Anthony M Giannetti

Anthony M Giannetti

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Anthony M Giannetti

Anthony M Giannetti

Publications by authors named "Anthony M Giannetti"

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Development of a Model Protein Interaction Pair as a Benchmarking Tool for the Quantitative Analysis of 2-Site Protein-Protein Interactions.

J Biomol Tech 2015 Dec 29;26(4):125-41. Epub 2015 Oct 29.

1 Bristol-Myers Squibb, Princeton, New Jersey 08540, USA; 2 Tokyo Institute of Technology, Yokohama 226-8503, Japan; 3 Google[x], Google Life Sciences, Mountain View, California 94043, USA; 4 SystaMedic, Incorporated, Groton, Connecticut 06340, USA; 5 Biosensor Tools LLC, Salt Lake City, Utah 84103, USA; 6 National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA; 7 Polaris Pharmaceuticals, Incorporated, San Diego, California 92121, USA; and 8 Institute for Bioscience and Biotechnology Research, Fischell Department of Bioengineering, University of Maryland, Rockville, Maryland 20850, USA.

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http://dx.doi.org/10.7171/jbt.15-2604-001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627511PMC
December 2015

Atom-Atom-Path similarity and Sphere Exclusion clustering: tools for prioritizing fragment hits.

J Cheminform 2015 25;7:11. Epub 2015 Mar 25.

Small Molecule Discovery, Discovery Chemistry, Genentech, 1 DNA Way, 94080 South San Francisco, CA USA.

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http://dx.doi.org/10.1186/s13321-015-0056-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392110PMC
April 2015

Internal motions prime cIAP1 for rapid activation.

Nat Struct Mol Biol 2014 Dec 10;21(12):1068-74. Epub 2014 Nov 10.

Department of Early Discovery Biochemistry, Genentech, South San Francisco, California, USA.

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http://dx.doi.org/10.1038/nsmb.2916DOI Listing
December 2014

Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors.

Bioorg Med Chem Lett 2014 Sep 2;24(18):4546-4552. Epub 2014 Aug 2.

Department of Discovery Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.07.071DOI Listing
September 2014

Structure of the BRAF-MEK complex reveals a kinase activity independent role for BRAF in MAPK signaling.

Cancer Cell 2014 Sep 21;26(3):402-413. Epub 2014 Aug 21.

Department of Biochemical and Cellular Pharmacology, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.07.007DOI Listing
September 2014

Tailoring small molecules for an allosteric site on procaspase-6.

ChemMedChem 2014 Jan 20;9(1):73-7, 2. Epub 2013 Nov 20.

Departments of Structural Biology, Biochemical Pharmacology, Neuroscience, and Discovery Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080 (USA).

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http://dx.doi.org/10.1002/cmdc.201300424DOI Listing
January 2014

From experimental design to validated hits a comprehensive walk-through of fragment lead identification using surface plasmon resonance.

Methods Enzymol 2011 ;493:169-218

Genentech Inc., 1 DNA Way, South San Francisco, California, USA.

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http://dx.doi.org/10.1016/B978-0-12-381274-2.00008-XDOI Listing
June 2011

Docking for fragment inhibitors of AmpC beta-lactamase.

Proc Natl Acad Sci U S A 2009 May 22;106(18):7455-60. Epub 2009 Apr 22.

Department of Pharmaceutical Chemistry, University of California, 1700 4th Street, MC 2550, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1073/pnas.0813029106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671983PMC
May 2009

A global benchmark study using affinity-based biosensors.

Authors:
Rebecca L Rich Giuseppe A Papalia Peter J Flynn Jamie Furneisen John Quinn Joshua S Klein Phini S Katsamba M Brent Waddell Michael Scott Joshua Thompson Judie Berlier Schuyler Corry Mireille Baltzinger Gabrielle Zeder-Lutz Andreas Schoenemann Anca Clabbers Sebastien Wieckowski Mary M Murphy Phillip Page Thomas E Ryan Jay Duffner Tanmoy Ganguly John Corbin Satyen Gautam Gregor Anderluh Andrej Bavdek Dana Reichmann Satya P Yadav Eric Hommema Ewa Pol Andrew Drake Scott Klakamp Trevor Chapman Dawn Kernaghan Ken Miller Jason Schuman Kevin Lindquist Kara Herlihy Michael B Murphy Richard Bohnsack Bruce Andrien Pietro Brandani Danny Terwey Rohn Millican Ryan J Darling Liann Wang Quincy Carter Joe Dotzlaf Jacinto Lopez-Sagaseta Islay Campbell Paola Torreri Sylviane Hoos Patrick England Yang Liu Yasmina Abdiche Daniel Malashock Alanna Pinkerton Melanie Wong Eileen Lafer Cynthia Hinck Kevin Thompson Carmelo Di Primo Alison Joyce Jonathan Brooks Federico Torta Anne Birgitte Bagge Hagel Janus Krarup Jesper Pass Monica Ferreira Sergei Shikov Malgorzata Mikolajczyk Yuki Abe Gaetano Barbato Anthony M Giannetti Ganeshram Krishnamoorthy Bianca Beusink Daulet Satpaev Tiffany Tsang Eric Fang James Partridge Stephen Brohawn James Horn Otto Pritsch Gonzalo Obal Sanjay Nilapwar Ben Busby Gerardo Gutierrez-Sanchez Ruchira Das Gupta Sylvie Canepa Krista Witte Zaneta Nikolovska-Coleska Yun Hee Cho Roberta D'Agata Kristian Schlick Rosy Calvert Eva M Munoz Maria Jose Hernaiz Tsafir Bravman Monica Dines Min-Hsiang Yang Agnes Puskas Erica Boni Jiejin Li Martin Wear Asya Grinberg Jason Baardsnes Olan Dolezal Melicia Gainey Henrik Anderson Jinlin Peng Mark Lewis Peter Spies Quyhn Trinh Sergei Bibikov Jill Raymond Mohammed Yousef Vidya Chandrasekaran Yuguo Feng Anne Emerick Suparna Mundodo Rejane Guimaraes Katy McGirr Yue-Ji Li Heather Hughes Hubert Mantz Rostislav Skrabana Mark Witmer Joshua Ballard Loic Martin Petr Skladal George Korza Ite Laird-Offringa Charlene S Lee Abdelkrim Khadir Frank Podlaski Phillippe Neuner Julie Rothacker Ashique Rafique Nico Dankbar Peter Kainz Erk Gedig Momchilo Vuyisich Christina Boozer Nguyen Ly Mark Toews Aykut Uren Oleksandr Kalyuzhniy Kenneth Lewis Eugene Chomey Brian J Pak David G Myszka

Anal Biochem 2009 Mar 27;386(2):194-216. Epub 2008 Nov 27.

Center for Biomolecular Interaction Analysis, School of Medicine, University of Utah, Salt Lake City, UT 84132, USA.

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http://dx.doi.org/10.1016/j.ab.2008.11.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793259PMC
March 2009

Thermodynamic characterization of pyrazole and azaindole derivatives binding to p38 mitogen-activated protein kinase using Biacore T100 technology and van't Hoff analysis.

Anal Biochem 2008 Dec 19;383(2):255-64. Epub 2008 Aug 19.

Center for Biomolecular Interaction Analysis, University of Utah, Salt Lake City, UT 84132, USA.

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http://dx.doi.org/10.1016/j.ab.2008.08.010DOI Listing
December 2008

Molecular mechanism of the Syk activation switch.

J Biol Chem 2008 Nov 25;283(47):32650-9. Epub 2008 Sep 25.

Department of Inflammation Discovery, Roche Palo Alto LLC, Palo Alto, California 94304, USA.

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http://dx.doi.org/10.1074/jbc.M806340200DOI Listing
November 2008

The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression.

Cell Metab 2008 Mar;7(3):205-14

Division of Hematology/Oncology, Children's Hospital Boston, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.cmet.2007.11.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292811PMC
March 2008

Surface plasmon resonance based assay for the detection and characterization of promiscuous inhibitors.

J Med Chem 2008 Feb 9;51(3):574-80. Epub 2008 Jan 9.

Roche Palo Alto LLC, Palo Alto, CA 94304, USA.

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http://dx.doi.org/10.1021/jm700952vDOI Listing
February 2008

Thermodynamics of calmodulin trapping by Ca2+/calmodulin-dependent protein kinase II: subpicomolar Kd determined using competition titration calorimetry.

Biochemistry 2007 Apr 13;46(13):4017-27. Epub 2007 Mar 13.

Department of Biochemical Pharmacology, Roche Palo Alto LLC, 3431 Hillview Avenue, Palo Alto, California 94304, USA.

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http://pubs.acs.org/doi/abs/10.1021/bi700013y
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http://dx.doi.org/10.1021/bi700013yDOI Listing
April 2007

Effect of glycosylation on the function of a soluble, recombinant form of the transferrin receptor.

Biochemistry 2006 May;45(21):6663-73

Department of Biochemistry, University of Vermont College of Medicine, Burlington, Vermont 05405-0068, USA.

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http://dx.doi.org/10.1021/bi0600695DOI Listing
May 2006

The molecular mechanism for receptor-stimulated iron release from the plasma iron transport protein transferrin.

Structure 2005 Nov;13(11):1613-23

Division of Biology 114-96, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1016/j.str.2005.07.016DOI Listing
November 2005

HFE and transferrin directly compete for transferrin receptor in solution and at the cell surface.

J Biol Chem 2004 Jun 31;279(24):25866-75. Epub 2004 Mar 31.

Graduate Option in Biochemistry and Molecular Biophysics, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1074/jbc.M401467200DOI Listing
June 2004

Mechanism for multiple ligand recognition by the human transferrin receptor.

PLoS Biol 2003 Dec 22;1(3):E51. Epub 2003 Dec 22.

Graduate Option in Biochemistry and Molecular Biophysics, California Institute of Technology, Pasadena, California, USA.

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http://dx.doi.org/10.1371/journal.pbio.0000051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC300677PMC
December 2003

Heterotypic interactions between transferrin receptor and transferrin receptor 2.

Blood 2003 Mar 24;101(5):2008-14. Epub 2002 Oct 24.

Department of Cell and Developmental Biology, Oregon Health and Science University, Portland OR 97201-3098, USA.

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http://dx.doi.org/10.1182/blood-2002-09-2742DOI Listing
March 2003