manoukian Loic Le Marchand Sara Margolin Frederik Marme Leon F A G Massuger Keitaro Matsuo Sylvie Mazoyer Lesley McGuffog Catriona McLean Iain McNeish Alfons Meindl Usha Menon Arjen R Mensenkamp Roger L Milne Marco Montagna Kirsten B Moysich Kenneth Muir Anna Marie Mulligan Katherine L Nathanson Roberta B Ness Susan L Neuhausen Heli Nevanlinna Silje Nord Robert L Nussbaum Kunle Odunsi Kenneth Offit Edith Olah Olufunmilayo I Olopade Janet E Olson Curtis Olswold David O'Malley Irene Orlow Nick Orr Ana Osorio Sue Kyung Park Celeste L Pearce Tanja Pejovic Paolo Peterlongo Georg Pfeiler Catherine M Phelan Elizabeth M Poole Katri Pylkäs Paolo Radice Johanna Rantala Muhammad Usman Rashid Gad Rennert Valerie Rhenius Kerstin Rhiem Harvey A Risch Gus Rodriguez Mary Anne Rossing Anja Rudolph Helga B Salvesen Suleeporn Sangrajrang Elinor J Sawyer Joellen M Schildkraut Marjanka K Schmidt Rita K Schmutzler Thomas A Sellers Caroline Seynaeve Mitul Shah Chen-Yang Shen Xiao-Ou Shu Weiva Sieh Christian F Singer Olga M Sinilnikova Susan Slager Honglin Song Penny Soucy Melissa C Southey Marie Stenmark-Askmalm Dominique Stoppa-Lyonnet Christian Sutter Anthony Swerdlow Sandrine Tchatchou Manuel R Teixeira Soo H Teo Kathryn L Terry Mary Beth Terry Mads Thomassen Maria Grazia Tibiletti Laima Tihomirova Silvia Tognazzo Amanda Ewart Toland Ian Tomlinson Diana Torres Thérèse Truong Chiu-Chen Tseng Nadine Tung Shelley S Tworoger Celine Vachon Ans M W van den Ouweland Helena C van Doorn Elizabeth J van Rensburg Laura J Van't Veer Adriaan Vanderstichele Ignace Vergote Joseph Vijai Qin Wang Shan Wang-Gohrke Jeffrey N Weitzel Nicolas Wentzensen Alice S Whittemore Hans Wildiers Robert Winqvist Anna H Wu Drakoulis Yannoukakos Sook-Yee Yoon Jyh-Cherng Yu Wei Zheng Ying Zheng Kum Kum Khanna Jacques Simard Alvaro N Monteiro Juliet D French Fergus J Couch Matthew L Freedman Douglas F Easton Alison M Dunning Paul D Pharoah Stacey L Edwards Georgia Chenevix-Trench Antonis C Antoniou Simon A Gayther

Nat Commun 2016 09 7;7:12675. Epub 2016 Sep 7.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA.

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http://dx.doi.org/10.1038/ncomms12675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023955PMC
September 2016

Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers.

J Clin Oncol 2016 08 6;34(23):2750-60. Epub 2016 Jun 6.

Marjanka K. Schmidt, Frans Hogervorst, Richard van Hien, Sten Cornelissen, Annegien Broeks, and Lizet van der Kolk, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital; Muriel A. Adank, Hanne Meijers, and Quinten Waisfisz, VU University Medical Center, Amsterdam; Antoinette Hollestelle, Mieke Schutte, Maartje Hooning, and Caroline Seynaeve, Erasmus MC Cancer Institute; Ans van den Ouweland, Erasmus University Medical Center, Rotterdam; Rob A.E.M. Tollenaar, Leiden University Medical Center, Leiden, the Netherlands; Irene L. Andrulis and Julia A. Knight, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital; Irene L. Andrulis and Julia A. Knight, University of Toronto, Toronto, Ontario, Canada; Hoda Anton-Culver and Argyrios Ziogas, University of California, Irvine; Peter A. Fasching, David Geffen School of Medicine, University of California, Los Angeles; Esther M. John, Cancer Prevention Institute of California, Fremont; Esther M. John, Alice S. Whittemore, Stanford University School of Medicine, Stanford, CA; Natalia N. Antonenkova, N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus; Antonis C. Antoniou, Manjeet K. Bolla, Andrew Lee, Alison M. Dunning, Paul D.P. Pharoah, Qin Wang, and Douglas F. Easton, University of Cambridge, Cambridge; Angela Cox and Simon S. Cross, University of Sheffield, Sheffield; Olivia Fletcher, Michael Jones, and Anthony Swerdlow, The Institute of Cancer Research; Julian Peto, London School of Hygiene and Tropical Medicine; Elinor J. Sawyer, King's College London, London; Jonine Figueroa, University of Edinburgh Medical School, Edinburgh; Ian Tomlinson, University of Oxford, Oxford, United Kingdom; Volker Arndt, Hiltrud Brauch, Hermann Brenner, Barbara Burwinkel, Jenny Chang-Claude, Anja Rudolph, Harold Surowy, German Cancer Research Center; Barbara Burwinkel and Harald Surowy, University of Heidelberg, Heidelberg; Natalia V. Bogdanova, Peter Hillemanns, Tjoung-Won Park-Simon, and Thilo

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http://dx.doi.org/10.1200/JCO.2016.66.5844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019754PMC
August 2016

Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus.

Authors:
Chenjie Zeng Xingyi Guo Jirong Long Karoline B Kuchenbaecker Arnaud Droit Kyriaki Michailidou Maya Ghoussaini Siddhartha Kar Adam Freeman John L Hopper Roger L Milne Manjeet K Bolla Qin Wang Joe Dennis Simona Agata Shahana Ahmed Kristiina Aittomäki Irene L Andrulis Hoda Anton-Culver Natalia N Antonenkova Adalgeir Arason Volker Arndt Banu K Arun Brita Arver Francois Bacot Daniel Barrowdale Caroline Baynes Alicia Beeghly-Fadiel Javier Benitez Marina Bermisheva Carl Blomqvist William J Blot Natalia V Bogdanova Stig E Bojesen Bernardo Bonanni Anne-Lise Borresen-Dale Judith S Brand Hiltrud Brauch Paul Brennan Hermann Brenner Annegien Broeks Thomas Brüning Barbara Burwinkel Saundra S Buys Qiuyin Cai Trinidad Caldes Ian Campbell Jane Carpenter Jenny Chang-Claude Ji-Yeob Choi Kathleen B M Claes Christine Clarke Angela Cox Simon S Cross Kamila Czene Mary B Daly Miguel de la Hoya Kim De Leeneer Peter Devilee Orland Diez Susan M Domchek Michele Doody Cecilia M Dorfling Thilo Dörk Isabel Dos-Santos-Silva Martine Dumont Miriam Dwek Bernd Dworniczak Kathleen Egan Ursula Eilber Zakaria Einbeigi Bent Ejlertsen Steve Ellis Debra Frost Fiona Lalloo Peter A Fasching Jonine Figueroa Henrik Flyger Michael Friedlander Eitan Friedman Gaetana Gambino Yu-Tang Gao Judy Garber Montserrat García-Closas Andrea Gehrig Francesca Damiola Fabienne Lesueur Sylvie Mazoyer Dominique Stoppa-Lyonnet Graham G Giles Andrew K Godwin David E Goldgar Anna González-Neira Mark H Greene Pascal Guénel Lothar Haeberle Christopher A Haiman Emily Hallberg Ute Hamann Thomas V O Hansen Steven Hart Jaana M Hartikainen Mikael Hartman Norhashimah Hassan Sue Healey Frans B L Hogervorst Senno Verhoef Carolyn B Hendricks Peter Hillemanns Antoinette Hollestelle Peter J Hulick David J Hunter Evgeny N Imyanitov Claudine Isaacs Hidemi Ito Anna Jakubowska Ramunas Janavicius Katarzyna Jaworska-Bieniek Uffe Birk Jensen Esther M John Charles Joly Beauparlant Michael Jones Maria Kabisch Daehee Kang Beth Y Karlan Saila Kauppila Michael J Kerin Sofia Khan Elza Khusnutdinova Julia A Knight Irene Konstantopoulou Peter Kraft Ava Kwong Yael Laitman Diether Lambrechts Conxi Lazaro Loic Le Marchand Chuen Neng Lee Min Hyuk Lee Jenny Lester Jingmei Li Annelie Liljegren Annika Lindblom Artitaya Lophatananon Jan Lubinski Phuong L Mai Arto Mannermaa Siranoush Manoukian Sara Margolin Frederik Marme Keitaro Matsuo Lesley McGuffog Alfons Meindl Florence Menegaux Marco Montagna Kenneth Muir Anna Marie Mulligan Katherine L Nathanson Susan L Neuhausen Heli Nevanlinna Polly A Newcomb Silje Nord Robert L Nussbaum Kenneth Offit Edith Olah Olufunmilayo I Olopade Curtis Olswold Ana Osorio Laura Papi Tjoung-Won Park-Simon Ylva Paulsson-Karlsson Stephanie Peeters Bernard Peissel Paolo Peterlongo Julian Peto Georg Pfeiler Catherine M Phelan Nadege Presneau Paolo Radice Nazneen Rahman Susan J Ramus Muhammad Usman Rashid Gad Rennert Kerstin Rhiem Anja Rudolph Ritu Salani Suleeporn Sangrajrang Elinor J Sawyer Marjanka K Schmidt Rita K Schmutzler Minouk J Schoemaker Peter Schürmann Caroline Seynaeve Chen-Yang Shen Martha J Shrubsole Xiao-Ou Shu Alice Sigurdson Christian F Singer Susan Slager Penny Soucy Melissa Southey Doris Steinemann Anthony Swerdlow Csilla I Szabo Sandrine Tchatchou Manuel R Teixeira Soo H Teo Mary Beth Terry Daniel C Tessier Alex Teulé Mads Thomassen Laima Tihomirova Marc Tischkowitz Amanda E Toland Nadine Tung Clare Turnbull Ans M W van den Ouweland Elizabeth J van Rensburg David Ven den Berg Joseph Vijai Shan Wang-Gohrke Jeffrey N Weitzel Alice S Whittemore Robert Winqvist Tien Y Wong Anna H Wu Drakoulis Yannoukakos Jyh-Cherng Yu Paul D P Pharoah Per Hall Georgia Chenevix-Trench Alison M Dunning Jacques Simard Fergus J Couch Antonis C Antoniou Douglas F Easton Wei Zheng

Breast Cancer Res 2016 06 21;18(1):64. Epub 2016 Jun 21.

Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, 2525 West End Avenue, 8th Floor, Nashville, TN, 37203-1738, USA.

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http://dx.doi.org/10.1186/s13058-016-0718-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962376PMC
June 2016

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

Authors:
Antoinette Hollestelle Frederieke H van der Baan Andrew Berchuck Sharon E Johnatty Katja K Aben Bjarni A Agnarsson Kristiina Aittomäki Elisa Alducci Irene L Andrulis Hoda Anton-Culver Natalia N Antonenkova Antonis C Antoniou Carmel Apicella Volker Arndt Norbert Arnold Banu K Arun Brita Arver Alan Ashworth Laura Baglietto Rosemary Balleine Elisa V Bandera Daniel Barrowdale Yukie T Bean Lars Beckmann Matthias W Beckmann Javier Benitez Andreas Berger Raanan Berger Benoit Beuselinck Maria Bisogna Line Bjorge Carl Blomqvist Natalia V Bogdanova Anders Bojesen Stig E Bojesen Manjeet K Bolla Bernardo Bonanni Judith S Brand Hiltrud Brauch Hermann Brenner Louise Brinton Angela Brooks-Wilson Fiona Bruinsma Joan Brunet Thomas Brüning Agnieszka Budzilowska Clareann H Bunker Barbara Burwinkel Ralf Butzow Saundra S Buys Maria A Caligo Ian Campbell Jonathan Carter Jenny Chang-Claude Stephen J Chanock Kathleen B M Claes J Margriet Collée Linda S Cook Fergus J Couch Angela Cox Daniel Cramer Simon S Cross Julie M Cunningham Cezary Cybulski Kamila Czene Francesca Damiola Agnieszka Dansonka-Mieszkowska Hatef Darabi Miguel de la Hoya Anna deFazio Joseph Dennis Peter Devilee Ed M Dicks Orland Diez Jennifer A Doherty Susan M Domchek Cecilia M Dorfling Thilo Dörk Isabel Dos Santos Silva Andreas du Bois Martine Dumont Alison M Dunning Mercedes Duran Douglas F Easton Diana Eccles Robert P Edwards Hans Ehrencrona Bent Ejlertsen Arif B Ekici Steve D Ellis Christoph Engel Mikael Eriksson Peter A Fasching Lidia Feliubadalo Jonine Figueroa Dieter Flesch-Janys Olivia Fletcher Annette Fontaine Stefano Fortuzzi Florentia Fostira Brooke L Fridley Tara Friebel Eitan Friedman Grace Friel Debra Frost Judy Garber Montserrat García-Closas Simon A Gayther Aleksandra Gentry-Maharaj Anne-Marie Gerdes Graham G Giles Rosalind Glasspool Gord Glendon Andrew K Godwin Marc T Goodman Martin Gore Mark H Greene Mervi Grip Jacek Gronwald Daphne Gschwantler Kaulich Pascal Guénel Starr R Guzman Lothar Haeberle Christopher A Haiman Per Hall Sandra L Halverson Ute Hamann Thomas V O Hansen Philipp Harter Jaana M Hartikainen Sue Healey Alexander Hein Florian Heitz Brian E Henderson Josef Herzog Michelle A T Hildebrandt Claus K Høgdall Estrid Høgdall Frans B L Hogervorst John L Hopper Keith Humphreys Tomasz Huzarski Evgeny N Imyanitov Claudine Isaacs Anna Jakubowska Ramunas Janavicius Katarzyna Jaworska Allan Jensen Uffe Birk Jensen Nichola Johnson Arja Jukkola-Vuorinen Maria Kabisch Beth Y Karlan Vesa Kataja Noah Kauff Linda E Kelemen Michael J Kerin Lambertus A Kiemeney Susanne K Kjaer Julia A Knight Jacoba P Knol-Bout Irene Konstantopoulou Veli-Matti Kosma Camilla Krakstad Vessela Kristensen Karoline B Kuchenbaecker Jolanta Kupryjanczyk Yael Laitman Diether Lambrechts Sandrina Lambrechts Melissa C Larson Adriana Lasa Pierre Laurent-Puig Conxi Lazaro Nhu D Le Loic Le Marchand Arto Leminen Jenny Lester Douglas A Levine Jingmei Li Dong Liang Annika Lindblom Noralane Lindor Jolanta Lissowska Jirong Long Karen H Lu Jan Lubinski Lene Lundvall Galina Lurie Phuong L Mai Arto Mannermaa Sara Margolin Frederique Mariette Frederik Marme John W M Martens Leon F A G Massuger Christine Maugard Sylvie Mazoyer Lesley McGuffog Valerie McGuire Catriona McLean Iain McNeish Alfons Meindl Florence Menegaux Primitiva Menéndez Janusz Menkiszak Usha Menon Arjen R Mensenkamp Nicola Miller Roger L Milne Francesmary Modugno Marco Montagna Kirsten B Moysich Heiko Müller Anna Marie Mulligan Taru A Muranen Steven A Narod Katherine L Nathanson Roberta B Ness Susan L Neuhausen Heli Nevanlinna Patrick Neven Finn C Nielsen Sune F Nielsen Børge G Nordestgaard Robert L Nussbaum Kunle Odunsi Kenneth Offit Edith Olah Olufunmilayo I Olopade Janet E Olson Sara H Olson Jan C Oosterwijk Irene Orlow Nick Orr Sandra Orsulic Ana Osorio Laura Ottini James Paul Celeste L Pearce Inge Sokilde Pedersen Bernard Peissel Tanja Pejovic Liisa M Pelttari Jo Perkins Jenny Permuth-Wey Paolo Peterlongo Julian Peto Catherine M Phelan Kelly-Anne Phillips Marion Piedmonte Malcolm C Pike Radka Platte Joanna Plisiecka-Halasa Elizabeth M Poole Bruce Poppe Katri Pylkäs Paolo Radice Susan J Ramus Timothy R Rebbeck Malcolm W R Reed Gad Rennert Harvey A Risch Mark Robson Gustavo C Rodriguez Atocha Romero Mary Anne Rossing Joseph H Rothstein Anja Rudolph Ingo Runnebaum Ritu Salani Helga B Salvesen Elinor J Sawyer Joellen M Schildkraut Marjanka K Schmidt Rita K Schmutzler Andreas Schneeweiss Minouk J Schoemaker Michael G Schrauder Fredrick Schumacher Ira Schwaab Giulietta Scuvera Thomas A Sellers Gianluca Severi Caroline M Seynaeve Mitul Shah Martha Shrubsole Nadeem Siddiqui Weiva Sieh Jacques Simard Christian F Singer Olga M Sinilnikova Dominiek Smeets Christof Sohn Maria Soller Honglin Song Penny Soucy Melissa C Southey Christa Stegmaier Dominique Stoppa-Lyonnet Lara Sucheston Anthony Swerdlow Ingvild L Tangen Muy-Kheng Tea Manuel R Teixeira Kathryn L Terry Mary Beth Terry Mads Thomassen Pamela J Thompson Laima Tihomirova Marc Tischkowitz Amanda Ewart Toland Rob A E M Tollenaar Ian Tomlinson Diana Torres Thérèse Truong Helen Tsimiklis Nadine Tung Shelley S Tworoger Jonathan P Tyrer Celine M Vachon Laura J Van 't Veer Anne M van Altena C J Van Asperen David van den Berg Ans M W van den Ouweland Helena C van Doorn Els Van Nieuwenhuysen Elizabeth J van Rensburg Ignace Vergote Senno Verhoef Robert A Vierkant Joseph Vijai Allison F Vitonis Anna von Wachenfeldt Christine Walsh Qin Wang Shan Wang-Gohrke Barbara Wappenschmidt Maren Weischer Jeffrey N Weitzel Caroline Weltens Nicolas Wentzensen Alice S Whittemore Lynne R Wilkens Robert Winqvist Anna H Wu Xifeng Wu Hannah P Yang Daniela Zaffaroni M Pilar Zamora Wei Zheng Argyrios Ziogas Georgia Chenevix-Trench Paul D P Pharoah Matti A Rookus Maartje J Hooning Ellen L Goode

Gynecol Oncol 2016 05 2;141(2):386-401. Epub 2015 May 2.

Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1016/j.ygyno.2015.04.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630206PMC
May 2016

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

Authors:
Alison M Dunning Kyriaki Michailidou Karoline B Kuchenbaecker Deborah Thompson Juliet D French Jonathan Beesley Catherine S Healey Siddhartha Kar Karen A Pooley Elena Lopez-Knowles Ed Dicks Daniel Barrowdale Nicholas A Sinnott-Armstrong Richard C Sallari Kristine M Hillman Susanne Kaufmann Haran Sivakumaran Mahdi Moradi Marjaneh Jason S Lee Margaret Hills Monika Jarosz Suzie Drury Sander Canisius Manjeet K Bolla Joe Dennis Qin Wang John L Hopper Melissa C Southey Annegien Broeks Marjanka K Schmidt Artitaya Lophatananon Kenneth Muir Matthias W Beckmann Peter A Fasching Isabel Dos-Santos-Silva Julian Peto Elinor J Sawyer Ian Tomlinson Barbara Burwinkel Frederik Marme Pascal Guénel Thérèse Truong Stig E Bojesen Henrik Flyger Anna González-Neira Jose I A Perez Hoda Anton-Culver Lee Eunjung Volker Arndt Hermann Brenner Alfons Meindl Rita K Schmutzler Hiltrud Brauch Ute Hamann Kristiina Aittomäki Carl Blomqvist Hidemi Ito Keitaro Matsuo Natasha Bogdanova Thilo Dörk Annika Lindblom Sara Margolin Veli-Matti Kosma Arto Mannermaa Chiu-Chen Tseng Anna H Wu Diether Lambrechts Hans Wildiers Jenny Chang-Claude Anja Rudolph Paolo Peterlongo Paolo Radice Janet E Olson Graham G Giles Roger L Milne Christopher A Haiman Brian E Henderson Mark S Goldberg Soo H Teo Cheng Har Yip Silje Nord Anne-Lise Borresen-Dale Vessela Kristensen Jirong Long Wei Zheng Katri Pylkäs Robert Winqvist Irene L Andrulis Julia A Knight Peter Devilee Caroline Seynaeve Jonine Figueroa Mark E Sherman Kamila Czene Hatef Darabi Antoinette Hollestelle Ans M W van den Ouweland Keith Humphreys Yu-Tang Gao Xiao-Ou Shu Angela Cox Simon S Cross William Blot Qiuyin Cai Maya Ghoussaini Barbara J Perkins Mitul Shah Ji-Yeob Choi Daehee Kang Soo Chin Lee Mikael Hartman Maria Kabisch Diana Torres Anna Jakubowska Jan Lubinski Paul Brennan Suleeporn Sangrajrang Christine B Ambrosone Amanda E Toland Chen-Yang Shen Pei-Ei Wu Nick Orr Anthony Swerdlow Lesley McGuffog Sue Healey Andrew Lee Miroslav Kapuscinski Esther M John Mary Beth Terry Mary B Daly David E Goldgar Saundra S Buys Ramunas Janavicius Laima Tihomirova Nadine Tung Cecilia M Dorfling Elizabeth J van Rensburg Susan L Neuhausen Bent Ejlertsen Thomas V O Hansen Ana Osorio Javier Benitez Rachel Rando Jeffrey N Weitzel Bernardo Bonanni Bernard Peissel Siranoush Manoukian Laura Papi Laura Ottini Irene Konstantopoulou Paraskevi Apostolou Judy Garber Muhammad Usman Rashid Debra Frost Louise Izatt Steve Ellis Andrew K Godwin Norbert Arnold Dieter Niederacher Kerstin Rhiem Nadja Bogdanova-Markov Charlotte Sagne Dominique Stoppa-Lyonnet Francesca Damiola Olga M Sinilnikova Sylvie Mazoyer Claudine Isaacs Kathleen B M Claes Kim De Leeneer Miguel de la Hoya Trinidad Caldes Heli Nevanlinna Sofia Khan Arjen R Mensenkamp Maartje J Hooning Matti A Rookus Ava Kwong Edith Olah Orland Diez Joan Brunet Miquel Angel Pujana Jacek Gronwald Tomasz Huzarski Rosa B Barkardottir Rachel Laframboise Penny Soucy Marco Montagna Simona Agata Manuel R Teixeira Sue Kyung Park Noralane Lindor Fergus J Couch Marc Tischkowitz Lenka Foretova Joseph Vijai Kenneth Offit Christian F Singer Christine Rappaport Catherine M Phelan Mark H Greene Phuong L Mai Gad Rennert Evgeny N Imyanitov Peter J Hulick Kelly-Anne Phillips Marion Piedmonte Anna Marie Mulligan Gord Glendon Anders Bojesen Mads Thomassen Maria A Caligo Sook-Yee Yoon Eitan Friedman Yael Laitman Ake Borg Anna von Wachenfeldt Hans Ehrencrona Johanna Rantala Olufunmilayo I Olopade Patricia A Ganz Robert L Nussbaum Simon A Gayther Katherine L Nathanson Susan M Domchek Banu K Arun Gillian Mitchell Beth Y Karlan Jenny Lester Gertraud Maskarinec Christy Woolcott Christopher Scott Jennifer Stone Carmel Apicella Rulla Tamimi Robert Luben Kay-Tee Khaw Åslaug Helland Vilde Haakensen Mitch Dowsett Paul D P Pharoah Jacques Simard Per Hall Montserrat García-Closas Celine Vachon Georgia Chenevix-Trench Antonis C Antoniou Douglas F Easton Stacey L Edwards

Nat Genet 2016 Apr 29;48(4):374-86. Epub 2016 Feb 29.

Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/ng.3521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938803PMC
April 2016

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer.

Authors:
Fergus J Couch Karoline B Kuchenbaecker Kyriaki Michailidou Gustavo A Mendoza-Fandino Silje Nord Janna Lilyquist Curtis Olswold Emily Hallberg Simona Agata Habibul Ahsan Kristiina Aittomäki Christine Ambrosone Irene L Andrulis Hoda Anton-Culver Volker Arndt Banu K Arun Brita Arver Monica Barile Rosa B Barkardottir Daniel Barrowdale Lars Beckmann Matthias W Beckmann Javier Benitez Stephanie V Blank Carl Blomqvist Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Bernardo Bonanni Hiltrud Brauch Hermann Brenner Barbara Burwinkel Saundra S Buys Trinidad Caldes Maria A Caligo Federico Canzian Jane Carpenter Jenny Chang-Claude Stephen J Chanock Wendy K Chung Kathleen B M Claes Angela Cox Simon S Cross Julie M Cunningham Kamila Czene Mary B Daly Francesca Damiola Hatef Darabi Miguel de la Hoya Peter Devilee Orland Diez Yuan C Ding Riccardo Dolcetti Susan M Domchek Cecilia M Dorfling Isabel Dos-Santos-Silva Martine Dumont Alison M Dunning Diana M Eccles Hans Ehrencrona Arif B Ekici Heather Eliassen Steve Ellis Peter A Fasching Jonine Figueroa Dieter Flesch-Janys Asta Försti Florentia Fostira William D Foulkes Tara Friebel Eitan Friedman Debra Frost Marike Gabrielson Marilie D Gammon Patricia A Ganz Susan M Gapstur Judy Garber Mia M Gaudet Simon A Gayther Anne-Marie Gerdes Maya Ghoussaini Graham G Giles Gord Glendon Andrew K Godwin Mark S Goldberg David E Goldgar Anna González-Neira Mark H Greene Jacek Gronwald Pascal Guénel Marc Gunter Lothar Haeberle Christopher A Haiman Ute Hamann Thomas V O Hansen Steven Hart Sue Healey Tuomas Heikkinen Brian E Henderson Josef Herzog Frans B L Hogervorst Antoinette Hollestelle Maartje J Hooning Robert N Hoover John L Hopper Keith Humphreys David J Hunter Tomasz Huzarski Evgeny N Imyanitov Claudine Isaacs Anna Jakubowska Paul James Ramunas Janavicius Uffe Birk Jensen Esther M John Michael Jones Maria Kabisch Siddhartha Kar Beth Y Karlan Sofia Khan Kay-Tee Khaw Muhammad G Kibriya Julia A Knight Yon-Dschun Ko Irene Konstantopoulou Veli-Matti Kosma Vessela Kristensen Ava Kwong Yael Laitman Diether Lambrechts Conxi Lazaro Eunjung Lee Loic Le Marchand Jenny Lester Annika Lindblom Noralane Lindor Sara Lindstrom Jianjun Liu Jirong Long Jan Lubinski Phuong L Mai Enes Makalic Kathleen E Malone Arto Mannermaa Siranoush Manoukian Sara Margolin Frederik Marme John W M Martens Lesley McGuffog Alfons Meindl Austin Miller Roger L Milne Penelope Miron Marco Montagna Sylvie Mazoyer Anna M Mulligan Taru A Muranen Katherine L Nathanson Susan L Neuhausen Heli Nevanlinna Børge G Nordestgaard Robert L Nussbaum Kenneth Offit Edith Olah Olufunmilayo I Olopade Janet E Olson Ana Osorio Sue K Park Petra H Peeters Bernard Peissel Paolo Peterlongo Julian Peto Catherine M Phelan Robert Pilarski Bruce Poppe Katri Pylkäs Paolo Radice Nazneen Rahman Johanna Rantala Christine Rappaport Gad Rennert Andrea Richardson Mark Robson Isabelle Romieu Anja Rudolph Emiel J Rutgers Maria-Jose Sanchez Regina M Santella Elinor J Sawyer Daniel F Schmidt Marjanka K Schmidt Rita K Schmutzler Fredrick Schumacher Rodney Scott Leigha Senter Priyanka Sharma Jacques Simard Christian F Singer Olga M Sinilnikova Penny Soucy Melissa Southey Doris Steinemann Marie Stenmark-Askmalm Dominique Stoppa-Lyonnet Anthony Swerdlow Csilla I Szabo Rulla Tamimi William Tapper Manuel R Teixeira Soo-Hwang Teo Mary B Terry Mads Thomassen Deborah Thompson Laima Tihomirova Amanda E Toland Robert A E M Tollenaar Ian Tomlinson Thérèse Truong Helen Tsimiklis Alex Teulé Rosario Tumino Nadine Tung Clare Turnbull Giski Ursin Carolien H M van Deurzen Elizabeth J van Rensburg Raymonda Varon-Mateeva Zhaoming Wang Shan Wang-Gohrke Elisabete Weiderpass Jeffrey N Weitzel Alice Whittemore Hans Wildiers Robert Winqvist Xiaohong R Yang Drakoulis Yannoukakos Song Yao M Pilar Zamora Wei Zheng Per Hall Peter Kraft Celine Vachon Susan Slager Georgia Chenevix-Trench Paul D P Pharoah Alvaro A N Monteiro Montserrat García-Closas Douglas F Easton Antonis C Antoniou

Nat Commun 2016 04 27;7:11375. Epub 2016 Apr 27.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.

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April 2016

Genetic predisposition to ductal carcinoma in situ of the breast.

Authors:
Christos Petridis Mark N Brook Vandna Shah Kelly Kohut Patricia Gorman Michele Caneppele Dina Levi Efterpi Papouli Nick Orr Angela Cox Simon S Cross Isabel Dos-Santos-Silva Julian Peto Anthony Swerdlow Minouk J Schoemaker Manjeet K Bolla Qin Wang Joe Dennis Kyriaki Michailidou Javier Benitez Anna González-Neira Daniel C Tessier Daniel Vincent Jingmei Li Jonine Figueroa Vessela Kristensen Anne-Lise Borresen-Dale Penny Soucy Jacques Simard Roger L Milne Graham G Giles Sara Margolin Annika Lindblom Thomas Brüning Hiltrud Brauch Melissa C Southey John L Hopper Thilo Dörk Natalia V Bogdanova Maria Kabisch Ute Hamann Rita K Schmutzler Alfons Meindl Hermann Brenner Volker Arndt Robert Winqvist Katri Pylkäs Peter A Fasching Matthias W Beckmann Jan Lubinski Anna Jakubowska Anna Marie Mulligan Irene L Andrulis Rob A E M Tollenaar Peter Devilee Loic Le Marchand Christopher A Haiman Arto Mannermaa Veli-Matti Kosma Paolo Radice Paolo Peterlongo Frederik Marme Barbara Burwinkel Carolien H M van Deurzen Antoinette Hollestelle Nicola Miller Michael J Kerin Diether Lambrechts Giuseppe Floris Jelle Wesseling Henrik Flyger Stig E Bojesen Song Yao Christine B Ambrosone Georgia Chenevix-Trench Thérèse Truong Pascal Guénel Anja Rudolph Jenny Chang-Claude Heli Nevanlinna Carl Blomqvist Kamila Czene Judith S Brand Janet E Olson Fergus J Couch Alison M Dunning Per Hall Douglas F Easton Paul D P Pharoah Sarah E Pinder Marjanka K Schmidt Ian Tomlinson Rebecca Roylance Montserrat García-Closas Elinor J Sawyer

Breast Cancer Res 2016 Feb 17;18(1):22. Epub 2016 Feb 17.

Research Oncology, Guy's Hospital, King's College London, London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756509PMC
February 2016

Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk.

Authors:
Xingyi Guo Jirong Long Chenjie Zeng Kyriaki Michailidou Maya Ghoussaini Manjeet K Bolla Qin Wang Roger L Milne Xiao-Ou Shu Qiuyin Cai Jonathan Beesley Siddhartha P Kar Irene L Andrulis Hoda Anton-Culver Volker Arndt Matthias W Beckmann Alicia Beeghly-Fadiel Javier Benitez William Blot Natalia Bogdanova Stig E Bojesen Hiltrud Brauch Hermann Brenner Louise Brinton Annegien Broeks Thomas Brüning Barbara Burwinkel Hui Cai Sander Canisius Jenny Chang-Claude Ji-Yeob Choi Fergus J Couch Angela Cox Simon S Cross Kamila Czene Hatef Darabi Peter Devilee Arnaud Droit Thilo Dörk Peter A Fasching Olivia Fletcher Henrik Flyger Florentia Fostira Valerie Gaborieau Montserrat García-Closas Graham G Giles Mervi Grip Pascal Guénel Christopher A Haiman Ute Hamann Mikael Hartman Antoinette Hollestelle John L Hopper Chia-Ni Hsiung Hidemi Ito Anna Jakubowska Nichola Johnson Maria Kabisch Daehee Kang Sofia Khan Julia A Knight Veli-Matti Kosma Diether Lambrechts Loic Le Marchand Jingmei Li Annika Lindblom Artitaya Lophatananon Jan Lubinski Arto Mannermaa Siranoush Manoukian Sara Margolin Frederik Marme Keitaro Matsuo Catriona A McLean Alfons Meindl Kenneth Muir Susan L Neuhausen Heli Nevanlinna Silje Nord Janet E Olson Nick Orr Paolo Peterlongo Thomas Choudary Putti Anja Rudolph Suleeporn Sangrajrang Elinor J Sawyer Marjanka K Schmidt Rita K Schmutzler Chen-Yang Shen Jiajun Shi Martha J Shrubsole Melissa C Southey Anthony Swerdlow Soo Hwang Teo Bernard Thienpont Amanda Ewart Toland Robert A E M Tollenaar Ian P M Tomlinson Thérèse Truong Chiu-Chen Tseng Ans van den Ouweland Wanqing Wen Robert Winqvist Anna Wu Cheng Har Yip M Pilar Zamora Ying Zheng Per Hall Paul D P Pharoah Jacques Simard Georgia Chenevix-Trench Alison M Dunning Douglas F Easton Wei Zheng

Cancer Epidemiol Biomarkers Prev 2015 Nov 9;24(11):1680-91. Epub 2015 Sep 9.

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633342PMC
November 2015

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.

Authors:
Nick Orr Frank Dudbridge Nicola Dryden Sarah Maguire Daniela Novo Eleni Perrakis Nichola Johnson Maya Ghoussaini John L Hopper Melissa C Southey Carmel Apicella Jennifer Stone Marjanka K Schmidt Annegien Broeks Laura J Van't Veer Frans B Hogervorst Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Lorna Gibson Zoe Aitken Helen Warren Elinor Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Barbara Burwinkel Frederik Marme Andreas Schneeweiss Chistof Sohn Pascal Guénel Thérèse Truong Emilie Cordina-Duverger Marie Sanchez Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Javier Benitez Maria Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Hoda Anton-Culver Susan L Neuhausen Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Ute Hamann Hiltrud Brauch Christina Justenhoven Thomas Brüning Yon-Dschun Ko Heli Nevanlinna Kristiina Aittomäki Carl Blomqvist Sofia Khan Natalia Bogdanova Thilo Dörk Annika Lindblom Sara Margolin Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Georgia Chenevix-Trench Jonathan Beesley Diether Lambrechts Matthieu Moisse Guiseppe Floris Benoit Beuselinck Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Paolo Radice Paolo Peterlongo Bernard Peissel Valeria Pensotti Fergus J Couch Janet E Olson Seth Slettedahl Celine Vachon Graham G Giles Roger L Milne Catriona McLean Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Jacques Simard Mark S Goldberg France Labrèche Martine Dumont Vessela Kristensen Grethe Grenaker Alnæs Silje Nord Anne-Lise Borresen-Dale Wei Zheng Sandra Deming-Halverson Martha Shrubsole Jirong Long Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Peter Devilee Robertus A E M Tollenaar Caroline M Seynaeve Christi J Van Asperen Montserrat Garcia-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Kamila Czene Hatef Darabi Mikael Eriksson Daniel Klevebring Maartje J Hooning Antoinette Hollestelle Carolien H M van Deurzen Mieke Kriege Per Hall Jingmei Li Jianjun Liu Keith Humphreys Angela Cox Simon S Cross Malcolm W R Reed Paul D P Pharoah Alison M Dunning Mitul Shah Barbara J Perkins Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Alan Ashworth Anthony Swerdlow Michael Jones Minouk J Schoemaker Alfons Meindl Rita K Schmutzler Curtis Olswold Susan Slager Amanda E Toland Drakoulis Yannoukakos Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Keitaro Matsuo Hidema Ito Hiroji Iwata Junko Ishiguro Anna H Wu Chiu-Chen Tseng David Van Den Berg Daniel O Stram Soo Hwang Teo Cheng Har Yip Peter Kang Mohammad Kamran Ikram Xiao-Ou Shu Wei Lu Yu-Tang Gao Hui Cai Daehee Kang Ji-Yeob Choi Sue K Park Dong-Young Noh Mikael Hartman Hui Miao Wei Yen Lim Soo Chin Lee Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James Mckay Pei-Ei Wu Ming-Feng Hou Jyh-Cherng Yu Chen-Yang Shen William Blot Qiuyin Cai Lisa B Signorello Craig Luccarini Caroline Bayes Shahana Ahmed Mel Maranian Catherine S Healey Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot David J Hunter Sara Lindstrom Joe Dennis Kyriaki Michailidou Manjeet K Bolla Douglas F Easton Isabel dos Santos Silva Olivia Fletcher Julian Peto

Hum Mol Genet 2015 May 4;24(10):2966-84. Epub 2015 Feb 4.

Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.

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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddv035
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406292PMC
May 2015

Prediction of breast cancer risk based on profiling with common genetic variants.

Authors:
Nasim Mavaddat Paul D P Pharoah Kyriaki Michailidou Jonathan Tyrer Mark N Brook Manjeet K Bolla Qin Wang Joe Dennis Alison M Dunning Mitul Shah Robert Luben Judith Brown Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Kamila Czene Hatef Darabi Mikael Eriksson Julian Peto Isabel Dos-Santos-Silva Frank Dudbridge Nichola Johnson Marjanka K Schmidt Annegien Broeks Senno Verhoef Emiel J Rutgers Anthony Swerdlow Alan Ashworth Nick Orr Minouk J Schoemaker Jonine Figueroa Stephen J Chanock Louise Brinton Jolanta Lissowska Fergus J Couch Janet E Olson Celine Vachon Vernon S Pankratz Diether Lambrechts Hans Wildiers Chantal Van Ongeval Erik van Limbergen Vessela Kristensen Grethe Grenaker Alnæs Silje Nord Anne-Lise Borresen-Dale Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Barbara Burwinkel Frederik Marme Andreas Schneeweiss Christof Sohn Amy Trentham-Dietz Polly Newcomb Linda Titus Kathleen M Egan David J Hunter Sara Lindstrom Rulla M Tamimi Peter Kraft Nazneen Rahman Clare Turnbull Anthony Renwick Sheila Seal Jingmei Li Jianjun Liu Keith Humphreys Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Natalia V Bogdanova Natalia N Antonenkova Thilo Dörk Hoda Anton-Culver Susan L Neuhausen Argyrios Ziogas Leslie Bernstein Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J van Asperen Angela Cox Simon S Cross Malcolm W R Reed Elza Khusnutdinova Marina Bermisheva Darya Prokofyeva Zalina Takhirova Alfons Meindl Rita K Schmutzler Christian Sutter Rongxi Yang Peter Schürmann Michael Bremer Hans Christiansen Tjoung-Won Park-Simon Peter Hillemanns Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Paolo Radice Paolo Peterlongo Siranoush Manoukian Valeria Pensotti John L Hopper Helen Tsimiklis Carmel Apicella Melissa C Southey Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Alice J Sigurdson Michele M Doody Ute Hamann Diana Torres Hans-Ulrich Ulmer Asta Försti Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Georgia Chenevix-Trench Rosemary Balleine Graham G Giles Roger L Milne Catriona McLean Annika Lindblom Sara Margolin Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Ursula Eilber Shan Wang-Gohrke Maartje J Hooning Antoinette Hollestelle Ans M W van den Ouweland Linetta B Koppert Jane Carpenter Christine Clarke Rodney Scott Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Hermann Brenner Volker Arndt Christa Stegmaier Aida Karina Dieffenbach Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Kenneth Offit Joseph Vijai Mark Robson Rohini Rau-Murthy Miriam Dwek Ruth Swann Katherine Annie Perkins Mark S Goldberg France Labrèche Martine Dumont Diana M Eccles William J Tapper Sajjad Rafiq Esther M John Alice S Whittemore Susan Slager Drakoulis Yannoukakos Amanda E Toland Song Yao Wei Zheng Sandra L Halverson Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot Craig Luccarini Caroline Baynes Shahana Ahmed Mel Maranian Catherine S Healey Jacques Simard Per Hall Douglas F Easton Montserrat Garcia-Closas

J Natl Cancer Inst 2015 May 8;107(5). Epub 2015 Apr 8.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK (NM, PDPP, KM, MKB, QW, JD, RL, JBr, DFE); Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK (PDPP, JT, AMD, MS, CL, CB, SA, MM, CSH, DFE); Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK (MNB, ASw, MJS); Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark (SEB, BGN, SFN); Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Herlev, Denmark (SEB, BGN, SFN); Faculty of Health and Medical Sciences, Copenhagen University Hospital, Copenhagen, Herlev, Denmark (SEB, BGN); Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Herlev, Denmark (HF); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (KC, HD, ME, KH, PHa); Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK (JP, IdSS, FD); Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK (NJ, AA, NO, MGC); Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, the Netherlands (MKS, AB, SV, EJR); Division of Breast Cancer Research, Institute of Cancer Research, London, UK (ASw); Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD (JF, SJC, LB, ASi, MD); Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland (JLis); Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN (FJC); Department of Health Sciences Research, Mayo Clinic, Rochester, MN (JEO, CV, VSP, SS); Vesalius Research Center, VIB, Leuven, Belgium (DL); Laboratory for Translational Genetics, Department of Oncology, University of

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754625PMC
May 2015

Identification of novel genetic markers of breast cancer survival.

Authors:
Qi Guo Marjanka K Schmidt Peter Kraft Sander Canisius Constance Chen Sofia Khan Jonathan Tyrer Manjeet K Bolla Qin Wang Joe Dennis Kyriaki Michailidou Michael Lush Siddhartha Kar Jonathan Beesley Alison M Dunning Mitul Shah Kamila Czene Hatef Darabi Mikael Eriksson Diether Lambrechts Caroline Weltens Karin Leunen Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Carl Blomqvist Kristiina Aittomäki Rainer Fagerholm Taru A Muranen Fergus J Couch Janet E Olson Celine Vachon Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Annegien Broeks Frans B Hogervorst Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand John L Hopper Helen Tsimiklis Carmel Apicella Melissa C Southey Angela Cox Simon S Cross Malcolm W R Reed Graham G Giles Roger L Milne Catriona McLean Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Maartje J Hooning Antoinette Hollestelle John W M Martens Ans M W van den Ouweland Federik Marme Andreas Schneeweiss Rongxi Yang Barbara Burwinkel Jonine Figueroa Stephen J Chanock Jolanta Lissowska Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Hermann Brenner Aida Karina Dieffenbach Volker Arndt Bernd Holleczek Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Jingmei Li Judith S Brand Keith Humphreys Peter Devilee Rob A E M Tollenaar Caroline Seynaeve Paolo Radice Paolo Peterlongo Bernardo Bonanni Paolo Mariani Peter A Fasching Matthias W Beckmann Alexander Hein Arif B Ekici Georgia Chenevix-Trench Rosemary Balleine Kelly-Anne Phillips Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Ute Hamann Maria Kabisch Hans Ulrich Ulmer Thomas Rüdiger Sara Margolin Vessela Kristensen Silje Nord D Gareth Evans Jean E Abraham Helena M Earl Louise Hiller Janet A Dunn Sarah Bowden Christine Berg Daniele Campa W Ryan Diver Susan M Gapstur Mia M Gaudet Susan E Hankinson Robert N Hoover Anika Hüsing Rudolf Kaaks Mitchell J Machiela Walter Willett Myrto Barrdahl Federico Canzian Suet-Feung Chin Carlos Caldas David J Hunter Sara Lindstrom Montserrat García-Closas Per Hall Douglas F Easton Diana M Eccles Nazneen Rahman Heli Nevanlinna Paul D P Pharoah

J Natl Cancer Inst 2015 May 18;107(5). Epub 2015 Apr 18.

Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, UK (QG, JT, AMD, MS, JEA, DFE, PDPP); Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, the Netherlands (MKS, SC, AB, FBH); Department of Epidemiology, Harvard School of Public Health, Boston, MA (PK, SH, DJH, SL); Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard School of Public Health, Boston, MA (PK, CCh, DJH, SL); Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland (SK, RF, TAM, HN); Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK (MKB, QW, JD, KM, ML, SK, DFE, PDPP); Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia (JBee, GCT); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden (KC, HD, ME, JiL, JBr, KH, PH); Laboratory for Translational Genetics, Department of Oncology, University of Leuven, Leuven, Belgium (DL); Vesalius Research Center, VIB, Leuven, Belgium (DL); Oncology Department, University Hospital Gasthuisberg, Leuven, Belgium (CW, KL); Copenhagen General Population Study, Herlev Hospital, Copenhagen, Denmark (SEB, BGN, SFN); Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Denmark (SEB, BGN, SFN); Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark (SEB, BGN); Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Denmark (HF); Division of Cancer Epidemiology, German Cancer Research Center (Deutsches Krebsforschungszentrum), Heidelberg, Germany (JCC, AR, PS, DC, AHü, RK, MB); Department of Cancer Epidemiology/Clinical Cancer Registry and Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg, Germany (DFJ); Department of Oncology

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555642PMC
May 2015

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.

Authors:
Kyriaki Michailidou Jonathan Beesley Sara Lindstrom Sander Canisius Joe Dennis Michael J Lush Mel J Maranian Manjeet K Bolla Qin Wang Mitul Shah Barbara J Perkins Kamila Czene Mikael Eriksson Hatef Darabi Judith S Brand Stig E Bojesen Børge G Nordestgaard Henrik Flyger Sune F Nielsen Nazneen Rahman Clare Turnbull Olivia Fletcher Julian Peto Lorna Gibson Isabel dos-Santos-Silva Jenny Chang-Claude Dieter Flesch-Janys Anja Rudolph Ursula Eilber Sabine Behrens Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Sofia Khan Kirsimari Aaltonen Habibul Ahsan Muhammad G Kibriya Alice S Whittemore Esther M John Kathleen E Malone Marilie D Gammon Regina M Santella Giske Ursin Enes Makalic Daniel F Schmidt Graham Casey David J Hunter Susan M Gapstur Mia M Gaudet W Ryan Diver Christopher A Haiman Fredrick Schumacher Brian E Henderson Loic Le Marchand Christine D Berg Stephen J Chanock Jonine Figueroa Robert N Hoover Diether Lambrechts Patrick Neven Hans Wildiers Erik van Limbergen Marjanka K Schmidt Annegien Broeks Senno Verhoef Sten Cornelissen Fergus J Couch Janet E Olson Emily Hallberg Celine Vachon Quinten Waisfisz Hanne Meijers-Heijboer Muriel A Adank Rob B van der Luijt Jingmei Li Jianjun Liu Keith Humphreys Daehee Kang Ji-Yeob Choi Sue K Park Keun-Young Yoo Keitaro Matsuo Hidemi Ito Hiroji Iwata Kazuo Tajima Pascal Guénel Thérèse Truong Claire Mulot Marie Sanchez Barbara Burwinkel Frederik Marme Harald Surowy Christof Sohn Anna H Wu Chiu-chen Tseng David Van Den Berg Daniel O Stram Anna González-Neira Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Xiao-Ou Shu Wei Lu Yu-Tang Gao Hui Cai Angela Cox Simon S Cross Malcolm W R Reed Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Annika Lindblom Sara Margolin Soo Hwang Teo Cheng Har Yip Nur Aishah Mohd Taib Gie-Hooi Tan Maartje J Hooning Antoinette Hollestelle John W M Martens J Margriet Collée William Blot Lisa B Signorello Qiuyin Cai John L Hopper Melissa C Southey Helen Tsimiklis Carmel Apicella Chen-Yang Shen Chia-Ni Hsiung Pei-Ei Wu Ming-Feng Hou Vessela N Kristensen Silje Nord Grethe I Grenaker Alnaes Graham G Giles Roger L Milne Catriona McLean Federico Canzian Dimitrios Trichopoulos Petra Peeters Eiliv Lund Malin Sund Kay-Tee Khaw Marc J Gunter Domenico Palli Lotte Maxild Mortensen Laure Dossus Jose-Maria Huerta Alfons Meindl Rita K Schmutzler Christian Sutter Rongxi Yang Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Mikael Hartman Hui Miao Kee Seng Chia Ching Wan Chan Peter A Fasching Alexander Hein Matthias W Beckmann Lothar Haeberle Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Alan Ashworth Nick Orr Minouk J Schoemaker Anthony J Swerdlow Louise Brinton Montserrat Garcia-Closas Wei Zheng Sandra L Halverson Martha Shrubsole Jirong Long Mark S Goldberg France Labrèche Martine Dumont Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Hiltrud Brauch Ute Hamann Thomas Brüning Paolo Radice Paolo Peterlongo Siranoush Manoukian Loris Bernard Natalia V Bogdanova Thilo Dörk Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Anna Jakubowska Jan Lubinski Katarzyna Jaworska Tomasz Huzarski Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James McKay Susan Slager Amanda E Toland Christine B Ambrosone Drakoulis Yannoukakos Maria Kabisch Diana Torres Susan L Neuhausen Hoda Anton-Culver Craig Luccarini Caroline Baynes Shahana Ahmed Catherine S Healey Daniel C Tessier Daniel Vincent Francois Bacot Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Jacques Simard Paul P D P Pharoah Peter Kraft Alison M Dunning Georgia Chenevix-Trench Per Hall Douglas F Easton

Nat Genet 2015 Apr 9;47(4):373-80. Epub 2015 Mar 9.

1] Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. [2] Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.

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April 2015

Common germline polymorphisms associated with breast cancer-specific survival.

Authors:
Ailith Pirie Qi Guo Peter Kraft Sander Canisius Diana M Eccles Nazneen Rahman Heli Nevanlinna Constance Chen Sofia Khan Jonathan Tyrer Manjeet K Bolla Qin Wang Joe Dennis Kyriaki Michailidou Michael Lush Alison M Dunning Mitul Shah Kamila Czene Hatef Darabi Mikael Eriksson Dieter Lambrechts Caroline Weltens Karin Leunen Chantal van Ongeval Børge G Nordestgaard Sune F Nielsen Henrik Flyger Anja Rudolph Petra Seibold Dieter Flesch-Janys Carl Blomqvist Kristiina Aittomäki Rainer Fagerholm Taru A Muranen Janet E Olsen Emily Hallberg Celine Vachon Julia A Knight Gord Glendon Anna Marie Mulligan Annegien Broeks Sten Cornelissen Christopher A Haiman Brian E Henderson Frederick Schumacher Loic Le Marchand John L Hopper Helen Tsimiklis Carmel Apicella Melissa C Southey Simon S Cross Malcolm Wr Reed Graham G Giles Roger L Milne Catriona McLean Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Maartje J Hooning Antoinette Hollestelle John Wm Martens Ans Mw van den Ouweland Federick Marme Andreas Schneeweiss Rongxi Yang Barbara Burwinkel Jonine Figueroa Stephen J Chanock Jolanta Lissowska Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Hermann Brenner Katja Butterbach Bernd Holleczek Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Jingmei Li Judith S Brand Keith Humphreys Peter Devilee Robert Aem Tollenaar Caroline Seynaeve Paolo Radice Paolo Peterlongo Siranoush Manoukian Filomena Ficarazzi Matthias W Beckmann Alexander Hein Arif B Ekici Rosemary Balleine Kelly-Anne Phillips Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Anna Jakubowska Jan Lubinski Jacek Gronwald Katarzyna Durda Ute Hamann Maria Kabisch Hans Ulrich Ulmer Thomas Rüdiger Sara Margolin Vessela Kristensen Siljie Nord D Gareth Evans Jean Abraham Helena Earl Christopher J Poole Louise Hiller Janet A Dunn Sarah Bowden Rose Yang Daniele Campa W Ryan Diver Susan M Gapstur Mia M Gaudet Susan Hankinson Robert N Hoover Anika Hüsing Rudolf Kaaks Mitchell J Machiela Walter Willett Myrto Barrdahl Federico Canzian Suet-Feung Chin Carlos Caldas David J Hunter Sara Lindstrom Montserrat Garcia-Closas Fergus J Couch Georgia Chenevix-Trench Arto Mannermaa Irene L Andrulis Per Hall Jenny Chang-Claude Douglas F Easton Stig E Bojesen Angela Cox Peter A Fasching Paul Dp Pharoah Marjanka K Schmidt

Breast Cancer Res 2015 Apr 22;17:58. Epub 2015 Apr 22.

Netherlands Cancer Institute, Antoni Van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484708PMC
April 2015

Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer.

Authors:
Maria Kabisch Justo Lorenzo Bermejo Thomas Dünnebier Shibo Ying Kyriaki Michailidou Manjeet K Bolla Qin Wang Joe Dennis Mitul Shah Barbara J Perkins Kamila Czene Hatef Darabi Mikael Eriksson Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Diether Lambrechts Patrick Neven Stephanie Peeters Caroline Weltens Fergus J Couch Janet E Olson Xianshu Wang Kristen Purrington Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Julian Peto Isabel dos-Santos-Silva Nichola Johnson Olivia Fletcher Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Marjanka K Schmidt Annegien Broeks Sten Cornelissen Frans B L Hogervorst Jingmei Li Judith S Brand Keith Humphreys Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Barbara Burwinkel Frederik Marmé Rongxi Yang Peter Bugert Anna González-Neira Javier Benitez M Pilar Zamora Jose I Arias Perez Angela Cox Simon S Cross Malcolm W R Reed Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Christopher A Haiman Fredrick Schumacher Brian E Henderson Loic Le Marchand Annika Lindblom Sara Margolin Maartje J Hooning Antoinette Hollestelle Mieke Kriege Linetta B Koppert John L Hopper Melissa C Southey Helen Tsimiklis Carmel Apicella Seth Slettedahl Amanda E Toland Celine Vachon Drakoulis Yannoukakos Graham G Giles Roger L Milne Catriona McLean Peter A Fasching Matthias Ruebner Arif B Ekici Matthias W Beckmann Hermann Brenner Aida K Dieffenbach Volker Arndt Christa Stegmaier Alan Ashworth Nicholas Orr Minouk J Schoemaker Anthony Swerdlow Montserrat García-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Mark S Goldberg France Labrèche Martine Dumont Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Paolo Radice Paolo Peterlongo Giulietta Scuvera Stefano Fortuzzi Natalia Bogdanova Thilo Dörk Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Wei Zheng Martha J Shrubsole Qiuyin Cai Diana Torres Hoda Anton-Culver Vessela Kristensen François Bacot Daniel C Tessier Daniel Vincent Craig Luccarini Caroline Baynes Shahana Ahmed Mel Maranian Jacques Simard Georgia Chenevix-Trench Per Hall Paul D P Pharoah Alison M Dunning Douglas F Easton Ute Hamann

Carcinogenesis 2015 Feb 13;36(2):256-71. Epub 2015 Jan 13.

Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany,

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http://dx.doi.org/10.1093/carcin/bgu326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335262PMC
February 2015

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk.

Authors:
Wei-Yu Lin Nicola J Camp Maya Ghoussaini Jonathan Beesley Kyriaki Michailidou John L Hopper Carmel Apicella Melissa C Southey Jennifer Stone Marjanka K Schmidt Annegien Broeks Laura J Van't Veer Emiel J Th Rutgers Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Julian Peto Isabel Dos-Santos-Silva Olivia Fletcher Nichola Johnson Manjeet K Bolla Qin Wang Joe Dennis Elinor J Sawyer Timothy Cheng Ian Tomlinson Michael J Kerin Nicola Miller Frederik Marmé Harald M Surowy Barbara Burwinkel Pascal Guénel Thérèse Truong Florence Menegaux Claire Mulot Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Alvarez Daniel Herrero Hoda Anton-Culver Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Alfons Meindl Peter Lichtner Rita K Schmutzler Bertram Müller-Myhsok Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Daniel C Tessier Daniel Vincent Francois Bacot Heli Nevanlinna Kristiina Aittomäki Carl Blomqvist Sofia Khan Keitaro Matsuo Hidemi Ito Hiroji Iwata Akiyo Horio Natalia V Bogdanova Natalia N Antonenkova Thilo Dörk Annika Lindblom Sara Margolin Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Anna H Wu Chiu-Chen Tseng David Van Den Berg Daniel O Stram Patrick Neven Els Wauters Hans Wildiers Diether Lambrechts Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Paolo Radice Paolo Peterlongo Siranoush Manoukian Bernardo Bonanni Fergus J Couch Xianshu Wang Celine Vachon Kristen Purrington Graham G Giles Roger L Milne Catriona Mclean Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Jacques Simard Mark S Goldberg France Labrèche Martine Dumont Soo Hwang Teo Cheng Har Yip Norhashimah Hassan Eranga Nishanthie Vithana Vessela Kristensen Wei Zheng Sandra Deming-Halverson Martha J Shrubsole Jirong Long Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Saila Kauppila Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Montserrat García-Closas Jonine Figueroa Jolanta Lissowska Louise Brinton Kamila Czene Hatef Darabi Mikael Eriksson Judith S Brand Maartje J Hooning Antoinette Hollestelle Ans M W Van Den Ouweland Agnes Jager Jingmei Li Jianjun Liu Keith Humphreys Xiao-Ou Shu Wei Lu Yu-Tang Gao Hui Cai Simon S Cross Malcolm W R Reed William Blot Lisa B Signorello Qiuyin Cai Paul D P Pharoah Barbara Perkins Mitul Shah Fiona M Blows Daehee Kang Keun-Young Yoo Dong-Young Noh Mikael Hartman Hui Miao Kee Seng Chia Thomas Choudary Putti Ute Hamann Craig Luccarini Caroline Baynes Shahana Ahmed Mel Maranian Catherine S Healey Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James Mckay Susan Slager Amanda E Toland Drakoulis Yannoukakos Chen-Yang Shen Chia-Ni Hsiung Pei-Ei Wu Shian-Ling Ding Alan Ashworth Michael Jones Nick Orr Anthony J Swerdlow Helen Tsimiklis Enes Makalic Daniel F Schmidt Quang M Bui Stephen J Chanock David J Hunter Rebecca Hein Norbert Dahmen Lars Beckmann Kirsimari Aaltonen Taru A Muranen Tuomas Heikkinen Astrid Irwanto Nazneen Rahman Clare A Turnbull Quinten Waisfisz Hanne E J Meijers-Heijboer Muriel A Adank Rob B Van Der Luijt Per Hall Georgia Chenevix-Trench Alison Dunning Douglas F Easton Angela Cox

Hum Mol Genet 2015 Jan 28;24(1):285-98. Epub 2014 Aug 28.

Department of Oncology, University of Sheffield Medical School, Sheffield S10 2RX, UK

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http://dx.doi.org/10.1093/hmg/ddu431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334820PMC
January 2015

Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1.

Authors:
Dylan M Glubb Mel J Maranian Kyriaki Michailidou Karen A Pooley Kerstin B Meyer Siddhartha Kar Saskia Carlebur Martin O'Reilly Joshua A Betts Kristine M Hillman Susanne Kaufmann Jonathan Beesley Sander Canisius John L Hopper Melissa C Southey Helen Tsimiklis Carmel Apicella Marjanka K Schmidt Annegien Broeks Frans B Hogervorst C Ellen van der Schoot Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Peter A Fasching Matthias Ruebner Arif B Ekici Matthias W Beckmann Julian Peto Isabel dos-Santos-Silva Olivia Fletcher Nichola Johnson Paul D P Pharoah Manjeet K Bolla Qin Wang Joe Dennis Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Barbara Burwinkel Frederik Marme Rongxi Yang Harald Surowy Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Anna González-Neira Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Hoda Anton-Culver Susan L Neuhausen Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Alfons Meindl Rita K Schmutzler Hiltrud Brauch Yon-Dschun Ko Thomas Brüning Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Keitaro Matsuo Hidemi Ito Hiroji Iwata Hideo Tanaka Thilo Dörk Natalia V Bogdanova Sonja Helbig Annika Lindblom Sara Margolin Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Anna H Wu Chiu-chen Tseng David Van Den Berg Daniel O Stram Diether Lambrechts Hui Zhao Caroline Weltens Erik van Limbergen Jenny Chang-Claude Dieter Flesch-Janys Anja Rudolph Petra Seibold Paolo Radice Paolo Peterlongo Monica Barile Fabio Capra Fergus J Couch Janet E Olson Emily Hallberg Celine Vachon Graham G Giles Roger L Milne Catriona McLean Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Jacques Simard Mark S Goldberg France Labrèche Martine Dumont Soo Hwang Teo Cheng Har Yip Mee-Hoong See Belinda Cornes Ching-Yu Cheng M Kamran Ikram Vessela Kristensen Wei Zheng Sandra L Halverson Martha Shrubsole Jirong Long Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Saila Kauppila Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Montserrat García-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Kamila Czene Daniel Klevebring Hatef Darabi Mikael Eriksson Maartje J Hooning Antoinette Hollestelle John W M Martens J Margriet Collée Per Hall Jingmei Li Keith Humphreys Xiao-Ou Shu Wei Lu Yu-Tang Gao Hui Cai Angela Cox Simon S Cross Malcolm W R Reed William Blot Lisa B Signorello Qiuyin Cai Mitul Shah Maya Ghoussaini Daehee Kang Ji-Yeob Choi Sue K Park Dong-Young Noh Mikael Hartman Hui Miao Wei Yen Lim Anthony Tang Ute Hamann Diana Torres Anna Jakubowska Jan Lubinski Katarzyna Jaworska Katarzyna Durda Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James McKay Curtis Olswold Susan Slager Amanda E Toland Drakoulis Yannoukakos Chen-Yang Shen Pei-Ei Wu Jyh-Cherng Yu Ming-Feng Hou Anthony Swerdlow Alan Ashworth Nick Orr Michael Jones Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot Craig Luccarini Caroline Baynes Shahana Ahmed Catherine S Healey Melissa A Brown Bruce A J Ponder Georgia Chenevix-Trench Deborah J Thompson Stacey L Edwards Douglas F Easton Alison M Dunning Juliet D French

Am J Hum Genet 2015 Jan 18;96(1):5-20. Epub 2014 Dec 18.

Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4029, Australia; School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, QLD 4072, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289692PMC
January 2015

Growth and metastatic behavior of molecularly well-characterized human breast cancer cell lines in mice.

Breast Cancer Res Treat 2014 Nov 30;148(1):19-31. Epub 2014 Sep 30.

Department of Medical Oncology and Cancer Genomics Centre, Erasmus University Medical Center - Daniel den Hoed Cancer Center, 3000 CA, Rotterdam, The Netherlands,

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November 2014

Analysis of TP53 mutation status in human cancer cell lines: a reassessment.

Hum Mutat 2014 Jun 6;35(6):756-65. Epub 2014 May 6.

Université Pierre et Marie Curie-Paris 6, Paris, 75005, France.

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http://doi.wiley.com/10.1002/humu.22556
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451114PMC
June 2014

2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy.

Authors:
Jingmei Li Linda S Lindström Jia N Foo Sajjad Rafiq Marjanka K Schmidt Paul D P Pharoah Kyriaki Michailidou Joe Dennis Manjeet K Bolla Qin Wang Laura J Van 't Veer Sten Cornelissen Emiel Rutgers Melissa C Southey Carmel Apicella Gillian S Dite John L Hopper Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Carl Blomqvist Taru A Muranen Kristiina Aittomäki Annika Lindblom Sara Margolin Arto Mannermaa Veli-Matti Kosma Jaana M Hartikainen Vesa Kataja Georgia Chenevix-Trench Kelly-Anne Phillips Sue-Anne McLachlan Diether Lambrechts Bernard Thienpont Ann Smeets Hans Wildiers Jenny Chang-Claude Dieter Flesch-Janys Petra Seibold Anja Rudolph Graham G Giles Laura Baglietto Gianluca Severi Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Vessela Kristensen Grethe I Grenaker Alnæs Anne-Lise Borresen-Dale Silje Nord Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Peter Devilee Robert Tollenaar Caroline Seynaeve Maartje Hooning Mieke Kriege Antoinette Hollestelle Ans van den Ouweland Yi Li Ute Hamann Diana Torres Hans U Ulmer Thomas Rüdiger Chen-Yang Shen Chia-Ni Hsiung Pei-Ei Wu Shou-Tung Chen Soo Hwang Teo Nur Aishah Mohd Taib Cheng Har Yip Gwo Fuang Ho Keitaro Matsuo Hidemi Ito Hiroji Iwata Kazuo Tajima Daehee Kang Ji-Yeob Choi Sue K Park Keun-Young Yoo Tom Maishman William J Tapper Alison Dunning Mitul Shah Robert Luben Judith Brown Chiea Chuen Khor Diana M Eccles Heli Nevanlinna Douglas Easton Keith Humphreys Jianjun Liu Per Hall Kamila Czene

Nat Commun 2014 Jun 17;5:4051. Epub 2014 Jun 17.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, 171 77 Stockholm, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082638PMC
June 2014

Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study.

Authors:
Nichola Johnson Frank Dudbridge Nick Orr Lorna Gibson Michael E Jones Minouk J Schoemaker Elizabeth J Folkerd Ben P Haynes John L Hopper Melissa C Southey Gillian S Dite Carmel Apicella Marjanka K Schmidt Annegien Broeks Laura J Van't Veer Femke Atsma Kenneth Muir Artitaya Lophatananon Peter A Fasching Matthias W Beckmann Arif B Ekici Stefan P Renner Elinor Sawyer Ian Tomlinson Michael Kerin Nicola Miller Barbara Burwinkel Frederik Marme Andreas Schneeweiss Christof Sohn Pascal Guénel Therese Truong Emilie Cordina Florence Menegaux Stig E Bojesen Børge G Nordestgaard Henrik Flyger Roger Milne M Pilar Zamora Jose Ignacio Arias Perez Javier Benitez Leslie Bernstein Hoda Anton-Culver Argyrios Ziogas Christina Clarke Dur Hermann Brenner Heiko Müller Volker Arndt Aida Karina Dieffenbach Alfons Meindl Joerg Heil Claus R Bartram Rita K Schmutzler Hiltrud Brauch Christina Justenhoven Yon-Dschun Ko Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Keitaro Matsuo Thilo Dörk Natalia V Bogdanova Natalia N Antonenkova Annika Lindblom Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Georgia Chenevix-Trench Jonathan Beesley Anna H Wu David Van den Berg Chiu-Chen Tseng Diether Lambrechts Dominiek Smeets Patrick Neven Hans Wildiers Jenny Chang-Claude Anja Rudolph Stefan Nickels Dieter Flesch-Janys Paolo Radice Paolo Peterlongo Bernardo Bonanni Valeria Pensotti Fergus J Couch Janet E Olson Xianshu Wang Zachary Fredericksen Vernon S Pankratz Graham G Giles Gianluca Severi Laura Baglietto Chris Haiman Jacques Simard Mark S Goldberg France Labrèche Martine Dumont Penny Soucy Soo Teo Cheng Har Yip Sze Yee Phuah Belinda K Cornes Vessela N Kristensen Grethe Grenaker Alnæs Anne-Lise Børresen-Dale Wei Zheng Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Peter Devillee Jonine Figueroa Stephen J Chanock Jolanta Lissowska Mark E Sherman Per Hall Nils Schoof Maartje Hooning Antoinette Hollestelle Rogier A Oldenburg Madeleine Tilanus-Linthorst Jianjun Liu Angie Cox Ian W Brock Malcolm W R Reed Simon S Cross William Blot Lisa B Signorello Paul D P Pharoah Alison M Dunning Mitul Shah Daehee Kang Dong-Young Noh Sue K Park Ji-Yeob Choi Mikael Hartman Hui Miao Wei Yen Lim Anthony Tang Ute Hamann Asta Försti Thomas Rüdiger Hans Ulrich Ulmer Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James McKay Susan Slager Amanda E Toland Celine Vachon Drakoulis Yannoukakos Chen-Yang Shen Jyh-Cherng Yu Chiun-Sheng Huang Ming-Feng Hou Anna González-Neira Daniel C Tessier Daniel Vincent Francois Bacot Craig Luccarini Joe Dennis Kyriaki Michailidou Manjeet K Bolla Jean Wang Douglas F Easton Montserrat García-Closas Mitch Dowsett Alan Ashworth Anthony J Swerdlow Julian Peto Isabel dos Santos Silva Olivia Fletcher

Breast Cancer Res 2014 May 26;16(3):R51. Epub 2014 May 26.

Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, 237 Fulham Road, London, SW3 6JB, UK.

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http://dx.doi.org/10.1186/bcr3662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522594PMC
May 2014

A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium.

Authors:
Roger L Milne Jesús Herranz Kyriaki Michailidou Joe Dennis Jonathan P Tyrer M Pilar Zamora José Ignacio Arias-Perez Anna González-Neira Guillermo Pita M Rosario Alonso Qin Wang Manjeet K Bolla Kamila Czene Mikael Eriksson Keith Humphreys Hatef Darabi Jingmei Li Hoda Anton-Culver Susan L Neuhausen Argyrios Ziogas Christina A Clarke John L Hopper Gillian S Dite Carmel Apicella Melissa C Southey Georgia Chenevix-Trench Anthony Swerdlow Alan Ashworth Nicholas Orr Minouk Schoemaker Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Stig E Bojesen Børge G Nordestgaard Henrik Flyger Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Xianshu Wang Janet E Olson Celine Vachon Kristen Purrington Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Alison M Dunning Mitul Shah Pascal Guénel Thérèse Truong Marie Sanchez Claire Mulot Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Annika Lindblom Sara Margolin Maartje J Hooning Antoinette Hollestelle J Margriet Collée Agnes Jager Angela Cox Ian W Brock Malcolm W R Reed Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Jacques Simard Martine Dumont Penny Soucy Thilo Dörk Natalia V Bogdanova Ute Hamann Asta Försti Thomas Rüdiger Hans-Ulrich Ulmer Peter A Fasching Lothar Häberle Arif B Ekici Matthias W Beckmann Olivia Fletcher Nichola Johnson Isabel dos Santos Silva Julian Peto Paolo Radice Paolo Peterlongo Bernard Peissel Paolo Mariani Graham G Giles Gianluca Severi Laura Baglietto Elinor Sawyer Ian Tomlinson Michael Kerin Nicola Miller Federik Marme Barbara Burwinkel Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Diether Lambrechts Betul T Yesilyurt Giuseppe Floris Karin Leunen Grethe Grenaker Alnæs Vessela Kristensen Anne-Lise Børresen-Dale Montserrat García-Closas Stephen J Chanock Jolanta Lissowska Jonine D Figueroa Marjanka K Schmidt Annegien Broeks Senno Verhoef Emiel J Rutgers Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Fergus J Couch Amanda E Toland Drakoulis Yannoukakos Paul D P Pharoah Per Hall Javier Benítez Núria Malats Douglas F Easton

Hum Mol Genet 2014 Apr 15;23(7):1934-46. Epub 2013 Nov 15.

Human Cancer Genetics Programme and.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943524PMC
April 2014

Genetic predisposition to in situ and invasive lobular carcinoma of the breast.

Authors:
Elinor Sawyer Rebecca Roylance Christos Petridis Mark N Brook Salpie Nowinski Efterpi Papouli Olivia Fletcher Sarah Pinder Andrew Hanby Kelly Kohut Patricia Gorman Michele Caneppele Julian Peto Isabel Dos Santos Silva Nichola Johnson Ruth Swann Miriam Dwek Katherine-Anne Perkins Cheryl Gillett Richard Houlston Gillian Ross Paolo De Ieso Melissa C Southey John L Hopper Elena Provenzano Carmel Apicella Jelle Wesseling Sten Cornelissen Renske Keeman Peter A Fasching Sebastian M Jud Arif B Ekici Matthias W Beckmann Michael J Kerin Federick Marme Andreas Schneeweiss Christof Sohn Barbara Burwinkel Pascal Guénel Therese Truong Pierre Laurent-Puig Pierre Kerbrat Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Roger L Milne Jose Ignacio Arias Perez Primitiva Menéndez Javier Benitez Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Alfons Meindl Peter Lichtner Rita K Schmutzler Magdalena Lochmann Hiltrud Brauch Hans-Peter Fischer Yon-Dschun Ko Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Natalia V Bogdanova Thilo Dörk Annika Lindblom Sara Margolin Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Georgia Chenevix-Trench Kconfab Investigators Diether Lambrechts Caroline Weltens Erik Van Limbergen Sigrid Hatse Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Paolo Radice Paolo Peterlongo Bernardo Bonanni Sara Volorio Graham G Giles Gianluca Severi Laura Baglietto Catriona A McLean Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Jacques Simard Mark S Goldberg France Labrèche Martine Dumont Vessela Kristensen Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Saila Kauppila Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Peter Devillee Rob A E M Tollenaar Caroline M Seynaeve Mieke Kriege Jonine Figueroa Stephen J Chanock Mark E Sherman Maartje J Hooning Antoinette Hollestelle Ans M W van den Ouweland Carolien H M van Deurzen Jingmei Li Kamila Czene Keith Humphreys Angela Cox Simon S Cross Malcolm W R Reed Mitul Shah Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Anthony Swerdlow Alan Ashworth Nicholas Orr Minouk Schoemaker Fergus J Couch Emily Hallberg Anna González-Neira Guillermo Pita M Rosario Alonso Daniel C Tessier Daniel Vincent Francois Bacot Manjeet K Bolla Qin Wang Joe Dennis Kyriaki Michailidou Alison M Dunning Per Hall Doug Easton Paul Pharoah Marjanka K Schmidt Ian Tomlinson Montserrat Garcia-Closas

PLoS Genet 2014 Apr 17;10(4):e1004285. Epub 2014 Apr 17.

Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom; Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, United Kingdom.

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April 2014

Large-scale genotyping identifies 41 new loci associated with breast cancer risk.

Authors:
Kyriaki Michailidou Per Hall Anna Gonzalez-Neira Maya Ghoussaini Joe Dennis Roger L Milne Marjanka K Schmidt Jenny Chang-Claude Stig E Bojesen Manjeet K Bolla Qin Wang Ed Dicks Andrew Lee Clare Turnbull Nazneen Rahman Olivia Fletcher Julian Peto Lorna Gibson Isabel Dos Santos Silva Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Kamila Czene Astrid Irwanto Jianjun Liu Quinten Waisfisz Hanne Meijers-Heijboer Muriel Adank Rob B van der Luijt Rebecca Hein Norbert Dahmen Lars Beckman Alfons Meindl Rita K Schmutzler Bertram Müller-Myhsok Peter Lichtner John L Hopper Melissa C Southey Enes Makalic Daniel F Schmidt Andre G Uitterlinden Albert Hofman David J Hunter Stephen J Chanock Daniel Vincent François Bacot Daniel C Tessier Sander Canisius Lodewyk F A Wessels Christopher A Haiman Mitul Shah Robert Luben Judith Brown Craig Luccarini Nils Schoof Keith Humphreys Jingmei Li Børge G Nordestgaard Sune F Nielsen Henrik Flyger Fergus J Couch Xianshu Wang Celine Vachon Kristen N Stevens Diether Lambrechts Matthieu Moisse Robert Paridaens Marie-Rose Christiaens Anja Rudolph Stefan Nickels Dieter Flesch-Janys Nichola Johnson Zoe Aitken Kirsimari Aaltonen Tuomas Heikkinen Annegien Broeks Laura J Van't Veer C Ellen van der Schoot Pascal Guénel Thérèse Truong Pierre Laurent-Puig Florence Menegaux Frederik Marme Andreas Schneeweiss Christof Sohn Barbara Burwinkel M Pilar Zamora Jose Ignacio Arias Perez Guillermo Pita M Rosario Alonso Angela Cox Ian W Brock Simon S Cross Malcolm W R Reed Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Brian E Henderson Fredrick Schumacher Loic Le Marchand Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Annika Lindblom Sara Margolin Maartje J Hooning Antoinette Hollestelle Ans M W van den Ouweland Agnes Jager Quang M Bui Jennifer Stone Gillian S Dite Carmel Apicella Helen Tsimiklis Graham G Giles Gianluca Severi Laura Baglietto Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Hermann Brenner Heiko Müller Volker Arndt Christa Stegmaier Anthony Swerdlow Alan Ashworth Nick Orr Michael Jones Jonine Figueroa Jolanta Lissowska Louise Brinton Mark S Goldberg France Labrèche Martine Dumont Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Hiltrud Brauch Ute Hamann Thomas Brüning Paolo Radice Paolo Peterlongo Siranoush Manoukian Bernardo Bonanni Peter Devilee Rob A E M Tollenaar Caroline Seynaeve Christi J van Asperen Anna Jakubowska Jan Lubinski Katarzyna Jaworska Katarzyna Durda Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Natalia V Bogdanova Natalia N Antonenkova Thilo Dörk Vessela N Kristensen Hoda Anton-Culver Susan Slager Amanda E Toland Stephen Edge Florentia Fostira Daehee Kang Keun-Young Yoo Dong-Young Noh Keitaro Matsuo Hidemi Ito Hiroji Iwata Aiko Sueta Anna H Wu Chiu-Chen Tseng David Van Den Berg Daniel O Stram Xiao-Ou Shu Wei Lu Yu-Tang Gao Hui Cai Soo Hwang Teo Cheng Har Yip Sze Yee Phuah Belinda K Cornes Mikael Hartman Hui Miao Wei Yen Lim Jen-Hwei Sng Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Chen-Yang Shen Chia-Ni Hsiung Pei-Ei Wu Shian-Ling Ding Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James McKay William J Blot Lisa B Signorello Qiuyin Cai Wei Zheng Sandra Deming-Halverson Martha Shrubsole Jirong Long Jacques Simard Montse Garcia-Closas Paul D P Pharoah Georgia Chenevix-Trench Alison M Dunning Javier Benitez Douglas F Easton

Nat Genet 2013 Apr;45(4):353-61, 361e1-2

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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April 2013

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.

Authors:
Stig E Bojesen Karen A Pooley Sharon E Johnatty Jonathan Beesley Kyriaki Michailidou Jonathan P Tyrer Stacey L Edwards Hilda A Pickett Howard C Shen Chanel E Smart Kristine M Hillman Phuong L Mai Kate Lawrenson Michael D Stutz Yi Lu Rod Karevan Nicholas Woods Rebecca L Johnston Juliet D French Xiaoqing Chen Maren Weischer Sune F Nielsen Melanie J Maranian Maya Ghoussaini Shahana Ahmed Caroline Baynes Manjeet K Bolla Qin Wang Joe Dennis Lesley McGuffog Daniel Barrowdale Andrew Lee Sue Healey Michael Lush Daniel C Tessier Daniel Vincent Françis Bacot Ignace Vergote Sandrina Lambrechts Evelyn Despierre Harvey A Risch Anna González-Neira Mary Anne Rossing Guillermo Pita Jennifer A Doherty Nuria Alvarez Melissa C Larson Brooke L Fridley Nils Schoof Jenny Chang-Claude Mine S Cicek Julian Peto Kimberly R Kalli Annegien Broeks Sebastian M Armasu Marjanka K Schmidt Linde M Braaf Boris Winterhoff Heli Nevanlinna Gottfried E Konecny Diether Lambrechts Lisa Rogmann Pascal Guénel Attila Teoman Roger L Milne Joaquin J Garcia Angela Cox Vijayalakshmi Shridhar Barbara Burwinkel Frederik Marme Rebecca Hein Elinor J Sawyer Christopher A Haiman Shan Wang-Gohrke Irene L Andrulis Kirsten B Moysich John L Hopper Kunle Odunsi Annika Lindblom Graham G Giles Hermann Brenner Jacques Simard Galina Lurie Peter A Fasching Michael E Carney Paolo Radice Lynne R Wilkens Anthony Swerdlow Marc T Goodman Hiltrud Brauch Montserrat Garcia-Closas Peter Hillemanns Robert Winqvist Matthias Dürst Peter Devilee Ingo Runnebaum Anna Jakubowska Jan Lubinski Arto Mannermaa Ralf Butzow Natalia V Bogdanova Thilo Dörk Liisa M Pelttari Wei Zheng Arto Leminen Hoda Anton-Culver Clareann H Bunker Vessela Kristensen Roberta B Ness Kenneth Muir Robert Edwards Alfons Meindl Florian Heitz Keitaro Matsuo Andreas du Bois Anna H Wu Philipp Harter Soo-Hwang Teo Ira Schwaab Xiao-Ou Shu William Blot Satoyo Hosono Daehee Kang Toru Nakanishi Mikael Hartman Yasushi Yatabe Ute Hamann Beth Y Karlan Suleeporn Sangrajrang Susanne Krüger Kjaer Valerie Gaborieau Allan Jensen Diana Eccles Estrid Høgdall Chen-Yang Shen Judith Brown Yin Ling Woo Mitul Shah Mat Adenan Noor Azmi Robert Luben Siti Zawiah Omar Kamila Czene Robert A Vierkant Børge G Nordestgaard Henrik Flyger Celine Vachon Janet E Olson Xianshu Wang Douglas A Levine Anja Rudolph Rachel Palmieri Weber Dieter Flesch-Janys Edwin Iversen Stefan Nickels Joellen M Schildkraut Isabel Dos Santos Silva Daniel W Cramer Lorna Gibson Kathryn L Terry Olivia Fletcher Allison F Vitonis C Ellen van der Schoot Elizabeth M Poole Frans B L Hogervorst Shelley S Tworoger Jianjun Liu Elisa V Bandera Jingmei Li Sara H Olson Keith Humphreys Irene Orlow Carl Blomqvist Lorna Rodriguez-Rodriguez Kristiina Aittomäki Helga B Salvesen Taru A Muranen Elisabeth Wik Barbara Brouwers Camilla Krakstad Els Wauters Mari K Halle Hans Wildiers Lambertus A Kiemeney Claire Mulot Katja K Aben Pierre Laurent-Puig Anne Mvan Altena Thérèse Truong Leon F A G Massuger Javier Benitez Tanja Pejovic Jose Ignacio Arias Perez Maureen Hoatlin M Pilar Zamora Linda S Cook Sabapathy P Balasubramanian Linda E Kelemen Andreas Schneeweiss Nhu D Le Christof Sohn Angela Brooks-Wilson Ian Tomlinson Michael J Kerin Nicola Miller Cezary Cybulski Brian E Henderson Janusz Menkiszak Fredrick Schumacher Nicolas Wentzensen Loic Le Marchand Hannah P Yang Anna Marie Mulligan Gord Glendon Svend Aage Engelholm Julia A Knight Claus K Høgdall Carmel Apicella Martin Gore Helen Tsimiklis Honglin Song Melissa C Southey Agnes Jager Ans M Wvan den Ouweland Robert Brown John W M Martens James M Flanagan Mieke Kriege James Paul Sara Margolin Nadeem Siddiqui Gianluca Severi Alice S Whittemore Laura Baglietto Valerie McGuire Christa Stegmaier Weiva Sieh Heiko Müller Volker Arndt France Labrèche Yu-Tang Gao Mark S Goldberg Gong Yang Martine Dumont John R McLaughlin Arndt Hartmann Arif B Ekici Matthias W Beckmann Catherine M Phelan Michael P Lux Jenny Permuth-Wey Bernard Peissel Thomas A Sellers Filomena Ficarazzi Monica Barile Argyrios Ziogas Alan Ashworth Aleksandra Gentry-Maharaj Michael Jones Susan J Ramus Nick Orr Usha Menon Celeste L Pearce Thomas Brüning Malcolm C Pike Yon-Dschun Ko Jolanta Lissowska Jonine Figueroa Jolanta Kupryjanczyk Stephen J Chanock Agnieszka Dansonka-Mieszkowska Arja Jukkola-Vuorinen Iwona K Rzepecka Katri Pylkäs Mariusz Bidzinski Saila Kauppila Antoinette Hollestelle Caroline Seynaeve Rob A E M Tollenaar Katarzyna Durda Katarzyna Jaworska Jaana M Hartikainen Veli-Matti Kosma Vesa Kataja Natalia N Antonenkova Jirong Long Martha Shrubsole Sandra Deming-Halverson Artitaya Lophatananon Pornthep Siriwanarangsan Sarah Stewart-Brown Nina Ditsch Peter Lichtner Rita K Schmutzler Hidemi Ito Hiroji Iwata Kazuo Tajima Chiu-Chen Tseng Daniel O Stram David van den Berg Cheng Har Yip M Kamran Ikram Yew-Ching Teh Hui Cai Wei Lu Lisa B Signorello Qiuyin Cai Dong-Young Noh Keun-Young Yoo Hui Miao Philip Tsau-Choong Iau Yik Ying Teo James McKay Charles Shapiro Foluso Ademuyiwa George Fountzilas Chia-Ni Hsiung Jyh-Cherng Yu Ming-Feng Hou Catherine S Healey Craig Luccarini Susan Peock Dominique Stoppa-Lyonnet Paolo Peterlongo Timothy R Rebbeck Marion Piedmonte Christian F Singer Eitan Friedman Mads Thomassen Kenneth Offit Thomas V O Hansen Susan L Neuhausen Csilla I Szabo Ignacio Blanco Judy Garber Steven A Narod Jeffrey N Weitzel Marco Montagna Edith Olah Andrew K Godwin Drakoulis Yannoukakos David E Goldgar Trinidad Caldes Evgeny N Imyanitov Laima Tihomirova Banu K Arun Ian Campbell Arjen R Mensenkamp Christi J van Asperen Kees E P van Roozendaal Hanne Meijers-Heijboer J Margriet Collée Jan C Oosterwijk Maartje J Hooning Matti A Rookus Rob B van der Luijt Theo A Mvan Os D Gareth Evans Debra Frost Elena Fineberg Julian Barwell Lisa Walker M John Kennedy Radka Platte Rosemarie Davidson Steve D Ellis Trevor Cole Brigitte Bressac-de Paillerets Bruno Buecher Francesca Damiola Laurence Faivre Marc Frenay Olga M Sinilnikova Olivier Caron Sophie Giraud Sylvie Mazoyer Valérie Bonadona Virginie Caux-Moncoutier Aleksandra Toloczko-Grabarek Jacek Gronwald Tomasz Byrski Amanda B Spurdle Bernardo Bonanni Daniela Zaffaroni Giuseppe Giannini Loris Bernard Riccardo Dolcetti Siranoush Manoukian Norbert Arnold Christoph Engel Helmut Deissler Kerstin Rhiem Dieter Niederacher Hansjoerg Plendl Christian Sutter Barbara Wappenschmidt Ake Borg Beatrice Melin Johanna Rantala Maria Soller Katherine L Nathanson Susan M Domchek Gustavo C Rodriguez Ritu Salani Daphne Gschwantler Kaulich Muy-Kheng Tea Shani Shimon Paluch Yael Laitman Anne-Bine Skytte Torben A Kruse Uffe Birk Jensen Mark Robson Anne-Marie Gerdes Bent Ejlertsen Lenka Foretova Sharon A Savage Jenny Lester Penny Soucy Karoline B Kuchenbaecker Curtis Olswold Julie M Cunningham Susan Slager Vernon S Pankratz Ed Dicks Sunil R Lakhani Fergus J Couch Per Hall Alvaro N A Monteiro Simon A Gayther Paul D P Pharoah Roger R Reddel Ellen L Goode Mark H Greene Douglas F Easton Andrew Berchuck Antonis C Antoniou Georgia Chenevix-Trench Alison M Dunning

Nat Genet 2013 Apr;45(4):371-84, 384e1-2

Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/ng.2566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670748PMC
April 2013

Genome-wide association studies identify four ER negative-specific breast cancer risk loci.

Authors:
Montserrat Garcia-Closas Fergus J Couch Sara Lindstrom Kyriaki Michailidou Marjanka K Schmidt Mark N Brook Nick Orr Suhn Kyong Rhie Elio Riboli Heather S Feigelson Loic Le Marchand Julie E Buring Diana Eccles Penelope Miron Peter A Fasching Hiltrud Brauch Jenny Chang-Claude Jane Carpenter Andrew K Godwin Heli Nevanlinna Graham G Giles Angela Cox John L Hopper Manjeet K Bolla Qin Wang Joe Dennis Ed Dicks Will J Howat Nils Schoof Stig E Bojesen Diether Lambrechts Annegien Broeks Irene L Andrulis Pascal Guénel Barbara Burwinkel Elinor J Sawyer Antoinette Hollestelle Olivia Fletcher Robert Winqvist Hermann Brenner Arto Mannermaa Ute Hamann Alfons Meindl Annika Lindblom Wei Zheng Peter Devillee Mark S Goldberg Jan Lubinski Vessela Kristensen Anthony Swerdlow Hoda Anton-Culver Thilo Dörk Kenneth Muir Keitaro Matsuo Anna H Wu Paolo Radice Soo Hwang Teo Xiao-Ou Shu William Blot Daehee Kang Mikael Hartman Suleeporn Sangrajrang Chen-Yang Shen Melissa C Southey Daniel J Park Fleur Hammet Jennifer Stone Laura J Van't Veer Emiel J Rutgers Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Julian Peto Michael G Schrauder Arif B Ekici Matthias W Beckmann Isabel Dos Santos Silva Nichola Johnson Helen Warren Ian Tomlinson Michael J Kerin Nicola Miller Federick Marme Andreas Schneeweiss Christof Sohn Therese Truong Pierre Laurent-Puig Pierre Kerbrat Børge G Nordestgaard Sune F Nielsen Henrik Flyger Roger L Milne Jose Ignacio Arias Perez Primitiva Menéndez Heiko Müller Volker Arndt Christa Stegmaier Peter Lichtner Magdalena Lochmann Christina Justenhoven Yon-Dschun Ko Taru A Muranen Kristiina Aittomäki Carl Blomqvist Dario Greco Tuomas Heikkinen Hidemi Ito Hiroji Iwata Yasushi Yatabe Natalia N Antonenkova Sara Margolin Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Rosemary Balleine Chiu-Chen Tseng David Van Den Berg Daniel O Stram Patrick Neven Anne-Sophie Dieudonné Karin Leunen Anja Rudolph Stefan Nickels Dieter Flesch-Janys Paolo Peterlongo Bernard Peissel Loris Bernard Janet E Olson Xianshu Wang Kristen Stevens Gianluca Severi Laura Baglietto Catriona McLean Gerhard A Coetzee Ye Feng Brian E Henderson Fredrick Schumacher Natalia V Bogdanova France Labrèche Martine Dumont Cheng Har Yip Nur Aishah Mohd Taib Ching-Yu Cheng Martha Shrubsole Jirong Long Katri Pylkäs Arja Jukkola-Vuorinen Saila Kauppila Julia A Knight Gord Glendon Anna Marie Mulligan Robertus A E M Tollenaar Caroline M Seynaeve Mieke Kriege Maartje J Hooning Ans M W van den Ouweland Carolien H M van Deurzen Wei Lu Yu-Tang Gao Hui Cai Sabapathy P Balasubramanian Simon S Cross Malcolm W R Reed Lisa Signorello Qiuyin Cai Mitul Shah Hui Miao Ching Wan Chan Kee Seng Chia Anna Jakubowska Katarzyna Jaworska Katarzyna Durda Chia-Ni Hsiung Pei-Ei Wu Jyh-Cherng Yu Alan Ashworth Michael Jones Daniel C Tessier Anna González-Neira Guillermo Pita M Rosario Alonso Daniel Vincent Francois Bacot Christine B Ambrosone Elisa V Bandera Esther M John Gary K Chen Jennifer J Hu Jorge L Rodriguez-Gil Leslie Bernstein Michael F Press Regina G Ziegler Robert M Millikan Sandra L Deming-Halverson Sarah Nyante Sue A Ingles Quinten Waisfisz Helen Tsimiklis Enes Makalic Daniel Schmidt Minh Bui Lorna Gibson Bertram Müller-Myhsok Rita K Schmutzler Rebecca Hein Norbert Dahmen Lars Beckmann Kirsimari Aaltonen Kamila Czene Astrid Irwanto Jianjun Liu Clare Turnbull Nazneen Rahman Hanne Meijers-Heijboer Andre G Uitterlinden Fernando Rivadeneira Curtis Olswold Susan Slager Robert Pilarski Foluso Ademuyiwa Irene Konstantopoulou Nicholas G Martin Grant W Montgomery Dennis J Slamon Claudia Rauh Michael P Lux Sebastian M Jud Thomas Bruning Joellen Weaver Priyanka Sharma Harsh Pathak Will Tapper Sue Gerty Lorraine Durcan Dimitrios Trichopoulos Rosario Tumino Petra H Peeters Rudolf Kaaks Daniele Campa Federico Canzian Elisabete Weiderpass Mattias Johansson Kay-Tee Khaw Ruth Travis Françoise Clavel-Chapelon Laurence N Kolonel Constance Chen Andy Beck Susan E Hankinson Christine D Berg Robert N Hoover Jolanta Lissowska Jonine D Figueroa Daniel I Chasman Mia M Gaudet W Ryan Diver Walter C Willett David J Hunter Jacques Simard Javier Benitez Alison M Dunning Mark E Sherman Georgia Chenevix-Trench Stephen J Chanock Per Hall Paul D P Pharoah Celine Vachon Douglas F Easton Christopher A Haiman Peter Kraft

Nat Genet 2013 Apr;45(4):392-8, 398e1-2

1] Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, UK. [2] Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK. [3].

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April 2013

Loss of E-cadherin is not a necessity for epithelial to mesenchymal transition in human breast cancer.

Breast Cancer Res Treat 2013 Feb 22;138(1):47-57. Epub 2013 Jan 22.

Department of Medical Oncology, Josephine Nefkens Institute, Erasmus University Medical Center-Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.

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February 2013

E-cadherin promotor methylation and mutation are inversely related to motility capacity of breast cancer cells.

Breast Cancer Res Treat 2012 Nov 29;136(2):365-77. Epub 2012 Sep 29.

Laboratory for Experimental Surgical Oncology, Section Surgical Oncology, Daniel den Hoed Cancer Center, Erasmus University Medical Centre, PO Box 1738, 3000 DR, Rotterdam, The Netherlands.

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November 2012

9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium.

Authors:
Helen Warren Frank Dudbridge Olivia Fletcher Nick Orr Nichola Johnson John L Hopper Carmel Apicella Melissa C Southey Maryam Mahmoodi Marjanka K Schmidt Annegien Broeks Sten Cornelissen Linda M Braaf Kenneth R Muir Artitaya Lophatananon Arkom Chaiwerawattana Surapon Wiangnon Peter A Fasching Matthias W Beckmann Arif B Ekici Ruediger Schulz-Wendtland Elinor J Sawyer Ian Tomlinson Michael Kerin Barbara Burwinkel Frederik Marme Andreas Schneeweiss Christof Sohn Pascal Guénel Thérèse Truong Pierre Laurent-Puig Claire Mulot Stig E Bojesen Sune F Nielsen Henrik Flyger Børge G Nordestgaard Roger L Milne Javier Benítez José-Ignacio Arias-Pérez M Pilar Zamora Hoda Anton-Culver Argyrios Ziogas Leslie Bernstein Christina Clarke Dur Hermann Brenner Heiko Müller Volker Arndt Anne Langheinz Alfons Meindl Michael Golatta Claus R Bartram Rita K Schmutzler Hiltrud Brauch Christina Justenhoven Thomas Brüning Jenny Chang-Claude Shan Wang-Gohrke Ursula Eilber Thilo Dörk Peter Schürmann Michael Bremer Peter Hillemanns Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Natalia Bogdanova Natalia Antonenkova Yuriy Rogov Marina Bermisheva Darya Prokofyeva Guzel Zinnatullina Elza Khusnutdinova Annika Lindblom Sara Margolin Arto Mannermaa Veli-Matti Kosma Jaana M Hartikainen Vesa Kataja Georgia Chenevix-Trench Jonathan Beesley Xiaoqing Chen Diether Lambrechts Ann Smeets Robert Paridaens Caroline Weltens Dieter Flesch-Janys Katharina Buck Sabine Behrens Paolo Peterlongo Loris Bernard Siranoush Manoukian Paolo Radice Fergus J Couch Celine Vachon Xianshu Wang Janet Olson Graham Giles Laura Baglietto Cariona A McLean Gianluca Severi Esther M John Alexander Miron Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Irene L Andrulis Julia A Knight Anna Marie Mulligan Nayana Weerasooriya Peter Devilee Robert A E M Tollenaar John W M Martens Caroline M Seynaeve Maartje J Hooning Antoinette Hollestelle Agnes Jager Madeleine M A Tilanus-Linthorst Per Hall Kamila Czene Jianjun Liu Jingmei Li Angela Cox Simon S Cross Ian W Brock Malcolm W R Reed Paul Pharoah Fiona M Blows Alison M Dunning Maya Ghoussaini Alan Ashworth Anthony Swerdlow Michael Jones Minouk Schoemaker Douglas F Easton Manjeet Humphreys Qin Wang Julian Peto Isabel dos-Santos-Silva

Cancer Epidemiol Biomarkers Prev 2012 Oct 2;21(10):1783-91. Epub 2012 Aug 2.

Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772723PMC
October 2012

Genome-wide association analysis identifies three new breast cancer susceptibility loci.

Authors:
Maya Ghoussaini Olivia Fletcher Kyriaki Michailidou Clare Turnbull Marjanka K Schmidt Ed Dicks Joe Dennis Qin Wang Manjeet K Humphreys Craig Luccarini Caroline Baynes Don Conroy Melanie Maranian Shahana Ahmed Kristy Driver Nichola Johnson Nicholas Orr Isabel dos Santos Silva Quinten Waisfisz Hanne Meijers-Heijboer Andre G Uitterlinden Fernando Rivadeneira Per Hall Kamila Czene Astrid Irwanto Jianjun Liu Heli Nevanlinna Kristiina Aittomäki Carl Blomqvist Alfons Meindl Rita K Schmutzler Bertram Müller-Myhsok Peter Lichtner Jenny Chang-Claude Rebecca Hein Stefan Nickels Dieter Flesch-Janys Helen Tsimiklis Enes Makalic Daniel Schmidt Minh Bui John L Hopper Carmel Apicella Daniel J Park Melissa Southey David J Hunter Stephen J Chanock Annegien Broeks Senno Verhoef Frans B L Hogervorst Peter A Fasching Michael P Lux Matthias W Beckmann Arif B Ekici Elinor Sawyer Ian Tomlinson Michael Kerin Frederik Marme Andreas Schneeweiss Christof Sohn Barbara Burwinkel Pascal Guénel Thérèse Truong Emilie Cordina-Duverger Florence Menegaux Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Roger L Milne M Rosario Alonso Anna González-Neira Javier Benítez Hoda Anton-Culver Argyrios Ziogas Leslie Bernstein Christina Clarke Dur Hermann Brenner Heiko Müller Volker Arndt Christa Stegmaier Christina Justenhoven Hiltrud Brauch Thomas Brüning Shan Wang-Gohrke Ursula Eilber Thilo Dörk Peter Schürmann Michael Bremer Peter Hillemanns Natalia V Bogdanova Natalia N Antonenkova Yuri I Rogov Johann H Karstens Marina Bermisheva Darya Prokofieva Elza Khusnutdinova Annika Lindblom Sara Margolin Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Diether Lambrechts Betul T Yesilyurt Giuseppe Floris Karin Leunen Siranoush Manoukian Bernardo Bonanni Stefano Fortuzzi Paolo Peterlongo Fergus J Couch Xianshu Wang Kristen Stevens Adam Lee Graham G Giles Laura Baglietto Gianluca Severi Catriona McLean Grethe Grenaker Alnaes Vessela Kristensen Anne-Lise Børrensen-Dale Esther M John Alexander Miron Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Saila Kauppila Irene L Andrulis Gord Glendon Anna Marie Mulligan Peter Devilee Christie J van Asperen Rob A E M Tollenaar Caroline Seynaeve Jonine D Figueroa Montserrat Garcia-Closas Louise Brinton Jolanta Lissowska Maartje J Hooning Antoinette Hollestelle Rogier A Oldenburg Ans M W van den Ouweland Angela Cox Malcolm W R Reed Mitul Shah Ania Jakubowska Jan Lubinski Katarzyna Jaworska Katarzyna Durda Michael Jones Minouk Schoemaker Alan Ashworth Anthony Swerdlow Jonathan Beesley Xiaoqing Chen Kenneth R Muir Artitaya Lophatananon Suthee Rattanamongkongul Arkom Chaiwerawattana Daehee Kang Keun-Young Yoo Dong-Young Noh Chen-Yang Shen Jyh-Cherng Yu Pei-Ei Wu Chia-Ni Hsiung Annie Perkins Ruth Swann Louiza Velentzis Diana M Eccles Will J Tapper Susan M Gerty Nikki J Graham Bruce A J Ponder Georgia Chenevix-Trench Paul D P Pharoah Mark Lathrop Alison M Dunning Nazneen Rahman Julian Peto Douglas F Easton

Nat Genet 2012 Jan 22;44(3):312-8. Epub 2012 Jan 22.

Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653403PMC
January 2012

Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer.

Authors:
Roger L Milne Ellen L Goode Montserrat García-Closas Fergus J Couch Gianluca Severi Rebecca Hein Zachary Fredericksen Núria Malats M Pilar Zamora Jose Ignacio Arias Pérez Javier Benítez Thilo Dörk Peter Schürmann Johann H Karstens Peter Hillemanns Angela Cox Ian W Brock Graeme Elliot Simon S Cross Sheila Seal Clare Turnbull Anthony Renwick Nazneen Rahman Chen-Yang Shen Jyh-Cherng Yu Chiun-Sheng Huang Ming-Feng Hou Børge G Nordestgaard Stig E Bojesen Charlotte Lanng Grethe Grenaker Alnæs Vessela Kristensen Anne-Lise Børrensen-Dale John L Hopper Gillian S Dite Carmel Apicella Melissa C Southey Diether Lambrechts Betül T Yesilyurt Giuseppe Floris Karin Leunen Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James McKay Jenny Chang-Claude Shan Wang-Gohrke Paolo Radice Paolo Peterlongo Siranoush Manoukian Monica Barile Graham G Giles Laura Baglietto Esther M John Alexander Miron Stephen J Chanock Jolanta Lissowska Mark E Sherman Jonine D Figueroa Natalia V Bogdanova Natalia N Antonenkova Iosif V Zalutsky Yuri I Rogov Peter A Fasching Christian M Bayer Arif B Ekici Matthias W Beckmann Hermann Brenner Heiko Müller Volker Arndt Christa Stegmaier Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Alfons Meindl Joerg Heil Claus R Bartram Rita K Schmutzler Gilles D Thomas Robert N Hoover Olivia Fletcher Lorna J Gibson Isabel dos Santos Silva Julian Peto Stefan Nickels Dieter Flesch-Janys Hoda Anton-Culver Argyrios Ziogas Elinor Sawyer Ian Tomlinson Michael Kerin Nicola Miller Marjanka K Schmidt Annegien Broeks Laura J Van 't Veer Rob A E M Tollenaar Paul D P Pharoah Alison M Dunning Karen A Pooley Frederik Marme Andreas Schneeweiss Christof Sohn Barbara Burwinkel Anna Jakubowska Jan Lubinski Katarzyna Jaworska Katarzyna Durda Daehee Kang Keun-Young Yoo Dong-Young Noh Sei-Hyun Ahn David J Hunter Susan E Hankinson Peter Kraft Sara Lindstrom Xiaoqing Chen Jonathan Beesley Ute Hamann Volker Harth Christina Justenhoven Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Maartje Hooning Antoinette Hollestelle Rogier A Oldenburg Madeleine Tilanus-Linthorst Elza Khusnutdinova Marina Bermisheva Darya Prokofieva Albina Farahtdinova Janet E Olson Xianshu Wang Manjeet K Humphreys Qin Wang Georgia Chenevix-Trench Douglas F Easton

Cancer Epidemiol Biomarkers Prev 2011 Oct 27;20(10):2222-31. Epub 2011 Jul 27.

Genetic & Molecular Epidemiology Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164116PMC
October 2011

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium.

Authors:
Annegien Broeks Marjanka K Schmidt Mark E Sherman Fergus J Couch John L Hopper Gillian S Dite Carmel Apicella Letitia D Smith Fleur Hammet Melissa C Southey Laura J Van 't Veer Renate de Groot Vincent T H B M Smit Peter A Fasching Matthias W Beckmann Sebastian Jud Arif B Ekici Arndt Hartmann Alexander Hein Ruediger Schulz-Wendtland Barbara Burwinkel Frederik Marme Andreas Schneeweiss Hans-Peter Sinn Christof Sohn Sandrine Tchatchou Stig E Bojesen Børge G Nordestgaard Henrik Flyger David D Ørsted Diljit Kaur-Knudsen Roger L Milne Jose I Arias Pérez Pilar Zamora Primitiva Menéndez Rodríguez Javier Benítez Hiltrud Brauch Christina Justenhoven Yon-Dschun Ko Ute Hamann Hans-Peter Fischer Thomas Brüning Beate Pesch Jenny Chang-Claude Shan Wang-Gohrke Michael Bremer Johann H Karstens Peter Hillemanns Thilo Dörk Heli A Nevanlinna Tuomas Heikkinen Päivi Heikkilä Carl Blomqvist Kristiina Aittomäki Kirsimari Aaltonen Annika Lindblom Sara Margolin Arto Mannermaa Veli-Matti Kosma Jaana M Kauppinen Vesa Kataja Päivi Auvinen Matti Eskelinen Ylermi Soini Georgia Chenevix-Trench Amanda B Spurdle Jonathan Beesley Xiaoqing Chen Helene Holland Diether Lambrechts Bart Claes Thijs Vandorpe Patrick Neven Hans Wildiers Dieter Flesch-Janys Rebecca Hein Thomas Löning Matthew Kosel Zachary S Fredericksen Xianshu Wang Graham G Giles Laura Baglietto Gianluca Severi Catriona McLean Christopher A Haiman Brian E Henderson Loic Le Marchand Laurence N Kolonel Grethe Grenaker Alnæs Vessela Kristensen Anne-Lise Børresen-Dale David J Hunter Susan E Hankinson Irene L Andrulis Anna Marie Mulligan Frances P O'Malley Peter Devilee Petra E A Huijts Rob A E M Tollenaar Christi J Van Asperen Caroline S Seynaeve Stephen J Chanock Jolanta Lissowska Louise Brinton Beata Peplonska Jonine Figueroa Xiaohong R Yang Maartje J Hooning Antoinette Hollestelle Rogier A Oldenburg Agnes Jager Mieke Kriege Bahar Ozturk Geert J L H van Leenders Per Hall Kamila Czene Keith Humphreys Jianjun Liu Angela Cox Daniel Connley Helen E Cramp Simon S Cross Sabapathy P Balasubramanian Malcolm W R Reed Alison M Dunning Douglas F Easton Manjeet K Humphreys Carlos Caldas Fiona Blows Kristy Driver Elena Provenzano Jan Lubinski Anna Jakubowska Tomasz Huzarski Tomasz Byrski Cezary Cybulski Bohdan Gorski Jacek Gronwald Paul Brennan Suleeporn Sangrajrang Valerie Gaborieau Chen-Yang Shen Chia-Ni Hsiung Jyh-Cherng Yu Shou-Tung Chen Giu-Cheng Hsu Ming-Feng Hou Chiun-Sheng Huang Hoda Anton-Culver Argyrios Ziogas Paul D P Pharoah Montserrat Garcia-Closas

Hum Mol Genet 2011 Aug 19;20(16):3289-303. Epub 2011 May 19.

Department of Experimental Therapy, The Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140824PMC
August 2011

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies.

Authors:
Xiaohong R Yang Jenny Chang-Claude Ellen L Goode Fergus J Couch Heli Nevanlinna Roger L Milne Mia Gaudet Marjanka K Schmidt Annegien Broeks Angela Cox Peter A Fasching Rebecca Hein Amanda B Spurdle Fiona Blows Kristy Driver Dieter Flesch-Janys Judith Heinz Peter Sinn Alina Vrieling Tuomas Heikkinen Kristiina Aittomäki Päivi Heikkilä Carl Blomqvist Jolanta Lissowska Beata Peplonska Stephen Chanock Jonine Figueroa Louise Brinton Per Hall Kamila Czene Keith Humphreys Hatef Darabi Jianjun Liu Laura J Van 't Veer Flora E van Leeuwen Irene L Andrulis Gord Glendon Julia A Knight Anna Marie Mulligan Frances P O'Malley Nayana Weerasooriya Esther M John Matthias W Beckmann Arndt Hartmann Sebastian B Weihbrecht David L Wachter Sebastian M Jud Christian R Loehberg Laura Baglietto Dallas R English Graham G Giles Catriona A McLean Gianluca Severi Diether Lambrechts Thijs Vandorpe Caroline Weltens Robert Paridaens Ann Smeets Patrick Neven Hans Wildiers Xianshu Wang Janet E Olson Victoria Cafourek Zachary Fredericksen Matthew Kosel Celine Vachon Helen E Cramp Daniel Connley Simon S Cross Sabapathy P Balasubramanian Malcolm W R Reed Thilo Dörk Michael Bremer Andreas Meyer Johann H Karstens Aysun Ay Tjoung-Won Park-Simon Peter Hillemanns Jose Ignacio Arias Pérez Primitiva Menéndez Rodríguez Pilar Zamora Javier Benítez Yon-Dschun Ko Hans-Peter Fischer Ute Hamann Beate Pesch Thomas Brüning Christina Justenhoven Hiltrud Brauch Diana M Eccles William J Tapper Sue M Gerty Elinor J Sawyer Ian P Tomlinson Angela Jones Michael Kerin Nicola Miller Niall McInerney Hoda Anton-Culver Argyrios Ziogas Chen-Yang Shen Chia-Ni Hsiung Pei-Ei Wu Show-Lin Yang Jyh-Cherng Yu Shou-Tung Chen Giu-Cheng Hsu Christopher A Haiman Brian E Henderson Loic Le Marchand Laurence N Kolonel Annika Lindblom Sara Margolin Anna Jakubowska Jan Lubiński Tomasz Huzarski Tomasz Byrski Bohdan Górski Jacek Gronwald Maartje J Hooning Antoinette Hollestelle Ans M W van den Ouweland Agnes Jager Mieke Kriege Madeleine M A Tilanus-Linthorst Margriet Collée Shan Wang-Gohrke Katri Pylkäs Arja Jukkola-Vuorinen Kari Mononen Mervi Grip Pasi Hirvikoski Robert Winqvist Arto Mannermaa Veli-Matti Kosma Jaana Kauppinen Vesa Kataja Päivi Auvinen Ylermi Soini Reijo Sironen Stig E Bojesen David Dynnes Ørsted Diljit Kaur-Knudsen Henrik Flyger Børge G Nordestgaard Helene Holland Georgia Chenevix-Trench Siranoush Manoukian Monica Barile Paolo Radice Susan E Hankinson David J Hunter Rulla Tamimi Suleeporn Sangrajrang Paul Brennan James McKay Fabrice Odefrey Valerie Gaborieau Peter Devilee P E A Huijts R A E M Tollenaar C Seynaeve Gillian S Dite Carmel Apicella John L Hopper Fleur Hammet Helen Tsimiklis Letitia D Smith Melissa C Southey Manjeet K Humphreys Douglas Easton Paul Pharoah Mark E Sherman Montserrat Garcia-Closas

J Natl Cancer Inst 2011 Feb 29;103(3):250-63. Epub 2010 Dec 29.

Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Sciences, Rockville, MD 20852, USA.

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February 2011

Four human breast cancer cell lines with biallelic inactivating alpha-catenin gene mutations.

Breast Cancer Res Treat 2010 Jul 18;122(1):125-33. Epub 2009 Sep 18.

Department of Medical Oncology, Josephine Nefkens Institute, Erasmus University Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands.

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July 2010

Discovering moderate-risk breast cancer susceptibility genes.

Curr Opin Genet Dev 2010 Jun 24;20(3):268-76. Epub 2010 Mar 24.

Department of Medical Oncology, Josephine Nefkens Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.

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June 2010

Low-risk susceptibility alleles in 40 human breast cancer cell lines.

BMC Cancer 2009 Jul 16;9:236. Epub 2009 Jul 16.

Department of Medical Oncology, Josephine Nefkens Institute, Erasmus University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1186/1471-2407-9-236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087328PMC
July 2009

Deleterious CHEK2 1100delC and L303X mutants identified among 38 human breast cancer cell lines.

Breast Cancer Res Treat 2009 Jan 24;113(2):285-91. Epub 2008 Feb 24.

Department of Medical Oncology, Josephine Nefkens Institute, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

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January 2009

Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines.

Mol Cancer Res 2007 Feb;5(2):195-201

Department of Medical Oncology, Josephine Nefkens Institute Be414, Erasmus MC, P.O. Box 1738, 3000 DR Rotterdam, the Netherlands.

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February 2007

BRCA1 mutation analysis of 41 human breast cancer cell lines reveals three new deleterious mutants.

Cancer Res 2006 Jan;66(1):41-5

Department of Medical Oncology, Josephine Nefkens Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.

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January 2006

Representational difference analysis as a tool in the search for new tumor suppressor genes.

Methods Mol Med 2005 ;103:143-59

Department of Medical Oncology, Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands.

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July 2005