Antoine Italiano

Antoine Italiano

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Antoine Italiano

Publications by authors named "Antoine Italiano"

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Pazopanib for progressive desmoid tumours: children, persistant effects, and cost - Author's reply.

Authors:
Antoine Italiano

Lancet Oncol 2019 Oct 30;20(10):e556. Epub 2019 Sep 30.

Department of Medicine, Institut Bergonié, Early Phase Trials and Sarcoma Units, 33000 Bordeaux, France; University of Bordeaux, Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(19)30575-3DOI Listing
October 2019

Sarcoidosis-like reaction in metastatic triple negative breast cancer treated by anti-PD-L1.

Breast J 2019 Sep 4;25(5):971-973. Epub 2019 Jun 4.

Department of Medical Oncology, Institut Bergonié, Comprehensive Cancer Centre Bordeaux, Bordeaux, France.

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http://dx.doi.org/10.1111/tbj.13386DOI Listing
September 2019

T -based MRI Delta-radiomics improve response prediction in soft-tissue sarcomas treated by neoadjuvant chemotherapy.

J Magn Reson Imaging 2019 Aug 19;50(2):497-510. Epub 2018 Dec 19.

University of Bordeaux, IMB, UMR CNRS 5251, INRIA Project team Monc, Talence, France.

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http://doi.wiley.com/10.1002/jmri.26589
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http://dx.doi.org/10.1002/jmri.26589DOI Listing
August 2019

Olaratumab failure in sarcomas: what are the lessons learned?

Authors:
Antoine Italiano

Eur J Cancer 2019 Aug 27;117:69-70. Epub 2019 Jun 27.

Institut Bergonié, Early Phase Trials and Sarcoma Units, Bordeaux, France; University of Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.04.030DOI Listing
August 2019

Abnormal vascularization of soft-tissue sarcomas on conventional MRI: Diagnostic and prognostic values.

Eur J Radiol 2019 Aug 11;117:112-119. Epub 2019 Jun 11.

Department of Radiology, Institut Bergonié, Comprehensive Cancer Center, F-33076, Bordeaux, France; University of Bordeaux, F-33000, Bordeaux, France; INSERM U1218, Action, Institut Bergonié, Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejrad.2019.06.007DOI Listing
August 2019

Soft-Tissue Sarcomas: Assessment of MRI Features Correlating with Histologic Grade and Patient Outcome.

Radiology 2019 Jun 9;291(3):710-721. Epub 2019 Apr 9.

From the Departments of Diagnostic and Interventional Radiology (A.C., P.J.M., X.B., M.K.), Oncologic Surgery (E.S.), Clinical Epidemiology Research (V.B.), Medical Oncology (A.I.), and Pathology (F.L.L.), Bergonié Institute, Regional Comprehensive Cancer Center, Bordeaux, France; National Institute for Research in Digital Sciences (INRIA) Bordeaux-Sud-Ouest, Modeling in Oncology Team, National Center for Scientific Research (CNRS) Multidisciplinary Research Unit 5251, Talence, France (A.C.); and University of Bordeaux, Bordeaux, France (A.C., A.I., F.L.L.).

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http://dx.doi.org/10.1148/radiol.2019181659DOI Listing
June 2019

Immune-checkpoint inhibitors and candidate surrogate endpoints for overall survival across tumour types: A systematic literature review.

Crit Rev Oncol Hematol 2019 May 1;137:35-42. Epub 2019 Mar 1.

Biostatistic Team, Bordeaux Population Health Center, ISPED, Centre INSERM U1219, INSERM, Bordeaux, France; Epicene Team (Cancer & Environnement), Bordeaux Population Health Center, ISPED, Centre INSERM U1219, INSERM, Bordeaux, France.

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http://dx.doi.org/10.1016/j.critrevonc.2019.02.013DOI Listing
May 2019

Influence of temporal parameters of DCE-MRI on the quantification of heterogeneity in tumor vascularization.

J Magn Reson Imaging 2019 Apr 13. Epub 2019 Apr 13.

Department of Radiology, Institut Bergonié, Comprehensive Cancer Center, Bordeaux, France.

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http://dx.doi.org/10.1002/jmri.26753DOI Listing
April 2019

Distal extremities soft tissue sarcomas: Are they so different from other limb localizations?

J Surg Oncol 2019 Mar 4;119(4):479-488. Epub 2019 Jan 4.

Faculté de Médecine de la Timone, Génétique Médicale et génomique fonctionnelle, UMR S910 Inserm, Université Aix-Marseille 2, Marseille, France.

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http://dx.doi.org/10.1002/jso.25359DOI Listing
March 2019

High-grade soft-tissue sarcoma: optimizing injection improves MRI evaluation of tumor response.

Eur Radiol 2019 Feb 23;29(2):545-555. Epub 2018 Jul 23.

Department of Diagnostic and Interventional Radiology, Institut Bergonie, Comprehensive Cancer Center, 229 cours de l'Argonne, F-33000, Bordeaux, France.

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http://dx.doi.org/10.1007/s00330-018-5635-4DOI Listing
February 2019

Patterns of Care and Outcome Radiation-Induced Soft Tissue Sarcomas.

Int J Radiat Oncol Biol Phys 2019 02 5;103(2):449-452. Epub 2018 Oct 5.

Department of Radiation Oncology, Sorbonne University, HU La Pitié Salpêtrière Charles Foix, Assistance-Publique des Hôpitaux de Paris, Paris, France.

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https://linkinghub.elsevier.com/retrieve/pii/S03603016183380
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http://dx.doi.org/10.1016/j.ijrobp.2018.09.028DOI Listing
February 2019

Molecular determinants of acquired resistance to BRAF inhibition in human lung cancer.

Lung Cancer 2018 12 12;126:227-229. Epub 2018 Oct 12.

Inserm U1218, Institut Bergonié, 229 Cours de l'Argonne, 33076 Bordeaux, France; Early Phase Trials Unit, Institut Bergonié, 229 Cours de l'Argonne, 33076 Bordeaux, France; University of Bordeaux, Bordeaux, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01695002183059
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http://dx.doi.org/10.1016/j.lungcan.2018.10.013DOI Listing
December 2018

Is There Value in Molecular Profiling of Soft-Tissue Sarcoma?

Authors:
Antoine Italiano

Curr Treat Options Oncol 2018 12 7;19(12):78. Epub 2018 Dec 7.

Department of Medical Oncology, Institut Bergonié, 229 Cours de L'Argonne, 33076, Bordeaux, France.

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http://dx.doi.org/10.1007/s11864-018-0589-yDOI Listing
December 2018

Systemic Anti-Cancer Therapy in Synovial Sarcoma: A Systematic Review.

Cancers (Basel) 2018 Nov 1;10(11). Epub 2018 Nov 1.

Division of Medical Oncology, Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://www.mdpi.com/2072-6694/10/11/417
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http://dx.doi.org/10.3390/cancers10110417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267101PMC
November 2018

Trends in Modern Phase 1 Oncology Trials.

Authors:
Antoine Italiano

N Engl J Med 2018 09;379(12):1189

Institut Bergonié, Bordeaux, France

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http://dx.doi.org/10.1056/NEJMc1808907DOI Listing
September 2018

Newer therapeutic strategies for soft-tissue sarcomas.

Pharmacol Ther 2018 08 24;188:118-123. Epub 2018 Feb 24.

Early Phase Trials and Sarcoma Units, Institut Bergonié, 229 Cours de l'Argonne, 33000 Bordeaux, France; University of Bordeaux, Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2018.02.014DOI Listing
August 2018

Future Prospects for PD-1 Targeting, Macrophage Infiltration, and IDO Pathway Activation in Patients With Sarcomas-Reply.

Authors:
Antoine Italiano

JAMA Oncol 2018 08;4(8):1134-1135

Department of Medical Oncology, Institut Bergonié, Bordeaux, France.

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http://dx.doi.org/10.1001/jamaoncol.2018.0895DOI Listing
August 2018

Efficacy and safety of regorafenib compared to placebo and to post-cross-over regorafenib in advanced non-adipocytic soft tissue sarcoma.

Eur J Cancer 2018 08 11;99:28-36. Epub 2018 Jun 11.

Department of Clinical Research and Innovation, Centre Oscar Lambret, 3 rue Combemale, 59000 Lille, France; Paris-Saclay University, Univ. Paris-Sud, CESP, INSERM, Gustave Roussy, 94805 Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2018.05.008DOI Listing
August 2018

Encouraging Trends in Modern Phase 1 Oncology Trials.

N Engl J Med 2018 Jun;378(23):2242-2243

Institut Bergonié, Bordeaux, France

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http://dx.doi.org/10.1056/NEJMc1803837DOI Listing
June 2018

Meta-analyses evaluating surrogate endpoints for overall survival in cancer randomized trials: A critical review.

Crit Rev Oncol Hematol 2018 Mar 23;123:21-41. Epub 2017 Nov 23.

Clinical and Epidemiological Research Unit, Institut Bergonié, Comprehensive Cancer Center, 229 Cours de l'Argonne, 33000 Bordeaux, France; INSERM CIC-EC 14.01 (Clinical Epidemiology), Bordeaux, France; INSERM, ISPED, Centre INSERM U1219 Bordeaux Population Health Center, Epicene Team, 146 Rue Léo Saignat, 33076 Bordeaux, France; University of Bordeaux, ISPED, Centre INSERM U1219 Bordeaux Population Health, Epicene Team, 146 Rue Léo Saignat, 33076 Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2017.11.014DOI Listing
March 2018

Biology and Management of Undifferentiated Pleomorphic Sarcoma, Myxofibrosarcoma, and Malignant Peripheral Nerve Sheath Tumors: State of the Art and Perspectives.

J Clin Oncol 2018 01 8;36(2):160-167. Epub 2017 Dec 8.

Brigitte C. Widemann, National Cancer Institute, Bethesda, MD; and Antoine Italiano, Institut Bergonié and University of Bordeaux, Bordeaux, France.

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http://dx.doi.org/10.1200/JCO.2017.75.3467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759316PMC
January 2018

PD-1 inhibition in sarcoma still needs investigation.

Lancet Oncol 2018 01;19(1):e6

Early Phase Trial and Sarcoma Units, Institut Bergonié, 33000 Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(17)30921-XDOI Listing
January 2018

What are the challenges in 2016 regarding resistance to tyrosine kinase inhibitors in chronic myeloid leukemia and cancer?

Hematol Oncol 2017 Dec 19;35(4):420-423. Epub 2016 Jul 19.

Laboratory of Mammary and Leukemic Oncogenesis: Genetic Diversity and Resistance to Treatment, ACTION, INSERM U1218, University of Bordeaux, Bordeaux, Gironde, France.

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http://dx.doi.org/10.1002/hon.2329DOI Listing
December 2017

Clinical activity of eribulin in advanced desmoplastic small round-cell tumor.

Anticancer Drugs 2017 10;28(9):1053-1055

Departments of aMedical Oncology bRadiology cPathology dSurgery, Institut Bergonie, Bordeaux, France.

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http://Insights.ovid.com/crossref?an=00001813-201710000-0001
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http://dx.doi.org/10.1097/CAD.0000000000000536DOI Listing
October 2017

CSF-1R Inhibitor Development: Current Clinical Status.

Curr Oncol Rep 2017 Sep 5;19(11):70. Epub 2017 Sep 5.

Early Phase Trials Unit, Institut Bergonié, 229 Cours de l'Argonne, 33000, Bordeaux, France.

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http://dx.doi.org/10.1007/s11912-017-0634-1DOI Listing
September 2017

Genetic determinants of response to fibroblast growth factor receptor inhibitors in solid tumours.

Eur J Cancer 2017 08 15;81:102-105. Epub 2017 Jun 15.

University of Bordeaux, Bordeaux, France; Early Phase Trials Unit, Institut Bergonié, Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.04.011DOI Listing
August 2017

Olaratumab for soft tissue sarcoma.

Expert Opin Biol Ther 2017 08 10;17(8):1019-1025. Epub 2017 Jul 10.

a Early Phase Trials and Sarcoma Units , Institut Bergonié , Bordeaux , France.

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https://www.tandfonline.com/doi/full/10.1080/14712598.2017.1
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http://dx.doi.org/10.1080/14712598.2017.1339031DOI Listing
August 2017

MDM2 antagonists synergize with PI3K/mTOR inhibition in well-differentiated/dedifferentiated liposarcomas.

Oncotarget 2017 Aug 17;8(33):53968-53977. Epub 2017 Mar 17.

Institut National de la Santé et de la Recherche Medicale, Institut Bergonié, Bordeaux, France.

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http://www.oncotarget.com/fulltext/16345
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http://dx.doi.org/10.18632/oncotarget.16345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589555PMC
August 2017

Clinical efficacy of eribulin mesylate for the treatment of metastatic soft tissue sarcoma.

Expert Opin Pharmacother 2017 Jun;18(8):819-824

a Early Phase Trials and Sarcoma Units , Institut Bergonié , Bordeaux , France.

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http://dx.doi.org/10.1080/14656566.2017.1326908DOI Listing
June 2017

Combined targeting of MDM2 and CDK4 is synergistic in dedifferentiated liposarcomas.

J Hematol Oncol 2017 06 19;10(1):123. Epub 2017 Jun 19.

Institut National de la Santé et de la Recherche Medicale (INSERM) U1218, Institut Bergonié, 229 cours de l'Argonne, 33076, Bordeaux cedex, France.

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http://dx.doi.org/10.1186/s13045-017-0482-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477309PMC
June 2017

Ten-Year Progression-Free and Overall Survival in Patients With Unresectable or Metastatic GI Stromal Tumors: Long-Term Analysis of the European Organisation for Research and Treatment of Cancer, Italian Sarcoma Group, and Australasian Gastrointestinal Trials Group Intergroup Phase III Randomized Trial on Imatinib at Two Dose Levels.

J Clin Oncol 2017 May 31;35(15):1713-1720. Epub 2017 Mar 31.

Paolo G. Casali, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale Tumori and University of Milan; Elena Fumagalli and Alessandro Gronchi, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale Tumori, Milano, Italy; John Zalcberg, Peter MacCallum Cancer Institute, East Melbourne, Victoria; Dusan Kotasek, Adelaide Cancer Centre, Kurralta Park and University of Adelaide, South Australia, Australia; Axel Le Cesne, Gustave Roussy, Villejuif; Jean-Yves Blay, NetSARC and Site de Recherche Intégrée sur le Cancer de Lyon, Centre Leon Berard, Lyon; Antoine Italiano, Institut Bergonie, Bordeaux, France; Peter Reichardt, HELIOS Klinikum Berlin-Buch, Berlin; Lars H. Lindner, Klinikum der Universitaet München, München; Viktor Grünwald, School Hannover, Hannover, Germany; Ian R. Judson and Winette van der Graaf, Royal Marsden Hospital, London, United Kingdom; Patrick Schöffski, Universitaire Ziekenhuizen Leuven, Campus Gasthuisberg, Leuven; Saskia Litière and Sandrine Marreaud, European Organisation for Research and Treatment of Cancer Headquarters, Brussels, Belgium; Serge Leyvraz, University Hospital, Lausanne, Switzerland; Antonio Lopez Pousa, Hospital De La Santa Creu I Sant Pau, Barcelona, Spain; Stefan Sleijfer and Jaap Verweij, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam; Jan M. Kerst, The Netherlands Cancer Institute, Amsterdam; Pancras Hogendoorn, Leiden University Medical Center, Leiden; Winette van der Graaf, Radboud University, Medical Center Nijmegen, the Netherlands; and Piotr Rutkowski, Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Warsaw, Poland.

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http://ascopubs.org/doi/10.1200/JCO.2016.71.0228
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http://dx.doi.org/10.1200/JCO.2016.71.0228DOI Listing
May 2017

Phase-II trials in osteosarcoma recurrences: A systematic review of past experience.

Eur J Cancer 2017 04 20;75:98-108. Epub 2017 Feb 20.

Department of Oncology for Child and Adolescents, Institut Gustave Roussy, 114 rue Edouard Vaillant, 94805 Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.01.005DOI Listing
April 2017

Activity of trabectedin and the PARP inhibitor rucaparib in soft-tissue sarcomas.

J Hematol Oncol 2017 04 11;10(1):84. Epub 2017 Apr 11.

INSERM ACTION U1218, Institut Bergonié, 229 cours de l'Argonne, 33076, Bordeaux cedex, France.

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http://dx.doi.org/10.1186/s13045-017-0451-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387279PMC
April 2017

PICASSO III: A Phase III, Placebo-Controlled Study of Doxorubicin With or Without Palifosfamide in Patients With Metastatic Soft Tissue Sarcoma.

J Clin Oncol 2016 11 30;34(32):3898-3905. Epub 2016 Sep 30.

Christopher W. Ryan, Oregon Health & Science University, Portland, OR; Ofer Merimsky, Sackler School of Medicine, Tel-Aviv, Israel; Mark Agulnik, Northwestern University, Chicago, IL; Jean-Yves Blay, Centre Léon Bérard, Lyon; Antoine Italiano, Institut Bergonié, Bordeaux, France; Scott M. Schuetze, University of Michigan, Ann Arbor, MI; Brian A. Van Tine, Washington University in St Louis, St Louis, MO; Robin L. Jones and Ian R. Judson, The Royal Marsden Hospital, London, United Kingdom; Anthony D. Elias, University of Colorado-Denver, Aurora, CO; Edwin Choy, Massachusetts General Hospital; Jill Y. Buck and Francois Lebel, ZIOPHARM Oncology, Boston, MA; Thierry Alcindor, McGill University Health Center, Montreal, Quebec, Canada; Vicki L. Keedy, Vanderbilt University Medical Center, Nashville, TN; Damon R. Reed, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; Robert N. Taub, Columbia University Medical Center; Jonathan J. Lewis, Samus Therapeutics and Molecular Ninja Group; Robert G. Maki, Mount Sinai School of Medicine, New York, NY; Xavier Garcia del Muro, Institut Català d'Oncologia L'Hospitalet, Barcelona, Spain; and Patrick Schöffski, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1200/JCO.2016.67.6684DOI Listing
November 2016

Trabectedin as a chemotherapy option for patients with BRCA deficiency.

Cancer Treat Rev 2016 Nov 15;50:175-182. Epub 2016 Sep 15.

Department of Oncology, IRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Via La Masa, 19, 20156 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2016.09.009DOI Listing
November 2016

Challenging a dogma: co-mutations exist in MAPK pathway genes in colorectal cancer.

Virchows Arch 2016 Oct 11;469(4):459-64. Epub 2016 Jul 11.

Molecular Pathology Unit, Institut Bergonié, 229 Cours de L'Argonne, 33076, Bordeaux, France.

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http://dx.doi.org/10.1007/s00428-016-1991-0DOI Listing
October 2016

PRognostic factor of Early Death In phase II Trials or the end of 'sufficient life expectancy' as an inclusion criterion? (PREDIT model).

BMC Cancer 2016 10 4;16(1):768. Epub 2016 Oct 4.

Department of Medical Oncology, Institut Bergonié, Comprehensive Cancer Centre Bordeaux, 229 cours de l'Argonne, 33076, Bordeaux, France.

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http://dx.doi.org/10.1186/s12885-016-2819-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050995PMC
October 2016

Role of the EZH2 histone methyltransferase as a therapeutic target in cancer.

Authors:
Antoine Italiano

Pharmacol Ther 2016 09 11;165:26-31. Epub 2016 May 11.

Early Phase Trials and Sarcoma Units, Institut Bergonié, 229 cours de l'Argonne, 33000 Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2016.05.003DOI Listing
September 2016

Molecular Pathways: Immune Checkpoint Antibodies and their Toxicities.

Clin Cancer Res 2016 Sep 19;22(18):4550-5. Epub 2016 Jul 19.

Early Phase Trials Unit, Institut Bergonié, Bordeaux, France. Department of Medicine, Institut Bergonié, Bordeaux, France.

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http://clincancerres.aacrjournals.org/content/clincanres/ear
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http://clincancerres.aacrjournals.org/content/22/18/4550.ful
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http://dx.doi.org/10.1158/1078-0432.CCR-15-2569DOI Listing
September 2016

Clinical effect of molecular methods in sarcoma diagnosis (GENSARC): a prospective, multicentre, observational study.

Lancet Oncol 2016 Apr 10;17(4):532-538. Epub 2016 Mar 10.

Laboratory of Solid Tumor Genetics, Nice University Hospital, Nice, France; Institute for Research on Cancer and Aging of Nice (IRCAN), Faculty of Medicine, University of Nice-Sophia-Antipolis, CNRS, Nice, France.

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http://dx.doi.org/10.1016/S1470-2045(15)00583-5DOI Listing
April 2016

Time to Definitive Failure to the First Tyrosine Kinase Inhibitor in Localized GI Stromal Tumors Treated With Imatinib As an Adjuvant: A European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Intergroup Randomized Trial in Collaboration With the Australasian Gastro-Intestinal Trials Group, UNICANCER, French Sarcoma Group, Italian Sarcoma Group, and Spanish Group for Research on Sarcomas.

J Clin Oncol 2015 Dec 16;33(36):4276-83. Epub 2015 Nov 16.

Paolo G. Casali, Elena Fumagalli, and Alessandro Gronchi, Fondazione Istituto di Recovero e Cura a Carattere Scientifico Istituto Nazionale Tumori, Milano; Angelo P. Dei Tos, Azienda Unità Locale Socio Sanitaria 9 Treviso, Treviso, Italy; Axel Le Cesne, Gustave Roussy, Villejuif; Antoine Italiano, Institut Bergonie, Bordeaux; Antoine Adenis, Centre Oscar Lambret, Lille; Florence Duffaud, Hôpital de La Timone, Aix-Marseille Université, Marseille; Jean-Yves Blay, Centre Leon Berard, Lyon, France; Andres Poveda Velasco, Instituto Valenciano de Oncologia, Valencia; Javier M. Broto, Hospital Universitari Son Espases, Palma de Mallorca, Spain; Dusan Kotasek, Adelaide Cancer Centre, Kurralta Park, and University of Adelaide, Adelaide, South Australia; David Goldstein, Prince of Wales Hospital, New South Wales, Sydney; John R. Zalcberg, Peter MacCallum Cancer Institute, East Melbourne, Victoria, Australia; Piotr Rutkowski, Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Warsaw, Poland; Peter Hohenberger, Mannheim University Medical Center, Mannheim; Jörg T. Hartmann, Christian-Albrechts University, Kiel, Germany; Ian R. Judson, Royal Marsden Hospital; Winette T.A. van der Graaf, The Institute of Cancer Research and the Royal Marsden NHS Foundation Trust, London, United Kingdom; Hans Gelderblom, Leiden University Medical Center, Leiden; Winette T.A. van der Graaf, Radboud University Medical Center, Nijmegen, the Netherlands; Saskia Litière, and Sandrine Marréaud, European Organisation for Research and Treatment of Cancer, Brussels, Belgium.

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http://jco.ascopubs.org/content/early/2015/11/16/JCO.2015.62
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2015.62.4304
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http://dx.doi.org/10.1200/JCO.2015.62.4304DOI Listing
December 2015

Clinical activity of regorafenib in -mutated gastrointestinal stromal tumor.

Future Sci OA 2015 Nov 1;1(4):FSO33. Epub 2015 Nov 1.

Department of Medical Oncology, Institut Bergonié, Bordeaux, France; Department of Medical Oncology, Institut Bergonié, Bordeaux, France.

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http://dx.doi.org/10.4155/fso.15.33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137998PMC
November 2015

PRIMA-1(MET) induces death in soft-tissue sarcomas cell independent of p53.

BMC Cancer 2015 Oct 13;15:684. Epub 2015 Oct 13.

National Institute of Health and Medical research, INSERM U916, Institut Bergonié, Bordeaux, France.

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http://dx.doi.org/10.1186/s12885-015-1667-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604610PMC
October 2015