Publications by authors named "Antoine Italiano"

100Publications

Novel Therapeutic Insights in Dedifferentiated Liposarcoma: A Role for FGFR and MDM2 Dual Targeting.

Cancers (Basel) 2020 Oct 20;12(10). Epub 2020 Oct 20.

Institute for Research on Cancer and Aging, Nice (IRCAN), Institut National de la Santé et de la Recherche Médicale (INSERM) U1081, Centre National de la Recherche Scientifique (CNRS) UMR7284, Université Côte d'Azur, 06107 Nice, France.

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http://dx.doi.org/10.3390/cancers12103058DOI Listing
October 2020

Impact of CT-based body composition parameters at baseline, their early changes and response in metastatic cancer patients treated with immune checkpoint inhibitors.

Eur J Radiol 2020 Oct 10;133:109340. Epub 2020 Oct 10.

Early Phase Trials Unit, Institut Bergonié, F-33000 Bordeaux, France; Department of Medical Oncology, Institut Bergonié, F-33000 Bordeaux, France.

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http://dx.doi.org/10.1016/j.ejrad.2020.109340DOI Listing
October 2020

Systematic review of sarcomas radiomics studies: Bridging the gap between concepts and clinical applications?

Eur J Radiol 2020 Sep 12;132:109283. Epub 2020 Sep 12.

Department of Radiology, Institut Bergonie, F-33000, Bordeaux, France.

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http://dx.doi.org/10.1016/j.ejrad.2020.109283DOI Listing
September 2020

Intensity harmonization techniques influence radiomics features and radiomics-based predictions in sarcoma patients.

Sci Rep 2020 Sep 23;10(1):15496. Epub 2020 Sep 23.

Modelisation in Oncology (MOnc) Team, INRIA Bordeaux-Sud-Ouest, CNRS UMR 5251, Université de Bordeaux, 33405, Talence, France.

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http://dx.doi.org/10.1038/s41598-020-72535-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511974PMC
September 2020

Combined PARP Inhibition and Immune Checkpoint Therapy in Solid Tumors.

Cancers (Basel) 2020 Jun 9;12(6). Epub 2020 Jun 9.

Department of Medical Oncology, Institut Bergonié, 33000 Bordeaux, France.

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http://dx.doi.org/10.3390/cancers12061502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352466PMC
June 2020

PD1/PD-L1 targeting in advanced soft-tissue sarcomas: a pooled analysis of phase II trials.

J Hematol Oncol 2020 05 19;13(1):55. Epub 2020 May 19.

Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1186/s13045-020-00891-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236113PMC
May 2020

Targeting epigenetics in sarcomas through EZH2 inhibition.

Authors:
Antoine Italiano

J Hematol Oncol 2020 04 7;13(1):33. Epub 2020 Apr 7.

Institut Bergonié, Early Phase Trial and Sarcoma Units, 229 cours de l'Argonne, 33076, Bordeaux, CEDEX, France.

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http://dx.doi.org/10.1186/s13045-020-00868-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140314PMC
April 2020

Can radiomics improve the prediction of metastatic relapse of myxoid/round cell liposarcomas?

Eur Radiol 2020 May 17;30(5):2413-2424. Epub 2020 Jan 17.

Department of Radiology, Institut Bergonie, F-33000, Bordeaux, France.

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http://dx.doi.org/10.1007/s00330-019-06562-5DOI Listing
May 2020

High-Grade Soft-Tissue Sarcomas: Can Optimizing Dynamic Contrast-Enhanced MRI Postprocessing Improve Prognostic Radiomics Models?

J Magn Reson Imaging 2020 07 10;52(1):282-297. Epub 2020 Jan 10.

Department of Radiology, Institut Bergonie, Bordeaux, France.

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http://dx.doi.org/10.1002/jmri.27040DOI Listing
July 2020

A new standard of care for patients with high-risk rhabdomyosarcoma?

Authors:
Antoine Italiano

Lancet Oncol 2020 01;21(1):e2

Institut Bergonié, Early Phase Trials and Sarcoma Units, 33000 Bordeaux, France; Faculty of Medicine, University of Bordeaux, Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(19)30784-3DOI Listing
January 2020

Pazopanib for progressive desmoid tumours: children, persistant effects, and cost - Author's reply.

Authors:
Antoine Italiano

Lancet Oncol 2019 10 30;20(10):e556. Epub 2019 Sep 30.

Department of Medicine, Institut Bergonié, Early Phase Trials and Sarcoma Units, 33000 Bordeaux, France; University of Bordeaux, Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(19)30575-3DOI Listing
October 2019

Abnormal vascularization of soft-tissue sarcomas on conventional MRI: Diagnostic and prognostic values.

Eur J Radiol 2019 Aug 11;117:112-119. Epub 2019 Jun 11.

Department of Radiology, Institut Bergonié, Comprehensive Cancer Center, F-33076, Bordeaux, France; University of Bordeaux, F-33000, Bordeaux, France; INSERM U1218, Action, Institut Bergonié, Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejrad.2019.06.007DOI Listing
August 2019

Olaratumab failure in sarcomas: what are the lessons learned?

Authors:
Antoine Italiano

Eur J Cancer 2019 08 27;117:69-70. Epub 2019 Jun 27.

Institut Bergonié, Early Phase Trials and Sarcoma Units, Bordeaux, France; University of Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.04.030DOI Listing
August 2019

Sarcoidosis-like reaction in metastatic triple negative breast cancer treated by anti-PD-L1.

Breast J 2019 09 4;25(5):971-973. Epub 2019 Jun 4.

Department of Medical Oncology, Institut Bergonié, Comprehensive Cancer Centre Bordeaux, Bordeaux, France.

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http://dx.doi.org/10.1111/tbj.13386DOI Listing
September 2019

Immune-checkpoint inhibitors and candidate surrogate endpoints for overall survival across tumour types: A systematic literature review.

Crit Rev Oncol Hematol 2019 May 1;137:35-42. Epub 2019 Mar 1.

Biostatistic Team, Bordeaux Population Health Center, ISPED, Centre INSERM U1219, INSERM, Bordeaux, France; Epicene Team (Cancer & Environnement), Bordeaux Population Health Center, ISPED, Centre INSERM U1219, INSERM, Bordeaux, France.

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http://dx.doi.org/10.1016/j.critrevonc.2019.02.013DOI Listing
May 2019

Influence of temporal parameters of DCE-MRI on the quantification of heterogeneity in tumor vascularization.

J Magn Reson Imaging 2019 12 13;50(6):1773-1788. Epub 2019 Apr 13.

Department of Radiology, Institut Bergonié, Comprehensive Cancer Center, Bordeaux, France.

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http://dx.doi.org/10.1002/jmri.26753DOI Listing
December 2019

Soft-Tissue Sarcomas: Assessment of MRI Features Correlating with Histologic Grade and Patient Outcome.

Radiology 2019 06 9;291(3):710-721. Epub 2019 Apr 9.

From the Departments of Diagnostic and Interventional Radiology (A.C., P.J.M., X.B., M.K.), Oncologic Surgery (E.S.), Clinical Epidemiology Research (V.B.), Medical Oncology (A.I.), and Pathology (F.L.L.), Bergonié Institute, Regional Comprehensive Cancer Center, Bordeaux, France; National Institute for Research in Digital Sciences (INRIA) Bordeaux-Sud-Ouest, Modeling in Oncology Team, National Center for Scientific Research (CNRS) Multidisciplinary Research Unit 5251, Talence, France (A.C.); and University of Bordeaux, Bordeaux, France (A.C., A.I., F.L.L.).

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http://dx.doi.org/10.1148/radiol.2019181659DOI Listing
June 2019

Distal extremities soft tissue sarcomas: Are they so different from other limb localizations?

J Surg Oncol 2019 Mar 4;119(4):479-488. Epub 2019 Jan 4.

Faculté de Médecine de la Timone, Génétique Médicale et génomique fonctionnelle, UMR S910 Inserm, Université Aix-Marseille 2, Marseille, France.

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http://dx.doi.org/10.1002/jso.25359DOI Listing
March 2019

T -based MRI Delta-radiomics improve response prediction in soft-tissue sarcomas treated by neoadjuvant chemotherapy.

J Magn Reson Imaging 2019 08 19;50(2):497-510. Epub 2018 Dec 19.

University of Bordeaux, IMB, UMR CNRS 5251, INRIA Project team Monc, Talence, France.

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http://doi.wiley.com/10.1002/jmri.26589
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http://dx.doi.org/10.1002/jmri.26589DOI Listing
August 2019

Is There Value in Molecular Profiling of Soft-Tissue Sarcoma?

Authors:
Antoine Italiano

Curr Treat Options Oncol 2018 12 7;19(12):78. Epub 2018 Dec 7.

Department of Medical Oncology, Institut Bergonié, 229 Cours de L'Argonne, 33076, Bordeaux, France.

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http://dx.doi.org/10.1007/s11864-018-0589-yDOI Listing
December 2018

Systemic Anti-Cancer Therapy in Synovial Sarcoma: A Systematic Review.

Cancers (Basel) 2018 Nov 1;10(11). Epub 2018 Nov 1.

Division of Medical Oncology, Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://www.mdpi.com/2072-6694/10/11/417
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http://dx.doi.org/10.3390/cancers10110417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267101PMC
November 2018

Molecular determinants of acquired resistance to BRAF inhibition in human lung cancer.

Lung Cancer 2018 12 12;126:227-229. Epub 2018 Oct 12.

Inserm U1218, Institut Bergonié, 229 Cours de l'Argonne, 33076 Bordeaux, France; Early Phase Trials Unit, Institut Bergonié, 229 Cours de l'Argonne, 33076 Bordeaux, France; University of Bordeaux, Bordeaux, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01695002183059
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http://dx.doi.org/10.1016/j.lungcan.2018.10.013DOI Listing
December 2018

Patterns of Care and Outcome Radiation-Induced Soft Tissue Sarcomas.

Int J Radiat Oncol Biol Phys 2019 02 5;103(2):449-452. Epub 2018 Oct 5.

Department of Radiation Oncology, Sorbonne University, HU La Pitié Salpêtrière Charles Foix, Assistance-Publique des Hôpitaux de Paris, Paris, France.

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https://linkinghub.elsevier.com/retrieve/pii/S03603016183380
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http://dx.doi.org/10.1016/j.ijrobp.2018.09.028DOI Listing
February 2019

Trends in Modern Phase 1 Oncology Trials.

Authors:
Antoine Italiano

N Engl J Med 2018 09;379(12):1189

Institut Bergonié, Bordeaux, France

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http://dx.doi.org/10.1056/NEJMc1808907DOI Listing
September 2018

High-grade soft-tissue sarcoma: optimizing injection improves MRI evaluation of tumor response.

Eur Radiol 2019 Feb 23;29(2):545-555. Epub 2018 Jul 23.

Department of Diagnostic and Interventional Radiology, Institut Bergonie, Comprehensive Cancer Center, 229 cours de l'Argonne, F-33000, Bordeaux, France.

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http://dx.doi.org/10.1007/s00330-018-5635-4DOI Listing
February 2019

Efficacy and safety of regorafenib compared to placebo and to post-cross-over regorafenib in advanced non-adipocytic soft tissue sarcoma.

Eur J Cancer 2018 08 11;99:28-36. Epub 2018 Jun 11.

Department of Clinical Research and Innovation, Centre Oscar Lambret, 3 rue Combemale, 59000 Lille, France; Paris-Saclay University, Univ. Paris-Sud, CESP, INSERM, Gustave Roussy, 94805 Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2018.05.008DOI Listing
August 2018

Future Prospects for PD-1 Targeting, Macrophage Infiltration, and IDO Pathway Activation in Patients With Sarcomas-Reply.

Authors:
Antoine Italiano

JAMA Oncol 2018 08;4(8):1134-1135

Department of Medical Oncology, Institut Bergonié, Bordeaux, France.

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http://dx.doi.org/10.1001/jamaoncol.2018.0895DOI Listing
August 2018

Encouraging Trends in Modern Phase 1 Oncology Trials.

N Engl J Med 2018 Jun;378(23):2242-2243

Institut Bergonié, Bordeaux, France

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http://dx.doi.org/10.1056/NEJMc1803837DOI Listing
June 2018

Meta-analyses evaluating surrogate endpoints for overall survival in cancer randomized trials: A critical review.

Crit Rev Oncol Hematol 2018 Mar 23;123:21-41. Epub 2017 Nov 23.

Clinical and Epidemiological Research Unit, Institut Bergonié, Comprehensive Cancer Center, 229 Cours de l'Argonne, 33000 Bordeaux, France; INSERM CIC-EC 14.01 (Clinical Epidemiology), Bordeaux, France; INSERM, ISPED, Centre INSERM U1219 Bordeaux Population Health Center, Epicene Team, 146 Rue Léo Saignat, 33076 Bordeaux, France; University of Bordeaux, ISPED, Centre INSERM U1219 Bordeaux Population Health, Epicene Team, 146 Rue Léo Saignat, 33076 Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2017.11.014DOI Listing
March 2018

Newer therapeutic strategies for soft-tissue sarcomas.

Pharmacol Ther 2018 08 24;188:118-123. Epub 2018 Feb 24.

Early Phase Trials and Sarcoma Units, Institut Bergonié, 229 Cours de l'Argonne, 33000 Bordeaux, France; University of Bordeaux, Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2018.02.014DOI Listing
August 2018

PD-1 inhibition in sarcoma still needs investigation.

Lancet Oncol 2018 01;19(1):e6

Early Phase Trial and Sarcoma Units, Institut Bergonié, 33000 Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(17)30921-XDOI Listing
January 2018

Biology and Management of Undifferentiated Pleomorphic Sarcoma, Myxofibrosarcoma, and Malignant Peripheral Nerve Sheath Tumors: State of the Art and Perspectives.

J Clin Oncol 2018 01 8;36(2):160-167. Epub 2017 Dec 8.

Brigitte C. Widemann, National Cancer Institute, Bethesda, MD; and Antoine Italiano, Institut Bergonié and University of Bordeaux, Bordeaux, France.

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http://dx.doi.org/10.1200/JCO.2017.75.3467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759316PMC
January 2018

MDM2 antagonists synergize with PI3K/mTOR inhibition in well-differentiated/dedifferentiated liposarcomas.

Oncotarget 2017 Aug 17;8(33):53968-53977. Epub 2017 Mar 17.

Institut National de la Santé et de la Recherche Medicale, Institut Bergonié, Bordeaux, France.

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http://www.oncotarget.com/fulltext/16345
Publisher Site
http://dx.doi.org/10.18632/oncotarget.16345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589555PMC
August 2017