Anthony V Moorman

Anthony V Moorman

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Anthony V Moorman

Anthony V Moorman

Publications by authors named "Anthony V Moorman"

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88Publications

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Long-term survival after childhood acute lymphoblastic leukaemia: population-based trends in cure and relapse by clinical characteristics.

Br J Haematol 2018 Sep 29;182(6):851-858. Epub 2018 May 29.

Clinical and Population Sciences Department, School of Medicine, University of Leeds, Leeds, UK.

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September 2018

Genotype-Specific Minimal Residual Disease Interpretation Improves Stratification in Pediatric Acute Lymphoblastic Leukemia.

J Clin Oncol 2018 Jan 13;36(1):34-43. Epub 2017 Nov 13.

David O'Connor, Jack Bartram, Sujith Samarasinghe, Ajay Vora, and Nick Goulden, Great Ormond Street Hospital; Rachael Hough, University College Hospital, London; Amir Enshaei, Christine J. Harrison, Claire Schwab, and Anthony V. Moorman, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne; Jeremy Hancock, North Bristol National Health Service Trust; John Moppett, Royal Hospital for Sick Children, Bristol; Ajay Vora, Sheffield Children's Hospital, Sheffield; Rachel Wade, Medical Research Council, University of Oxford, Oxford, United Kingdom; and Nick Goulden, Trapehade, Monferran-Plavès, France.

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January 2018

Time for ALL adults to catch up with the children.

Blood 2017 10;130(16):1781-1783

NEWCASTLE UNIVERSITY.

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October 2017

Characterisation of the genomic landscape of CRLF2-rearranged acute lymphoblastic leukemia.

Genes Chromosomes Cancer 2017 05 18;56(5):363-372. Epub 2017 Jan 18.

Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, UK.

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May 2017

Use of Minimal Residual Disease Assessment to Redefine Induction Failure in Pediatric Acute Lymphoblastic Leukemia.

J Clin Oncol 2017 Feb 3;35(6):660-667. Epub 2017 Jan 3.

David O'Connor, Ronald M.R. Tan, Jack Bartram, and Sujith Samarasinghe, Great Ormond Street Hospital for Children NHS Foundation Trust; Rachael Hough, University College London Hospitals NHS Foundation Trust, London; Anthony V. Moorman, Claire Schwab, and Christine J. Harrison, Newcastle University, Newcastle Upon Tyne; Rachel Wade, University of Oxford, Oxford; Jeremy Hancock, North Bristol NHS Trust; John Moppett, Royal Hospital for Children, Bristol; Ajay Vora and Katharine Patrick, Sheffield Children's NHS Foundation Trust, Sheffield, United Kingdom; and Nick Goulden, Trapehade, Monferran Plaves, France.

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February 2017

New and emerging prognostic and predictive genetic biomarkers in B-cell precursor acute lymphoblastic leukemia.

Haematologica 2016 Apr;101(4):407-16

Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, UK

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April 2016

A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia.

Blood 2014 Aug 23;124(9):1434-44. Epub 2014 Jun 23.

Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom;

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August 2014

Does TP53 guard ALL genomes?

Blood 2014 Jul;124(2):160-1

NEWCASTLE UNIVERSITY.

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July 2014

IGH@ translocations are prevalent in teenagers and young adults with acute lymphoblastic leukemia and are associated with a poor outcome.

J Clin Oncol 2014 May 7;32(14):1453-62. Epub 2014 Apr 7.

Lisa J. Russell, Amir Enshaei, Lisa Jones, Amy Erhorn, Dino Masic, Helen Bentley, Anthony V. Moorman, and Christine J. Harrison, Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne; Karl S. Laczko, Leica Microsystems, Gateshead; Adele K. Fielding, Royal Free and University College London Medical School; Anthony H. Goldstone, University College London Hospital; Nicholas Goulden, Great Ormond St Hospital, London; Christopher D. Mitchell, John Radcliffe Hospital; Rachel Wade, Clinical Trial Service Unit, University of Oxford, Oxford; and Ajay Vora, Sheffield Children's Hospital, Sheffield, United Kingdom.

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May 2014

Unravelling the prognostic effect of IKZF1 deletions and IGH@-CRLF2 in adult acute lymphoblastic leukaemia.

Pathology 2013 10;45(6):609-12

*Department of Haematology †PathWest Laboratory Medicine, Royal Perth Hospital, Perth ‡School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, WA, Australia §Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, UK.

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October 2013

Risk-directed treatment intensification significantly reduces the risk of relapse among children and adolescents with acute lymphoblastic leukemia and intrachromosomal amplification of chromosome 21: a comparison of the MRC ALL97/99 and UKALL2003 trials.

J Clin Oncol 2013 Sep 12;31(27):3389-96. Epub 2013 Aug 12.

Anthony V. Moorman, Hazel Robinson, Claire Schwab, and Christine J. Harrison, Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Newcastle University, Newcastle; Sue M. Richards, University of Oxford; Christopher D. Mitchell, John Radcliffe Hospital, Oxford; Jeremy Hancock, Bristol Genetics Laboratory, North Bristol National Health Service Trust, Bristol; Nicholas Goulden, Great Ormond Street Hospital, London; and Ajay Vora, Sheffield Children's Hospital, Sheffield, United Kingdom.

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September 2013

Genes commonly deleted in childhood B-cell precursor acute lymphoblastic leukemia: association with cytogenetics and clinical features.

Haematologica 2013 Jul 18;98(7):1081-8. Epub 2013 Mar 18.

Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, UK.

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July 2013

Abnormalities of the der(12)t(12;21) in ETV6-RUNX1 acute lymphoblastic leukemia.

Genes Chromosomes Cancer 2013 Feb 18;52(2):202-13. Epub 2012 Oct 18.

Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, UK.

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February 2013

IGH@ translocations, CRLF2 deregulation, and microdeletions in adolescents and adults with acute lymphoblastic leukemia.

J Clin Oncol 2012 Sep 30;30(25):3100-8. Epub 2012 Jul 30.

Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Level 5, Sir James Spence Institute, Royal Victoria Infirmary, Queen Victoria Rd, Newcastle-upon-Tyne, NE1 4LP, United Kingdom.

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September 2012

The clinical relevance of chromosomal and genomic abnormalities in B-cell precursor acute lymphoblastic leukaemia.

Blood Rev 2012 May 20;26(3):123-35. Epub 2012 Mar 20.

Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Newcastle University, United Kingdom.

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May 2012

Epigenetic inactivation of TWIST2 in acute lymphoblastic leukemia modulates proliferation, cell survival and chemosensitivity.

Haematologica 2012 Mar 4;97(3):371-8. Epub 2011 Nov 4.

Crucible Laboratory, Institute for Ageing and Health, Newcastle University, Newcastle-upon-Tyne, NE1 3BZ, UK.

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March 2012

Immunophenotype and cytogenetic characteristics in the relationship between birth weight and childhood leukemia.

Pediatr Blood Cancer 2012 Jan 16;58(1):7-11. Epub 2011 Jun 16.

Childhood Cancer Research Group, University of Oxford, Oxford, UK.

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January 2012

Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial.

Lancet 2010 Dec 3;376(9757):2009-17. Epub 2010 Dec 3.

Cancer Research UK Children's Cancer Group, School of Cancer and Enabling Sciences, University of Manchester, Manchester Academic Health Science Centre, Central Manchester University Hospitals Foundation Trust, Manchester, UK.

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December 2010

Cytogenetics of childhood acute myeloid leukemia: United Kingdom Medical Research Council Treatment trials AML 10 and 12.

J Clin Oncol 2010 Jun 3;28(16):2674-81. Epub 2010 May 3.

Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Newcastle University, Queen Victoria Road, Newcastle-upon-Tyne, UK.

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June 2010

A population-based cytogenetic study of adults with acute lymphoblastic leukemia.

Blood 2010 Jan 6;115(2):206-14. Epub 2009 Nov 6.

Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom.

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January 2010

Prognostic factor analysis of the survival of elderly patients with AML in the MRC AML11 and LRF AML14 trials.

Br J Haematol 2009 Jun 26;145(5):598-605. Epub 2009 Mar 26.

Birmingham Clinical Trials Unit, School of Cancer Sciences, Robert Aitken Institute, University of Birmingham, Edgbaston, Birmingham, UK.

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June 2009

Variable breakpoints target PAX5 in patients with dicentric chromosomes: a model for the basis of unbalanced translocations in cancer.

Proc Natl Acad Sci U S A 2008 Nov 28;105(44):17050-4. Epub 2008 Oct 28.

Cancer Genomics and Leukaemia Research Cytogenetics Groups, Cancer Sciences Division, University of Southampton, Southampton, SO16 6YD, United Kingdom.

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November 2008

Molecular cytogenetic characterization of TCF3 (E2A)/19p13.3 rearrangements in B-cell precursor acute lymphoblastic leukemia.

Genes Chromosomes Cancer 2007 May;46(5):478-86

Leukaemia Research Cytogenetics Group, Cancer Sciences Division, University of Southampton, Southampton, UK.

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May 2007

Intrachromosomal amplification of chromosome 21 (iAMP21) may arise from a breakage-fusion-bridge cycle.

Genes Chromosomes Cancer 2007 Apr;46(4):318-26

Leukaemia Research Cytogenetics Group, Cancer Sciences Division, University of Southampton, Southampton, UK.

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April 2007

Breakpoints of variant 9;22 translocations in chronic myeloid leukemia locate preferentially in the CG-richest regions of the genome.

Genes Chromosomes Cancer 2005 Aug;43(4):383-9

Wessex Regional Genetics Laboratory, Salisbury District Hospital, UK.

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August 2005

Outcome after first relapse in childhood acute lymphoblastic leukaemia - lessons from the United Kingdom R2 trial.

Br J Haematol 2005 Jul;130(1):67-75

Cancer Research UK Children's Cancer Group, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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July 2005

ETV6/RUNX1 fusion at diagnosis and relapse: some prognostic indications.

Genes Chromosomes Cancer 2005 May;43(1):54-71

LRF Cytogenetics Group, Cancer Sciences Division, University of Southampton, United Kingdom.

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May 2005

MLL translocations with concurrent 3' deletions: interpretation of FISH results.

Genes Chromosomes Cancer 2004 Nov;41(3):266-71

Leukaemia Research Fund Cytogenetics Group, Cancer Sciences Division, University of Southampton, Southampton, United Kingdom.

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November 2004

t(14;19)(q32;q13): a recurrent translocation in B-cell precursor acute lymphoblastic leukemia.

Genes Chromosomes Cancer 2004 Jan;39(1):88-92

Leukaemia Research Fund Cytogenetics Group, Cancer Sciences Division, University of Southampton, Southampton, UK.

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January 2004

Is trisomy 5 a distinct cytogenetic subgroup in acute lymphoblastic leukemia?

Cancer Genet Cytogenet 2004 Jan;148(2):159-62

Cancer Sciences Division, University of Southampton, MP 822, Duthie Building, Southampton General Hospital, SO16 6YD Southampton, UK.

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January 2004

Outcome heterogeneity in childhood high-hyperdiploid acute lymphoblastic leukemia.

Blood 2003 Oct 26;102(8):2756-62. Epub 2003 Jun 26.

Leukaemia Research Fund Cytogenetics Group, Cancer Sciences Division, University of Southampton, MP 822, Duthie Bldg, Southampton General Hospital, Southampton, SO16 6YD, United Kingdom.

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October 2003

Sex ratios and the risks of haematological malignancies.

Br J Haematol 2002 Sep;118(4):1071-7

Leukaemia Research Fund Centre for Clinical Epidemiology at the University of Leeds, Leeds, UK.

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September 2002

Genetic polymorphisms in microsomal epoxide hydrolase and susceptibility to adult acute myeloid leukaemia with defined cytogenetic abnormalities.

Br J Haematol 2002 Mar;116(3):587-94

Molecular Epidemiology Unit, Epidemiology and Health Services Research, School of Medicine, University of Leeds, UK.

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March 2002