Publications by authors named "Anthony P West"

66Publications

Electron tomography visualization of HIV-1 fusion with target cells using fusion inhibitors to trap the pre-hairpin intermediate.

Elife 2020 07 22;9. Epub 2020 Jul 22.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.

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http://dx.doi.org/10.7554/eLife.58411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394545PMC
July 2020

Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies.

Elife 2017 05 26;6. Epub 2017 May 26.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.

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http://dx.doi.org/10.7554/eLife.27389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472438PMC
May 2017

Structure of an HIV-2 gp120 in Complex with CD4.

J Virol 2016 02 25;90(4):2112-8. Epub 2015 Nov 25.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA

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http://dx.doi.org/10.1128/JVI.02678-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733984PMC
February 2016

Anti-PolyQ Antibodies Recognize a Short PolyQ Stretch in Both Normal and Mutant Huntingtin Exon 1.

J Mol Biol 2015 Jul 3;427(15):2507-2519. Epub 2015 Jun 3.

Division of Biology and Biological Engineering, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA; Howard Hughes Medical Institute, 4000 Jones Bridge Road, Chevy Chase, MD 20815-6789, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2015.05.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520773PMC
July 2015

CATNAP: a tool to compile, analyze and tally neutralizing antibody panels.

Nucleic Acids Res 2015 Jul 4;43(W1):W213-9. Epub 2015 Jun 4.

Los Alamos National Laboratory, Los Alamos, NM, USA

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http://dx.doi.org/10.1093/nar/gkv404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489231PMC
July 2015

Antibody engineering for increased potency, breadth and half-life.

Curr Opin HIV AIDS 2015 May;10(3):151-9

aDivision of Biology and Biological Engineering, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA bHoward Hughes Medical Institute, Chevy Chase, MD 20815-6789, USA.

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http://dx.doi.org/10.1097/COH.0000000000000148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465343PMC
May 2015

Intra-spike crosslinking overcomes antibody evasion by HIV-1.

Cell 2015 Jan;160(3):433-46

Division of Biology and Biological Engineering, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA; Howard Hughes Medical Institute. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.01.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401576PMC
January 2015

Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants.

J Exp Med 2014 Nov 10;211(12):2361-72. Epub 2014 Nov 10.

Laboratory of Molecular Immunology and Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065 Laboratory of Molecular Immunology and Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065.

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http://dx.doi.org/10.1084/jem.20141050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235636PMC
November 2014

Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike.

Cell Rep 2014 May 24;7(3):785-95. Epub 2014 Apr 24.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247140028
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http://dx.doi.org/10.1016/j.celrep.2014.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109818PMC
May 2014

Structural insights on the role of antibodies in HIV-1 vaccine and therapy.

Cell 2014 Feb;156(4):633-48

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA; Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674140014
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http://dx.doi.org/10.1016/j.cell.2014.01.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041625PMC
February 2014

Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12.

Cell Rep 2013 Dec 5;5(5):1443-55. Epub 2013 Dec 5.

Division of Biology and Biological Engineering 114-96, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA; Howard Hughes Medical Institute, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2013.11.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919625PMC
December 2013

Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues.

Proc Natl Acad Sci U S A 2013 Jun 10;110(26):10598-603. Epub 2013 Jun 10.

Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.1309215110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696754PMC
June 2013

Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody.

Proc Natl Acad Sci U S A 2013 Apr 22;110(15):6049-54. Epub 2013 Mar 22.

Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.1303682110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625305PMC
April 2013

Antibody gene transfer for HIV immunoprophylaxis.

Nat Immunol 2013 Jan;14(1):1-5

Division of Biology, California Institute of Technology, Pasadena, California, USA.

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http://dx.doi.org/10.1038/ni.2480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560170PMC
January 2013

The mammalian gene function resource: the International Knockout Mouse Consortium.

Mamm Genome 2012 Oct 12;23(9-10):580-6. Epub 2012 Sep 12.

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

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http://dx.doi.org/10.1007/s00335-012-9422-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463800PMC
October 2012

Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120.

Proc Natl Acad Sci U S A 2012 Jul 27;109(30):E2083-90. Epub 2012 Jun 27.

Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.1208984109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409792PMC
July 2012

Single-chain Fv-based anti-HIV proteins: potential and limitations.

J Virol 2012 Jan 19;86(1):195-202. Epub 2011 Oct 19.

Division of Biology, California Institute of Technology, Pasadena, California, USA.

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http://dx.doi.org/10.1128/JVI.05848-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255864PMC
January 2012

Dimeric 2G12 as a potent protection against HIV-1.

PLoS Pathog 2010 Dec 16;6(12):e1001225. Epub 2010 Dec 16.

Division of Biology, California Institute of Technology, Pasadena, California, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1001225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002980PMC
December 2010

Crystal structure of a hemojuvelin-binding fragment of neogenin at 1.8Å.

J Struct Biol 2011 Apr 28;174(1):239-44. Epub 2010 Oct 28.

Graduate Option in Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1016/j.jsb.2010.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074981PMC
April 2011

Crystal structure of TNFalpha complexed with a poxvirus MHC-related TNF binding protein.

Nat Struct Mol Biol 2009 Nov 18;16(11):1189-91. Epub 2009 Oct 18.

Division of Biology 114-96, California Institute of Technology, Pasadena, California, USA.

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http://dx.doi.org/10.1038/nsmb.1683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819277PMC
November 2009

Examination of the contributions of size and avidity to the neutralization mechanisms of the anti-HIV antibodies b12 and 4E10.

Proc Natl Acad Sci U S A 2009 May 16;106(18):7385-90. Epub 2009 Apr 16.

Graduate option in Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.0811427106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678646PMC
May 2009

The crystal structure of CHIR-AB1: a primordial avian classical Fc receptor.

J Mol Biol 2008 Sep 3;381(4):1012-24. Epub 2008 Jul 3.

Division of Biology, 114-96 and Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1016/j.jmb.2008.06.082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2603183PMC
September 2008

Neogenin interacts with hemojuvelin through its two membrane-proximal fibronectin type III domains.

Biochemistry 2008 Apr 13;47(14):4237-45. Epub 2008 Mar 13.

Graduate Option in Chemistry, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1021/bi800036hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819367PMC
April 2008

Extension of Drosophila melanogaster life span with a GPCR peptide inhibitor.

Nat Chem Biol 2007 Jul 3;3(7):415-9. Epub 2007 Jun 3.

Division of Biology, 1200 E. California Blvd. 156-29, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1038/nchembio.2007.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803097PMC
July 2007

The structure of a polyQ-anti-polyQ complex reveals binding according to a linear lattice model.

Nat Struct Mol Biol 2007 May 22;14(5):381-7. Epub 2007 Apr 22.

Division of Biology 114-96, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1038/nsmb1234DOI Listing
May 2007

FcRn mediates elongated serum half-life of human IgG in cattle.

Int Immunol 2006 Apr 15;18(4):525-36. Epub 2006 Feb 15.

Department of Physiology and Biochemistry, Faculty of Veterinary Science, Szent István University, Budapest, Hungary.

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http://dx.doi.org/10.1093/intimm/dxh393DOI Listing
April 2006

Zn-alpha2-glycoprotein, an MHC class I-related glycoprotein regulator of adipose tissues: modification or abrogation of ligand binding by site-directed mutagenesis.

Biochemistry 2006 Feb;45(7):2035-41

Division of Environmental and Evolutionary Biology, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, Scotland, UK.

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http://dx.doi.org/10.1021/bi051881vDOI Listing
February 2006

Crystal structure of the S.cerevisiae exocyst component Exo70p.

J Mol Biol 2006 Feb 10;356(1):9-21. Epub 2005 Nov 10.

Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305-5126, USA.

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http://dx.doi.org/10.1016/j.jmb.2005.09.099DOI Listing
February 2006

Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells.

J Biol Chem 2005 Oct 15;280(40):33885-94. Epub 2005 Aug 15.

Department of Cell and Developmental Biology, Oregon Health & Science University, Portland, Oregon 97239, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M506207200
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http://dx.doi.org/10.1074/jbc.M506207200DOI Listing
October 2005

Crystal structure of a secreted insect ferritin reveals a symmetrical arrangement of heavy and light chains.

J Mol Biol 2005 Jun 12;349(3):558-69. Epub 2005 Apr 12.

Division of Biology 114-96, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1016/j.jmb.2005.03.074DOI Listing
June 2005

Crystal structure of a polymeric immunoglobulin binding fragment of the human polymeric immunoglobulin receptor.

Structure 2004 Nov;12(11):1925-35

Division of Biology 114-96, California Institute of Technology, Pasadena, CA 91125, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S096921260400332
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http://dx.doi.org/10.1016/j.str.2004.09.006DOI Listing
November 2004

Crystallographic studies of ligand binding by Zn-alpha2-glycoprotein.

J Struct Biol 2004 Nov;148(2):205-13

Division of Biology, 114-96 Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1016/j.jsb.2004.04.009DOI Listing
November 2004

The chicken yolk sac IgY receptor, a functional equivalent of the mammalian MHC-related Fc receptor, is a phospholipase A2 receptor homolog.

Immunity 2004 May;20(5):601-10

Division of Biology 114-96, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1016/s1074-7613(04)00113-xDOI Listing
May 2004

Initial sequencing and comparative analysis of the mouse genome.

Authors:
Robert H Waterston Kerstin Lindblad-Toh Ewan Birney Jane Rogers Josep F Abril Pankaj Agarwal Richa Agarwala Rachel Ainscough Marina Alexandersson Peter An Stylianos E Antonarakis John Attwood Robert Baertsch Jonathon Bailey Karen Barlow Stephan Beck Eric Berry Bruce Birren Toby Bloom Peer Bork Marc Botcherby Nicolas Bray Michael R Brent Daniel G Brown Stephen D Brown Carol Bult John Burton Jonathan Butler Robert D Campbell Piero Carninci Simon Cawley Francesca Chiaromonte Asif T Chinwalla Deanna M Church Michele Clamp Christopher Clee Francis S Collins Lisa L Cook Richard R Copley Alan Coulson Olivier Couronne James Cuff Val Curwen Tim Cutts Mark Daly Robert David Joy Davies Kimberly D Delehaunty Justin Deri Emmanouil T Dermitzakis Colin Dewey Nicholas J Dickens Mark Diekhans Sheila Dodge Inna Dubchak Diane M Dunn Sean R Eddy Laura Elnitski Richard D Emes Pallavi Eswara Eduardo Eyras Adam Felsenfeld Ginger A Fewell Paul Flicek Karen Foley Wayne N Frankel Lucinda A Fulton Robert S Fulton Terrence S Furey Diane Gage Richard A Gibbs Gustavo Glusman Sante Gnerre Nick Goldman Leo Goodstadt Darren Grafham Tina A Graves Eric D Green Simon Gregory Roderic Guigó Mark Guyer Ross C Hardison David Haussler Yoshihide Hayashizaki LaDeana W Hillier Angela Hinrichs Wratko Hlavina Timothy Holzer Fan Hsu Axin Hua Tim Hubbard Adrienne Hunt Ian Jackson David B Jaffe L Steven Johnson Matthew Jones Thomas A Jones Ann Joy Michael Kamal Elinor K Karlsson Donna Karolchik Arkadiusz Kasprzyk Jun Kawai Evan Keibler Cristyn Kells W James Kent Andrew Kirby Diana L Kolbe Ian Korf Raju S Kucherlapati Edward J Kulbokas David Kulp Tom Landers J P Leger Steven Leonard Ivica Letunic Rosie Levine Jia Li Ming Li Christine Lloyd Susan Lucas Bin Ma Donna R Maglott Elaine R Mardis Lucy Matthews Evan Mauceli John H Mayer Megan McCarthy W Richard McCombie Stuart McLaren Kirsten McLay John D McPherson Jim Meldrim Beverley Meredith Jill P Mesirov Webb Miller Tracie L Miner Emmanuel Mongin Kate T Montgomery Michael Morgan Richard Mott James C Mullikin Donna M Muzny William E Nash Joanne O Nelson Michael N Nhan Robert Nicol Zemin Ning Chad Nusbaum Michael J O'Connor Yasushi Okazaki Karen Oliver Emma Overton-Larty Lior Pachter Genís Parra Kymberlie H Pepin Jane Peterson Pavel Pevzner Robert Plumb Craig S Pohl Alex Poliakov Tracy C Ponce Chris P Ponting Simon Potter Michael Quail Alexandre Reymond Bruce A Roe Krishna M Roskin Edward M Rubin Alistair G Rust Ralph Santos Victor Sapojnikov Brian Schultz Jörg Schultz Matthias S Schwartz Scott Schwartz Carol Scott Steven Seaman Steve Searle Ted Sharpe Andrew Sheridan Ratna Shownkeen Sarah Sims Jonathan B Singer Guy Slater Arian Smit Douglas R Smith Brian Spencer Arne Stabenau Nicole Stange-Thomann Charles Sugnet Mikita Suyama Glenn Tesler Johanna Thompson David Torrents Evanne Trevaskis John Tromp Catherine Ucla Abel Ureta-Vidal Jade P Vinson Andrew C Von Niederhausern Claire M Wade Melanie Wall Ryan J Weber Robert B Weiss Michael C Wendl Anthony P West Kris Wetterstrand Raymond Wheeler Simon Whelan Jamey Wierzbowski David Willey Sophie Williams Richard K Wilson Eitan Winter Kim C Worley Dudley Wyman Shan Yang Shiaw-Pyng Yang Evgeny M Zdobnov Michael C Zody Eric S Lander

Nature 2002 Dec;420(6915):520-62

Genome Sequencing Center, Washington University School of Medicine, Campus Box 8501, 4444 Forest Park Avenue, St Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1038/nature01262DOI Listing
December 2002

A linear lattice model for polyglutamine in CAG-expansion diseases.

Proc Natl Acad Sci U S A 2002 Sep 22;99(18):11634-9. Epub 2002 Aug 22.

Division of Biology, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.182393899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC129321PMC
September 2002